CN102415979B - Whitening and freckle-removing cream - Google Patents
Whitening and freckle-removing cream Download PDFInfo
- Publication number
- CN102415979B CN102415979B CN 201110437315 CN201110437315A CN102415979B CN 102415979 B CN102415979 B CN 102415979B CN 201110437315 CN201110437315 CN 201110437315 CN 201110437315 A CN201110437315 A CN 201110437315A CN 102415979 B CN102415979 B CN 102415979B
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- whitening
- percent
- cream
- freckle
- chinese medicine
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- 230000002087 whitening effect Effects 0.000 title claims abstract description 25
- 239000006071 cream Substances 0.000 title abstract description 16
- 208000003351 Melanosis Diseases 0.000 title abstract description 11
- 238000002360 preparation method Methods 0.000 claims abstract description 15
- 239000003814 drug Substances 0.000 claims description 16
- 239000007788 liquid Substances 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 238000000605 extraction Methods 0.000 claims description 8
- 238000009835 boiling Methods 0.000 claims description 6
- 239000008367 deionised water Substances 0.000 claims description 6
- 229910021641 deionized water Inorganic materials 0.000 claims description 6
- 241000628997 Flos Species 0.000 claims description 3
- 235000008109 Thuja occidentalis Nutrition 0.000 claims description 3
- 230000008030 elimination Effects 0.000 claims description 3
- 238000003379 elimination reaction Methods 0.000 claims description 3
- 239000012567 medical material Substances 0.000 claims description 3
- 239000003643 water by type Substances 0.000 claims description 3
- 240000003243 Thuja occidentalis Species 0.000 claims 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 abstract description 12
- 230000000694 effects Effects 0.000 abstract description 7
- 235000010215 titanium dioxide Nutrition 0.000 abstract description 7
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract description 4
- 239000000049 pigment Substances 0.000 abstract description 4
- 230000005808 skin problem Effects 0.000 abstract description 3
- 230000015572 biosynthetic process Effects 0.000 abstract description 2
- 230000017531 blood circulation Effects 0.000 abstract description 2
- 230000001737 promoting effect Effects 0.000 abstract description 2
- 230000001105 regulatory effect Effects 0.000 abstract description 2
- 206010067982 Butterfly rash Diseases 0.000 abstract 1
- 235000007516 Chrysanthemum Nutrition 0.000 abstract 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 abstract 1
- 206010014970 Ephelides Diseases 0.000 abstract 1
- 241000736211 Platycladus Species 0.000 abstract 1
- 244000046146 Pueraria lobata Species 0.000 abstract 1
- 235000010575 Pueraria lobata Nutrition 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 241000954737 Thuja sutchuenensis Species 0.000 abstract 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 12
- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 description 10
- 239000000463 material Substances 0.000 description 9
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 8
- 206010008570 Chloasma Diseases 0.000 description 6
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 6
- 239000000203 mixture Substances 0.000 description 6
- -1 polyoxypropylene Polymers 0.000 description 6
- 229920001436 collagen Polymers 0.000 description 5
- 229960000735 docosanol Drugs 0.000 description 5
- 239000004408 titanium dioxide Substances 0.000 description 5
- AMUTYVGRCVFCCD-UHFFFAOYSA-N 5,6-diaminopyridine-3-carboxylic acid Chemical compound NC1=CC(C(O)=O)=CN=C1N AMUTYVGRCVFCCD-UHFFFAOYSA-N 0.000 description 4
- 102000008186 Collagen Human genes 0.000 description 4
- 108010035532 Collagen Proteins 0.000 description 4
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 4
- 229930182478 glucoside Natural products 0.000 description 4
- 150000008131 glucosides Chemical class 0.000 description 4
- YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 description 4
- SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 description 4
- 229920001451 polypropylene glycol Polymers 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 3
- 208000037259 Amyloid Plaque Diseases 0.000 description 3
- 229920001184 polypeptide Polymers 0.000 description 3
- 102000004196 processed proteins & peptides Human genes 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- 241000218636 Thuja Species 0.000 description 2
- 230000002421 anti-septic effect Effects 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 229910052753 mercury Inorganic materials 0.000 description 2
- 238000006386 neutralization reaction Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 210000004927 skin cell Anatomy 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 229910000004 White lead Inorganic materials 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 229940025084 amphetamine Drugs 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000000498 cooling water Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Abstract
The invention discloses whitening and freckle-removing cream and a preparation method thereof. The whitening and freckle-removing Chinese medicinal preparation comprises the following components in percentage by weight: 5 to 55 percent of root of kudzu vine, 15 to 35 percent of platycladus, 5 to 15 percent of rehmannia root, 5 to 45 percent of yam, 15 to 20 percent of thuja sutchuenensis and 5 to 10 percent of chrysanthemum. The cream provided by the invention can inhibit the formation of melanin while exerting a comprehensive regulating whitening and freckle-removing effect by promoting blood circulation, removing stasis, clearing heat and detoxifying the cream can be applied conveniently, and nano titanium white is added at the same time for achieving instant whitening effect. After the cream is used continuously for 28 days, the skin problems aroused by freckles, butterfly rash, age pigment and other chromatosis can be solved.
