CN102940251B - Health-care food for reducing blood sugar and blood fat - Google Patents

Health-care food for reducing blood sugar and blood fat Download PDF

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CN102940251B
CN102940251B CN201210472614.0A CN201210472614A CN102940251B CN 102940251 B CN102940251 B CN 102940251B CN 201210472614 A CN201210472614 A CN 201210472614A CN 102940251 B CN102940251 B CN 102940251B
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parts
blood
health food
health
blood sugar
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CN102940251A (en
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许伯宗
许羿
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Abstract

The invention discloses a health-care food for reducing blood sugar and blood fat. The health-care food for reducing the blood sugar and the blood fat is characterized by comprising, by weight, hawthorn 20-50 parts, bitter gourd 20-50 parts, black soya bean 10-30 parts, medlar 10-30 parts, pumpkin 10-20 parts, Chinese yam 10-20 parts and poria cocos 5-10 parts. The health-care food for reducing the blood sugar and the blood fat is unique and scientific in formula, is made from natural foods, is safe and non-toxic, contains a large amount of amino acid, vegetable protein, mineral elements and the like, and can reduce blood sugar, the blood fat, blood viscidity and strengthen immunity of the organism after long-term taking.

Description

A kind of health food of reducing blood sugar and blood fat
Technical field
The present invention relates to a kind of health food, be specifically related to a kind of hypoglycemic and health food blood fat reducing function that has, belong to health product technology field.
Background technology
Along with the increase of living standard and operating pressure, the people of hyperglycaemia high fat of blood is more and more at present.Hyperglycaemia refers to fasting blood-glucose higher than 4.0-6.1mmol/L or two hours blood glucoses are higher than the situation of normal range (NR) 7.8mmol/L after the meal, and blood sugar continues to increase and will cause the diseases such as diabetes, atherosclerotic, apoplexy, heart disease.According to statistics, China glycosuria patient crosses 10,000,000, and within 40 years old, above crowd's incidence of disease is up to 2.53%.Diabetes do not heal all the life, can only lean on for a long time the stable treatment of medicine, take all the year round antidiabetic drug and easily cause toxicity accumulation, infringement liver, kidney, insulin injection is somewhat expensive not only, also can make antibody produce, accept for a long time bolus insulin and can produce hyperinsulinemia, vascular endothelial cell injury, makes its basement membrane thickened, promotes microthrombus to form.
Hyperlipemia is a kind of systemic disease, refers to that T-CHOL in blood (TC) and/or triglycerides (TG) are too high or HDL-C (HDL-C) is too low, and modern medicine is referred to as dyslipidemia.Lipid is insoluble or be slightly soluble in water, must with lipoprotein form, exist with combined with protein, and therefore, hyperlipemia is conventionally also referred to as hyperlipoprotememia.High fat of blood can promote the generation of the illnesss such as hypertension, diabetes, fatty liver, cirrhosis, endangers huge.
Hyperglycaemia, high fat of blood can make blood be height coagulated state late period, impel the heart, brain, kidney, retina, microangiopathies, seriously jeopardize patient's life, so hyperglycaemia and high fat of blood one need after diagnosing treatment in time and control, in order to avoid aggravation or deterioration.At present, have the medicine of a lot of hypoglycemics, lipopenicillinase, numerous in variety, curative effect differs.
Summary of the invention
The health food that the object of this invention is to provide a kind of reducing blood sugar and blood fat, this food health, safety, have no side effect, and reducing blood sugar and blood fat is effective.
The present invention is achieved by the following measures:
A health food for reducing blood sugar and blood fat, is characterized in that comprising the raw material of following weight portion: hawthorn 20-50 part, balsam pear 20-50 part, black soya bean 10-30 part, matrimony vine 10-30 part, pumpkin 10-20 part, Chinese yam 10-20 part, Poria cocos 5-10 part.
In above-mentioned health food, preferably include the raw material of following weight portion: 30 parts of hawthorn, 30 parts, balsam pear, 25 parts, black soya bean, 25 parts of matrimony vines, 15 parts, pumpkin, 15 parts of Chinese yams, 6 parts, Poria cocos.
