CN1246001C - 'Fufukang' Chinese traditional medicine preparation and preparing process thereof - Google Patents
'Fufukang' Chinese traditional medicine preparation and preparing process thereof Download PDFInfo
- Publication number
- CN1246001C CN1246001C CN 200410021839 CN200410021839A CN1246001C CN 1246001 C CN1246001 C CN 1246001C CN 200410021839 CN200410021839 CN 200410021839 CN 200410021839 A CN200410021839 A CN 200410021839A CN 1246001 C CN1246001 C CN 1246001C
- Authority
- CN
- China
- Prior art keywords
- preparation
- time
- medicine preparation
- chinese medicine
- prepared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 36
- 239000003814 drug Substances 0.000 title claims abstract description 20
- 238000000034 method Methods 0.000 title abstract description 5
- 210000001215 vagina Anatomy 0.000 claims abstract description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 16
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 12
- 239000000706 filtrate Substances 0.000 claims description 12
- 239000012567 medical material Substances 0.000 claims description 12
- 201000010099 disease Diseases 0.000 claims description 11
- 239000000796 flavoring agent Substances 0.000 claims description 11
- 235000019634 flavors Nutrition 0.000 claims description 11
- 239000007921 spray Substances 0.000 claims description 7
- 208000013464 vaginal disease Diseases 0.000 claims description 7
- -1 effervescent Substances 0.000 claims description 6
- 229920001214 Polysorbate 60 Polymers 0.000 claims description 5
- 239000006210 lotion Substances 0.000 claims description 5
- 239000012528 membrane Substances 0.000 claims description 5
- 238000004064 recycling Methods 0.000 claims description 5
- 238000003756 stirring Methods 0.000 claims description 5
- 239000000443 aerosol Substances 0.000 claims description 4
- 239000002775 capsule Substances 0.000 claims description 4
- 239000000284 extract Substances 0.000 claims description 4
- 239000007937 lozenge Substances 0.000 claims description 4
- 229940023488 pill Drugs 0.000 claims description 4
- 239000006187 pill Substances 0.000 claims description 4
- 239000007901 soft capsule Substances 0.000 claims description 4
- 239000000829 suppository Substances 0.000 claims description 4
- 229940098465 tincture Drugs 0.000 claims description 4
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 3
- 229930006000 Sucrose Natural products 0.000 claims description 3
- 238000012869 ethanol precipitation Methods 0.000 claims description 3
- 239000005720 sucrose Substances 0.000 claims description 3
- 238000005303 weighing Methods 0.000 claims description 3
- 239000006196 drop Substances 0.000 claims description 2
- 238000000605 extraction Methods 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 239000007935 oral tablet Substances 0.000 claims description 2
- 229940096978 oral tablet Drugs 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 17
- 208000003251 Pruritus Diseases 0.000 abstract description 16
- 230000036407 pain Effects 0.000 abstract description 9
- 206010046914 Vaginal infection Diseases 0.000 abstract description 7
- 230000017531 blood circulation Effects 0.000 abstract description 7
- 230000001737 promoting effect Effects 0.000 abstract description 7
- 230000007803 itching Effects 0.000 abstract description 6
- 208000002003 vulvitis Diseases 0.000 abstract description 5
- 206010047799 Vulvovaginitis trichomonal Diseases 0.000 abstract description 4
- 241000588724 Escherichia coli Species 0.000 abstract description 2
- 241000588652 Neisseria gonorrhoeae Species 0.000 abstract description 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 abstract description 2
- 241000191967 Staphylococcus aureus Species 0.000 abstract description 2
- 241000191963 Staphylococcus epidermidis Species 0.000 abstract description 2
- 241000194017 Streptococcus Species 0.000 abstract description 2
- 230000002949 hemolytic effect Effects 0.000 abstract description 2
- 230000003285 pharmacodynamic effect Effects 0.000 abstract description 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 201000007336 Cryptococcosis Diseases 0.000 abstract 1
- 241000221204 Cryptococcus neoformans Species 0.000 abstract 1
- 241000238631 Hexapoda Species 0.000 abstract 1
- 241001363490 Monilia Species 0.000 abstract 1
- 240000003705 Senecio vulgaris Species 0.000 abstract 1
- 241000223229 Trichophyton rubrum Species 0.000 abstract 1
- 201000008100 Vaginitis Diseases 0.000 abstract 1
