CN102448987B - 一种抗vegf的单克隆抗体及含有该抗体的药物组合物 - Google Patents
一种抗vegf的单克隆抗体及含有该抗体的药物组合物 Download PDFInfo
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CN201080018409.6A CN102448987B (zh) | 2009-08-28 | 2010-08-27 | 一种抗vegf的单克隆抗体及含有该抗体的药物组合物 |
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JP5823858B2 (ja) * | 2008-03-26 | 2015-11-25 | エピトミクス インコーポレーティッド | 抗vegf抗体 |
CN102002104A (zh) | 2009-08-28 | 2011-04-06 | 江苏先声药物研究有限公司 | 一种抗vegf的单克隆抗体及含有该抗体的药物组合物 |
CN102875676B (zh) * | 2011-07-13 | 2014-11-05 | 无锡天演生物技术有限公司 | 全人源抗人vegf单抗分子及其应用 |
CN103417965B (zh) * | 2012-05-17 | 2018-04-13 | 江苏先声药业有限公司 | 一种含有抗vegf抗体的药物组合物 |
CN103417964A (zh) * | 2012-05-17 | 2013-12-04 | 江苏先声药物研究有限公司 | 一种抗vegf抗体的用途 |
US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
AU2015376558B9 (en) * | 2015-01-06 | 2021-07-01 | Zhuhai Essex Bio-Pharmaceutical Co., Ltd. | Anti-VEGF antibody |
EP3973977A1 (en) | 2015-03-31 | 2022-03-30 | Ildong Pharm Co., Ltd. | Pharmaceutical composition for preventing and treating eye diseases, containing, as active ingredient, fusion protein in which tissue-penetrating peptide and anti-vascular endothelial growth factor preparation are fused |
KR102128966B1 (ko) | 2015-09-01 | 2020-07-01 | 일동제약(주) | 종양 투과성 펩타이드와 항-신생혈관생성 제제가 융합된 융합단백질을 유효성분으로 포함하는 암 또는 혈관신생관련 질환 예방 및 치료용 약학적 조성물 |
CA2998343A1 (en) * | 2015-09-14 | 2017-03-23 | Galaxy Biotech Llc | Highly potent monoclonal antibodies to angiogenic factors |
AU2016381964B2 (en) | 2015-12-30 | 2024-02-15 | Kodiak Sciences Inc. | Antibodies and conjugates thereof |
US11008387B2 (en) | 2016-01-06 | 2021-05-18 | Order-Made Medical Research Inc. | Antibody inhibiting binding of VEGF to NRP1 |
KR102293755B1 (ko) | 2016-01-06 | 2021-08-24 | 오더-메이드 메디컬 리서치 인코포레이티드 | 고친화성 항vegf 항체 |
CN107537036A (zh) * | 2016-06-27 | 2018-01-05 | 江苏泰康生物医药有限公司 | 一种抗人血管内皮生长因子单克隆抗体的药物制剂及其应用 |
CN110003328B (zh) * | 2018-01-05 | 2022-04-19 | 百奥泰生物制药股份有限公司 | 一种长效低毒的重组抗vegf人源化单克隆抗体及其生产方法 |
CN112203679A (zh) | 2018-03-02 | 2021-01-08 | 科达制药股份有限公司 | Il-6抗体及其融合构建体和缀合物 |
JP7352007B2 (ja) * | 2019-07-19 | 2023-09-27 | 神州細胞工程有限公司 | ヒト化抗vegfモノクローナル抗体 |
CN114786731A (zh) | 2019-10-10 | 2022-07-22 | 科达制药股份有限公司 | 治疗眼部病症的方法 |
BR112023016095A2 (pt) * | 2021-02-10 | 2023-11-14 | Jiangxi Jemincare Group Co Ltd | Anticorpo anti-vegf e uso do mesmo |
CN115850470B (zh) * | 2022-12-12 | 2023-07-07 | 三门峡市眼科医院 | Vegf抗体及其应用 |
CN116003619B (zh) * | 2022-12-12 | 2023-08-04 | 三门峡市眼科医院 | 人源化抗Ang-2和VEGF双功能抗体及其医药用途 |
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CN101918442A (zh) * | 2007-11-30 | 2010-12-15 | 基因技术公司 | 抗vegf抗体 |
CN102065888A (zh) * | 2008-03-26 | 2011-05-18 | 宜康公司 | 抗-vegf抗体 |
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Effective date of registration: 20180820 Address after: California Co-patentee after: JIANGSU SIMCERE PHARMACEUTICAL Co.,Ltd. Patentee after: Apexigen, Inc. Address before: 210042 Xuanwu Road, Nanjing, Nanjing, Jiangsu, -18 Co-patentee before: EPITOMICS, Inc. Patentee before: JIANGSU SIMCERE PHARMACEUTICAL Co.,Ltd. |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20240430 Address after: 321 Harrison Avenue, 11th Floor, Suite 1, Boston, Massachusetts, USA Patentee after: Apexigen, Inc. Country or region after: U.S.A. Patentee after: Jiangsu Xiansheng Biopharmaceutical Co.,Ltd. Country or region after: China Address before: California, USA Patentee before: Apexigen, Inc. Country or region before: U.S.A. Patentee before: JIANGSU SIMCERE PHARMACEUTICAL Co.,Ltd. Country or region before: China |