CN104489279A - Chinese traditional herb feed additive for treating cow mastitis - Google Patents

Chinese traditional herb feed additive for treating cow mastitis Download PDF

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Publication number
CN104489279A
CN104489279A CN201510019502.3A CN201510019502A CN104489279A CN 104489279 A CN104489279 A CN 104489279A CN 201510019502 A CN201510019502 A CN 201510019502A CN 104489279 A CN104489279 A CN 104489279A
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parts
feed additive
milk
chinese herbal
mastitis
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高桂生
史秋梅
梁思嘉
高光平
邵欣华
张艳英
梁娜
梁银聚
安永林
卢彦荣
冯芳
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HEBEI HANNUO PHARMACEUTICAL Co Ltd
Hebei Normal University of Science and Technology
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HEBEI HANNUO PHARMACEUTICAL Co Ltd
Hebei Normal University of Science and Technology
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Abstract

The invention provides a Chinese traditional herb feed additive for treating cow mastitis. The Chinese traditional herb feed additive is a preparation prepared from the following raw materials in parts by weight: 5 to 7 parts of houttuynia cordata, 4 to 6 parts of brooklet anemone root, 4 to 6 parts of fructus liquidambaris, 3 to 5 parts of loofah sponge, 3 to 5 parts of cowherb seed, 2 to 4 parts of root of common peony, 2 to 4 parts of radix scrophulariae, 2 to 4 parts of frankincense, 2 to 4 parts of myrrh, 2 to 4 parts of echinacea, 2 to 4 parts of astragalus membranaceus, and 1 to 2 parts of liquorice. The Chinese traditional herb feed additive is used for treating cow mastitis, and has the characteristics of being short in course of treatment, low in cost, high in cure rate, safe, free of toxic and side effects, and convenient to take.

Description

The Chinese herbal feed additive for the treatment of mastitis for milk cows
Technical field
The present invention relates to the Chinese herbal and crude drugs preparations of milk cattle cultivating, be specifically related to a kind of Chinese herbal feed additive for the treatment of mastitis for milk cows.
Background technology
Mammitis is the common principal disease of harm milk cow health.The pathogenic microorganism of mastitis for milk cows reaches kind more than 80, comparatively common are 23 kinds, wherein 14 kinds, bacterium, Mycoplasma 2 kinds, fungi and 7 kinds, virus, but 80% ~ 90% is caused by staphylococcus and streptococcus.The loss that mammitis causes mainly comprises milk production and reduces, and milk-quality reduces, and milk is discarded, and increases the cost of standby milk cow, additional labor expense, medicine spending and veterinary service expense etc.China's clinic mastitis incidence of disease is 21% ~ 23%, and the subclinical mastitis incidence of disease is about 50%.At present, what the employing for the treatment of mastitis for milk cows was more is Antibiotics Western medicine, although have certain curative effect, shortcoming is that the resistance to the action of a drug and side effect are comparatively serious, and in meat and milk, have chemicals residual, brings potential threat to human health; Chinese herbal medicine have natural, have no side effect, residual without chemicals, not easily the feature such as to develop immunity to drugs, for mastitis for milk cows diseases prevention, cure the disease, be with a wide range of applications.But the Chinese herbal medicine being used for the treatment of mastitis for milk cows commercially available at present, result of use is poor, and cure rate is low, and the course for the treatment of is long and cost is high.
Summary of the invention
The object of the invention is to for the problems referred to above, provide a kind of easy to use, cost is low, effectively can treat the Chinese herbal feed additive of mastitis for milk cows.
Technical scheme of the present invention is: a kind of Chinese herbal feed additive for the treatment of mastitis for milk cows, and it makes medicament by the raw material of following weight parts: cordate houttuynia 5 parts-7 parts, brook anemone 4 parts-6 parts, play both sides of the street 4 parts-6 parts, luffa 3 parts-5 parts, the seed of cowherb 3 parts-5 parts, the radix paeoniae rubrathe 2 parts-4 parts, radix scrophulariae 2 parts-4 parts, frankincense 2 parts-4 parts, myrrh 2 parts-4 parts, Echinacea 2 parts-4 parts, the Radix Astragali 2 parts-4 parts, 1 part-2 parts, Radix Glycyrrhizae.