- 230000036592 analgesia Effects 0.000 abstract 1
- 230000009194 climbing Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 231100000614 poison Toxicity 0.000 description 9
- 239000003440 toxic substance Substances 0.000 description 8
- 239000000047 product Substances 0.000 description 6
- 208000004926 Bacterial Vaginosis Diseases 0.000 description 4
- 229940124579 cold medicine Drugs 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 201000004624 Dermatitis Diseases 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 244000045947 parasite Species 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000000749 insecticidal effect Effects 0.000 description 2
- 239000008921 jie er yin Substances 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 206010003693 Atrophic vulvovaginitis Diseases 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 241000754688 Cercaria Species 0.000 description 1
- 241000242722 Cestoda Species 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 208000003322 Coinfection Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010010726 Conjunctival oedema Diseases 0.000 description 1
- 241001337994 Cryptococcus <scale insect> Species 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000201295 Euphrasia Species 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 208000015817 Infant Nutrition disease Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 241000242678 Schistosoma Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 240000004460 Tanacetum coccineum Species 0.000 description 1
- 208000007074 Trichomonas Vaginitis Diseases 0.000 description 1
- 208000025206 Trichomonas vaginitis urogenital infection Diseases 0.000 description 1
- 241000223238 Trichophyton Species 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 230000001572 anti-trichomonad Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 230000002607 hemopoietic effect Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002687 intercalation Effects 0.000 description 1
- 238000009830 intercalation Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229940071462 oralone Drugs 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 201000010808 postmenopausal atrophic vaginitis Diseases 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention relates to a 'Fufukang' Chinese traditional medicine preparation and a preparing process thereof, and the preparation is mainly prepared from creeping rostellularia herb and climbing groundsel; compared with the prior art, the present invention has effect on clearing away heat and toxic material, promoting blood circulation to stop pain and killing insects and relieving itching, and is used for treating colpitis mycotica, trichomonal vaginitis, bacteria vaginitis, vulvitis, pruritus of vagina, itch of skin, etc. The modern pharmacodynamics research proves that the present invention has good effect on phlogosis resistance, relieving itching and analgesia; a bacteriostasis experiment proves that the present invention has obvious bacteriostasis and sterilization effect on treating staphylococcus aureus, beta hemolytic streptococcus, pseudomonas aeruginosa, trichophyton rubrum, staphylococcus epidermidis, escherichia coli, neisseria gonorrhoeae, monilia albicans, novel cryptococcus neoformans, acrothesium floccosum, etc.
Description
Technical field: the present invention relates to a kind of Chinese medicine preparation for the treatment of the female vagina disease and preparation method thereof, belong to the field of traditional Chinese medicine technology.
Technical background: symptoms such as married woman's vaginal infection inflammation and pudendal pruritus, skin pruritus are commonly encountered diseases, frequently-occurring disease, often upset that the patient works normally, studying and living; Serious needs of patients is treated in hospital; Existing medicine has that JIEERYIN XIYE, woman's inflammation are clean, the scorching cream of woman or the like, and these medicines have certain therapeutical effect, but have certain problem: the one, and DeGrain, treatment time is long, or some curative effects are arranged, but curative effect is impermanent; The 2nd, their medicine constitutes more complicated, and the medical material that uses in the preparation process is too much, makes quality be difficult to be controlled better; Such present situation is difficult to satisfy demands of social development.
