CN1682886A - External application Chinese medicine composition for treating rheumatism, rheumatoid diseases and chronic pain - Google Patents

Abstract

The externally applied Chinese medicine composition for treating rheumatism, rheumatoid diseases and chronic pain is powder or ointment mixture prepared with 16 kinds of Chinese medicinal materials, including musk, gastrodia tuber, safflower, ledebouriella root, pubescent angelica root, etc. in certain proportion. The present invention has simple preparation process, no side effect, high curative effect, wide application and other advantages. It may be used in expelling wind, cold, wetness and heat to treat rheumatism, rheumatoid diseases, cervical spondylosis, protrusion of lumbar intervertebral disc, etc. with high effective rate.

Description

The Traditional Chinese Medicine for external application compositions of treatment rheumatic and rheumatoid and chronic pain

Technical field the present invention relates to a kind of Chinese medicine composition, more particularly, relates to a kind of Traditional Chinese Medicine for external application compositions for the treatment of rheumatic and rheumatoid and chronic pain.

Background technology is well-known, and rheumatism, rheumatoid and the painful diseases that causes thereof are perplexing the mankind, serious harm whole world people's health, even because of complication death, and be difficult for curing.Existing various liniment and various oral drugs all have little effect clinically.Existing Western medicine is used multiple block therapy, perhaps comes pain management with the serious medicine of oral toxicity, but the rheumatoid textured bone exists in succession, still brings great body and mind misery to rheumatoid and chronic pain patient.

Summary of the invention the object of the present invention is to provide a kind of having no side effect, good effect, the treatment rheumatic and rheumatoid that cure rate is high and treatment time is short and the Traditional Chinese Medicine for external application compositions of various chronic pains.

In order to achieve the above object, the invention provides following technical scheme: developing a kind of Traditional Chinese Medicine for external application compositions for the treatment of rheumatic and rheumatoid and chronic pain, is the powdery or the paste mixture of multiple components, and the composition of said composition and parts by weight are: Moschus 3～15, Rhizoma Gastrodiae 10～30, Flos Carthami 12～30, Radix Saposhnikoviae 10～30, Radix Angelicae Pubescentis 10～30, Olibanum 10～30, Herba Menthae 10～18, Myrrha 12～30, Rhizoma Alismatis 12～20.Each composition fully is mixed into the fine-powdered thing or adds medical distilled water and make pastel and spread on the affected part outward, preferably the outsourcing gauze gets final product.Changed once in 6～7 hours, 6 days is a course of treatment, and can fully recover general 1～3 course of treatment.

