CN103007022A - Compound propolis composition for treating mastitis of dairy cows and preparation method of composition - Google Patents
Compound propolis composition for treating mastitis of dairy cows and preparation method of composition Download PDFInfo
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- CN103007022A CN103007022A CN2012105161706A CN201210516170A CN103007022A CN 103007022 A CN103007022 A CN 103007022A CN 2012105161706 A CN2012105161706 A CN 2012105161706A CN 201210516170 A CN201210516170 A CN 201210516170A CN 103007022 A CN103007022 A CN 103007022A
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Abstract
The invention relates to a compound propolis composition for treating mastitis of dairy cows. The compound propolis composition is prepared by mixing the following components in part by weight: 15-35 parts of propolis, 15-35 parts of trichosanthes kirilowii maxim, 15-30 parts of herba violae, 15-35 parts of radix paeoniae rubra, 15-35 parts of frankincense, 15-35 parts of myrrh, 15-30 parts of bulbus fritillariae thunbergii, 15-35 parts of houttuynia cordata, 15-45 parts of kelp and 15-35 parts of golden cypress. The compound propolis composition has unique advantages compared with western medicines by adopting the multiple pure traditional Chinese medicine components, is reasonable in composition, simple to prepare, free from pollution and low in cost, has no medicine residues and toxic and side effects, and is effective in treatment.
Description
Technical field
The present invention relates to compound bee-glue composition for the treatment of mammitis of cow and preparation method thereof, belong to the animal field of medicaments, particularly relate to a kind of compound bee-glue composition for the treatment of mammitis of cow and preparation method thereof.
Background technology
Mammitis of cow is that milch cow is before just before giving birth or the common a kind of multiple diseases of pregnancy duration, the multiple lactation period of being born in breast usefulness milch cow, primary disease is the commonly encountered diseases frequently-occurring disease in the milk cattle cultivating process, sometimes even the life security that jeopardizes female animal and newborn animal thereof, be to cause one of the most serious disease of milch cow economic loss.
Chinese veterinarian thinks that this disease system stops up heat because of female animal three warmers in antenatal puerperal, pyretic toxicity multiple abscess breast and swell swollenly, or the inaccessible milk of mammary gland is accumulated, or polygalactia and the young stock amount of sucking is few, or puerperal, young stock was dead, and milk can not dissipate, accumulate within the breast, pent-up forms primary disease.
Present medicine effect is outstanding not, can produce drug resistance again with the existing drug residue of western medicine, and environment and human health are constituted a serious threat.Therefore researching and developing a kind of specific medicament for the treatment of mammitis of cow is one of this field scientific research technical staff new problem anxious to be resolved.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, successful, drug residue free, have no side effect, effectively treat compound bee-glue composition of mammitis of cow and preparation method thereof.
Implementation of the present invention is as follows for achieving the above object: a kind of compound bee-glue composition for the treatment of mammitis of cow, by following component by weight mixed preparing form: 15～35 parts of propolis, 15～35 parts of Fructus Trichosanthis, 15～30 parts of Herba Violaes, 15～35 parts of Radix Paeoniae Rubra, 15～35 parts of Olibanums, 15～35 parts of Myrrhas, 15～30 parts of Bulbus Fritillariae Thunbergiis, 15～35 parts of Herba Houttuyniae, 15～45 parts of Thallus Laminariae (Thallus Eckloniae)s, 15～35 parts of Cortex Phellodendris.
Described various component optimum ratio amount is: 25 parts of propolis, 25 parts of Fructus Trichosanthis, 20 parts of Herba Violaes, 25 parts of Radix Paeoniae Rubra, 25 parts of Olibanums, 25 parts of Myrrhas, 20 parts of Bulbus Fritillariae Thunbergiis, 25 parts of Herba Houttuyniae, 30 parts of Thallus Laminariae (Thallus Eckloniae)s, 25 parts of Cortex Phellodendris.