Summary of the invention: the objective of the invention is to: carry out deep development on square basis, a kind of Chinese medicine preparation for the treatment of the female vagina disease and preparation method thereof is provided at Guizhou Miao ethnic group regional experience; The present invention constitutes like this: calculate according to composition by weight: it is mainly by Herba Rostellulariae 80-180, and Herba Senecionis Scandentis 80-180 is prepared from specifically: it is by Herba Rostellulariae 120g, and Herba Senecionis Scandentis 80g is prepared from.Described preparation is a spray.Described preparation can also be: lotion, suppository, membrane, effervescent, tincture, lozenge, aerosol or oral tablet, capsule, soft capsule, granule, drop pill.Preparation method is: according to given ratio, medical material is made clear paste with ethanol precipitation after decocting in water extracts, be prepared into needed preparation then or medical material is got clear paste, is prepared into needed preparation then through alcohol extraction.Concrete method: get Herba Rostellulariae, after Herba Senecionis Scandentis two flavor medical materials add water retting 4-6 hour, decoct 3 times, 2 hours for the first time, 1.5 hours for the second time, 1 hour for the third time, gradation is filtered, and merging filtrate also is concentrated into relative density and surveys in the time of 70-80 ℃ and be the clear paste of 1.13-1.15, then, can suppress in flakes, fill becomes capsule, soft capsule, perhaps add sucrose and be prepared into granular preparation or drop pill.The preparation spray preparing process is: take by weighing Herba Rostellulariae 120g, Herba Senecionis Scandentis 80g, after adding water retting 4-6 hour, decoct 3 times 2 hours for the first time, 1.5 hours for the second time, 1 hour for the third time, gradation was filtered, and merging filtrate also is concentrated into relative density and surveys in the time of 70-80 ℃ and be the clear paste of 1.13-1.15, put cold, add ethanol and make and contain the alcohol amount and reach 90%, left standstill 24 hours, filter, filtrate recycling ethanol is to there not being the alcohol flavor, add polyoxyethylene sorbitan monoleate 20g, add water to ormal weight again, stir evenly, filter, fill promptly gets the 1000ml external preparation, can further be prepared into spray, lotion, suppository, membrane, effervescent, aerosol, tincture, lozenge.
Compared with prior art: the present invention has heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, the worm itching relieving effect of stopping; Be used for treatment of conditions such as colpitis mycotica, trichomonal vaginitis, bacterial vaginitis, vulvitis and pruritus of vagina, skin pruritus; This product proves that through modern pharmacodynamic study antiinflammatory action is preferably arranged, itching-relieving action and analgesic activity.Prove through bacteriostatic test, this product is to staphylococcus aureus, beta hemolytic streptococcus, bacillus pyocyaneus, trichophyton, staphylococcus epidermidis, escherichia coli, Diplococcus gonorrhoeae, Candida albicans, Cryptococcus histolyticus, acrothesium floccosum etc. have significantly bacteriostasis or bactericidal action; Also have the anti-hook larva of a tapeworm or the cercaria of a schistosome and uncinarial dermatitis simultaneously, and the effect of anti-trichomonal.The side separates:
According to theoretical the returning of Miao ethnic group medicine through theory, medicine and disease are divided into cold and hot, the medicine of a warm nature is controlled cold disease, Gui Lengjing, cold medicine heats disease, returns hot warp.Married woman's vaginal infection disease, many genus infect unclean things, and long-pending for a long time how living damp and hot, damp and hot strongly fragrant in blood system, hemopoietic heat then further causes secondary infection again.Herba Rostellulariae in the prescription is the dry herb of acanthaceous plant Herba Rostellulariae.Be Guizhou Seedling doctor medical herbs commonly used, belong to cold medicine, has the disappear effect of stagnant, promoting blood circulation and stopping pain, Anti-Puritic and insecticidal of heat-clearing and toxic substances removing, dampness removing, it is intercalation to be usually used in cold, fever, laryngopharynx swelling and pain, infantile malnutrition etc., also be usually used in dermatitis, tinea pedis that the excrement poison causes, or pudendal pruritus due to unclean of vagina, erosion etc., but not only oral administration but also external.Herba Senecionis Scandentis is the dry aerial parts of feverfew Herba Senecionis Scandentis in the side, also is Seedling doctor conventional crude drugs.Belong to cold medicine, heat-clearing and toxic substances removing is arranged, the effect of eyesight-improving and pain-alleviating.Be usually used in anemopyretic cold, conjunctival congestion and swelling pain, dysentery, skin eczema, furuncle etc.This product is all gone into hot warp with the cold medicine phase 5 of two flavors, has then strengthened the merit of heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, killing parasites for relieving itching.Be applicable to colpitis mycotica, trichomonal vaginitis, bacterial vaginitis, vulvitis and skin pruritus etc.According to the theory of Chinese medical science analysis, this product is with heat-clearing and toxic substances removing, and dampness removing disappears stagnant, and the Herba Rostellulariae of promoting blood circulation and stopping pain, Anti-Puritic and insecticidal is monarch, is equipped with heat-clearing and toxic substances removing, makes eye bright, antipruritic Herba Senecionis Scandentis is minister, and both are 5 merits of playing heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, killing parasites for relieving itching altogether mutually.Infect so can be applicable to married woman's pudendum, due to inflammation and all diseases of pruritus.
