CN103007100B - Composition with functions of body slimming and waistline reduction and preparation method of composition - Google Patents
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- CN103007100B CN103007100B CN201310011619.8A CN201310011619A CN103007100B CN 103007100 B CN103007100 B CN 103007100B CN 201310011619 A CN201310011619 A CN 201310011619A CN 103007100 B CN103007100 B CN 103007100B
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Abstract
The invention discloses a composition with the functions of weight losing and waistline reduction and a preparation method of composition. The composition is prepared from the following raw materials in parts by weight: 2-4 parts of hawthorn, 2-6 parts of semen cassiae, 2-6 parts of lotus leaf, 1-3 parts of dried orange peel, 4-15 parts of poria cocos, 3-6 parts of coix seed, 2-6 parts of sealwort, 3-15 parts of astragalus mongholicus, 0.5-2 parts of ginseng, 0.1-1 part of liquorice, 0.5-1 part of white kidney bean extract and 5-10 parts of resistant starch. The composition can be prepared into granules, powder or an oral solution. The composition disclosed by the invention combines traditional Chinese medicines with functions of tonifying spleen, eliminating dampness, reducing fat and losing weight with the white kidney bean extract and the resistant starch which have definite weight-losing function mechanism by combining the mechanism study result of practitioners of Chinese medicines on fat as well as modern science research achievements; and when taking the composition disclosed by the invention, people do not need to diet intentionally, and the composition has no side effects, such as anorexia and diarrhea, achieves the tonic and weight-losing effects, has the advantages of improving the immunity of the organism and ensuring that the waistline and the weight are reduced without rebound and has the favorable efficacies of reducing waistline and losing weight.
Description
Technical field
The present invention relates to a kind of health product, be specifically related to a kind of composition and method of making the same of the thin waistline of losing weight.
Background technology
World Health Organization's report claims: obesity is 21 century to affect one of principal element of human health, and overweight people occurs that the risk of hypertension, dyslipidemia and metabolism syndrome is larger.Obesity is weighed with Body Mass Index (BMI) conventionally, BMI=body weight (kg)/height (m2), and when BMI is greater than 25 for overweight, BMI is greater than 30 for fat.But Body Mass Index (BMI) can not reflect the distribution situation of body fat, although because some patient's body fat content exceeds standard greatly, the index of its reflection metabolic risk factor is relatively normal; Otherwise, although some patients are just slightly overweight, can there are all disease performances of metabolic complication, all corresponding increases of risk of suffering from type 2 diabetes mellitus, coronary atherosclerosis and cardiovascular disease.For this reason, waistline measurement is that overweight patient just seems particularly important for BMI standard definition.Even for Normal-weight person, waistline increase is the mark that ill risk raises too.
One's waist measures prediction metabolism syndrome strong index.World Health Organization (WHO) points out for a long time, and male's waistline > 102cm, women's waistline > 88cm, occur that the risk of metabolic complication will increase.And the high-risk waistline dividing value of different ethnic groups is variant, Chinese people is male > 90cm, women > 80cm.This predictor should be independent of outside Body Mass Index.Therefore, good diet products, except losing weight, the more important thing is and will have good minimizing waistline effect.
Diet products are a lot of in the market, it is large that Western medicine fat-reducing has side effect, the shortcomings such as easy bounce-back, and most Chinese medicine formula and health food mainly with Semen Cassiae, Folium Nelumbinis extract, tea polyphenols as raw material, these products have certain thin waist weight losing function, but because effect composition is single, onset is slower, is difficult to allow obese patient establish confidence and finally abandon taking.And some illegal businessman is for reaching the effect of getting instant result, put consumer's life and safety in ignoring, in health food, add the forbidden drugs such as Western medicine, cause very big injury to consumer, bring harmful effect also to diet products market.Along with the understanding of people to health slimming theory, more and more recognize that fat-reducing is not to deduct simply body weight or moisture, but select not damage healthy, can be for the cause of disease of obesity, by overcoming, correct the too fast abnormal metabolism of overweight people's synthctic fat, just do not take stopgap measures, but fundamentally adjust the each organ of human body to recover original function, there is no the side effect such as anorexia, diarrhoea, fat-reducing effect does not rebound, deducts the unnecessary particularly fat-reducing mode of stomach fat of fat in body.
