CN110464752A - A kind of Chinese medicine composition that dispelling body odour and its ointment and preparation method - Google Patents

A kind of Chinese medicine composition that dispelling body odour and its ointment and preparation method Download PDF

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CN110464752A
CN110464752A CN201910928194.4A CN201910928194A CN110464752A CN 110464752 A CN110464752 A CN 110464752A CN 201910928194 A CN201910928194 A CN 201910928194A CN 110464752 A CN110464752 A CN 110464752A
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body odour
ointment
borneol
root
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赵振伟
李君佩
卞国良
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Hunan Zhidakang Biotechnology Co Ltd
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Hunan Zhidakang Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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Abstract

The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition for dispelling body odour and its ointment and preparation method.The Chinese medicine composition that the present invention dispels body odour includes that following parts by weight meter prepares raw material: 5~15 parts of cloves, 5~15 parts of the root of Dahurain angelica, 5~15 parts of alum and 1~5 part of borneol.The traditional chinese medicine composition of the invention is rapid-action, and effect is lasting, can reduce medicine frequency, improves patients ' life quality, has good market prospects.

Description

A kind of Chinese medicine composition that dispelling body odour and its ointment and preparation method
Background technique
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition for dispelling body odour and its ointment and preparation Method.
Technical field
Underarm odor Chinese medicine is referred to as body odour, is a kind of common disease, the definite pathogenesis of underarm odor is still not clear, but has more Experiments have shown that underarm odor is related with the pathocrinia of apocrine sweat gland, and destroy and to dispel apocrine gland in treatment underarm odor effect true It cuts or even whether degree and osmidrosis treatment that apocrine sweat gland is destroyed and dispels is thoroughly directly related, thus modern medicine is referred to as Apocrine sweat gland hircus disease.Foul smell taste occurs in apocrine sweat gland Germ distribution, i.e. armpit, mammary areola, omphalos, private parts and anus etc..Women Related with heredity more than male, sweat gland is in yellow, green, red or black.Sweat gland is decomposed through skin surface bacteria, is generated Unsaturated fatty acid just comes into play to puberty apocrine sweat gland, and old age degenerates, therefore underarm odor is mainly manifested in person between twenty and fifty.Body odour institute The special bad smell of bring, serious person influence the social activity of patient, cause serious psychological burden, or even influence daily life And work.
Body odour treatment has operation and No operation two major classes method, and operative treatment is currently the only possible radical cure method, but It is that there are certain risks for operative treatment, and with certain pain, so the treatment of body odour is based on externally applied drug at present, such as office Portion is using formalin, bromogeramine, neomycin, gentamicin and aluminium, zinc salt etc. to inhibit axillary bacteria to grow;External application antioxygen For agent such as vitamin E to inhibit the formation etc. of fatty acid, above-mentioned external application western medicine has certain curative effect, but 1~2 day after being discontinued Stink generation is had again, so need to be easy to produce medication dependence through common medicine.Chinese medicine has natural medical value, acts on target Point is more, and toxic side effect is low, is the hot spot researched and developed at present applied to body odour is dispelled.
Such as patent document CN106215160A discloses a kind of externally applied liniment for treating body odour, preparing raw material includes: Flos caryophylli, the root of Dahurain angelica, Chinese walnut oil, Sucus Hoveniae, ginger juice, the toast seed of jog's tears, Cortex Phellodendri, purslane, the flower bud of lily magnolia, radix rehmanniae recen, the root bark of Chinese wolf-berry, Mongolian oak Reality, longan seed, Rhizoma Gastrodiae, alum, Chinese prickly ash, Dicliptera chinensis, Buddhist temple dish, sieve cymbopogon distans, weak son, honeycomb and borneol.The externally applied liniment energy It is enough safely and effectively to dispel body odour, but it prepares up to 22 kinds of raw material, and formula is complicated, and preparation cost is high, is unfavorable for promoting and applying.
Therefore, it is necessary to develop, a kind of formula is simple, but effectively dispels the Chinese medicine composition and corresponding ointment of body odour.
Summary of the invention
In order to solve the problems, such as existing body odour product of dispelling (as being formulated complicated, preparation cost height, times for spraying It is more, easy to recur etc.), present invention firstly provides a kind of Chinese medicine compositions for dispelling body odour, and the formula of the composition is simple, raw material It is easy to get, each component collaboration can effectively dispel body odour, reduce medicine frequency.
