CN103108643B - 包含过氧化物、醇和螯合剂的抗菌剂 - Google Patents

包含过氧化物、醇和螯合剂的抗菌剂 Download PDF

Info

Publication number
CN103108643B
CN103108643B CN201180006632.3A CN201180006632A CN103108643B CN 103108643 B CN103108643 B CN 103108643B CN 201180006632 A CN201180006632 A CN 201180006632A CN 103108643 B CN103108643 B CN 103108643B
Authority
CN
China
Prior art keywords
present application
antibacterial
peroxide
biofilm
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201180006632.3A
Other languages
English (en)
Chinese (zh)
Other versions
CN103108643A (zh
Inventor
P·O·滕尼肯
L·M·菲普斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hyprotek Inc
Original Assignee
Hyprotek Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hyprotek Inc filed Critical Hyprotek Inc
Publication of CN103108643A publication Critical patent/CN103108643A/zh
Application granted granted Critical
Publication of CN103108643B publication Critical patent/CN103108643B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/02—Acyclic compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
CN201180006632.3A 2010-01-22 2011-01-21 包含过氧化物、醇和螯合剂的抗菌剂 Expired - Fee Related CN103108643B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US29760910P 2010-01-22 2010-01-22
US61/297,609 2010-01-22
US41237510P 2010-11-10 2010-11-10
US61/412,375 2010-11-10
PCT/US2011/022150 WO2011091322A2 (en) 2010-01-22 2011-01-21 Antimicrobial agents and methods of use

Publications (2)

Publication Number Publication Date
CN103108643A CN103108643A (zh) 2013-05-15
CN103108643B true CN103108643B (zh) 2016-10-26

Family

ID=44247755

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180006632.3A Expired - Fee Related CN103108643B (zh) 2010-01-22 2011-01-21 包含过氧化物、醇和螯合剂的抗菌剂

Country Status (12)

Country Link
US (3) US8846008B2 (enExample)
EP (1) EP2525803B1 (enExample)
JP (2) JP5866298B2 (enExample)
KR (1) KR101785130B1 (enExample)
CN (1) CN103108643B (enExample)
AU (1) AU2011207398B2 (enExample)
BR (1) BR112012018170B8 (enExample)
CA (1) CA2786880C (enExample)
MX (1) MX2012008482A (enExample)
RU (1) RU2570387C2 (enExample)
SG (1) SG182452A1 (enExample)
WO (1) WO2011091322A2 (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9192449B2 (en) 2007-04-02 2015-11-24 C. R. Bard, Inc. Medical component scrubbing device with detachable cap
US8336152B2 (en) 2007-04-02 2012-12-25 C. R. Bard, Inc. Insert for a microbial scrubbing device
BRPI0811530B1 (pt) 2007-05-14 2019-01-02 Research Foundation Of State Univ Of New York composição compreendendo indutor(es) de resposta fisiológica à dispersão ácido decanóico, superfície, solução, método ex vivo de tratamento ou inibição da formação de um biofilme sobre uma superfície
US8778387B2 (en) * 2009-09-02 2014-07-15 Hyprotek, Inc. Antimicrobial medical dressings and protecting wounds and catheter sites
SG182452A1 (en) 2010-01-22 2012-08-30 Hyprotek Inc Antimicrobial agent comprising peroxide, alcohol and chelating agent
WO2013042140A2 (en) * 2011-09-23 2013-03-28 Manu Chaudhary Non antibiotic,non peptide compounds for antibiotic efficacy & safety enhancement
MX367716B (es) 2011-11-28 2019-09-03 Hyprotek Inc Dispositivos de cateter y tecnicas.
US9192443B2 (en) 2012-02-06 2015-11-24 Hyprotek, Inc. Combined cap applicators
WO2014087241A2 (en) * 2012-12-05 2014-06-12 Institut Pasteur Methods of detecting biofilms from the palmitoylation of lipopolysaccharides
US10203329B2 (en) 2013-09-12 2019-02-12 The Johns Hopkins University Biofilm formation to define risk for colon cancer
CN104146994A (zh) * 2014-06-10 2014-11-19 苏州普洛赛医药科技有限公司 一种用于化学及高温灼伤的应急保护液剂及其制备方法
US20180044628A1 (en) * 2015-03-13 2018-02-15 The Regents Of The University Of California Method for Biofilm Control and Treatment
US11541105B2 (en) 2018-06-01 2023-01-03 The Research Foundation For The State University Of New York Compositions and methods for disrupting biofilm formation and maintenance
PT115056B (pt) * 2018-10-04 2021-12-10 Hovione Farm Sa Formas amorfas de agentes quelantes e seus métodos de preparação
CN112955009B (zh) * 2018-10-31 2022-10-25 富士胶片株式会社 组合物、喷雾器及擦拭布
CN113382755A (zh) * 2019-01-28 2021-09-10 希普罗特克有限公司 具有促凝血特性、免疫调节特性和组织再生特性的抗微生物组合物
CN110006724B (zh) * 2019-04-17 2021-06-04 郑州安图生物工程股份有限公司 采用巴氏和革兰氏染色方法检测滴虫用试剂
CN110024781A (zh) * 2019-05-23 2019-07-19 昆明野水生物科技有限公司 一种在常温下能迅速杀灭芽孢的制剂及其应用
BR112021024716A2 (pt) * 2019-06-19 2022-02-08 QBiotics Pty Ltd Ruptura de biofilme
CN111264558A (zh) * 2020-04-07 2020-06-12 河南省奥林特药业有限公司 一种抑制乙醇挥发的免洗凝胶消毒剂及其制备工艺
KR102340910B1 (ko) * 2020-07-21 2021-12-16 이난희 거품 촉진 욕실용 세정제 및 이의 제조방법
JP2022043957A (ja) * 2020-09-04 2022-03-16 中 木田 強力な殺芽胞能力を発揮するスチームクリーナー
WO2024173302A1 (en) 2023-02-15 2024-08-22 Hyprotek, Inc. Closed sterile medication mixing and/or administration system with disinfection options