The specific embodiment:
Embodiments of the invention 1: take by weighing Herba Rostellulariae 120g, Herba Senecionis Scandentis 80g, after adding water retting 4-6 hour, decoct 3 times, 2 hours for the first time, 1.5 hours for the second time, 1 hour for the third time, gradation is filtered, and merging filtrate also is concentrated into relative density and surveys in the time of 70-80 ℃ and be the clear paste of 1.13-1.15, puts cold, adding ethanol makes and contains the alcohol amount and reach 90%, left standstill 24 hours, and filtered, filtrate recycling ethanol is to there not being the alcohol flavor, add polyoxyethylene sorbitan monoleate 20g, add water to ormal weight again, stir evenly, filter, fill promptly gets the 1000ml spray.The product trade name of present embodiment production is: " Fufukang spray ".Be sprayed directly on to the patient affected part during use.
Embodiments of the invention 2: according to given ratio, with medical material Herba Rostellulariae 80kg, Herba Senecionis Scandentis 80kg makes clear paste with ethanol precipitation after decocting in water extracts, and then, adds the starch compacting in flakes.During use three times on the oral one, each two.
Embodiments of the invention 3: get Herba Rostellulariae 180g, Herba Senecionis Scandentis 180g added water retting after 4 hours, decocted three times, 2 hours for the first time, 1.5 hours for the second time, 1 hour for the third time, gradation is filtered, and merging filtrate also is concentrated into relative density and surveys in the time of 70-80 ℃ and be the clear paste of 1.13-1.15, then, put coldly, add ethanol and make and contain the alcohol amount and reach 90%, left standstill 24 hours, filter, filtrate recycling ethanol adds polyoxyethylene sorbitan monoleate 20g to there not being the alcohol flavor, add water to ormal weight again, stir evenly, filter, further be prepared into lotion.
Embodiments of the invention 4: it is by Herba Rostellulariae 150g, and Herba Senecionis Scandentis 150g is prepared from.Medical material is made clear paste after decocting in water extracts, add sucrose then and be prepared into granular preparation.Embodiments of the invention 5: it is by Herba Rostellulariae 100g, and Herba Senecionis Scandentis 80g is prepared from.Get Herba Rostellulariae, Herba Senecionis Scandentis two flavor medical materials added water retting after 6 hours, decoct 3 times, 2 hours for the first time, 1.5 hours for the second time, 1 hour for the third time, gradation is filtered, merging filtrate also is concentrated into relative density and surveys in the time of 70-80 ℃ and be the clear paste of 1.13-1.15, then, adds ethanol and makes and contain the alcohol amount and reach 90%, left standstill 24 hours, filter, filtrate recycling ethanol adds polyoxyethylene sorbitan monoleate 20g to there not being the alcohol flavor, add water to ormal weight again, stir evenly, filter, fill promptly gets the 1000ml external preparation, can further prepare membrane.In actual development process, the inventor finds: this prescription serves as basis side with Herba Rostellulariae, Herba Senecionis Scandentis, has heat-clearing and toxic substances removing if add the 1-2 flavor, blood circulation promoting and blood stasis dispelling, pain relieving, the prescription of the Chinese herbal medicine combination of killing parasites for relieving itching class; As add Herba Hedyotidis Diffusae, Radix Salviae Miltiorrhizae, Radix Zanthoxyli, Radix Angelicae Sinensis, Radix Sophorae Flavescentis, Fructus Cnidii, Herba Saxifragae, the Radix Stemonae, Rhizoma Curcumae, Cortex Phellodendri etc. have the treatment gynecological diseases medical material in simply or combination in any two the flavor medical materials all do not influence effect of the present invention and have certain auxiliary curative effect.
