CN102370739A - Compound propolis composition for treating whitecomb of chickens and preparation method thereof - Google Patents

Compound propolis composition for treating whitecomb of chickens and preparation method thereof Download PDF

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Publication number
CN102370739A
CN102370739A CN2011103068445A CN201110306844A CN102370739A CN 102370739 A CN102370739 A CN 102370739A CN 2011103068445 A CN2011103068445 A CN 2011103068445A CN 201110306844 A CN201110306844 A CN 201110306844A CN 102370739 A CN102370739 A CN 102370739A
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parts
weight
radix
whitecomb
preparation
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CN102370739B (en
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周庆福
刘文利
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Qingdao Lvman Bioengineering Co Ltd
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Qingdao Lvman Bioengineering Co Ltd
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Abstract

The invention provides a compound propolis composition for treating whitecomb of chickens and a preparation method thereof, relating to the field of poultry medicine. The invention aims to provide a compound propolis composition for treating whitecomb of chickens, which is reasonable in prescription and simple to prepare, and a preparation method thereof. The specific components and the preparation method are as follows: (1) respectively carrying out ultrafine crushing on each component in the prescription, and sieving with a 700-mesh sieve; (2) weighing 15-35 parts by weight of propolis, 10-35 parts by weight of Chinese pulsatilla and 15-30 parts by weight of kuh-seng, and mixing for 5-10 minutes until the components are uniformly mixed; (3) weighing 10-25 parts by weight of Baikal skullcap root, 10-35 parts by weight of agrimony, 10-35 parts by weight of sophora flower and 10-35 parts by weight of agrimony, and mixing for 5-10 minutes until the components are uniformly mixed; and (4) merging the compositions prepared in the steps (2) and (3), and continuing to mix for 10-15 minutes until the compositions are uniformly mixed. The compound propolis composition is reasonable in prescription and simple to prepare, and has the advantages of no toxic or side effect, no pollution, no medicine residue and no medicine resistance; due to ultrafine crushing, the bioavailability is high, and the curative effect is extremely remarkable; and clinical application proves that the compound propolis composition has a specially good effect on the treatment of whitecomb of chickens.

