CN100363030C - Chinese herbal preparation for killing fungus of fish, shrimp and crab - Google Patents

Abstract

The present invention discloses Chinese herbal preparation for killing fungi of fishes, shrimps and crabs, which is characterized in that the present invention comprises the following components of weight percent: 40 to 70% of Chinese gall, 10 to 30% of phellodendron, 10 to 30% of tree peony bark and 10 to 30% of houttuynia. The present invention is used for medically cleaning or fumigating fish bodies and fish eggs after being decocted. The components are interactive; the present invention has the advantages that (1) the present invention can be used as a medicine for preventing and treating water mold on the surfaces of fish bodies, shrimp bodies, crab bodies and fertilized eggs, the addition quantity is little, and the use is convenient; (2) water mold can be obviously removed, the recurrence of the water mold can be prevented, and thus, the survival rate of breeding organisms is improved; (3) a medically cleaning method and a fumigating method are continuously and alternately used, and then, the effect is good; (4) the raw materials which are used by the present invention have the advantages of stable sources and low cost and simple production technology; (5) no poisonous medicines residually exist in the fish bodies, the shrimp bodies and the crab bodies which are treated, and thus, fishes, shrimps and crabs can be eaten without generating toxic or side effect for human bodies; (6) the present invention not only can directly inhibit fungi, kill fungi, resist viruses and kill pests without generating medicine resistance, but also can regulate and improve organic immunity and can enhance the disease resistance of animal bodies.

Description

Fish, shrimp, Eriocheir sinensis antifungal Chinese herbal and crude drugs preparations

Technical field:

The present invention relates to a kind of Chinese herbal and crude drugs preparations, in especially a kind of raising that is applied to fish, shrimp, Eriocheir sinensis, have fish, shrimp, the Eriocheir sinensis antifungal Chinese herbal and crude drugs preparations of killing the mycete effect.

Background technology:

Fish molds is dermatomycosis again, belongs to fungal disease, is conditioned pathogen, extensively is present in the water body, is regardless of kind if Fish skin is injured and all can infects.The fish molds breeding has two kinds of forms, i.e. asexual propagation and sexual propagation, and wherein, asexual propagation generally carries out in water body, and sexual propagation is then infected the back at the fish body and is carried out in fish body body surface.After fish body skin damage is hindered, interior mycelia is attached to the injury region of fish body, draw Fish nutrition, and carry out sexual propagation, focus is enlarged rapidly, outside the growth fish body, form the Cotton Gossypii filament of white, because water mo(u)ld can secrete a large amount of mucus, make disease fish dysphoria, move about at last slowly, loss of appetite, the fish body is thin and weak and dead, fish molds is modal disease in the aquaculture, it is extremely strong to the appeal of germ cell in injured fish body and the hatching process, often causes the dead by the gross of germ cell, loses bigger.

At present, the control medicine that generally adopts for fish molds is a malachite green oxalate, but because malachite green oxalate has carcinogenic, teratogenesis, country has listed it in the row of forbidding fisheries drug.Along with the raising of living standards of the people and the enhancing gradually of environmental consciousness, people also constantly increase the demand of green non-pollution aquatic products.Chinese herbal medicine has been widely applied in the research and development of Fish medicine as a kind of green non-pollution means of production, and has demonstrated wide application prospect.Although though the research and development of Chinese herbal feed additive product have obtained certain progress, and the control to aquatic animal disease has effect preferably within the specific limits, but also unspecial shaping Chinese medicine preparation up to now, with stabilizing effect at fish molds.

Summary of the invention:

The present invention is directed to existing in prior technology does not have the technical problem of the shaping Chinese medicine preparation of special for treating fish molds, and a kind of Chinese herbal and crude drugs preparations that water mo(u)ld in fish, shrimp, the Eriocheir sinensis is had extremely strong lethality is provided.

Technical solution of the present invention is: a kind of fish, shrimp, Eriocheir sinensis antifungal Chinese herbal and crude drugs preparations is characterized in that raw material and percentage by weight are:

Galla Chinensis 40～70%

Cortex Phellodendri 10～30%

Cortex Moutan 10～30%

Herba Houttuyniae 10～30%.