The preferred feedstock weight portion of the Chinese herbal feed additive of cost treatment mastitis for milk cows processed is: cordate houttuynia 7 parts, and brook anemone 6 parts plays both sides of the street 6 parts, luffa 4 parts, the seed of cowherb 4 parts, the radix paeoniae rubrathe 2 parts, radix scrophulariae 2 parts, frankincense 2 parts, myrrh 2 parts, Echinacea 2 parts, the Radix Astragali 2 parts, 1 part, Radix Glycyrrhizae.
In the Chinese herbal feed additive prescription of this treatment mastitis for milk cows, each component pharmacological effect is:
Cordate houttuynia effect: the cordate houttuynia another name folding basal part of the ear, smelly dish, root of picking up the ears, smelly grass, laggera pterodonta, Zhu's skin arch etc.Cold nature, bitter, returns lung channel, bladder, large intestine channel.Containing volatile oil, wherein effective ingredient is decanoyl acetaldehyde and decanoy acetaldehyde, lauryl aldehyde, methyln nonyl ketone, cloves alkene, linalool, Bronyl acetate, australene, amphene, laurene and (R)-4-isopropenyl-1-methyl-1-cyclohexene, methyl n nonyl ketone, capraldehyde, capric acid etc.Also has Quercetin, quercitrin, Isoquercitrin, reynoutrin, hyperin, afzerin, rutin.Still containing chlorogenic acid, palmitic acid, oleic acid, oleic acid, potassium chloride, sulfuric acid, and cupreol etc.Tool is clearing heat and detoxicating, removing pus and relieving carbuncle, effect of inducing diuresis for treating strangurtia; For lung carbuncle pyemesis, phlegm heat panting is coughed, hot dysentery, carbuncle sore tumefacting virus etc.
Brook anemone effect: brook anemone is called small stream side pasqueflower, sees that wind is blue or green, sees wind indigo plant etc., and property is pungent, bitter is cold, returns lung, stomach, Liver Channel.Containing betulic acid, anemone rivularis saponin, brook anemone saponin A, B, C, D and saponin AR-1, AR-3 etc.Tool is clearing heat and detoxicating, kobadrin, the effect of activating blood and relaxing tendons.For abscess of throat, coughing with a lot of sputum, scrofula, tuberculosis, swollen ulcer drug, malaria, rheumatalgia, stomachache, dysentery, traumatic injury etc.
Play both sides of the street effect: on play both sides of the street another name nine Confucius maple reality, maple, ball, sweetgum fruit, maple fruit, chicken maple, Japanese maple, great Ye maple, six are led to.Nature and flavor are bitter, flat, return liver kidney channel.Remove first oleanonic acid containing 28-, styracin, left-handed cinnamic acid borneol acetate, epoxy styracin, different epoxy styracin, trans-Caryophyllene oxide, play both sides of the street ketone acid, 24-ethyl courage steroid-5-enol.Tool dispelling, collateral-activating, Li Shui stimulates the menstrual flow, effect of the promoting flow of qi and blood circulation.For joint pain, numbness contracture, oedema turgor, breast is few.
Luffa effect: luffa another name sponge gourd net, sponge gourd shell, melon network, nature and flavor are sweet flat, cold.Return through stomach, lung, Liver Channel.Containing luffa containing xylan, mannosan, galactan etc. and saponins, luffein, lymphatic temperament, wood glue, citrulling, xylan and interferon etc.Tool dispelling wind and removing obstruction in the meridians, the effect of lactogenesis of invigorating blood circulation.Be used for the treatment of the contraction of numbness pain, distending pain in the chest and hypochondrium, alactation, acute mastitis swells and ache.