Health food preparation of the present invention is simple, and each raw material is mixed, and wears into fine powder, sterilizing, packing.
Inventor is through years of researches and summary, obtained the health food that the present invention has reducing blood lipid hypoglycemic activity, this food formula is healthy, safety, wherein contain the compositions such as vegetable protein, amino acid, can promote the release of insulin, also contain the cation that calcium, magnesium, potassium, zinc, chromium etc. form the prothetic group of body various metals enzyme, the biosynthesis of insulin and release are had to good catalytic action.Scientific formulation of the present invention, long-term use can reduce blood sugar and blood fat, improves high blood coagulation state, substitute or the alternative antidiabetic drug of part or lipid lowerers, be the health food of a kind of green, safety.
In formula, each raw material effect is as follows:
Hawthorn, the effect with stomach strengthening and digestion promoting, tonifying spleen, in addition, modern study shows, in hawthorn, contain the compositions such as flavonoids, organic acid, triterpenes, vitamin C, carrotene, there is hemangiectasis, cardiac stimulant, increase CF, improve heart vigor, stimulating central nervous system system, reduce blood pressure and cholesterol, softening blood vessel, reducing blood lipid, fall blood sticky, increase the effects such as pancreas islet infusate flow.
Balsam pear, bitter, modern medicine study discovery, balsam pear, containing compositions such as Charantin, serotonin, glutamic acid, alanine, palmitic acid, leukotrienes, oleic acid and vitamin B1s, can reduce blood sugar, and diabetes are had to good preventive and therapeutic effect.
Black soya bean, have another name called black beans, black soya bean, the sweet property of taste is flat, nutritious black bean is abundant, contain the multiple nutritional components such as protein, aliphatic acid, vitamin, saponin(e, in addition, isoflavones and trace element are as all very high in the content of zinc, copper, magnesium, molybdenum, selenium, fluorine etc., extremely important to delaying human body caducity, reduction blood viscosity etc.Current research shows, black soya bean has the effect of reducing blood lipid, anti-oxidant, skin maintenance.
Matrimony vine, energy qi-restoratives production of sperm, nourishing the liver, nourshing kidney, moistening lung, be rich in the multiple nutritional components such as matrimony vine proteoglycan, vitamin C, phosphorus, iron, choline, research shows, that matrimony vine has is hypoglycemic, AFL, the effect such as hypotensive, antitumor, can also delay senility, antifatigue, improve the health.
Pumpkin, has clearing heat and promoting diuresis, moistening lung qi-benefitting, improves the effect of kidney blood flow, contains starch, polysaccharide, several amino acids, activated protein, carotenoid and various trace elements, can improve body's immunity, reduces blood pressure and blood sugar.
Chinese yam, there is tonifying spleen nourishing the stomach, the effect of the beneficial lung that promotes the production of body fluid, the puckery essence of kidney tonifying, wherein be rich in the compositions such as a large amount of protein, B family vitamin, vitamin C, vitamin E, glucose, crude protein amino acid, bile alkaline, allantoin, can prevent the abnormal and artery sclerosis of Human Lipid Metabolism, to safeguarding that insulin normal function also has certain effect, also there is the health-care effect such as strengthen immunity, beneficial heart and tranquilizing mind, delay senility.
Poria cocos, property slightly sweet flavor is flat, has the effect of eliminating dampness and diuresis, strengthening the spleen and stomach, antitoxic heart-soothing and sedative, contains a large amount of triterpene compounds and polysaccharide, and pachyman is wherein the special synergist of cytotoxic T lymphocyte, can increase immunity of organisms.
The present invention is according to the traditional Chinese medical science pathogenesis of hyperglycaemia and high fat of blood, in conjunction with modern medicine study, selecting hawthorn, balsam pear, black soya bean, matrimony vine, pumpkin, Chinese yam, Poria cocos is raw material, through the collaborative compatibility between them, play the effect of enriching yin and nourishing kidney, promoting blood circulation and removing blood stasis, tonifying middle-Jiao and Qi, clearing heat and promoting diuresis, righting reinforcing, fundamentally reduce blood sugar and blood fat, improve high blood coagulation state.
