CN103142871A - Obesity treatment medicine and its preparation method - Google Patents

Abstract

The invention discloses an obesity treatment medicine and its preparation method. The obesity treatment medicine is prepared through using haw, lotus leaf, Panax Notoginseng, leech, Salvia miltiorrhiza, Cassia Twig, Fortune Eupatorium Herb and the like according to certain weight proportions. The obesity treatment medicine has the functions of blood circulation activating, water supplementing, liver and gallbladder smoothing, and intestine and stomach maintenance, and has the advantages of fast effectiveness, good curative effect and high cure rate when the medicine is used for treating obesity.

Description

A kind of fat medicine and preparation method thereof for the treatment of

Technical field

The present invention relates to a kind of medicine for losing weight and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Obesity refers to that obvious overweight and fat deposit to a certain degree is blocked up, is body fat, and especially triglyceride gathers a kind of fat state that too much causes.Due to food intake too much or the change of organism metabolism cause body fat to gather too much causing excess weight to increase and cause human pathology, physiological change or hide.Obesity not only affects pretty figure, and has certain harm, with increase cardiovascular disease and cancer danger, affect the function of digestive system and hormonal system, make troubles to life.Cause easily that in addition soft tissue of joint damage, reproductive performance descend and mental maladjustment, bring out heart disease, diabetes, atherosclerosis, fatty liver, cholelithiasis, edema, gout etc., can say that obesity is the source of ten thousand diseases.At present, the fat poor effect of western medicine, and more side effect is arranged, therefore, there is very large demand in people to the fat Chinese medicine of effective treatment.

Summary of the invention

The inventor has finally found the fat medicine of effective treatment, thereby has completed the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.

Purpose of the present invention just is to provide a kind of composition of medicine that can effectively treat obesity.

Another object of the present invention just has been to provide the preparation method of this composition of medicine.