Clinical efficacy:
This product is through Guangzhou General Hospital Guangzhou Military Command's department of obstetrics and gynecology, gynecological of Guangzhou Medical College Annex II institute, gynecological of Guangdong Women and Children's Hospital and Health Insitute, three tame hospitals in October, 2000 to December, treatment vulvitis, nonspecific vaginitis, colpitis mycotica, trichomonal vaginitis, senile vaginitis, each 30 example is respectively established matched group 20 examples, with the JIEERYIN contrast, its result is:
Total is accepted 750 examples for medical treatment, and 450 examples are organized in treatment, clinical recovery example, produce effects 146 examples, effective 102 examples, invalid 41 examples, total effective rate are 90.9%, and are invalid 9.1%, and matched group is totally 300 examples, clinical recovery 69 examples, produce effects 78 examples, invalid 90 examples of effective 63 examples, total effective rate 70%, invalid 30%.
Through Ridit check, be criterion group with the matched group, R value=0.5, treatment group R value 0.629,95% is credible to be limited to 0.613～0.655, does not contain 0.5, and P＜0.05 then is so there were significant differences points out treatment group curative effect obviously to be better than matched group for treatment group and matched group comparison.See table 1 and table 2 for details.
Table 1 treatment group and matched group portion efficacy analysis
| Classification of diseases | Group | The example number | Recovery from illness | Produce effects | Effectively | Invalid | Total effective rate | The P value | |||||
| ％ | Example | ％ | Example | ％ | Example | ％ | Example | ％ | |||||
| Nonspecific vaginitis trichomonas vaginitis colpomycosis senile vahinitis vulvitis | Treatment group treatment of control group group treatment of control group group treatment of control group group treatment of control group group control group | 90 60 90 60 90 60 90 60 90 60 | 35 11 34 15 26 13 33 13 33 17 | 38.9 18.3 37.8 25 28.9 21.7 36.7 21.7 36.7 28.3 | 212 19 28 16 38 16 27 14 32 13 | 23.3 31.7 31.1 26.7 42.2 26.7 30 23.3 35.6 21.7 | 27 9 23 9 21 16 14 15 17 14 | 30 15 25.6 15 23.3 26.7 15.6 25 18.9 23.3 | 7 21 5 20 5 15 16 18 8 16 | 7.8 35 5.6 33.3 5.6 25 17.8 30 8.9 26.7 | 83 39 85 40 85 45 74 42 82 44 | 92.2 65.0 94.4 66.7 94.4 75.0 82.2 70.0 91.1 73.3 | ＜0.05 ＜0.05 ＜0.05 ＜0.05 ＜0.05 |
Table 2 treatment group and matched group total effects are relatively
| Group n | Example number (%) | |||||
| Recovery from illness | Produce effects | Effectively | Invalid | Cure rate | Total effective rate | |
| 450 161 matched groups 300 69 are organized in treatment | (35.77) (23.00) | 146 (32.44) 78 (26.00) | 102 (22.66) 63 (21.00) | 41 (9.12) 90 (30.00) | 207 (90.88) 147 (49.00) | 409 (90.88) 210 (70.00) |
| The Ridit check, R=0.629,95%cl:0.613～0.655 does not contain 0.5, P＜0.05. | ||||||
Claims (7)
1, a kind of Chinese medicine preparation for the treatment of the female vagina disease is characterized in that: according to listed as parts by weight: it is mainly by Herba Rostellulariae 80-180, and Herba Senecionis Scandentis 80-180 is prepared from.