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004108091A2 (en) * 2003-06-06 2004-12-16 Board Of Regents, The University Of Texas System Antimicrobial flush solutions
WO2005025486A2 (en) * 2003-09-13 2005-03-24 Boots Healthcare International Limited Skincare compositions comprising salicyclic acid
CN1711845A (zh) * 2004-06-25 2005-12-28 殷生章 一种可杀灭非典肺炎冠状病毒的消毒剂
WO2009076718A1 (en) * 2007-12-17 2009-06-25 Novapharm Research (Australia) Pty Ltd Viricidal composition

Family Cites Families (100)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB350384A (en) 1929-03-04 1931-06-04 John Barnard Kirsch Dressing for wounds ready for use
US4188234A (en) 1965-08-24 1980-02-12 Plains Chemical Development Co. Chelation
US3607760A (en) 1969-06-09 1971-09-21 Edna M Mcintyre Cleaning composition for pet stains
US3860348A (en) 1973-06-06 1975-01-14 Schick Inc Applicator package for fluid products
US4291697A (en) 1980-04-18 1981-09-29 Stephen Georgevich Cleaning and application device for medical purposes
WO1985003275A1 (en) 1984-01-23 1985-08-01 Laipply Thomas C Alcohol wipe and methods
US5046608A (en) 1981-10-19 1991-09-10 Laipply Thomas C Combined fluid storage container and applicator device and method
US4440207A (en) 1982-05-14 1984-04-03 Baxter Travenol Laboratories, Inc. Antibacterial protective cap for connectors
US4564010A (en) 1984-04-18 1986-01-14 Daubert Coated Products Inc. Pressure sensitive adhesive film for medical use
JPS6274364A (ja) 1985-09-27 1987-04-06 株式会社 ニツシヨ− 医療用具
GB8622698D0 (en) 1986-09-20 1986-10-29 Smith & Nephew Ass Dispenser
US4830856A (en) 1987-01-27 1989-05-16 Peppers James M Chelation product
US4811847A (en) 1988-03-14 1989-03-14 Reif Thomas H Urinary catheter package
US4954239A (en) 1988-04-15 1990-09-04 Mueller Louis H Prefilled catheter tip syringe kit
US5438984A (en) 1988-09-08 1995-08-08 Sudor Partners Apparatus and method for the collection of analytes on a dermal patch
US5041264A (en) 1988-10-03 1991-08-20 Williams Robert M Method and apparatus for disinfecting objects
US5171523A (en) 1988-10-03 1992-12-15 Williams Robert M Method and apparatus for disinfecting objects
US4893956A (en) 1988-11-18 1990-01-16 Blistex Inc. Packaging for medicaments
US5015228A (en) 1989-06-05 1991-05-14 Eastman Kodak Company Sterilizing dressing device and method for skin puncture
EP0544778A1 (en) 1990-09-17 1993-06-09 Medipro Sciences Limited Bilayer wound dressing
DE69229122T2 (de) 1991-11-06 2000-01-05 Bioderm, Inc. 0kklusiver wundverband sowie vorrichtung zum anbringen
US5222600A (en) 1992-07-28 1993-06-29 Stoddard James T Autoclave pouch
CA2151144A1 (en) 1992-12-07 1994-06-23 Masaru Saita Diagnostic patch and method for diagnosis using the same
ATE232072T1 (de) 1993-05-04 2003-02-15 Lisa Fernandez Geng Wundverband
US5454798A (en) 1993-05-14 1995-10-03 Mentor Corporation Disposable urine bag
AU7256194A (en) 1993-07-06 1995-02-06 Leo J. Utecht Personal protection apparatus
DE4332093C2 (de) 1993-09-22 1995-07-13 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit dem Wirkstoff Acetylsalicylsäure und Verfahren zu seiner Herstellung
US5731275A (en) * 1994-04-05 1998-03-24 Universite De Montreal Synergistic detergent and disinfectant combinations for decontaminating biofilm-coated surfaces
GB9411429D0 (en) 1994-06-08 1994-07-27 Seton Healthcare Group Plc Wound dressings
US5556375A (en) 1994-06-16 1996-09-17 Hercules Incorporated Wound dressing having a fenestrated base layer
US5569207A (en) 1994-10-13 1996-10-29 Quinton Instrument Company Hydrocolloid dressing
US5554135A (en) 1995-02-17 1996-09-10 Menyhay; Steve Z. Sterile medical injection port and cover method and apparatus
WO1996032142A1 (en) 1995-04-12 1996-10-17 Hopp Robert B Skin patch for use in contact immunotherapy
