CN103006531A - Toothpaste capable of preventing oral ulcers, and preparation method and application thereof - Google Patents
Toothpaste capable of preventing oral ulcers, and preparation method and application thereof Download PDFInfo
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- CN103006531A CN103006531A CN 201210569474 CN201210569474A CN103006531A CN 103006531 A CN103006531 A CN 103006531A CN 201210569474 CN201210569474 CN 201210569474 CN 201210569474 A CN201210569474 A CN 201210569474A CN 103006531 A CN103006531 A CN 103006531A
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- 239000000606 toothpaste Substances 0.000 title claims abstract description 51
- 229940034610 toothpaste Drugs 0.000 title claims abstract description 50
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 208000007117 Oral Ulcer Diseases 0.000 title abstract description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 51
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 51
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims abstract description 17
- 239000001814 pectin Substances 0.000 claims abstract description 17
- 235000010987 pectin Nutrition 0.000 claims abstract description 17
- 229920001277 pectin Polymers 0.000 claims abstract description 17
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims abstract description 17
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 13
- QQILFGKZUJYXGS-UHFFFAOYSA-N Indigo dye Chemical compound C1=CC=C2C(=O)C(C3=C(C4=CC=CC=C4N3)O)=NC2=C1 QQILFGKZUJYXGS-UHFFFAOYSA-N 0.000 claims abstract description 9
- 208000002399 aphthous stomatitis Diseases 0.000 claims abstract description 9
- 206010006326 Breath odour Diseases 0.000 claims abstract description 6
- 208000004371 toothache Diseases 0.000 claims abstract description 6
- 241000237636 Pheretima Species 0.000 claims description 16
- 208000020670 canker sore Diseases 0.000 claims description 14
- 239000000843 powder Substances 0.000 claims description 14
- 239000000203 mixture Substances 0.000 claims description 11
- 239000006072 paste Substances 0.000 claims description 9
- 235000000177 Indigofera tinctoria Nutrition 0.000 claims description 8
- 229940097275 indigo Drugs 0.000 claims description 8
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 claims description 8
- 208000032139 Halitosis Diseases 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 208000025865 Ulcer Diseases 0.000 claims description 3
- 238000012856 packing Methods 0.000 claims description 3
- 231100000397 ulcer Toxicity 0.000 claims description 3
- 238000005303 weighing Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 8
- 201000010099 disease Diseases 0.000 abstract description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 7
- 208000002193 Pain Diseases 0.000 abstract description 2
- 230000002411 adverse Effects 0.000 abstract description 2
- 230000035876 healing Effects 0.000 abstract description 2
- 238000000034 method Methods 0.000 abstract description 2
- 230000004089 microcirculation Effects 0.000 abstract description 2
- 231100000252 nontoxic Toxicity 0.000 abstract description 2
- 230000003000 nontoxic effect Effects 0.000 abstract description 2
- 230000036407 pain Effects 0.000 abstract description 2
- 230000008569 process Effects 0.000 abstract description 2
- 208000024891 symptom Diseases 0.000 abstract description 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 241001313857 Bletilla striata Species 0.000 abstract 1
- 235000006481 Colocasia esculenta Nutrition 0.000 abstract 1
- 244000205754 Colocasia esculenta Species 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 241000243684 Lumbricus Species 0.000 abstract 1
- 240000002853 Nelumbo nucifera Species 0.000 abstract 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 abstract 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- 230000000249 desinfective effect Effects 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 235000012907 honey Nutrition 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
- 230000008961 swelling Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 239000000551 dentifrice Substances 0.000 description 7
- 238000004090 dissolution Methods 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 238000011161 development Methods 0.000 description 5
- 230000003239 periodontal effect Effects 0.000 description 5
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 4
- 239000011737 fluorine Substances 0.000 description 4
- 229910052731 fluorine Inorganic materials 0.000 description 4
- 210000004195 gingiva Anatomy 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 description 3