The present invention dispels the Chinese medicine composition of body odour, prepares raw material including following parts by weight meter: 5~15 parts of cloves, white 5~15 parts of the root of Dahurian angelica, 5~15 parts of alum and 1~5 part of borneol.
Preferably, the Chinese medicine composition for dispelling body odour includes that following parts by weight meter prepares raw material: cloves 10~15 Part, 8~12 parts of the root of Dahurain angelica, 8~12 parts of alum and 1~3 part of borneol.
It is highly preferred that the Chinese medicine composition for dispelling body odour includes that following parts by weight meter prepares raw material: 12 parts of cloves, 10 parts of the root of Dahurain angelica, 10 parts of alum and 2 parts of borneol.
It is highly preferred that the Chinese medicine composition for dispelling body odour is external preparation.
The source of each Chinese medicine of the present invention is as follows: cloves is the dry flower of plant clove of myrtaceae, and the root of Dahurain angelica is umbrella shape The dry root of section's plant root of Dahurain angelica or Radix angelicae dahuricae, alum are that the processed refinement of Sulfates mineral alunite is made, and borneol is composite family The crystallization of extract in Blumea balsamifera platymiscium strong wind folium artemisiae argyi, or the processed goods for Spore density Borneolum Syntheticum resin.
The main chemical compositions of cloves are volatile oil, and eugenol is the important composition ingredient of volatile oil, is cloves performance The material base of various pharmacological actions, therefore, the present invention effectively extract the volatile oil component in cloves, together using ethyl alcohol as solvent When, the present invention uses ethyl alcohol for the main active cumarin and volatile oil in the solvent extraction root of Dahurain angelica, with Flos Caryophylli extract and Angelica Dahurica extract compounding, plays antibacterial action, on the one hand to inhibit the growth of bacterium at the apocrine sweat glands such as armpit;On the other hand it plays Antioxidation, to inhibit the formation of fatty acid;In another aspect, having been generated with its special aromatic odor with covering and removing Stink.Alum and borneol are used as medicine with powder, and alum can further enhance antibacterial and deodorizing effect, and borneol refrigerant antiperspirant and can mention Aromatic odor is risen, enhances deodorizing effect again, to achieve the purpose that effectively to dispel body odour.Therefore the present invention dispels in body odour Drug composition it is rapid-action, and effect is lasting, can reduce medicine frequency, improves patients ' life quality.
In order to allow the traditional chinese medicine composition of the invention preferably to play its effect, the present invention provides a kind of medicines for dispelling body odour Cream comprising following parts by weight meter prepares raw material: 20~30 parts of the Chinese medicine composition for dispelling body odour of the present invention, matrix 70 ~80 parts.
Preferably, the matrix is by vaseline and lanolin by weight 1:(0.2~0.4) it forms.
Correspondingly, the present invention also provides the preparation methods of the above-mentioned ointment for dispelling body odour, specifically includes the following steps:
S1, the cloves for taking formula ratio, are added ethanol solution, and 1.5~2h of refluxing extraction at 55~60 DEG C is filtered, 60 DEG C Under be concentrated into the 1/4 of original volume, be made cloves extracting solution;
S2, the root of Dahurain angelica for taking formula ratio, crushed 40 meshes, and ethanol solution is added, at 55~60 DEG C refluxing extraction 2~ 3h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and root of Dahurain angelica extracting solution is made;
S3, the alum and borneol for taking formula ratio grind alum powder and borneol powder is made respectively;
S4, it takes cloves extracting solution and root of Dahurain angelica extracting solution to mix, is poured slowly into borneol powder, is stirred continuously complete to borneol powder Material, is then poured slowly into alum powder, is stirred until homogeneous by dissolution, and medicinal mixture is made;
S5, it takes the vaseline of formula ratio and lanolin to be mixed and heated to 55~60 DEG C of meltings, pours into medicinal mixture, It is stirred continuously to room temperature, bottled after mixing, the obtained ointment for dispelling body odour.
Further, in the step S1, the solid-to-liquid ratio of cloves and ethanol solution is 1g:(8~13) mL, the ethyl alcohol is molten The volume fraction of liquid is 75~85%.
Further, in the step S2, the solid-to-liquid ratio of the root of Dahurain angelica and ethanol solution is 1g:(6~10) mL, the ethyl alcohol is molten The volume fraction of liquid is 70~80%.
