CN101332239A - Externally used drug for treating tinea - Google Patents
Externally used drug for treating tinea Download PDFInfo
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- CN101332239A CN101332239A CNA2008101473308A CN200810147330A CN101332239A CN 101332239 A CN101332239 A CN 101332239A CN A2008101473308 A CNA2008101473308 A CN A2008101473308A CN 200810147330 A CN200810147330 A CN 200810147330A CN 101332239 A CN101332239 A CN 101332239A
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Abstract
The invention relates to 'an external used medicine for curing tinea disease' and belongs to the technical field of traditional Chinese medicine. The medical components of the external used medicine are composed of sophora alopecuroide, sichuan aconite, milk veteh, sandarac, realgar, nidus vespae and Sanchi. The external used medicisne is mainly used for curing athelete's foot, tinea manuum and tinea diseases on other parts of body and is milky white in color, smells good, has no pollution on the clothes, good treatment effect, quick returns and can effect a radical cure on tinea diseases without any side effect. The external used medicine of the invention can cure other skin disease simultaneously. The external used medicine has wide medical resources, simple manufacture technology, convenient use, and is easy to be industrialized.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of medicine for external use for the treatment of the tinea disease.
Background technology
China is developing populous nation, particularly rural population is numerous, because the productive life environment and condition of rural population is not good, cause many people to suffer from the tinea disease at tinea pedis, the tinea manuum or other position of health to some extent, bring inconvenience to live and work, severe patient can develop into malignant changes such as skin carcinoma.The tinea disease can cause multiple disease, particularly women as can not get treating timely and effectively, and many women's vaginitis all is that the tinea disease causes, and is this pathogenic because of also can causing multiple diseases such as erysipelas, tympanitis, and has the stronger rate of catching an illness.As the saying goes " doctor does not control tinea, controls tinea and loses face ", visible tinea is a kind of persistent ailment, is difficult to cure.
Summary of the invention
At the deficiency in above-mentioned field, the invention provides a kind of medicine for external use for the treatment of the tinea disease, can effectively treat all kinds of tinea diseases, other skin class diseases also there is certain curative effect.
A kind of medicine for external use for the treatment of the tinea disease, its active ingredient is made of following components in weight percentage content: Herba Sophorae alopecuroidis extract 15-30%, Radix Aconiti juice 10-25%, Radix Astragali extract 10-20%, Platycladus orientalis (L.) Franco (Biota orientalis (L.) Endl.) 10-20%, Realgar powder 10-20%, Nidus Vespae extract 7-15%, Radix Notoginseng powder 5-15%.
Described Herba Sophorae alopecuroidis extract is the alcohol extract of natural disposition Herba Sophorae alopecuroidis seed.
Described Herba Sophorae alopecuroidis extract is a methanolic extract.
Described Radix Aconiti juice is the squeezeding juice of the fresh tuber of Radix Aconiti.
Described Radix Astragali extract is the alcohol extract of Radix Astragali dry root.
Described Radix Astragali extract is a methanolic extract.
Described Nidus Vespae extract is that Nidus Vespae is pulverized the back ethanol extraction.
The dosage form of described medicine for external use is a unguentum, and the grain graininess of described Realgar powder and Radix Notoginseng powder is the 300-500 order.
Active ingredient in the described unguentum accounts for the 8-15% of unguentum gross weight.
Also comprise emollient and penetrating agent in the described unguentum.
The present invention is on the basis of practice for many years, through updating prescription, adjusts the proportioning consumption, selects out above-mentioned seven kinds of compositions from Chinese herbal medicine for use, prepares the medicine for external use of treatment tinea disease.
Herba Sophorae alopecuroidis: the another name Herba Astragali Melilotoidis, leguminous plant herba Sophora alopecuroide and mature seed all can be used as medicine.Nature and flavor: bitter cold, poisonous.Effect: heat clearing away, dampness, pain relieving, sterilization etc.The used seed extract of making a living the sexual maturity Herba Sophorae alopecuroidis of the present invention is used as medicine.
