CN102038889B - Traditional Chinese medicament for treating rheumatic heart disease - Google Patents

Abstract

The invention belongs to the field of traditional Chinese medicament, and in particular discloses a traditional Chinese medicament for treating rheumatic heart disease. The traditional Chinese medicament consists of radix polygonati officinalis, rohdea japonica, raw rehmanniae, motherwort, bamboo leaves, turpentine, coix seeds, eggplant root, safflower, peach kernels, Chinese date, weeping forsythiae capsule, Chinese magnoliavine fruit, mulberry twig, roasted liquorice, pear leaves and flower of silktree albizzia serving as active components in certain parts by weight. The traditional Chinese medicament has simplicity in preparation, good absorption effect, remarkable curative effect, no side effect and high safety, and is advantageous to lighten symptom of patients in time.

Description

The Chinese medicine of treatment rheumatic heart disease

(1) technical field

The invention belongs to the field of Chinese medicines, particularly a kind of Chinese medicine for the treatment of rheumatic heart disease.

(2) background technology

Rheumatic heart disease is a kind of common heart disease, this disease is to involve the caused chronic cardiac valve infringement of endocardium, cardiac muscle or pericardium by rheumatism, forms the narrow or incompetence of valve orifice, causes hemodynamic change, increase the weight of the heart burden, impel heart failure.This sick fundamental symptoms is cardiopalmus, tachypnea, dyspnea, chest pain, dizziness, edema, cough, heart miasma etc.

At present, the method for the treatment of rheumatic heart disease both at home and abroad is more, and as the western medicine method, medicine commonly used has sorbitrate, nifedipine, atenolol, captopril etc.; As the treatment by Chinese herbs method, medicine commonly used has GUIPI WAN, zhigancao decoction, Chinese goldthread colla corii asini decoction etc.But, be difficult to the effect that reaches satisfied at aspects such as cure rate, treatment means, medical expenses.

(3) summary of the invention

The present invention provides a kind of Chinese medicine of preparing treatment rheumatic heart disease simple, evident in efficacy in order to remedy the deficiencies in the prior art.

The present invention is achieved through the following technical solutions:

A kind of Chinese medicine for the treatment of rheumatic heart disease, its active component is made up of the raw material of following parts by weight:

6～12 parts of Rhizoma Polygonati Odorati, 3～9 parts of Rohdea japonica Roth, 9～15 parts of Radix Rehmanniae, 9～15 parts of Herba Leonuris, 6～12 parts on Folium Bambusae, 9～15 parts of Lignum Pini Nodis, 10～20 parts of Semen Coiciss, 9～15 parts of Radix Solani Melongenae, 3～9 parts on Flos Carthami, 6～10 parts in Semen Persicae, 9～15 parts in Fructus Jujubae, 6～12 parts of Fructus Forsythiaes, 2～6 parts of Fructus Schisandrae Chinensis, 10～20 parts of Ramulus Moris, 6～10 parts of Radix Glycyrrhizae Preparatas, 9～15 parts of Folium pyri, 3～9 parts of Flos Albiziaes.

The weight proportion of its preferred each activated feedstock is:

9 parts of Rhizoma Polygonati Odorati, 6 parts of Rohdea japonica Roth, 12 parts of Radix Rehmanniae, 12 parts of Herba Leonuris, 9 parts on Folium Bambusae, 12 parts of Lignum Pini Nodis, 15 parts of Semen Coiciss, 12 parts of Radix Solani Melongenae, 6 parts on Flos Carthami, 8 parts in Semen Persicae, 12 parts in Fructus Jujubae, 9 parts of Fructus Forsythiaes, 4 parts of Fructus Schisandrae Chinensis, 15 parts of Ramulus Moris, 8 parts of Radix Glycyrrhizae Preparatas, 12 parts of Folium pyri, 6 parts of Flos Albiziaes.

Described Chinese medicine is powder or pill.After various raw materials are cleaned up, beat powder and mix, make powder or pill, quantitatively take.

The pharmaceutical characteristic of each active component that the present invention adopts is:

Rhizoma Polygonati Odorati: nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid.Cure mainly cough caused by dryness, chronic cough, calentura is cloudy hinders, and dry throat and mouth is quenched one's thirst, and deficiency of YIN diseases caused by exogenous pathogenic factor are dizzy dizzy, muscle arteries and veins spasm and pain;

Rohdea japonica Roth: heat-clearing and toxic substances removing, heart tonifying diuresis.Cure mainly laryngopharynx swelling and pain, diphtheria, mumps, sore swollen toxin, acute mastitis, snake bite and insect sting, heart failure, edema, tympanites, spitting of blood is spitted blood;

Radix Rehmanniae: have another name called Radix Rehmanniae, clearing away heat from blood, easy cloudy blood, promoting blood circulation.Cure mainly epidemic febrile disease heating, haematemesis, epistaxis, metrorrhagia, the hematuria due to the jaundice, heat in blood, have blood in stool, quench one's thirst hectic fever due to YIN-deficiency consumptive fever, amenorrhea, puerperal abdonimal pain, numbness flaccidity, traumatic injury;