The traditional Chinese medical science thinks that fat reason is the foul coagulation of materials during the interior water of body wets, and " expectorant " in this material and lung has similar feature, in the traditional Chinese medical science, be " fertile people's excessive phlegm is wet ", since the foul coagulation of materials of fat reason during to be water wet forms, and water wet be transportation capabilities due to spleen not normal due to, so, the transportation capabilities of spleen are not normal, are exactly the fat basic reason forming.Wherein in the well-known doctor Chen Shiduo of the Qing Dynasty " the secret record in stone chamber ", say that useful invigorating the spleen for dissipating phlegm carrys out the method for the treatment of of obesity, he has proposed penetrating discussion to the origin cause of formation of obesity in book: fertile people's excessive phlegm, be the deficiency of vital energy also, void gas can not be moved, therefore expectorant life.In other words, the reason of obesity is because excessive phlegm is wet in body to the words, and it is again that the transportation capabilities wet to water go down because of deficiency-weakness of spleen-QI that phlegm-damp generates.Thereby cause turbid damp cohesion in body and become phlegm-damp.Under this theoretical direction, Chen Shiduo think treatment of obesity " must mend its gas, then band disappear its expectorant be ear ".In other words: treatment of obesity should take invigoration spleen qi (namely improving spleen to the wet transportation capabilities of water), as main, eliminating phlegm and removing dampness be auxiliary, could fundamentally remove like this obesity.
Summary of the invention
In order to solve above-mentioned deficiency and based on above-mentioned Chinese medicine defatting health idea, to the object of the present invention is to provide a kind of compositions of the thin waistline of losing weight.
Another object of the present invention is to the preparation method of the compositions that the thin waistline of above-mentioned fat-reducing is provided.
The present invention is achieved through the following technical solutions;
The lose weight compositions of thin waistline, made by the raw material of following portions by weight:
Fructus Crataegi 2-4 part, Semen Cassiae 2-6 part, Folium Nelumbinis 2-6 part, Pericarpium Citri Reticulatae 1-3 part, Poria 4-15 part, Semen Coicis 3-6 part, Rhizoma Polygonati 2-6 part, Radix Astragali 3-15 part, Radix Ginseng 0.5-2 part, Radix Glycyrrhizae 0.1-1 part, Semen Phaseoli Vulgaris extract 0.5-1 part, resistant starch 5-10 part.
Preferably, the parts by weight of each raw material are:
Fructus Crataegi 3-4 part, Semen Cassiae 3-5 part, Folium Nelumbinis 4-6 part, Pericarpium Citri Reticulatae 1-2 part, Poria 8-15 part, Semen Coicis 2-6 part, Rhizoma Polygonati 3-5 part, Radix Astragali 5-12 part, Radix Ginseng 1-2 part, Radix Glycyrrhizae 0.2-0.8 part, Semen Phaseoli Vulgaris extract 0.8-1 part, resistant starch 8-10 part.
Preferred, the parts by weight of each raw material are:
3 parts of Fructus Crataegis, 3 parts of Semen Cassiaes, 4 parts, Folium Nelumbinis, 1 part of Pericarpium Citri Reticulatae, 10 parts, Poria, 4 parts of Semen Coiciss, 4 parts of Rhizoma Polygonatis, 5 parts of the Radixs Astragali, 1 part of Radix Ginseng, 0.3 part, Radix Glycyrrhizae, 1.0 parts of Semen Phaseoli Vulgaris extract, 10 parts of resistant starch.
In the present invention, the following report of the pharmacological action of each taste Effective Component of Chinese Medicine is stated:
The Radix Astragali: benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema.Research shows, Radix Astragali saponin can suppress digesting and assimilating of fat and play antiobesity action.
Radix Ginseng: strongly invigorating primordial QI, using tonifying Qi reinforcing lungs, promoting the production of body fluid to quench thirst, Radix Ginseng and ginsenoside can reduce blood glucose, improve insulin sensitivity, lower body weight, regulate glycolipid metabolism effect.
Rhizoma Polygonati: strengthening spleen, tonifying kidney, lung moistening spermatogenesis, invigorating the spleen and replenishing QI.Modern pharmacological research shows, it is synthetic that Rhizoma Polygonati extract can suppress endogenous cholesterol, reduces exogenous cholesterol absorption, and promotes conversion and the excretion of cholesterol, and reducing atherogenic index has reducing effect to whole blood viscosity, erythrocyte sedimentation rate.