2, according to the Chinese medicine preparation of the described treatment female vagina of claim 1 disease, it is characterized in that: it is by Herba Rostellulariae 120g, and Herba Senecionis Scandentis 80g is prepared from.
3, according to the Chinese medicine preparation of claim 1 or 2 described treatment female vagina diseases, it is characterized in that: described preparation is a spray.
4, according to the Chinese medicine preparation of claim 1 or 2 described treatment female vagina diseases, it is characterized in that: described preparation is: lotion, suppository, membrane, effervescent, aerosol, tincture, lozenge or oral tablet, capsule, soft capsule, granule, drop pill.
5, as the preparation method of the Chinese medicine preparation of right 1 or 2 described treatment female vagina diseases, it is characterized in that: according to given ratio, medical material is made clear paste with ethanol precipitation after decocting in water extracts, be prepared into needed preparation then or medical material is got clear paste, is prepared into needed preparation then through alcohol extraction.
6, according to the preparation method of the Chinese medicine preparation of the described treatment female vagina of claim 5 disease, it is characterized in that: above two the flavor medical materials, add water retting 4-6 hour after, decoct 3 times, 2 hours for the first time, 1.5 hours for the second time, 1 hour for the third time, gradation was filtered, merging filtrate also is concentrated into relative density and surveys in the time of 70-80 ℃ and be the clear paste of 1.13-1.15, then, compacting is in blocks, fill becomes capsule, soft capsule, perhaps adds sucrose and is prepared into granular preparation or drop pill.
7, preparation method according to the Chinese medicine preparation of the described treatment female vagina of claim 5 disease, it is characterized in that: take by weighing Herba Rostellulariae 120g, Herba Senecionis Scandentis 80g, after adding water retting 4-6 hour, decoct 3 times, 2 hours for the first time, 1.5 hours for the second time, 1 hour for the third time, gradation is filtered, merging filtrate also is concentrated into relative density and surveys in the time of 70-80 ℃ and be the clear paste of 1.13-1.15, puts coldly, adds ethanol and makes and contain the alcohol amount and reach 90%, left standstill 24 hours, filter, filtrate recycling ethanol adds polyoxyethylene sorbitan monoleate 20g to there not being the alcohol flavor, add water to ormal weight again, stir evenly, filter, fill promptly gets the 1000ml external preparation, is prepared into spray, lotion, suppository, membrane, effervescent, aerosol, tincture, lozenge.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410021839 CN1246001C (en) | 2004-02-13 | 2004-02-13 | 'Fufukang' Chinese traditional medicine preparation and preparing process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410021839 CN1246001C (en) | 2004-02-13 | 2004-02-13 | 'Fufukang' Chinese traditional medicine preparation and preparing process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1557443A CN1557443A (en) | 2004-12-29 |
| CN1246001C true CN1246001C (en) | 2006-03-22 |
Family
ID=34352066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410021839 Expired - Lifetime CN1246001C (en) | 2004-02-13 | 2004-02-13 | 'Fufukang' Chinese traditional medicine preparation and preparing process thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1246001C (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102008531B (en) * | 2010-12-06 | 2013-03-20 | 贵州荣发制药有限责任公司 | Fufukang gel and preparation method thereof |
| CN102743612B (en) * | 2012-06-17 | 2013-12-11 | 姚丽娟 | Preparation method of Chinese medicine irrigation solution for treating bean curd broken bits type mycotic vaginitis |
| CN103127312A (en) * | 2013-03-19 | 2013-06-05 | 迟仁智 | External Antiviral and anti-pathogenic gynecological lotion and preparation technology |
