CN102366093A - Composite slimming health food - Google Patents
Composite slimming health food Download PDFInfo
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- CN102366093A CN102366093A CN2011102847771A CN201110284777A CN102366093A CN 102366093 A CN102366093 A CN 102366093A CN 2011102847771 A CN2011102847771 A CN 2011102847771A CN 201110284777 A CN201110284777 A CN 201110284777A CN 102366093 A CN102366093 A CN 102366093A
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Abstract
The invention discloses a composite slimming health food. The composite slimming health food is prepared from the following raw materials, by weight, 4-20 parts of white kidney bean extracts and 80-96 parts of L-arabinose. According to the composite slimming health food, the activity of sucrase in vivo can be inhibited by L-arabinose, so the digestion and the absorption of sucrose in an alimentary canal are reduced, and the ingestion of energy in foods is reduced; and the activity of amylase in vivo can be inhibited by the white kidney bean extracts, so the digestion and the absorption of starch in the foods are reduced, and the energy ingestion is reduced. Above two natural products which do not influence the absorption of other nutrients of proteins, vitamins and the like and are composited and proportioned allow the advantages of the two natural products on slimming to be fully performed, so a slimming health purpose is reached.
Description
Technical field
The invention belongs to the slimming health food technical field, being specifically related to a kind of is raw material with navy bean extract and L-arabinose, has the compound slimming health food of Weight-reducing health function.
Background technology
Along with The development in society and economy, the raising of people's living standard and the change of original eating habit, obesity has become the epidemic disease in the modern society; Other metabolic syndromes that bring by obesity; Diabetes, fatty liver, hyperlipemia; Hypertension, coronary heart disease is serious threat people healthy.Fat pathogenesis is very complicated, but for most overweight peoples, all underconsumption causes because caloric intake is too much, and bad eating habit is the common factor that causes body weight gain.Common method of weight-reducing has medicinal treatment, kinesiatrics, dietetic treatment at present; Wherein for the common bound drug therapy of adiposis patient; The comprehensive method of weight-reducing that dietetic treatment and kinesiatrics mutually combine, medicinal treatment can help those to use dietetic treatment and the inoperative obese patient of kinesiatrics to lose weight, therefore; Selection and exploitation have the slimming medicine and the functional food of remarkable fat-reducing effect and good safety, have extremely obvious practical significance for preventing and treating obesity.
Summary of the invention
The health food that the purpose of this invention is to provide a kind of integrated control obesity; Thereby aspect minimizing bodies such as the digestion of this health food sucrose and starch from suppress food and absorption play the purpose of fat-reducing to the absorption of energy, and the while can not influence the picked-up and the absorption of protein and vitamin.
The object of the invention is realized like this:
A kind of slimming health food, by weight, raw material comprises navy bean extract 4-20 part and L-arabinose 80-96 part.
Further, by weight, raw material comprises navy bean extract 4-20%, L-arabinose 80-96%.
In preferred embodiment of the present invention, described navy bean extract is the water extract of navy bean.The method that water extracts navy bean has multiple, in preferred embodiment of the present invention, can adopt following method: by navy bean and water by quality: volume=1: 4-8 poach 1-3 time, 1-5 hour at every turn, concentrated water cooking liquid, spray-drying and getting.
Slimming health food of the present invention can be processed the oral formulation of tablet or granule or other.Described carrier includes but not limited to filler, wetting agent, and said filler is starch, dextrin, lactose, sucrose, Icing Sugar, microcrystalline cellulose, glucose, meglumine, Glucosamine, sweet mellow wine, calcium sulfate or calcium bisulfate; Wetting agent is water or ethanol.
In preferred embodiment of the present invention, described preparation is a tablet, and said filler is sucrose or glucose, and described wetting agent is a water.
In preferred embodiment of the present invention, described preparation is an oral liquid, and described carrier includes but not limited to solvent, and described solvent is water or organic solvent, or the mixture of the different proportion of the organic solvent in water.