Further, in order to improve reducing blood sugar and blood fat effect, in the present invention's formula, also can add peanut, the root of kudzu vine, konjaku, stir-fry semen armeniacae amarae composition.Peanut contains vitamin E and zinc, can strengthen memory, anti-aging, skin care, also contains vitamin C, can reduce cholesterol, contributes to prevent and treat artery sclerosis, hypertension and coronary heart disease.In the root of kudzu vine, containing a large amount of flavonoids and Puerarin, have reducing blood lipid, hypoglycemic activity, treatment hyperglycaemia, high fat of blood illness have significant curative effect.Konjaku, You Ming Amorphophalus rivieri, low-heat, low fat, low sugar, contain 16 seed amino acids, ten kinds of mineral trace elements and abundant food fiber, and diabetes, hypertension are had to special efficacy.Semen armeniacae amarae, containing compositions such as amygdalin (amygdalin), emulsin, amygdalase, soluble proteins, has hypoglycemic, effect for reducing blood fat.Increase after new composition, formula consists of (weight portion): hawthorn 20-50 part, balsam pear 20-50 part, black soya bean 10-30 part, matrimony vine 10-30 part, pumpkin 10-20 part, Chinese yam 10-20 part, Poria cocos 5-10 part, peanut 15-20 part, root of kudzu vine 10-20 part, konjaku 10-20 part, stir-fry semen armeniacae amarae 1-5 part, preferably (weight portion): 30 parts of hawthorn, 30 parts, balsam pear, 25 parts, black soya bean, 25 parts of matrimony vines, 15 parts, pumpkin, 15 parts of Chinese yams, 6 parts, Poria cocos, 16 parts of peanuts, 15 parts of the roots of kudzu vine, 15 parts of konjakus, 2 parts of stir-fry semen armeniacae amaraes.
The present invention fill a prescription uniqueness, science, choosing natural food is raw material, safe, nontoxic, contains a large amount of amino acid, vegetable protein, mineral element etc., long-term taking energy hypoglycemic, lipopenicillinase, fall blood sticky, strengthen immunity of organisms.
The specific embodiment
Below by specific embodiment, the present invention will be further elaborated, should be understood that, following explanation is only in order to explain the present invention, its content is not limited.If no special instructions, following raw material is weight portion.
embodiment 1
Take 30 parts of hawthorn, 30 parts, balsam pear, 25 parts, black soya bean, 25 parts of matrimony vines, 15 parts, pumpkin, 15 parts of Chinese yams, 6 parts, Poria cocos, mix, wear into fine powder, cross 120 mesh sieves, then sterilizing, packing, obtain health food of the present invention.
embodiment 2
Take 20 parts of hawthorn, 50 parts, balsam pear, 10 parts, black soya bean, 30 parts of matrimony vines, 10 parts, pumpkin, 20 parts of Chinese yams, 5 parts, Poria cocos, mix, wear into fine powder, cross 120 mesh sieves, then sterilizing, packing, obtain health food of the present invention.
embodiment 3
Take 50 parts of hawthorn, 20 parts, balsam pear, 30 parts, black soya bean, 10 parts of matrimony vines, 20 parts, pumpkin, 10 parts of Chinese yams, 10 parts, Poria cocos, mix, wear into fine powder, cross 120 mesh sieves, then sterilizing, packing, obtain health food of the present invention.
embodiment 4
Take 30 parts of hawthorn, 30 parts, balsam pear, 25 parts, black soya bean, 25 parts of matrimony vines, 15 parts, pumpkin, 15 parts of Chinese yams, 6 parts, Poria cocos, 16 parts of peanuts, 15 parts of the roots of kudzu vine, 15 parts of konjakus, fry 2 parts of semen armeniacae amaraes, mix, wear into fine powder, cross 120 mesh sieves, then sterilizing, packing, obtain health food of the present invention.