Herba Leonuri: promoting blood flow to regulate menstruation, inducing diuresis to remove edema, heat-clearing and toxic substances removing.Cure mainly menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection;

Folium Bambusae: clearing heat and relieving fidgetness, promote the production of body fluid diuresis.Cure mainly the calentura excessive thirst, pediatric epilepsy scared, cough with dyspnea is told nosebleed, oliguria with reddish urine, erosion of the oral mucosa is given birth to skin ulcer;

Lignum Pini Nodi: dispel the wind, dampness, Shujin, active, pain relieving.Cure mainly anemofrigid-damp arthralgia, the severe and migratory arthralgia pain, the convulsion contraction is anxious, and foot numbness flaccidity is soft, the arthroncus of knee, traumatic pain;

Semen Coicis: dampness removing spleen invigorating, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus.Cure mainly edema, beriberi, dribbling urination, damp-warm diseases is had loose bowels, leukorrhagia, rheumatic arthralgia, the contracture of muscle arteries and veins, lung abscess, acute appendicitis, verruca plana;

Radix Solani Melongenae: expelling wind and removing dampness, hemostasis dissipating blood stasis.Cure mainly chronic dysentery, have blood in stool, hemorrhoidal bleeding, rheumatic arthralgia, beriberi, women's pudendal pruritus, skin pruritus, chilblain;

Flos Carthami: promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.Cure mainly the blood stasis amenorrhea, dysmenorrhea, postpartum stagnation stomachache, obstruction of qi in the chest and cardialgia ， lumps in the chest and abdomen, traumatic injury, arthralgia, apoplectic hemiplegia, macule;

Semen Persicae: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.Cure mainly dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation;

Fructus Jujubae: tonifying the spleen and stomach, replenishing QI and blood, tranquilizing mind transfers battalion to defend, and the property of medicine.Cure mainly weakness of the spleen and stomach, insufficiency of vital energy and blood, anorexia and loose stool, fatigue and weakness, palpitation and insomnia, woman hysteria, disharmony of nutrient QI with defensive QI;

Fructus Forsythiae: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Cure mainly anemopyretic cold, damp disease, pyretic stranguria urine retention, carbuncle, toxic swelling, scrofula, goiter, sore throat;

Fructus Schisandrae Chinensis: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, mind tranquilizing and the heart calming.Cure mainly the chronic cough dyspnea due to deficiency, emission, frequent urination and enuresis, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, palpitation and insomnia;

Ramulus Mori: wind-damp dispelling, the meridian dredging, row aqueous vapor.Cure mainly rheumatic arthralgia, apoplexy and hemiplegia, edema beriberi, human body pruritus due to wind pathogen;

Radix Glycyrrhizae Preparata: and middle emergency, lung moistening, detoxifcation, coordinating the actions of various ingredients in a prescription.Cure mainly weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough;

Folium pyri: diuretic, detoxifcation.Cure mainly edema, dysuria, sore, toadstool poisons;

Flos Albiziae: Shu Yu calms the nerves, and regulates the flow of vital energy, and makes eye bright, and is active.Cure mainly melancholy insomnia, irritability, forgetful, uncomfortable in chest indigestion and loss of appetite, wind-fire ophthalmic, blurring of vision, lumbago, traumatic pain.

In the prescription, Rohdea japonica Roth, Folium Bambusae, Fructus Forsythiae, Folium pyri are mainly used in heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, heart tonifying diuresis; Add and join Lignum Pini Nodi, Semen Coicis, Radix Solani Melongenae, Ramulus Mori, be mainly used in dispeiling pathogenic wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, hemostasis dissipating blood stasis; Join Radix Rehmanniae, Herba Leonuri, Flos Carthami, Semen Persicae again, be used for that clearing away heat from blood, Yiyang are promoted blood circulation, promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing; Join Rhizoma Polygonati Odorati, Fructus Jujubae, Fructus Schisandrae Chinensis, Flos Albiziae again, be used for nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, warming middle-JIAO warming the kidney, astringent or styptic treatment for spontaneous sweating, the tranquilizing by nourishing the heart of convergence; Add with Radix Glycyrrhizae Preparata at last and be used for heat-clearing and toxic substances removing, alleviate pain relieving, coordinating the actions of various ingredients in a prescription, the toxicity of cushion and strong.

Clinical observation:

(1) clinical data

The inventor carries out clinical observation treatment to 139 routine rheumatic heart patients from 2007 so far, wherein male 61 examples, and women 78 examples, the age is between 20～68 years old.

(2) Therapeutic Method

Oral, three times on the one, each 5～10g, one after each meal.Calculate treatment time according to the conditions of patients weight, patients with mild was taken about 30 days, and the severe case serve on 60 days and can fully recover.

(3) curative effect determinate standard

Cure: symptom all disappears; Main physics and chemistry detects index and is normally.