Radix Aconiti: different name Radix Aconiti, the fresh tuber juice of ranunculaceae plant Aconitum carmichjaelii Debx..Nature and flavor: hot, poisonous.Effect: dispelling cold and dampness, pain relieving, counteracting toxic substances etc., composition: contain multiple alkaloid.
The Radix Astragali: different name, only stilbene, leguminous plant Radix Astragali dry root is used as medicine nature and flavor: temperature, nontoxic, effect: consolidating superficial resistance, diuretic, detumescence, poison holding, granulation promoting are put on flesh, and only fester, and recover blood capillary function etc.Composition: contain several amino acids, choline, folic acid, bitter principle and carbohydrate content.The present invention adopts the extract of Radix Astragali dry root.
Platycladus orientalis (L.) Franco (Biota orientalis (L.) Endl.): different name, pitch, excretory resin juice after burning for Cupressaceae plant Cacumen Platycladi trunk or branch.Nature and flavor: sweet, flat, nontoxic.Effect: control the tinea scabies, carbuncle sore, toxic swelling, erysipelas etc.Composition: contain flavonoid volatile oil, Quercetin, thujene etc.
Realgar: different name, gold stone, sulfide-based mineral Realgar Ore, powdery.Nature and flavor: arduous temperature, poisonous, effect: dry temperature is dispeled the wind, sterilization, detoxifcation, skin ulcer scabies poison etc.Composition: Containing Sulfur arsenic, other heavy metallic salt etc.
Nidus Vespae: different name, the honeybee intestinal is for Vespidae insecticide hornet or belong to nearly edge insecticide nest together.Nature and flavor are sweet flat, and are poisonous, effect: dispel the wind, counteracting toxic substances, sterilization, end effects such as carbuncle.Composition: contain Cera Flava, resin, Nidus Vespae wet goods.The present invention adopts the extract of Nidus Vespae.
Radix Notoginseng: different name, metal and stone changes, and the root of Araliaceae Panax pseudoginseng is ground into Powdered during use.Nature and flavor: bitter temperature, nontoxic, effect: hemostasis, dissipating blood stasis, detumescence, analgesic therapy, saprophytic new etc.Composition: contain Saponin, saccharide etc.
Chinese medicine thinks that the tinea disease is because damp and hot heresy is accumulate and amassed in the skin space between skin and muscles, or offends unclean thing and cause parasite caused by accumulation of damp-heat in the body; The tinea manuum is owing to experience noxious dampness, condenses due to the skin; Tinea pedis then by interior accumulate damp and hot, damp invasion of lower energizer or occupy for a long time due to the wetland contamination.So multiselect damp eliminating parasite killing.The present invention selects damp eliminating, the detoxifcation of Herba Sophorae alopecuroidis, Radix Aconiti, Platycladus orientalis (L.) Franco (Biota orientalis (L.) Endl.), Realgar, Nidus Vespae, the effect of sterilization for use, utilize the hemostasis, promoting pus discharge and tissue regeneration strengthening of the Radix Astragali and Radix Notoginseng, the effect of removing the rotten and letting fresh grow, impel tinea illness place to grow new skin as early as possible, repair the affected part, and the Radix Astragali is the good medicine of invigorating QI to consolidate the body surface resistance, can regulate the patient body situation, make its recovery from illness faster.
The present invention mainly is a medicine for external use, can adopt conventional exterior-applied formulation, as externally dressing, unguentum, immersion water preparation etc., the preferred unguentum of the present invention, unguentum are smeared conveniently, because composition and effectiveness of the present invention mostly is alcohol extract, in unguentum, dissolve in the oil phase, and in unguentum, can add some conventional emollient, penetrating agent, have and utilize the abundant absorption of skin, promote the growth of new skin active ingredient.The addition of active ingredient of the present invention in unguentum is about 8-15%, selects for use the emulsifying situation of this ratio unguentum relatively good.As make unguentum, the granularity of its powder Realgar powder and Radix Notoginseng powder is elected the 300-500 order as, make unguentum exquisiteness when smearing soft, do not have particulate sensation,, when the preparation unguentum, can also add an amount of depigmenting agent more because extract is yellow or brown, the ointment outward appearance that obtains like this presents milky, simultaneously an amount of essence can also be added,, the bad smell in the Chinese medicine can be covered like this based on plant essence.
