CN103393964A - Medicament for treating gastric fever and preparation method thereof - Google Patents
Medicament for treating gastric fever and preparation method thereof Download PDFInfo
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- CN103393964A CN103393964A CN201310323355XA CN201310323355A CN103393964A CN 103393964 A CN103393964 A CN 103393964A CN 201310323355X A CN201310323355X A CN 201310323355XA CN 201310323355 A CN201310323355 A CN 201310323355A CN 103393964 A CN103393964 A CN 103393964A
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Abstract
The invention discloses a medicament for treating gastric fever and a preparation method thereof. The medicament is mainly prepared from medicaments including rhinoceros horn, coptis root, gardenia, scutellaria root, dried rehmannia root, radix paeoniae alba and the like according to a certain weight ratio. The medicament disclosed by the invention has the effects of nourishing yin and moistening the lung, nourishing yin and falling fire as well as clearing heat and cooling blood, and is quick in response, good in curative effect and high in cure rate when used for treating gastric fever.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of gastric heat and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Gastric heat is namely stomach-fire.The traditional Chinese medical science is divided into inflammation and burning hot tenesmus etc. on heat stagnating in the stomach, pathogenic fire.How by heat invading the stomach; Or, because being addicted to drink, having a liking for pungent, the surfeit greasy and surfeit flavour of food, help fiery heat-dissipating; Or because of the stagnation of QI, blood stasis, expectorant, pent-up heat-transformation, the fire-transformation such as wet, food stagnation, all can cause gastric heat; Gastric heat is many, and the stomach-fire element is prosperous, or heat invading the stomach by the pungent savoury of monophagia, or due to stagnated QI transforming into fire.Vehement in burning hot, stomach internal organs venation stagnation of QI-blood, thus the scorching hot pain of gastral cavity section, the pathogenic heat impairment of body fluid, thirst and liking cold drink, fire can rapid digestion of food, rapid digestion of food and polyorexia; If liver-fire invading the stomach, acid regurgitation and epigastric upset; Pathogenic fire is followed through upper inflammation, halitosis, gingival swelling and pain, epistaxis etc.Because Western medicine can't effectively be treated gastric heat, and the long-term taking Western medicine has more side effect, and therefore, there is very large demand in people to the Chinese medicine of effective treatment gastric heat.
Summary of the invention
The inventor, according to the research of theory of Chinese medical science and clinical repeatedly test and checking, has finally found the medicine of effective treatment gastric heat, thereby has completed the present invention.
Purpose of the present invention just is to provide a kind of composition of medicine that can effectively treat gastric heat.
Another object of the present invention just has been to provide the preparation method of this composition of medicine.
Medicine of the present invention selects Cornu rhinocerotis, Rhizoma Coptidis, Fructus Gardeniae, Radix Scutellariae, Radix Rehmanniae, Radix Paeoniae Alba, Nodus Nelumbinis Rhizomatis, Rhizoma Imperatae, Radix Notoginseng, Semen Nelumbinis, Radix Angelicae Sinensis, Radix Codonopsis medicine to make up, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat the recurrence of gastric heat.Wherein select Cornu rhinocerotis to be because its nature and flavor acid is salty, cold, enter the heart, Liver Channel, heat clearing away is arranged, removing heat from blood, arresting convulsion, the function of detoxifcation, the cold pestilence pathogenic heat attacking blood system in febrile diseases that cures the wound, mania and irritation, agitation, delirium, macule, jaundice, spit blood, epistaxis, hematochezia, swollen ulcer drug.Select Rhizoma Coptidis to be because its nature and flavor hardship is cold, enter the heart, liver, stomach, large intestine channel, pathogenic fire purging is arranged, dampness, detoxifcation, the function of parasite killing, row pyretic toxicity, typhoid fever while controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, diarrhea of heat type stomachache, pulmonary tuberculosis, tell, nosebleed, hematochezia, quenches one's thirst, and infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Select Fructus Gardeniae to be because its nature and flavor hardship is cold, enter the heart, liver, lung, stomach warp, heat clearing away is arranged, pathogenic fire purging, the function of removing heat from blood, control the calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprain and swell and ache.Select Radix Scutellariae to be because its nature and flavor bitter cold enters cardiopulmonary, gallbladder, large intestine channel, the removing the relative excess fire is arranged, except damp and hot, the function of arresting bleeding and miscarriage prevention, control the high fever excessive thirst, the cough due to lung-heat.Select Radix Rehmanniae to be because its nature and flavor are sweet, cold, GUIXIN, liver, kidney channel, have clearing away heat and cooling blood, yin nourishing, and the function of promoting the