CN102293224A - Pharmaceutical composition for killing termite - Google Patents

Pharmaceutical composition for killing termite Download PDF

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Publication number
CN102293224A
CN102293224A CN2011101961290A CN201110196129A CN102293224A CN 102293224 A CN102293224 A CN 102293224A CN 2011101961290 A CN2011101961290 A CN 2011101961290A CN 201110196129 A CN201110196129 A CN 201110196129A CN 102293224 A CN102293224 A CN 102293224A
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termite
pharmaceutical composition
killing
monkshood
composition
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丁绍兴
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Beihai Control Office Of Termite
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Beihai Control Office Of Termite
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Abstract

The invention discloses a pharmaceutical composition for killing termites. A termite is a very harmful insect and poses severe harm and great economic loss to a variety of departments and fields of national economy. Conventional termite insecticides are prepared from chemical agents with great toxicity, pose severe pollution to environment and can not thoroughly kill termites at bottom. According to the invention, Aconitum kusnezoffii, monkshood, realgar, pinellia ternate, hydnocarpus seeds, semen torreya, capsicum and talcum powder are used as raw materials; the composition can be prepared into a plurality dosage forms like pulvis, granules and tablets, and has the characteristics of safety, nontoxicity, fast action, thorough killing of termites, etc. The medicine source for the composition is abundant; a preparation method for the composition is simple and practicable, and enables low cost to be realized.