Because existing slimming medicine all has serious adverse, the applicant has researched and developed slimming health food safely and effectively, can reach the purpose of fat-reducing and does not damage body function.The L-arabinose can suppress the activity of invertase in the body, is digested and assimilated in alimentary canal thereby reduce sucrose, reduces the caloric intake in the food; The navy bean extract can suppress the activity of body endo-amylase, thereby reduces the digestion and the absorption of starch in the food, reduces the picked-up of energy.These two kinds of natural products all have the characteristics of the absorption of other nutriments such as not influencing protein and vitamin, through compound proportioning, its advantage on weight losing function are not fully exerted, and reach the purpose of Weight-reducing health.
The L-arabinose has good physiologically active and function, and in anti-fat nutritious supplementary pharmaceutical and non-prescribed medicine are listed the L-arabinose by U.S. food drug surveilance office (FDA); Japanese health ministry is listed it in special-purpose special food supplement and is used to regulate blood sugar; China Ministry of Public Health ratified the L-arabinose as new resource food in 2008.The physiological function of L-arabinose: (1) suppresses the metabolism and the absorption of sucrose, and control blood sugar raises: naturally occurring arabinose is the L-type, and it in animal body can not be by metabolism, but pleasantly sweet empty calory.In addition, it suppresses invertase in the enteron aisle with non-competing mode, thereby suppresses sucrose in enteral absorption.It is about 60% that the L-arabinose that in sucrose, adds 2-3% just can make sucrose reduce in the digestion of small intestine, makes blood sugar steady, the amount minimizing in blood of insulin and triglycerides; (2) suppressing fat generates: the L-arabinose hinders sucrose to be digested and assimilated, and the energy that body is obtained reduces, thereby the possibility that body weight is increased reduces, and helps controlling body weight.Therefore, it has very big benefit as a kind of sweetener and food additives, in order to fat-reducing and control blood sugar prevention diabetes.
Navy bean extract in the slimming health food of the present invention is extracted by navy bean (English name: White Kidney Bean P.E., latin name Phaseolus vulgaris. belongs to pulse family, Papillionoideae, Phaseoleae Phaseolus) and to form.Having the active main component of fat-reducing in the navy bean extract is alpha-amylase inhibitor; Alpha-amylase inhibitor (α-amytaseinhibitor; Abbreviate α-AI) as; Be a kind of natural bioactivator, belong to glycoside hydrolase inhibitor, be present in the metabolite of microorganism with the embryo of a plant seed breast in; Amylase to mammal ptyalin and amylopsin and the existence of insect alimentary canal has special inhibition activity, is called as " starch blocking-up person " (starehblocker).It is the activity through inhibition ptyalin and pancreatic, hinders starch and the digestion of other carbohydrate in enteron aisle in the food, thereby reduces picked-up and the absorption of body to sugar; Be characterized in not influencing protein; Other absorption of nutrient ingredients such as vitamin and metabolism reduce blood-sugar content, reduce the synthetic of fat; Play the effect of hypoglycemic, prevention of obesity and fat-reducing, be used for control clinically diseases such as diabetes, hyperglycaemia, highs fat of blood.The present invention's water from natural beans extracts alpha-amylase inhibitor, does not have dissolvent residual, and is healthy and safe.
The present invention carries out compound proportioning with navy bean extract and L-arabinose; The digestion that suppresses starch in the food through the navy bean extract combines the L-arabinose to suppress the digestion and the absorption of sucrose in the food with absorption; Both synergies; The common promotion obtains excess energy thereby better reduce body from food, reach the purpose of Weight-reducing and lipid-lowering.
The present invention combines the composition of different effects principle cleverly, and they are acted synergistically by different way, and then reaches the effect of Weight-reducing health.The L-arabinose can suppress the effect of invertase in the alimentary canal on the one hand, thereby reduction sucrose is decomposed in alimentary canal and absorbs, and has reduced the absorption of sucrose in the food.The main active alpha-amylase inhibitor of navy bean extract can suppress the effect that starch and other carbohydrate are decomposed into glucose absorption on the other hand; The two compound proportioning can be given full play to enzyme inhibitor advantage separately; Thereby play the absorption that reduces excess energy; Prevent that excessive power from transforming into fat, play better Weight-reducing and lipid-lowering effect.
The present invention and existing compared with techniques have following advantage:
1, slimming health food of the present invention is safe and effective, and mechanism is clear and definite, and fat-reducing effect is obvious.