Seed of cowherb effect: seed of cowherb another name cow-fat, milk rice, barley ox, not femalely to stay, king cow, SEMEN VACCARIAE etc.Nature and flavor hardship is flat, returns liver, stomach warp.Containing triterpenoid saponin, what be called vacsedoside has A, B, C, D4 kind, the polysaccharid glucoside all for being derived by gypsogenin.Again containing glycosides displayed, also containing phytin, phosphatide, stigmasterol etc.Effect of tool activating blood to promote menstruation, the not newborn carbuncle that disappears.Swell for alactation, acute mastitis, carbuncle.
Radix paeoniae rubrathe effect: the radix paeoniae rubrathe calls wooden Chinese herbaceous peony, careless Chinese herbaceous peony, red Chinese herbaceous peony, the comospore radix paeoniae rubrathe etc., nature and flavor are bitter, are slightly cold, return Liver Channel.Containing Paeoniflorin and paeonolide.Also containing benzoic acid, volatile oil, fat oil, resin, tannin, sugar, starch, mucilaginous substance, protein etc.Tool clearing heat and cooling blood, effect of blood stasis removing analgesic.Enter ying blood for heat, febrile virulent maculae, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, addiction lump in the abdomen is suffered from abdominal pain, injury from falling down, and carbuncle swells sore etc.
Radix scrophulariae effect: radix scrophulariae another name radix scrophulariae, Zhejiang radix scrophulariae, black ginseng, heavy platform, ghost Tibetan, positive horse, deer intestines etc.Property bitter but sweet flavor, salty, cold, return lung, stomach, kidney channel.Containing iridoids, Phenylpropanoid Glycosides glycoside, still containing the monoterpene of phytosterol, organic acid, flavonoids, triterpenoid saponin, volatile oil, carbohydrate, alkaloid and trace and Diterpene etc.Effect of tool clearing heat and cooling blood, nourishing Yin and falling fire, detoxicating and resolving a mass.For warm heat disease heat and ying blood, body heat, polydipsia, tongue is deep red, and send out spot, hectic fever due to yin labor is coughed, and constipation is hindered in Tianjin, and order is puckery dim-sighted, abscess of throat, scrofula subcutaneous nodule, skin sore etc.
Frankincense effect: the smoked Lu Xiang of frankincense another name, horse hair is fragrant, nipple is fragrant, the perfume (or spice) that collapses, sky pool is fragrant, Moller is fragrant, many gals Luo Xiang etc., property is arduous, warm, enters the heart, liver, the spleen channel.Resinous, natural gum, volatile oil; The main component of resin is free α-boswellic acid, β-boswellic acid, in conjunction with boswellic acid, olibanoresene; Natural gum is calcium salt and magnesium salts, western Radix Astragali gluing element and the amaroid of arabitic acid; Volatile oil is containing firpene, amphene, sabinene, elemene, racemization-citrene and α-phellandrene etc.Effect of tool blood-activating and qi-promoting, pain relieving.For regulating qi and activating blood, analgesic therapy, chases after poison etc.Control qi and blood stagnation, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury etc.
Myrrh effect: myrrh another name myrrh.Nature and flavor toil, temperature, the thoughts of returning home, liver,spleen,kidney warp.Resinous, volatile oil, natural gum.The major part of resin can be dissolved in ether, and volatile oil is resinophore in atmosphere, containing Eugenol, and m-cresol, cumaldehyde, firpene, citrene, cinnaldehydrum etc., and containing multiple furan sesquiterpene compounds, natural gum is hydrolyzed to obtain arabinose, galactolipin and wood sugar.The effects such as tool promoting blood circulation and stopping pain, detumescence and promoting granulation.To swell sore, acute appendicitis, red eye, swell pain etc. for chest abdomen stasis of blood pain, traumatic injury, carbuncle.
Echinacea effect: Echinacea another name Echinacea purpurea, Echinacea, purple coneflower, the flat taste of property is sweet, returns lung, the spleen channel.Echinacea contains polysaccharide, flavones, caffeinic derivative, essential oil, polyyne, alkylamine and alkaloid.Echinacea has immunostimulation, reduces inflammation, and helps body fight bacterium and virus.Related tests shows to use Echinacea feeding animals, can improve the phagocytic activity of neutrophil cell and the quantity of periphery lymphocyte, the immunocompetence of effective stimulus animal body; Echinacea root is made feed addictive and feed chicken, obviously can increase the infection rate of experimental group body weight and reduction coccidia.
