CN102885728A - Natural skincare agent material mainly containing Honeysuckle total flavonoids and preparation method of natural healthcare agent material - Google Patents

Natural skincare agent material mainly containing Honeysuckle total flavonoids and preparation method of natural healthcare agent material Download PDF

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Publication number
CN102885728A
CN102885728A CN201110204434XA CN201110204434A CN102885728A CN 102885728 A CN102885728 A CN 102885728A CN 201110204434X A CN201110204434X A CN 201110204434XA CN 201110204434 A CN201110204434 A CN 201110204434A CN 102885728 A CN102885728 A CN 102885728A
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total flavones
flos lonicerae
preparation
take
flos
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宋小锋
许平辉
姚光勤
马锋
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XINXIANG BIOTECHNOLOGY CO Ltd
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XINXIANG BIOTECHNOLOGY CO Ltd
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Abstract

The invention discloses a natural skincare agent material mainly containing Honeysuckle total flavonoids and a preparation method of the natural healthcare agent material, which aims at supplying an anti-aging, ultraviolet-resistant, whitening and skincare active factor with functions of scavenging free radicals and promoting skin cell metabolism from natural plants for the cosmetics industry. Main active components comprise the honeysuckle total flavonoids, Rhodiola total flavonoids, Glycyrrhiza total flavonoids and clove extracts, wherein proportions of the components are 20-50%, 10-40%, 10-40% and 5-35% respectively; the prepared skincare agent material has the advantages of reasonable prescription, convenience for use and good skincare effect without any toxic side effect. The novelty of the invention is characterized in that the preparation of a herbal skincare agent material with a synergistic effect optimizes and combines the four materials to obtain an ideal skincare effect and other beneficial effects.

