CN103405741B - Skin spray for pets and preparation method thereof - Google Patents
Skin spray for pets and preparation method thereof Download PDFInfo
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- CN103405741B CN103405741B CN201310370707.7A CN201310370707A CN103405741B CN 103405741 B CN103405741 B CN 103405741B CN 201310370707 A CN201310370707 A CN 201310370707A CN 103405741 B CN103405741 B CN 103405741B
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Abstract
The invention discloses a skin spray for pets and a preparation method thereof and belongs to the technical field of pet medicines. The spray disclosed by the invention comprises radix sophorae flavescentis, cortex pseudolaricis, radix euphorbiae lantu, long pepper, fructus kochiae, daemonorops draco, radix ampelopsis, pangolin, silky ant, biota tops, gallnut, polygonum multiflorum, saponin and dried ginger. The skin spray for the pets is prepared by decocting the raw materials of the formula in water, concentrating the decoction, then performing alcohol precipitation by 95% ethyl alcohol and finally performing stewing and filtering. By adopting the formula produced by pure natural plant raw materials, the skin spray can powerfully kill epizoa such as mite, louse and flea, can effectively realize bacteriostasis and itching relieving and resist allergic diseases of skin, is mild in property, is used safely and conveniently and can effectively promote reproduction of furs of the pets. According to the method, the technology is simple; requirements on equipment are low; the environment friendliness is realized; the method is suitable for industrial expanded production.
Description
Technical field
The invention belongs to house pet medical art, be specifically related to a kind of house pet skin spray and preparation method thereof.
Background technology
All select domestic pets in increasing family, keep a pet and become a kind of fashion already.Keep a pet and be also faced with some common house pet diseases, and house pet disease is easy and people suffers from the disease cross infection, makes zoonosis increase year by year, the infectious disease and more than the 150 kind of parasitic disease that there will be a known more than 200 kinds at present threaten human health.Mainly contain pathogenic bacteria, parasite, pathogenic dermatophytes etc., house pet pathogen mainly intersperses among the position such as fur, skin trouble, hole key, extremity of house pet, brings the source of infection of disease to owner.
Pet skin disease becomes the common disease of the family of numerous pet feeding, house pet is due to hair own, skin properties, the pathogen such as antibacterial, fungus, virus, parasite are made very easily to be originated in pet hair and skin surface, cause house pet ill, have influence on the health of house pet and owner, at present, for the house pet suffering from skin disorder, common spray mostly is synthetic, toxic and side effects is larger, therefore, the aspects such as house pet route of administration, drug effect, toxic and side effects are considered, that need a kind of applicable house pet external badly, that toxic and side effects is little house pet medicine.
Summary of the invention
The object of the present invention is to provide a kind of house pet skin spray and preparation method thereof, this skin spray adopts natural Chinese medicine formula, can effectively kill Pet fur pathogen, bacterio static itching-relieving successful, safe and convenient to use.
The present invention is achieved through the following technical solutions:
A kind of house pet skin spray, this spray of every 1000ml is by Radix Sophorae Flavescentis 100 ~ 120g, Cortex Pseudolaricis 80 ~ 100g, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 80 ~ 90g, Fructus Piperis Longi 60 ~ 80g, the Fructus Kochiae 50 ~ 60g, Sanguis Draxonis 30 ~ 40g, Radix Ampelopsis 80 ~ 90g, Squama Manis 60 ~ 80g, Formica fusca 60 ~ 80g, Cacumen Platycladi 30 ~ 50g, Galla Chinensis 30 ~ 50g, Radix Polygoni Multiflori 30 ~ 50g, through decocting, filtering, to obtain after concentrated, precipitate with ethanol after Fructus Gleditsia 30 ~ 50g, Rhizoma Zingiberis 30 ~ 50g mixing.
A preparation method for house pet skin spray, comprises the following steps:
1) Radix Sophorae Flavescentis 100 ~ 120g is got, Cortex Pseudolaricis 80 ~ 100g, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 80 ~ 90g, Fructus Piperis Longi 60 ~ 80g, the Fructus Kochiae 50 ~ 60g, Sanguis Draxonis 30 ~ 40g, Radix Ampelopsis 80 ~ 90g, Squama Manis 60 ~ 80g, Formica fusca 60 ~ 80g, Cacumen Platycladi 30 ~ 50g, Galla Chinensis 30 ~ 50g, Radix Polygoni Multiflori 30 ~ 50g, Fructus Gleditsia 30 ~ 50g, Rhizoma Zingiberis 30 ~ 50g, mixing, obtains compound;
2) add water in compound and decoct, then filter, collect filtrate;
3) filtrate being concentrated into relative density is after the thick paste of 1.1 ~ 1.3, adds purified water and volume fraction is after the ethanol of 95% in thick paste, leaves standstill, then leaching filtrate is crossed, filtrate is settled to 1000ml, and makes ethanol content in filtrate reach 70% ~ 75%, obtain house pet skin spray.