Radix Astragali effect: cotton stilbene called by the Radix Astragali, yellow over sixty years of age, only mulberry, another name for Sichuan Province fat, hundred, hundred absorbent cotton etc.Nature and flavor are sweet, tepor.Return lung, spleen, liver, kidney channel.The Radix Astragali containing saponin, flavones, polysaccharide, several amino acids, folic acid and selenium, zinc, the various trace elements such as copper, there is enhanced machine body immunity function, protect the liver, diuresis, step-down, anti-ageing, anti anoxia, radioresistance, resisting stress, low temperature resistant and high temperature resistant effect.
Radix Glycyrrhizae effect: Radix Glycyrrhizae mainly containing the composition such as glycyrrhizic acid, glycyrrhizin, 24-hydroxyl enoxolone, licoflavone, glycyrrhizin, isoliquiritigenin, licorice polysaccharide, there is antiulcer, promote pancreatic secretion, protect the liver, lipopenicillinase, adjustment macrophage the effect such as phagocytic function.Glycyrrhizic acid is natural antidote, can be used for that body is anti-ageing, develop immunitypty, maintenance water-electrolyte metabolism balance etc.; Licorice polysaccharide has anti-adenovirus type III, herpes simplex virus I-form is active.Have and invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, effect of coordinating the drug actions of a prescription.For weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, the anxious pain of gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The Chinese herbal feed additive prescription foundation of this treatment mastitis for milk cows: mammitis and acute mastitis is phlegm, wet, gas, blood stasis knot does not fall apart, and changes and is scorching.Or because of hyperpyrexia of stomach, stagnation of QI due to depression of the liver, newborn network loses smooth so that breast qi and blood stagnation, stasis and raw carbuncle swells; Or be not good at because of feeding and management, sleeping damp and hot ground, damp and hot poison gas steams for a long time, infringement breast; And recessive mastitis is many because of body insufficiency of vital energy and blood, again caused by being invaded by exogenous pathogen,invasion of exogenous pathogen.Therefore, prescription should with promoting blood circulation and removing blood stasis, clearing heat and detoxicating, dispersing swelling and dissipating binds, lactogenesis of stimulating the menstrual flow for principle.Play both sides of the street, luffa, seed of cowherb hardship rush down to fall, sweet with removing toxic substances, cold can heat-clearing, hold concurrently with logical breast, be the key medicine controlling acute mastitis, containing multiple health-nutrition compositions such as alcohol, choline, organic acid, sugar in these plants, there is clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia effect; Cordate houttuynia, brook anemone have the effect of stronger anti-inflammation, clearing heat and detoxicating, removing pus and relieving carbuncle; Cordate houttuynia, brook anemone, the radix paeoniae rubrathe, radix scrophulariae, frankincense, myrrh have more clearing heat and detoxicating, anti-inflammation, promoting blood circulation and stopping pain, detumescence and promoting granulation, live through the effect of dredging collateral.Echinacea, Radix Astragali enhanced machine body immunity function, altogether with the sweet Wen Yiqi of Radix Glycyrrhizae and middle invigorating the spleen, current twelve channels and collaterals, coordinating the drug actions of a prescription.In side all medicine phases and, play promoting blood circulation and removing blood stasis, clearing heat and detoxicating, anti-inflammation, dispersing swelling and dissipating binds, lactogenesis of stimulating the menstrual flow altogether, improve effect of immunity of organisms and resistance against diseases.Be applicable to the mastitis for milk cows that a variety of causes causes.For convenience of using, make pulvis.
The Chinese herbal feed additive of this treatment mastitis for milk cows, on the basis of carrying out a large amount of practical application, according to traditional medicine ancient prescription, form in conjunction with modern popular disease, aetology and immunologic theory screening, be used for the treatment of mastitis for milk cows, short treating period, cost be low, cure rate is high, safely, have no side effect, easy to use.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment:
Take raw material (medicine materical crude slice) respectively: cordate houttuynia 175g, brook anemone 150g, play both sides of the street 150g, luffa 100g, seed of cowherb 100g, radix paeoniae rubrathe 50g, radix scrophulariae 50g, frankincense 50g, myrrh 50g, Echinacea 50g, Radix Astragali 50g, Radix Glycyrrhizae 25g.