The pharmacological action of each composition that the present invention uses is summarized as follows: Moschus (Moschus), have another name called Moschus, MOSCHUS, woods Moschus moschiferous Moschus contains muscone, muscopyridine, androgen, cholesterol and cholesterol ester, horse Moschus moschiferous Moschus contains cholesterol and cholesterol ester, former Moschus moschiferous Moschus mainly contains other ketones of macromole cyclic ketones traces such as muscone, muscopyridine, hydroxyl muscopyridine A, hydroxyl muscopyridine B, and its acrid in the mouth is warm in nature.GUIXIN, liver, spleen essence.Have the refreshment of having one's ideas straightened out, blood circulation promoting and dispersing pathogen accumulation, the alleviating pain and detumescence function can be used for traumatic injury, weighs wounded, disease such as carbuncle malignant boil.Rhizoma Gastrodiae (Rhizoma Gaastrodiae), have another name called rhizoma gastrodiae, DINGFENGCAO is followed etc., contain Gastrodine, gastrodioside, p-Hydroxybenzylalcohol, hydroxy benzaldehyde, 4-acrinyl methyl ether, cephrol, citric acid trimethyl ester, succinic acid, Palmic acid, cupreol etc., and contain gastrodia elata polysaccharide and various trace elements, its property is flat, sweet in the mouth, suffering.Return Liver Channel.Have expelling wind and removing dampness, channels sootheing and network vessel quickening, the promoting blood circulation and stopping pain function is celebrated by force with wind-expelling pain-stopping power.Flos Carthami (Flos Garthami) has another name called red blue flower, the thorn Flos Carthami, and Flos Carthami, Flos Carthami contains safflower yellow, saffloside, carthamin, carthamone and neocarthamin etc., other contains ketone and fatty oil is a safflower oil, its acrid in the mouth, little hardship, warm in nature.GUIXIN, Liver Channel.Has promoting blood circulation to restore menstrual flow, the stasis-dispelling and pain-killing function.The blood stasis that is usually used in traumatic injury is had a pain, and Flos Carthami has the merit of eliminating stasis to stop pain detumescence.Radix Saposhnikoviae (RadixSaposhnikoviae) has another name called copper and rues, and returns grass, and screen contains volatile oil, and oil includes octanal, β-bisabolence, aldehyde C-9,7-zinc alkene 4-alcohol, hexanal, cuparene and β-press folic alcohol etc.Its acrid in the mouth, sweet, warm in nature.Return bladder, lung, spleen channel.Has expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion function.Can be used for anemofrigid-damp arthralgia, the muscle arthralgia, the skin ulcer that can disappear is controlled rash, is used for the carbuncle pyogenic infections from tumour or sore.Radix Angelicae Pubescentis (Radix Angelicae Biserrata) has another name called only cunning, RADIX ANGELICAE PUBESCENTIS from Sichuan of China, and fragrant Radix Angelicae Pubescentis contains volatile component methoxyl group parsley element, thymol, cedrene, the Coumarins angelol, Humuleno, majudin etc., its acrid in the mouth, hardship, warm in nature.Return liver, kidney, urinary bladder channel.Have wind-damp dispelling, table function is separated in pain relieving.Be used for anemofrigid-damp arthralgia, soreness of waist and knee joint, in vitro tests proves that the Radix Angelicae Pubescentis decoct all has inhibitory action to escherichia coli, dysentery bacterium, Bacillus proteus etc.Olibanum (Olibanum) has another name called nipple perfume (or spice), and it pool is fragrant, bathes perfume (or spice) etc., contains resin (free boswellic acid, olibanoresene etc.) 60%～70%, natural gum (Arabic heteropolysaccharide acid calcium magnesium etc.) 27%～35%, volatile oil (racemization limonene etc.) 3%～8%.Its acrid in the mouth, hardship, slightly warm in nature.GUIXIN, liver, spleen channel.Have blood-activating and qi-promoting, inducing menstruation to relieve menalgia, functions such as detumescence and promoting granulation can be used for rheumatic arthralgia, all diseases of traumatic pain and carbuncle.Herba Menthae (HerbaMenthae) has another name called the yang invigorating dish, core Adiantum monochlamys Eaton. etc., contain volatile oil, mainly contain menthol, menthone in the volatile oil, also contain acetic acid menthone, camphene, limonene, pinene, resin, tannin, fan and reach fragrant acid, caffeic acid and multiple free amino acid etc., its acrid in the mouth, cool in nature.Return lung, Liver Channel.Have dispelling wind and heat pathogens, the clear sharp head, sore-throat relieving rash and dispersing the stagnated live-QI to relieve the stagnation of QI function, can be used for the laryngopharynx swelling and pain of wind heat Yong Sheng and the conjunctival congestion etc. of having a headache.Myrrha (Myrrha) has another name called myrrh, contains resin (heerabomyrrholic acid, myrrholic acid, commiphorinic acid, heerabomyrrhol etc.) 25%～35%, volatile oil (eugenol, between phenyl methylcarbamate, cumaldehyde, pinene etc.) 2.5%～9%, (hydrolysis gets arabinose to natural gum, galactose and xylose etc.) 57%～65%, its bitter in the mouth, suffering, property is flat.Return liver, the heart, spleen channel.Have promoting blood circulation to remove blood stasis, promoting the circulation of QI to relieve pain, detumescence and promoting granulation function, be used for all diseases and carbuncle skin infection and innominate toxic swelling due to the stagnation of QI-blood.Rhizoma Alismatis (Rhizoma Alismatis) has another name called watery diarrhea, and grandson Yu is contained multiple tetracyclic triterpene keto-alcohol derivant Alisol A, B, C and their acetas, epialisol A, alismoxide and potassium salt, alkaloid, asparagine and resin etc.Its sweet in the mouth, light, cold in nature.Return spleen, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria, the blood fat reducing merit of expelling the heat-evil and fat-reducing antiinflammatory action, this product can the sweet light profit of oozing, clearing heat and freeing strangury, You Yishui is wet for suffering from, the damp-heat accumulation person is the most suitable.Has splendid therapeutic effect by the reasonable potentiation each other of the compositions compatibility of aforementioned proportioning.

The composition of the present composition and parts by weight are preferably: Moschus 4～6, Rhizoma Gastrodiae 10～20, Flos Carthami 12～18, Radix Saposhnikoviae 10～20, Radix Angelicae Pubescentis 10～20, Olibanum 10～20, Herba Menthae 12～18, Myrrha 12～18, Rhizoma Alismatis 12～18.Its compatibility is more reasonable, and therapeutic effect is better and be easy to grasp consumption.