Medicine of the present invention selects Fructus Crataegi, Folium Nelumbinis, Rhizoma Imperatae, Rhizoma Phragmitis, Herba Leonuri, Radix Notoginseng, Hirudo, Ramulus Cinnamomi, Radix Salviae Miltiorrhizae, Rhizoma Atractylodis, Herba Pogostemonis, Herba Eupatorii crude drug to make up, make each efficacy of drugs produce synergism these drug regimens, thus recurrence that can the fast treating obesity.Wherein select Fructus Crataegi to be because its nature and flavor acid is sweet, tepor enters spleen, stomach, Liver Channel, have help digestion long-pending, dissipating blood stasis blood, taenifugal function is controlled meat Ji ， mass in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia, puerperal after-pains, lochiorrhea, children's's breast food is stagnated.Select Folium Nelumbinis to be because its nature and flavor are pained, flat, enter the heart, liver, spleen channel, clearing away summer-heat and eliminating dampness is arranged, sending up the lucid YANG, the function of hemostasis is controlled diarrhea due to summer heat and dampness, dizzy, the aqueous vapor edema, thunder-headache is spitted blood, epistaxis, metrorrhagia is had blood in stool, puerperal blood faints.It is sweet because of its nature and flavor, cold selecting Rhizoma Imperatae, enters lung, stomach, small intestine meridian, and removing heat from blood is arranged, hemostasis, and heat clearing away, the function of diuresis is controlled the calentura excessive thirst, spits blood, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.Select Rhizoma Phragmitis to be because its nature and flavor are sweet, cold, enter lung, the stomach warp has heat clearing away, promotes the production of body fluid, relieving restlessness, the function of preventing or arresting vomiting is controlled the calentura excessive thirst, and gastropyretic vomiting is dysphagic, regurgitation, consumptive lung disease, lung abscess, and separate Fugu ocellatus ichthyotoxin.Select Herba Leonuri to be because its nature and flavor are arduous, cool, enter pericardium, Liver Channel, invigorate blood circulation, blood stasis dispelling, regulating menstruation, the function of the water that disappears is controlled menoxenia, controls Lou difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria is rushed down blood, the carbuncle skin infection.Selecting Radix Notoginseng is that temperature enters liver, stomach, large intestine channel, and hemostasis is arranged because of its property sweet and slightly bitter taste, dissipating blood stasis, and detumescence, the function of analgesic therapy is controlled haematemesis, hemoptysis, epistaxis is had blood in stool, dysentery, metrorrhagia, mass in the abdomen, puerperal blood faints, retention of lochia falls and flutters blood stasis, traumatic hemorrhage, carbuncle pain.Select Hirudo to be because the salty hardship of its nature and flavor is flat, poisonous, enter liver, urinary bladder channel, removing blood stasis is arranged, removing blood stasis, the function of stimulating the menstrual flow is controlled blood-retention ， mass in the abdomen, gathers, women's amenorrhea, blood stasis becomes consumptive disease, injury from falling down, conjunctival congestion with ophthalmalgia, nebula.Selecting Ramulus Cinnamomi is that temperature enters bladder, the heart, lung meridian, and the diaphoresis expelling pathogenic factors from muscles is arranged because of its property acrid-sweet flavor, and the function of warming the meridian and promoting blood circulation is controlled exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.Select Radix Salviae Miltiorrhizae to be because its nature and flavor are bitter, tepor enters the heart, Liver Channel, and blood circulation and promoting silt is arranged, calming heart and tranquilizing mind, and evacuation of pus, the function of pain relieving is controlled angina cordis, menoxenia, dysmenorrhea, to close, metrorrhagia leukorrhagia ， mass in the abdomen gathers, abdominal pain due to blood stasis, arthralgia, palpitation with fear sleeplessness, malignant boil toxic swelling.Select Rhizoma Atractylodis to be because its nature and flavor are arduous, temperature enters spleen, stomach warp, and spleen invigorating is arranged, dampness, and resolving depression is warded off dirty function, control the wet tired spleen of containing, the asthenia drowsiness, gastral cavity painful abdominal mass abdominal distention, inappetence, vomiting is had loose bowels, dysentery, malaria, phlegm retention, edema, seasonal epidemic pathogens flu, anemofrigid-damp arthralgia, flaccidity of the lower limbs, nyctalopia.Select Herba Pogostemonis to be because its nature and flavor are hot, tepor enters lung, spleen, stomach warp, and fast gas is arranged, and in, ward off dirty, the function of damp eliminating, the heat-damp in summer that cures cold, cold and heat, headache, breast gastral cavity painful abdominal mass is vexed, vomiting is had loose bowels, malaria, dysentery, halitosis.Select Herba Eupatorii to be because its nature and flavor are hot, flat, enter spleen, stomach warp, clearing away summer-heat is arranged, ward off dirty, removing dampness, the function of regulating menstruation is controlled and is experienced heat-damp in summer, the cold and heat headache is accumulate in damp, the gastral cavity painful abdominal mass is not hungry, sweet taste in the mouth greasy fur, menoxenia.

The drug dose of the present invention's combination is also that the inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect in the following weight scope

Fructus Crataegi 25-35 gram Folium Nelumbinis 5-15 gram Rhizoma Imperatae 10-20 grams

Rhizoma Phragmitis 10-20 gram Herba Leonuri 25-35 gram Radix Notoginseng 6-15 grams

Hirudo 5-15 gram Ramulus Cinnamomi 1-5 gram Radix Salviae Miltiorrhizae 10-20 grams

Rhizoma Atractylodis 5-15 gram Herba Pogostemonis 8-17 gram Herba Eupatorii 10-15 grams

Preferable amount is

Fructus Crataegi 30 gram Folium Nelumbinis 9 gram Rhizoma Imperatae 15 grams

Rhizoma Phragmitis 15 gram Herba Leonuri 30 gram Radix Notoginseng 9 grams

Hirudo 9 gram Ramulus Cinnamomi 3 gram Radix Salviae Miltiorrhizae 15 grams

Rhizoma Atractylodis 9 gram Herba Pogostemonis 12 gram Herba Eupatorii 12 grams

The preparation method of medicine of the present invention is as follows

One, get the raw materials ready

1, Fructus Crataegi: choose clean impurity, the sieve enucleation;

