CN106728166A - Treat the Chinese medicine composition of eczema - Google Patents

Treat the Chinese medicine composition of eczema Download PDF

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CN106728166A
CN106728166A CN201611199862.7A CN201611199862A CN106728166A CN 106728166 A CN106728166 A CN 106728166A CN 201611199862 A CN201611199862 A CN 201611199862A CN 106728166 A CN106728166 A CN 106728166A
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parts
oil
chinese medicine
medicine composition
eczema
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CN106728166B (en
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李俐
李雪
吕达
刘秀芳
孙帆
孙一帆
任娜
付亚冰
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Zibo Hi Tech Industrial Development Zone Biological Medicine Research Institute
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to a kind of Chinese medicine composition for treating eczema, belong to technical field of traditional Chinese medicine preparation.The Chinese medicine composition of described treatment eczema, it is prepared from the following raw materials in parts by weight:1~10 part of Olibanum extract, 10~30 parts of tea oil, 5~15 parts of cedar oil, 10~30 parts of lavender oil, 5~10 parts of amur cork tree bark extract, balance of breast wood berry extract, coconut oil or SIMMONDSIA CHINENSIS SEED OIL.The composition of Chinese medicine composition of the invention is simple, and drug effect clearly, does not contain toxic component, and with special delicate fragrance, free from extraneous odour is easy to external application to smear, and the therapeutic effect to eczema is notable, is difficult recurrence, can reach the effect treated both principal and secondary aspect of disease.