- 210000000214 mouth Anatomy 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 206010018276 Gingival bleeding Diseases 0.000 description 2
- 208000024283 Gingival haemorrhages Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 210000002200 mouth mucosa Anatomy 0.000 description 2
- 235000002639 sodium chloride Nutrition 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 239000011573 trace mineral Substances 0.000 description 2
- 235000013619 trace mineral Nutrition 0.000 description 2
- 239000009306 yunnan baiyao Substances 0.000 description 2
- 206010016818 Fluorosis Diseases 0.000 description 1
- 206010018275 Gingival atrophy Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000025157 Oral disease Diseases 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 241000238371 Sepiidae Species 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000001741 anti-phlogistic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229940036811 bone meal Drugs 0.000 description 1
- 239000002374 bone meal Substances 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- -1 can cleaning teeth Substances 0.000 description 1
- 208000002925 dental caries Diseases 0.000 description 1
- 208000004042 dental fluorosis Diseases 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 231100000734 genotoxic potential Toxicity 0.000 description 1
- 201000005562 gingival recession Diseases 0.000 description 1
- 208000007565 gingivitis Diseases 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 208000030194 mouth disease Diseases 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 230000001473 noxious effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229940095688 toothpaste product Drugs 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
- 235000001892 vitamin D2 Nutrition 0.000 description 1
- 239000011653 vitamin D2 Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
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- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to toothpaste capable of preventing oral ulcers, and a preparation method and an application thereof, and belongs to the technical field of medicinal toothpaste. The toothpaste comprises 8-13 parts of as arum, 5-9 parts of lotus seeds, 13-16 parts of bletilla striata, 7-11 parts of lumbricus, 5-9 parts of rushes, 7-11 parts of indigo naturalis, 3-6 parts of honey, 5-9 parts of pectin, 2-5 parts of borneol, 8-12 parts of sodium lauryl sulfate, 10-16 parts of propylene glycol and 6-10 parts of glycerol. The toothpaste contains a plurality of active ingredients, has the effects of disinfecting and disminishing inflammation, alleviating pains and swelling, clearing heat and removing toxicity, healing the oral ulcers, improving microcirculation of infected parts, battling bad breath and the like, and has good effects for diseases such as aphtha, toothache due to wind-fire evil, the oral ulcers, etc. The product is natural and non-toxic, has no adverse side effect, is simple in process, is safe and effective, and is low in cost. The toothpaste can treat both symptoms and root causes of the oral ulcers which are not easy to recur after recovery.
Description
Technical field
The invention belongs to medicinal toothpaste technical field, be specifically related to toothpaste of a kind of preventing canker sore and its production and use.
Background technology
Toothpaste is cleaning supplies commonly used in the daily life, and very long history is arranged.Along with the development of science and technology, technological equipment update and perfect, various types of toothpaste are come out one after another, quality and the class of product improve constantly, now toothpaste variety develops into great variety of goods, diverse in function by single clean type toothpaste.Before the use of product of cleaning the teeth can be traced back to 2000-2500, the record of using dentifrice is arranged in Greek, Roman, Hebrew people and Buddhist's the early stage works, the early stage product that clean the teeth mainly are chalky soil, animal bone powder, Pumex even Aerugo, until 19th-century is also using Os Bovis seu Bubali powder and cuttlefish bone meal to make dentifrice.Brush teeth and saline is gargled so far and yet to be existed with Sal.People had found ancient Egypt's dried tuber paper in the basement of Austrian National Library in 2003, and the above writes has expired eccentric pictograph.The above has described a kind of powder that can the brilliant white tooth, and these powder run into saliva, will become paste, can cleaning teeth, and its composition is: 1% ounce rock salt and Rhizoma Iridis Tectori dry flower, 2% ounce Herba Menthae