MX9601936A (es) 1995-07-07 1997-01-31 Becton Dickinson Co Una bandeja mejorada para la preparacion de la piel para uso en procedimientos quirurgicos.
US5976117A (en) 1996-09-25 1999-11-02 3M Innovative Properties Company Wound dressing
JPH10110268A (ja) 1996-10-03 1998-04-28 Nissin Electric Co Ltd 医療用被覆材
US20030007939A1 (en) * 1998-07-31 2003-01-09 Howard Murad Pharmaceutical compositions and methods for managing dermatological conditions
US6071541A (en) 1998-07-31 2000-06-06 Murad; Howard Pharmaceutical compositions and methods for managing skin conditions
US6168800B1 (en) 1998-08-20 2001-01-02 Medwrap Corporation Antimcrobial multi-layer island dressing
AU764340B2 (en) * 1998-11-06 2003-08-14 Universite De Montreal Improved bactericidal and non-bactericidal solutions for removing biofilms
FR2804601B1 (fr) 2000-02-04 2002-04-26 3X Engineering Dispositif d'application de principes actifs utilisables dans le domaine pharmaceutique ou cosmetique
US6455066B1 (en) 2000-03-10 2002-09-24 Epicept Corporation Intradermal-penetration agents for topical local anesthetic administration
CA2411950A1 (en) 2000-06-13 2002-12-09 Hisamitsu Pharmaceutical Co., Inc. Patch
US7482021B1 (en) 2001-05-11 2009-01-27 Tison Kelley H Two-sided wipe for cleaning and drying a skin surface
US8541472B2 (en) * 2001-12-05 2013-09-24 Aseptica, Inc. Antiseptic compositions, methods and systems
GB2382775B (en) 2001-12-06 2005-05-25 Johnson & Johnson Medical Ltd Controlled release therapeutic wound dressings
JP2004049540A (ja) 2002-07-19 2004-02-19 Chisso Corp 抗菌性粘着フィルム及びそれを用いた救急絆創膏
EP1393710A1 (en) * 2002-08-21 2004-03-03 The Procter & Gamble Company A method of applying an oral composition
US9597067B2 (en) 2002-10-04 2017-03-21 Ethicon, Inc. Packaged antimicrobial medical device and method of preparing same
US8112973B2 (en) 2002-10-04 2012-02-14 Ethicon, Inc. Method of making a packaged antimicrobial suture
US8100872B2 (en) 2002-10-23 2012-01-24 Tyco Healthcare Group Lp Medical dressing containing antimicrobial agent
EP1589902A1 (en) 2003-01-27 2005-11-02 Medtronic Vascular Connaught Improved packaging for stent delivery systems
US20060142684A1 (en) 2003-04-11 2006-06-29 Shanbrom Technologies, Llc Oxygen releasing material
US7282186B2 (en) 2003-06-20 2007-10-16 Lake Jr Robert F Decontamination device
US20040261196A1 (en) 2003-06-27 2004-12-30 The Procter & Gamble Company Fabric care compositions for lipophilic fluid systems incorporating an antimicrobial agent
DE10331192A1 (de) 2003-07-10 2005-02-03 Paul Hartmann Ag Hautfreundliches Einwegprodukt
US20050034731A1 (en) 2003-08-13 2005-02-17 Rousseau Robert A. Surgical wound closure device
JP4476593B2 (ja) 2003-10-16 2010-06-09 日東電工株式会社 医療用粘着性抗菌シート
CA2545157A1 (en) 2003-11-11 2005-05-19 Veckis Industries Ltd. Disinfecting composition and methods of making and using same
GB2408207A (en) 2003-11-24 2005-05-25 Johnson & Johnson Medical Ltd Wound dressing for the controlled release of therapeutic agents comprising also an inhibitor of a protease enzyme & a linker group cleavable by such an enzyme
US20050129897A1 (en) 2003-12-11 2005-06-16 Kimberly-Clark Worldwide, Inc. Disposable scrubbing product
EP1699397A4 (en) 2003-12-23 2012-02-15 Hemcon Inc TISSUE ASSEMBLY, SYSTEMS AND METHODS FROM HYDROPHILIC POLYMER SPONGES, SUCH AS CHITOSAN
US7204368B2 (en) 2003-12-29 2007-04-17 Cheaure Sarah F Resealable package
JP2005350571A (ja) 2004-06-10 2005-12-22 Sekisui Chem Co Ltd 熱可塑性樹脂発泡体シート及び熱可塑性樹脂発泡体シートの製造方法
WO2005089341A2 (en) 2004-03-16 2005-09-29 Bull Brian S Method and device for coronary artery bypass
US7478962B2 (en) 2004-05-26 2009-01-20 L'oreal Device for packaging and application of a product
