CN103003288B - 具有修饰的亚基间键和/或端基的寡核苷酸类似物 - Google Patents
具有修饰的亚基间键和/或端基的寡核苷酸类似物 Download PDFInfo
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- CN103003288B CN103003288B CN201180034599.5A CN201180034599A CN103003288B CN 103003288 B CN103003288 B CN 103003288B CN 201180034599 A CN201180034599 A CN 201180034599A CN 103003288 B CN103003288 B CN 103003288B
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710590274.4A CN107353317A (zh) | 2010-05-28 | 2011-05-27 | 具有修饰的亚基间键和/或端基的寡核苷酸类似物 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34978310P | 2010-05-28 | 2010-05-28 | |
| US61/349,783 | 2010-05-28 | ||
| US36187810P | 2010-07-06 | 2010-07-06 | |
| US61/361,878 | 2010-07-06 | ||
| US38642810P | 2010-09-24 | 2010-09-24 | |
| US61/386,428 | 2010-09-24 | ||
| PCT/US2011/038459 WO2011150408A2 (en) | 2010-05-28 | 2011-05-27 | Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710590274.4A Division CN107353317A (zh) | 2010-05-28 | 2011-05-27 | 具有修饰的亚基间键和/或端基的寡核苷酸类似物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103003288A CN103003288A (zh) | 2013-03-27 |
| CN103003288B true CN103003288B (zh) | 2019-06-21 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180034599.5A Expired - Fee Related CN103003288B (zh) | 2010-05-28 | 2011-05-27 | 具有修饰的亚基间键和/或端基的寡核苷酸类似物 |
| CN201710590274.4A Pending CN107353317A (zh) | 2010-05-28 | 2011-05-27 | 具有修饰的亚基间键和/或端基的寡核苷酸类似物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710590274.4A Pending CN107353317A (zh) | 2010-05-28 | 2011-05-27 | 具有修饰的亚基间键和/或端基的寡核苷酸类似物 |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US8779128B2 (https=) |
| EP (1) | EP2576574A2 (https=) |
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