Further, the mesh number of the alum powder is 400 mesh, and the mesh number of the borneol powder is 100 mesh.
The present invention dispels the action component of the Chinese medicine composition of body odour based on volatile oil, and ointment is conventionally made After the problem of being easy to appear water-oil separation, be unfavorable for storing and using for a long time.For this purpose, inventor is special for formula of the invention Point selects vaseline and lanolin to be compounded by a certain percentage as matrix, recycles and contain in cloves extracting solution and root of Dahurain angelica extracting solution Some ethyl alcohol dissolves borneol as solvent, is subsequently added into alum powder, on the one hand a small amount of moisture therein can be absorbed in alum powder And gel is formed, the gel on the other hand formed using it and the adsorbable volatile oil of fine powder with large specific surface area are improved The stability of volatile oil and the loss of volatile oil during the preparation process is reduced, while carrying borneol component and being coated with and waving The alum powder of hair oil can be better dispersed in oil phase substrate, so that the uniform, stable of lotion be effectively ensured, it is ensured that medicine The stabilization of effect and lasting performance.
Therefore, compared with prior art, present invention has an advantage that
(1) formula of the Chinese medicine composition for dispelling body odour and its ointment of the invention is simple, and raw material is easy to get, and preparation cost is low, It is cooperateed with using each component, can effectively dispel body odour, be embodied in rapid-action, effect is lasting, can reduce medicine frequency, improves and suffers from Person's quality of life.
(2) present invention dispel the ointment of body odour preparation method is simple, process stabilizing is, it can be achieved that industrialized production, and make The ointment obtained is uniform, stablizes, and ensure that the stabilization and lasting performance of drug effect.
Specific embodiment
Below by specific embodiment, the present invention is described in further detail.
Embodiment 1, the present invention dispel the Chinese medicine composition, ointment and preparation method of body odour:
Chinese medicine preparation: cloves 1.0kg, root of Dahurain angelica 0.8kg, alum 0.8kg and borneol 0.1kg.
Medical ointment prescription: medicinal mixture 200g, matrix 800g, the matrix is by vaseline and lanolin by weight 1: 0.2 composition.
Ointment preparation method:
Ethanol solution 8L, the refluxing extraction 2h at 60 DEG C that volume fraction is 75% is added in S1, the cloves for taking formula ratio, It filters, is concentrated into the 1/4 of original volume at 60 DEG C, cloves extracting solution is made;
S2, the root of Dahurain angelica for taking formula ratio crushed 40 meshes, the ethanol solution 6L that volume fraction is 70% be added, at 60 DEG C Lower refluxing extraction 2h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and root of Dahurain angelica extracting solution is made;
S3, the alum and borneol for taking formula ratio grind 400 mesh alum powders and 100 mesh borneol powder are made respectively;
S4, it takes cloves extracting solution and root of Dahurain angelica extracting solution to mix, is poured slowly into borneol powder, is stirred continuously complete to borneol powder Material, is then poured slowly into alum powder, is stirred until homogeneous by dissolution, and medicinal mixture is made;
S5, it takes the vaseline of formula ratio and lanolin to be mixed and heated to 55~60 DEG C of meltings, pours into the drug of formula ratio In mixture, it is stirred continuously to room temperature, it is bottled after mixing, 100g/ bottles, the ointment for dispelling body odour is made.
Embodiment 2, the present invention dispel the Chinese medicine composition, ointment and preparation method of body odour:
Chinese medicine preparation: cloves 1.5kg, root of Dahurain angelica 1.5kg, alum 1.5kg and borneol 0.5kg.
Medical ointment prescription: medicinal mixture 300g, matrix 700g, the matrix is by vaseline and lanolin by weight 1: 0.4 composition.
Ointment preparation method:
The ethanol solution 13L that volume fraction is 85%, the refluxing extraction at 55 DEG C is added in S1, the cloves for taking formula ratio 1.5h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and cloves extracting solution is made;
S2, the root of Dahurain angelica for taking formula ratio crushed 40 meshes, the ethanol solution 10L that volume fraction is 80% be added, at 55 DEG C Lower refluxing extraction 3h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and root of Dahurain angelica extracting solution is made;
S3, the alum and borneol for taking formula ratio grind 400 mesh alum powders and 100 mesh borneol powder are made respectively;
S4, it takes cloves extracting solution and root of Dahurain angelica extracting solution to mix, is poured slowly into borneol powder, is stirred continuously complete to borneol powder Material, is then poured slowly into alum powder, is stirred until homogeneous by dissolution, and medicinal mixture is made;
S5, it takes the vaseline of formula ratio and lanolin to be mixed and heated to 55~60 DEG C of meltings, pours into the drug of formula ratio In mixture, it is stirred continuously to room temperature, it is bottled after mixing, 100g/ bottles, the ointment for dispelling body odour is made.