and 20 Fructus Piperiss.Here it is toothpaste that the ancient Egyptian uses.China is in period the Tang Dynasty, and the Chinese medicine levigations such as Rhizoma Gastrodiae commonly used, Rhizoma Ligustici, Lignum Aquilariae Resinatum, Mirabilitum crystallina are wiped tooth, and this can cleaning teeth and removes mouth odor.To 18th century, Britain at first begins suitability for industrialized production dentifrice, and at this moment dentifrice just becomes a kind of commodity.The Frenchman had invented metal hose in 1840, and for some articles for daily use provide suitable packing, this has caused the reform of some commodity forms.Viennese in 1893 fills in lattice and has invented toothpaste and toothpaste is packed in the flexible pipe, and from then on toothpaste begins a large amount of development and replaces gradually dentifrice.Toothpaste is to improve on the basis of dentifrice to form, early stage dentifrice mainly with calcium carbonate as abrasivus, take soap as surfactant.Last century, the forties rose, because the developing rapidly of science and technology, toothpaste industry also obtains very large improvement, on the one hand was the development and application of new abrasivus, wetting agent, thickening agent and surfactant, and the tooth paste product quality is constantly upgraded; On the other hand, toothpaste also becomes the dental care product of preventing and treating odontopathy from the common function development that cleans the teeth for adding medicine, and the most outstanding is to add fluorine toothpaste, and the dental caries sickness rate is greatly reduced.Development along with science and technology, technological equipment update and perfect, various types of toothpaste are come out one after another, quality and the class of product improve constantly, toothpaste variety develops into great variety of goods, diverse in function by single clean type toothpaste now, the Mobyneb toothpaste of up to a hundred brands has satisfied the needs of different levels level of consumption.Toothpaste is a feast for the eyes on the market at present, and wherein quite a few is toothpaste with fluoride, but, the expert points out, child below 6 years old uses toothpaste with fluoride to have greater risk, because fluorine is a kind of noxious substance, excessive fluorine not only can cause tooth thin, more can reduce the hardness of bone.Fluorine is by the trace element of World Health Organization's identification with genotoxic potential, and plumbous hydrargyrum trace element comes one.In state-owned more than 20 provinces and cities belong to fluorosis, use toothpastes with fluoride to make the matter worse undoubtedly in these areas.
Protection gingiva, periodontal tissue seem more urgent for the adult now.The part Chinese herbal toothpaste can really play the effect of general protection tooth, gingiva, periodontal tissue.For example, YUNNAN BAIYAO toothpaste, it can prevent rapidly the oral problem such as gingival hemorrhage, prevention of gingivitis, periodontitis, gingival atrophy.Certainly, this depends on the active component of YUNNAN BAIYAO in the toothpaste, can effectively improve the blood circulation of gingiva, periodontal tissue and oral mucosa, improve the supply of periodontal tissue and oral cavity mucous membrane tissue nutrient, strengthen the resistance against diseases of gingiva, periodontal, tooth and oral mucosa.But can not too rely on for hemostatic medicated toothpaste, also can not abuse.Because the dental gingival hemorrhage is the sign of some disease, if use too early medicated toothpaste easily to cover disease symptoms, miss diagnosis and treatment opportunitys.
Summary of the invention
For the above-mentioned problems in the prior art, the object of the invention is to design the technical scheme of toothpaste that a kind of preventing canker sore is provided and its production and use, its preparation method is simple, safe and effective, low production cost, treating both the principal and secondary aspects of a disease, evident in efficacy, be difficult for recurrence after more, use easy.
The toothpaste of described a kind of preventing canker sore is characterized in that containing the following material of percentage by weight: 6～15 parts of Herba Asaris, 4～10 parts of Plumula Nelumbinis, 11～17 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 6～13 parts of Pheretimas, 4～10 parts of Medulla Juncies, 6～13 parts of Indigo Naturaliss, 2～7 parts of Mel, 4～11 parts of pectin, 1～7 part of Borneolum Syntheticum, 5～13 parts of sodium laurylsulfates, 8～17 parts of propylene glycol, 4～11 parts of glycerol.
