CN102517282A - 一种富集分离内源转录因子及其复合物的方法及其专用转录因子串联结合序列 - Google Patents
一种富集分离内源转录因子及其复合物的方法及其专用转录因子串联结合序列 Download PDFInfo
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Images
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- G—PHYSICS
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
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Abstract
Description
TF | SPC | TF | SPC | TF | SPC |
ADNP | 11 | IRF5 | 16 | SFPI1 | 6 |
AHCTF1 | 20 | IRF6 | 12 | SIM2 | 1 |
AHR | 3 | IRF8 | 6 | SIX4 | 2 |
ARID1A | 45 | IRF9 | 16 | SIX5 | 1 |
ARID1B | 34 | JAZF1 | 2 | SKOR1 | 1 |
ARID2 | 11 | JUN | 9 | SMAD2 | 15 |
ARID5B | 34 | JUNB | 8 | SMAD4 | 3 |
ARNT | 10 | JUND | 41 | SMAD5 | 3 |
ARNTL | 301 | KLF12 | 6 | SMARCA1 | 41 |
ARNTL2 | 3 | KLF13 | 6 | SMARCA5 | 261 |
ASCL1 | 5 | KLF15 | 3 | SMARCC1 | 60 |
ATF1 | 87 | KLF3 | 3 | SMARCC2 | 228 |
ATF2 | 30 | KLF9 | 7 | SMARCE1 | 79 |
ATF7 | 63 | LIN28B | 1 | SOX13 | 4 |
ATOH1 | 1 | MAFB | 8 | SOX18 | 7 |
AW146020 | 1 | MAFG | 45 | SOX5 | 23 |
BACH1 | 39 | MAFK | 20 | SOX6 | 14 |
BACH2 | 7 | MAX | 120 | SOX8 | 6 |
BARHL2 | 4 | MAZ | 22 | SP1 | 13 |
BAZ2A | 9 | MEF2C | 24 | SP3 | 21 |
BAZ2B | 57 | MEF2D | 24 | SREBF1 | 4 |
BBX | 2 | MGA | 29 | SREBF2 | 2 |
BCL11B | 1 | MIER1 | 5 | SRF | 14 |
BCL6 | 5 | MITF | 1 | SSRP1 | 55 |
BHLHE40 | 48 | MLX | 372 | STAT1 | 636 |
BHLHE41 | 3 | MLXIP | 8 | STAT2 | 19 |
BPTF | 2 | MLXIPL | 438 | STAT3 | 1379 |
BZW1 | 8 | MNT | 34 | STAT5A | 35 |
C130039016RIK | 12 | MTA1 | 11 | STAT5B | 39 |
CARHSP1 | 5 | MTA2 | 108 | STAT6 | 6 |
CASZ1 | 1 | MTA3 | 9 | TADA2B | 1 |
CBFB | 7 | MXD1 | 2 | TBP | 34 |
CDC5L | 16 | MXD4 | 1 | TBX3 | 18 |
CEBPA | 56 | MXI 1 | 1 | TBX5 | 1 |
CEBPB | 73 | MYBL1 | 8 | TCF20 | 37 |
CEBPG | 17 | MYCN | 32 | TCF7L1 | 22 |
CEBPZ | 34 | MYT1L | 4 | TCF7L2 | 43 |
CHD7 | 44 | MZF1 | 1 | TCFAP4 | 25 |
CIC | 4 | NFAT5 | 32 | TCFCP2 | 102 |
CLOCK | 281 | NFATC1 | 81 | TCFCP2L1 | 10 |
CREB1 | 130 | NFATC2 | 7 | TCFEC | 3 |
CREB3L3 | 20 | NFATC3 | 56 | TEAD1 | 14 |
CREBL2 | 6 | NFE2L1 | 5 | TEAD3 | 18 |
CREM | 73 | NFE2L2 | 1 | TEAD4 | 1 |
CSDA | 287 | NFIA | 465 | TERF2 | 1 |
CSDE1 | 8 | NFIB | 514 | TFAM | 512 |
CTCF | 145 | NFIC | 482 | TFDP1 | 10 |
CTCFL | 1 | NFIL3 | 89 | TFDP2 | 9 |
CUX1 | 17 | NFIX | 706 | THRA | 6 |
DBP | 2 | NFKB1 | 230 | THRB | 93 |
DEAF1 | 4 | NFKB2 | 88 | TOX4 | 30 |
DMAP1 | 10 | NFKBIL1 | 3 | TSHZ1 | 1 |
DR1 | 5 | NFRKB | 82 | TSHZ3 | 1 |
DRAP1 | 38 | NFYA | 64 | TTF1 | 15 |
E2F1 | 1 | NFYB | 26 | TMLP1 | 2 |
E2F3 | 43 | NFYC | 110 | UBP1 | 404 |
E2F4 | 18 | NKX2-2 | 1 | UBTF | 717 |
E4F1 | 1 | NOC3L | 14 | USF1 | 114 |
EGR3 | 2 | NOC4L | 5 | USF2 | 115 |
ELF1 | 30 | NOTCH1 | 1 | VEZF1 | 47 |
ELF2 | 29 | NOTCH2 | 2 | WIZ | 1 |
ELF3 | 3 | NPAS2 | 8 | XBP1 | 20 |
ELF4 | 8 | NROB2 | 1 | YBX1 | 989 |
ELK3 | 20 | NR1D2 | 34 | YEATS4 | 3 |
ELK4 | 26 | NR1H2 | 39 | YY1 | 68 |
EP400 | 21 | NR1H3 | 104 | YY2 | 3 |
ERF | 25 | NR1H4 | 179 | ZBTB17 | 8 |
ERG | 42 | NR1I2 | 26 | ZBTB2 | 5 |