Description
Technical field
The invention belongs to the cosmetics technical field, be specifically related to a kind of whitening and speckle dispelling Chinese medicine preparation with and preparation method thereof.
Background technology
Whitening and speckle dispelling is the target that women that great majority are liked to be beautiful pursues, and the beauty treatment circle almost is used as unique effective whitening cosmetics to preparation mercurous, hydroquinone.Contain forbidden amphetamine and cross and take effect ten thousand times one week of mercury and mercuric compounds speckle dispelling, toxicity is gathered and is caused countless consumers face cell downright bad, stays the blue patch that can not cure; The amount of limiting the use of of hydroquinone is 0.02%, and the hydroquinone that surpasses the amount of limiting the use of hundreds of times just has positive effect, if but life-time service can be repent forever staying abnormal white piece on the face.Therefore, how to obtain the problem that safe and effective whitening and speckle dispelling material is puzzlement beauty and make-up industry always.
Summary of the invention
The objective of the invention is for the deficiencies in the prior art, a kind of safely and effectively whitening and speckle dispelling Chinese medicine preparation is provided, effectively solve the calm skin problem that causes of the pigments such as chloasma, butterfly spot, senile plaque, it is easy to use, and effect is remarkable.
Another object of the present invention provides the preparation method of this whitening and spot eliminating cream.
The present invention is achieved through the following technical solutions above-mentioned purpose:
A kind of whitening and speckle dispelling Chinese medicine preparation is characterized in that being comprised of the component of following percetage by weight: Radix Puerariae 5-55%, Cacumen Platycladi 15-35%, Rhizoma Phragmitis 5-15%, Rhizoma Dioscoreae 5-45%, arborvitae 15-20%, Flos Chrysanthemi 5-10%.
The preparation method of whitening and speckle dispelling Chinese medicine preparation may further comprise the steps: each Chinese medicine is mixed in proportion, adds water soaking, be heated to boiling and keep constant temperature, leach medicinal liquid; Medicinal residues add water in addition, again are heated to the boiling slow fire and decoct, and leach medicinal liquid, merge twice medicinal liquid after, be condensed into the Chinese medicine extraction concentrated solution.Preferred extraction scheme is that medical material gross weight 100 grams pulverize, and adds deionized water 200 grams and soaks 24 hours, then is heated to boiling and keeps constant temperature 1 hour, leaches medicinal liquid.Medicinal residues add 100 gram deionized waters in addition, and reheat decocts 30 minutes to boiling, the elimination medicinal residues, with filter for twice medicinal liquid merge, be condensed into 100 gram Chinese medicine extraction concentrated solutions.
A kind of whitening and spot eliminating cream is comprised of the component of following percetage by weight:
Chinese medicine extraction concentrated solution 10.0%, polyoxypropylene glucoside 3.0%, glycerol monostearate 1.5%, spermol 5%, glycerol 2.0%, collagen pentapeptide 3.0%, iso-octyl palmitate 4.0%, nanometer titanium dioxide 4.0%, docosanol 5.0%, carbopol 940 0.3%, triethanolamine 0.3%, antiseptic 0.3%, surplus are deionized water.