Description

Treat the Chinese medicine composition of eczema
Technical field
The present invention relates to a kind of Chinese medicine composition for treating eczema, belong to technical field of traditional Chinese medicine preparation.
Background technology
Skin as on human body with extraneous contact area the best part, influenceed by internal, conditions in vitro and environment, Easily there are various skin symptoms, eczema and dermatitis are clinically common, multiple skin diseases, account for dermatological department Number of Outpatients 15%~30%, wherein especially common with acute eczema, dermatitis, often have strong itch, exudate many, easily multiple due to it Hair, especially prolonged and repeated breaking-out and the general hair of skin damaged are more painful, are the emphasis classes of domestic and international skin disease clinic and basic research One of topic.Modern medicine proves, the pathological change of eczema is all intercellular edema (sponge is formed) and intracellular occur in epidermis Oedema, high dermis have telangiectasis, oedema and monocyte infiltration, and from clinically, eczema is often difficult to find bright Really the reason for.In recent years research thinks that eczema is Tardive allergy disease, is caused by various internal and external factors, with heredity Factor is relevant.Many so-called universal eczema, disseminated neurodermatitis etc. actually belong to atopic dermatitis (or eczema). Therefore, it has been developed that various skin medicines are adapted to and treat a variety of skin symptoms.At present, it is clinical Using based on the medicine such as antiallergy, calmness, hormone more than upper these diseases for the treatment of, such as antibiotic, Compound Dexamethasone Acetate, Cremor Mentholi Compositus, lindane frost, Econazole, Miconazole, dexamethasone class etc., these medicines possible effect when beginning to use very well, can make after smearing Some skin symptoms disappear quickly, but long-term use for a period of time after, coating position be likely to occur skin abnormality, Such as scabies secondary infection, epifolliculitis, telangiectasis, corticosteroid dermatitis, atrophoderma, pigmentation side effect, women may be used also Hair can occur and the severe reaction such as increase, and easily recur after being discontinued, effect is not ideal enough, is closed containing chemistry in this kind of medicine Western medicine into composition occupies the majority, the cream drug for also having part pure Chinese medicine composition.The general instant effect of medicine containing western medicine composition, But there is certain toxic and side effect, can also be left a trace position is smeared sometimes, to some skin sensitivities or specific crowd such as baby Child, old man, women etc. are not fully applicable;The drug side-effect of pure Chinese medicine composition is small, but general curative effect is slow, and due to mesh Preceding industrialization of Chinese medicine and standardized predicament, the price of this kind of medicine are somewhat expensive, and use cost is higher, increase medical expense Plus, bring very big economic and spiritual pressure to patient.
In sum, develop a kind of drug effect it is clear and definite, quality controllable, using in safety, the treatment eczema of low cost Drug composition is the task of top priority of current clinic skin science.
The content of the invention
It is clear and definite, quality controllable, wet using the treatment cheap and easy to get of safety, raw material it is an object of the invention to provide a kind of drug effect The Chinese medicine composition of rash dermatitis, does not contain any unknown and known indefinite toxic component of drug effect, belongs to externally applied drug, Huan Zhe Skin can be obviously improved during medication.
The Chinese medicine composition for the treatment of eczema of the present invention, it is prepared from the following raw materials in parts by weight:Frankincense 1~10 part of extract, 10~30 parts of tea oil, 5~15 parts of cedar oil, 10~30 parts of lavender oil, breast wood berry extract 40~ 80 parts, 5~10 parts of amur cork tree bark extract;
Preferred scheme one:It is prepared from the following raw materials in parts by weight:1~5 part of Olibanum extract, 10~20 parts of tea oil, 5~10 parts of cedar oil, 10~20 parts of lavender oil, 50~65 parts of berry extract of breast wood, 5~7.5 parts of amur cork tree bark extract;
Preferred scheme two:It is prepared from the following raw materials in parts by weight:5~10 parts of Olibanum extract, 20~30 parts of tea oil, 10~15 parts of cedar oil, 20~30 parts of lavender oil, 65~80 parts of berry extract of breast wood, 7.5~10 parts of amur cork tree bark extract.
The Chinese medicine composition for the treatment of eczema of the present invention, is prepared from the following raw materials in parts by weight:Frankincense is carried Take 1~10 part of thing, 10~30 parts of tea oil, 5~15 parts of cedar oil, 10~30 parts of lavender oil, 10~60 parts of coconut oil, amur cork tree 5~10 parts of bark extract;
Preferred scheme one:1~5 part of Olibanum extract, 10~20 parts of tea oil, 5~10 parts of cedar oil, lavender oil 10~ 20 parts, 40~50 parts of coconut oil, 5~7.5 parts of amur cork tree bark extract;
Preferred scheme two:5~10 parts of Olibanum extract, 20~30 parts of tea oil, 10~15 parts of cedar oil, lavender oil 20 ~30 parts, 50~60 parts of coconut oil, 7.5~10 parts of amur cork tree bark extract.
The Chinese medicine composition for the treatment of eczema of the present invention, is prepared from the following raw materials in parts by weight:Frankincense is carried Take 1~10 part of thing, 10~30 parts of tea oil, 5~15 parts of cedar oil, 10~30 parts of lavender oil, 20~60 parts of SIMMONDSIA CHINENSIS SEED OIL, Huang 5~10 parts of tiller bark extract.
Preferred scheme one:1~5 part of Olibanum extract, 10~20 parts of tea oil, 5~10 parts of cedar oil, lavender oil 10~ 20 parts, 40~50 parts of SIMMONDSIA CHINENSIS SEED OIL, 5~7.5 parts of amur cork tree bark extract.
Preferred scheme two:5~10 parts of Olibanum extract, 20~30 parts of tea oil, 10~15 parts of cedar oil, lavender oil 20 ~30 parts, 50~60 parts of SIMMONDSIA CHINENSIS SEED OIL, 7.5~10 parts of amur cork tree bark extract.
Described Olibanum extract, amur cork tree bark extract, Olibanum extract are commercially available prod.
The preparation method of the Chinese medicine composition of described treatment eczema is as follows:The raw material of formula ratio is well mixed, 1~2h is stirred under 200~300rpm, then ultrasonically treated 10~15min, 30~60min of ultraviolet sterilization, obtain final product treatment eczema The Chinese medicine composition of dermatitis.
The following is the crude drug source of Chinese medicine composition of the invention:
1st, frankincense, latin name Boszvellia carterii are resin that Xian Lan sections plant Boswellia carterii bark oozes out, point It is Somalia's frankincense and Gum Olibanum Ethiopia, is not advised in what long avette dripped that emulsus, similar round particle or be bonded into differ in size Then block, up to 2cm (frankincense pearl) or 5cm (former frankincense), has special fragrance, mildly bitter flavor.
【Extracting process】Distillation