US20050281890A1 (en) 2004-06-18 2005-12-22 San Chandan K Methods and compositions for wound healing
RU2393876C2 (ru) 2004-09-17 2010-07-10 Дэвид М. ДИКСОН Перевязочный материал для ухода за раной и способ его использования
US7506760B2 (en) 2005-01-10 2009-03-24 Grossman Victor A Packaging and dispensers for adhesive backed elements
EP1887863A2 (en) 2005-02-07 2008-02-20 SiShield Technologies Methods and compositions for biocidal treatments
WO2006089139A2 (en) 2005-02-15 2006-08-24 Lab39, Llc Oral care cleaning compositions and methods
GB0525504D0 (en) 2005-12-14 2006-01-25 Bristol Myers Squibb Co Antimicrobial composition
US20070179373A1 (en) 2005-12-22 2007-08-02 Provex Technologies, Llc. Integrated patch and assay device with visual detection means
US7799965B2 (en) 2006-04-11 2010-09-21 Tyco Healthcare Group Lp Wound dressings with anti-microbial and zinc-containing agents
US8162899B2 (en) 2006-05-18 2012-04-24 Hyprotek, Inc. Intravascular line and port cleaning methods, methods of administering an agent intravascularly, methods of obtaining/testing blood, and devices for performing such methods
EP2308543B1 (en) 2006-06-08 2013-05-29 Hollister Incorporated Catheter product package
CA2656491C (en) * 2006-07-06 2014-11-18 Centennial Ventures B.V. Broad spectrum and skin friendly disinfecting composition
GB0614278D0 (en) 2006-07-19 2006-08-30 Insense Ltd Hydrogen peroxide delivery system
US7780794B2 (en) 2006-07-21 2010-08-24 Ivera Medical Corporation Medical implement cleaning device
US8403898B2 (en) 2006-11-21 2013-03-26 Mark R. Moore Apparatus and method for deploying a surgical preparation
US8647326B2 (en) 2007-01-16 2014-02-11 Catheter Connections, Inc. System for cleaning luer connectors
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
US8336152B2 (en) 2007-04-02 2012-12-25 C. R. Bard, Inc. Insert for a microbial scrubbing device
US8065773B2 (en) 2007-04-02 2011-11-29 Bard Access Systems, Inc. Microbial scrub brush
WO2009005814A2 (en) 2007-07-03 2009-01-08 Marchitto Kevin S Drug-delivery patch comprising a dissolvable layer and uses thereof
US20090028750A1 (en) 2007-07-23 2009-01-29 Ryan Dana Wm Cleaning and Disinfection Swabbing Device for Needle-Free Intravenous (IV) Connectors
US20090036541A1 (en) 2007-08-02 2009-02-05 Donald David Mardis Applicator and chemical combination for better topical anesthesia
US8388894B2 (en) 2008-03-20 2013-03-05 Psi Medical Catheter Care, Llc Apparatus and method for sterilizing a tubular medical line port
WO2009136957A1 (en) 2008-05-06 2009-11-12 Ferlic Michael J Universal sterilizing tool
US8777504B2 (en) 2008-07-03 2014-07-15 Retractable Technologies, Inc. Cleaning tool
US20100030170A1 (en) 2008-08-01 2010-02-04 Keith Alan Keller Absorptive Pad
US8486004B1 (en) 2009-07-02 2013-07-16 Centurion Medical Products Corporation Dressing having integral antimicrobial
WO2011019132A1 (ko) 2009-08-14 2011-02-17 중앙대학교 산학협력단 도전성 접착제, 이를 이용한 반도체의 실장방법 및 웨이퍼 레벨 패키지
US20110184382A1 (en) 2009-08-20 2011-07-28 Cady Timothy B Multi-purpose articles for sanitizing and capping luer access valves
US8778387B2 (en) 2009-09-02 2014-07-15 Hyprotek, Inc. Antimicrobial medical dressings and protecting wounds and catheter sites
SG182452A1 (en) 2010-01-22 2012-08-30 Hyprotek Inc Antimicrobial agent comprising peroxide, alcohol and chelating agent
US8496625B2 (en) 2010-05-26 2013-07-30 Nxstage Medical, Inc. Safe needle methods, apparatus, and systems
US20110314619A1 (en) 2010-06-23 2011-12-29 Medical Components, Inc. Cleaner for Medical Device
MX367716B (es) 2011-11-28 2019-09-03 Hyprotek Inc Dispositivos de cateter y tecnicas.
DK2882433T3 (da) * 2012-08-08 2019-05-27 Univ Texas Antimikrobielle sammensætninger omfattende glycerylnitrater