No matter in the compositions of the present invention be the prescription of claim 1 or 2, all also contain total amount and be the mixture of one or more arbitrary proportions of auxiliary composition Cortex Phellodendri, Radix Curcumae, rhizoma sparganic, Rhizoma Et Radix Notopterygii, Gypsum Fibrosum, Folium Mori, the Polyporus of 10～30 parts by weight.The effect of described each auxiliary composition is summarized as follows: Cortex Phellodendri (Cortex Phellodendri), have another name called bark of a cork tree skin, Cortex Phellodendri, comprise plant Chinese corktree (Phellodendron Amurense Rupr.) skin and wampee (Phellodendron Chinense Schneid) skin, the Cortex Phellodendri bark contains berberine and contains a small amount of phellodendrine, magnoflorine, limonin, obacunone and multiple sterol; Cortex clausenae lansii contains berberine, phellodendrine, magnoflorine, palmatine, lactone, sterol.Its sweet in the mouth, cold in nature.Return kidney, bladder, large intestine channel.Have heat clearing and damp drying, eliminating fire and detoxication effect.Can be used for sore swollen toxin, eczema scald, multiple pathogenic dermatophytes is had inhibitory action; Radix Curcumae (Radix Curcumae) has another name called Huang Yu, radix curcumae, contains curcumin chemical compounds, turmerone, terpinene, curcumene, nopinene, by foline, lauro lene, Flos Caryophylli alkene, beta-elemene, curcumenol etc.Its acrid in the mouth, hardship, cold in nature.GUIXIN, liver, gallbladder meridian.Have promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, depressed liver-energy dispersing and function of gallbladder promoting effect.Can be used for all diseases due to the stagnation of QI and blood; Rhizoma sparganic (Rhizoma Sparganii) contains volatile oil, and Main Ingredients and Appearance wherein is phenethanol, hydroquinone, hexadecylic acid, dehydrocostuslactone, beta-elemene, 2-furancarbinol etc.Its acrid in the mouth, hardship, property are put down.Return liver, spleen channel.Have removing blood stasis circulation of qi promoting, removing food stagnancy analgesic effect.Can be used for traumatic injury, play function of promoting blood circulation to disperse blood clots; Rhizoma Et Radix Notopterygii (Rhizoma et Radix Notopterygiri) has another name called Qiang green grass or young crops, and black powder contains volatile oil, wherein contains thujene, pinene, ocimene, terpinene, limonene, terpinenol, acetic acid bornyl ester, parsley brain etc.Its acrid in the mouth, hardship, warm in nature.Return bladder, kidney channel.Have the cold expelling of inducing sweat, expelling wind and dampness, analgesic effect.Be usually used in anemofrigid-damp arthralgia, fight mutually, having property buoyance lift sun such as arthralgia, health pain with restlessness, the merit of expelling wind and dampness with dispelling the wind and dampness pathogens; Gypsum Fibrosum (Gypsum Fibrosum) has another name called microlith, Mirabilitum crystallina, trace element such as main sulfur acid calcium and Organic substance, sulfide, iron salt, magnesium salt, its acrid in the mouth, sweet, cold in nature.Return stomach, lung meridian.Have clearing away heat-fire, the relieving restlessness effect of quenching the thirst.Be used for boil, scald, eczema etc., Gypsum Fibrosum is suitable for sore and toxic acute stage, the red and swollen heat pain or the back redness of the bursting person that do not disappear good than the Gypsum Fibrosum preparata effect with Gypsum Fibrosum; Folium Mori (Folium Mori Albae) have another name called Herba adianti myriosori, tame Mulberry, and Folium Mori contain steroidal and triterpenoid compound, flavone and glycoside thereof, coumarin and glycoside thereof, volatile oil, aminoacid and little peptide, alkaloid, organic acid and chemical compound thereof.Its bitter in the mouth, sweet, cold in nature.Return liver, lung meridian.Have dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving, cooling blood for hemostasis effect.Folium Mori have blood sugar lowering, antibacterial action, also can be used for migratory arthralgia pain, fry in shallow oil the soup fumigation and wash method; Polyporus (Polyporus) has another name called the Rhizoma Anemones flaccidae peach, and pig Poria, sclerotium contain Polyporus glucosan I, ergosterol, the acid of hydroxyl tetracosyl, crude protein and biotin etc.Its sweet in the mouth, gallbladder, property are put down.Return spleen, kidney, urinary bladder channel.Have dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving, cooling blood for hemostasis effect.Discovered in recent years this product has human body immunity improving function and antitumaous effect preferably, and being used for multiple malignant tumor such as chronic hepatitis and lung, hepatocarcinoma has certain curative effect.