The percentage by weight of raw material is preferably:

Galla Chinensis 60%

Cortex Phellodendri 20%

Cortex Moutan 10%

Herba Houttuyniae 10%.

Galla Chinensis is to be subjected to times aphid to stab parasitic insect gall on the leaf of plant Anacardiaceae Fructus rhois chinensis, blue or green bran poplar or Radix Rhois Sinicae etc. or the petiole.Gather autumn, boils dead insect gall endophyte worm, dries, and gives birth to and use.Contain Gallotannin 50～80%, gallic acid 2～5%, acid resin etc.Gallotannin can solidify and the former tannin of destruction of cancer cells, and the tool antitumor action all reaches more than 90% to the suppression ratio of murine sarcoma S-180; Acid resin has remarkable astriction to tissue ulcer such as mucocutaneous; And can quicken solidifying of blood stasis and be anastalsis; Decoct all has significantly antibacterial or bactericidal action to staphylococcus aureus, Diplococcus pneumoniae, streptococcus, Bacillus typhi, dysentery bacterium, diphtheria corynebacterium, anthrax bacillus, bacillus pyocyaneus etc.; The influenza first type PR strain virus that is inoculated in Embryo Gallus domesticus also there is inhibitory action.

Cortex Phellodendri is the bark of removing cork of Rutaceae deciduous tree plant Cortex Phellodendri (Cortex Phellodendri) and wampee (Cortex Phellodendri).The Cortex Phellodendri main product is in Liaoning, Jilin and other places.Resolving heat and reducing pathogenic fire dampness, bitter in the mouth, cold in nature, nontoxic.Its effective ingredient berberine, jateorhizine, magnoflorine, obacunone, obakulactone, Dictamnolide, obacunonic acid etc.Has a broad antifungal spectrum, all kinds of staphylococcuses, streptococcus, dysentery bacterium, Bacillus typhi and fungus all there is effect, in the above antibacterial action Hemolytic streptococcus, meningococcus, vibrio cholera, anthrax bacillus are had stronger inhibitory action, other has function of gallbladder promoting and strengthens the leukocytes phagocytic function.

The Cortex Moutan heat removing and blood cooling medicine, the acrid in the mouth hardship is slightly cold.Root contains paeonol, paeonolide, paeonolide, paeoniflorin.Still contain volatile oil 0.15～0.4% and plant sterol etc.Bright root contains the about 5%-6% of paeonolide, but easy enzymolysis becomes paeonolide and a part L-arabinose in drying and storage; Root bark also contains paeonol, paeoniflorin, hydroxypaeoniflorin, benzoylpaeoniflorin and benzoyl hydroxypaeoniflorin, volatile oil, and benzoic acid, plant sterol, sucrose, glucose, arabinose etc.To staphylococcus aureus, dysentery bacterium, typhoid fever, paratyphoid fever, green pus and escherichia coli and streptococcus and fungus all have inhibitory action, and blood pressure lowering, calmness, antiallergic and antiinflammatory action are arranged.

The Herba Houttuyniae heat and toxic materials clearing away medicine, acrid in the mouth acid is slightly cold.Bright grass contains volatile oil 0.005%, contains decanoylacetaldehyde, capraldehyde, lauryl aldehyde and methyl nonyl ketone etc. in the oil, and the former is a main component, but dry easily inefficacy.The Herba Swertiae davidi element is the main antimicrobial component of Herba Houttuyniae, and micrococcus catarrhalis, hemophilus influenza, streptococcus pneumoniae, staphylococcus aureus and some virus, fungus etc. are had obvious inhibitory action.In addition, Herba Houttuyniae also contains effective ingredient such as quercitrin, the effect with promoting diuresis and easing pain, hemostasis, raising immunity.

