CN102429096A - Feed additive and application of feed additive for alleviating diarrhea of piglet - Google Patents
Feed additive and application of feed additive for alleviating diarrhea of piglet Download PDFInfo
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- CN102429096A CN102429096A CN2011103549619A CN201110354961A CN102429096A CN 102429096 A CN102429096 A CN 102429096A CN 2011103549619 A CN2011103549619 A CN 2011103549619A CN 201110354961 A CN201110354961 A CN 201110354961A CN 102429096 A CN102429096 A CN 102429096A
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Abstract
The invention provides a feed additive and an application of the feed additive for alleviating diarrhea of piglet. The feed additive comprises the following components: no less than 2*10<9>/g of bacillus licheniformis, no less than 4*10<9>/g of bacillus subtilis, no more than 5*10<7>/g of butyric acid bacteria, small peptide with the content of being no less than 300mg/g and no less than 500mg/g of carrier. The feed additive provided by the invention can inhibit growth and breeding of harmful bacteria such as enteropathogenic escherichia coil, salmonella and the like and can effectively reduce occurring rate of yellow and white sour and other intestinal tract bacterial diarrhea of piglet; and butyric acid, metabolite of butyric acid bacteria, can promote regeneration and repairing of intestinal tract epithelial cells and improve absorbing capacity of intestinal tract. The feed additive provided by the invention has the advantages of safety, high efficiency, specificity, no residue, no side effect and the like.
Description
Technical field
The invention belongs to the livestock feed technical field, relate to feed addictive, be specifically related to a kind of microbial forage additive and the application in alleviating grice diarrhoea thereof.
Background technology
It is the foundation phase of Swine Production that the breast piglet is cultivated, and also is the stage of most critical in the management process of raising pigs.Because the piglet physiological development is unsound, the ability of resisting extraneous poor environment is relatively poor, has brought great difficulty for feeding and management, disease prevention and cure.The breast piglet is from the birth beginning, and outer derived bacterium just begins to invade animal intestinal, and forms metastable flora environment gradually.Birth back 3h, aerobic bacteria and facultative anaerobe just become dominant microflora (reach total bacterium measure 80%).Afterwards, anaerobic bacteria substitutes aerobic bacteria gradually, and kind increases gradually, during suckling, is main with Bifidobacterium, clostridium and bacterioid.From be born to growing up, the influence that changed by environment and daily ration, the gut flora of pig is in the continuous variation, wherein, is that gut flora changes the maximum stage before and after the wean.The significant change that gut flora takes place before and after the wean is following: 1, total number of bacteria descends; 2, anaerobic bacteria quantity descends to some extent, and the quantity of Bacillus acidi lactici can descend 100 times; 3, aerobic bacteria quantity rises, and Escherichia coli quantity rises 50 times; 4, the ratio of the G-bacterium in the large intestine obviously increases, and variation intestinal microflora causes piglet to be suffered from diarrhoea easily.The pig farm that grice diarrhoea takes place reaches more than 80%, grice diarrhoea incidence 20%-50%, and diarrhoea piglet Abwehrkraft des Koepers descends, and the secondary disease incidence increases; Weight gain of piglets slows down, and the price of deed reduces; Even growth inhibited, become cad pig.Therefore, grice diarrhoea is controlled to such an extent that fine or not becoming gradually weighed piglet and cultivate one of important indicator of success or not.
Cause the main cause of grice diarrhoea that flora imbalance, digestive ferment deficiency are arranged.Generally usually treat or prevent grice diarrhoea, but add the damage that antibiotic is prone to cause enteron aisle, liver, kidney by adding antibiosis.In pig starter feed, add probiotics at present and also can improve the grice diarrhoea phenomenon to a certain extent, probiotics is meant the beneficial microbe and the metabolite thereof that can promote microecological balance in the animal body.Because the diarrhoea that reasons such as microbial forage additive digestive ferment deficiency, flora imbalance cause all has better curative effect; But the direction of improving because of various bacterium in the probiotics is also inconsistent, so monistic probiotics can not effectively be prevented and treated multiple grice diarrhoea.
Summary of the invention
High but do not control the present situation of the effective ways of grice diarrhoea to grice diarrhoea incidence in the prior art; The invention provides a kind of feed addictive and the application in reducing grice diarrhoea thereof; Feed addictive according to the invention can suppress the growth and breeding of harmful bacterium such as enteropathogenic E, salmonella, effectively reduces the incidence of newborn piglet Huang, dysentery characterized by white mucous stool and other enteric bacteria property diarrhoea.
For realizing the foregoing invention purpose, the present invention adopts following technical proposals to be achieved:
A kind of feed addictive, said feed addictive comprises following component, by mass percentage: bacillus licheniformis bacterium amount is not less than 2 * 10
9Individual/g; Bacillus subtilis bacterium amount is not less than 4 * 10
9Individual/g; Miyarisan bacterium amount is not higher than 5 * 10
7Individual/g; The content of little peptide is not less than 300mg/g, and vector contg is not less than 500mg/g.