Above-mentioned raw materials is ground into Chinese herbal medicine meal respectively, mixing, packaging, i.e. the Chinese herbal feed additive of obtained this treatment mastitis for milk cows.
Some test situation utilizing the Chinese herbal feed additive of this treatment mastitis for milk cows to carry out are as follows:
1, this Chinese herbal feed additive is to the drug sensitive test of cow subclinical mastitis the main pathogenic fungi
Choose clinical trouble recessive mastitis milk cow case, through being separated, identifying, select pathogenic 2 kinds of stronger pathogens as staphylococcus aureus and Streptococcusagalactiae.Take a certain amount of Chinese herbal feed additive, add 10 times amount distilled water heating and refluxing extraction 2 times, each 0.5h, merge secondary filtrate, be evaporated to 1mL liquid and be equivalent to crude drug in whole 1.0g (1g/mL), 100 DEG C of boiling sterilizations, 4 DEG C save backup.The staphylococcus aureus of clinical separation, Streptococcusagalactiae are first inoculated in flat board, after cultivating 18h, select colonies typical and be inoculated in 5mL meat soup in 37 DEG C, after cultivating 18h in 37 DEG C, bacterium liquid, than turbid, is diluted to 10 with meat soup by 0.5 Maxwell unit norm opacity tube 6cFU/mL, for subsequent use.
(1) medicament sensitivity test adopts plate punch method, adds the crude drug extract of this Chinese herbal feed additive of 1g/mL in hole, is not advisable outside overfolw hole to fill it up with.Separately get penicillin 10IU/ sheet, ampicillin 5 μ g/mL, Ciprofloxacin 1 μ g/mL tri-kinds of antibiotic drug sensitive tests compare, be placed in 37 DEG C of constant incubators and cultivate 24h, measure antibacterial circle diameter, the drug sensitive test of often kind of medicine in triplicate.Criterion: according to " pharmacology of Chinese materia medica " standard with " U.S. clinical Laboratory Standard research institute version in 2005 is about drug sensitive test standardization ", namely bacteriostatic diameter >=20mm is extremely quick, and 20mm> bacteriostatic diameter >=15mm is Gao Min; 15mm> bacteriostatic diameter >=10mm is quick in being, below 10mm is muting sensitive.
(2) the mensuration micro-dilution method of minimal inhibitory concentration (MIC): 96 orifice plates through sterilization are often arranged in each hole of 1-10, the crude drug extract of this Chinese herbal feed additive with meat soup doubling dilution is added successively with micropipettor, every hole 200 μ L, totally 10 different concentration, then in every hole, dilution bacterium liquid 10 μ L is added, the 11st, 12 holes are respectively negative control group (not adding pathogenetic bacteria) and positive controls (not adding medicine).Be placed in 1min that oscillator vibrates, make after in hole, solution fully mixes, microwell plate is placed on after adding a cover the sealing of blend compounds paper and is covered with in the square enamel tray of wet gauze, in 37 DEG C of incubators, hatch 18h, observes lowest concentration of drug contained by asepsis growth hole be minimal inhibitory concentration MIC with eye.Other three kinds of antibiotic are recorded as penicillin, ampicillin, Ciprofloxacin minimal inhibitory concentration MIC with method.
(3) mensuration of MBC (MBC) draws each hole culture that more than 0.1mL said medicine minimal inhibitory concentration has no bacterial growth respectively, move on the plate agar medium of not pastille, culture is pushed open gently with aseptic " L " type glass bar, put overnight incubation in 37 DEG C of incubators, observation has asepsis growth, and counting is less than the MBC MBC that 5 bacterium colony persons are this medicine.Other three kinds of antibiotic are recorded as penicillin, ampicillin, Ciprofloxacin MBC MBC with method.
