CN102459347A - 双重可变结构域免疫球蛋白及其用途 - Google Patents

双重可变结构域免疫球蛋白及其用途 Download PDF

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Publication number
CN102459347A
CN102459347A CN2010800293337A CN201080029333A CN102459347A CN 102459347 A CN102459347 A CN 102459347A CN 2010800293337 A CN2010800293337 A CN 2010800293337A CN 201080029333 A CN201080029333 A CN 201080029333A CN 102459347 A CN102459347 A CN 102459347A
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seq
binding
antigen
antibody
amino acid
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Chinese (zh)
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T.哈于尔
J.刘
G.A.金斯伯里
E.B.雷利
S.E.摩根-拉普
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AbbVie Inc
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Abbott GmbH and Co KG
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CN2010800293337A 2009-05-01 2010-04-30 双重可变结构域免疫球蛋白及其用途 Pending CN102459347A (zh)

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US17471109P 2009-05-01 2009-05-01
US61/174711 2009-05-01
PCT/US2010/033231 WO2010127284A2 (en) 2009-05-01 2010-04-30 Dual variable domain immunoglobulins and uses thereof

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EP (1) EP2425010A4 (cg-RX-API-DMAC7.html)
JP (1) JP2012525155A (cg-RX-API-DMAC7.html)
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Cited By (3)

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CN105209076A (zh) * 2013-03-15 2015-12-30 阿布维公司 抗体药物偶联物(adc)纯化
CN113234165A (zh) * 2021-05-07 2021-08-10 暨南大学 EpCAM的改造的结合蛋白及其应用
CN113354715A (zh) * 2021-05-07 2021-09-07 暨南大学 Egfr的改造的结合蛋白及其应用

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US8962803B2 (en) 2008-02-29 2015-02-24 AbbVie Deutschland GmbH & Co. KG Antibodies against the RGM A protein and uses thereof
BRPI0910482A2 (pt) 2008-04-29 2019-09-24 Abbott Lab imunoglobinas de domínio variável duplo e usos das mesmas
EP2297209A4 (en) 2008-06-03 2012-08-01 Abbott Lab IMMUNOGLOBULINS WITH TWO VARIABLE DOMAINS AND USES THEREOF
AU2009256246B2 (en) 2008-06-03 2013-07-18 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
BRPI0915448A2 (pt) 2008-07-08 2015-11-10 Abbott Lab imunoglobulinas de domínio variável duplo para prostaglandina e2 e usos das mesmas
JP5587975B2 (ja) * 2009-04-07 2014-09-10 ロシュ グリクアート アクチェンゲゼルシャフト 二重特異的抗−ＥｒｂＢ−３／抗−ｃ−Ｍｅｔ抗体
CN102741288B (zh) 2009-08-29 2015-08-19 Abbvie公司 治疗用dll4结合蛋白
JP2013503607A (ja) * 2009-09-01 2013-02-04 アボット・ラボラトリーズ 二重可変ドメイン免疫グロブリンおよびその使用
MX2012004415A (es) * 2009-10-15 2012-05-08 Abbott Lab Inmunoglobulinas de dominio variable doble y usos de las mismas.
UY32979A (es) 2009-10-28 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
EP2510001B1 (en) 2009-12-08 2015-12-02 AbbVie Deutschland GmbH & Co KG Monoclonal antibodies against the rgm a protein for use in the treatment of retinal nerve fiber layer degeneration
KR101853278B1 (ko) 2010-03-02 2018-05-02 애브비 인코포레이티드 치료학적 ｄｌｌ４ 결합 단백질
JP2013537415A (ja) 2010-08-03 2013-10-03 アッヴィ・インコーポレイテッド 二重可変ドメイン免疫グロブリンおよびその使用
CN103260639A (zh) 2010-08-26 2013-08-21 Abbvie公司 双重可变结构域免疫球蛋白及其用途
MX2013010011A (es) 2011-03-01 2014-10-24 Amgen Inc Agentes de unión biespecífica.
CN103635490A (zh) 2011-06-16 2014-03-12 诺瓦提斯公司 用作治疗剂的可溶性蛋白
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