Description

A kind of take the Flos Lonicerae total flavones as main natural skin care agent raw material and preparation method thereof
Technical field
The invention belongs to the daily cosmetics field.Relate to a kind of natural skin care agent raw material take the Flos Lonicerae total flavones as the master and preparation method thereof, purpose is defying age, removing free radical, promotion skin cell metabolism, anti-ultraviolet radiation, the whitening and skin-protecting active factors that a kind of natural plants source is provided for cosmetic industry.Specifically take the Flos Lonicerae total flavones as monarch, take rhodioside as minister, licoflavone is as assistant, Flos Caryophylli extract is for making, according to the traditional Chinese medical science " monarch, minister, help, the make " principles of formulating prescriptions, optimum organization, reasonable compatibility are made and are had antioxidation, remove free radical, promote skin cell metabolism, prevent the natural skin care agent raw material of skin oxidative damage, anti-ultraviolet radiation, whitening and bacteriostasis efficacy.
Technical background
Along with going deep into of medical research, consumers in general hold more careful attitude to the cosmetics that use the synthetics manufacturing, in recent years, making up product take the natural herb plant essence as main medicine is emerging products of cosmetic industry, its sales volume is just surpassing 10% speed increase with every year, especially in the skin anti-aging field.For the women, constantly use anti-aging face cream and skin-whitening product, will consist of ever-increasing cosmetics and consume large market.
Skin is to safeguard human life and healthy pith, directly contacts with extraneous, and be the first barrier of body, very easily be subject to the impact of environmental factors and cause damaging.The aging action that brings except the age, stress, pollution, sunlight and ultraviolet irradiation all are the major reasons that causes skin aging.Skin aging is mainly manifested in two aspects: the 1. skin formation wrinkle that follows the string gradually; 2. skin appearance produces the various mottles such as chloasma, senile plaque gradually.According to the free-radical theory of aging, in the process of skin aging, the radical pair skin injury is a key factor.The profound cause of skin aging comprises that also the metabolism of epidermal keratinocytes slows down, and dermal fibroblast increment split speed reduces.If something mass-energy reduces the generation of skin free radical, improve the activity of SOD, again Skin Cell is had certain proliferation function, skin histology is upgraded accelerate, collagen protein generates and increases, and protects the moisture of skin, thus slowing down skin aging effectively.
Flos Lonicerae (Lonicera Japonica Thunb) is the Caprifoliaceae woodbine, the effect such as that the Flos Lonicerae total flavones has is antibacterial, the removing to free radical, lipoid peroxidization resistant, antiinflammatory and spasmolytic.Radix Rhodiolae (R.rosea) is Crassulaceae perennial herb or shrub plant, the contained Total Flavones from Rhodiola sachalinensis of Radix Rhodiolae has resisting fatigue, anti-hypoxia, resisting microwave radiation, antiviral and to nervous system and metabolic dual regulation, but also is a kind of environmental adaptation medicine.Radix Glycyrrhizae (G.uralensis) is dicotyledonous leguminous plant, studies show that, licoflavone is a kind of good whitening composition, its whitening function mainly from it to the tyrosine enzymeinhibition and to the inhibitory action of dopachrome isomerase, the flavone of Radix Glycyrrhizae also has antiinflammatory, spasmolytic and antiacid effect, in addition because the conjugacy of the molecular structure of liquorice flavonoids compound has strong absorption to ultraviolet light and visible light.Flos Caryophylli (S.aramaticum) is the Myrtaceae syzygium species plant, the Flos Caryophylli blood circulation promoting, treatment skin ulcer and wound inflammation, the treatment scabies, improve coarse skin, and have pleasant aromatic odor, Flos Caryophylli can play the effect of the through diseased region of all medicines of guiding also as wetting agent and penetration enhancer in addition.
Summary of the invention
Main purpose of the present invention is that development is a kind of take the Flos Lonicerae total flavones as main natural skin care agent activated feedstock and preparation method thereof, and said preparation is applied in the cosmetics mainly as defying age, whitening and skin-protecting active factors.