Fructus Crataegi: promoting digestion and invigorating the stomach, circulation of qi promoting scattered silt, thin waist fat-reducing.Fructus Crataegi can promote the digestion of fat food, promotes gastric secretion and increases the functions such as gastric enzyme element.
Semen Cassiae: liver heat removing and eyesight improving, loosening bowel to relieve constipation, thin waist weight reducing.Anthraquinone component in Semen Cassiae has the effect of loosening bowel to relieve constipation, hypocatharsis, can reduce serum cholesterol, reduce blood pressure and triglyceride.Semen Cassiae heat-clearing inflammation relieving, can remove because of the dysphoria with smothery sensation that diet heavy wool is greasy, environment is wet, pressure causes, recovers the normal function of body metabolism.
Folium Nelumbinis: Folium Nelumbinis chemical composition has nuciferine, citric acid, malic acid, gluconic acid, oxalic acid, succinic acid etc.; Nuciferine is to have the fat of disappearing effect.. ancient medical book is recorded: " Folium Nelumbinis takes it, makes us thin bad " China just regards as Folium Nelumbinis the good medicine of weight reducing since ancient times.
Pericarpium Citri Reticulatae: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, the greasy lasting of solution, stopping nausea and vomiting by lowering the adverse flow of QI.The bitter substance of Pericarpium Citri Reticulatae is take limonin and bitter principle as representative " limonoid ", and this limonoid taste is gentle, soluble in water, contributes to the digestion of food.Pericarpium Citri Reticulatae contains the compositions such as volatile oil, hesperidin, vitamin B, C, and its contained volatile oil has gentle stimulation to gastrointestinal tract, and pneumatosis in intestinal tube is got rid of in secretion that can facilitating digestion liquid, increases appetite.
Poria: spleen invigorating eliminating dampness by diuresis, diuretic and in.The traditional Chinese medical science thinks, the wet reciprocal causation of insufficiency of the spleen and water, so no matter be insufficiency of the spleen or water is wet to spread unchecked, application Poria can have good effect.Modern study shows, su-fuling is the effective ingredient of inducing diuresis to remove edema, is aldosterone receptor antagonist, is conducive to urine and discharges, and recovers renal function.
Semen Coicis: enhance metabolism, get rid of flatulence in body.Semen Coicis contains abundant water soluble dietary fiber, cholate in adsorbable bile, when after fibers adsorption cholate, oils and fats digest and assimilate variation, cholate cannot be recovered while use, liver need become cholate with the cholesterol metabolism of storing, and impels cholesterol to discharge from liver, and reduces blood middle cholesterol content.
Radix Glycyrrhizae: Radix Glycyrrhizae contains glycyrrhizin, Protoapigenone, terpenoid, amino acid, lignan, the compositions such as phytosterol.The Protoapigenone that Radix Glycyrrhizae includes can reduce abdominal part fat around, and the glycyrrhizin including can anti-inflammatory and promoted immunity, and clinically, Radix Glycyrrhizae is often used to the treatment of gastrointestinal ulceration, cellulitis skin infection.Separating on poison of drug and alimentary toxicosis, Radix Glycyrrhizae also has very strong curative effect.
The present invention adopts the Radix Astragali, Radix Ginseng, Rhizoma Polygonati invigorating the spleen and replenishing QI, Pericarpium Citri Reticulatae, Poria, Semen Coicis regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm, Fructus Crataegi is amusing and helps digestion, promoting blood circulation to remove blood stasis, Semen Cassiae clearing away heat-fire, Folium Nelumbinis clearing away summer-heat and eliminating dampness, Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, spleen invigorating and in, each medicine is combined, and plays altogether the merit of replenishing QI to invigorate the spleen, thin waist fat-reducing; This product is equipped with U.S. Semen Phaseoli Vulgaris extract Phase-2 and stops the decomposition of amylase to starch, reduce fat hoards simultaneously, resistant starch increases satiety, can not be digested and assimilated and provide by small intestinal glucose, but it can be by physiological bacterial fermentation in colon, produce short-chain fatty acid and gas, stimulate profitable strain growth, adjust intestinal health.