The crude drug extract medicament sensitivity test of this Chinese herbal feed additive the results are shown in Table 1, the crude drug extract of this Chinese herbal feed additive to MIC, MBC result of the test of staphylococcus aureus and Streptococcusagalactiae in table 2.
This Chinese herbal feed additive of table 1 is to the drug sensitive test result mm of two kinds of bacterium
Medicine Staphylococcus aureus Streptococcusagalactiae
Penicillin 21.80±2.00 19.80±1.80
Ampicillin 20.70±1.20 22.40±1.80
Ciprofloxacin 20.20±1.50 18.80±1.40
The crude drug extract of this feed addictive 23.90±1.80 24.30±1.70
Table 1 shows, and to staphylococcus aureus, the crude drug extract of this Chinese herbal feed additive is extremely quick, and bacteriostatic diameter reaches 23.90mm, and penicillin, ampicillin and Ciprofloxacin are Gao Min; To Streptococcusagalactiae, the crude drug extract of this Chinese herbal feed additive is extremely quick, and bacteriostatic diameter reaches 24.30mm, and other medicines such as penicillin, ampicillin and Ciprofloxacin are Gao Min.
This Chinese herbal feed additive of table 2 is to MIC, MBC result of the test g/mL of two kinds of bacterium
Table 2 shows, the crude drug extract of this Chinese herbal feed additive to the suppression of staphylococcus aureus and Streptococcusagalactiae and killing action stronger, the minimum suppression of staphylococcus aureus (MIC) and kill (MBC) concentration and can reach 0.008g/mL, 0.016g/mL respectively, the minimum suppression of Streptococcusagalactiae (MIC) and kill (MBC) concentration 0.004g/mL.Other medicines such as penicillin, ampicillin and Ciprofloxacin take second place.
Drug sensitivity test shows, staphylococcus aureus and the crude drug extract of Streptococcusagalactiae to this Chinese herbal feed additive the most responsive; Ampicillin takes second place; The crude drug extract of this Chinese herbal feed additive to the suppression of staphylococcus aureus and Streptococcusagalactiae and killing action comparatively strong, ampicillin takes second place.Comparatively the antibiotic such as penicillin is good to the inhibition of cow subclinical mastitis 2 kinds of pathogens for the crude drug extract of this Chinese herbal feed additive, should as first-selection in the practice of control cow subclinical mastitis.
2, this Chinese herbal feed additive is on the impact of milk cow production performance
32 He Sitan lactating cows, are divided into 4 groups at random by test requirements document, often organize 8, feed respectively in fine fodder, add the daily ration of 0.2%, 0.4%, 0.6% Chinese herbal feed additive, and test schedules to last 60d.Result shows: in feed add 0.2%, 0.4%, 0.6% feed addictive examination ox comparatively control group improve the output of milk reach 4.02%, 12.5%, 14.0% (P>0.05) respectively, impact is not determined on milk nutritive index (butterfat, lactoprotein, lactose, total milk solid), but significantly can reduce somatic number.This Chinese herbal feed additive affects experimental design scheme in table 3 to milk cow production performance, and each test group milk production of cow statistics is in table 4, and each test group milk quality refers to that measurement result is in table 5, and each group concentrated feed and roughage consumption are in table 6.
Table 3 experimental design scheme
Group Design
Test 1 group This feed addictive of basal diet+0.2%
Test 2 groups This feed addictive of basal diet+0.4%
Test 3 groups This feed addictive of basal diet+0.6%
Control group Basal diet
Table 4 each test group milk production of cow statistical form unit: kg, %
Group The individual average daily output of milk in experimental period Comparatively control group increases the output of milk Increase percentage
Test 1 group 20.43±1.08 a 0.79 4.02
Test 2 groups 22.10±0.89 b 2.64 12.5
Test 3 groups 22.39±1.02 b 2.75 14.0
Control group 19.64±0.95 a
Note: same column lowercase identical table differential is different not remarkable, and same column lowercase difference represents significant difference, and capitalization difference represents that difference is extremely remarkable.Lower same.