Further improvement to technical scheme: said bacillus licheniformis bacterium amount is 2 * 10
9Individual/g; Said bacillus subtilis bacterium amount is 4 * 10
9Individual/g; Said Miyarisan bacterium amount is 5 * 10
7Individual/g; Said little peptide content is 300mg/g; Said vector contg is 500mg/g.
Further improvement to technical scheme: described carrier is a maize peel, and 30 order oversizes are 0.
The present invention also provides the application of feed addictive in alleviating grice diarrhoea.
Further improvement to technical scheme: the addition of said feed addictive is 1 ‰ of a perfect compound feed gross weight-2 ‰, directly it is added in the piglet diet perfect compound feed and feeds.
Further improvement to technical scheme: said feed addictive is fed with premix or concentrate feed form and is given piglet.
Compared with prior art; Advantage of the present invention and good effect are: the nosogenesis that the present invention is directed to piglet trophism and bacterial diarrhea; Quick reparation perfect and intestinal mucosa with function of intestinal canal is a target, and the characteristics according to newborn intestine of young pigs development characteristics and feed composition provide a kind of feed addictive; It selects the multiple Bacillus strain that germination rate is high, the field planting ability is strong for use; Evenly distribute in enteron aisle with Miyarisan etc., can suppress the growth and breeding of harmful bacterium such as enteropathogenic E, salmonella, reduce effectively that newborn piglet is yellow, the incidence of dysentery characterized by white mucous stool and other enteric bacteria property diarrhoea.
After the advantages specific embodiment of the present invention, other characteristics of the present invention and advantage will become clearer.
Description of drawings
Fig. 1 is the sem photograph of the piglet intestinal villus behind antibiotic therapy among the present invention.
Fig. 2 is the sem photograph of the piglet intestinal villus after the feed addictive treatment of the present invention.
The specific embodiment
Below in conjunction with the accompanying drawing and the specific embodiment technical scheme of the present invention is done further detailed explanation.
Embodiment 1
Feed addictive according to the invention is a composite type microecology preparation, and it comprises following component, and by mass percentage: bacillus licheniformis content is not less than 2 * 10
9Individual/gram; The bacillus subtilis bacterial content is not less than 4 * 10
9Individual/gram; Miyarisan content is not higher than 5 * 10
7Individual/gram; The content of little peptide is not less than 300 milligrams/gram, and carrier is not less than 500mg/g.
The concrete component of microbial forage additive described in the present embodiment is: bacillus licheniformis bacterium amount is 2 * 10
9Individual/g; Bacillus subtilis bacterium amount is 4 * 10
9Individual/g; Miyarisan bacterium amount is 5 * 10
7Individual/g; Little peptide content is 300mg/g; Vector contg is 500mg/g.Described carrier is a maize peel, and 30 order oversizes are 0.
The application process of feed addictive according to the invention in alleviating piglet trophism and bacterial diarrhea is: the addition of said feed addictive directly adds these article in the piglet diet perfect compound feed to for according to 1 ‰ of perfect compound feed gross weight-2 ‰; Or be mixed and made into premix with other feed addictive or feedstuff, the concentrate feed form is fed and is given piglet, with prevention with treat its trophism and bacterial diarrhea.
Every nest diarrhoea suckling pig is divided into 2 groups at random, and the I group is injected colistin sulfate parenteral solution 0.5ml every day, and II organizes and uses compound micro-ecological preparation 2ml, every day 1 time every day.Experimental result is as shown in table 1; Probiotics according to the invention has better therapeutic effect for suckling pig diarrhoea; Though to compare difference not remarkable with the antibiotic therapy group; But consider after the injection of antibiotics generation stress, be treated more greatly to be prone to wait repeatedly factor, use the probiotics resultant effect obviously to be superior to the antibiotic therapy group.
The result of treatment that table 1, the present invention suffer from diarrhoea to suckling pig
Embodiment 2, feed addictive are tested the reparation of newborn piglet intestinal villus
Every nest diarrhoea suckling pig is divided into 2 groups at random, and the I group is injected colistin sulfate parenteral solution 0.5ml every day, and II organizes and uses compound micro-ecological preparation 2ml, every day 1 time every day.Experimental result is as depicted in figs. 1 and 2; Can find out by electron scanning figure; It is widely different that piglet yellow-white dysentery employing distinct methods is treated rear intestinal mucous membrane reparation situation; Adopt the intestinal mucosa after compound micro-ecological preparation is treated more smooth, so adopt the reparation of compound micro-ecological preparation treatment rear intestinal mucous membrane obviously to be superior to the antibiotic therapy group than the intestinal mucosa of antibiotic therapy group.