The present invention is the Chinese herbal medicine of a kind of special control fish, shrimp, Eriocheir sinensis fish molds, contains Chinese medicine ingredients such as Galla Chinensis, Cortex Phellodendri, Cortex Moutan, Herba Houttuyniae, is used for the dipping of fish body, fish roe or stifling after decocting.Each component interaction has following advantage: (1) as the control medication of fish, shrimp, Eriocheir sinensis body and germ cell surface fish molds, addition is little, and is easy to use; (2) significantly remove fish molds and prevent its recurrence, improve the survival rate of material culture; (3) dipping or stifling method uninterruptedly are used alternatingly better effects if; (4) its raw material source is stable, cheap, and production technology is simple; (5) no toxic medicament is residual in the fish, shrimp, Eriocheir sinensis body after treatment, food without any side effects to human body; (6) not only directly bacteriostasis and sterilization, antiviral, parasite killing do not produce drug resistance, and can regulate and human body immunity improving power, strengthen the resistance against diseases of animal body.

The specific embodiment:

Embodiment 1:

Get Galla Chinensis 40 grams, Cortex Phellodendri 20 grams, Cortex Moutan 20 grams, Herba Houttuyniae 20 grams, decocting method makes medicinal liquid routinely, in the dose input medicated bath pools with 10mg/L, fish, shrimp, Eriocheir sinensis and the germ cell thereof of infecting fish molds is treated, and it is evident in efficacy.

Embodiment 2:

Get Galla Chinensis 70 grams, Cortex Phellodendri 10 grams, Cortex Moutan 10 grams, Herba Houttuyniae 10 grams, decocting method makes medicinal liquid routinely, drop in the medicated bath pools or fumigate in hermetic container with the dose of 10mg/L, fish, shrimp, Eriocheir sinensis and the germ cell thereof of infecting fish molds are treated, it is evident in efficacy.

Embodiment 3:

Get Galla Chinensis 60 grams, Cortex Phellodendri 20 grams, Cortex Moutan 10 grams, Herba Houttuyniae 10 grams, decocting method makes medicinal liquid routinely, drop in the medicated bath pools or fumigate in hermetic container with the dose of 10mg/L, fish, shrimp, Eriocheir sinensis and the germ cell thereof of infecting fish molds are treated, it is evident in efficacy.

The body surface fish molds prevention effect of 1,2,3 pairs of green Odontobutis obscura germ cell of duck of the embodiment of the invention and Fugu rubripes (Temmincket Schlegel) is outstanding.

Table one Chinese herbal and crude drugs preparations is to the therapeutic effect of the green Odontobutis obscura germ cell of duck fish molds
					Lay eggs batches 12345	Infective dose (piece) 5,500 3,800 1,800 5,300 3200	Whether medication is	The amount of surviving (piece) 190 140 1,350 4,450 2750	Survival rate (%) 3.45 3.68 75.00 83.96 85.94

In crab (table two) germ cell is exsomatized embryo's hatching process, with the embryo that the processing of the embodiment of the invention 1,2,3 discontinuity is cut, can effectively preventing fish molds.

Table two Chinese herbal and crude drugs preparations is to the therapeutic effect of the stripped germ cell fish molds of Eriocheir sinensis
					Lay eggs batches 12345	Infective dose (piece) 102,600 92,600 124,700 154,600 101400	Whether medication is	The amount of surviving (piece) 5,540 4,630 62,350 58,748 25350	Survival rate (%) 5.4 5.0 50.0 38.0 25.0

Claims (2)

1. a fish, shrimp, Eriocheir sinensis antifungal Chinese herbal and crude drugs preparations is characterized in that raw material and percentage by weight are:

Galla Chinensis 40～70%

Cortex Phellodendri 10～30%

Cortex Moutan 10～30%

Herba Houttuyniae 10～30%.

2. fish according to claim 1, shrimp, Eriocheir sinensis antifungal Chinese herbal and crude drugs preparations is characterized in that the percentage by weight of raw material is:

Galla Chinensis 60%

Cortex Phellodendri 20%

Cortex Moutan 10%

Herba Houttuyniae 10%.