Table 4 shows, and tests average daily individual milk yield in 1,2,3 group and control group experimental period and is respectively 20.43 ± 1.08kg, 22.10 ± 0.89kg, 22.39 ± 1.02kg and 19.64 ± 0.95kg.In trial stretch, with the increase of this Chinese herbal medicine powder addition in daily ration, milk crop is increase trend; Test 2,3 groups of average daily outputs of milk and be significantly higher than control group and test 1 group (P<0.05), test difference between 1 group and control group and not significantly (P>0.05), test the comparatively control group raising 4.02%, 12.5%, 14.0% respectively of 1,2 and 3 group of average daily output of milk.
Table 5 feed addictive of the present invention affects unit to the every quality index of milk: %
Group Butter oil Lactoprotein Total solid
Test 1 group 3.16±0.32 a 2.93±0.09 a 8.19±0.16
Test 2 groups 3.34±0.21 a 2.95±0.02 a 8.18±0.25
Test 3 groups 3.49±0.12 a 2.94±0.05 a 8.21±0.33
Control group 3.12±0.25 a 2.92±0.03 a 8.14±0.12
GB19645-2005 ≥3.1 ≥2.9 ≥8.1
Table 5 shows, butter oil, lactoprotein, total solid etc. that each test group early stage, mid-term and later stage three sampling measure, every quality index all meets pasteurize, sterile milk state health standards (GB19645-2005), with the increase of this Chinese herbal feed additive addition, milk butterfat percnetage has increase trend, and (difference is not remarkable, P>0.05), between each group content of milk protein and total solid basically identical.The full phase is respectively organized concentrated feed consumption and reduces with the increase of this Chinese herbal feed additive addition, control group is significantly higher than test 1,2 groups (P<0.05), pole is significantly higher than test 3 groups (P<0.01), test 1,2,3 group and often consume 1kg concentrate supplement, the average daily individual milk yield of milk cow comparatively control group improves 0.24kg, 0.31kg and 0.60kg.The full phase is respectively organized roughage consumption and also has the trend reduced with the increase of this Chinese herbal feed additive addition, test 2,3 groups of roughages to consume significantly lower than control group (P<0.05), pole is markedly inferior to test 1 group (P<0.01).
Table 6 is group feed consumption statistical form unit respectively: kg
Table 6 shows, test 1,2 and 3 group of average daily individual milk yield respectively comparatively control group improve 0.79kg, 2.64kg and 2.75kg, the average daily output value increasing by 2.37 yuan, 7.92 yuan and 8.25 yuan compared with control group, annual (calculating by 305d) increases the income of 722.80 yuan, 2415.60 yuan and 2516.30 yuan respectively compared with control group; Test 1,2,3 group of head equal day feed cost comparatively many inputs of control group-0.25 yuan ,-0.47 yuan and-0.67 yuan, each group of every sun adds this Chinese herbal feed additive cost and is respectively 0.31 yuan, 0.62 yuan and 0.93 yuan, and annual (calculating by 305d) is used compared with the feed cost of control group saving-18.30 yuan ,-45.75 yuan and-79.30 yuan respectively; Two add up to test 1,2,3 groups comparatively increase newly in control group head equal year income 704.50 yuan, 2369.85 yuan and 2437.00 yuan.
1,2,3 test group of this Chinese herbal feed additive adds this Chinese herbal feed additive of 0.2%, 0.4%, 0.6% respectively, and the average daily output of milk of milk cow is comparatively control group improve 4.02%, 12.5%, 14.0% respectively; The quality index such as each group of butter oil, lactoprotein, non-fat solid content meet pasteurize, sterile milk state health standards (GB 19645-2005); And with the increase of this Chinese herbal feed additive addition, milk butterfat percnetage has increase trend; Lactoprotein, non-fat solid content are basically identical.The full phase is respectively organized concentrated feed consumption and reduces with the increase of this Chinese herbal feed additive addition, tests 1,2,3 group and often consumes 1kg concentrate supplement, and the average daily individual milk yield of milk cow comparatively control group increases 0.19kg, 0.38kg and 0.51kg.Experimental result shows, the Chinese herbal feed additive of this treatment mastitis for milk cows has specific disease-prevention health effect, to control mastitis for milk cows there is certain effect.

