CN101653409B - Whitening and spot eliminating cream and preparation method thereof - Google Patents
Whitening and spot eliminating cream and preparation method thereof Download PDFInfo
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- CN101653409B CN101653409B CN2009101922744A CN200910192274A CN101653409B CN 101653409 B CN101653409 B CN 101653409B CN 2009101922744 A CN2009101922744 A CN 2009101922744A CN 200910192274 A CN200910192274 A CN 200910192274A CN 101653409 B CN101653409 B CN 101653409B
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Abstract
The invention discloses whitening and spot eliminating cream and a preparation method thereof. The whitening and spot eliminating cream comprises an active ingredient and auxiliary materials, wherein the active ingredient is a extracting solution of traditional Chinese medicine, and the traditional Chinese medicine comprises the following materials in percentage by weight: 5%-55% of conic gymnadenia rhizome, 15%-35% of ginseng flower, 5%-15% of flos albiziae, 5%-15% of honeysuckle, 15%-20% of flos rosae rugosae and 5%-10% of chrysanthemum. The whitening spot eliminating cream can restrain the generation of melanin, also has the functions of activating blood and dissolving stasis, clearing away heat and toxic materials, achieves the comprehensively regulated whitening and spot eliminating effect and is convenient to use; in addition, the whitening spot eliminating cream adds nanoscale titanium pigment to achieve instant whitening effect and can solve skin problems, i.e. chloasmata, butterfly spots, age pigments, and the like which are caused by chromatosis after being continuously used for 28 days.
Description
Technical field
The invention belongs to the cosmetics technical field, be specifically related to a kind of whitening and spot eliminating cream with and preparation method thereof.
Background technology
Along with the progressively improvement of living standard, people also improve constantly the pursuit of U.S., wish that the appearance that changes oneself has the pale colour of skin, and the whitening cosmetics that waits in expectation has more positive pharmacological effect.For a long time, whitening and speckle dispelling is the target that the women pursued that great majority are liked to be beautiful, and the beauty treatment circle almost is used as unique effective whitening cosmetics to preparation mercurous, hydroquinone.Contain forbidden amphetamine and cross and take effect in ten thousand times hydrargyrum and one week of chemical compound speckle dispelling thereof, toxicity is gathered and is caused the face cell necrosis of countless consumers, stays the blue patch that can not cure; The amount of limiting the use of of hydroquinone is 0.02%, and the hydroquinone that surpasses the amount of limiting the use of hundreds of times just has positive effect, but if life-time service can be repent forever staying abnormal white piece on the face.Therefore, how to obtain the problem that safe and effective whitening and speckle dispelling material is a puzzlement beauty and make-up industry always.
At present domestic the most widely-used and to recognize safe whitening and speckle dispelling material altogether be arbutin, vitamin C and kojic acid.These materials are safe, but simultaneously, also have the shortcoming of DeGrain.Arbutin chemical name: hydroquinone-β-D-glycopyranoside, it can slowly release the activity that hydroquinone stops the enzyme-tryrosinase of melanin generation, demonstrate the melanic effect that suppresses, its arbutin can be to the melanocyte toxigenicity as hydroquinone, the whitening and speckle dispelling raw material that belongs to safety, but the effect of arbutin is too slow, it slowly decomposes the active function that discharges part hydroquinone restraint of tyrosinase and almost is not aware of, all do not have significantly sensation even if life-time service contains the whitening and speckle dispelling product of arbutin, so that people have lost confidence gradually to the whitening and speckle dispelling product that adds arbutin; Vitamin C can be treated posteriority pigmentations such as chloasma hepaticum or Lille melanosis, vitamin C and derivant thereof also are considered to safe whitening and speckle dispelling material, but it is difficult for by skin absorbs, aqueous solution is oxidation deterioration very easily, preserve very difficult, though and successors develop sodium L-ascorbate-2-phosphate, Magnesium L-Asacorbic Acid 2-O-Phosphate etc. and have solved ascorbic stability problem but these derivant poorly water-solubles, be difficult for adding, the usefulness of whitening and speckle dispelling obviously descends; The material that the metabolism of the multiple aspergillus mushroom of kojic acid produces, non-stimulated to skin, can not cause the white macula sequela, human body skin melanin is generated has stronger inhibitory action simultaneously.Kojic acid generates human body skin melanin stronger inhibitory action, usually and composite skin whitening and the sunscreen product of being used as of other whitening and speckle dispelling material, but seldom see independent use kojic acid and the report of remarkable speckle dispelling curative effect is arranged, general whitening and speckle dispelling prescription is also relatively more rare.