The present invention is based on Chinese medicine defatting health idea, have a high regard for science, love overweight people's health, take into full account dietary nutrition structure and the feature of obese people, in conjunction with Human Physiology factor and fat reason, fully apply subjects theory and the achievements in research such as traditional Chinese medical science Obese Mechanism, modern medicine, and the health product with the thin waistline function of fat-reducing of exploitation.
Analyze from traditional Chinese medical science angle, treatment of obesity " must mend its gas, then band disappear its expectorant be ear ".The present invention combines modern medical theory and the traditional Chinese medical science " tune, benefit clearly, " principle.When fully removing the interior superabundant fats of body, invigorating the spleen and benefiting QI, science is adjusted human gastrointestinal tract function, and balance endotrophic, without deliberately going on a diet, recovers normal nutritive equilibrium, realizes green health fat-reducing easily.
Compositions of the present invention can be made powder, granule, oral liquid.
Wherein, the present composition is made the preparation method of powder or granule, comprises the steps:
A) get Fructus Crataegi, clean, section; Folium Nelumbinis, cleans, and is cut into the silk of 0.5-1cm; Poria, Radix Ginseng coarse crushing become coarse powder; Rhizoma Polygonati, cleans, and cuts sheet; The Radix Astragali, Radix Glycyrrhizae, clean, and is cut into the section of 1-1.5cm; Semen Cassiae, Pericarpium Citri Reticulatae are selected remove impurity;
B) get Fructus Crataegi, Semen Cassiae, Folium Nelumbinis, Radix Ginseng four tastes, adding 6 ~ 10 times of amount volume ratios is that 60% ~ 90% alcohol heating reflux is carried
Get 1 ~ 2 hour, filter, obtain medicinal residues, decompression filtrate recycling ethanol, to without alcohol taste, obtains ethanol extraction concentrated solution;
C), by above-mentioned medicinal residues and Pericarpium Citri Reticulatae, Poria, Semen Coicis, Rhizoma Polygonati, the Radix Astragali, Radix Glycyrrhizae 6 tastes, decoct with water and extract twice, the first
Inferiorly add 6-15 times of water gaging, decoct 1-3 hour, add for the second time 4-10 times of water gaging, decoct 0.5-2 hour, filter merging filtrate, the extractum that concentrating under reduced pressure is 1.03-1.13 to relative density at 80 ℃;
D) ethanol extraction concentrated solution is mixed with extractum, obtains Chinese medicine extraction clear paste, get Chinese medicine extraction clear paste spray dry, control
175～185 ℃ of inlet temperature processed, 85～95 ℃ of leaving air temps, spray powder is collected in timing, obtains Chinese medicine spray powder;
E) get Chinese medicine spray powder and mix homogeneously with Semen Phaseoli Vulgaris extract, resistant starch, packing, makes powder; Or granulate, packing,
Granulation agent.
Preferably, described granulation can adopt airpillow-dry to granulate, and grain graininess is that 40 ~ 60 order granules are no less than 90%, or granulates by dry pressing, collects 20-40 order granule.
Compositions of the present invention is made the preparation method of oral liquid, comprises the steps:
A) get Fructus Crataegi, clean, section; Folium Nelumbinis, cleans, and is cut into the silk of 0.5-1cm; Poria, Radix Ginseng coarse crushing become coarse powder;
Rhizoma Polygonati, cleans, and cuts sheet; The Radix Astragali, Radix Glycyrrhizae, clean, and is cut into the section of 1-1.5cm; Semen Cassiae, Pericarpium Citri Reticulatae are selected remove impurity;
B) get Fructus Crataegi, Semen Cassiae, Folium Nelumbinis, Radix Ginseng four tastes, adding 6 ~ 10 times of amount volume ratios is 60% ~ 90% alcohol heating reflux
Extract 1 ~ 2 hour, filter, obtain medicinal residues, decompression filtrate recycling ethanol, to without alcohol taste, obtains ethanol extraction concentrated solution;
C), by above-mentioned medicinal residues and Pericarpium Citri Reticulatae, Poria, Semen Coicis, Rhizoma Polygonati, the Radix Astragali, Radix Glycyrrhizae 6 tastes, decoct with water and extract twice, the
Once add 6-15 times of water gaging, decoct 1-3 hour, add for the second time 4-10 times of water gaging, decoct 0.5-2 hour, filter merging filtrate, the extractum that concentrating under reduced pressure is 1.02-1.05 to relative density at 80 ℃;
D) ethanol extraction concentrated solution is mixed with extractum, obtain Chinese medicine extraction clear paste, add water and be adjusted to total amount 200ml, cold preservation,
Hold over night, gets supernatant, adds Semen Phaseoli Vulgaris extract, resistant starch, dissolve, and after mix homogeneously, fill, at 110 ℃, moist heat sterilization 30 minutes, makes oral liquid.