embodiment 5
Take 20 parts of hawthorn, 50 parts, balsam pear, 10 parts, black soya bean, 30 parts of matrimony vines, 10 parts, pumpkin, 20 parts of Chinese yams, 5 parts, Poria cocos, 20 parts of peanuts, 10 parts of the roots of kudzu vine, 20 parts of konjakus, fry 1 part of semen armeniacae amarae, mix, wear into fine powder, cross 120 mesh sieves, then sterilizing, packing, obtain health food of the present invention.
embodiment 6
Take 50 parts of hawthorn, 20 parts, balsam pear, 30 parts, black soya bean, 10 parts of matrimony vines, 20 parts, pumpkin, 10 parts of Chinese yams, 10 parts, Poria cocos, 15 parts of peanuts, 20 parts of the roots of kudzu vine, 10 parts of konjakus, fry 5 parts of semen armeniacae amaraes, mix, wear into fine powder, cross 120 mesh sieves, then sterilizing, packing, obtain health food of the present invention.
embodiment 1 take below as example, the effect of research health food of the present invention
one, treatment group case chooses
From this city hospital, choose 100 routine maturity-onset diabetes patients, all patient's fasting blood-glucoses are all greater than 7.0mmol/L, male 46 examples wherein, female's 54 examples, 27~70 years old age, course of disease half a year~35 year, I type person 19 examples, II type person 81 examples.In addition,, in this 100 routine diabetic, there are 90 examples for diabetes and hyperlipidemia complications patient, patient Tch >5.7mmol/L, TG>1.8 mmol/L.This 100 routine patient is treatment group.
two, control group case chooses
Diabetic's 72 examples of selecting medical history, the state of an illness, age, sex and methods for the treatment of and treatment group to match are control group.
three, observational technique
3.1, parallel control:
(1) treatment group: on former treatment basis, according to conditions of patients situation, treat respectively according to methods for the treatment of described in 3.3.
(2) control group: conventional hypoglycemic, lipid-lowering therapy, hypoglycemic medicine wherein, kind usage and dosage and treatment group match, and lipid lowerers adopts import fenofibrate (fenofibrate capsules).
Above two groups: adopt same procedure, make regular check on fasting blood-glucose and blood fat, according to change of blood sugar, antidiabetic drug consumption gradually successively decreases.
3.2 own control
For eliminating individual difference, treatment group, before adding embodiment health food and after taking, is carried out own control, and observational technique is the same.
Three months observation periods, be a course for the treatment of January, counts three courses for the treatment of.
3.3 treatment group methods of treatments
Treatment group is used the health food of the embodiment of the present invention 1, a 5g, and every day 3 times, boiling water is taken after mixing it with water, the person of being in a bad way every day 4 times.
(1) alone: the state of an illness is lighter, on the basis of keeping on a diet, fasting blood-glucose is still 7.2-10mmol/L person, the antidiabetic drug of stopping using, alone health food;
(2) with OHA coupling: to the heavier diabetic of the state of an illness, the upper fasting blood-glucose > 11.1 mmol/L persons in basis keep on a diet, on former treatment basis, inactive lipid lowerers, add health food, according to change of blood sugar, tapering oral administration antidiabetic drug consumption gradually, health food of the present invention continues application, directly expires three courses for the treatment of.
(3) with insulin coupling: to patient with severe symptoms, the lipid lowerers of stopping using, insulin maintains former dosage, adds health food; Depending on the change of blood sugar insulin dosage that successively decreases gradually.
(4) the former patient with severe symptoms who has accepted insulin+Diamicron (gliclazide), on former treatment basis, adds health food, according to change of blood sugar, first remove gradually Diamicron, then the insulin dosage that successively decreases gradually, until blood sugar adopts maintenance dose after being effectively controlled.
four, observation index
4.1 fasting blood-glucose.
4.2 2 hours blood glucoses after the meal.
4.3 serum cholesterols, triglyceride and HDL.
4.4 some patients weres are surveyed FPI level and blood examination and T cell subsets.
4.5 routine urinalysis and urea nitrogen inspection.
