CN102349895B - 一种注射用西咪替丁组合物及其制备方法 - Google Patents
一种注射用西咪替丁组合物及其制备方法 Download PDFInfo
- Publication number
- CN102349895B CN102349895B CN 201110299598 CN201110299598A CN102349895B CN 102349895 B CN102349895 B CN 102349895B CN 201110299598 CN201110299598 CN 201110299598 CN 201110299598 A CN201110299598 A CN 201110299598A CN 102349895 B CN102349895 B CN 102349895B
- Authority
- CN
- China
- Prior art keywords
- cimetidine
- injection
- citric acid
- stirring
- dissolving
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
西咪替丁 | 10%盐酸用量 | 10%枸橼酸用量 | 溶液最终pH值 | 药液含量 |
4.0 | 2.9 | 0 | 5.75 | 89.1 |
4.0 | 0 | 13.05 | 5.75 | 99.7 |
4.0 | 适量 | 5.00 | 5.75 | 99.5 |
4.0 | 适量 | 2.00 | 5.75 | 99.8 |
4.0 | 适量 | 1.50 | 5.75 | 92.3 |
本发明注射用西咪替丁组合物 | 西咪替丁注射液 | |
0月 | 0.29% | 0.34 |
3月 | 0.30 | 0.36 |
6月 | 0.29 | 0.43 |
9月 | 0.31 | 0.47 |
12月 | 0.33 | 0.55 |
18月 | 0.36 | 0.66 |
24月 | 0.40 | 0.79 |
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 201110299598 CN102349895B (zh) | 2011-09-28 | 2011-09-28 | 一种注射用西咪替丁组合物及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 201110299598 CN102349895B (zh) | 2011-09-28 | 2011-09-28 | 一种注射用西咪替丁组合物及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102349895A CN102349895A (zh) | 2012-02-15 |
CN102349895B true CN102349895B (zh) | 2013-04-10 |
Family
ID=45573614
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 201110299598 Active CN102349895B (zh) | 2011-09-28 | 2011-09-28 | 一种注射用西咪替丁组合物及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN102349895B (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102670496A (zh) * | 2012-05-25 | 2012-09-19 | 鼎正动物药业(天津)有限公司 | 一种西咪替丁注射液及其制备方法 |
CN110496099B (zh) | 2013-09-11 | 2022-06-21 | 伊戈尔生物药品股份有限公司 | 包含粘度降低剂的液体蛋白质制剂 |
CN106943358B (zh) * | 2016-01-06 | 2021-08-31 | 河南省肿瘤医院 | 福沙匹坦二甲葡胺冻干粉针及其制备方法 |
CN112353799A (zh) * | 2021-01-06 | 2021-02-12 | 福安药业集团湖北人民制药有限公司 | 一种注射用西咪替丁组合物及其制备方法与应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1596893A (zh) * | 2004-07-29 | 2005-03-23 | 沈阳药科大学 | 注射用西眯替丁冻干制剂及其制备方法 |
CN1823768A (zh) * | 2006-01-09 | 2006-08-30 | 徐新盛 | 西咪替丁冻干组合物 |
-
2011
- 2011-09-28 CN CN 201110299598 patent/CN102349895B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1596893A (zh) * | 2004-07-29 | 2005-03-23 | 沈阳药科大学 | 注射用西眯替丁冻干制剂及其制备方法 |
CN1823768A (zh) * | 2006-01-09 | 2006-08-30 | 徐新盛 | 西咪替丁冻干组合物 |
Also Published As
Publication number | Publication date |
---|---|
CN102349895A (zh) | 2012-02-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102349895B (zh) | 一种注射用西咪替丁组合物及其制备方法 | |
CA3157550C (en) | Injectable psychoactive alkaloid composition and preparation thereof | |
CN103054863B (zh) | 一种奥美拉唑钠的药物组合物及其制备方法 | |
CN102058593A (zh) | 艾普拉唑钠的组合药物及其制备工艺 | |
CN102525963B (zh) | 一种硫酸奈替米星冻干粉针及其制备方法 | |
CN102285970B (zh) | 一种埃索美拉唑化合物、制备方法及其药物组合物 | |
CN102276533B (zh) | 一种新的奥扎格雷钠化合物及其药物组合物 | |
CN101693014B (zh) | 一种辅酶a药物冻干制剂的制备方法 | |
CN103214382B (zh) | 一种盐酸甲氯芬酯化合物及其药物组合物 | |
CN102973524A (zh) | 一种埃索美拉唑钠冻干粉针剂及其制备方法 | |
CN102488712A (zh) | 一种人工牛黄包合物、其制备方法及其应用 | |
CN102018677A (zh) | 注射用盐酸罗沙替丁醋酸酯及其制备方法 | |
CN103330688A (zh) | 治疗胃病的雷尼替丁冻干粉针剂 | |
CN103113390B (zh) | 一种舒巴坦钠化合物及其与美洛西林钠的药物组合物 | |
CN103417568B (zh) | 甘油果糖氯化钠注射液的制备方法 | |
CN102367229A (zh) | 一种二乙酰氨乙酸乙二胺化合物及其药物组合物 | |
CA3103707C (en) | Standardized psychoactive alkaloid extract composition | |
CN105125507B (zh) | 一种埃索美拉唑钠注射用冻干粉组合物及其制备方法 | |
CN101815443A (zh) | 片剂或胶囊剂食品 | |
CN104884066B (zh) | 含有壳寡糖的淀粉酶活性抑制用组合物 | |
CN112353799A (zh) | 一种注射用西咪替丁组合物及其制备方法与应用 | |
CN103462909B (zh) | 一种注射用尼扎替丁制剂 | |
CN105476954A (zh) | 一种盐酸洛美沙星注射剂及制备方法 | |
CN103315986B (zh) | 一种可溶且稳定的帕托珠利组合物及其制备方法 | |
CN101693015B (zh) | 一种辅酶a药物冻干制剂及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee |
Owner name: HAINAN XIANTONG PHARMACEUTICAL CO., LTD. Free format text: FORMER NAME: HAINAN LIANGFANG MEDICINE CO., LTD. |
|
CP01 | Change in the name or title of a patent holder |
Address after: 100012 Beijing city Chaoyang District Beiyuan No. 5 District four building three layer Research Institute Patentee after: HAINAN XIANTONG PHARMACEUTICAL CO., LTD. Address before: 100012 Beijing city Chaoyang District Beiyuan No. 5 District four building three layer Research Institute Patentee before: Hainan Liangfang Medicine Co., Ltd. |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20151207 Address after: Three cross road 570311 in Hainan province Haikou City, national hi tech Industrial Development Zone No. 8 trough Patentee after: Hainan Huanglong Pharmaceutical Co., Ltd. Address before: 100012 Beijing city Chaoyang District Beiyuan No. 5 District four building three layer Research Institute Patentee before: HAINAN XIANTONG PHARMACEUTICAL CO., LTD. |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Cimetidine composition for injection and preparation method thereof Effective date of registration: 20181019 Granted publication date: 20130410 Pledgee: Bank of China Limited by Share Ltd Haikou Dragon Ball branch Pledgor: Hainan Huanglong Pharmaceutical Co., Ltd. Registration number: 2018460000009 |