Step 2) described in decoction carry out at twice, first time adds the soak by water 2 ~ 4h of mixture quality 6 ~ 8 times, and second time adds the water of mixture quality 5 ~ 7 times, continues decoction 1 ~ 3h.
The described temperature decocted with water is 80 ~ 100 DEG C.
Time of repose described in step 3) is 12 ~ 24h.
Compared with prior art, the present invention has following useful technique effect:
The present invention adopt Radix Sophorae Flavescentis, Cortex Pseudolaricis, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), Piper longum, the Fructus Kochiae, Sanguis Draxonis, Squama Manis, etc. pure natural animals and plants Chinese medicine formula, Radix Sophorae Flavescentis has the effect of parasite killing, heat clearing and damp drying, effectively can suppress eczema, eczema, skin pruritus, scabies leprosy; Cortex Pseudolaricis all has certain antibacterial action to more than the 10 kind of pathomycete that house pet is common, and the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) can removing mass parasite killing, and the Fructus Kochiae can except skin inner product warm, pruritus due to damp pathogen apart from skin; Sanguis Draxonis has stronger bacteriostasis to pathogenic coccus and bacillus; Radix Ampelopsis all has inhibitory action in various degree to common house pet dermatophytes of causing a disease; Squama Manis can detumescence and apocenosis, and Formica fusca has removing toxic substances, analgesia, itching-relieving efficacies; Cacumen Platycladi has hair growth promoting function, effectively can promote that house pet fur regenerates.Galla Chinensis, Radix Polygoni Multiflori, the kidney invigorating benefit blood, hair care hair care, promotes hair growth.Spina Gleditsiae, Rhizoma Zingiberis expelling wind and activating blood circulation, the unobstructed meridians of energy, accelerate circulation, activate hair follicle, can promote the excretion of the absorption of skin histology nutrition and waste material, improve scalp ecology.By the formula that these pure natural animal-plant materials are formed, not only brute force the ectozoaes such as demodicid mite, louse, flea can be killed, can also effectively antibacterial, antipruritic, antagonism allergic skin illness, and this product character is gentle, safe and convenient to use, total effective rate reaches more than 98%.
The present invention prepares the method for house pet skin spray, and technique is simple, low for equipment requirements, environmental friendliness, is applicable to industrial amplification production.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail, and the explanation of the invention is not limited.
Embodiment 1
A preparation method for house pet skin spray, comprises the following steps:
1) Radix Sophorae Flavescentis 120g is got, Cortex Pseudolaricis 100g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 90g, Fructus Piperis Longi 80g, Fructus Kochiae 60g, Sanguis Draxonis 40g, the Squama Manis of artificial cultivation taken from by the Squama Manis medical material that Radix Ampelopsis 90g, the Squama Manis 80g(embodiment of the present invention adopts), Formica fusca 80g, Cacumen Platycladi 50g, Galla Chinensis 50g, Radix Polygoni Multiflori 50g, Fructus Gleditsia 50g, Rhizoma Zingiberis 50g, mixing, obtains compound;
2) in compound, add the water of mixture quality 6 times, at 100 DEG C, decoct 4h, and then add the water of mixture quality 5 times, continue to decoct 3h at 100 DEG C, then filter, collect filtrate;
3) filtrate being concentrated into relative density is after the thick paste of 1.2, adds purified water and volume fraction is after the ethanol of 95% in thick paste, leaves standstill, then leaching filtrate is crossed, filtrate is settled to 1000ml, and makes ethanol content in filtrate reach 70%, obtain house pet skin spray.
Embodiment 2
A preparation method for house pet skin spray, comprises the following steps:
1) get Radix Sophorae Flavescentis 100g, Cortex Pseudolaricis 80g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 80g, Fructus Piperis Longi 60g, Fructus Kochiae 50g, Sanguis Draxonis 30g, Radix Ampelopsis 80g, Squama Manis 60g, Formica fusca 60g, Cacumen Platycladi 30g, Galla Chinensis 30g, Radix Polygoni Multiflori 30g, Fructus Gleditsia 30g, Rhizoma Zingiberis 30g, mixing, obtains compound;
2) in compound, add the water of mixture quality 7 times, at 90 DEG C, decoct 3h, and then add the water of mixture quality 6 times, continue to decoct 2h at 90 DEG C, then filter, collect filtrate;
3) filtrate being concentrated into relative density is after the thick paste of 1.1, adds purified water and volume fraction is after the ethanol of 95% in thick paste, leaves standstill, then leaching filtrate is crossed, filtrate is settled to 1000ml, and makes ethanol content in filtrate reach 75%, obtain house pet skin spray.