production of body fluid, control the calentura excessive thirst, yin asthenia generating intrinsic heat, the hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis, send out the speckle dermexanthesis.Select Radix Paeoniae Alba to be because its nature and flavor picric acid is cool, enter liver, spleen channel, nourishing blood to suppress the hyperactive liver is arranged, slow middle pain relieving, yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.Select Nodus Nelumbinis Rhizomatis to be because its property sweet-puckery flavor is flat, few the moon of starting with, the foot sun is bright, and JUE YIN meridian, have hemostasis, and the function of dissipating blood stasis, control hemoptysis, spits blood, epistaxis, hematuria, have blood in stool, dysentery, metrorrhagia.It is sweet because of its nature and flavor, cold selecting Rhizoma Imperatae, enters lung, stomach, small intestine meridian, and removing heat from blood is arranged, hemostasis, and heat clearing away, the function of diuresis, control the calentura excessive thirst, spits blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Selecting Radix Notoginseng is that temperature, enter liver, stomach, large intestine channel, and hemostasis is arranged because of its property sweet and slightly bitter taste, dissipating blood stasis, and detumescence, the function of analgesic therapy, control haematemesis, hemoptysis, epistaxis, have blood in stool, dysentery, metrorrhagia, mass in the abdomen, puerperal blood faints, retention of lochia, fall and flutter blood stasis, traumatic hemorrhage, carbuncle pain.Select Semen Nelumbinis to be because its property sweet-puckery flavor is flat, enter the heart, spleen, kidney channel, nourish heart, kidney tonifying, spleen reinforcing, the function of astringing intestine to stop diarrhea, control the dreaminess of sleeping night, seminal emission, stranguria with turbid discharge, chronic dysentery, diarrhea of deficiency type, married woman's bleeding not during menses.Select Radix Angelicae Sinensis to be because its nature and flavor sweet, acrid, warm enters the heart, liver, spleen channel, benefiting blood and regulating blood circulation is arranged, menstruction regulating and pain relieving, the function of moisturizing laxation, control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia, and headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome, dryness of the intestine difficulty are just, and be heavy after bloody dysentery, ulcer sores, incised wound, injury from falling down.Select Radix Codonopsis to be because its nature and flavor are sweet, flat, start with, the meridian of Foot-TAI YIN edema caused by disorder of QI, invigorating the spleen and replenishing QI is arranged, the function of promoting the production of body fluid, control weakness of the spleen and stomach, deficiency of both QI and blood, and fatigue and lack of strength, lack of appetite, thirsty, chronic diarrhea, proctoptosis.
The specific embodiment
The drug dose of the present invention's combination is also that the inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect in the following weight scope
Cornu rhinocerotis 8-15 gram Rhizoma Coptidis 8-15 gram Fructus Gardeniae 10-20 grams
Radix Scutellariae 10-20 gram Radix Rehmanniae 10-20 gram Radix Paeoniae Alba 10-20 grams
Nodus Nelumbinis Rhizomatis 10-20 gram Rhizoma Imperatae 10-20 gram Radix Notoginseng 8-15 grams
Semen Nelumbinis 8-15 gram Radix Angelicae Sinensis 8-15 gram Radix Codonopsis 8-15 grams
Preferable amount is
Cornu rhinocerotis 10 gram Rhizoma Coptidis 10 gram Fructus Gardeniae 15 grams
Radix Scutellariae 15 gram Radix Rehmanniae 15 gram Radix Paeoniae Alba 15 grams
Nodus Nelumbinis Rhizomatis 15 gram Rhizoma Imperatae 15 gram Radix Notoginseng 10 grams
Semen Nelumbinis 10 gram Radix Angelicae Sinensis 10 gram Radix Codonopsis 10 grams
The preparation method of medicine of the present invention is as follows
One, get the raw materials ready
1, Cornu rhinocerotis: get Cornu rhinocerotis and be split into lobe, put in warm water and soak, pull out, the pound sheet, dry;
2, Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section, dry in the shade;
3, Fructus Gardeniae: sieve dedust bits, choose decontamination, pulverize and sieve or cut off two ends;
4, Radix Scutellariae: choose decontamination, remove residual stem, with cold water, infiltrate or put in boiled water and slightly soak and pull out, section, dry;
5, Radix Rehmanniae: get crude drug, remove impurity, clean, slightly profit, cut sheet, drying, and sieve removes chip;
6, Radix Paeoniae Alba: choose decontamination, size separately, be soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;
7, Nodus Nelumbinis Rhizomatis: get clean Nodus Nelumbinis Rhizomatis and put in pot and fry and to be black to outside, inside is strong yellow, slightly spills clear water, takes out drying;
8, Rhizoma Imperatae: choose clean impurity, clean, micro-profit, cutting, dry, the clean chip of winnowing with a dustpan;
9, Radix Notoginseng: choose most impurity, smash to pieces, grind or run through section into powder and dry;
10, Semen Nelumbinis: choose most impurity, or smash, remove the peel, go the heart to use;
11, Radix Angelicae Sinensis: choose decontamination, clean, run through, section is dried;
12, Radix Codonopsis: after cleaning silt, run through reed, section or cutting, dry.