【Function with cure mainly】Promoting blood circulation analgesic therapy, detumescence and promoting granulation.For chest impediment and cardialgia, gastral cavity pain, dysmenorrhoea Amenorrhea, the postpartum stasis of blood Zu , Disorder lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore.
2nd, tea tree, latin name Melaleuca alternifolia, Theaceae, Camellia shrub or dungarunga, leaf keratin, Long Circle or ellipse, the leaf of tea tree can tea making, seed can extract oil.
【Extracting process】Distillation
【Function with cure mainly】Tea tree extract smell delicate fragrance uniqueness is strong, and it has the antimicrobial acivity of All Pure Nature, kills The advantages of armaticity of bacterium effect, antibacterial activity, nonirritant, excellent Cutaneous permeation effect and uniqueness.Can treat and cut Scratch, very fast with rear wound healing, hemostasis power is superpower, acne and sore, whelk, mosquito bite, trick tinea etc., to seasick, carsickness Symptom is also effective in cure, can be with fixed attention.
3rd, deodar, latin name Cedrus deodara are the general designations of Pinaceae deodar platymiscium.
【Extracting process】Distillation
【Function with cure mainly】Containing very abundant essential oil in deodar, can via the mode of distillation by it from wood chip or wood Extracted in bits.Main component includes A-Cedrene, B-Cedrene, Thujopsene, Sesquiterpenes, cedrol And Wei De alcohol.Cedar oil has the medical treatment such as anti-grease leakage, anti-corrosion, sterilization, qi-restoratives, convergence, diuresis, menstruation regulating, eliminating the phlegm, desinsection and calmness Effect, can help treat acne and oiliness fash.Deodar can be used for the symptoms such as arthritis and rheumatism, can nourish whole body; Also there is the excellent effect of releiving for symptoms such as psychology and stress, anxiety, obsession and fears.
4th, lavender, latin name Lavandula angustifolia Mill, category Labiatae lavender category.Lavender exists Roman period has been just fairly common vanilla, because of its effect at most, is referred to as " after vanilla ".Doctor is just widely used in from ancient times In treatment, stem and Ye Douke are used as medicine, and are treatment cold, stomachache, the good medicine of eczema.
【Extracting process】Distillation
【Function with cure mainly】The renewal of epithelial cell tissues can be promoted, sebum secretion is balanced;It is clearing heat and detoxicating;Dissipate wind antipruritic; Treatment rubella;Mange.Sterilization, discharge of bacteria, toxin expelling, reduce insomnia, improve sleep quality, alleviate stress, pleasure mood.
5th, amur cork tree, Latin PhellodendronamurenseRUPRECHT, rutaceae amur cork tree, wampee and same Category kindred plant removes the dry bark of the universe of appearance.
【Extracting process】Water logging is extracted
【Function with cure mainly】Extract have resisting pathogenic microbes and protozoon, antibacterial, anti-cholera toxin, it is antimycotic, to B-mode Hepatitis surface antigen, antipyretic and anti-inflammatory, antihypertensive effect.
Clinical observation on the therapeutic effect:
Using Chinese medicine composition of the invention, acute, subacute dermatitis eczema patients 100 that treatment outpatient service is made a definite diagnosis, man Property 60, women 40,14~56 years old age, average 37 years old.
Treatment method:Chinese medicine composition of the invention is twice daily smeared, 2 weeks courses for the treatment of are observed 1 time for every 3 days, record curative effect And side effect.
Curative effect determinate standard is:
Cure:Skin damaged disappears, and symptom disappears;
It is effective:Skin damaged regression 60~90%, symptom is obviously improved;
Take a turn for the better:Skin damaged regression 20~59%, symptom makes moderate progress;
It is invalid:Skin damaged regression≤20%, symptom is without improvement.
Treatment results:Cure 35, effective 55, take a turn for the better 6, invalid 4, total effective rate is 90%.
Side effect:, do not find the side effect of any discomfort.
Beneficial effects of the present invention are as follows:
The formula of Chinese medicine composition of the invention has obvious with Olibanum extract, tea oil, cedar oil, lavender oil etc. The natural component of antibacterial and anti-inflammation functions is main ingredient composition, and surplus is medically acceptable solvent or auxiliary material (such as breast wood fruit extraction Thing, coconut oil, SIMMONDSIA CHINENSIS SEED OIL, amur cork tree bark extract etc.), composition is simple, and drug effect clearly, does not contain toxic component, with spy Different delicate fragrance, free from extraneous odour is easy to external application to smear, and the therapeutic effect to eczema is notable, is difficult recurrence, can reach what is treated both principal and secondary aspect of disease Effect.
Specific embodiment
The present invention is described further with reference to embodiments.
Embodiment 1
5 parts of Olibanum extract, 20 parts of tea oil, 10 parts of cedar oil, 15 parts of lavender oil, 70 parts of berry extract of breast wood, Huang 8 parts of tiller bark extract.
Weigh above material to mix in proportion, after stirring 1h under conditions of 200rpm, ultrasonically treated 10min is ultraviolet to go out Bacterium 30min, packaging, obtains final product product.
Embodiment 2
3 parts of Olibanum extract, 25 parts of tea oil, 15 parts of cedar oil, 20 parts of lavender oil, 55 parts of berry extract of breast wood, coconut palm 20 parts of seed oil, 6 parts of amur cork tree bark extract.
Weigh above material to mix in proportion, after stirring 1h under conditions of 200rpm, ultrasonically treated 12min is ultraviolet to go out Bacterium 40min, packaging, obtains final product product.
Embodiment 3
8 parts of Olibanum extract, 30 parts of tea oil, 20 parts of cedar oil, 25 parts of lavender oil, 50 parts of berry extract of breast wood, coconut palm 10 parts of seed oil, 20 parts of SIMMONDSIA CHINENSIS SEED OIL, 9 parts of amur cork tree bark extract.
Weigh above material to mix in proportion, after stirring 1h under conditions of 250rpm, ultrasonically treated 10min is ultraviolet to go out Bacterium 45min, packaging, obtains final product product.
Embodiment 4
4 parts of Olibanum extract, 13 parts of tea oil, 10 parts of cedar oil, 15 parts of lavender oil, 30 parts of coconut oil, SIMMONDSIA CHINENSIS SEED OIL 20 parts, 5 parts of amur cork tree bark extract.
Weigh above material to mix in proportion, after stirring 1h under conditions of 200rpm, ultrasonically treated 10min is ultraviolet to go out Bacterium 30min, packaging, obtains final product product.
Embodiment 5
7 parts of Olibanum extract, 15 parts of tea oil, 20 parts of cedar oil, 25 parts of lavender oil, 50 parts of coconut oil, amur cork tree bark 6 parts of extract.
Weigh above material to mix in proportion, after stirring 1h under conditions of 200rpm, ultrasonically treated 10min is ultraviolet to go out Bacterium 30min, packaging, obtains final product product.
Embodiment 6
6 parts of Olibanum extract, 20 parts of tea oil, 25 parts of cedar oil, 28 parts of lavender oil, 50 parts of SIMMONDSIA CHINENSIS SEED OIL, amur cork tree tree 5 parts of bark extract.
Weigh above material to mix in proportion, after stirring 1.5h under conditions of 200rpm, ultrasonically treated 15min is ultraviolet Sterilizing 40min, packaging obtains final product product.