A kind of preparation method for the treatment of the compound bee-glue composition of mammitis of cow, carry out as follows:
(1) the various compositions in the prescription is carried out respectively cross 700 mesh sieves after the micronizing;
(2) proportioning takes by weighing 15～35 parts of propolis, 15～35 parts of Fructus Trichosanthis, 15～30 parts of Herba Violaes, 15～35 parts of Radix Paeoniae Rubra, 15～35 parts of Olibanums by weight, mixes 5～10 minutes;
(3) proportioning takes by weighing 15～35 parts of Myrrhas, 15～30 parts of Bulbus Fritillariae Thunbergiis, 15～35 parts of Herba Houttuyniae, 15～45 parts of Thallus Laminariae (Thallus Eckloniae)s, 15～35 parts of Cortex Phellodendris by weight, mixes 5～10 minutes;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10～15 minutes, mix homogeneously.
The medicinal property of each component is as follows:
Propolis: bitter, hot, cold, return spleen, lung, stomach warp, have anti-bacteria and anti-virus, antalgesic-antipruritic, promotion tissue regeneration, improve immunity, antiallergic oxidation, stop blooding, moisturize, the function of relieving cough and asthma, protection gastrointestinal mucosa.
Fructus Trichosanthis:.Sweet, bitter, cold, return lung, stomach, large intestine channel, have the function of removing heat-phlegm, promoting the circulation of QI eliminating stagnation, moistening dryness for relaxing bowels; Cure mainly cough due to lung-heat, chest and diaphragm pain, acute mastitis, feces drying etc.
Herba Violae: bitter, hot, cold, GUIXIN, Liver Channel have the function of heat-clearing and toxic substances removing, removing heat from blood detumescence; Cure mainly the yellow furunculosis of skin ulcer, conjunctival congestion and swelling pain etc.
Radix Paeoniae Rubra: bitter, be slightly cold, return Liver Channel, have the function of clearing away heat and cooling blood, eliminating stasis to stop pain; Cure mainly maculae caused by violent heat pathogen, the hot hematochezia of intestinal, conjunctival congestion and swelling pain, too fat to move skin infection, traumatic injury etc.
Olibanum: hot, bitter, warm, GUIXIN, liver, spleen channel have the function of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, expelling pus and promoting granulation; Cure mainly traumatic injury, too fat to move skin infection, qi depression to blood stasis etc.
Myrrha: hot, bitter, flat, GUIXIN, liver, spleen channel have the function of promoting flow of QI and blood, subduing swelling and relieving pain, expelling pus and promoting granulation; Cure mainly too fat to move skin infection, traumatic injury etc.
Bulbus Fritillariae Thunbergii: bitter, cold, GUIXIN, lung meridian have the function of heat clearing away eliminating stagnation, preventing phlegm from forming and stopping coughing; Cure mainly cough due to lung-heat, lung abscess, acute mastitis, sore swollen toxin etc.
Herba Houttuyniae: hot, be slightly cold, return lung meridian, have the functions such as heat-clearing and toxic substances removing, detumescence and apocenosis, inducing diuresis for treating stranguria syndrome, cure mainly dysentery, intestinal Huang, lung abscess, acute mastitis, stranguria with turbid discharge etc.
Thallus Laminariae (Thallus Eckloniae): salty, cold, return stomach, liver, kidney channel, have the function of hard masses softening and resolving, expectorant, diuretic; Curing mainly edema gathers etc.
Cortex Phellodendri: bitter, cold, return kidney, urinary bladder channel, have the function of heat clearing and damp drying, eliminating fire and detoxication, reducing the asthenic fever; Cure mainly damp-heat dysentery, jaundice, pyretic stranguria, sore swollen toxin, eczema, hyperactivity of fire caused by deficiency of YIN etc.
Above all flavor Chinese medicine for the various paathogenic factors that cause mammitis of cow, is brought into play the effect for the treatment of both the principal and secondary aspects of a disease according to the tcm theory compatible combination.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Pure Chinese medicine composition is pollution-free, no drug residue, and cost is low, draws materials wide the curative effect highly significant.Select the multi-flavor pure Chinese medicinal preparation, have the not available unique advantage of Western medicine.Theoretical according to the tradition Chinese veterinarian of motherland, optimize this ten herbal medicine, and make them form compound preparation according to best proportioning, clinical practice proves that the treatment mammitis of cow is had specially good effect.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of compound bee-glue composition for the treatment of mammitis of cow and preparation method thereof carries out: (every part by 10g) as follows
(1) the various compositions in the prescription is carried out respectively cross 700 mesh sieves after the micronizing;
(2) proportioning takes by weighing 150 parts of propolis, 150 parts of Fructus Trichosanthis, 150 parts of Herba Violaes, 150 parts of Radix Paeoniae Rubra, 150 parts of Olibanums by weight, mixes 5～10 minutes;
(3) proportioning takes by weighing 150 parts of Myrrhas, 150 parts of Bulbus Fritillariae Thunbergiis, 150 parts of Herba Houttuyniae, 150 parts of Thallus Laminariae (Thallus Eckloniae)s, 150 parts of Cortex Phellodendris by weight, mixes 5～10 minutes;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10～15 minutes, mix homogeneously.