4.6 routine blood tests and liver function chemical examination.
4.7 patient's ordinary circumstances and complication are improved situation.
five, curative effect judging standard
Effective: (1) symptom substantially disappears or obviously improves.
(2) more than fasting blood-glucose is treated front decline 30 %.
(3) drop to-~scholar of glucose in urine.
(4) former high fat of blood is reduced to normally.
(5) drug combination person, former OHA or insulin injection consumption are compared with front minimizing more than 50% and fall the above-mentioned standard that reaches on fasting blood glycolipid.
Effective: (1) clinical symptoms take a turn for the better.
(2) fasting blood-glucose is treated front decline 10-29%.
(3) drug combination person, OHA or insulin injection consumption, front decline 20-49%.
Invalid: general symptom is not improved, and blood sugar and rate and blood-lipid decreased do not reach above-mentioned standard.
six, observed result
After 6.1 3 months, use the treatment group patient clinical treatment results of health food of the present invention as shown in table 1 below.
As can be seen from Table 1, treatment group 100 examples, effective 52 examples, account for 52 %; Effective 43 examples, account for 43 %; Invalid 4 examples, account for 4 %; Total effective rate is 96%.
6.2 impacts of health food of the present invention on diabetic's fasting blood-glucose and 2h-plasma glucose, in Table 2 and table 3.
6.3 health foods of the present invention are to the diabetic with high fat of blood, and the variation of serum cholesterol, triglyceride and HDL, in Table 4 and table 5.
From table 4 and table 5, can find out that the patient of diabetes and hyperlipidemia complications takes after health food of the present invention than with front: serum cholesterol and triglyceride obviously decline, and HDL ratio is taken front obvious rising, its P< 0.01, difference highly significant.
6.4 treatment groups and control group are in the variation of the forward and backward hypoglycemic medicine consumption for the treatment of and fasting blood-glucose concentration, in Table 6
By table 6, can be found out: treatment group is substantially similar with hypoglycemic medicine (insulin and Diamicron) consumption to fasting blood-glucose concentration before control group Case treatment, its P>0.05, and after treatment, difference highly significant P<0.01.This explanation, treatment group adds health food of the present invention declines blood sugar, and antidiabetic drug minimizing 1/3~1/2, and control group declines blood sugar by increasing antidiabetic drug consumption, from two groups of blood sugar decline situations, treatment group is obviously better than control group.
Before and after 6.5 treatment groups and treatment of control group, fat-reducing medicament is used and the average change in concentration of blood fat, in Table 7
As can be seen from Table 7: treatment group and control group before treatment serum cholesterol and triglyceride mean concentration without significant difference, treatment group adds health food can not reach lipopenicillinase order ground by any lipid lowerers, and control group is to take expensive imported medicine fenofibrate just to make rate and blood-lipid decreased, after treatment, there were significant differences for two groups of blood fat, illustrates that health food lipid-lowering effect of the present invention is better than control group.
6.6 health foods are on the hemorheological impact of diabetic
Observe diabetic and merge Abnormal Blood Rheology (being hypercoagulative state) 43 examples, take 3 courses for the treatment of of health food of the present invention, wherein to recover diet normal for 25 examples, and 18 examples are clearly better.
The impact of 6.7 health foods on diabetic's immunologic function, in Table 8
As can be seen from Table 8: the OKT8 of the glycosuria patient before health food treatment of the present invention is significantly higher than Normal group, P<0.01, OKT4/ OKT8 ratio significantly reduces, P<0.01; Take after health food, these two recovery is roughly normal, and with the comparison of normal controls group, P>0.05, illustrates that health food of the present invention has the effect of enhanced machine body immunity function.
6.8 measure routine blood test, routine urinalysis and the liver function that 100 routine treatment group patients take health food of the present invention front and back, and result shows that health food of the present invention is without any side effects to liver, kidney and haemocyte.
6.9 measure 100 routine treatment group diabetics takes health food of the present invention front and back basal insulin level on an empty stomach, and after treatment, basal insulin is significantly improved before treating, and the results are shown in Table 9.
