CN102187945B - Additive for balancing gastrointestinal health of animals - Google Patents

Additive for balancing gastrointestinal health of animals Download PDF

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Publication number
CN102187945B
CN102187945B CN2011101823731A CN201110182373A CN102187945B CN 102187945 B CN102187945 B CN 102187945B CN 2011101823731 A CN2011101823731 A CN 2011101823731A CN 201110182373 A CN201110182373 A CN 201110182373A CN 102187945 B CN102187945 B CN 102187945B
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China
Prior art keywords
additive
percent
balancing
tributyrin
glutamine
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Expired - Fee Related
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CN2011101823731A
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Chinese (zh)
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CN102187945A (en
Inventor
陆政
程聪
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SHANGHAI WELL-ADD BIOTECHNOLOGY Co Ltd
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SHANGHAI WELL-ADD BIOTECHNOLOGY Co Ltd
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Abstract

The invention provides an additive for balancing the gastrointestinal health of animals, which is prepared by absorbing 3 to 15 percent of tributyrin, 21.5 to 52.5 percent of lactic acid and 3.5 to 7.5 percent of formic acid with special carrier white black carbon by grade and layer respectively and then combining the mixture with 1 to 10 percent of glutamine. The additive has the effects of controlling diarrhea and accelerating restoration of injured intestinal tract, and starting from a philosophy of balancing the relationship between the gastropore and the intestinal tract, saving resources, reducing environment loads and improving quality of livestock products, a comprehensive gastrointestinal health management scheme is provided.