The present invention compared with prior art, has following beneficial effect:
The present invention is to fat mechanism result of study and modern scientific research achievement in conjunction with the traditional Chinese medical science, the spleen strengthening and damp drying, lowering blood-fat and reducing weight Chinese medicine and Semen Phaseoli Vulgaris extract, the resistant starch with the mechanism of action of clearly reducing weight are combined, start with from the body constitution of adjusting adiposis patient, reach weight reduction, thin waistline, do not subtract appetite, do not subtract physical conditioning fat-reducing effect.
Formula components of the present invention not only contains crude drug but also contain the effective ingredient such as extract, for raw the effective elements of the medicine in abundant this formula of extraction is as chemical compositions such as flavone, saponin, alkaloids, the present invention adopts part crude drug first to extract with alcohol heating reflux, decoct with water with other crude drug again, extract clear paste and be mixed and made into preparation with residue flavour of a drug again, extracted to greatest extent the effective ingredient in medical material; Moreover, adopt the compositions of the thin waistline of fat-reducing that this technique prepares, show through crowd's test, take this product without specially going on a diet, there is no the side effect such as anorexia, diarrhoea, tonification fat-reducing, improve immunity of organisms, thin waistline fat-reducing does not rebound, and has good thin waistline effect of weight reducing.
The specific embodiment
Further illustrate the present invention below by the specific embodiment, following examples are the concrete embodiment of the present invention, but embodiments of the present invention are not subject to the restriction of following embodiment.
The Semen Phaseoli Vulgaris extract adopting in the embodiment of the present invention is the Phase-2 of imported from America.
embodiment 1:
Crude drug proportioning:
Fructus Crataegi 3g, Semen Cassiae 3g, Folium Nelumbinis 4g, Pericarpium Citri Reticulatae 1g, Poria 10g, Semen Coicis 4g, Rhizoma Polygonati 4g, Radix Astragali 5g, Radix Ginseng 1g, Radix Glycyrrhizae 0.3g, Semen Phaseoli Vulgaris extract 1.0g, resistant starch 10g;
Preparation technology:
A) get Fructus Crataegi, clean, section; Folium Nelumbinis, cleans, and is cut into the silk of 0.5-1cm; Poria, Radix Ginseng coarse crushing become coarse powder; Rhizoma Polygonati, cleans, and cuts sheet; The Radix Astragali, Radix Glycyrrhizae, clean, and is cut into the section of 1-1.5cm; Semen Cassiae, Pericarpium Citri Reticulatae are selected remove impurity;
B) get Fructus Crataegi, Semen Cassiae, Folium Nelumbinis, Radix Ginseng four tastes, adding 8 times of amount volume ratios is that 70% alcohol heating reflux extracts 1.5 hours, filters, and obtains medicinal residues, and decompression filtrate recycling ethanol, to without alcohol taste, obtains ethanol extraction concentrated solution;
C) by above-mentioned medicinal residues and Pericarpium Citri Reticulatae, Poria, Semen Coicis, Rhizoma Polygonati, the Radix Astragali, Radix Glycyrrhizae 6 tastes, decoct with water and extract twice, add for the first time 10 times of water gagings, decoct 2 hours, add for the second time 8 times of water gagings, decoct 1 hour, filter merging filtrate, the extractum that concentrating under reduced pressure is 1.08 to relative density at 80 ℃;
D) ethanol extraction concentrated solution is mixed with extractum, obtain Chinese medicine extraction clear paste, get Chinese medicine extraction clear paste and spray dryly, control 175～185 ℃ of inlet temperature, 85～95 ℃ of leaving air temps, spray powder is collected in timing, obtains Chinese medicine spray powder;
E) get Chinese medicine spray powder and mix homogeneously with Semen Phaseoli Vulgaris extract, resistant starch, airpillow-dry is granulated, and grain graininess is that 40-60 order granules are no less than 90%;
F) after the assay was approved, packing, after product inspection is qualified, puts in storage granule.