Description

A kind of compound bee-glue composition of treating chicken whitecomb and preparation method thereof
Technical field
The present invention relates to fowl medicine field, particularly a kind of compound bee-glue composition of treating chicken whitecomb and preparation method thereof.
Background technology
Chicken whitecomb is a kind of cytozoicus property protozoacide that is caused by chicken Ka Shi coccidium syphilidis.The chicken of various ages and kind all can infect, and the highest with the chicken sickness rate in age in 3-6 week, the mortality rate that is in a bad way can be up to 50%-80%.It is characterized in that anemia, diarrhoea, whole body extensive bleeding, egg drop reduction, weightening finish slow down etc.This disease summer and autumn pilosity is one of principal disease of harm poultry husbandry.
The pathogen of primary disease is a chicken Ka Shi coccidium syphilidis, and its generation and popular and the activity storehouse midge have direct relation.This disease almost spreads all over all countries of raising chickens of the world, distributes very extensively.At present, treat this disease the most frequently used be Chinese medicine and antiparasitic, Chinese medicine is because its prescription is unreasonable or just simple the pulverizing, and particle diameter is excessive, and drug release is slower, causes its bioavailability lower, clinical effectiveness is not fine; And various anti-parasite medicines such as compound recipe Thailand go out only, sulphaquinoxaline, Robenidine, Pyrimethamine etc. are because prolonged and repeated use; Cause this pathogenic microorganism that medicine has been produced drug resistance; Reduced curative effect; And drug residue does not reach nuisanceless requirement in animal product, has influenced the outlet of animal products and people's health.
Therefore researching and developing a kind of drug residue free of chicken whitecomb, generations that have no drug resistance, the significant specific medicament of clinical effectiveness of treating is one of this field scientific research technical staff urgency new problem to be solved.
Summary of the invention
The objective of the invention is to overcome above-mentioned weak point, provide that a kind of reasonable recipe, preparation are simple, micronizing, bioavailability are high, effect obviously, have no drug resistance and the compound bee-glue composition of effective treatment chicken whitecomb of drug residue and preparation method thereof.
For realizing above-mentioned purpose; The embodiment that the present invention adopted is following: a kind of compound bee-glue composition of treating chicken whitecomb, by following component by weight mixed preparing form: propolis 15-35 part, Radix Pulsatillae 10-35 part, Radix Sophorae Flavescentis 15-30 part, Radix Scutellariae 10-25 part, Flos Sophorae 10-35 part, Herba Agrimoniae 10-35 part.
Said various component optimum ratio amount is: 25 parts of propolis, 25 parts of the Radix Pulsatillaes, 20 parts of Radix Sophorae Flavescentiss, 15 parts of Radix Scutellariaes, 20 parts in Flos Sophorae, 25 parts of Herba Agrimoniaes.
A kind of method for preparing of treating the compound bee-glue composition of chicken whitecomb, carry out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Radix Pulsatillae 10-35 part, Radix Sophorae Flavescentis 15-30 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Scutellariae 10-25 part, Flos Sophorae 10-35 part, Herba Agrimoniae 10-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
The medicinal property of each component is following:
Propolis: bitter, hot, cold, return spleen, stomach warp, have the function of anti-inflammation, antalgesic-antipruritic, promotion tissue regeneration, raising immunity, antiallergic oxidation, hemostasis, protection gastrointestinal mucosa.
The Radix Pulsatillae: bitter, cold, return stomach, large intestine channel, have the function of heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery; Cure mainly toxic-heat and blood stasis, damp and hot intestinal Huang etc.
Radix Sophorae Flavescentis: bitter, cold, GUIXIN, liver, stomach, large intestine, urinary bladder channel have that heat clearing and damp drying, parasite killing go to amass, the function of diuretic; Cure mainly damp-heat dysentery, jaundice, edema, scabies etc.
Flos Sophorae: bitter, be slightly cold, return large intestine, Liver Channel, have the function of cooling blood for hemostasis, purging liver-fire; Cure mainly have blood in stool, dysentery, metrorrhagia, liver-heat conjunctival congestion etc.
Radix Scutellariae: bitter, cold, return lung, gallbladder, spleen, large intestine, small intestine meridian, have heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive function; Cure mainly that cough due to lung-heat, gastrointestinal are damp and hot, dysentery, jaundice, hyperpyrexia are greedyly drunk, have blood in stool, epistaxis, conjunctival congestion and swelling pain, carbuncle sore tumefacting virus, frequent fetal movement etc.
Herba Agrimoniae: bitter, puckery, flat, GUIXIN, Liver Channel have astringing to arrest bleeding, dysentery relieving, antidotal function; Cure mainly have blood in stool, hematuria, haematemesis, epistaxis, dysentery, carbuncle sore tumefacting virus etc.
More than all flavor Chinese medicine according to the Chinese medical theory compatible combination, to the pathogenic microorganism and the clinical symptoms of chicken whitecomb, the effect of performance treating both the principal and secondary aspects of a disease.
The invention has the beneficial effects as follows: reasonable recipe, preparation is simple, and substep mixes more even; Chinese medicine composition is pollution-free, no drug residue, have no drug resistance, and cost is low, and it is wide to draw materials, and micronizing, bioavailability are high, can also can drink water the curative effect highly significant by spice.The present invention is according to Chinese veterinarian's traditional theory; Optimize this Six-element Chinese medicine, and make them form pure Chinese powder medicine according to optimum ratio, clinical practice proves; The treatment chicken whitecomb there is specially good effect; And make its product reach nuisanceless requirement, satisfy the export standard of product, guaranteed that effectively people's is healthy.
The specific embodiment
Below in conjunction with preferred embodiment, to details are as follows according to the specific embodiment provided by the invention:
Embodiment 1
A kind of compound bee-glue composition of treating chicken whitecomb and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 150 parts of propolis, 100 parts of the Radix Pulsatillaes, 150 parts of Radix Sophorae Flavescentiss by weight, mix 5-10 minute to even;
(3) take by weighing 100 parts of Radix Scutellariaes, 100 parts in Flos Sophorae, 100 parts of Herba Agrimoniaes by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 2
A kind of compound bee-glue composition of treating chicken whitecomb and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 200 parts of propolis, 150 parts of the Radix Pulsatillaes, 200 parts of Radix Sophorae Flavescentiss by weight, mix 5-10 minute to even;
(3) take by weighing 200 parts of Radix Scutellariaes, 200 parts in Flos Sophorae, 200 parts of Herba Agrimoniaes by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Embodiment 3
A kind of compound bee-glue composition of treating chicken whitecomb and preparation method thereof: carry out as follows: (every part by 10g)
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing 350 parts of propolis, 350 parts of the Radix Pulsatillaes, 300 parts of Radix Sophorae Flavescentiss by weight, mix 5-10 minute to even;
(3) take by weighing 250 parts of Radix Scutellariaes, 350 parts in Flos Sophorae, 350 parts of Herba Agrimoniaes by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
Clinical trial:
With the ill poultry of product feeding of the present invention etc., a day dose is: by the every 100g of the present invention, spice 120kg feeds, drinking-water 200kg, every day 2-3 time, logotype 3-5 day; Oral back reaches the purpose of treatment disease through gastrointestinal absorption.
Table is the field applicable cases contrast of the present invention and other medicines treatment chicken whitecomb:
Numbering Group Mortality rate % Cure rate % Symptom rate % is arranged during end
I The blank group 24.9 51.4 23.7
II The BAIGUAN spirit is loose and is organized 11.2 80.1 8.7
III Chinese medicine composition of the present invention 5.6 90.5 3.9
This clinical effectiveness is through statistical analysis, and present composition treatment group is loose to organize with the BAIGUAN spirit and compared difference extremely significantly (P<0.01) aspect the cure rate.
Above-mentioned detailed description of compound bee-glue composition of this treatment chicken whitecomb and preparation method thereof being carried out with reference to embodiment; Be illustrative rather than determinate; Can enumerate out several embodiment according to institute's limited range; Therefore in the variation and the modification that do not break away under the general plotting of the present invention, should belong within protection scope of the present invention.