Embodiment 3, the present invention dispel the Chinese medicine composition, ointment and preparation method of body odour:
Chinese medicine preparation: cloves 1.5kg, root of Dahurain angelica 1.2kg, alum 1.2kg and borneol 0.3kg.
Medical ointment prescription: medicinal mixture 250g, matrix 750g, the matrix is by vaseline and lanolin by weight 1: 0.3 composition.
Ointment preparation method:
The ethanol solution 10L that volume fraction is 90%, the refluxing extraction at 60 DEG C is added in S1, the cloves for taking formula ratio 1.5h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and cloves extracting solution is made;
S2, the root of Dahurain angelica for taking formula ratio crushed 40 meshes, the ethanol solution 8L that volume fraction is 75% be added, at 55 DEG C Lower refluxing extraction 3h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and root of Dahurain angelica extracting solution is made;
S3, the alum and borneol for taking formula ratio grind 400 mesh alum powders and 100 mesh borneol powder are made respectively;
S4, it takes cloves extracting solution and root of Dahurain angelica extracting solution to mix, is poured slowly into borneol powder, is stirred continuously complete to borneol powder Material, is then poured slowly into alum powder, is stirred until homogeneous by dissolution, and medicinal mixture is made;
S5, it takes the vaseline of formula ratio and lanolin to be mixed and heated to 55~60 DEG C of meltings, pours into the drug of formula ratio In mixture, it is stirred continuously to room temperature, it is bottled after mixing, 100g/ bottles, the ointment for dispelling body odour is made.
Embodiment 4, the present invention dispel the Chinese medicine composition, ointment and preparation method of body odour:
Chinese medicine preparation: cloves 1.2kg, root of Dahurain angelica 1.0kg, alum 1.0kg and borneol 0.2kg.
Medical ointment prescription: medicinal mixture 250g, matrix 750g, the matrix is by vaseline and lanolin by weight 1: 0.3 composition.
Ointment preparation method:
The ethanol solution 10L that volume fraction is 90%, the refluxing extraction at 60 DEG C is added in S1, the cloves for taking formula ratio 1.5h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and cloves extracting solution is made;
S2, the root of Dahurain angelica for taking formula ratio crushed 40 meshes, the ethanol solution 8L that volume fraction is 75% be added, at 55 DEG C Lower refluxing extraction 3h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and root of Dahurain angelica extracting solution is made;
S3, the alum and borneol for taking formula ratio grind 400 mesh alum powders and 100 mesh borneol powder are made respectively;
S4, it takes cloves extracting solution and root of Dahurain angelica extracting solution to mix, is poured slowly into borneol powder, is stirred continuously complete to borneol powder Material, is then poured slowly into alum powder, is stirred until homogeneous by dissolution, and medicinal mixture is made;
S5, it takes the vaseline of formula ratio and lanolin to be mixed and heated to 55~60 DEG C of meltings, pours into the drug of formula ratio In mixture, it is stirred continuously to room temperature, it is bottled after mixing, 100g/ bottles, the ointment for dispelling body odour is made.
Comparative example 1
Compared with Example 4, the difference of this comparative example is only that: change the preparation method of ointment, specific as follows:
The ethanol solution 10L that volume fraction is 90%, the refluxing extraction at 60 DEG C is added in S1, the cloves for taking formula ratio 1.5h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and cloves extracting solution is made;
S2, the root of Dahurain angelica for taking formula ratio crushed 40 meshes, the ethanol solution 8L that volume fraction is 75% be added, at 55 DEG C Lower refluxing extraction 3h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and root of Dahurain angelica extracting solution is made;
S3, the alum and borneol for taking formula ratio grind 400 mesh alum powders and 100 mesh borneol powder are made respectively;
S4, it takes the vaseline of formula ratio and lanolin to be mixed and heated to 55~60 DEG C of meltings, then stops heating, be added The alum powder and borneol powder (being dissolved with a small amount of ethyl alcohol) of calculation amount, stir evenly, add cloves extracting solution and root of Dahurain angelica extracting solution, It is stirred continuously to room temperature, it is bottled after mixing, 100g/ bottles, ointment is made.