The toothpaste of described a kind of preventing canker sore is characterized in that containing: 8～13 parts of Herba Asaris, 5～9 parts of Plumula Nelumbinis, 13～16 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 7～11 parts of Pheretimas, 5～9 parts of Medulla Juncies, 7～11 parts of Indigo Naturaliss, 3～6 parts of Mel, 5～9 parts of pectin, 2～5 parts of Borneolum Syntheticums, 8～12 parts of sodium laurylsulfates, 10～16 parts of propylene glycol, 6～10 parts of glycerol.
The toothpaste of described a kind of preventing canker sore is characterized in that containing: 10～12 parts of Herba Asaris, 6～7 parts of Plumula Nelumbinis, 14～15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 8～10 parts of Pheretimas, 6～8 parts of Medulla Juncies, 8～9 parts of Indigo Naturaliss, 4～5 parts of Mel, 6～7 parts of pectin, 3～4 parts of Borneolum Syntheticums, 9～10 parts of sodium laurylsulfates, 12～14 parts of propylene glycol, 8～9 parts of glycerol.
The preparation method of the toothpaste of described a kind of preventing canker sore is characterized in that may further comprise the steps:
1) takes by weighing the following material of weight ratio: 6～15 parts of Herba Asaris, 4～10 parts of Plumula Nelumbinis, 11～17 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 6～13 parts of Pheretimas, 4～10 parts of Medulla Juncies, 6～13 parts of Indigo Naturaliss, 2～7 parts of Mel, 4～11 parts of pectin, 1～7 part of Borneolum Syntheticum, 5～13 parts of sodium laurylsulfates, 8～17 parts of propylene glycol, 4～11 parts of glycerol, for subsequent use;
2) with Herba Asari, Plumula Nelumbinis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Pheretima, Medulla Junci, Indigo Naturalis, mix homogeneously all is ground into 600-800 order fine powder, and is for subsequent use;
3) with step 2) Mel, pectin, Borneolum Syntheticum, sodium laurylsulfate, propylene glycol, the glycerol of gained fine powder and described ratio is mixed into paste, packing toothpaste.
The application of the toothpaste of described a kind of preventing canker sore in the anti-treating dental ulcer of preparation, halitosis, aphtha, preparation for curing toothache.
Toothpaste of above-mentioned a kind of preventing canker sore and its production and use, this toothpaste contains the various active composition, have bactericidal antiphlogistic, alleviating pain and detumescence, heat-clearing and toxic substances removing, healing oral ulcer, improve the affected part microcirculation, eliminate the effect of the aspects such as halitosis, the diseases such as boil on the nape opposite the mouth, acute toothache, oral ulcer have good effect, the product Nantural non-toxic, without any adverse side effect, preparation technology is easy, safe and effective, with low cost.The characteristics such as this toothpaste is difficult for recurring, accumulating is easy to ulcer treating both the principal and secondary aspects of a disease fond of food that is not salty and more.
The percentage composition that relates in the present specification unless otherwise indicated, other be weight percentage.
The specific embodiment
Below the invention will be further described by specific embodiment, and further specify beneficial effect of the present invention in conjunction with the test of pesticide effectiveness.
Embodiment 1
In clean 2L container, add 80g Herba Asari, 50g Plumula Nelumbinis, the 130g Pseudobulbus Bletillae (Rhizoma Bletillae), 70g Pheretima, 50g Medulla Junci and 70g Indigo Naturalis, mix homogeneously, be ground into 800 order fine powders, add at last 30g Mel, 50g pectin, 20g Borneolum Syntheticum, 80g sodium laurylsulfate, 100g propylene glycol and 60g glycerol, mixed dissolution evenly becomes paste, final products.