Chinese medicine is from natural plant amedica, has different activities compositions such as many active ingredient alkaloids, saponin, flavonoid, organic acid, and different Chinese medicine has different efficacies, as clearing heat, releasing toxin, removing swelling, activating blood circulation to dissipate blood stasis, moisten whiten, YIN nourishing dampness etc.Chinese medicine beauty treatment safe, along with improving constantly of people's living standard, very big change has also taken place in the beauty treatment idea, and traditional Chinese medicine beauty treatment more and more is subjected to people's green grass or young crops and hides.The Chinese medicine that is used for beauty treatment and eliminating spot at present mostly is white Chinese medicine, all has the effect of white skin as the Rhizoma Atractylodis Macrocephalae, Semen Ginkgo, Radix Ampelopsis etc., so can carry out the beauty treatment medicine of whitening and speckle dispelling by the external approach.But in fact, skin whitening is just driven away an aspect of skin speckle, speckle dispelling, more will by activating blood circulation to dissipate blood stasis, soft through eliminating stagnation, disperse comprehensively regulating such as induce sweat and realize.Removing this, how to increase time of contact and the absorbance of white liquid effective ingredient on skin, also is an importance that promotes the cosmetics effect.
Summary of the invention
The objective of the invention is at the deficiencies in the prior art, provide a kind of safely and effectively in white QUBAN SHUANG, effectively solve the calm skin problem that causes of pigments such as chloasma, butterfly spot, senile plaque, it is easy to use, effect is remarkable.
Another object of the present invention provides the preparation method of this whitening and spot eliminating cream.
The present invention is achieved through the following technical solutions above-mentioned purpose:
A kind of whitening and spot eliminating cream, comprise active component and adjuvant, active component is the Chinese medicine extraction concentrated solution, and Chinese medicine is made up of the component of following percetage by weight: Rhizoma Gymnadeniae 5-55%, Flos Ginseng 15-35%, Flos Albiziae 5-15%, Flos Lonicerae 5-15%, Flos Rosae Rugosae 15-20%, Flos Chrysanthemi 5-10%.
Preferred mass ratio is Rhizoma Gymnadeniae 40%, Flos Ginseng 15%, Flos Albiziae 10%, Flos Lonicerae 10%, Flos Rosae Rugosae 15%, Flos Chrysanthemi 10%.
The Chinese medicine extraction concentrated solution is to obtain through following steps: each Chinese medicine is mixed in proportion, adds the water logging bubble, be heated to boiling and keep constant temperature, leach medicinal liquid; Medicinal residues add water in addition, are heated to the boiling slow fire once more and decoct, and leach medicinal liquid, merge twice medicinal liquid after, be condensed into the Chinese medicine extraction concentrated solution.Preferred extraction scheme is that medical material gross weight 100 grams pulverize, and adds deionized water 200 grams and soaks 24 hours, is heated to boiling then and keeps constant temperature 1 hour, leaches medicinal liquid.Medicinal residues add 100 gram deionized waters in addition, and reheat decocts 30 minutes to boiling, the elimination medicinal residues, with filter for twice medicinal liquid merge, be condensed into 100 gram Chinese medicine extraction concentrated solutions.
The mass percent preferred version of Chinese medicine extraction concentrated solution and adjuvant is: Chinese medicine extraction concentrated solution 10.0%, polyoxypropylene glucoside 3.0%, glycerol monostearate 1.5%, spermol 5%, wool oil 2.0%, collagen polypeptide 3.0%, iso-octyl palmitate 4.0%, nanometer titanium dioxide 4.0%, 1,3 butylene glycol 5.0%, carbopol 940 0.3%, triethanolamine 0.3%, antiseptic 0.3%, surplus are deionized water.
Described collagen polypeptide is the mixture of collagen pentapeptide and collagen six peptide, and the content of collagen six peptide accounts for 85%.
A kind of preparation method of whitening and spot eliminating cream may further comprise the steps:
(1) under stirring, in water, spread and add carbopol, be stirred to transparently, be heated into the water material, standby; (2) polyoxypropylene glucoside, glycerol monostearate, spermol, wool oil, iso-octyl palmitate are mixed and heated to 85 ℃ as the oil phase raw material;
(3) stirring is mixed with the water material in oil phase raw material heating back, adds the triethanolamine neutralization, adds nanometer titanium dioxide and 1 again, 3-mixture of butanediols, constant temperature stir postcooling to 50 ℃, add collagen polypeptide again, stir, outgas into auxiliary material liquid under the vacuum, be cooled to 45 ℃;
(4) Chinese medicine extraction liquid is added in the auxiliary material liquid of step (3) gained, keep vacuum outgas, continue to be cooled to 40 ℃, discharging.