Comparative example 2
Compared with Example 4, the difference of this comparative example is only that: change the preparation method of ointment, specific as follows:
The ethanol solution 10L that volume fraction is 90%, the refluxing extraction at 60 DEG C is added in S1, the cloves for taking formula ratio 1.5h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and cloves extracting solution is made;
S2, the root of Dahurain angelica for taking formula ratio crushed 40 meshes, the ethanol solution 8L that volume fraction is 75% be added, at 55 DEG C Lower refluxing extraction 3h is filtered, and is concentrated into the 1/4 of original volume at 60 DEG C, and root of Dahurain angelica extracting solution is made;
S3, the alum and borneol for taking formula ratio grind 400 mesh alum powders and 100 mesh borneol powder are made respectively;
S4, it takes the vaseline of formula ratio and lanolin to be mixed and heated to 55~60 DEG C of meltings, then stops heating, pour into It in the alum powder and borneol powder (being dissolved with a small amount of ethyl alcohol) of calculation amount, stirs evenly, adds cloves extracting solution and the root of Dahurain angelica extracts Liquid is stirred continuously to room temperature, bottled after mixing, and 100g/ bottles, ointment is made.
Test example one, the present invention dispel the Detection of Stability of the ointment of body odour
Stability test is carried out to the ointment of Examples 1 to 4 and comparative example 1~2, test result is as follows table 1.
The stability test result of each ointment of table 1
From upper table 1: 1~4 ointment of the embodiment of the present invention investigates test, body by heat-resisting, cold-resistant and centrifugal stability It is that property is stablized, the bad phenomenons such as water-oil separation does not occur, be suitble to long-term storage and uses.And comparative example 1 and comparative example 2 change Having become the order of addition of material, then system stability declines, and it is investigated in test in heat-resisting and centrifugal stability and lamination occurs, Prompt preparation method of the invention that can effectively improve the stability of ointment.
The effect of test example two, the present invention dispel the ointment of body odour detection
1, general information: the volunteer with body odour 100 is included in standard: (1) the body odour patient of clinical definite;(2) not Once received the patient of operation;(3) age is gone to a doctor at 18 years old or more.Male 46 in 100 volunteers, female 54, the age 18~ 28 years old, the course of disease 6~52 months.
2, treatment method: using 4 ointment of the embodiment of the present invention be directly applied to affected part (general 1 course for the treatment of of medication is significant in efficacy, depending on Situation carries out 2,3,4 courses for the treatment of):
(1) the 1st course for the treatment of: it daily coating 1~3 time, is discontinued after 15d is used in conjunction;
(2) the 2nd courses for the treatment of: such as smelling an offensive odor, then medication 5d, daily coating 1~3 time is discontinued;
(3) the 3rd courses for the treatment of: such as smelling an offensive odor, then medication 5d, daily coating 1~3 time is discontinued;
(4) the 4th courses for the treatment of: such as smelling an offensive odor, then medication 5d, daily coating 1~3 time is discontinued.
3, therapeutic effect:
(1) by symptom degree of alleviation point: within 24 after 1. cleaning, it is effective that oxter, which can't smell stink,.2. stink mitigate or It is effective for having less malodor.3. no significant change is invalid.
(2) by Cure point: odorless is 1 grade of healing in 20d after being 1. discontinued.2. odorless is 2 grades in 30d after being discontinued It cures.3. odorless is 3 grades of healings in 60d after being discontinued.
4, result: efficacy analysis and Cure analysis are shown in Table 2, table 3.
2 100 patient's curative effects of table
3 100 patient's Cure analyses of table
From upper table 2 and table 3: the present invention dispel body odour Chinese medicine composition and ointment it is rapid-action, medication 5d is effective Rate is up to 80%, and medication 15d obvious effective rate is up to 99%, while effect is lasting, 1 course for the treatment of of medication, and cure rate is up to 80%, after 4 course for the treatment of of medication, Cure rate odorless in 60d after drug withdrawal up to 100%, and 83% patient, therefore the present invention dispels the Chinese medicine composition of body odour And medicine frequency can be effectively reduced in ointment, improve patients ' life quality.The Chinese medicine composition and ointment for dispelling body odour simultaneously are smeared Place's skin does not occur any exceptions such as itch, rubescent, bubble, hyperemia or maculopapule, to human skin safety, can be used for a long time.
