CN103037868A - 异类叶升麻苷或其药学上可接受的盐的用途 - Google Patents

异类叶升麻苷或其药学上可接受的盐的用途 Download PDF

Info

Publication number
CN103037868A
CN103037868A CN2011800298829A CN201180029882A CN103037868A CN 103037868 A CN103037868 A CN 103037868A CN 2011800298829 A CN2011800298829 A CN 2011800298829A CN 201180029882 A CN201180029882 A CN 201180029882A CN 103037868 A CN103037868 A CN 103037868A
Authority
CN
China
Prior art keywords
isoacteoside
pharmaceutically acceptable
acceptable salt
amyloid beta
aggregation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2011800298829A
Other languages
English (en)
Inventor
林汉钦
苏慕寰
黄永名
唐静静
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sinphar Tian Li Pharmaceutical Co Ltd
Original Assignee
Sinphar Tian Li Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sinphar Tian Li Pharmaceutical Co Ltd filed Critical Sinphar Tian Li Pharmaceutical Co Ltd
Priority to CN201610646844.2A priority Critical patent/CN106176778A/zh
Publication of CN103037868A publication Critical patent/CN103037868A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/64Orobanchaceae (Broom-rape family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

异类叶升麻苷或其医药学上可接受的盐被作为一种淀粉样β肽生成、累积或聚集的抑制剂,以预防或治疗与淀粉样β肽相关性疾病或状况。

Description

PCT国内申请,说明书已公开。

Claims (1)

  1. PCT国内申请,权利要求书已公开。
CN2011800298829A 2010-06-16 2011-06-16 异类叶升麻苷或其药学上可接受的盐的用途 Pending CN103037868A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610646844.2A CN106176778A (zh) 2010-06-16 2011-06-16 异类叶升麻苷或其药学上可接受的盐的用途

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35516910P 2010-06-16 2010-06-16
US61/355,169 2010-06-16
PCT/CN2011/000998 WO2011157059A1 (zh) 2010-06-16 2011-06-16 异类叶升麻苷或其药学上可接受的盐的用途

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201610646844.2A Division CN106176778A (zh) 2010-06-16 2011-06-16 异类叶升麻苷或其药学上可接受的盐的用途

Publications (1)

Publication Number Publication Date
CN103037868A true CN103037868A (zh) 2013-04-10

Family

ID=44303534

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2011800298829A Pending CN103037868A (zh) 2010-06-16 2011-06-16 异类叶升麻苷或其药学上可接受的盐的用途
CN201610646844.2A Pending CN106176778A (zh) 2010-06-16 2011-06-16 异类叶升麻苷或其药学上可接受的盐的用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201610646844.2A Pending CN106176778A (zh) 2010-06-16 2011-06-16 异类叶升麻苷或其药学上可接受的盐的用途

Country Status (11)

Country Link
US (1) US20120009131A1 (zh)
EP (1) EP2397144B1 (zh)
JP (1) JP5968878B2 (zh)
KR (1) KR101847501B1 (zh)
CN (2) CN103037868A (zh)
AU (1) AU2011267724B2 (zh)
CA (1) CA2802441C (zh)
MY (1) MY160878A (zh)
SG (1) SG186717A1 (zh)
TW (1) TWI486162B (zh)
WO (1) WO2011157059A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2044951A1 (en) * 2007-10-02 2009-04-08 Merz Pharma GmbH & Co. KGaA The use of substances for the treatment of loss of eyesight in humans with glaucoma and other degenerative eye diseases
KR102048289B1 (ko) * 2011-12-16 2020-01-08 신파 티엔리 파머슈티컬 컴퍼니 리미티드 (항저우) 아밀로이드 β 펩타이드 관련 질환 또는 이상을 예방 또는 치료하기 위한 약학적 조성물
CN103622980A (zh) * 2013-12-12 2014-03-12 宁夏医科大学 肉苁蓉苯乙醇苷类化合物作为制备治疗骨质疏松症药物的应用及药物组合物
TWI619721B (zh) * 2014-04-10 2018-04-01 杏輝藥品工業股份有限公司 異類葉升麻苷衍生物及其製造方法與用途
TWI650131B (zh) * 2014-07-03 2019-02-11 杏輝藥品工業股份有限公司 管花肉蓯蓉萃取物之用於製備保護眼部細胞之藥品或食品用途
CN108785320A (zh) * 2018-04-13 2018-11-13 浙江大学 异毛蕊花糖苷在制备激活Nrf2-ARE信号通路的保健品/药品中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040064830A (ko) * 2003-01-10 2004-07-21 주식회사 엘컴사이언스 페닐에타노이드 유도체를 포함하는 퇴행성 뇌신경계질환의 예방 및 치료용 조성물
EP1736167A2 (en) * 2005-06-20 2006-12-27 I.R.B. Istituto Di Ricerche Biotecnologiche S.r.l. Extracts obtained from cell line cultures from plants belonging to the Oleaceae family (e.g. Syringa vulgaris), their preparation and use
WO2007125351A1 (en) * 2006-04-27 2007-11-08 Senexis Limited Pyrimidine derivatives for the treatment of amyloid-related diseases
CN101264094A (zh) * 2008-04-16 2008-09-17 西藏自治区高原生物研究所 藏波罗花苯丙素苷组合物及其制备方法和用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100500584B1 (ko) * 2002-08-12 2005-07-12 경희대학교 산학협력단 신경성장인자와 유사 작용을 갖는 육종용 추출물 및 이를함유하는 조성물
TW200416036A (en) * 2003-02-18 2004-09-01 Sinphar Pharmaceutical Co Ltd Medicinal preparation containing phenylethanoid glycosides extracted from herbaceous plant, cistanche tubulosa (schenk.) wight, process of making the same, and uses of the same
CN1268341C (zh) * 2003-03-04 2006-08-09 杏辉天力(杭州)药业有限公司 来源于管花肉苁蓉的含有苯乙醇苷的制剂及其制备方法和用途
JP2006312594A (ja) * 2005-05-06 2006-11-16 Univ Nihon 学習・記憶障害予防用組成物
JP4936507B2 (ja) * 2006-01-18 2012-05-23 学校法人近畿大学 カンカニクジュヨウの抽出物より得られる強壮剤又は強精剤、配糖体化合物及びそれらの用途
CN100446792C (zh) * 2006-03-21 2008-12-31 中国海洋大学 一种改善记忆的中药
JP5410683B2 (ja) * 2008-02-19 2014-02-05 学校法人近畿大学 カンカニクジュヨウから得られる肝保護剤及び抗TNF−α作用剤
JP2009196908A (ja) * 2008-02-20 2009-09-03 Yomeishu Seizo Co Ltd リパーゼ阻害剤及び飲食品
JP2009209063A (ja) * 2008-03-03 2009-09-17 Univ Kinki 皮膚外用剤または皮膚化粧料
JP2009263279A (ja) * 2008-04-25 2009-11-12 Oriza Yuka Kk エラスターゼ阻害剤
CN101703125B (zh) * 2009-12-04 2012-07-04 中国科学院新疆生态与地理研究所 肉苁蓉红茶及其制备方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040064830A (ko) * 2003-01-10 2004-07-21 주식회사 엘컴사이언스 페닐에타노이드 유도체를 포함하는 퇴행성 뇌신경계질환의 예방 및 치료용 조성물
EP1736167A2 (en) * 2005-06-20 2006-12-27 I.R.B. Istituto Di Ricerche Biotecnologiche S.r.l. Extracts obtained from cell line cultures from plants belonging to the Oleaceae family (e.g. Syringa vulgaris), their preparation and use
WO2007125351A1 (en) * 2006-04-27 2007-11-08 Senexis Limited Pyrimidine derivatives for the treatment of amyloid-related diseases
CN101448794A (zh) * 2006-04-27 2009-06-03 塞内希斯有限公司 用于治疗淀粉样蛋白相关性疾病的嘧啶衍生物
CN101264094A (zh) * 2008-04-16 2008-09-17 西藏自治区高原生物研究所 藏波罗花苯丙素苷组合物及其制备方法和用途