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004108091A2 (en) * 2003-06-06 2004-12-16 Board Of Regents, The University Of Texas System Antimicrobial flush solutions
WO2005025486A2 (en) * 2003-09-13 2005-03-24 Boots Healthcare International Limited Skincare compositions comprising salicyclic acid
CN1711845A (zh) * 2004-06-25 2005-12-28 殷生章 一种可杀灭非典肺炎冠状病毒的消毒剂
WO2009076718A1 (en) * 2007-12-17 2009-06-25 Novapharm Research (Australia) Pty Ltd Viricidal composition

Also Published As

Publication number Publication date
KR101785130B1 (ko) 2017-10-12
US8846008B2 (en) 2014-09-30
MX2012008482A (es) 2012-11-29
CA2786880A1 (en) 2011-07-28
US20130287860A1 (en) 2013-10-31
AU2011207398A1 (en) 2012-07-26
CA2786880C (en) 2018-04-24
JP6118918B2 (ja) 2017-04-19
JP5866298B2 (ja) 2016-02-17
US20120288571A1 (en) 2012-11-15
US8846009B2 (en) 2014-09-30
US9253987B2 (en) 2016-02-09
AU2011207398B2 (en) 2014-11-20
BR112012018170B1 (pt) 2021-04-06
EP2525803B1 (en) 2017-04-26
RU2570387C2 (ru) 2015-12-10
BR112012018170B8 (pt) 2021-05-25
JP2016056186A (ja) 2016-04-21
WO2011091322A3 (en) 2011-09-29
EP2525803A2 (en) 2012-11-28
BR112012018170A2 (pt) 2018-11-06
US20130287861A1 (en) 2013-10-31
KR20120117837A (ko) 2012-10-24
RU2012136147A (ru) 2014-02-27
SG182452A1 (en) 2012-08-30
JP2013518056A (ja) 2013-05-20
CN103108643A (zh) 2013-05-15
WO2011091322A2 (en) 2011-07-28

Similar Documents

Publication Publication Date Title
JP6118918B2 (ja) 抗菌剤およびその使用法
RU2739249C2 (ru) Композиция, содержащая антибиотик и диспергирующее средство или антиадгезивный агент
CN101972271B (zh) 一种二氧化氯粘膜凝胶及其制备方法
HK1180975B (en) Antimicrobial agent comprising peroxide, alcohol and chelating agent
HK1180975A (en) Antimicrobial agent comprising peroxide, alcohol and chelating agent
RU2715922C1 (ru) Способ лечения распространенного перитонита
WO2020033677A1 (en) Methods of diagnosing and treating infected implants

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1180975

Country of ref document: HK

C14 Grant of patent or utility model
GR01 Patent grant
REG Reference to a national code

Ref country code: HK

Ref legal event code: GR

Ref document number: 1180975

Country of ref document: HK

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20161026