The present invention prepares ointment, and the new clear fragrance of plant is arranged, and skin is not had twinge, slightly cooling feeling.To all ideal therapeutic effect of various tinea diseases, sooner or later respectively to smear once, a week is a course of treatment, for general slight tinea disease patient, no matter foot, hands, skin, face etc. are smeared continuously and can be cured in 5-10 days.For heavier person, can cure in general the continuous 10-20 of smearing days.All can cure in general the continuous 15-30 of smearing days for severe tinea illness.Continued after the healing to smear 3-5 days, to reach the purpose of radical cure.This medicine also has better therapeutic effect to the dermatosis of other type.
This medicine is suitable for by the patient to be accepted, no matter from abnormal smells from the patient, color, form, smears volatility, and all there is bigger change aspects such as permeability than traditional unguentum, and therapeutic effect is good, without any side effects, has pollution-freely, does not have the advantage of bad abnormal smells from the patient.
The specific embodiment
Raw material is prepared
Herba Sophorae alopecuroidis extract: natural disposition Herba Sophorae alopecuroidis seed, adopt the Chinese medicine extraction method to extract with methanol, can carry or adopt the commercially available prod certainly.
Radix Aconiti juice: fresh Aconitum carmichjaelii Debx. tuber squeezeding juice, self-control.
Radix Astragali extract: the Radix Astragali dry root, adopt the Chinese medicine extraction method to extract with methanol.
Platycladus orientalis (L.) Franco (Biota orientalis (L.) Endl.): the excretory resin juice of Cupressaceae plant Cacumen Platycladi trunk or branch burning back, self-control also can be adopted commercially available product.
Realgar powder: commercially available, granularity is 500 orders.
The Nidus Vespae extract: Nidus Vespae is pulverized the back and is extracted according to the Chinese medicine extraction method with ethanol.
Radix Notoginseng powder: commercially available, granularity is 500 orders.
Embodiment 1, active ingredient allotment
Herba Sophorae alopecuroidis extract 150g Radix Aconiti juice 200g Radix Astragali extract 100g Platycladus orientalis (L.) Franco (Biota orientalis (L.) Endl.) 200g Realgar powder 100g Nidus Vespae extract 100g Radix Notoginseng 150g
Above-mentioned raw materials can be pressed into tablet, or make effervescent tablet, put into water during use, hands, foot are soaked wherein get final product, as a small amount of vinegar of dropping in water, help sterilizing, the effect of convergence and skin Caring.
Embodiment 2, active ingredient allotment
Herba Sophorae alopecuroidis extract 300g Radix Aconiti juice 100g Radix Astragali extract 120g Platycladus orientalis (L.) Franco (Biota orientalis (L.) Endl.) 120g Realgar powder 200g Nidus Vespae extract 70g Radix Notoginseng 90g
Embodiment 3, active ingredient allotment
Herba Sophorae alopecuroidis extract 150g Radix Aconiti juice 250g Radix Astragali extract 200g Platycladus orientalis (L.) Franco (Biota orientalis (L.) Endl.) 100g Realgar powder 100g Nidus Vespae extract 150g Radix Notoginseng 50g
Embodiment 4: make unguentum
(preparation method) partly is heated to 80 ℃ with oil phase; Aqueous portion is heated to 90 ℃ and carries out sterilization in 20 minutes; Be cooled to 85 ℃; Carry out emulsifying in the water adding oil phase; Stir simultaneously, add essence when being cooled to 40 ℃, 35 ℃ stop to stir, and obtain mastic, can be distributed into bottle.
Experimental example: clinical observation
1, tinea manus and pedis patient 103 examples are accepted in outpatient service for medical treatment, effectively cure 80 examples in 21 days, effective 18 examples, and effective percentage is 95.2%.
