CN102984938A - 轻度认知障碍(mci)和阿尔茨海默氏症的治疗方法 - Google Patents
轻度认知障碍(mci)和阿尔茨海默氏症的治疗方法 Download PDFInfo
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- CN102984938A CN102984938A CN2010800680043A CN201080068004A CN102984938A CN 102984938 A CN102984938 A CN 102984938A CN 2010800680043 A CN2010800680043 A CN 2010800680043A CN 201080068004 A CN201080068004 A CN 201080068004A CN 102984938 A CN102984938 A CN 102984938A
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- Prior art keywords
- nifedipine
- approximately
- described method
- pharmaceutical composition
- lactam
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 0 *c(cc(*c(c(I)cc(CC(C(O)=O)N)c1)c1I)cc1I)c1O Chemical compound *c(cc(*c(c(I)cc(CC(C(O)=O)N)c1)c1I)cc1I)c1O 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
USPCT/US2010/034721 | 2010-05-13 | ||
PCT/US2010/034721 WO2010132671A1 (fr) | 2009-05-15 | 2010-05-13 | Traitement du trouble cognitif léger et de la maladie d'alzheimer |
PCT/US2010/057287 WO2011142778A1 (fr) | 2010-05-13 | 2010-11-18 | Traitement du tcl et de la maladie d'alzheimer |
Publications (1)
Publication Number | Publication Date |
---|---|
CN102984938A true CN102984938A (zh) | 2013-03-20 |
Family
ID=44923820
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2010800680043A Pending CN102984938A (zh) | 2010-05-13 | 2010-11-18 | 轻度认知障碍(mci)和阿尔茨海默氏症的治疗方法 |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP2568811A4 (fr) |
JP (1) | JP2013526518A (fr) |
CN (1) | CN102984938A (fr) |
AU (1) | AU2010353287A1 (fr) |
CA (1) | CA2799162A1 (fr) |
WO (1) | WO2011142778A1 (fr) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106177046A (zh) * | 2016-08-29 | 2016-12-07 | 杨添福 | 一种基于普立宁钾开发的神经认知障碍治疗药物及其制备方法 |
CN106636388A (zh) * | 2016-12-15 | 2017-05-10 | 湖南中能荆卫生物科技有限公司 | 用于亨廷顿病诊断的基因及其应用以及由其编码的蛋白和蛋白的应用 |
CN106645505A (zh) * | 2016-11-18 | 2017-05-10 | 中国医科大学 | 可实现glt‑1蛋白鉴定及绝对定量的试剂盒及测定方法 |
CN107022019A (zh) * | 2016-11-24 | 2017-08-08 | 台州学院 | 一种用于脑内降铁除自由基的多肽、制备方法与应用 |
CN108191966A (zh) * | 2018-01-11 | 2018-06-22 | 台州学院 | 一种含导肽可穿越血脑屏障螯合脑内铁降自由基的多肽 |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014182631A1 (fr) * | 2013-05-06 | 2014-11-13 | Baxter International Inc. | Traitement de sous-populations atteintes de la maladie d'alzheimer avec de l'immunoglobuline g rassemblée |
CA2937529A1 (fr) * | 2014-01-29 | 2015-08-06 | Bristol-Myers Squibb Company | Inhibiteurs d'aryl-lactame kinase |
CN113853382A (zh) * | 2019-01-07 | 2021-12-28 | 森纳生物科学公司 | 新型肽及其用途 |
JP7321017B2 (ja) * | 2019-07-17 | 2023-08-04 | 東海物産株式会社 | 機能性食品 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3917832A (en) * | 1971-05-28 | 1975-11-04 | Merck Patent Gmbh | Compositions comprising d-thyroxine and d-triiodothyronine |
CN1479616A (zh) * | 2000-11-21 | 2004-03-03 | 霍华德・齐克 | 使用1,4-二氢吡啶钙通道阻断剂治疗疱疹神经病毒病症 |
US20100029654A1 (en) * | 2006-03-23 | 2010-02-04 | Mount Sinai School Of Medicine | Cardiovascular compositions and use of the same for the treatment of alzheimer's disease |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8002A (en) * | 1851-03-25 | Upright pianoforte | ||
AU744179B2 (en) * | 1998-04-08 | 2002-02-14 | Oregon Health Sciences University | Enhancement of cellular gallium uptake |