embodiment 2:
Crude drug proportioning:
Fructus Crataegi 4g, Semen Cassiae 5g, Folium Nelumbinis 6g, Pericarpium Citri Reticulatae 2g, Poria 8g, Semen Coicis 6g, Rhizoma Polygonati 6g, Radix Astragali 12g, Radix Ginseng 2g, Radix Glycyrrhizae 0.8g, Semen Phaseoli Vulgaris extract 0.8g, resistant starch 8g;
Preparation technology:
A) get Fructus Crataegi, clean, section; Folium Nelumbinis, cleans, and is cut into the silk of 0.5-1cm; Poria, Radix Ginseng coarse crushing become coarse powder; Rhizoma Polygonati, cleans, and cuts sheet; The Radix Astragali, Radix Glycyrrhizae, clean, and is cut into the section of 1-1.5cm; Semen Cassiae, Pericarpium Citri Reticulatae are selected remove impurity;
B) get Fructus Crataegi, Semen Cassiae, Folium Nelumbinis, Radix Ginseng four tastes, adding 10 times of amount volume ratios is that 60% alcohol heating reflux extracts 2 hours, filters, and obtains medicinal residues, and decompression filtrate recycling ethanol, to without alcohol taste, obtains ethanol extraction concentrated solution;
C) by above-mentioned medicinal residues and Pericarpium Citri Reticulatae, Poria, Semen Coicis, Rhizoma Polygonati, the Radix Astragali, Radix Glycyrrhizae 6 tastes, decoct with water and extract twice, add for the first time 6 times of water gagings, decoct 1 hour, add for the second time 10 times of water gagings, decoct 2 hours, filter merging filtrate, the extractum that concentrating under reduced pressure is 1.05 to relative density at 80 ℃;
D) ethanol extraction concentrated solution is mixed with extractum, obtain Chinese medicine extraction clear paste, add water and be adjusted to total amount 200ml, cold preservation, hold over night, gets supernatant, adds Semen Phaseoli Vulgaris extract, resistant starch, dissolve, after mix homogeneously, the solution preparing is packed in 50ml or 100m bottle into gland, at 110 ℃, moist heat sterilization 30 minutes, to obtain final product;
E) after the assay was approved, packing, after product inspection is qualified, puts in storage oral liquid.
embodiment 3:
Crude drug proportioning:
Fructus Crataegi 2g, Semen Cassiae 2g, Folium Nelumbinis 2g, Pericarpium Citri Reticulatae 3g, Poria 4g, Semen Coicis 3g, Rhizoma Polygonati 3g, Radix Astragali 15g, Radix Ginseng 0.5g, Radix Glycyrrhizae 0.2g, Semen Phaseoli Vulgaris extract 0.5g, resistant starch 5g;
Preparation technology:
A) get Fructus Crataegi, clean, section; Folium Nelumbinis, cleans, and is cut into the silk of 0.5-1cm; Poria, Radix Ginseng coarse crushing become coarse powder; Rhizoma Polygonati, cleans, and cuts sheet; The Radix Astragali, Radix Glycyrrhizae, clean, and is cut into the section of 1-1.5cm; Semen Cassiae, Pericarpium Citri Reticulatae are selected remove impurity;
B) get Fructus Crataegi, Semen Cassiae, Folium Nelumbinis, Radix Ginseng four tastes, adding 6 times of amount volume ratios is that 80% alcohol heating reflux extracts 1.5 hours, filters, and obtains medicinal residues, and decompression filtrate recycling ethanol, to without alcohol taste, obtains ethanol extraction concentrated solution;
C) by above-mentioned medicinal residues and Pericarpium Citri Reticulatae, Poria, Semen Coicis, Rhizoma Polygonati, the Radix Astragali, Radix Glycyrrhizae 6 tastes, decoct with water and extract twice, add for the first time 15 times of water gagings, decoct 3 hours, add for the second time 4 times of water gagings, decoct 0.5 hour, filter, merging filtrate, the extractum that concentrating under reduced pressure is 1.13 to relative density at 80 ℃;
D) ethanol extraction concentrated solution is mixed with extractum, obtain Chinese medicine extraction clear paste, get Chinese medicine extraction clear paste and spray dryly, control 175～185 ℃ of inlet temperature, 85～95 ℃ of leaving air temps, spray powder is collected in timing, obtains Chinese medicine spray powder;
E) get Chinese medicine spray powder and mix homogeneously with Semen Phaseoli Vulgaris extract, resistant starch, make powder;
F) product inspection qualified after, warehouse-in.