Embodiment 2
A kind of compound bee-glue composition for the treatment of mammitis of cow and preparation method thereof carries out: (every part by 10g) as follows
(1) the various compositions in the prescription is carried out respectively cross 700 mesh sieves after the micronizing;
(2) proportioning takes by weighing 250 parts of propolis, 250 parts of Fructus Trichosanthis, 200 parts of Herba Violaes, 250 parts of Radix Paeoniae Rubra, 250 parts of Olibanums by weight, mixes 5～10 minutes;
(3) proportioning takes by weighing 250 parts of Myrrhas, 200 parts of Bulbus Fritillariae Thunbergiis, 250 parts of Herba Houttuyniae, 300 parts of Thallus Laminariae (Thallus Eckloniae)s, 250 parts of Cortex Phellodendris by weight, mixes 5～10 minutes;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10～15 minutes, mix homogeneously.
Embodiment 3
A kind of compound bee-glue composition for the treatment of mammitis of cow and preparation method thereof carries out: (every part by 10g) as follows
(1) the various compositions in the prescription is carried out respectively cross 700 mesh sieves after the micronizing;
(2) proportioning takes by weighing 350 parts of propolis, 350 parts of Fructus Trichosanthis, 300 parts of Herba Violaes, 350 parts of Radix Paeoniae Rubra, 350 parts of Olibanums by weight, mixes 5～10 minutes;
(3) proportioning takes by weighing 350 parts of Myrrhas, 300 parts of Bulbus Fritillariae Thunbergiis, 350 parts of Herba Houttuyniae, 450 parts of Thallus Laminariae (Thallus Eckloniae)s, 350 parts of Cortex Phellodendris by weight, mixes 5～10 minutes;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10～15 minutes, mix homogeneously.
Clinical trial:
The clinical experiment animal is selected the 380-450 age in days, and Laboratory Diagnosed is the milch cow of mammitis of cow, its isolation is raised separately, and the complete feed of feeding, and be divided at random 3 groups, and 30 every group, 3 groups of feeding environments are identical, and test period is 7 days; The blank group is left intact, and the medicine matched group uses treatment with " YIMUSHENGHUA SAN " by specification; Chinese medicine composition group of the present invention can be got soup with product of the present invention (embodiment of the invention 1 prepared compositions) decocting, waits temperature and gavages ill milch cow, and a day dose is: by every 120g, every day 1-2 time, be used in conjunction 2-3 days.Chinese medicinal liquor gavages after decocting, the oral rear purpose that reaches the treatment disease by gastrointestinal absorption.Computational methods: mortality rate=dead animal number/experimental animal number * 100%, cure rate=healing number of animals/experimental animal number * 100%.Result's (testing the 7th day) when following table is the experiment end.
Table is used the situation of traditional Chinese medicine composition for treating mammitis of cow of the present invention clinically:
| Numbering | Group | Mortality rate % | Cure rate % | Symptom rate % is arranged during end |
| I | The blank group | 3.3 | 56.7 | 40.0 |
| II | The YIMUSHENGHUA SAN group | 0 | 86.7 | 13.3 |
| III | Present composition group | 0 | 96.7 | 3.3 |
This clinical effectiveness statistical analysis, present composition treatment group is being compared difference extremely significantly (P＜0.01) with the YIMUSHENGHUA SAN group aspect the cure rate.