| CN105116081A (en) * | 2015-04-20 | 2015-12-02 | 贵阳德昌祥药业有限公司 | Detection method for heat-clearing and stasis-removing drugs |
| CN105362487A (en) * | 2015-12-12 | 2016-03-02 | 倪朝洪 | Traditional Chinese medicine composition for treating vaginitis |
-
2004
- 2004-02-13 CN CN 200410021839 patent/CN1246001C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CN1557443A (en) | 2004-12-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101195008B (en) | Cattail pollen skin cleaning agent for treating gynecology disease and technique of preparing the same thereof | |
| CN103110868B (en) | Skin care solution and preparation method thereof | |
| CN102139030B (en) | Oral Chinese herbal preparation for treating gingivitis and preparation method thereof | |
| CN102697961B (en) | Gynecological cleaning solution and preparation method thereof | |
| CN101337015B (en) | Traditional Chinese medicine for gynecology and dermatology and preparation method thereof | |
| CN101269192A (en) | Chinese medicinal composition for treating gynaecologic inflammation and preparation thereof | |
| CN103800772A (en) | Gynecological external lotion for preventing and treating vagina inflammatory diseases and preparation method thereof | |
| CN102488814B (en) | Chinese medicinal composition for treating bovine mastitis | |
| CN101129872A (en) | Phellodendron bark-coix seed erysipelas powder | |
| CN1246001C (en) | 'Fufukang' Chinese traditional medicine preparation and preparing process thereof | |
| CN103239676B (en) | Topical pharmaceutical composition for preventing and treating bacterial vaginosis | |
| CN101288754B (en) | Huyuebao preparation | |
| CN104666594A (en) | Moxibustion stick for treating tinea pedis and preparation method thereof | |
| CN101391065A (en) | Compound semen momordicae and pepper soup for treating acute and chronic pelvic inflammatory diseases | |
| CN1977894A (en) | Medicinal composition with anti-inflammation effect and its preparing method | |
| CN103751532A (en) | Traditional Chinese medicine composition for treating gynecological inflammation and preparation method thereof | |
| CN1330362C (en) | Wound dispelling swell dispersing tincture and its preparation method | |
| CN100402073C (en) | Medicine for treating disease caused by heat toxin | |
| CN102357147B (en) | Chinese medicine composite tincture capable of diminishing inflammation, relieving pain and preventing viruses and preparation method thereof | |
| CN105079305A (en) | Antisepsis and anti-inflammation external traditional Chinese medicine compound gel and preparation method thereof | |
| CN113521142A (en) | Pharmaceutical composition for treating seborrheic dermatitis, preparation method and application thereof, and head bath soaking agent and preparation method thereof | |
| CN103157048B (en) | Traditional Chinese medicine composition for treating chronic pelvic inflammation and preparation method thereof | |
| CN107536937B (en) | A topical Chinese medicinal liquid for treating dermatoses and onychomycosis, and its preparation method | |
| CN101129690A (en) | Decoction pieces for clearing heat and relieving swelling | |
| CN104825852A (en) | Tibetan medicine composition, preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: LIANGJI PHARMACEUTICAL CO., LTD., GUIZHOU PROV. Free format text: FORMER OWNER: GUIZHOU RONGFA PHARMACEUTICAL CO., LTD. Effective date: 20120509 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 550002 GUIYANG, GUIZHOU PROVINCE TO: 551206 QIANNAN BUYEI AND MIAO AUTONOMOUS PREFECTURE, GUIZHOU PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20120509 Address after: 551206 Longli County of Guizhou province Gujiao Pharmaceutical Industrial Park Patentee after: GUIZHOU LIANGJI PHARMACEUTICAL CO.,LTD. Address before: 550002, No. 21, building 2, building A, Lin Lin International Plaza, No. 196 Fu Nan Road, Guizhou, Guiyang Patentee before: GUIZHOU RONGFA PHARMACEUTICAL Co.,Ltd. |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20060322 |