Claims (5)

1. a kind of Chinese medicine composition for treating eczema, it is characterised in that:It is prepared from the following raw materials in parts by weight:Frankincense is carried Take 1~10 part of thing, 10~30 parts of tea oil, 5~15 parts of cedar oil, 10~30 parts of lavender oil, breast wood berry extract 40~80 Part, 5~10 parts of amur cork tree bark extract.
2. it is according to claim 1 treatment eczema Chinese medicine composition, it is characterised in that:By following parts by weight Raw material is made:1~10 part of Olibanum extract, 10~30 parts of tea oil, 5~15 parts of cedar oil, 10~30 parts of lavender oil, coconut Oily 10~60 parts, 5~10 parts of amur cork tree bark extract.
3. it is according to claim 1 treatment eczema Chinese medicine composition, it is characterised in that:By following parts by weight Raw material is made:1~10 part of Olibanum extract, 10~30 parts of tea oil, 5~15 parts of cedar oil, 10~30 parts of lavender oil, lotus lotus 20~60 parts of bar oil, 5~10 parts of amur cork tree bark extract.
4. it is according to claim 1 treatment eczema Chinese medicine composition, it is characterised in that:The Chinese medicine composition is Externally applied liniment, lotion or creme.
5. according to the Chinese medicine composition of any described treatment eczemas of claim 1-3, it is characterised in that:Preparation method is such as Under:The raw material of formula ratio is mixed, 1~2h is stirred under 200~300rpm, then ultrasonically treated 10~15min, ultraviolet 30~60min of sterilizing, obtains final product the Chinese medicine composition for the treatment of eczema.
CN201611199862.7A 2016-12-20 2016-12-20 Traditional Chinese medicine composition for treating eczema dermatitis Active CN106728166B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113730490A (en) * 2019-10-28 2021-12-03 深圳市远光宙科技有限公司 Preparation method of composition for relieving skin eczema symptom
CN116870081A (en) * 2023-07-17 2023-10-13 南方医科大学深圳医院 Composition for preventing and treating radiotherapy and chemotherapy related skin mucosa injury and application thereof

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Publication number Priority date Publication date Assignee Title
CN1561954A (en) * 2004-04-22 2005-01-12 上海交通大学 Skin external sterilizer
CN105168361A (en) * 2015-08-28 2015-12-23 吉林大学 Compound plant oil liniment for treating burns and scalds and preparation method of compound plant oil liniment

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN1561954A (en) * 2004-04-22 2005-01-12 上海交通大学 Skin external sterilizer
CN105168361A (en) * 2015-08-28 2015-12-23 吉林大学 Compound plant oil liniment for treating burns and scalds and preparation method of compound plant oil liniment

Non-Patent Citations (1)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113730490A (en) * 2019-10-28 2021-12-03 深圳市远光宙科技有限公司 Preparation method of composition for relieving skin eczema symptom
CN113730490B (en) * 2019-10-28 2022-03-04 深圳市远光宙科技有限公司 Preparation method of composition for relieving skin eczema symptom
CN116870081A (en) * 2023-07-17 2023-10-13 南方医科大学深圳医院 Composition for preventing and treating radiotherapy and chemotherapy related skin mucosa injury and application thereof

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