2, slimming health food of the present invention not only can lose weight, and reduces body fat and hoards, and reduces the effect of blood fat, blood sugar in addition.
3, slimming health food of the present invention does not influence the digestion and the absorption of protein and vitamin, and is healthy and safe.
4, slimming health food of the present invention, preparation method's technology is simple, and is easy to operate.
The specific embodiment
Embodiment one
Raw material: raw material: the L-arabinose, purity 99%, passing biotechnology (Xiamen) Co., Ltd by Tang provides
Produce the navy bean extract: by navy bean and water by quality: volume=1: 4-8 poach 1-3 time, each 1-5 hour, concentrated water cooking liquid, spray-drying and getting.
Embodiment two
Raw material: L-arabinose, purity 99%.
The navy bean extract: by navy bean and water by quality: volume=1: 6 poach 2 times each 2 hours, concentrates water cooking liquid, spray-drying and get yield 20%.
SPF level male SD rat is adopted in experiment, and body weight 100-120g is divided into the normal control group at random, gives normal diet and feeds; Fat modeling group gives the high glucose and high fat forage feed.High lipid food prescription: basal feed 55%, casein 20%, sucrose 10%, lard 13%, salt 1%, dusty yeast 1%.Freely drink water, take food.Feed after 60 days; (modeling group rat body weight-normal rat body weight)/normal rats body weight * 100%＞20% is judged as the successful obese rat of modeling, is divided into sugar group in model control group, kidney bean low sugar group, the kidney bean, the high sugar group of kidney bean, positive controls (sibutramine hydrochloride) at random by body weight; Give kidney bean low sugar group with irritating stomach mode every morning: 300mg/kg.d navy bean extract+1.5g/kg.d L-arabinose; Sugar group in the kidney bean: 300mg/kg.d navy bean extract+3.0g/kg.d L-arabinose, the high sugar group of kidney bean: 300mg/kg.d navy bean extract+6.0g/kg.d L-arabinose, positive controls: 4mg/kg.d sibutramine hydrochloride; Normal control group and fat model control group give equivalent distilled water respectively; Every group 10, carry out the animal weight-reducing experiment, tested 80 days by a definite date.
be BW wherein: rat body weight (g), BL: the length of rat nose to anus (cm); Fat coefficient=fatty weight in wet base (g)/body weight (g) * 100%; Liver index=liver wet weights (g)/body weight (g) * 100%.Experimental result shows:
1. product of the present invention can effectively reduce the obese rat body weight, administration 20,40,60,80 days, and high sugared group rat of sugared group and kidney bean and model control group compare in kidney bean low sugar group, the kidney bean, and body weight all obviously reduces, all difference remarkable (P＜0.01).The result sees table 1.
The table 1 different dosing stage is to influence (g) n=10 of rat body weight
Annotate: with compared with normal,
*P＜0.05,
*P＜0.01; Compare with model group,
△P＜0.05,
△ △P＜0.01.
2. product of the present invention can effectively reduce the obese rat serum triglyceride; Administration 20,40,60,80 days; Sugared group and the high sugared group rat of kidney bean and fat model control group compare in kidney bean low sugar group, the kidney bean, and serum triglyceride all obviously reduces, all difference remarkable (P＜0.05 or P＜0.01).The result sees table 2.
The table 2 different dosing stage is to influence (mmol/L) n=10 of rat blood serum triglycerides
Annotate: with compared with normal,
*P＜0.05,
*P＜0.01; Compare with model group,
△P＜0.05,
△ △P＜0.01.
3. product of the present invention can effectively reduce obese rat serum low-density LP cholesterol; Administration 20,40,60,80 days; High sugar group rat of sugar group and kidney bean and fat model control group are relatively in kidney bean low sugar group, the kidney bean; The serum low-density LP cholesterol all obviously reduces, all difference remarkable (P＜0.05 or P＜0.01).The result sees table 3.
The table 3 different dosing stage is to influence (mmol/L) n=10 of rat blood serum LDL-C
Annotate: with compared with normal,
*P＜0.05,
*P＜0.01; Compare with model group,
△P＜0.05,
△ △P＜0.01.
