CN102415979A - Whitening and freckle-removing cream and preparation method thereof - Google Patents
Whitening and freckle-removing cream and preparation method thereof Download PDFInfo
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- CN102415979A CN102415979A CN2011104373159A CN201110437315A CN102415979A CN 102415979 A CN102415979 A CN 102415979A CN 2011104373159 A CN2011104373159 A CN 2011104373159A CN 201110437315 A CN201110437315 A CN 201110437315A CN 102415979 A CN102415979 A CN 102415979A
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- whitening
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- 230000002087 whitening effect Effects 0.000 title claims abstract description 28
- 239000006071 cream Substances 0.000 title claims abstract description 19
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 208000003351 Melanosis Diseases 0.000 title abstract description 11
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims abstract description 16
- 239000003814 drug Substances 0.000 claims description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 19
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 18
- 239000000463 material Substances 0.000 claims description 15
- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 claims description 14
- 239000007788 liquid Substances 0.000 claims description 14
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 claims description 12
- 238000000605 extraction Methods 0.000 claims description 10
- 238000003756 stirring Methods 0.000 claims description 10
- -1 polyoxypropylene Polymers 0.000 claims description 9
- 238000009835 boiling Methods 0.000 claims description 7
- 229920001436 collagen Polymers 0.000 claims description 7
- 229960000735 docosanol Drugs 0.000 claims description 7
- 239000004408 titanium dioxide Substances 0.000 claims description 7
- AMUTYVGRCVFCCD-UHFFFAOYSA-N 5,6-diaminopyridine-3-carboxylic acid Chemical compound NC1=CC(C(O)=O)=CN=C1N AMUTYVGRCVFCCD-UHFFFAOYSA-N 0.000 claims description 6
- 102000008186 Collagen Human genes 0.000 claims description 6
- 108010035532 Collagen Proteins 0.000 claims description 6
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 6
- 239000008367 deionised water Substances 0.000 claims description 6
- 229910021641 deionized water Inorganic materials 0.000 claims description 6
- 229930182478 glucoside Natural products 0.000 claims description 6
- 150000008131 glucosides Chemical class 0.000 claims description 6
- YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 claims description 6
- SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 6
- 229920001451 polypropylene glycol Polymers 0.000 claims description 6
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 4
- 229920001184 polypeptide Polymers 0.000 claims description 4
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 4
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 4
- 241000628997 Flos Species 0.000 claims description 3
- 235000008109 Thuja occidentalis Nutrition 0.000 claims description 3
- 230000002421 anti-septic effect Effects 0.000 claims description 3
- 238000007599 discharging Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 238000006386 neutralization reaction Methods 0.000 claims description 3
- 229920002125 Sokalan® Polymers 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 claims description 2
- 240000003243 Thuja occidentalis Species 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 7
- 235000010215 titanium dioxide Nutrition 0.000 abstract description 7
- 239000000049 pigment Substances 0.000 abstract description 4
- 230000005808 skin problem Effects 0.000 abstract description 3
- 230000015572 biosynthetic process Effects 0.000 abstract description 2
- 230000017531 blood circulation Effects 0.000 abstract description 2
- 230000001737 promoting effect Effects 0.000 abstract description 2
- 230000001105 regulatory effect Effects 0.000 abstract description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 abstract 2
- 206010067982 Butterfly rash Diseases 0.000 abstract 1
- 235000007516 Chrysanthemum Nutrition 0.000 abstract 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 abstract 1
- 206010014970 Ephelides Diseases 0.000 abstract 1
- 241000736211 Platycladus Species 0.000 abstract 1
- 244000046146 Pueraria lobata Species 0.000 abstract 1
- 235000010575 Pueraria lobata Nutrition 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 241000954737 Thuja sutchuenensis Species 0.000 abstract 1
- 206010008570 Chloasma Diseases 0.000 description 6
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 6
- 208000037259 Amyloid Plaque Diseases 0.000 description 3
- 241000218636 Thuja Species 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 239000012567 medical material Substances 0.000 description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 210000004927 skin cell Anatomy 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000003643 water by type Substances 0.000 description 2
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 description 1
- 229910000004 White lead Inorganic materials 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 229940025084 amphetamine Drugs 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000003915 cell function Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000000498 cooling water Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000007872 degassing Methods 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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- Cosmetics (AREA)
Abstract
The invention discloses whitening and freckle-removing cream and a preparation method thereof. The whitening and freckle-removing Chinese medicinal preparation comprises the following components in percentage by weight: 5 to 55 percent of root of kudzu vine, 15 to 35 percent of platycladus, 5 to 15 percent of rehmannia root, 5 to 45 percent of yam, 15 to 20 percent of thuja sutchuenensis and 5 to 10 percent of chrysanthemum. The cream provided by the invention can inhibit the formation of melanin while exerting a comprehensive regulating whitening and freckle-removing effect by promoting blood circulation, removing stasis, clearing heat and detoxifying the cream can be applied conveniently, and nano titanium white is added at the same time for achieving instant whitening effect. After the cream is used continuously for 28 days, the skin problems aroused by freckles, butterfly rash, age pigment and other chromatosis can be solved.