Clinical trial example:
The present invention has carried out clinical experiment to 15 volunteers, volunteer carries out diet by normal custom, take on request the product 2 times of the embodiment of the present invention 1 every day, each 1 bag, in half an hour or meal, take before the meal, take continuously 30 days, body weight and the waistline of front and back taken in record, the minimizing situation of calculating body weight and waistline, result is respectively in table 1.
table 1 body weight, waistline reduce situation
From table 1 result, product of the present invention has good fat-reducing and thin waistline effect, but do not occur that the serious phenomenon reducing of body weight occurs, because monthly lose weight and should be less than 3kg by the method for weight-reducing of science, can avoid like this, because body weight subtracts to such an extent that the too fast organ that causes is physiological inadaptable, also avoiding the bounce-back of body weight.Anti-obesity mechanism of the present invention is by Chinese medicine invigorating the spleen and benefiting QI, and Semen Phaseoli Vulgaris extract suppresses amylase activity and stops amylolysis to absorb, and resistant starch is adjusted the intestines and stomach flora, and body homergy function is able to normally, reduces fat and hoards, and waistline is reduced.
Conventionally diet products generally have the function of diarrhea inducing, and product prescription of the present invention is mainly take function of spleen and stomach regulating and adjusts intestinal microbial population as main effect have certain functions of loosening bowel relieving constipation, but action temperature and, in volunteer, there is not the phenomenon of suffering from diarrhoea.
Claims (6)
1. a compositions for the thin waistline of fat-reducing, is characterized in that, is made up of the raw material of following portions by weight:
Fructus Crataegi 2-4 part, Semen Cassiae 2-6 part, Folium Nelumbinis 2-6 part, Pericarpium Citri Reticulatae 1-3 part, Poria 4-15 part, Semen Coicis 3-6 part, Rhizoma Polygonati 2-6 part, Radix Astragali 3-15 part, Radix Ginseng 0.5-2 part, Radix Glycyrrhizae 0.1-1 part, Semen Phaseoli Vulgaris extract 0.5-1 part, resistant starch 5-10 part.
2. the compositions of the thin waistline of fat-reducing according to claim 1, is characterized in that, the parts by weight of each raw material are:
Fructus Crataegi 3-4 part, Semen Cassiae 3-5 part, Folium Nelumbinis 4-6 part, Pericarpium Citri Reticulatae 1-2 part, Poria 8-15 part, Semen Coicis 2-6 part, Rhizoma Polygonati 3-5 part, Radix Astragali 5-12 part, Radix Ginseng 1-2 part, Radix Glycyrrhizae 0.2-0.8 part, Semen Phaseoli Vulgaris extract 0.8-1 part, resistant starch 8-10 part.
3. the compositions of the thin waistline of fat-reducing according to claim 2, is characterized in that, the parts by weight of each raw material are:
3 parts of Fructus Crataegis, 3 parts of Semen Cassiaes, 4 parts, Folium Nelumbinis, 1 part of Pericarpium Citri Reticulatae, 10 parts, Poria, 4 parts of Semen Coiciss, 4 parts of Rhizoma Polygonatis, 5 parts of the Radixs Astragali, 1 part of Radix Ginseng, 0.3 part, Radix Glycyrrhizae, 1.0 parts of Semen Phaseoli Vulgaris extract, 10 parts of resistant starch.