Take the Flos Lonicerae total flavones as main natural skin care agent assembly: be to suppress the Flos Lonicerae of nonenzymatic glycosylation, removing carbonyl compound, removing free radical as monarch drug; To remove free radical antioxidative Radix Rhodiolae as ministerial drug, auxiliary Flos Lonicerae performance effect; Assistant with Radix Glycyrrhizae to tryrosinase and dopachrome isomery enzymeinhibition, antiinflammatory, spasmolytic, antiacid and to ultraviolet absorption; At last with Flos Caryophylli with moisturizing and short infiltration function for making medicine, reasonable compatibility.Said preparation has antioxidation, removes free radical, radioprotective, promotion skin cell metabolism, prevents the skin oxidative damage, reduces the melanin generation, the beauty functions such as slow down aging, and can give product with the distinctive delicate fragrance of Flos Caryophylli, also have, all have sterilization, bacteriostasis such as Flos Lonicerae, Flos Caryophylli etc., so can greatly reduce the use to chemical preservative behind the use said preparation, for the safety of product more a guarantee.Have broad application prospects in daily cosmetics fields such as nutrition moisturizing agent, skin care suncream, wrinkle resistance, whitening agent, facial milk cleanser, bath gel, beautiful skin emulsion, beautiful skin water.
Basic assembly and preparation method thereof: the present invention is as raw material take natural Flos Lonicerae, Radix Rhodiolae, Radix Glycyrrhizae, Flos Caryophylli, after adopting ethanol reflux extraction to extract crude flavonoid powder, Macroporous Adsorption Resin, membrance separation to remove pigment, concentrate drying, in addition namely to be able to the Flos Lonicerae total flavones be main natural skin care agent activated feedstock to reasonable compatibility.
Concrete steps: (1) takes by weighing Flos Lonicerae 1000g (amount can zoom in or out in proportion according to demand), 70% ethanol is extracting solution, liquid ratio 12mL/g, namely add 70% ethanol 12L, extraction time 1.2h, extract 80 ℃ of temperature, filter gained filtrate after extracting 2 times to be Flos Lonicerae total flavones crude extract; (2) Flos Lonicerae total flavones crude extract is through Macroporous Adsorption Resin; (3) after membrane separation technique is removed pigment and further making with extra care, namely get the Flos Lonicerae total flavones behind the concentrate drying.Take same step to extract and to get Total Flavones from Rhodiola sachalinensis, Radix Glycyrrhizae total flavones, Flos Caryophylli extract respectively.(4) take by weighing Flos Lonicerae total flavones 3-5g, Total Flavones from Rhodiola sachalinensis 2-4g, Radix Glycyrrhizae total flavones 2-4g, Flos Caryophylli extract 1-2g, mix homogeneously namely make take the Flos Lonicerae total flavones as main natural skin care agent activated feedstock, lucifuge low-temperature preservation.
Take the Flos Lonicerae total flavones in main natural skin care agent activated feedstock preparation process, Flos Lonicerae total flavones, Total Flavones from Rhodiola sachalinensis, Radix Glycyrrhizae total flavones and Flos Caryophylli extract can extract separately preparation, also can be mixed in proportion the extraction preparation by several raw materials, whole raw materials mixing or part material mixed extraction prepare extractive of general flavone and all can.
Best assembly: take by weighing Flos Lonicerae total flavones 4g, Total Flavones from Rhodiola sachalinensis 2.5g, Radix Glycyrrhizae total flavones 2g, Flos Caryophylli extract 1.5g, the ratio of Flos Lonicerae total flavones, Total Flavones from Rhodiola sachalinensis, Radix Glycyrrhizae total flavones and Flos Caryophylli extract is approximately 8: 5: 4: 3; Or take by weighing Flos Lonicerae 400g, Radix Rhodiolae 250g, Radix Glycyrrhizae 200g, Flos Caryophylli 150g (each raw material can zoom in or out in proportion according to demand), 70% ethanol is extracting solution, liquid ratio 12mL/g, namely add 70% ethanol 12L, extraction time 1.2h, extract 80 ℃ of temperature, extracts and filter afterwards gained filtrate for 2 times and be take the natural skin care agent activated feedstock crude extract of Flos Lonicerae total flavones as leading, crude extract is through Macroporous Adsorption Resin, after membrane separation technique was removed pigment and further making with extra care, concentrate drying namely got natural skin care agent activated feedstock.
Beneficial effect
Novelty of the present invention is to have synergistic Flos Lonicerae, the preparation of Radix Rhodiolae, Radix Glycyrrhizae, Flos Caryophylli compositions, optimum organization, reasonable compatibility.Said preparation has antioxidation, removes free radical, radioprotective, promotion skin cell metabolism, prevents the skin oxidative damage, reduces the melanin generation, the beauty functions such as slow down aging, and can give product with the distinctive delicate fragrance of Flos Caryophylli, also have, all have sterilization, bacteriostasis such as Flos Lonicerae, Flos Caryophylli etc. and replace the use of chemical preservative, for the safety of product more a guarantee.