Embodiment 2
In clean 2L container, add 110g Herba Asari, 70g Plumula Nelumbinis, the 145g Pseudobulbus Bletillae (Rhizoma Bletillae), 80g Pheretima, 60g Medulla Junci and 80g Indigo Naturalis, mix homogeneously, be ground into 600 order fine powders, add at last 45g Mel, 60g pectin, 30g Borneolum Syntheticum, 90g sodium laurylsulfate, 110g propylene glycol and 70g glycerol, mixed dissolution evenly becomes paste, final products.
Embodiment 3
In clean 2L container, add 130g Herba Asari, 90g Plumula Nelumbinis, the 160g Pseudobulbus Bletillae (Rhizoma Bletillae), 110g Pheretima, 90g Medulla Junci and 110g Indigo Naturalis, mix homogeneously, be ground into 650 order fine powders, add at last 60g Mel, 90g pectin, 50g Borneolum Syntheticum, 120g sodium laurylsulfate, 160g propylene glycol and 100g glycerol, mixed dissolution evenly becomes paste, final products.
Embodiment 4
In clean 2L container, add 85g Herba Asari, 85g Plumula Nelumbinis, the 150g Pseudobulbus Bletillae (Rhizoma Bletillae), 80g Pheretima, 65g Medulla Junci and 100g Indigo Naturalis, mix homogeneously, be ground into 700 order fine powders, add at last 50g Mel, 80g pectin, 40g Borneolum Syntheticum, 110g sodium laurylsulfate, 150g propylene glycol and 80g glycerol, mixed dissolution evenly becomes paste, final products.
Embodiment 5
In clean 2L container, add 90g Herba Asari, 60g Plumula Nelumbinis, the 140g Pseudobulbus Bletillae (Rhizoma Bletillae), 90g Pheretima, 70g Medulla Junci and 90g Indigo Naturalis, mix homogeneously, be ground into 750 order fine powders, add at last 40g Mel, 70g pectin, 35g Borneolum Syntheticum, 105g sodium laurylsulfate, 130g propylene glycol and 75g glycerol, mixed dissolution evenly becomes paste, final products.
Embodiment 6
In clean 2L container, add 100g Herba Asari, 55g Plumula Nelumbinis, the 135g Pseudobulbus Bletillae (Rhizoma Bletillae), 100g Pheretima, 80g Medulla Junci and 85g Indigo Naturalis, mix homogeneously, be ground into 680 order fine powders, add at last 55g Mel, 85g pectin, 25g Borneolum Syntheticum, 110g sodium laurylsulfate, 120g propylene glycol and 90g glycerol, mixed dissolution evenly becomes paste, final products.
The excellent results of above-mentioned toothpaste below is described by test.
Table 1 embodiment 1-6 is to the effective percentage result of the test of multiple oral disease
| Process | Oral ulcer (%) | Aphtha (%) | Toothache (%) | Halitosis (%) |
| Embodiment 1 | 98.36 | 93.55 | 83.10 | 100.00 |
| Embodiment 2 | 97.21 | 92.12 | 81.23 | 100.00 |
| Embodiment 3 | 98.56 | 92.96 | 84.20 | 100.00 |
| Embodiment 4 | 96.73 | 92.07 | 83.54 | 100.00 |
| Embodiment 5 | 95.15 | 91.21 | 82.33 | 100.00 |
| Embodiment 6 | 99.42 | 93.74 | 85.17 | 100.00 |
Table 1 shows: embodiment 1-6 all has preferably curative effect to oral ulcer, aphtha, toothache, halitosis, and embodiment 1 is better than embodiment 2, and embodiment 3 is better than embodiment 4, and embodiment 6 is better than embodiment 5.
Claims (5)
1. the toothpaste of a preventing canker sore is characterized in that containing the following material of percentage by weight: 6～15 parts of Herba Asaris, 4～10 parts of Plumula Nelumbinis, 11～17 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 6～13 parts of Pheretimas, 4～10 parts of Medulla Juncies, 6～13 parts of Indigo Naturaliss, 2～7 parts of Mel, 4～11 parts of pectin, 1～7 part of Borneolum Syntheticum, 5～13 parts of sodium laurylsulfates, 8～17 parts of propylene glycol, 4～11 parts of glycerol.