Also Published As

Publication number Publication date
WO2011157059A1 (zh) 2011-12-22
KR101847501B1 (ko) 2018-05-24
US20120009131A1 (en) 2012-01-12
CA2802441A1 (en) 2011-12-22
KR20130095246A (ko) 2013-08-27
EP2397144B1 (en) 2014-12-31
TWI486162B (zh) 2015-06-01
CA2802441C (en) 2018-08-07
CN106176778A (zh) 2016-12-07
TW201200137A (en) 2012-01-01
JP5968878B2 (ja) 2016-08-10
EP2397144A1 (en) 2011-12-21
MY160878A (en) 2017-03-31
AU2011267724A1 (en) 2013-01-24
AU2011267724B2 (en) 2016-07-28
SG186717A1 (en) 2013-02-28
JP2013528627A (ja) 2013-07-11

Similar Documents

Publication Publication Date Title
CN103037868A (zh) 异类叶升麻苷或其药学上可接受的盐的用途
MY160241A (en) 5-alkynyl-pyrimidines
CL2014000468A1 (es) Compuestos derivados del acido 2-oxo-6-(fenil/heteroaril)l-1,2-dihidropiridin-3-carboxilico; composicion farmaceutica; combinacion; y su uso para el alivio de una infeccion bacteriana.
MX352231B (es) Nuevos agentes terapeuticos.
NZ631062A (en) Bromodomain inhibitors
MX347734B (es) Anticuerpos anti-s100a4 y usos aplicaciones terapéuticas.
NZ608116A (en) Triazine-oxadiazoles
WO2013052943A3 (en) Small molecule inhibitors of mcl-1 and uses thereof
NZ601167A (en) Treatment of cardiac conditions
CR20200220A (es) FORMAS SÓLIDAS DE ÁCIDO {[5-(3-CLOROFENIL)-3-HIDROXIPIRIDIN-2-CARBONIL]AMINO}ACÉTICO, COMPOSICIONES, Y USOS DE LAS MISMAS (Divisional 2016-0222)
MY165087A (en) Neprilysin inhibitors
MX2013006805A (es) Inhibidores de la neprilisina.
IT1404931B1 (it) Composizioni oftalmiche per la somministrazione di principi attivi liposolubili .
PH12014501967B1 (en) Benzodioxanes in combination with other actives for inhibiting leukotriene production
UA109661C2 (uk) Фармацевтична композиція співкристалів трамадолу і коксибів
MX352245B (es) Formulacion farmaceutica que comprende una droga biofarmaceutica.
MX2013013801A (es) Oligodesoxinucleotidos inmunoestimuladores.
MX2013013800A (es) Oligodesoxinucleotidos inmunoestimuladores.
IN2015DN03998A (zh)
SMT201600189B (it) Soluzione acquosa comprendente 3-chinuclidinoni per il trattamento di malattie iperproliferative, autoimmuni e cardiache
WO2013007596A3 (en) Oral treatment of inflammatory bowel disease
IN2014DN01629A (zh)
EA201390948A1 (ru) Лечение боли, обусловленной смещением базального слоя эндометрия
IN2014DN10449A (zh)
PH12014501425A1 (en) Pharmaceutical preparation comprising brexpiprazole and substituted beta-cyclodextrin

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C12 Rejection of a patent application after its publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20130410