ESRRA | 210 | NR1I3 | 130 | ZBTB20 | 400 |
ESRRB | 11 | NR2C1 | 11 | ZBTB40 | 1 |
ESRRG | 69 | NR2C2 | 124 | ZBTB43 | 6 |
ETS1 | 3 | NR2F1 | 69 | ZBTB44 | 9 |
ETV3 | 1 | NR2F2 | 153 | ZBTB7A | 22 |
ETV6 | 25 | NR2F6 | 204 | ZBTB7B | 16 |
FAM171B | 2 | NR3C1 | 119 | ZDHHC17 | 2 |
FEZF1 | 1 | NR3C2 | 25 | ZFHX3 | 19 |
FLI1 | 21 | NR4A2 | 31 | ZFHX4 | 13 |
FOSL2 | 3 | NR4A3 | 12 | ZFP143 | 1 |
FOXA1 | 24 | NR5A2 | 5 | ZFP148 | 40 |
FOXA2 | 24 | NRF1 | 159 | ZFP184 | 1 |
FOXA3 | 12 | ONECUT1 | 92 | ZFP187 | 5 |
FOXF1A | 2 | ONECUT2 | 57 | ZFP189 | 1 |
FOXJ2 | 3 | ONECUT3 | 12 | ZFP191 | 2 |
FOXJ3 | 16 | PBX1 | 10 | ZFP219 | 11 |
FOXK1 | 151 | PBX2 | 16 | ZFP260 | 1 |
FOXK2 | 16 | PBX3 | 6 | ZFP263 | 4 |
FOXN3 | 7 | PDS5B | 102 | ZFP280B | 1 |
FOX01 | 30 | PHOX2B | 6 | ZFP281 | 11 |
FOX03 | 21 | PKNOX1 | 2 | ZFP319 | 4 |
FOX04 | 23 | PLAGL1 | 1 | ZFP362 | 3 |
FOX06 | 11 | PLAGL2 | 6 | ZFP367 | 2 |
FOXP1 | 117 | POU2F1 | 17 | ZFP382 | 1 |
FOXP2 | 2 | POU5F1 | 1 | ZFP384 | 10 |
FOXP4 | 48 | PPARA | 201 | ZFP42 | 4 |
FOXQ1 | 2 | PPARD | 7 | ZFP445 | 1 |
FOXS1 | 2 | PPARG | 29 | ZFP458 | 4 |
GABPA | 129 | PRDM1 | 2 | ZFP462 | 1 |
GATA4 | 12 | PRDM10 | 18 | ZFP512 | 27 |
GATA6 | 1 | PRDM15 | 1 | ZFP516 | 1 |
GATAD2A | 38 | PRDM16 | 18 | ZFP524 | 5 |
GATAD2B | 22 | PROX1 | 224 | ZFP536 | 3 |
GCFC1 | 35 | RARA | 144 | ZFP558 | 2 |
GLI1 | 5 | RARB | 82 | ZFP574 | 1 |
GLI3 | 1 | RARG | 111 | ZFP592 | 9 |
GM1862 | 3 | RB1 | 13 | ZFP628 | 1 |
GMEB1 | 10 | RBL1 | 18 | ZFP629 | 1 |
GMEB2 | 4 | RBL2 | 51 | ZFP641 | 1 |
HAND2 | 1 | RBPJ | 58 | ZFP644 | 1 |
HES1 | 5 | REL | 28 | ZFP652 | 8 |
HHEX | 14 | RELA | 94 | ZFP655 | 1 |
HINFP | 1 | RELB | 5 | ZFP687 | 5 |
HIVEP2 | 1 | REPIN1 | 6 | ZFP771 | 8 |
HLX | 1 | REST | 10 | ZFP775 | 2 |
HMB0X1 | 8 | RFX1 | 62 | ZFP777 | 1 |
HMG20A | 34 | RFX2 | 12 | ZFP787 | 1 |
HMG20B | 12 | RFX3 | 8 | ZFP800 | 18 |
HMGA1 | 106 | RFX5 | 13 | ZFP819 | 1 |
HMGA2 | 48 | RFX7 | 1 | ZFP825 | 2 |
HMGB2 | 89 | RFXANK | 4 | ZFP827 | 1 |
HMGB3 | 87 | RLF | 1 | ZFP828 | 4 |
HNF1A | 445 | RORA | 4 | ZFPM1 | 8 |
HNF1B | 53 | RORC | 20 | ZHX1 | 11 |
HNF4A | 631 | RREB1 | 132 | ZHX2 | 19 |
HNF4G | 7 | RUNX1 | 4 | ZHX3 | 18 |
HSF4 | 10 | RUNX3 | 2 | ZIC3 | 1 |
IKZF1 | 6 | RXRA | 809 | ZKSCAN1 | 2 |
IKZF5 | 1 | RXRB | 410 | ZKSCAN14 | 4 |
IRF1 | 5 | RXRG | 160 | ZKSCAN3 | 3 |
IRF2 | 88 | SALL1 | 10 | ZNF512B | 1 |
IRF3 | 59 | SATB2 | 2 | ZSCAN2 | 2 |
IRF5 | 16 | ZZZ3 | 1 |
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US13/730,177 US8846884B2 (en) | 2011-12-30 | 2012-12-28 | Method for enrichment and isolation of endogenous transcription factor and complexes thereof and corresponding tandem arrays of concatenated transcription factor response elements |
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CN103293321A (zh) * | 2013-05-27 | 2013-09-11 | 北京大学 | 一种检测dna损伤诱导的早期核仁应激的试剂盒及其应用 |
CN103571847A (zh) * | 2012-07-26 | 2014-02-12 | 汕头大学·香港中文大学联合汕头国际眼科中心 | Foxc1基因突变体及其应用 |
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