Claims (2)

1. treat a Chinese herbal feed additive for mastitis for milk cows, it is characterized in that it is the medicament be made up of the raw material of following weight parts: cordate houttuynia 5 parts-7 parts, brook anemone 4 parts-6 parts, play both sides of the street 4 parts-6 parts, luffa 3 parts-5 parts, the seed of cowherb 3 parts-5 parts, the radix paeoniae rubrathe 2 parts-4 parts, radix scrophulariae 2 parts-4 parts, frankincense 2 parts-4 parts, myrrh 2 parts-4 parts, Echinacea 2 parts-4 parts, the Radix Astragali 2 parts-4 parts, 1 part-2 parts, Radix Glycyrrhizae.
2. the Chinese herbal feed additive for the treatment of mastitis for milk cows according to claim 1, is characterized in that it is the medicament be made up of the raw material of following weight parts: cordate houttuynia 7 parts, brook anemone 6 parts, play both sides of the street 6 parts, luffa 4 parts, the seed of cowherb 4 parts, the radix paeoniae rubrathe 2 parts, radix scrophulariae 2 parts, frankincense 2 parts, myrrh 2 parts, Echinacea 2 parts, the Radix Astragali 2 parts, 1 part, Radix Glycyrrhizae.
CN201510019502.3A 2015-01-15 2015-01-15 Chinese traditional herb feed additive for treating cow mastitis Pending CN104489279A (en)

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Cited By (4)

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CN105920234A (en) * 2016-05-30 2016-09-07 青岛海之源智能技术有限公司 Feed additive for preventing and treating female mink mastitis and preparation method thereof
CN106551089A (en) * 2015-09-21 2017-04-05 刘吴阳 A kind of armour-piercing stimulating milk secretion feed additive
CN108813172A (en) * 2018-06-20 2018-11-16 濮阳市天然林牧业科技开发有限公司 A kind of cow feed additive
IT202000018970A1 (en) 2020-08-03 2022-02-03 Asoltech Srl MYRRH-BASED COMPOSITION

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CN101612335A (en) * 2009-07-22 2009-12-30 天津生机集团股份有限公司 Be used to Chinese medicine composition of preventing and treating mammitis of cow and preparation method thereof
CN102669482A (en) * 2012-06-09 2012-09-19 河南中医学院 Chinese herbal medicine feed additive for preventing cow recessive mastitis
CN102940719A (en) * 2012-09-05 2013-02-27 河北科技师范学院 Chinese herbal medicine feed additive for treating dairy cow mastitis
CN103751509A (en) * 2014-01-13 2014-04-30 黑龙江八一农垦大学 Chinese herbal medicine composition for treating clinical mastitis

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CN101612335A (en) * 2009-07-22 2009-12-30 天津生机集团股份有限公司 Be used to Chinese medicine composition of preventing and treating mammitis of cow and preparation method thereof
CN102669482A (en) * 2012-06-09 2012-09-19 河南中医学院 Chinese herbal medicine feed additive for preventing cow recessive mastitis
CN102940719A (en) * 2012-09-05 2013-02-27 河北科技师范学院 Chinese herbal medicine feed additive for treating dairy cow mastitis
CN103751509A (en) * 2014-01-13 2014-04-30 黑龙江八一农垦大学 Chinese herbal medicine composition for treating clinical mastitis

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106551089A (en) * 2015-09-21 2017-04-05 刘吴阳 A kind of armour-piercing stimulating milk secretion feed additive
CN105920234A (en) * 2016-05-30 2016-09-07 青岛海之源智能技术有限公司 Feed additive for preventing and treating female mink mastitis and preparation method thereof
CN108813172A (en) * 2018-06-20 2018-11-16 濮阳市天然林牧业科技开发有限公司 A kind of cow feed additive
IT202000018970A1 (en) 2020-08-03 2022-02-03 Asoltech Srl MYRRH-BASED COMPOSITION
WO2022029067A1 (en) 2020-08-03 2022-02-10 Asoltech S.R.L. Composition based on myrrh

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Application publication date: 20150408