Claims (3)

1. compound bee-glue composition of treating chicken whitecomb, it is characterized in that by following component by weight mixed preparing form: propolis 15-35 part, Radix Pulsatillae 10-35 part, Radix Sophorae Flavescentis 15-30 part, Radix Scutellariae 10-25 part, Flos Sophorae 10-35 part, Herba Agrimoniae 10-35 part.
2. a kind of compound bee-glue composition of treating chicken whitecomb according to claim 1 is characterized in that said various component optimum ratio amount is: 25 parts of propolis, 25 parts of the Radix Pulsatillaes, 20 parts of Radix Sophorae Flavescentiss, 15 parts of Radix Scutellariaes, 20 parts in Flos Sophorae, 25 parts of Herba Agrimoniaes.
3. the method for preparing of the compound bee-glue composition of a treatment chicken whitecomb according to claim 1 and 2 is characterized in that carrying out as follows:
(1) the various compositions in the prescription is crossed 700 mesh sieves after the micronizing respectively;
(2) take by weighing propolis 15-35 part, Radix Pulsatillae 10-35 part, Radix Sophorae Flavescentis 15-30 part by weight, mix 5-10 minute to even;
(3) take by weighing Radix Scutellariae 10-25 part, Flos Sophorae 10-35 part, Herba Agrimoniae 10-35 part by weight, mix 5-10 minute to even;
(4) merge the compositions that above-mentioned (2), (3) step make, continue to mix 10-15 minute to even.
CN2011103068445A 2011-10-12 2011-10-12 Compound propolis composition for treating whitecomb of chickens and preparation method thereof Expired - Fee Related CN102370739B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2599160B2 (en) * 1987-12-26 1997-04-09 日清製粉株式会社 Preventive and therapeutic agent for staphylococcal disease in chickens
CN101670012A (en) * 2009-09-18 2010-03-17 天津诺康动物药业有限公司 Traditional Chinese medicine composite for treating chicken histomoniasis and preparation method thereof
CN101697774A (en) * 2009-07-24 2010-04-28 王直军 Traditional Chinese medicine feed additive for treating chicken coccidiosis
CN102038093A (en) * 2010-09-02 2011-05-04 吴艳霞 Traditional Chinese medicinal feed additive for treating chicken coccidiosis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2599160B2 (en) * 1987-12-26 1997-04-09 日清製粉株式会社 Preventive and therapeutic agent for staphylococcal disease in chickens
CN101697774A (en) * 2009-07-24 2010-04-28 王直军 Traditional Chinese medicine feed additive for treating chicken coccidiosis
CN101670012A (en) * 2009-09-18 2010-03-17 天津诺康动物药业有限公司 Traditional Chinese medicine composite for treating chicken histomoniasis and preparation method thereof
CN102038093A (en) * 2010-09-02 2011-05-04 吴艳霞 Traditional Chinese medicinal feed additive for treating chicken coccidiosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王学慧: "鸡住白细胞原虫病的中西医结合治疗试验", 《江苏农业科学》 *

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