Embodiment 3
A preparation method for house pet skin spray, comprises the following steps:
1) get Radix Sophorae Flavescentis 110g, Cortex Pseudolaricis 90g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 85g, Fructus Piperis Longi 80g, Fructus Kochiae 50g, Sanguis Draxonis 70g, Radix Ampelopsis 83g, Squama Manis 60g, Formica fusca 70g, Cacumen Platycladi 50g, Galla Chinensis 50g, Radix Polygoni Multiflori 50g, Fructus Gleditsia 45g, Rhizoma Zingiberis 50g, mixing, obtains compound;
2) in compound, add the water of mixture quality 8 times, at 80 DEG C, decoct 2h, and then add the water of mixture quality 7 times, continue to decoct 1h at 80 DEG C, then filter, collect filtrate;
3) filtrate being concentrated into relative density is after the thick paste of 1.3, adds purified water and volume fraction is after the ethanol of 95% in thick paste, leaves standstill, then leaching filtrate is crossed, filtrate is settled to 1000ml, and makes ethanol content in filtrate reach 75%, obtain house pet skin spray.
Embodiment 4
A preparation method for house pet skin spray, comprises the following steps:
1) get Radix Sophorae Flavescentis 110g, Cortex Pseudolaricis 95g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 85g, Fructus Piperis Longi 85g, Fructus Kochiae 55g, Sanguis Draxonis 65g, Radix Ampelopsis 90g, Squama Manis 70g, Formica fusca 68g, Cacumen Platycladi 30g, Galla Chinensis 45g, Radix Polygoni Multiflori 35g, Fructus Gleditsia 50g, Rhizoma Zingiberis 35g, mixing, obtains compound;
2) in compound, add the water of mixture quality 6 times, at 100 DEG C, decoct 4h, and then add the water of mixture quality 5 times, continue to decoct 1h at 90 DEG C, then filter, collect filtrate;
3) filtrate being concentrated into relative density is after the thick paste of 1.2, adds purified water and volume fraction is after the ethanol of 95% in thick paste, leaves standstill, then leaching filtrate is crossed, filtrate is settled to 1000ml, and makes ethanol content in filtrate reach 73%, obtain house pet skin spray.
House pet the present invention obtained carries out the test of pesticide effectiveness with after skin spray tinning, as follows:
Choose and suffer from dermopathic pet dog 15, obtained spray is sprayed directly on to the affected part of ill Canis familiaris L., each 2 ~ 3 sprays, every day 3 ~ 5 times, use 3 weeks continuously.Clinical observation treatment effect, as shown in table 1 below:
The house pet that table 1 the present invention obtains skin spray therapeutic effect information slip
| First week | Second week | 3rd week | |
| Cure rate (%) | 37.40 | 67.50 | 98.00 |
| Obvious effective rate (%) | 45.60 | 26.40 | 2.00 |
| Effective percentage (%) | 15.00 | 6.10 | 0 |
| Inefficiency (%) | 2.00 | 0 | 0 |
As can be seen from the above table, house pet skin spray prepared by the present invention is remarkable to the therapeutic effect of ill Canis familiaris L., treat after one week and observe, its total effective rate just reaches 98%, (total effective rate=cure rate+obvious effective rate+effective percentage) and ill Canis familiaris L. over the course for the treatment of, have no adverse reaction, safe and reliable.
Raw material of the present invention all adopts natural Chinese medicine, and raw material resources are enriched, and have no side effect.Radix Sophorae Flavescentis has the effect of parasite killing, heat clearing and damp drying, effectively can suppress eczema, eczema, skin pruritus, scabies leprosy; Cortex Pseudolaricis all has certain antibacterial action to more than the 10 kind of pathomycete that house pet is common, and to being permitted, blue achorion, acrothesium floccosum, rust little spore tinea bacterium, microsporon gypseum and Candida albicans bactericidal action are obvious; The Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) can removing mass parasite killing, and the Fructus Kochiae can except skin inner product warm, pruritus due to damp pathogen apart from skin; Sanguis Draxonis has very strong bacteriostasis to staphylococcus aureus, Staphylococcus albus, Staphylococcus citreus, Nai Shi coccus, diphtheria corynebacterium and Bacillus typhi; Stronger bacteriostasis is had to escherichia coli, bacillus pyocyaneus, shigella flexneri etc.; Radix Ampelopsis all has inhibitory action in various degree to the dermatophytes such as trichophyton, trichophyton gypseum, perhaps blue achorion, Du's big belly microspore tinea bacterium difficult to understand, rust microspore tinea bacterium, ulotrichy microspore tinea bacterium, epidermophyton inguinale, epidermophyton rubrum, Candida albicans, star-shaped nocardia; Squama Manis can detumescence and apocenosis, and Formica fusca has removing toxic substances, analgesia, itching-relieving efficacies; Cacumen Platycladi has hair growth promoting function, effectively can promote that house pet fur regenerates.Galla Chinensis, Radix Polygoni Multiflori, the kidney invigorating benefit blood, hair care hair care, promotes hair growth.Spina Gleditsiae, Rhizoma Zingiberis expelling wind and activating blood circulation, the unobstructed meridians of energy, accelerate circulation, activate hair follicle, can promote the excretion of the absorption of skin histology nutrition and waste material, improve fur ecology.