2, Folium Nelumbinis: clean with water, cut off the base of a fruit and edge, shredding is dried;

3, Rhizoma Imperatae: choose clean impurity, clean, little profit, cutting is dried, the clean chip of winnowing with a dustpan;

4, Rhizoma Phragmitis: choose decontamination and root, cutting is dried;

5, Herba Leonuri: choose decontamination, clean, run through, cutting is dried;

6, Radix Notoginseng: choose most impurity, smash to pieces, grind or run through section into powder and dry;

7, Hirudo: clean, vexed soft, cutting is dried, grind into powder;

8, Ramulus Cinnamomi: water slightly soaks, and pulls out, and moistening is cut into slices to thoroughly, dries, and sieves anti-dandruff;

9, Radix Salviae Miltiorrhizae: choose clean impurity, remove rhizome, clean, pull out, run through rear section, dry;

10, Rhizoma Atractylodis: choose decontamination, with blister to seven, most probably saturating, pull out, run through rear section, dry;

11, Herba Pogostemonis: choose decontamination, remove undesirable root and old stem, first leaf is taken separately and put, the stem water runs through, and cutting is dried, then with leaf and even;

12, Herba Eupatorii: choose clean impurity, wash, pull out, slightly after the profit, remove undesirable root, cutting is dried.

Two, preparation

Fructus Crataegi, Folium Nelumbinis, Rhizoma Imperatae, Rhizoma Phragmitis, Herba Leonuri, Radix Notoginseng, Hirudo, Ramulus Cinnamomi, Radix Salviae Miltiorrhizae, Rhizoma Atractylodis, Herba Pogostemonis, the Herba Eupatorii crude drug of described weight are put into the container of boiling medicine, add 6 times of amounts of water, soak after 80 minutes, intense fire decocts boiling 20 minutes, used again slow fire boiling 30 minutes, filter to get decoction liquor, decoction liquor is poured in container, be divided into 3 doses.

Medicine of the present invention has diuretic, invigorate blood circulation, moisten lead, the function of depressed liver-energy dispersing and function of gallbladder promoting, the intestines and stomach coordinating, be used for the treatment of obesity, short treating period, instant effect, have no side effect.

The specific embodiment

Below further set forth the beneficial effect of medicine of the present invention by test example, these test examples have comprised animal toxicity test report and the clinical observation material of medicine of the present invention.

The animal toxicity test report of [test example 1] medicine of the present invention

Get 30 of rabbit, the male and female dual-purpose, body weight 2.0-2.5kg divides two groups, and 15 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 30ml/kg, and normal amount is 15ml/kg, and administering mode is the administration by gavage administration, and every day, secondary, serve on 17 days, observes the administration reaction every day, and result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.

The observations of [test example 2] Drug therapy obesity of the present invention

1, physical data

Accept obese patient's totally 200 examples for medical treatment, male's 130 examples wherein, women's 70 examples.

2, diagnostic criteria

Obesity is one group of common metabolism disease group.During more than consumption of calorie, waste heat is stored in body with fatty form when human body feed heat, and its amount surpasses the normal physiological requirement, and then develops into obesity when reaching certain value.Normal Male Adults fatty tissue weight approximately percentage of liveweight 15% ~ 18%, the women accounts for 20% ~ 25%.With age growth, the corresponding increase of body fat proportion.Because making be above standard body weight 20% or Body Mass Index ［ BMI=body weight (Kg)/(height) 2(m2) ］ of body weight, the increase of body fat is called obesity greater than 24.

3, Therapeutic Method

Select above-mentioned medicament, take to the patient, each serving with 1 dose, every day early, respectively take 1 evening, and 20 days is a course for the treatment of, takes continuously 3 courses for the treatment of.