4. product of the present invention can effectively reduce obese rat serum blood sugar; Administration 20,40,60,80 days; Sugared group and the high sugared group rat of kidney bean and fat model control group compare in kidney bean low sugar group, the kidney bean, and serum blood sugar all obviously reduces, all difference remarkable (P＜0.05 or P＜0.01).The result sees table 4.
The table 4 different dosing stage is to influence (mmol/L) n=10 of the serum blood sugar of rat
Annotate: with compared with normal,
*P＜0.05,
*P＜0.01; Compare with model group,
△P＜0.05,
△ △P＜0.01.
5. product of the present invention can effectively reduce obese rat Lee ' s index, fatty weight in wet base, fat coefficient; Administration 80 days; High sugar group rat of sugar group and kidney bean and fat model control group are relatively in kidney bean low sugar group, the kidney bean; Lee ' s index, fatty weight in wet base, fatty series number average obviously reduce, all difference remarkable (P＜0.05 or P＜0.01).The result sees table 5.
Table 5 administration 80 days is to the n=10 that influences of rat Lee ' s index, fatty weight in wet base, fat coefficient, liver index
Annotate: with compared with normal,
*P＜0.05,
*P＜0.01; Compare with model group,
△P＜0.05,
△ △P＜0.01.
Above-mentionedly be merely specific embodiment of the present invention, but design concept of the present invention is not limited thereto, allly utilizes this design that the present invention is carried out the change of unsubstantiality, all should belong to the behavior of invading protection domain of the present invention.
Claims (7)
1. a slimming health food is characterized in that, by weight, raw material comprises navy bean extract 4-20 part and L-arabinose 80-96 part.
2. slimming health food according to claim 1 is characterized in that: by weight, raw material comprises navy bean extract 4-20% and L-arabinose 80-96%.
3. slimming health food according to claim 1 and 2 is characterized in that: described navy bean extract is the water extract of navy bean.
4. slimming health food according to claim 3 is characterized in that: described navy bean extract is obtained by following method: by navy bean and water by quality: volume=1: 4-8 poach 1-3 time, each 1-5 hour, concentrated water cooking liquid, spray-drying and getting.
5. slimming health food according to claim 1; It is characterized in that: this slimming health food is tablet or granule; Described carrier includes but not limited to filler, wetting agent, and said filler is starch, dextrin, lactose, sucrose, Icing Sugar, microcrystalline cellulose, glucose, meglumine, Glucosamine, sweet mellow wine, calcium sulfate or calcium bisulfate; Wetting agent is water or ethanol.
6. slimming health food according to claim 5 is characterized in that, described slimming health food is a tablet, and said filler is sucrose or glucose, and described wetting agent is a water.
7. according to the slimming health food described in the claim 1, it is characterized in that: described preparation is an oral liquid, and described carrier includes but not limited to solvent, and described solvent is water or organic solvent, or the mixture of the different proportion of the organic solvent in water.
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| CN103230021A (en) * | 2012-08-10 | 2013-08-07 | 广州市赛健生物科技有限公司 | Weight-loss health-care food and preparation method thereof |
| CN103250950A (en) * | 2013-05-31 | 2013-08-21 | 广东九天绿药业有限公司 | Full-nutritional food combination and preparation method thereof |
| CN103945835A (en) * | 2011-11-01 | 2014-07-23 | 吕健民 | A composition and method of delivery of l-arabinose and select compounds |
| CN105614800A (en) * | 2015-12-22 | 2016-06-01 | 陕西今正蜂业有限公司 | Eucommia ulmoides male flower honey and preparation technology thereof |
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| CN105707887A (en) * | 2016-03-03 | 2016-06-29 | 山东禹王制药有限公司 | Health care and weight loss chewable tablet and preparation method thereof |
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| CN107319342A (en) * | 2017-08-08 | 2017-11-07 | 合肥康桥工贸有限公司 | The sugared rice of one kind control |
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| CN107373319A (en) * | 2017-08-08 | 2017-11-24 | 合肥康桥工贸有限公司 | One kind controls sugared cereal and reconstitutes instant product |
| CN107372729A (en) * | 2017-08-08 | 2017-11-24 | 合肥康桥工贸有限公司 | One kind controls sugared cake |
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Application publication date: 20120307 |