The described stirring rotating speed of step (3) is more than the 400rpm.
Step (3) or the described vacuum of step (4) are the 10mm mercury column
Compared with prior art, the present invention has following beneficial effect:
1. whitening and spot eliminating cream provided by the present invention not only can suppress melanic formation, and blood circulation promoting and blood stasis dispelling is arranged simultaneously, heat-clearing and toxic substances removing, and the metabolic effect of chafe reaches the whitening and speckle dispelling effect of comprehensively regulating.
The present invention select easy to carry, the cream cream type of smearing easily.Can not enter eyes during use, prescription adds the nano grade titanium white lead to reach instantaneous whitening effect, is popular.
3. add special penetrating agent-collagen polypeptide close, improve the Skin Cell function with the Skin Cell structure.
Whitening and spot eliminating cream provided by the present invention was used 28 days continuously, can eliminate the calm skin problem that causes of pigments such as chloasma, butterfly spot, senile plaque.
The present invention verifies the beneficial effect of the present invention aspect whitening and speckle dispelling by clinical experimental study.
The specific embodiment
Below further specify technical scheme of the present invention by specific embodiment.
Embodiment 1
The preparation of Chinese medicine concentrated solution:
Rhizoma Gymnadeniae 40g, Flos Ginseng 15g, Acacia farnesiana Willd. 10g, Flos Lonicerae 10g, Flos Rosae Rugosae 15g, Flos Chrysanthemi 10g.Merge medical material 100g and pulverize, add deionized water 200g and soaked 24 hours, be heated to boiling then and kept constant temperature 1 hour, leach medicinal liquid.Medicinal residues add the 100g deionized water in addition, and reheat decocts 30 minutes to the slow fire that seethes with excitement, the elimination medicinal residues, with filter for twice medicinal liquid merge, be condensed into 100g Chinese medicine extraction concentrated solution.
The preparation of whitening and spot eliminating cream:
The ratio of each material is according to following percentage by weight: Chinese medicine extraction concentrated solution 10.0%, polyoxypropylene glucoside 3.0%, glycerol monostearate 1.5%, spermol 5%, wool oil 2.0%, collagen polypeptide 3.0%, iso-octyl palmitate 4.0%, nanometer titanium dioxide 4.0%, 1,3 butylene glycol 5.0%, carbopol 9400.3%, triethanolamine 0.3%, antiseptic 0.3%, surplus are deionized water.
In the water pot, add deionized water, under the 400rpm high-speed stirred, spread and add carbopol 940, and be stirred to transparently, be warming up to 85 ℃ then as the water material, standby.
1,3 butylene glycol mixes with nanometer titanium dioxide, is ground to evenly.
Polyoxypropylene glucoside, glycerol monostearate, spermol, wool oil, iso-octyl palmitate, be mixed and heated to 85 ℃ as the oil phase material.
Add the slowly suction water mixing stirring then of oil phase material in the vacuum emulsification pot, homogenizing 4 minutes adds the triethanolamine neutralization, adds nanometer titanium dioxide and 1,3 butylene glycol mixture then, and constant temperature stirred 30 minutes, opened cooling water.
Liquid is cooled to 50 ℃, adds collagen pentapeptide and collagen six peptide, stirs, and is evacuated to 10 millimetress of mercury, the degassing.
45 ℃ add Chinese medicine concentrated solution and other component down, continue cooling and keep vacuum outgas.
Be cooled to 40 ℃, discharging obtains whitening and spot eliminating cream.
Activity experiment:
The object of observation: age 20-45 year middle-aged women.Choosing is facial middle aged women 106 examples of pigments such as in various degree chloasma, butterfly spot, senile plaque.
Observational technique: cream frost 3～5 grams that getting embodiment 1 after washing one's face every morning is provided are applied to spotted on the face position, sleep preceding repaste evening once, and 28 days is a course of treatment.
Criterion of therapeutical effect: 1. recovery from illness: chloasma disappears substantially; 2. produce effects: chloasma disappears more than 50%; 3. effective: chloasma disappears more than 10% or the patch color changes light; 4. invalid: no change before and after the treatment.
Therapeutic effect such as table 1:
Table 1
| Grouping | The example number | Recovery from illness | Produce effects | Effectively | Invalid | Total effective rate |
| Embodiment 1 Chinese medicine facial film | 106 | 89 | 10 | 5 | 2 | 95％ |
Claims (5)
1. whitening and spot eliminating cream, it is characterized in that comprising active component and adjuvant, active component is the Chinese medicine extraction concentrated solution, and Chinese medicine is made up of the component of following percetage by weight: Rhizoma Gymnadeniae 5-55%, Flos Ginseng 15-35%, Flos Albiziae 5-15%, Flos Lonicerae 5-15%, Flos Rosae Rugosae 15-20%, Flos Chrysanthemi 5-10%; Described Chinese medicine extraction concentrated solution is to obtain through following steps: each Chinese medicine is mixed in proportion, adds the water logging bubble, be heated to boiling and keep constant temperature, leach medicinal liquid; Medicinal residues add water in addition, are heated to the boiling slow fire once more and decoct, and leach medicinal liquid, merge twice medicinal liquid after, be condensed into the Chinese medicine extraction concentrated solution.