Above-mentioned each auxiliary composition can according to and feelings select for use, for example: the back has sore swollen toxin or hand that scald is arranged, and can add Cortex Phellodendri, because Cortex Phellodendri has heat clearing and damp drying, eliminating fire and detoxication effect, can be used for sore swollen toxin, eczema scald, because multiple pathogenic dermatophytes is had inhibitory action; For another example: have rheumatism, and, can add rhizoma sparganic, because the volatile oil in the rhizoma sparganic has removing blood stasis circulation of qi promoting, removing food stagnancy analgesic effect with the knee joint wound.Can be used for traumatic injury, play function of promoting blood circulation to disperse blood clots.The wounded outside the health back has sore swollen toxin or hand and foot to have to scald and even has then can add Cortex Phellodendri and rhizoma sparganic wound when bleeding simultaneously, can add Polyporus again.Because human body is a complicated organism, the state of an illness is varied, adds auxiliary composition under doctor's guidance, can make therapeutic effect better, does not repeat them here, but only uses the prescription of fundamental component can cure certainly.

When the present invention assists composition in adding, when the prescription of fundamental component is in claim 2 scope, the total amount of the mixture of one or more arbitrary proportions of the auxiliary composition Cortex Phellodendri that then contains in the compositions, Radix Curcumae, rhizoma sparganic, Rhizoma Et Radix Notopterygii, Gypsum Fibrosum, Folium Mori, Polyporus is preferably 10～20 parts by weight.This content is comparatively moderate, can play expected effect.

Preferably contain guiding drug composition yellow wine in the present composition, the weight ratio of composition total weight and yellow wine is 1: 0.8～1.2.Can adopt following method manufacturing: each component through clean, dry, to be ground into granularity be micropowder more than 100 orders, fully mixes, and adds yellow wine furnishing paste in proportion.Can be made into plaster or plaster again.In other words, make guiding drug, described yellow wine (Samshu with yellow wine; Glutinous Rice Wine), be to brewage the wine that forms with rice and yeast for brewing rice wine, malt yeast etc., be yellow.The most famous with Shaoxing rice wine, contain ethanol about 15%, the alcoholic strength gentleness except that drinking, can be used as adapted Chinese medicine auxiliary material.

Compared with prior art, the present invention has raw material and is easy to get, and manufacturing process is simple, have no side effect good effect, cure rate height, advantages such as treatment time is short and be widely used can be used for treating rheumatic and rheumatoid and various chronic pain, and the wind and cold damp-heat syndrome in each joint is excreted.Do to draw the modulation back and make plaster with yellow wine, be affixed on the affected part after being heated to a little more than skin temperature, effect can be better.Use the present composition, changed 1 time in 6～7 hours, 6 days is a course of treatment, and can fully recover general 1～3 course of treatment.Only a few patient has skin to itch and rubescent by chance, is coated with red the disappearing that itch after the PIKANG SHUANG outward, can then use.

Medicine of the present invention is to the effect of rheumatism, rheumatoid and various acute and chronic pain, and through clinical trial 1,500 example, the result is as follows:

Rheumatisant's 180 examples, rheumatoid disease patient's 120 examples, cervical spondylosis patient's 200 examples, lumbar intervertebral disc patient 250 examples, scapulohumeral periarthritis patient's 250 examples, sweet property sciatica patient 200 examples, osteoarthritis patient's 300 examples.In the clinical observation of 1,500 routine patient's case system, its efficacy result is: among 1, the 500 routine patient, and male's 600 examples, women's 900 examples, wherein:

The male: 15 years old～45 years old 250 example, 46 years old～80 years old 350 example,

The women: 18 years old～40 years old 350 example, 41 years old～80 years old 550 example,

The male patient can be engaged in light, heavy physical labour and physical training person's 600 examples after treatment, female patient can be engaged in various physical works and physical training person's 900 examples that general women is engaged in after treatment.Cure rate=total the case load of healing total number of persons/clinical trial=(530+900)/1500=95.3%.

In sum, this Chinese medicine composition is more than 95% at the total effective rate of treatment rheumatism, rheumatoid disease, cervical spondylosis, lumbar intervertebral disc, scapulohumeral periarthritis, sweet property sciatica and osteoarthritis.

By specific embodiment the present invention is carried out more detailed description below the specific embodiment:

Embodiment 1 takes by weighing through cleaning, dry, pulverizing, sieves with 120 purpose stainless steel sifts, takes off micropowder under each sieve of stating weight, wherein: Moschus 5 grams, Rhizoma Gastrodiae 10 grams, Flos Carthami 20 grams, Radix Saposhnikoviae 25 grams, Radix Angelicae Pubescentis 12 grams, Olibanum 25 grams, Herba Menthae 18 grams, Myrrha 12 grams, Rhizoma Alismatis 20 grams, the above-mentioned medicine of respectively distinguishing the flavor of is fully mixed, add yellow wine 160 grams, the furnishing paste, get final product, can directly spread on the affected part.