Description

The additive that a kind of balance animal gastrointestinal tract is healthy
Technical field
The present invention relates to a kind of functional additive, particularly a kind of promotion animal digestion, control is suffered from diarrhoea and is accelerated the growth promotion functional additive that impaired enteron aisle recovers.
Background technology
The main at present digestion that promotes nutriment through acidulant; Acidulant can be through reducing stomach inner pH value; Promote the secretion of hydrochloric acid in gastric juice, and then improve the especially digestion of protein of nutriment, prevent entering enteron aisles such as indigested protein; Become the culture medium that all kinds of pathogen are grown, cause young animal diarrhoea even dead.Though but acidulant can promote the digestion of protein, to the no restitution of intestinal mucosa damage that stress wait factor to cause.
Sodium butyrate and encapsulate sodium butyrate, butyric acid mainly through in enteron aisle, discharging recovery and the growth that butyric acid promotes intestinal mucosa be the intestinal mucosa epithelial cell growth recover utilize the energy fast.But sodium butyrate legibility under one's belt leaves, and butyric acid is absorbed by coat of the stomach, and butyric acid can not effectively arrive impaired enteron aisle and play a role.Can partly solve the phenomenon of dissociating in the stomach though encapsulate sodium butyrate, it is low to encapsulate sodium butyrate active ingredient, costs an arm and a leg, suitable a large amount of the use, thus do not reach the amount that enough promotion mucous membranes recover required butyric acid.
The use of zinc oxide can be good at control diarrhoea in young animal, suppress but growth of animal can appear in the long-term use of zinc oxide, and degradation manifests under the feed intake, and in case stop using very easily recurrence; And use zinc oxide can suppress the absorption of other mineral element for a long time, and environment is caused very big pollution.
Though diarrhoea can be effectively controlled in antibiotic a large amount of use, bacterium very easily produces drug resistance, the long-term autochthonous flora that can destroy enteron aisle that uses, and maximum harm is to have residually in the end product, endangers our human beings'health.
Only all there is the problem to stomach or the single solution of enteron aisle in existing scheme, and employed product exists various deficiencies and side effect, but young animal especially weanling pig in stress process, have the problem aspect stomach and the enteron aisle two.
Summary of the invention
The object of the present invention is to provide the healthy additive of a kind of balance animal gastrointestinal tract; This additive can provide a kind of comprehensive intestines and stomach health management scheme from the relation of balance stomach and enteron aisle and the theory that economizes on resources, alleviates environmental pressure, raising livestock products quality.
Additive of the present invention is by the carrier white carbon; Hierarchical classification time respectively with the tributyrin 3%-15% of following percentage by weight, lactic acid 21.5%-52.5%, formic acid 3.5%-7.5% absorption; Compound with glutamine 1%-10% again, processing can the balance peptic digest and the functional additive that recovers of enteron aisle.
Described additive is processed by following raw materials by weight percent: tributyrin 10%-15%, lactic acid 21.5%-52.5%, formic acid 3.5%-7.5%, glutamic acid 1%-10%.
Described additive is processed by the raw material of following preferred weight percent: tributyrin 10%, lactic acid 38%, formic acid 6.5%, glutamine 2%.
The present invention has guaranteed protein abundant digestion under one's belt from the angle of balance, and the recovery of impaired enteron aisle, is beneficial to the abundant absorption of nutriment.
The present invention has following effect:
(1) hierarchical classification through the carrier white carbon adsorbs with lactic acid, formic acid; Can make this product full and uniform release organic acid in the stomach; Reduce animal gastrointestinal tract pH value; Promote protein-based material digestion, improve feed conversion rate, thereby reduce secondary damage enteron aisle fine hair in damaged condition; Regulate gastral acidity through reducing the pH value in addition, can effectively bring into play bacteriostasis, and the molecule in the organic acid can directly get into the cell membrane performance bactericidal action of bacterium.
(2) tributyrin that is adsorbed on above the carrier white carbon needs the lipase effect to decompose, and does not have lipase in the stomach, so can arrive small intestine through stomach; In small intestine, fully acted on the release butyric acid, effectively avoided the butyric acid absorption of dissociating under one's belt, fast to the intestinal villus makeup energy by lipase; Improve the intestinal villus value-added speed; Accelerate the recovery of impaired enteron aisle fine hair, keep normal intestinal permeability, alleviate the physical stress extent of reaction.
(3) glutamine then is the necessary nutriment of intestinal mucosa cellular metabolism, and the integrality of keeping the intestinal mucosa epithelial structure is played crucial effect, can also promote the synthetic of myocyte's internal protein for body provides essential nitrogenous source in addition.
Therefore through using this invention product can reach the problem of balance stomach and enteron aisle two aspects, reach the problem that comprehensive solution digests and absorbs.So just can reduce the use of antibiotic and zinc oxide, alleviate of pressure and replacement antibiotic the use in feed of high zinc, improve the quality of animal product, reduce harm the mankind to environment.
Ratio described in the present invention unless otherwise indicated, all is weight percentage.
Description of drawings
Fig. 1 is that additive experimental example 1 midgut of the present invention is tieed up precious UAD the piglet production performance influenced result of the test figure.
The specific embodiment
Below through specific embodiment and accompanying drawing technical scheme of the present invention is described further.In these embodiment, unless otherwise indicated, all percentage compositions all by weight.
Embodiment 1:
Carrier white carbon, hierarchical classification time respectively with tributyrin 10%, lactic acid 38%, formic acid 6.5% absorption, compound with glutamine 2% again, processing can the balance peptic digest and the functional additive (the intestines dimension is precious) that recovers of enteron aisle.
Embodiment 2:
Carrier white carbon, hierarchical classification time respectively with tributyrin 3%, lactic acid 21.5%, formic acid 3.5% absorption, compound with glutamine 1% again, processing can the balance peptic digest and the functional additive that recovers of enteron aisle.
Embodiment 3:
Carrier white carbon, hierarchical classification time respectively with tributyrin 15%, lactic acid 52.5%, formic acid 7.5% absorption, compound with glutamine 10% again, processing can the balance peptic digest and the functional additive that recovers of enteron aisle.
Through concrete experimental data, the effect of the functional additive that the present invention is prepared (the intestines dimension is precious) is described further.
Experimental example 1:
The precious influence of intestines dimension to child care pig production performance
In order to verify the precious effect that the stage uses on wean child care pig of intestines dimensions, the spy is arranged in certain plant and chose 300 child care pigs totally in 21 days and compare test, existing result of the test is reported as follows:
1. test objective
Precious through interpolation intestines dimension in the child care material, reduce infection of digestive canal pressure, promote protein digestibility, the absorption of the quick growth of enteron aisle fine hair and then promotion nutriment improves efficiency of feed utilization, improves child care pig economic benefit.
2. experimental design
Select already sterilised preparation to raise the child care house of piglet.The piglet of 28 ages in days wean is changed over to; Wherein one group is made as intestines and ties up precious test group (addition 6kg); Other one group is made as and adds zinc oxide (3kg), sodium butyrate (1.5kg), certain company's acidulant (4kg) group in the child care material; The 3rd group is made as the blank group, and every group all is 100, and average weight is 7.5kg.The raising condition is consistent.
3. materials and methods
3.1 material
Intestines Wei Bao Sino-U.S. cooperation Shanghai ten thousand germinating thing Co., Ltds provide
3.2 method
3.2.1 raise by conventional method for breeding, keep each group to raise term harmonization, carry out environmental sanitation work.
3.2.2 the record feed consumption rate, diarrhea rate, the experiment end is heavy.
4. result of the test
Test was carried out 21 days altogether, only totally 300 of the pigs of participating in the experiment.The result of whole test sees Fig. 1.