2. whitening and spot eliminating cream as claimed in claim 1 is characterized in that being made up of the component of following percetage by weight:
Chinese medicine extraction concentrated solution 10.0%, polyoxypropylene glucoside 3.0%, glycerol monostearate 1.5%, spermol 5%, wool oil 2.0%, collagen polypeptide 3.0%, iso-octyl palmitate 4.0%, nanometer titanium dioxide 4.0%, 1,3 butylene glycol 5.0%, carbopol 940 0.3%, triethanolamine 0.3%, antiseptic 0.3%, surplus are deionized water.
3. whitening and spot eliminating cream as claimed in claim 2 is characterized in that described collagen polypeptide is the mixture of collagen pentapeptide and collagen six peptide, and wherein the mass content of collagen six peptide accounts for 85%.
4. the preparation method of a whitening and spot eliminating cream is characterized in that may further comprise the steps:
(1) under stirring, in water, spread and add carbopol, be stirred to transparently, be heated into the water material, standby;
(2) polyoxypropylene glucoside, glycerol monostearate, spermol, wool oil, iso-octyl palmitate are mixed and heated to 85 ℃ as the oil phase material;
(3) stirring is mixed with the water material in oil phase material heating back, adds the triethanolamine neutralization, adds nanometer titanium dioxide and 1 again, 3-mixture of butanediols, constant temperature stir postcooling to 50 ℃, add collagen polypeptide again, stir, outgas into auxiliary material liquid under the vacuum, be cooled to 45 ℃;
(4) Chinese medicine extraction liquid is added in the auxiliary material liquid of step (3) gained, keep vacuum outgas, continue to be cooled to 40 ℃, discharging; Described Chinese medicine extract is the Chinese medicine mixing with following percetage by weight: Rhizoma Gymnadeniae 5-55%, Flos Ginseng 15-35%, Flos Albiziae 5-15%, Flos Lonicerae 5-15%, Flos Rosae Rugosae 15-20%, Flos Chrysanthemi 5-10%, mix the back and add the water logging bubble, be heated to boiling and keep constant temperature, leach medicinal liquid; Medicinal residues add water in addition, are heated to the boiling slow fire once more and decoct, and leach medicinal liquid, merge twice medicinal liquid after, be condensed into the Chinese medicine extraction concentrated solution.
5. the preparation method of whitening and spot eliminating cream as claimed in claim 4 is characterized in that step (3) or the described vacuum of step (4) are the 10mm mercury column.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2009101922744A CN101653409B (en) | 2009-09-11 | 2009-09-11 | Whitening and spot eliminating cream and preparation method thereof |
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| CN2009101922744A CN101653409B (en) | 2009-09-11 | 2009-09-11 | Whitening and spot eliminating cream and preparation method thereof |
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Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103263364B (en) * | 2013-02-18 | 2015-08-12 | 黄荣波 | The preparation method of the skin-lightening cosmetic containing Radix Bupleuri extract |
| CN103263363B (en) * | 2013-02-18 | 2015-08-12 | 黄荣波 | The preparation method of the skin-lightening cosmetic containing Fructus Corni extract |
| CN103251527B (en) * | 2013-02-18 | 2014-08-06 | 上海道济生物科技有限公司 | Cassiabarktree twig extract-containing whitening cosmetic preparation method |
| CN103431387B (en) * | 2013-08-24 | 2015-04-01 | 湖南绿洲植物资源开发有限公司 | Whitening and freckle-removing traditional Chinese medicine composition and preparation process thereof |
| CN104288054A (en) * | 2014-10-25 | 2015-01-21 | 广州丹奇日用化工厂有限公司 | Chinese herbal medicine composition for removing freckles as well as preparation method and application of Chinese herbal medicine composition |
| CN109288772A (en) * | 2018-11-20 | 2019-02-01 | 张欢 | A kind of whitening and spot eliminating cream and preparation method thereof |
| CN113262180A (en) * | 2021-04-27 | 2021-08-17 | 杭州固拓生物科技有限公司 | Anti-wrinkle skin care cosmetic composition containing polypeptide and preparation method thereof |
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