CN102362900B - Traditional Chinese medicine perfusate used for treating dairy cow mastitis caused by pathogenic bacteria - Google Patents
Traditional Chinese medicine perfusate used for treating dairy cow mastitis caused by pathogenic bacteria Download PDFInfo
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- CN102362900B CN102362900B CN 201110231671 CN201110231671A CN102362900B CN 102362900 B CN102362900 B CN 102362900B CN 201110231671 CN201110231671 CN 201110231671 CN 201110231671 A CN201110231671 A CN 201110231671A CN 102362900 B CN102362900 B CN 102362900B
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- 239000003814 drug Substances 0.000 title claims abstract description 24
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- 239000007788 liquid Substances 0.000 claims description 12
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine perfusate used for treating dairy cow mammitis caused by pathogenic bacteria. The traditional Chinese medicine perfusate is composed of Chinese herbal medicines of dandelion, angelica archang lica, mongolian snakegourd fruit, chinese goldthread rhizome, and weeping forsythia fruit. Clinical applications and laboratory researches chow that, with the formula provided by the invention, pathogenic bacteria in breasts can be thoroughly killed, and milk production performance can be rapidly recovered, wherein a recovery rate reaches 83.3%. The traditional Chinese medicine perfusate is suitable for industrialized batch productions.
Description
[technical field]
The present invention relates to veterinary Chinese medicine, relate in particular to a kind of Chinese medicinal perfusion liquid for the treatment of milch cow pathogen property mastitis.
[background technology]
Mastitis is a kind of disease of the most common in world's dairy and economic loss maximum, and its pathogenic factor mainly is cause pathogeny imcrobe infection.The pathogenic microorganism that causes mammitis of cow is very complicated, comprise the kinds more than 130 such as antibacterial, fungus, virus, mycoplasma, wherein take the antibacterial infection as main (such as staphylococcus aureus, escherichia coli, streptococcus agalactiae, streptococcus dysgalactiae), next is fungal infection (such as Candida albicans and Candida tropicalis), and usually is the mixed infection of antibacterial fungus.The generation of this disease directly affects output and the quality of milk on the one hand, also can reduce on the other hand the service life of milch cow, increases mortality.Sickness rate is high clinically, control is difficult for this disease, is listed in one of milch cow four large diseases.
The at present prophylactico-therapeutic measures of mammitis of cow is a lot, such as anti-inflammation, enhancing body resistance, and be aided with corresponding vaccine immunity and good feeding and management etc., but effect is unsatisfactory.Western medicine mastitis such as the clinical antibiotic that generally adopts and chemical synthetic drug particularly, on the one hand, western medicine composition is single, and antimicrobial spectrum is limited, does not satisfy multiple pathogen mixed infection; On the other hand, the drug resistance phenomenon ubiquity that Western medicine is antibiotic, although dosage strengthens again and again, clinical efficacy is not good; In addition antibiotic residue problem, directly harm humans is healthy.
[summary of the invention]
The technical problem to be solved in the present invention provides and a kind ofly is used for the treatment of milch cow pathogen property mastitis and produce effects is fast, toxicity is low, easily metabolism, not residual Chinese medicinal perfusion liquid.
In order to solve the problems of the technologies described above, the technical solution used in the present invention is, a kind of Chinese medicinal perfusion liquid that is used for the treatment of milch cow pathogen property mastitis, and described Chinese medicinal perfusion liquid is comprised of following Chinese medicine: Herba Taraxaci, the Radix Angelicae Dahuricae, Fructus Trichosanthis, Rhizoma Coptidis, Fructus Forsythiae.
As preferably, described Chinese medicinal perfusion liquid is comprised of the Chinese medicine of following weight portion: Herba Taraxaci 3-7 part, Radix Angelicae Dahuricae 1-4 part, Fructus Trichosanthis 2-5 part, Rhizoma Coptidis 2-5 part, Fructus Forsythiae 2-5 part.
As preferably, described Chinese medicinal perfusion liquid is comprised of the Chinese medicine of following weight portion: 4 parts of Herba Taraxacis, 2 parts of the Radixs Angelicae Dahuricae, 3 parts of Fructus Trichosanthis, 4 parts of Rhizoma Coptidis, 2 parts of Fructus Forsythiaes.
According to herbal pharmacology, the furuncle carbuncle toxin is controlled in Herba Taraxaci, Fructus Forsythiae heat-clearing and toxic substances removing, removing heat from blood detumescence, more controls the common medicine of acute mastitis; Radix Angelicae Dahuricae wind-damp dispelling, the evacuation of pus of invigorating blood circulation, granulation promoting pain relieving, the available ulcer sores of controlling; Fructus Trichosanthis clearing away phlegm knot, subduing inflammation, heat clearing away eliminating stagnation, control acute mastitis from the beginning of; The Rhizoma Coptidis heat clearing and damp drying, detoxifcation doctor skin ulcer, available carbuncle furuncle, the pathopyretic ulcer controlled.Modern pharmacological research shows that Herba Taraxaci, the Radix Angelicae Dahuricae, Fructus Trichosanthis, Rhizoma Coptidis, Fructus Forsythiae all have stronger inhibitory or killing effect to the encountered pathogenic bacteria (antibacterial and fungus) that causes mastitis, and the Radix Angelicae Dahuricae, Rhizoma Coptidis and Fructus Forsythiae also have obvious antiinflammatory action.