Produce effects: symptomatology is eliminated or cardinal symptom is eliminated; It is normal substantially that physics and chemistry detects index.

Effectively: cardinal symptom disappears substantially; Main physics and chemistry detects index and makes moderate progress.

Invalid: main physics and chemistry detects index and the preceding no change of treatment.

(4) clinical effectiveness

Clinical cure 113 examples (81.30%), produce effects 14 examples (10.07%), effective 10 examples (7.19%), invalid 2 examples (1.44%), total effective rate is 98.56%.

The present invention prepares simply, and good absorbing effect is evident in efficacy, has no side effect, and is safe, helps sufferer and in time alleviates condition of illness.

(4) specific embodiment

Embodiment 1:

Get Rhizoma Polygonati Odorati 6g, Rohdea japonica Roth 3g, Radix Rehmanniae 9g, Herba Leonuri 9g, Folium Bambusae 6g, Lignum Pini Nodi 9g, Semen Coicis 10g, Radix Solani Melongenae 9g, Flos Carthami 3g, Semen Persicae 6g, Fructus Jujubae 9g, Fructus Forsythiae 6g, Fructus Schisandrae Chinensis 2g, Ramulus Mori 10g, Radix Glycyrrhizae Preparata 6g, Folium pyri 9g, Flos Albiziae 3g, above-mentioned raw materials is cleaned up, beating powder mixes, make powder or pill, quantitatively take.

Usage and dosage: oral, three times on the one, each 5～10g, one after each meal.

Embodiment 2:

Get Rhizoma Polygonati Odorati 12g, Rohdea japonica Roth 9g, Radix Rehmanniae 15g, Herba Leonuri 15g, Folium Bambusae 12g, Lignum Pini Nodi 15g, Semen Coicis 20g, Radix Solani Melongenae 15g, Flos Carthami 9g, Semen Persicae 10g, Fructus Jujubae 15g, Fructus Forsythiae 12g, Fructus Schisandrae Chinensis 6g, Ramulus Mori 20g, Radix Glycyrrhizae Preparata 10g, Folium pyri 15g, Flos Albiziae 9g, above-mentioned raw materials is cleaned up, beating powder mixes, make powder or pill, quantitatively take.

Usage and dosage: oral, three times on the one, each 5～10g, one after each meal.

Embodiment 3:

Get Rhizoma Polygonati Odorati 9g, Rohdea japonica Roth 6g, Radix Rehmanniae 12g, Herba Leonuri 12g, Folium Bambusae 9g, Lignum Pini Nodi 12g, Semen Coicis 15g, Radix Solani Melongenae 12g, Flos Carthami 6g, Semen Persicae 8g, Fructus Jujubae 12g, Fructus Forsythiae 9g, Fructus Schisandrae Chinensis 4g, Ramulus Mori 15g, Radix Glycyrrhizae Preparata 8g, Folium pyri 12g, Flos Albiziae 6g, above-mentioned raw materials is cleaned up, beating powder mixes, make powder or pill, quantitatively take.

Usage and dosage: oral, three times on the one, each 5～10g, one after each meal.

Claims (3)

1. a Chinese medicine for the treatment of rheumatic heart disease is characterized by, and its active component is made up of the raw material of following parts by weight:

6～12 parts of Rhizoma Polygonati Odorati, 3～9 parts of Rohdea japonica Roth, 9～15 parts of Radix Rehmanniae, 9～15 parts of Herba Leonuris, 6～12 parts on Folium Bambusae, 9～15 parts of Lignum Pini Nodis, 10～20 parts of Semen Coiciss, 9～15 parts of Radix Solani Melongenae, 3～9 parts on Flos Carthami, 6～10 parts in Semen Persicae, 9～15 parts in Fructus Jujubae, 6～12 parts of Fructus Forsythiaes, 2～6 parts of Fructus Schisandrae Chinensis, 10～20 parts of Ramulus Moris, 6～10 parts of Radix Glycyrrhizae Preparatas, 9～15 parts of Folium pyri, 3～9 parts of Flos Albiziaes.

2. the Chinese medicine of treatment rheumatic heart disease according to claim 1 is characterized by, and its active component is made up of the raw material of following parts by weight:

9 parts of Rhizoma Polygonati Odorati, 6 parts of Rohdea japonica Roth, 12 parts of Radix Rehmanniae, 12 parts of Herba Leonuris, 9 parts on Folium Bambusae, 12 parts of Lignum Pini Nodis, 15 parts of Semen Coiciss, 12 parts of Radix Solani Melongenae, 6 parts on Flos Carthami, 8 parts in Semen Persicae, 12 parts in Fructus Jujubae, 9 parts of Fructus Forsythiaes, 4 parts of Fructus Schisandrae Chinensis, 15 parts of Ramulus Moris, 8 parts of Radix Glycyrrhizae Preparatas, 12 parts of Folium pyri, 6 parts of Flos Albiziaes.

3. the Chinese medicine of treatment rheumatic heart disease according to claim 1 and 2 is characterized in that: described Chinese medicine is powder or pill.