The above content is a further detailed description of the present invention in conjunction with specific preferred embodiments, and it cannot be said that Specific implementation of the invention is only limited to these instructions.For those of ordinary skill in the art to which the present invention belongs, In Under the premise of not departing from present inventive concept, a number of simple deductions or replacements can also be made, all shall be regarded as belonging to of the invention Protection scope.

Claims (10)

1. a kind of Chinese medicine composition for dispelling body odour, which is characterized in that prepare raw material including following parts by weight meter: cloves 5~ 15 parts, 5~15 parts of the root of Dahurain angelica, 5~15 parts of alum and 1~5 part of borneol.
2. dispelling the Chinese medicine composition of body odour according to claim 1, which is characterized in that the preparation including following parts by weight meter Raw material: 10~15 parts of cloves, 8~12 parts of the root of Dahurain angelica, 8~12 parts of alum and 1~3 part of borneol.
3. dispelling the Chinese medicine composition of body odour according to claim 2, which is characterized in that the preparation including following parts by weight meter Raw material: 12 parts of cloves, 10 parts of the root of Dahurain angelica, 10 parts of alum and 2 parts of borneol.
4. the Chinese medicine composition of body odour is dispelled described in any one according to claim 1~3, which is characterized in that the Chinese traditional medicine composition Object is external preparation.
5. a kind of ointment for dispelling body odour, which is characterized in that prepare raw material including following parts by weight meter: according to claim 1 20~30 parts of Chinese medicine composition, 70~80 parts of the matrix of body odour are dispelled described in~3 any one.
6. dispelling the ointment of body odour according to claim 4, which is characterized in that the matrix is by vaseline and lanolin by weight Amount is than 1:(0.2~0.4) composition.
7. the preparation method that one kind dispels the ointment of body odour according to claim 5, which comprises the following steps:
Ethanol solution is added in S1, the cloves for taking formula ratio, and 1.5~2h of refluxing extraction at 55~60 DEG C is filtered, dense at 60 DEG C It is reduced to the 1/4 of original volume, cloves extracting solution is made;
S2, the root of Dahurain angelica for taking formula ratio crushed 40 meshes, and ethanol solution, 2~3h of refluxing extraction, mistake at 55~60 DEG C is added It filters, is concentrated into the 1/4 of original volume at 60 DEG C, root of Dahurain angelica extracting solution is made;
S3, the alum and borneol for taking formula ratio grind alum powder and borneol powder is made respectively;
S4, it takes cloves extracting solution and root of Dahurain angelica extracting solution to mix, is poured slowly into borneol powder, is stirred continuously completely molten to borneol powder Material, is then poured slowly into alum powder, is stirred until homogeneous by solution, and medicinal mixture is made;
S5, it takes the vaseline of formula ratio and lanolin to be mixed and heated to 55~60 DEG C of meltings, pours into medicinal mixture, constantly It stirs to room temperature, bottled after mixing, the obtained ointment for dispelling body odour.
8. dispelling the preparation method of the ointment of body odour according to claim 5, which is characterized in that in the step S1, cloves Solid-to-liquid ratio with ethanol solution is 1g:(8~13) mL, the volume fraction of the ethanol solution is 75~85%.
9. dispelling the preparation method of the ointment of body odour according to claim 5, which is characterized in that in the step S2, the root of Dahurain angelica Solid-to-liquid ratio with ethanol solution is 1g:(6~10) mL, the volume fraction of the ethanol solution is 70~80%.
10. dispelling the preparation method of the ointment of body odour according to claim 6, which is characterized in that the mesh number of the alum powder For 400 mesh, the mesh number of the borneol powder is 100 mesh.
CN201910928194.4A 2019-09-28 2019-09-28 A kind of Chinese medicine composition that dispelling body odour and its ointment and preparation method Pending CN110464752A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113521150A (en) * 2021-04-28 2021-10-22 胡浩然 Composition and ointment for treating bromhidrosis and preparation process thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
史锦东等: "腋臭的临床治疗 ", 《华北煤炭医学院学报》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113521150A (en) * 2021-04-28 2021-10-22 胡浩然 Composition and ointment for treating bromhidrosis and preparation process thereof

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Application publication date: 20191119