4. the preparation method of the compositions of the thin waistline of fat-reducing described in claim 1,2 or 3, is characterized in that, comprises the following steps:
A) get Fructus Crataegi, clean, section; Folium Nelumbinis, cleans, and is cut into the silk of 0.5-1cm; Poria, Radix Ginseng coarse crushing become coarse powder; Rhizoma Polygonati, cleans, and cuts sheet; The Radix Astragali, Radix Glycyrrhizae, clean, and is cut into the section of 1-1.5cm; Semen Cassiae, Pericarpium Citri Reticulatae are selected remove impurity;
B) get Fructus Crataegi, Semen Cassiae, Folium Nelumbinis, Radix Ginseng four tastes, adding 6 ~ 10 times of amount volume ratios is that 60% ~ 80% alcohol heating reflux extracts 1 ~ 2 hour, filters, and obtains medicinal residues, and decompression filtrate recycling ethanol, to without alcohol taste, obtains ethanol extraction concentrated solution;
C), by above-mentioned medicinal residues and Pericarpium Citri Reticulatae, Poria, Semen Coicis, Rhizoma Polygonati, the Radix Astragali, Radix Glycyrrhizae 6 tastes, decoct with water and extract twice, the first
Inferiorly add 6 ~ 15 times of water gagings, decoct 1 ~ 3 hour, add for the second time 4 ~ 10 times of water gagings, decoct 0.5 ~ 2 hour, filter merging filtrate, the extractum that concentrating under reduced pressure is 1.03-1.13 to relative density at 80 ℃;
D) ethanol extraction concentrated solution is mixed with extractum, obtains Chinese medicine extraction clear paste, get Chinese medicine extraction clear paste spray dry, control
175～185 ℃ of inlet temperature processed, 85～95 ℃ of leaving air temps, spray powder is collected in timing, obtains Chinese medicine spray powder;
E) get Chinese medicine spray powder and mix homogeneously with Semen Phaseoli Vulgaris extract, resistant starch, packing, makes powder; Or granulate, packing, granulation agent.
5. the preparation method of the compositions of the thin waistline of fat-reducing according to claim 4, is characterized in that, described granulation is to adopt airpillow-dry to granulate, and grain graininess is 40-60 orders, and granule is no less than 90%, or granulates by dry pressing, collects 20-40 order granule.
6. the preparation method of the compositions of the thin waistline of fat-reducing described in claim 1,2 or 3, is characterized in that, comprises the following steps:
A) get Fructus Crataegi, clean, section; Folium Nelumbinis, cleans, and is cut into the silk of 0.5-1cm; Poria, Radix Ginseng coarse crushing become coarse powder; Rhizoma Polygonati, cleans, and cuts sheet; The Radix Astragali, Radix Glycyrrhizae, clean, and is cut into the section of 1-1.5cm; Semen Cassiae, Pericarpium Citri Reticulatae are selected remove impurity;
Get Fructus Crataegi, Semen Cassiae, Folium Nelumbinis, Radix Ginseng four tastes, adding 6 ~ 10 times of amount volume ratios is that 60% ~ 90% alcohol heating reflux extracts 1 ~ 2 hour, filters, and obtains medicinal residues, and decompression filtrate recycling ethanol, to without alcohol taste, obtains ethanol extraction concentrated solution;
C) by above-mentioned medicinal residues and Pericarpium Citri Reticulatae, Poria, Semen Coicis, Rhizoma Polygonati, the Radix Astragali, Radix Glycyrrhizae 6 tastes, decoct with water and extract twice, add for the first time 6 ~ 15 times of water gagings, decoct 1 ~ 3 hour, add for the second time 4 ~ 10 times of water gagings, decoct 0.5 ~ 2 hour, filter, merging filtrate, the extractum that concentrating under reduced pressure is 1.02-1.05 to relative density at 80 ℃;
D) ethanol extraction concentrated solution is mixed with extractum, obtain Chinese medicine extraction clear paste, add water and be adjusted to total amount 200ml, cold preservation, hold over night, gets supernatant, adds Semen Phaseoli Vulgaris extract, resistant starch, dissolves, after mix homogeneously, fill, at 110 ℃, moist heat sterilization 30 minutes, makes oral liquid.
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Effective date of registration: 20231117 Address after: No. 21 and 22, Qifeng Industrial Zone, Ganjiao Community, Lishui Town, Nanhai District, Foshan City, Guangdong Province, 528200 Patentee after: Guangdong Qifeng Health Industry Co.,Ltd. Address before: 528244 Qifeng Industrial Development Zone, Lishui Town, Nanhai District, Foshan City, Guangdong Province Patentee before: GUANGDONG YIFANG PHARMACEUTICAL Co.,Ltd. |