Claims (2)

1. the healthy additive of a balance animal gastrointestinal tract; It is characterized in that: this additive is by the carrier white carbon; With following raw materials by weight percent tributyrin 3%-15%, lactic acid 21.5%-52.5%, time absorption of formic acid 3.5%-7.5% hierarchical classification, process with glutamine 1%-10% is compound again.
2. additive according to claim 1 is characterized in that: the percentage by weight of above-mentioned raw materials is following: tributyrin 10%-15%, lactic acid 21.5%-52.5%, formic acid 3.5%-7.5%, glutamine 1%-10%.
3. additive according to claim 1 is characterized in that: the preferred weight percent of above-mentioned raw materials is following: tributyrin 10%, lactic acid 38%, formic acid 6.5%, glutamine 2%.
CN2011101823731A 2011-07-01 2011-07-01 Additive for balancing gastrointestinal health of animals Expired - Fee Related CN102187945B (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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CN102187945B true CN102187945B (en) 2012-08-15

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Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102919581A (en) * 2012-10-30 2013-02-13 浙江科盛饲料股份有限公司 Feed additive, functional feed, and preparation method and application of functional feed
CN103340296B (en) * 2013-07-30 2014-08-13 集美大学 Intestinal health regulator for fugu rubripes and preparation method of regulator
ES2666909T3 (en) * 2013-10-14 2018-05-08 Perstorp Ab Composition that prevents necrotic enteritis in Galloanserae
CN104106734A (en) * 2014-06-27 2014-10-22 浙江大学 Tributyrin solid granular preparation, and preparation method and application thereof
CN104304675B (en) * 2014-10-13 2017-05-10 武汉轻工大学 Antibacterial feed additive and application
CN104323029A (en) * 2014-11-05 2015-02-04 集美大学 Composite type intestinal-health regulating agent for groupers and preparation method thereof
CN107691777A (en) * 2017-09-26 2018-02-16 广州傲农生物科技有限公司 A kind of feed addictive and its application for weanling pig
CN107668348A (en) * 2017-10-12 2018-02-09 广州傲农生物科技有限公司 A kind of compound additive for improving intestine of young pigs health and preparation method and application
AU2019289804A1 (en) * 2018-06-22 2021-01-14 Basf Se Compositions for animals and uses thereof
CN109463352B (en) * 2018-11-29 2020-08-07 深圳农畉农产品有限公司 Method for reducing skatole in live pigs

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CN101283735B (en) * 2007-08-10 2011-11-16 广东海纳川药业股份有限公司 Microcapsule acidifier and its preparation method
CN101692870A (en) * 2009-10-10 2010-04-14 四川省畜科饲料有限公司 Formula and use method of forage addition acidifier
CN101715898B (en) * 2009-11-27 2012-10-03 济南天天香有限公司 Acidating agent for newborn piglet feed and preparation method thereof
CN102008013B (en) * 2010-10-29 2012-09-26 上海美农生物科技股份有限公司 Protective feed acidifier and processing method thereof

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