A kind of preparation method of whitening and spot eliminating cream may further comprise the steps:
(1) under stirring, in water, spread and add carbopol, be stirred to transparently, be heated into the water material, for subsequent use;
(2) polyoxypropylene glucoside, glycerol monostearate, spermol, glycerol, iso-octyl palmitate are mixed and heated to 85 ℃ as the oil phase raw material;
(3) behind the oil phase heating raw materials with water material mix and blend, add the triethanolamine neutralization, add again nanometer titanium dioxide and docosanol mixture, constant temperature is cooled to 50 ℃ after stirring, and adds collagen polypeptide again, stirs, degassed one-tenth auxiliary material liquid under the vacuum is cooled to 45 ℃;
(4) Chinese medicine extraction liquid is added in the auxiliary material liquid of step (3) gained, keep vacuum outgas, continue to be cooled to 40 ℃, discharging.
Compared with prior art, the present invention has following beneficial effect:
1. but the not only formation of check melanin of whitening and spot eliminating cream provided by the present invention has blood circulation promoting and blood stasis dispelling simultaneously, heat-clearing and toxic substances removing, and the metabolic effect of chafe reaches the whitening and speckle dispelling effect of comprehensively regulating.
The present invention select easy to carry, the cream cream type of smearing easily.Can not enter eyes during use, prescription adds the nano grade titanium white lead to reach instantaneous whitening effect, is popular.
3. add special penetrating agent-collagen polypeptide close with the Skin Cell structure, improve the Skin Cell function.
Whitening and spot eliminating cream provided by the present invention was used 28 days continuously, can eliminate the calm skin problem that causes of the pigments such as chloasma, butterfly spot, senile plaque.
The present invention verifies the beneficial effect of the present invention aspect whitening and speckle dispelling by clinical experimental study.
The specific embodiment
Below further specify technical scheme of the present invention by specific embodiment.
Embodiment 1
The preparation of the concentrated liquid of tradition Chinese medicine:
Radix Puerariae 40 g, Cacumen Platycladi 15 g, Rhizoma Phragmitis 10 g, Rhizoma Dioscoreae 10 g, arborvitae 15g, Flos Chrysanthemi 10g.Merge medical material 100 g and pulverize, add deionized water 200 g and soaked 24 hours, then be heated to boiling and kept constant temperature 1 hour, leach medicinal liquid.Medicinal residues add 100 g deionized waters in addition, and reheat decocts 30 minutes to the slow fire that seethes with excitement, the elimination medicinal residues, with filter for twice medicinal liquid merge, be condensed into 100 g Chinese medicine extraction concentrated solutions.
The preparation of whitening and spot eliminating cream:
The ratio of each material is according to following percentage by weight: Chinese medicine extraction concentrated solution 10.0%, polyoxypropylene glucoside 3.0%, glycerol monostearate 1.5%, spermol 5%, glycerol 2.0%, collagen polypeptide 3.0%, iso-octyl palmitate 4.0%, nanometer titanium dioxide 4.0%, docosanol 5.0%, carbopol 940 0.3%, triethanolamine 0.3%, antiseptic 0.3%, surplus are deionized water.
In the water pot, add deionized water, under 400 rpm high-speed stirred, spread and add carbopol 940, and be stirred to transparently, then be warming up to 85 ℃ as the water material, for subsequent use.
Docosanol mixes with nanometer titanium dioxide, is ground to evenly.
Polyoxypropylene glucoside, glycerol monostearate, spermol, glycerol, iso-octyl palmitate, be mixed and heated to 85 ℃ as the oil phase material.
Add then slow suction water mix and blend of oil phase material in vacuum emulsification pot, homogenizing 4 minutes adds the triethanolamine neutralization, then adds nanometer titanium dioxide and docosanol mixture, and constant temperature stirred 30 minutes, opened cooling water.
Liquid is cooled to 50 ℃, adds collagen pentapeptide, stirs, and is evacuated to 10 millimetress of mercury, and is degassed.