2. the toothpaste of a kind of preventing canker sore as claimed in claim 1 is characterized in that containing: 8～13 parts of Herba Asaris, 5～9 parts of Plumula Nelumbinis, 13～16 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 7～11 parts of Pheretimas, 5～9 parts of Medulla Juncies, 7～11 parts of Indigo Naturaliss, 3～6 parts of Mel, 5～9 parts of pectin, 2～5 parts of Borneolum Syntheticums, 8～12 parts of sodium laurylsulfates, 10～16 parts of propylene glycol, 6～10 parts of glycerol.
3. the toothpaste of a kind of preventing canker sore as claimed in claim 1 is characterized in that containing: 10～12 parts of Herba Asaris, 6～7 parts of Plumula Nelumbinis, 14～15 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 8～10 parts of Pheretimas, 6～8 parts of Medulla Juncies, 8～9 parts of Indigo Naturaliss, 4～5 parts of Mel, 6～7 parts of pectin, 3～4 parts of Borneolum Syntheticums, 9～10 parts of sodium laurylsulfates, 12～14 parts of propylene glycol, 8～9 parts of glycerol.
4. the preparation method of the toothpaste of a kind of preventing canker sore as claimed in claim 1 is characterized in that may further comprise the steps:
1) takes by weighing the following material of weight ratio: 6～15 parts of Herba Asaris, 4～10 parts of Plumula Nelumbinis, 11～17 parts of the Pseudobulbus Bletillae (Rhizoma Bletillae)s, 6～13 parts of Pheretimas, 4～10 parts of Medulla Juncies, 6～13 parts of Indigo Naturaliss, 2～7 parts of Mel, 4～11 parts of pectin, 1～7 part of Borneolum Syntheticum, 5～13 parts of sodium laurylsulfates, 8～17 parts of propylene glycol, 4～11 parts of glycerol, for subsequent use;
2) with Herba Asari, Plumula Nelumbinis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Pheretima, Medulla Junci, Indigo Naturalis, mix homogeneously all is ground into 600-800 order fine powder, and is for subsequent use;
3) with step 2) Mel, pectin, Borneolum Syntheticum, sodium laurylsulfate, propylene glycol, the glycerol of gained fine powder and described ratio is mixed into paste, packing toothpaste.
5. the application of the toothpaste of a kind of preventing canker sore as claimed in claim 1 in the anti-treating dental ulcer of preparation, halitosis, aphtha, preparation for curing toothache.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210569474 CN103006531A (en) | 2012-12-25 | 2012-12-25 | Toothpaste capable of preventing oral ulcers, and preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210569474 CN103006531A (en) | 2012-12-25 | 2012-12-25 | Toothpaste capable of preventing oral ulcers, and preparation method and application thereof |
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| Publication Number | Publication Date |
|---|---|
| CN103006531A true CN103006531A (en) | 2013-04-03 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 201210569474 Pending CN103006531A (en) | 2012-12-25 | 2012-12-25 | Toothpaste capable of preventing oral ulcers, and preparation method and application thereof |
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| Country | Link |
|---|---|
| CN (1) | CN103006531A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3603616A4 (en) * | 2017-03-21 | 2020-12-02 | Well Stone Co. | Method for producing oral composition, and oral composition |
| CN112603965A (en) * | 2020-12-29 | 2021-04-06 | 青岛大学附属医院 | External mixed medicine for treating oral ulcer and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3603616A4 (en) * | 2017-03-21 | 2020-12-02 | Well Stone Co. | Method for producing oral composition, and oral composition |
| US11260022B2 (en) | 2017-03-21 | 2022-03-01 | Well Stone Co. | Method for producing oral composition, and oral composition |
| CN112603965A (en) * | 2020-12-29 | 2021-04-06 | 青岛大学附属医院 | External mixed medicine for treating oral ulcer and preparation method thereof |
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