Above embodiment is only in order to explaining technical scheme of the present invention, but not limits it; Although the present invention has been carried out detailed explanation with reference to previous embodiment, for the person of ordinary skill of the art, still can make amendment to the technical scheme that previous embodiment is put down in writing, perhaps part technical characterictic wherein is equal to replacement; And these modifications or replacement do not make the essence of relevant art scheme break away from the spirit and the scope of the present invention's technical scheme required for protection.
Claims (6)
1. feed addictive, it is characterized in that: said feed addictive comprises following component, by mass percentage: bacillus licheniformis bacterium amount is not less than 2 * 10
9Individual/g; Bacillus subtilis bacterium amount is not less than 4 * 10
9Individual/g; Miyarisan bacterium amount is not higher than 5 * 10
7Individual/g; The content of little peptide is not less than 300 mg/g, and vector contg is not less than 500 mg/g.
2. a kind of feed addictive according to claim 1 is characterized in that: said bacillus licheniformis bacterium amount is 2 * 10
9Individual/g; Said bacillus subtilis bacterium amount is 4 * 10
9Individual/g; Said Miyarisan bacterium amount is 5 * 10
7Individual/g; Said little peptide content is 300 mg/g; Said vector contg is 500 mg/g.
3. a kind of feed addictive according to claim 1 and 2 is characterized in that: described carrier is a maize peel, and 30 order oversizes are 0.
4. the application of a kind of feed addictive according to claim 1 and 2 in alleviating grice diarrhoea.
5. the application of a kind of feed addictive according to claim 4 in alleviating grice diarrhoea; It is characterized in that: the addition of said feed addictive is 1 ‰ of a perfect compound feed gross weight-2 ‰, directly it is added in the piglet diet perfect compound feed and feeds.
6. the application of a kind of feed addictive according to claim 4 in alleviating grice diarrhoea is characterized in that: said feed addictive is fed with premix or concentrate feed form and is given piglet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103549619A CN102429096A (en) | 2011-11-10 | 2011-11-10 | Feed additive and application of feed additive for alleviating diarrhea of piglet |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103549619A CN102429096A (en) | 2011-11-10 | 2011-11-10 | Feed additive and application of feed additive for alleviating diarrhea of piglet |
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| CN102429096A true CN102429096A (en) | 2012-05-02 |
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| CN2011103549619A Pending CN102429096A (en) | 2011-11-10 | 2011-11-10 | Feed additive and application of feed additive for alleviating diarrhea of piglet |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107156481A (en) * | 2017-05-22 | 2017-09-15 | 南宁学院 | A kind of feed addictive for preventing and treating grice diarrhoea and preparation method thereof |
| CN107927405A (en) * | 2018-01-05 | 2018-04-20 | 浙江新篁生物技术有限公司 | A kind of son's pig feed additive and its manufacture method |
| CN112352874A (en) * | 2020-11-11 | 2021-02-12 | 贵州省畜牧兽医研究所 | Anti-piglet diarrhea probiotic preparation and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1703968A (en) * | 2004-05-25 | 2005-12-07 | 中国农业大学 | Synbiotic feed addictive of mini-peptide with beneficial microbe and its usage |
-
2011
- 2011-11-10 CN CN2011103549619A patent/CN102429096A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1703968A (en) * | 2004-05-25 | 2005-12-07 | 中国农业大学 | Synbiotic feed addictive of mini-peptide with beneficial microbe and its usage |
Non-Patent Citations (4)
| Title |
|---|
| 华均超等: "微生态制剂对仔猪肠道微生态调控的研究与应用进展", 《中国饲料》, no. 3, 15 February 2011 (2011-02-15) * |
| 吴红照等: "不同好氧特性益生菌在有氧和无氧条件下的增殖", 《饲料研究》, no. 6, 30 June 2011 (2011-06-30) * |
| 姜晓明等: "酪酸菌复合微生态制剂对哺乳仔猪黄白痢治疗效果研究", 《第四届第十次全国学术研讨会暨动物微生态企业发展论坛论文集（下册）》, 31 December 2010 (2010-12-31) * |
| 高媛媛等: "微生态制剂对断奶仔兔肠道微生物菌群与肠道形态结构的影响", 《山地农业生物学报》, vol. 30, no. 2, 30 April 2011 (2011-04-30) * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107156481A (en) * | 2017-05-22 | 2017-09-15 | 南宁学院 | A kind of feed addictive for preventing and treating grice diarrhoea and preparation method thereof |
| CN107927405A (en) * | 2018-01-05 | 2018-04-20 | 浙江新篁生物技术有限公司 | A kind of son's pig feed additive and its manufacture method |
| CN112352874A (en) * | 2020-11-11 | 2021-02-12 | 贵州省畜牧兽医研究所 | Anti-piglet diarrhea probiotic preparation and preparation method thereof |
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Application publication date: 20120502 |