4, efficacy assessment standard

Produce effects: the fat disappearance, body constitution recover normal, observe half a year without bounce-back person;

Take a turn for the better: obesity is obviously improved, and body constitution progressively strengthens;

Invalid: fat of changing, do not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

In above-mentioned treatment, with Drug therapy obese patient's 200 examples of the present invention, produce effects 180 examples as a result, obvious effective rate is 90%, 16 examples that take a turn for the better, improvement rate is 8%, invalid 4 examples, total effective rate is 98%.

Claims (3)

1. treat fat medicine for one kind, it is characterized in that: it is to be made by the crude drug in following weight range:

Fructus Crataegi 25-35 gram Folium Nelumbinis 5-15 gram Rhizoma Imperatae 10-20 grams

Rhizoma Phragmitis 10-20 gram Herba Leonuri 25-35 gram Radix Notoginseng 6-15 grams

Hirudo 5-15 gram Ramulus Cinnamomi 1-5 gram Radix Salviae Miltiorrhizae 10-20 grams

Rhizoma Atractylodis 5-15 gram Herba Pogostemonis 8-17 gram Herba Eupatorii 10-15 grams.

2. treat according to claim 1 fat medicine, wherein the consumption of each crude drug is:

Fructus Crataegi 30 gram Folium Nelumbinis 9 gram Rhizoma Imperatae 15 grams

Rhizoma Phragmitis 15 gram Herba Leonuri 30 gram Radix Notoginseng 9 grams

Hirudo 9 gram Ramulus Cinnamomi 3 gram Radix Salviae Miltiorrhizae 15 grams

Rhizoma Atractylodis 9 gram Herba Pogostemonis 12 gram Herba Eupatorii 12 grams.

3. the preparation method of described medicine according to claim 1 and 2, it comprises the following steps:

(1) get the raw materials ready

(1) Fructus Crataegi: choose clean impurity, the sieve enucleation;

(2) Folium Nelumbinis: clean with water, cut off the base of a fruit and edge, shredding is dried;

(3) Rhizoma Imperatae: choose clean impurity, clean, little profit, cutting is dried, the clean chip of winnowing with a dustpan;

(4) Rhizoma Phragmitis: choose decontamination and root, cutting is dried;

(5) Herba Leonuri: choose decontamination, clean, run through, cutting is dried;

(6) Radix Notoginseng: choose most impurity, smash to pieces, grind or run through section into powder and dry;

(7) Hirudo: clean, vexed soft, cutting is dried, grind into powder;

(8) Ramulus Cinnamomi: water slightly soaks, and pulls out, and moistening is cut into slices to thoroughly, dries, and sieves anti-dandruff;

(9) Radix Salviae Miltiorrhizae: choose clean impurity, remove rhizome, clean, pull out, run through rear section, dry;

(10) Rhizoma Atractylodis: choose decontamination, with blister to seven, most probably saturating, pull out, run through rear section, dry;

(11) Herba Pogostemonis: choose decontamination, remove undesirable root and old stem, first leaf is taken separately and put, the stem water runs through, and cutting is dried, then with leaf and even;

(12) Herba Eupatorii: choose clean impurity, wash, pull out, slightly after the profit, remove undesirable root, cutting is dried;

(2) preparation

Fructus Crataegi, Folium Nelumbinis, Rhizoma Imperatae, Rhizoma Phragmitis, Herba Leonuri, Radix Notoginseng, Hirudo, Ramulus Cinnamomi, Radix Salviae Miltiorrhizae, Rhizoma Atractylodis, Herba Pogostemonis, the Herba Eupatorii crude drug of described weight are put into the container of boiling medicine, add 6 times of amounts of water, soak after 80 minutes, intense fire decocts boiling 20 minutes, used again slow fire boiling 30 minutes, filter to get decoction liquor, decoction liquor is poured in container, be divided into 3 doses.