Have the following advantages take the Flos Lonicerae total flavones as main natural skin care agent activated feedstock:
(1) all from natural plants, extract take effective ingredient Flos Lonicerae total flavones, Total Flavones from Rhodiola sachalinensis, Radix Glycyrrhizae total flavones and the Flos Caryophylli extract of Flos Lonicerae total flavones as main natural skin care agent activated feedstock, so said preparation has the characteristics of green, environmental protection, safety.
(2) according to the traditional Chinese medical science " monarch, minister, help, make " prescription thought, optimum organization, reasonable compatibility.Said preparation has antioxidation, removes free radical, radioprotective, promotion skin cell metabolism, prevents the beauty functions such as skin oxidative damage, whitening and slow down aging.
(3) Flos Lonicerae, Flos Caryophylli etc. all have sterilization, bacteriostasis, can reduce the use of chemical preservative when using said preparation to make cosmetics, for the safety of product more a guarantee.
The specific embodiment
In view of having antioxidation take the Flos Lonicerae total flavones as main natural skin care agent activated feedstock, remove free radical, radioprotective, promotion skin cell metabolism, preventing the beauty functions such as skin oxidative damage, whitening and slow down aging, meet simultaneously the security requirement as cosmetics additive, can be used as the functional component of defying age or whitening skin care product, be applied in the multiple daily cosmetics such as nutrition moisturizing agent, sun-proof skin care agent, wrinkle resistance, whitening agent, facial milk cleanser, bath gel, beautiful skin emulsion, beautiful skin water.
Embodiment one
Take by weighing Flos Lonicerae 1000g (amount can zoom in or out in proportion according to demand), 70% ethanol is extracting solution, liquid ratio 12mL/g, namely add 70% ethanol 12L, extraction time 1.2h extracts 80 ℃ of temperature, filters gained filtrate after extracting 2 times to be Flos Lonicerae total flavones crude extract; Flos Lonicerae total flavones crude extract is through Macroporous Adsorption Resin; Membrane separation technique namely gets the Flos Lonicerae total flavones after removing pigment and further making with extra care behind the concentrate drying.Take same step to extract and to get Total Flavones from Rhodiola sachalinensis, Radix Glycyrrhizae total flavones, Flos Caryophylli extract respectively; Take by weighing Flos Lonicerae total flavones 3-5g, Total Flavones from Rhodiola sachalinensis 2-4g, Radix Glycyrrhizae total flavones 2-4g, Flos Caryophylli extract 1-2g, mix homogeneously namely make take the Flos Lonicerae total flavones as main natural skin care agent activated feedstock.
Embodiment two
Take by weighing Flos Lonicerae 400g, Radix Rhodiolae 250g, Radix Glycyrrhizae 200g, Flos Caryophylli 150g (each raw material can zoom in or out in proportion according to demand), 70% ethanol is extracting solution, liquid ratio 12mL/g, namely add 70% ethanol 12L, extraction time 1.2h, extract 80 ℃ of temperature, extracts and filter afterwards gained filtrate for 2 times and be take the natural skin care agent activated feedstock crude extract of Flos Lonicerae total flavones as leading, crude extract is through Macroporous Adsorption Resin, after membrane separation technique was removed pigment and further making with extra care, it was main natural skin care agent activated feedstock that concentrate drying namely is able to the Flos Lonicerae total flavones.
What prepare can be applied in the cosmetics by following non-limiting examples again take the Flos Lonicerae total flavones as main natural skin care agent activated feedstock.
Embodiment three crease-resistant emulsions
Figure BSA00000541663000041
Embodiment four crease-resistant beautiful skin water
Figure BSA00000541663000042
Embodiment five nutrition cosmetic creams
Figure BSA00000541663000043
Figure BSA00000541663000051
Embodiment six slow down aging essences
Figure BSA00000541663000052
At last, it is also to be noted that what more than enumerate only is some specific embodiments of the present invention.Obviously, the invention is not restricted to above embodiment, many distortion can also be arranged.All distortion that the member of ordinary skill in the art can directly derive or associate from content disclosed by the invention all should be thought protection scope of the present invention.