Description
Technical field
The invention belongs to the cosmetics technical field, be specifically related to a kind of whitening and speckle dispelling Chinese medicine preparation with and preparation method thereof.
Background technology
Whitening and speckle dispelling is the target that the women pursued that great majority are liked to be beautiful, and the beauty treatment circle almost is used as unique effective whitening cosmetics to preparation mercurous, hydroquinone.Contain forbidden amphetamine and cross and take effect in ten thousand times hydrargyrum and one week of chemical compound speckle dispelling thereof, toxicity is gathered and is caused countless consumers face cell downright bad, stays the blue patch that can not cure; The amount of limiting the use of of hydroquinone is 0.02%, and the hydroquinone that surpasses the amount of limiting the use of hundreds of times just has positive effect, but if life-time service can be repent forever staying abnormal white piece on the face.Therefore, how to obtain the problem that safe and effective whitening and speckle dispelling material is a puzzlement beauty and make-up industry always.
Summary of the invention
The objective of the invention is the deficiency to prior art, a kind of Chinese medicine preparation of whitening and speckle dispelling safely and effectively is provided, effectively solve the calm skin problem that causes of pigments such as chloasma, butterfly spot, senile plaque, it is easy to use, and effect is remarkable.
Another object of the present invention provides the method for preparing of this whitening and spot eliminating cream.
The present invention realizes above-mentioned purpose through following technical scheme:
A kind of whitening and speckle dispelling Chinese medicine preparation is characterized in that being made up of the component of following percetage by weight: Radix Puerariae 5-55%, Cacumen Platycladi 15-35%, Rhizoma Phragmitis 5-15%, Rhizoma Dioscoreae 5-45%, arborvitae 15-20%, Flos Chrysanthemi 5-10%.
The method for preparing of whitening and speckle dispelling Chinese medicine preparation may further comprise the steps: with each Chinese medicine proportional mixing, add the water logging bubble, be heated to boiling and keep constant temperature, leach medicinal liquid; Medicinal residues add water in addition, are heated to the boiling slow fire once more and decoct, and leach medicinal liquid, merge twice medicinal liquid after, be condensed into the Chinese medicine extraction concentrated solution.Preferred extraction scheme is that medical material gross weight 100 grams pulverize, and adds deionized water 200 grams and soaks 24 hours, is heated to boiling then and keeps constant temperature 1 hour, leaches medicinal liquid.Medicinal residues add 100 gram deionized waters in addition, and reheat decocts 30 minutes to boiling, and the elimination medicinal residues with the combining medicine that filters for twice, are condensed into 100 gram Chinese medicine extraction concentrated solutions.
A kind of whitening and spot eliminating cream, form by the component of following percetage by weight:
Chinese medicine extraction concentrated solution 10.0%, polyoxypropylene glucoside 3.0%, glycerol monostearate 1.5%, spermol 5%, glycerol 2.0%, collagen pentapeptide 3.0%, iso-octyl palmitate 4.0%, nanometer titanium dioxide 4.0%, docosanol 5.0%, carbopol 940 0.3%, triethanolamine 0.3%, antiseptic 0.3%, surplus are deionized water.
A kind of method for preparing of whitening and spot eliminating cream may further comprise the steps:
(1) under stirring, in water, spread and add carbopol, be stirred to transparently, be heated into the water material, subsequent use;
(2) be mixed and heated to 85 ℃ to polyoxypropylene glucoside, glycerol monostearate, spermol, glycerol, iso-octyl palmitate as the oil phase raw material;
(3) stirring is mixed with the water material in oil phase raw material heating back, adds the triethanolamine neutralization, adds nanometer titanium dioxide and docosanol mixture again; Constant temperature stirs postcooling to 50 ℃, adds collagen polypeptide again, stirs; Outgas into auxiliary material liquid under the vacuum, be cooled to 45 ℃;
(4) Chinese medicine extraction liquid is added in the auxiliary material liquid of step (3) gained, keep vacuum outgas, continue to be cooled to 40 ℃, discharging.