Safety testing:
Choose 10 of 220 age in days healthy cows, 5 times according to the embodiment of the invention 1 made compositions recommended dose gavage 5 days, and during the medication, healthy cow is without any bad or Deviant Behavior performance, the drinking-water of searching for food is normal, and to compare difference not remarkable with blank group (being not administration of health group).
Above-mentioned detailed description of compound bee-glue composition of this treatment mammitis of cow and preparation method thereof being carried out with reference to embodiment; illustrative rather than determinate; can list several embodiment according to institute's limited range; therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.
Claims (3)
1. compound bee-glue composition for the treatment of mammitis of cow, it is characterized in that by following component by weight mixed preparing form: 15～35 parts of propolis, 15～35 parts of Fructus Trichosanthis, 15～30 parts of Herba Violaes, 15～35 parts of Radix Paeoniae Rubra, 15～35 parts of Olibanums, 15～35 parts of Myrrhas, 15～30 parts of Bulbus Fritillariae Thunbergiis, 15～35 parts of Herba Houttuyniae, 15～45 parts of Thallus Laminariae (Thallus Eckloniae)s, 15～35 parts of Cortex Phellodendris.
2. the compound bee-glue composition for the treatment of mammitis of cow according to claim 1, it is characterized in that by following component by weight mixed preparing form: 25 parts of propolis, 25 parts of Fructus Trichosanthis, 20 parts of Herba Violaes, 25 parts of Radix Paeoniae Rubra, 25 parts of Olibanums, 25 parts of Myrrhas, 20 parts of Bulbus Fritillariae Thunbergiis, 25 parts of Herba Houttuyniae, 30 parts of Thallus Laminariae (Thallus Eckloniae)s, 25 parts of Cortex Phellodendris.
3. the preparation method of the compound bee-glue composition of a treatment mammitis of cow according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription is carried out respectively cross 700 mesh sieves after the micronizing;
(2) proportioning takes by weighing 15～35 parts of propolis, 15～35 parts of Fructus Trichosanthis, 15～30 parts of Herba Violaes, 15～35 parts of Radix Paeoniae Rubra, 15～35 parts of Olibanums by weight, mixes 5～10 minutes;
(3) proportioning takes by weighing 15～35 parts of Myrrhas, 15～30 parts of Bulbus Fritillariae Thunbergiis, 15～35 parts of Herba Houttuyniae, 15～45 parts of Thallus Laminariae (Thallus Eckloniae)s, 15～35 parts of Cortex Phellodendris by weight, mixes 5～10 minutes;
(4) merge the compositions that above-mentioned steps (2) and (3) makes, remix 10～15 minutes, mix homogeneously.
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| CN201210516170.6A CN103007022B (en) | 2012-11-22 | 2012-11-22 | Compound propolis composition for treating mastitis of dairy cows and preparation method of composition |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104667166A (en) * | 2013-12-03 | 2015-06-03 | 天津市中敖饲料有限公司 | Traditional Chinese medicine composition for treating clinical mastitis of dairy cow and preparation method of traditional Chinese medicine composition |
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| CN101912586A (en) * | 2010-08-27 | 2010-12-15 | 葛德钜 | Medicament for treating mammary gland hyperplasia and preparation method thereof |
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| CN102488814A (en) * | 2011-12-22 | 2012-06-13 | 中国农业科学院北京畜牧兽医研究所 | Chinese medicinal composition for treating bovine mastitis |
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| CN101224291A (en) * | 2008-01-07 | 2008-07-23 | 李显成 | Plaster for treating breast nodules and preparing method thereof |
| CN101912586A (en) * | 2010-08-27 | 2010-12-15 | 葛德钜 | Medicament for treating mammary gland hyperplasia and preparation method thereof |
| CN102119977A (en) * | 2011-03-03 | 2011-07-13 | 天津瑞贝特科技发展有限公司 | Chinese medicinal infusion solution for treating bovine mastitis and preparation method thereof |
| CN102488814A (en) * | 2011-12-22 | 2012-06-13 | 中国农业科学院北京畜牧兽医研究所 | Chinese medicinal composition for treating bovine mastitis |
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| CN104667166A (en) * | 2013-12-03 | 2015-06-03 | 天津市中敖饲料有限公司 | Traditional Chinese medicine composition for treating clinical mastitis of dairy cow and preparation method of traditional Chinese medicine composition |
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