US6489319B2 (en) * | 1999-08-16 | 2002-12-03 | Revaax Pharmaceuticals, Llc | Neurotherapeutic use of carboxypeptidase inhibitors |
US20080026081A1 (en) * | 2003-11-21 | 2008-01-31 | Axel Unterbeck | Methods of Treatment Using (+)-Isopropyl 2-Ethoxyethyl-4-(2-Chloro-3-Cyano-Phenyl)-1,4-Dihydro-2,6-Dimethyl-Pyridine-3,5-Dicarboxylate |
EP1874311B1 (fr) * | 2005-04-15 | 2011-10-05 | Research & Innovation S.p.A. | Methode pour prevenir, retarder ou inverser la progression de pathologies associees a un depot amyloide anormal |
EP1955698B1 (fr) * | 2005-12-02 | 2013-10-30 | Mochida Pharmaceutical Co., Ltd. | Agent preventif/therapeutique contre la demence d'alzheimer |
CA2648243C (fr) * | 2006-04-11 | 2015-12-22 | Shaker A. Mousa | Nanoparticule et formes polymeres d'analogues et d'antagonistes de l'hormone thyroidienne et leurs formulations |
US20080293712A1 (en) * | 2007-03-05 | 2008-11-27 | Wyeth | Benzo[C][2,7]Naphtyridine Derivatives, Methods of Making Thereof and Methods of Use Thereof |
WO2010034110A1 (fr) * | 2008-09-25 | 2010-04-01 | Merck Frosst Canada Ltd. | Dérivés de bêta-carboline sulfonylurée en tant qu’antagonistes du récepteur d’ep4 |
TW201103907A (en) * | 2009-03-20 | 2011-02-01 | Lundbeck & Co As H | Amide derivatives as neuropeptide Y5 receptor ligands |
-
2010
- 2010-11-18 CA CA2799162A patent/CA2799162A1/fr not_active Abandoned
- 2010-11-18 CN CN2010800680043A patent/CN102984938A/zh active Pending
- 2010-11-18 EP EP10851531.3A patent/EP2568811A4/fr not_active Withdrawn
- 2010-11-18 JP JP2013510067A patent/JP2013526518A/ja active Pending
- 2010-11-18 WO PCT/US2010/057287 patent/WO2011142778A1/fr active Application Filing
- 2010-11-18 AU AU2010353287A patent/AU2010353287A1/en not_active Abandoned
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3917832A (en) * | 1971-05-28 | 1975-11-04 | Merck Patent Gmbh | Compositions comprising d-thyroxine and d-triiodothyronine |
CN1479616A (zh) * | 2000-11-21 | 2004-03-03 | 霍华德・齐克 | 使用1,4-二氢吡啶钙通道阻断剂治疗疱疹神经病毒病症 |
US20100029654A1 (en) * | 2006-03-23 | 2010-02-04 | Mount Sinai School Of Medicine | Cardiovascular compositions and use of the same for the treatment of alzheimer's disease |
Non-Patent Citations (1)
Title |
---|
HENK DE VRIES ET AL.: "Photoreactivity of nifedipine in vitro and in vivo", 《JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B: BIOLOGY》, vol. 43, 31 December 1998 (1998-12-31), pages 218 * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106177046A (zh) * | 2016-08-29 | 2016-12-07 | 杨添福 | 一种基于普立宁钾开发的神经认知障碍治疗药物及其制备方法 |
CN106645505A (zh) * | 2016-11-18 | 2017-05-10 | 中国医科大学 | 可实现glt‑1蛋白鉴定及绝对定量的试剂盒及测定方法 |
CN107022019A (zh) * | 2016-11-24 | 2017-08-08 | 台州学院 | 一种用于脑内降铁除自由基的多肽、制备方法与应用 |
CN106636388A (zh) * | 2016-12-15 | 2017-05-10 | 湖南中能荆卫生物科技有限公司 | 用于亨廷顿病诊断的基因及其应用以及由其编码的蛋白和蛋白的应用 |
CN108191966A (zh) * | 2018-01-11 | 2018-06-22 | 台州学院 | 一种含导肽可穿越血脑屏障螯合脑内铁降自由基的多肽 |
CN108191966B (zh) * | 2018-01-11 | 2020-10-27 | 桂林医学院 | 一种含导肽可穿越血脑屏障螯合脑内铁降自由基的多肽 |
Also Published As
Publication number | Publication date |
---|---|
CA2799162A1 (fr) | 2011-11-17 |
JP2013526518A (ja) | 2013-06-24 |
WO2011142778A1 (fr) | 2011-11-17 |
EP2568811A1 (fr) | 2013-03-20 |
EP2568811A4 (fr) | 2014-03-12 |
AU2010353287A1 (en) | 2012-11-29 |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130320 |