Compared with prior art, the present invention has following beneficial effect:
1. whitening and spot eliminating cream provided by the present invention not only can suppress melanic formation, and blood circulation promoting and blood stasis dispelling is arranged simultaneously, heat-clearing and toxic substances removing, and the metabolic effect of chafe reaches the whitening and speckle dispelling effect of comprehensively regulating.
The present invention select easy to carry, the cream cream type of smearing easily.Can not get into eyes during use, prescription adds the nano grade titanium white lead to reach instantaneous whitening effect, is popular.
3. add special penetrating agent-collagen polypeptide close, improve the Skin Cell function with the Skin Cell structure.
Whitening and spot eliminating cream provided by the present invention was used 28 days continuously, can eliminate the calm skin problem that causes of pigments such as chloasma, butterfly spot, senile plaque.
The present invention verifies the beneficial effect of the present invention aspect whitening and speckle dispelling through clinical experimental study.
The specific embodiment
Below further specify technical scheme of the present invention through concrete embodiment.
Embodiment 1
The preparation of Chinese medicine concentrated solution:
Radix Puerariae 40 g, Cacumen Platycladi 15 g, Rhizoma Phragmitis 10 g, Rhizoma Dioscoreae 10 g, arborvitae 15g, Flos Chrysanthemi 10g.Merge medical material 100 g and pulverize, add deionized water 200 g and soaked 24 hours, be heated to boiling then and kept constant temperature 1 hour, leach medicinal liquid.Medicinal residues add 100 g deionized waters in addition, and reheat decocts 30 minutes to the slow fire that seethes with excitement, the elimination medicinal residues, and the combining medicine with filtering for twice is condensed into 100 g Chinese medicine extraction concentrated solutions.
The preparation of whitening and spot eliminating cream:
The ratio of each material is according to following percentage by weight: Chinese medicine extraction concentrated solution 10.0%, polyoxypropylene glucoside 3.0%, glycerol monostearate 1.5%, spermol 5%, glycerol 2.0%, collagen polypeptide 3.0%, iso-octyl palmitate 4.0%, nanometer titanium dioxide 4.0%, docosanol 5.0%, carbopol 940 0.3%, triethanolamine 0.3%, antiseptic 0.3%, surplus are deionized water.
In the water pot, add deionized water, under 400 rpm high-speed stirred, spread and add carbopol 940, and be stirred to transparently, be warming up to 85 ℃ then as the water material, subsequent use.
Docosanol mixes with nanometer titanium dioxide, is ground to evenly.
Polyoxypropylene glucoside, glycerol monostearate, spermol, glycerol, iso-octyl palmitate, be mixed and heated to 85 ℃ as the oil phase material.
In the vacuum emulsification pot, add the slowly suction water mixing stirring then of oil phase material, homogenizing 4 minutes adds the triethanolamine neutralization, adds nanometer titanium dioxide and docosanol mixture then, and constant temperature stirred 30 minutes, opened cooling water.
Liquid is cooled to 50 ℃, adds collagen pentapeptide, stirs, and is evacuated to 10 millimetress of mercury, the degassing.
45 ℃ add Chinese medicine concentrated solution and other component down, continue cooling and keep vacuum outgas.
Be cooled to 40 ℃, discharging obtains whitening and spot eliminating cream.
Activity experiment:
The object of observation: 20-45 years old ages middle-aged women.Choosing is facial to have middle aged women 106 examples of pigments such as in various degree chloasma, butterfly spot, senile plaque.
Observational technique: cream frost 3 ~ 5 grams that getting embodiment 1 after washing one's face every morning is provided are applied to spotted on the face position, sleep preceding repaste evening once, and 28 days is a course of treatment.
Criterion of therapeutical effect: 1. recovery from illness: chloasma disappears basically; 2. produce effects: chloasma disappears more than 50%; 3. effective: chloasma disappears more than 10% or the patch color changes light; 4. invalid: no change before and after the treatment.
Therapeutic effect such as table 1:
Table 1
| Divide into groups | The example number | Recovery from illness | Produce effects | Effectively | Invalid | Total effective rate |
| Embodiment 1 whitening and spot eliminating cream | 106 | 89 | 10 | 5 | 2 | 95% |
Claims (4)
1. a whitening and speckle dispelling Chinese medicine preparation is characterized in that being made up of the component of following percetage by weight: Radix Puerariae 5-55%, Cacumen Platycladi 15-35%, Rhizoma Phragmitis 5-15%, Rhizoma Dioscoreae 5-45%, arborvitae 15-20%, Flos Chrysanthemi 5-10%.