Two, preparation
1, the Cornu rhinocerotis of described weight, Rhizoma Coptidis, Fructus Gardeniae, Radix Scutellariae, Radix Rehmanniae, Radix Paeoniae Alba, Nodus Nelumbinis Rhizomatis, Rhizoma Imperatae, Radix Notoginseng, Semen Nelumbinis, Radix Angelicae Sinensis, Radix Codonopsis are decocted with water, add for the first time 6 times of amounts of water, intense fire decocts boiling 15 minutes, used again slow fire boiling 20 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time.
2, the medicinal residues after filtering add 4 times of amounts of water, decoct boiling, then use slow fire boiling 25 minutes, filter to obtain decoction liquor for the second time.
3, twice decoction liquor merged, boil with high heat, then used slow fire boiling 10 minutes, obtain medicinal liquid, will decoct medicinal liquid and be divided into 3 doses and take.
Medicine of the present invention has nourishing YIN and moistening the lung, nourishing YIN to lower pathogenic fire, and heat clearing away, removing heat from blood, the effect of dampness, treatment gastric heat instant effect, short treating period, do not recur.
Below by test example, further set forth the beneficial effect of medicine of the present invention, these tests comprise animal toxicity test report and the clinical observation material of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get 30 of rabbit, the male and female dual-purpose, body weight 2.0-2.5kg, divide two groups, and 15 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is the administration by gavage administration, every day twice, serve on 7 days, observes the administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 240 examples for medical treatment.
2, diagnostic criteria
The performance of gastric heat has following characteristics: gastral cavity section causalgia, vomit bitter, thirst and desire for cold drink, constipation, red tongue with yellow fur, slippery and rapid pulse.Stomach excessive heat, the function of becoming thoroughly decomposed is too hyperfunction, the diseases such as epigastric upset, rapid digestion of food and polyorexia can occur, the intenseness of heat heated, the bright body fluid that disappears more, and cause dryness-heat stagnating in the interior, stomach-QI being unable to descend normally, the diseases such as visible bitter taste, thirst and drinking, constipation.Very consume impairment of YIN liquid and cause deficiency of stomach-YIN.Flaming up of stomach-fire, can cause adverse rising of stomach-QI, visible feels sick, the disease such as vomting sour,bitter and yellow liquids.Stomach-fire upward flaming along the meridian, or be the toothache swelling of the gum, or be epistaxis, the venation of the stomach of intimately burning, blood overflow and be hematemesis.
3, Therapeutic Method
Select above-mentioned medicament, to the patient, take, each serving with 1 dose, every day early, respectively take 1 evening, and 7 days is a course for the treatment of, takes continuously 4 courses for the treatment of.
4, efficacy assessment standard
Produce effects: gastric heat is eliminated, and observes after half a year without recurrence;
Take a turn for the better: the gastric heat symptom is clearly better;
Invalid: symptom, without improvement, does not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, with Drug therapy gastric heat patient of the present invention 240 examples, produce effects 230 examples as a result, obvious effective rate is 95.83%, 6 examples that take a turn for the better, improvement rate is 2.5%, invalid 4 examples, total effective rate is 98.33%.