As can be seen from Table 9, diabetic takes health food of the present invention the release action that promotes endogenous insulin, and by own control, front and back treatment relatively has very significant difference, P<0.01.
seven, conclusion
By above-mentioned experimental study, can find out, the effect that health food of the present invention has significantly hypoglycemic, reducing blood lipid, improves high blood coagulation state, improves human body immune function, the generation of diabetes and complication thereof can be reduced, the consumption of lipid lowerers, reduction antidiabetic drug can be replaced.
In formula range of the present invention, the health food of gained has the effect that reduces blood sugar, blood fat, and action effect is difference slightly, respectively embodiment 1,2,4,5 is carried out to clinical trial below, observes their effect.
one, experimental subjects
Choose 196 diabetes and hyperlipidemia complications patients, patient's fasting blood-glucose is all greater than 7.0mmol/L, Tch >5.7mmol/L, TG>1.8 mmol/L, I type person 50 examples wherein, II type person 146 examples, man 110 people, female 86 people, age 25-60 year, ill time limit 1-20.
two, methods for the treatment of
Above-mentioned experimental subjects is divided into 4 groups, use respectively the health food of the embodiment of the present invention 1,2,4,5, the state of an illness is compared with the alone health food treatment of the lighter, the person of being in a bad way adopts the method treatment of health food and other drug coupling, and concrete methods for the treatment of is identical with methods for the treatment of described in above-mentioned 3.3.5g of health food, every day 3 times, boiling water is taken after mixing it with water, the person of being in a bad way every day 4 times.
three, criterion of therapeutical effect
Effective: (1) symptom substantially disappears or obviously improves.
(2) more than fasting blood-glucose is treated front decline 30 %.
(3) drop to-~scholar of glucose in urine.
(4) former high fat of blood is reduced to normally.
(5) drug combination person, former OHA or insulin injection consumption are compared with front minimizing more than 50% and fall the above-mentioned standard that reaches on fasting blood glycolipid.
Effective: (1) clinical symptoms take a turn for the better.
(2) fasting blood-glucose is treated front decline 10-29%.
(3) drug combination person, OHA or insulin injection consumption, front decline 20-49%.
Invalid: general symptom is not improved, and blood sugar and rate and blood-lipid decreased do not reach above-mentioned standard.
four, treatment results
According to method of the present invention, treat 3 months continuously, its result is as follows.
As can be seen from the above table, the health food effect of embodiment 4 is best, and embodiment 1 is suitable with 5 effects, the effect relative mistake of embodiment 2 some.

Claims (1)

1. the health food of a reducing blood sugar and blood fat, it is characterized in that being made by the raw material of following weight portion: take 30 parts of hawthorn, 30 parts, balsam pear, 25 parts, black soya bean, 25 parts of matrimony vines, 15 parts, pumpkin, 15 parts of Chinese yams, 6 parts, Poria cocos, 16 parts of peanuts, 15 parts of the roots of kudzu vine, 15 parts of konjakus, fry 2 parts of semen armeniacae amaraes, mix, wear into fine powder, cross 120 mesh sieves, then sterilizing, packing, obtain health food; The usage of described health food is: 1 5g, every day 3 times, boiling water is taken after mixing it with water.
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CN105053897A (en) * 2015-07-02 2015-11-18 李秀飞 Blood sugar lowering food and making method thereof
CN105192601A (en) * 2015-09-13 2015-12-30 陈博 Food with health care function
CN107087791A (en) * 2016-06-30 2017-08-25 健糖(北京)健康管理有限公司 A kind of edible food compositions of confession diabetic population and its preparation technology
CN107582845A (en) * 2017-09-20 2018-01-16 魏红 A kind of Plant Powder for preventing and treating diabetes
CN107616491A (en) * 2017-09-21 2018-01-23 珠海霍普金斯医药研究院股份有限公司 A kind of functional food for being used to prevent and treat diabetes
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CN108420057A (en) * 2018-02-09 2018-08-21 刘明秋 A kind of drug, health food or food compositions with hypoglycemic effect
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