2. the method for preparing of the said whitening and speckle dispelling Chinese medicine preparation of claim 1 is characterized in that comprising the steps: with each Chinese medicine proportional mixing, adds the water logging bubble, is heated to boiling and keeps constant temperature, leaches medicinal liquid; Medicinal residues add water in addition, are heated to the boiling slow fire once more and decoct, and leach medicinal liquid, merge twice medicinal liquid after, be condensed into the Chinese medicine extraction concentrated solution.
3. whitening and spot eliminating cream is characterized in that being made up of the component of following percetage by weight:
Chinese medicine extraction concentrated solution 10.0%, polyoxypropylene glucoside 3.0%, glycerol monostearate 1.5%, spermol 5%, glycerol 2.0%, collagen pentapeptide 3.0%, iso-octyl palmitate 4.0%, nanometer titanium dioxide 4.0%, docosanol 5.0%, carbopol 940 0.3%, triethanolamine 0.3%, antiseptic 0.3%, surplus are deionized water.
4. the method for preparing of a whitening and spot eliminating cream is characterized in that may further comprise the steps:
(1) under stirring, in water, spread and add carbopol, be stirred to transparently, be heated into the water material, subsequent use;
(2) be mixed and heated to 85 ℃ to polyoxypropylene glucoside, glycerol monostearate, spermol, glycerol, iso-octyl palmitate as the oil phase material;
(3) stirring is mixed with the water material in oil phase material heating back, adds the triethanolamine neutralization, adds nanometer titanium dioxide and docosanol mixture again; Constant temperature stirs postcooling to 50 ℃, adds collagen polypeptide again, stirs; Outgas into auxiliary material liquid under the vacuum, be cooled to 45 ℃;
(4) the Chinese medicine extraction concentrated solution is added in the auxiliary material liquid of step (3) gained, keep vacuum outgas, continue to be cooled to 40 ℃, discharging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110437315 CN102415979B (en) | 2011-12-23 | 2011-12-23 | Whitening and freckle-removing cream |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110437315 CN102415979B (en) | 2011-12-23 | 2011-12-23 | Whitening and freckle-removing cream |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102415979A true CN102415979A (en) | 2012-04-18 |
| CN102415979B CN102415979B (en) | 2013-01-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110437315 Expired - Fee Related CN102415979B (en) | 2011-12-23 | 2011-12-23 | Whitening and freckle-removing cream |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102415979B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150313835A1 (en) * | 2014-05-05 | 2015-11-05 | Access Business Group International Llc | Compositions including a botanical extract and methods of using the same in skin whitening and skin lightening applications |
| CN106491427A (en) * | 2016-11-08 | 2017-03-15 | 广州生美生物科技有限公司 | A kind of Radix Ginseng Rubra compositionss with moment whitening and preparation method thereof and application |
| CN109350579A (en) * | 2018-12-28 | 2019-02-19 | 广州市科能化妆品科研有限公司 | Skin-lightening cosmetic additive and the awake skin dew of whitening and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101390818A (en) * | 2007-09-21 | 2009-03-25 | 罗蔚 | Pimple removing scream |
-
2011
- 2011-12-23 CN CN 201110437315 patent/CN102415979B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101390818A (en) * | 2007-09-21 | 2009-03-25 | 罗蔚 | Pimple removing scream |
Non-Patent Citations (2)
| Title |
|---|
| 徐进 等: "葛根在化妆品中的应用初探", 《中国野生植物资源》 * |
| 赵会芝 等: "侧柏叶黄酮雪花膏配方研制及美白效果评价", 《安徽农业科学》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150313835A1 (en) * | 2014-05-05 | 2015-11-05 | Access Business Group International Llc | Compositions including a botanical extract and methods of using the same in skin whitening and skin lightening applications |
| US9801809B2 (en) * | 2014-05-05 | 2017-10-31 | Access Business Group International Llc | Compositions including a botanical extract and methods of using the same in skin whitening and skin lightening applications |
| CN106491427A (en) * | 2016-11-08 | 2017-03-15 | 广州生美生物科技有限公司 | A kind of Radix Ginseng Rubra compositionss with moment whitening and preparation method thereof and application |
| CN109350579A (en) * | 2018-12-28 | 2019-02-19 | 广州市科能化妆品科研有限公司 | Skin-lightening cosmetic additive and the awake skin dew of whitening and preparation method thereof |
| CN109350579B (en) * | 2018-12-28 | 2022-03-11 | 广州市科能化妆品科研有限公司 | Whitening cosmetic additive, whitening skin-refreshing lotion and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN102415979B (en) | 2013-01-16 |
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