Embodiment 2～5, and 7 prescriptions see Table 1, and the pretreatment of each medicine of distinguishing the flavor of is sieved with 120 purpose stainless steel sifts with example 1, makes the paste method with example 1, can directly spread on the affected part.

Embodiment 6,8 prescriptions see Table 1, and the pretreatment of each medicine of distinguishing the flavor of is sieved with 150 purpose stainless steel sifts with example 1, gets final product with the abundant moistening of medical distilled water, can directly spread on the affected part.

Table 1 embodiment 1～8 composite formula one is pulled the list position: gram

	Example 1	Example 2	Example 3	Example 4	Example 5	Example 6	Example 7	Example 8
									Moschus	??5	??15	??7	??3	??10	??8	??12	??10
Rhizoma Gastrodiae	??10	??20	??30	??25	??18	??22	??27	??15
									Flos Carthami	??20	??30	??15	??12	??25	??20	??22	??26
Radix Saposhnikoviae	??25	??10	??20	??15	??18	??27	??30	??24
									Radix Angelicae Pubescentis	??12	??20	??30	??25	??15	??10	??17	??24
Olibanum	??25	??13	??10	??20	??22	??15	??23	??30
									Herba Menthae	??18	??10	??13	??15	??12	??13	??16	??14
Myrrha	??12	??20	??25	??18	??22	??30	??28	??15
									Rhizoma Alismatis	??20	??13	??15	??15	??20	??15	??12	??18
Cortex Phellodendri		??10		??10
									Radix Curcumae			??10
Rhizoma sparganic		??8
									Rhizoma Et Radix Notopterygii				??10
Gypsum Fibrosum		??11			??5
									Folium Mori					??5
Polyporus					??5
									Yellow wine	??160	??195	??220	??134			??187

Annotate: Gypsum Fibrosum is a Gypsum Fibrosum in the table.

Claims (7)

1, a kind of Traditional Chinese Medicine for external application compositions for the treatment of rheumatic and rheumatoid and chronic pain is the powdery or the paste mixture of multiple components, and it is characterized in that: the composition of compositions and parts by weight are:

Moschus 3～15

Rhizoma Gastrodiae 10～30

Flos Carthami 12～30

Radix Saposhnikoviae 10～30

Radix Angelicae Pubescentis 10～30

Olibanum 10～30

Herba Menthae 10～18

Myrrha 12～30

Rhizoma Alismatis 12～20.

2, compositions according to claim 1 is characterized in that: the composition of compositions and parts by weight are:

Moschus 4～6

Rhizoma Gastrodiae 10～20

Flos Carthami 12～18

Radix Saposhnikoviae 10～20

Radix Angelicae Pubescentis 10～20

Olibanum 10～20

Herba Menthae 12～18

Myrrha 12～18

Rhizoma Alismatis 12～18.

3, compositions according to claim 1 is characterized in that: the mixture of one or more arbitrary proportions that also contains total amount in the compositions and be auxiliary composition Cortex Phellodendri, Radix Curcumae, rhizoma sparganic, Rhizoma Et Radix Notopterygii, Gypsum Fibrosum, Folium Mori, the Polyporus of 10～30 parts by weight.

4, compositions according to claim 2 is characterized in that: the mixture of one or more arbitrary proportions that also contains total amount in the compositions and be auxiliary composition Cortex Phellodendri, Radix Curcumae, rhizoma sparganic, Rhizoma Et Radix Notopterygii, Gypsum Fibrosum, Folium Mori, the Polyporus of 10～30 parts by weight.

5, compositions according to claim 2 is characterized in that: the total amount of the mixture of one or more arbitrary proportions of the auxiliary composition Cortex Phellodendri that contains in the compositions, Radix Curcumae, rhizoma sparganic, Rhizoma Et Radix Notopterygii, Gypsum Fibrosum, Folium Mori, Polyporus is 10～20 parts by weight.

6, the described compositions of one of claim 1～5 is characterized in that: contain guiding drug composition yellow wine in the compositions, the weight ratio of composition total weight and yellow wine is 1: 0.8～1.2.

7, the manufacture method of the described compositions of claim 1 is characterized in that: each component through clean, dry, to be ground into granularity be micropowder more than 100 orders, fully mixes, and adds yellow wine furnishing paste in proportion.