In sum, the present invention adopts the animal and plant extract of these pure naturals, has Efficient antibacterial itching-relieving action and kills demodicid mite effect, can effectively promote that fur regenerates simultaneously, proves that this house pet total effective rate of skin spray reaches more than 98% by test.
Claims (5)
1. a house pet skin spray, is characterized in that, this spray of every 1000ml is by Radix Sophorae Flavescentis 100 ~ 120g, Cortex Pseudolaricis 80 ~ 100g, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 80 ~ 90g, Fructus Piperis Longi 60 ~ 80g, the Fructus Kochiae 50 ~ 60g, Sanguis Draxonis 30 ~ 40g, Radix Ampelopsis 80 ~ 90g, Squama Manis 60 ~ 80g, Formica fusca 60 ~ 80g, Cacumen Platycladi 30 ~ 50g, Galla Chinensis 30 ~ 50g, through decocting, filtering, to obtain after concentrated, precipitate with ethanol after Radix Polygoni Multiflori 30 ~ 50g, Fructus Gleditsia 30 ~ 50g, Rhizoma Zingiberis 30 ~ 50g mixing.
2. a preparation method for house pet skin spray, is characterized in that, comprises the following steps:
1) Radix Sophorae Flavescentis 100 ~ 120g is got, Cortex Pseudolaricis 80 ~ 100g, the Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 80 ~ 90g, Fructus Piperis Longi 60 ~ 80g, the Fructus Kochiae 50 ~ 60g, Sanguis Draxonis 30 ~ 40g, Radix Ampelopsis 80 ~ 90g, Squama Manis 60 ~ 80g, Formica fusca 60 ~ 80g, Cacumen Platycladi 30 ~ 50g, Galla Chinensis 30 ~ 50g, Radix Polygoni Multiflori 30 ~ 50g, Fructus Gleditsia 30 ~ 50g, Rhizoma Zingiberis 30 ~ 50g, mixing, obtains compound;
2) add water in compound and decoct, then filter, collect filtrate;
3) filtrate being concentrated into relative density is after the thick paste of 1.1 ~ 1.3, adds purified water and volume fraction is after the ethanol of 95% in thick paste, leaves standstill, then leaching filtrate is crossed, filtrate is settled to 1000ml, and makes ethanol content in filtrate reach 70% ~ 75%, obtain house pet skin spray.
3. the preparation method of a kind of house pet skin spray according to claim 2, it is characterized in that, step 2) described in decoction carry out at twice, first time adds the soak by water 2 ~ 4h of mixture quality 6 ~ 8 times, second time adds the water of mixture quality 5 ~ 7 times, continues decoction 1 ~ 3h.
4. the preparation method of a kind of house pet skin spray according to claim 3, is characterized in that, the described temperature decocted with water is 80 ~ 100 DEG C.
5. the preparation method of a kind of house pet skin spray according to claim 2, is characterized in that, the time of repose described in step 3) is 12 ~ 24h.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310370707.7A CN103405741B (en) | 2013-08-22 | 2013-08-22 | Skin spray for pets and preparation method thereof |
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| CN201310370707.7A CN103405741B (en) | 2013-08-22 | 2013-08-22 | Skin spray for pets and preparation method thereof |
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| CN103405741A CN103405741A (en) | 2013-11-27 |
| CN103405741B true CN103405741B (en) | 2015-05-06 |
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| CN106434058A (en) * | 2016-08-28 | 2017-02-22 | 骆志明 | Pure traditional Chinese medicine pet caring rebatching soap |
| CN111773367A (en) * | 2020-08-12 | 2020-10-16 | 安徽氧趣生物科技有限公司 | Compound preparation for treating animal skin diseases and preparation method thereof |
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| CN1436563A (en) * | 2002-11-15 | 2003-08-20 | 贵州同康药业有限公司 | Skin-cleaning and itch-stopping tincture as externally applied medicine for treating skin pruritus |
| CN101274093A (en) * | 2008-05-06 | 2008-10-01 | 广冬云 | Chinese medicine for curing fungal dermatopathy |
| CN101342262A (en) * | 2008-08-28 | 2009-01-14 | 北京天科仁祥医药科技有限公司 | Gelling agent for treating skin pruritus |
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