2, symptom: the tinea pedis infringement often by beginning between toe, particularly between the 3rd, 4 toes, shows as the epidermis dipping, and slight squama or idol play phlycten.Can be divided into vesicle type, pimple squama type, dipping erosive type and hyperkeratotic pattern clinically.The symptom of three types is basic and the tinea manuum is same, and hyperkeratotic pattern forms callus shape limitation keratinization focus sometimes.Good sending out in the sufficient sole of the foot and lateral margin thereof.Often betide long, the older patient of stadium.Can chap in the surface.The surperficial sometimes squama of type person is not remarkable between toe, and symptom is very slight, is called asymptomatic type, and this type often is the bacillicarrier.Tinea pedis can acute occur because of medicine or certain stimulating factor sometimes, shows as the course of disease clinically and worsens suddenly, and inflammation is rapid, is the acute eczema sample and changes, and erosion is oozed out significantly.The tinea manuum: clinical manifestation and tinea pedis are roughly the same, but typing is obvious not as tinea pedis.From the beginning of being vesicle, later desquamation, coarse, keratinization thicken.From small pieces, be extended to sheet gradually.Often be limited to a side palm.
3, this out-patient treatment method: sooner or later respectively smear once with mastic, be 7 days a course of treatment, for general slight tinea disease patient, no matter foot, hands, skin, face etc., smeared continuously 5-10 days at least, for heavier person, general continuous smearing 10-20 days at least is for all general continuous the smearing 15-30 days at least of severe tinea illness.After the recovery from illness of tinea illness place, preferably repaste is smeared radical cure in 3-5 days.
Tinea disease medicine for external use of the present invention except that being used for hands, tinea pedis, also can be used for dermatomycosis such as tinea corporis, for other skin class disease certain curative effect is arranged also.
Claims (10)
1, a kind of medicine for external use for the treatment of the tinea disease, its active ingredient is made of following components in weight percentage content: Herba Sophorae alopecuroidis extract 15-30%, Radix Aconiti juice 10-25%, Radix Astragali extract 10-20%, Platycladus orientalis (L.) Franco (Biota orientalis (L.) Endl.) 10-20%, Realgar powder 10-20%, Nidus Vespae extract 7-15%, Radix Notoginseng powder 5-15%.
2, medicine for external use according to claim 1, described Herba Sophorae alopecuroidis extract are the alcohol extract of natural disposition Herba Sophorae alopecuroidis seed.
3, medicine for external use according to claim 2, described alcohol extract are methanolic extract.
4, medicine for external use according to claim 1, described Radix Aconiti juice are the squeezeding juice of the fresh tuber of Radix Aconiti.
5, medicine for external use according to claim 1, described Radix Astragali extract are the alcohol extract of Radix Astragali dry root.
6, medicine for external use according to claim 5, described alcohol extract are methanolic extract.
7, medicine for external use according to claim 1, described Nidus Vespae extract are that Nidus Vespae is pulverized the back ethanol extraction.
8, medicine for external use according to claim 1, the dosage form of described medicine for external use are unguentum, and the grain graininess of described Realgar powder and Radix Notoginseng powder is the 300-500 order.
9, medicine for external use according to claim 8, the active ingredient in the described unguentum accounts for the 8-15% of unguentum gross weight.
10, medicine for external use according to claim 9 also comprises emollient and penetrating agent in the described unguentum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101473308A CN101332239A (en) | 2008-08-07 | 2008-08-07 | Externally used drug for treating tinea |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008101473308A CN101332239A (en) | 2008-08-07 | 2008-08-07 | Externally used drug for treating tinea |
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| Publication Number | Publication Date |
|---|---|
| CN101332239A true CN101332239A (en) | 2008-12-31 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2008101473308A Pending CN101332239A (en) | 2008-08-07 | 2008-08-07 | Externally used drug for treating tinea |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105055554A (en) * | 2015-07-20 | 2015-11-18 | 叶盛德 | Plaster used for relieving and treating scabies |
| CN105079197A (en) * | 2015-07-20 | 2015-11-25 | 叶盛德 | Ointment for relieving and treating scabies and having cosmetic effect |
-
2008
- 2008-08-07 CN CNA2008101473308A patent/CN101332239A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105055554A (en) * | 2015-07-20 | 2015-11-18 | 叶盛德 | Plaster used for relieving and treating scabies |
| CN105079197A (en) * | 2015-07-20 | 2015-11-25 | 叶盛德 | Ointment for relieving and treating scabies and having cosmetic effect |
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Effective date of abandoning: 20081231 |
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