Claims (3)
1. medicine for the treatment of gastric heat, it is characterized in that: it is to be made by the crude drug in following weight range:
Cornu rhinocerotis 8-15 gram Rhizoma Coptidis 8-15 gram Fructus Gardeniae 10-20 grams
Radix Scutellariae 10-20 gram Radix Rehmanniae 10-20 gram Radix Paeoniae Alba 10-20 grams
Nodus Nelumbinis Rhizomatis 10-20 gram Rhizoma Imperatae 10-20 gram Radix Notoginseng 8-15 grams
Semen Nelumbinis 8-15 gram Radix Angelicae Sinensis 8-15 gram Radix Codonopsis 8-15 grams.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Cornu rhinocerotis 10 gram Rhizoma Coptidis 10 gram Fructus Gardeniae 15 grams
Radix Scutellariae 15 gram Radix Rehmanniae 15 gram Radix Paeoniae Alba 15 grams
Nodus Nelumbinis Rhizomatis 15 gram Rhizoma Imperatae 15 gram Radix Notoginseng 10 grams
Semen Nelumbinis 10 gram Radix Angelicae Sinensis 10 gram Radix Codonopsis 10 grams.
3. the preparation method of described medicine according to claim 1 and 2, it comprises the following steps:
(1) get the raw materials ready
(1) Cornu rhinocerotis: get Cornu rhinocerotis and be split into lobe, put in warm water and soak, pull out, the pound sheet, dry;
(2) Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section, dry in the shade;
(3) Fructus Gardeniae: sieve dedust bits, choose decontamination, pulverize and sieve or cut off two ends;
(4) Radix Scutellariae: choose decontamination, remove residual stem, with cold water, infiltrate or put in boiled water and slightly soak and pull out, section, dry;
(5) Radix Rehmanniae: get crude drug, remove impurity, clean, slightly profit, cut sheet, drying, and sieve removes chip;
(6) Radix Paeoniae Alba: choose decontamination, size separately, be soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;
(7) Nodus Nelumbinis Rhizomatis: get clean Nodus Nelumbinis Rhizomatis and put in pot and fry and to be black to outside, inside is strong yellow, slightly spills clear water, takes out drying;
(8) Rhizoma Imperatae: choose clean impurity, clean, micro-profit, cutting, dry, the clean chip of winnowing with a dustpan;
(9) Radix Notoginseng: choose most impurity, smash to pieces, grind or run through section into powder and dry;
(10) Semen Nelumbinis: choose most impurity, or smash, remove the peel, go the heart to use;
(11) Radix Angelicae Sinensis: choose decontamination, clean, run through, section is dried;
(12) Radix Codonopsis: after cleaning silt, run through reed, section or cutting, dry;
(2) preparation
(1) Cornu rhinocerotis of described weight, Rhizoma Coptidis, Fructus Gardeniae, Radix Scutellariae, Radix Rehmanniae, Radix Paeoniae Alba, Nodus Nelumbinis Rhizomatis, Rhizoma Imperatae, Radix Notoginseng, Semen Nelumbinis, Radix Angelicae Sinensis, Radix Codonopsis are decocted with water, add for the first time 6 times of amounts of water, intense fire decocts boiling 15 minutes, used again slow fire boiling 20 minutes, filter to obtain decoction liquor for the first time, decoction liquor is poured in container for the first time;
(2) medicinal residues after filtering add 4 times of amounts of water, decoct boiling, then use slow fire boiling 25 minutes, filter to obtain decoction liquor for the second time;
(3) twice decoction liquor merged, boil with high heat, then used slow fire boiling 10 minutes, obtain medicinal liquid, will decoct medicinal liquid and be divided into 3 doses and take.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189341A (en) * | 2014-08-19 | 2014-12-10 | 贵州黄平靓鸥桑综合开发有限公司 | Medicinal tea for reducing stomach fire |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101766804A (en) * | 2010-04-20 | 2010-07-07 | 泰一和浦（北京）中医药研究院有限公司 | Chinese herbal composite for epistaxis treatment and preparation method thereof |
| CN101879287A (en) * | 2010-06-28 | 2010-11-10 | 陈希杰 | Method for preparing traditional Chinese medicine for treating excessive-heating uterine bleeding |
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- 2013-07-30 CN CN201310323355XA patent/CN103393964A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101766804A (en) * | 2010-04-20 | 2010-07-07 | 泰一和浦（北京）中医药研究院有限公司 | Chinese herbal composite for epistaxis treatment and preparation method thereof |
| CN101879287A (en) * | 2010-06-28 | 2010-11-10 | 陈希杰 | Method for preparing traditional Chinese medicine for treating excessive-heating uterine bleeding |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189341A (en) * | 2014-08-19 | 2014-12-10 | 贵州黄平靓鸥桑综合开发有限公司 | Medicinal tea for reducing stomach fire |
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Application publication date: 20131120 |