The invention has the beneficial effects as follows:
The present invention is pure Chinese medicinal preparation, action target spot is many, to infecting the pathogenetic bacteria and the fungus that are separated in the breast obvious curative effect is arranged, and the difficult drug resistance that produces, toxicity is low, easily metabolism, not residual, thereby to this many cause of diseases of class disease of mammitis of cow, significant to solving milk product drug residue and pathogenic bacteria resistance to drugs problem.Adopt in addition the dosage form of infusion liquid, medicine directly contacts with mammary gland tissue, can kill face-to-face and infect intramammary pathogen, and produce effects is rapid.Clinical practice shows that this prescription can thoroughly be killed the pathogen in the breast, recovers to give milk rapidly function, and cure rate is up to 83.3%, is suitable for industrialized mass production.
[specific embodiment]
Embodiment 1
1, formula components (weight portion): 3 parts of Herba Taraxacis, 1 part of the Radix Angelicae Dahuricae, 2 parts of Fructus Trichosanthis, 2 parts of Rhizoma Coptidis, 2 parts of Fructus Forsythiaes, above-mentioned medical material is the prepared slices of Chinese crude drugs.
2, preparation method:
(1) the preliminary pulverizing: get it filled by above-mentioned formula proportion and weigh, be ground into first coarse powder, mixing.
(2) ethanol extraction: the said medicine coarse powder is placed extraction pot, add 80% alcohol reflux 2h, filter.
(3) ultrasonic cell disrupte extracts: get the medicinal residues behind the ethanol extraction, put into the ultrasonic cell disrupte extraction pot, adding distil water, supersound extraction 30min.Ultrasonic complete after, filter, the filtering residue reprocessing once.Merge 2 times filtrate.
(4) concentrated: all filtrates of above-mentioned ethanol extraction and supersound extraction are merged, wave most ethanol, the 12000r/m high speed centrifugation is got supernatant, and Rotary Evaporators is concentrated into 0.1g/mL.Add again 0.8mL Tween 80 and 10mL PEG400, mixing in every 100mL concentrated solution.Aseptic subpackaged by every bottle of 10mL, autoclaving, 4 ℃ of cold preservations are for subsequent use.
3, Therapeutic Method: before use, every 10mL medicinal liquid adds the 30mL distilled water diluting, and perfusion in the breast according to 20 milliliters in each breast district, once a day, is used in conjunction 5 days.
4, curative effect statistics: 30 milch cows that suffer from mastitis in certain cattle farm are treated, and medication every day is once cured 22 after being used in conjunction five days, and cure rate reaches 73.3%.
Embodiment 2
1, formula components (weight portion): 4 parts of Herba Taraxacis, 2 parts of the Radixs Angelicae Dahuricae, 3 parts of Fructus Trichosanthis, 4 parts of Rhizoma Coptidis, 2 parts of Fructus Forsythiaes, above-mentioned medical material is the prepared slices of Chinese crude drugs.
2, preparation method and Therapeutic Method: with embodiment 1.
3, curative effect statistics: 48 milch cows that suffer from mastitis in certain cattle farm are treated, and medication every day is once cured 40 after being used in conjunction five days, and cure rate reaches 83.3%.
Embodiment 3
1, formula components (weight portion): 7 parts of Herba Taraxacis, 4 parts of the Radixs Angelicae Dahuricae, 5 parts of Fructus Trichosanthis, 5 parts of Rhizoma Coptidis, 5 parts of Fructus Forsythiaes, above-mentioned medical material is the prepared slices of Chinese crude drugs.
2, preparation method and Therapeutic Method: with embodiment 1.
3, curative effect statistics: 36 milch cows that suffer from mastitis in certain cattle farm are treated, and medication every day is once cured 28 after being used in conjunction five days, and cure rate reaches 77.8%.
Claims (2)
1. a Chinese medicinal perfusion liquid that is used for the treatment of milch cow pathogen property mastitis is characterized in that, described Chinese medicinal perfusion liquid is comprised of the Chinese medicine of following weight portion: Herba Taraxaci 3-7 part, Radix Angelicae Dahuricae 1-4 part, Fructus Trichosanthis 2-5 part, Rhizoma Coptidis 2-5 part, Fructus Forsythiae 2-5 part.
2. the described Chinese medicinal perfusion liquid that is used for the treatment of milch cow pathogen property mastitis according to claim 1 is characterized in that described Chinese medicinal perfusion liquid is comprised of the Chinese medicine of following weight portion: 4 parts of Herba Taraxacis, 2 parts of the Radixs Angelicae Dahuricae, 3 parts of Fructus Trichosanthis, 4 parts of Rhizoma Coptidis, 2 parts of Fructus Forsythiaes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110231671 CN102362900B (en) | 2011-08-12 | 2011-08-12 | Traditional Chinese medicine perfusate used for treating dairy cow mastitis caused by pathogenic bacteria |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110231671 CN102362900B (en) | 2011-08-12 | 2011-08-12 | Traditional Chinese medicine perfusate used for treating dairy cow mastitis caused by pathogenic bacteria |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102362900A CN102362900A (en) | 2012-02-29 |
| CN102362900B true CN102362900B (en) | 2013-03-13 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 201110231671 Expired - Fee Related CN102362900B (en) | 2011-08-12 | 2011-08-12 | Traditional Chinese medicine perfusate used for treating dairy cow mastitis caused by pathogenic bacteria |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102362900B (en) |
-
2011
- 2011-08-12 CN CN 201110231671 patent/CN102362900B/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
|---|
| 杨玉凤，等.中药方剂防治各类奶牛乳房炎.《农村养殖科技》.2007,(第14期),第25页. * |
| 王雄清,等.10种中药对奶牛乳房炎病原菌的体外抑菌试验.《绵阳师范学院学报》.2006,第25卷(第2期),第52-55页. * |
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| CN102362900A (en) | 2012-02-29 |
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