45 ℃ of lower the concentrated liquid of tradition Chinese medicine and other components of adding continue cooling and keep vacuum outgas.
Be cooled to 40 ℃, discharging obtains whitening and spot eliminating cream.
Activity experiment:
The object of observation: 20-45 years old ages middle-aged women.Choosing is facial female middle-aged 106 examples of the pigments such as in various degree chloasma, butterfly spot, senile plaque.
Observational technique: cream frost 3 ~ 5 grams that getting embodiment 1 after washing one's face every morning provides are applied on the face spotted position, and repaste once before the sleep evening, and 28 days is a course for the treatment of.
Criterion of therapeutical effect: 1. recovery from illness: chloasma disappears substantially; 2. produce effects: chloasma disappears more than 50%; 3. effective: chloasma disappears more than 10% or the patch color turns light; 4. invalid: unchanged before and after the treatment.
Therapeutic effect such as table 1:
Table 1
| Grouping | The example number | Recovery from illness | Produce effects | Effectively | Invalid | Total effective rate |
| Embodiment 1 whitening and spot eliminating cream | 106 | 89 | 10 | 5 | 2 | 95% |
Claims (1)
1. a whitening and speckle dispelling Chinese medicine preparation is characterized in that being made by the component of following weight: Radix Puerariae 40 g, Cacumen Platycladi 15 g, Rhizoma Phragmitis 10 g, Rhizoma Dioscoreae 10 g, arborvitae 15g, Flos Chrysanthemi 10g; Merge medical material 100 g and pulverize, add deionized water 200 g and soaked 24 hours, then be heated to boiling and kept constant temperature 1 hour, leach medicinal liquid; Medicinal residues add 100 g deionized waters in addition, and reheat decocts 30 minutes to the slow fire that seethes with excitement, the elimination medicinal residues, with filter for twice medicinal liquid merge, be condensed into 100 g Chinese medicine extraction concentrated solutions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110437315 CN102415979B (en) | 2011-12-23 | 2011-12-23 | Whitening and freckle-removing cream |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110437315 CN102415979B (en) | 2011-12-23 | 2011-12-23 | Whitening and freckle-removing cream |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102415979A CN102415979A (en) | 2012-04-18 |
| CN102415979B true CN102415979B (en) | 2013-01-16 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110437315 Expired - Fee Related CN102415979B (en) | 2011-12-23 | 2011-12-23 | Whitening and freckle-removing cream |
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| Country | Link |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9801809B2 (en) * | 2014-05-05 | 2017-10-31 | Access Business Group International Llc | Compositions including a botanical extract and methods of using the same in skin whitening and skin lightening applications |
| CN106491427A (en) * | 2016-11-08 | 2017-03-15 | 广州生美生物科技有限公司 | A kind of Radix Ginseng Rubra compositionss with moment whitening and preparation method thereof and application |
| CN109350579B (en) * | 2018-12-28 | 2022-03-11 | 广州市科能化妆品科研有限公司 | Whitening cosmetic additive, whitening skin-refreshing lotion and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101390818A (en) * | 2007-09-21 | 2009-03-25 | 罗蔚 | Pimple removing scream |
-
2011
- 2011-12-23 CN CN 201110437315 patent/CN102415979B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101390818A (en) * | 2007-09-21 | 2009-03-25 | 罗蔚 | Pimple removing scream |
Non-Patent Citations (4)
| Title |
|---|
| 侧柏叶黄酮雪花膏配方研制及美白效果评价;赵会芝 等;《安徽农业科学》;20101231;第38卷(第19期);全文 * |
| 徐进 等.葛根在化妆品中的应用初探.《中国野生植物资源》.2000,第19卷(第3期),第11-13页. |
| 葛根在化妆品中的应用初探;徐进 等;《中国野生植物资源》;20001231;第19卷(第3期);第12-13页 * |
| 赵会芝 等.侧柏叶黄酮雪花膏配方研制及美白效果评价.《安徽农业科学》.2010,第38卷(第19期),第10262页. |
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| Publication number | Publication date |
|---|---|
| CN102415979A (en) | 2012-04-18 |
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