Claims (5)

1. one kind take the Flos Lonicerae total flavones as main natural skin care agent raw material and preparation method thereof, and the active component that it is characterized in that this skin protectant raw material mainly is Flos Lonicerae total flavones, Total Flavones from Rhodiola sachalinensis, Radix Glycyrrhizae total flavones and Flos Caryophylli extract.
2. as claimed in claim 1 a kind of take the Flos Lonicerae total flavones as main natural skin care agent raw material and preparation method thereof, the ratio that it is characterized in that Flos Lonicerae total flavones in this skin protectant raw material is 20-50%; The ratio of Total Flavones from Rhodiola sachalinensis is 10-40%; The ratio of Radix Glycyrrhizae total flavones is 10-40%; The ratio of Flos Caryophylli extract is 5-35%.Best of breed is Flos Lonicerae total flavones 40%; The ratio of Total Flavones from Rhodiola sachalinensis is 25%; The ratio of Radix Glycyrrhizae total flavones is 20%; The ratio of Flos Caryophylli extract is 15%.
3. as claimed in claim 1 a kind of take the Flos Lonicerae total flavones as main natural skin care agent raw material and preparation method thereof, it is characterized in that the preparation method of this raw material is for taking by weighing Flos Lonicerae 1000g (amount can zoom in or out in proportion according to demand), 70% ethanol is extracting solution, liquid ratio 12mL/g, namely add 70% ethanol 12L, extraction time 1.2h extracts 80 ℃ of temperature, filters gained filtrate after extracting 2 times to be Flos Lonicerae total flavones crude extract; Flos Lonicerae total flavones crude extract is through Macroporous Adsorption Resin; Membrane separation technique namely gets the Flos Lonicerae total flavones after removing pigment and further making with extra care behind the concentrate drying.Take same step to extract and to get Total Flavones from Rhodiola sachalinensis, Radix Glycyrrhizae total flavones, Flos Caryophylli extract respectively; Take by weighing Flos Lonicerae total flavones 4g, Total Flavones from Rhodiola sachalinensis 2.5g, Radix Glycyrrhizae total flavones 2g, Flos Caryophylli extract 1.5g, mix homogeneously namely make take the Flos Lonicerae total flavones as main natural skin care agent activated feedstock.
4. as claimed in claim 1 a kind of take the Flos Lonicerae total flavones as main natural skin care agent activated feedstock and preparation method thereof, it is characterized in that take the Flos Lonicerae total flavones in main natural skin care agent activated feedstock preparation process, Flos Lonicerae total flavones, Total Flavones from Rhodiola sachalinensis, Radix Glycyrrhizae total flavones and Flos Caryophylli extract both can extract separately preparation, also can be mixed in proportion the extraction preparation by several raw materials, whole raw materials mixing or part material mixed extraction prepare extractive of general flavone and all can.
5. as claimed in claim 1 a kind of take the Flos Lonicerae total flavones as main natural skin care agent raw material and preparation method thereof, it is characterized in that this raw material according to different processing technique and the prescription can further make the cosmetics with given efficacy, multiple daily cosmetics such as crease-resistant emulsion, crease-resistant beautiful skin water, nutrition cosmetic cream, slow down aging essence, facial milk cleanser, sun-proof skin care agent, wrinkle resistance, whitening agent, bath gel.
CN201110204434XA 2011-07-21 2011-07-21 Natural skincare agent material mainly containing Honeysuckle total flavonoids and preparation method of natural healthcare agent material Pending CN102885728A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106038384A (en) * 2016-06-08 2016-10-26 马殿伟 Traditional Chinese medicine composition containing wild jujubes and used for sunscreen cosmetics
CN111317696A (en) * 2020-04-22 2020-06-23 兰州资源环境职业技术学院 Functional lipstick and preparation method thereof
CN112675103A (en) * 2019-10-18 2021-04-20 孙川 Day cream with multiple layers of sun-screening and skin-protecting functions

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1210730A (en) * 1998-07-21 1999-03-17 李政俭 Plant preparation and its preparing method
CN1424022A (en) * 2002-07-22 2003-06-18 游向东 Skin nourishing source
CN1436524A (en) * 2003-03-03 2003-08-20 杭州浙大力夫生物科技有限公司 Application of bamboo leaf general flavone as antisenility skin care factor in cosmetics
CN1597690A (en) * 2004-07-21 2005-03-23 叶利明 Enrichment method of rhodiola root glycoside compound
CN101530385A (en) * 2009-04-14 2009-09-16 北京工商大学 Flos caryophylli extract as well as preparation method and application thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1210730A (en) * 1998-07-21 1999-03-17 李政俭 Plant preparation and its preparing method
CN1424022A (en) * 2002-07-22 2003-06-18 游向东 Skin nourishing source
CN1436524A (en) * 2003-03-03 2003-08-20 杭州浙大力夫生物科技有限公司 Application of bamboo leaf general flavone as antisenility skin care factor in cosmetics
CN1597690A (en) * 2004-07-21 2005-03-23 叶利明 Enrichment method of rhodiola root glycoside compound
CN101530385A (en) * 2009-04-14 2009-09-16 北京工商大学 Flos caryophylli extract as well as preparation method and application thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106038384A (en) * 2016-06-08 2016-10-26 马殿伟 Traditional Chinese medicine composition containing wild jujubes and used for sunscreen cosmetics
CN112675103A (en) * 2019-10-18 2021-04-20 孙川 Day cream with multiple layers of sun-screening and skin-protecting functions
CN111317696A (en) * 2020-04-22 2020-06-23 兰州资源环境职业技术学院 Functional lipstick and preparation method thereof

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Application publication date: 20130123