Description

A kind of pharmaceutical composition of killing termite
Technical field
The present invention relates to a kind of pharmaceutical composition of killing termite, particularly a kind of pharmaceutical composition of being made up of Chinese medicine of killing termite belongs to the medicine chemical field.
Background technology
Termite is the very large insect of a kind of harmfulness, in China various places distribution is arranged all, especially is the torrid zone, subtropical zone, endangers the most serious.Termite damages all kinds of building constructions, agricultural, storage goods and materials, water conservancy projects, electric power facility, and serious harm and heavy economic losses have all been caused in a plurality of departments of national economy, field.Because termite damage extensively and seriously, so people are seeking various medicine and the methods of killing termite safely and effectively all the time.
China's tradition is killed termite and is mainly used Niran, two kinds of chemical agents of mirex.The effect of these two kinds of chemical agent control termites is very good; but; they belong to persistence organic pollutant (being called for short POPS); not only people and animal had high toxicity; and be difficult under field conditions (factors) degrade; can be from the local influence to the zone and even global environment by biological concentration characteristic and boiling characteristics, in order to protect human health and ecological environment security, China has forbidden producing, use and circulating to these two kinds of chemical agents.Therefore, under this historical background, demand urgently seeking and a kind ofly can substitute Niran and mirex and the termite control novel drugs of the environmental type human, that natural environment is friendly.The white-ant drug of killing of at present researching and developing or using has chemicals, fungi, heavy metal, hormone etc., publication number is the patent of invention of CN101189973A, a kind of Chinese medicine of killing white ant is disclosed, be mixed and made into Rhododendron molle, bitter real, detailed golden flower, black false hellebore, kuh-seng, corydalis tuber, Biphenthrin and corn flour, talcum powder, but the Chinese medicine of this killing white ant is not pure Chinese medicine to be made, its Biphenthrin that contains is a kind of poisonous chemicals, can affect to environment.Further retrieval again finds no the white-ant drug composition technology of the killing disclosure that pure Chinese medicine is formed, so a kind of pharmaceutical composition of being made up of Chinese medicine of killing termite is highly significant for killing termite.
Summary of the invention
The purpose of this invention is to provide a kind of pharmaceutical composition of killing termite, the pharmaceutical composition of being made up of pure Chinese medicine of killing termite especially in order to killing termite, and makes termite be stained with to infect mutually behind the medicinal powder and causes death.Overcoming tradition, to kill white-ant drug toxicity big, difficult degradation, and high pollution destroys the deficiency of environment.
For achieving the above object, the present invention has taked such measure, and a kind of pharmaceutical composition of killing termite mainly is prepared from according to a conventional method by the following weight parts raw material:
Radix aconiti agrestis 3-40 part monkshood 5-50 part realgar 10-60 part
Tuber of pinellia 6-40 part chaulmoogra 2-25 part Chinese torreyanut 2-30 part
Capsicum 1-20 part talcum powder 30-60 part
Preparing preferred weight part ratio range of the present invention is:
Radix aconiti agrestis 10-20 part monkshood 20-30 part realgar 20-40 part
Tuber of pinellia 10-20 part chaulmoogra 5-15 part Chinese torreyanut 5-20 part
Capsicum 5-15 part talcum powder 20-40 part
Described raw material all is " medicines that Chinese pharmacopoeia is recorded.
Aforementioned pharmaceutical compositions can be prepared into pulvis, granule and tablet.
Aforementioned pharmaceutical compositions is prepared into pulvis by following method:
(1) gets radix aconiti agrestis, monkshood, realgar, the tuber of pinellia, chaulmoogra, Chinese torreyanut, capsicum and remove impurity through screening respectively;
(2) each Chinese medicine material that will remove behind the impurity is pulverized with powder beater respectively;
(3) each Chinese medicine material after will pulverizing is crossed 80 mesh sieves respectively and is obtained 80 order fine powders;
(4) each the Chinese medicine material fine powder that will handle through sieving adds talcum powder, mixes in described ratio;
(5) raw material that mixes is crossed 80 mesh sieves, check packs.
Take the present invention of above-mentioned measure, the radix aconiti agrestis in raw materials used is the piece root of the Ranunculaceae herbaceos perennial rhizome of Chinese monkshood (wild species) or the northern rhizome of Chinese monkshood.The piece root of the north rhizome of Chinese monkshood contains total alkaloids 0.70~1.3%.It is 0.82~1.56% that the piece root of the rhizome of Chinese monkshood contains total alkaloids.The north rhizome of Chinese monkshood and the rhizome of Chinese monkshood all contain the di esters alkaloid of severe toxicity, respiratory center, vasomotor center and the reflection function of people and other animal are all had the paralysis effect, so termite is had stronger toxic action.Main component of monkshood and effect and radix aconiti agrestis basic identical.Tuber of pinellia stem tuber contains volatile oil, nicotine, the pharmacological action number of chemical compositions such as alkaloid similar to coniine and nicotine.The tuber of pinellia all can cause intense stimulus to oral cavity, larynx, the gastrointestinal mucosal of people and other animal, serious also can cause total numbness, oligopnea and whole, spasm, expiratory dyspnea, at last paralysis and dead.So the tuber of pinellia also has stronger toxic action to termite.The realgar chemical composition is arsenones AsS, is the detoxifcation insecticidal materials that passes for a long time among the people.The chaulmoogra nature and flavor are pungent, and are poisonous, and the effect of controlling worm is arranged.Chinese torreyanut is the dry mature seed of taxaceae plant Chinese torreya, has the effect of antiparasitic etc.The capsicum nature and flavor are pungent, can strengthen the effect of their killing white ant with other material medicine of the present invention.The talcum powder lubricity is good, in the present invention as filler, makes medicine be easy in use spray.
The present invention is applicable to that the place that ant suffers from takes place for family, warehouse, boats and ships, fruit-bearing forest, reservoir dam, lawn etc.Use when of the present invention, adopt the method that sprays to carry out dispenser in place that termite activity is arranged or ant road, in the ant nest, consumption is 5 to 8 grams; Spraying in luring case then consumption be 10 to 15 grams, spray to lure and can lure a large amount of termites to make it to infect mutually to cause death in the case.This is because termite has mutual feeding, licks and lick the other side and eat up dead termite to keep the clean habit of nest, so medicinal powder can infect between colony.
Having taked the present invention of above-mentioned measure, is to be made by pure Chinese medicine, thereby it is wide to have a medicine source, and cost is low, the production technology characteristic of simple, and do not contain chemicals, easily degraded is free from environmental pollution.The present invention makes with Chinese medicine, toxicity than chemicals make to kill the termite medicine low, termite can be dead immediately after being infected with medicinal powder, infects mutually with other termites but get back in the nest, so just improve the quantity of killing termite, can play the effect of radical cure termite.At these characteristics of the present invention, carried out following test:
1 test material
1.1 for examination termite kind
Taiwan formosanes Coptotermes formosanus Shiraki
1.2 reagent agent
Chinese medicine powder of the present invention, fluorine worm nitrile (content: 0.5%)
2 test methods
Take by weighing the dried fine sand of 100 grams and put into the matrix of the culture dish of 9 centimetres of diameters as the cultivation termite, it is moistening a little by fine sand to spray pure water.150 active Taiwan formosanes worker ants of health are put into a culture dish that spreads Chinese medicine termite control pulvis, treat that termite all speckles with behind the medicinal powder on one's body termite to be moved in 3 culture dishes that are covered with fine sand (promptly establishing 3 repetitions) 50 in every ware.Other gets 50 healthy Taiwan formosanes worker ants of not being stained with medicinal powder and puts into another culture dish that is covered with fine sand as blank.It is edible for termite all to put into the clean moistening newspaper of a little group in each ware.The death condition of termite in the every ware of observed and recorded regularly, and dead termite chosen.
3 result of the tests
3.1 lethal time to the Taiwan formosanes
As can be seen from Table 1, the drug effect of fluorine worm nitrile (contrast) is very fast, handles back quantity of knocking down termite in 19 hours and has reached 95%.And the Kt of Chinese medicine powder of the present invention 50, Kt 75, Kt 95Be respectively 35 hours, 60 hours and 81 hours.Comparatively speaking, Chinese medicine powder drug effect of the present invention relatively relaxes, and can guarantee that termite is stained with can also get back to behind this pulvis in the nest other termite infected to cause death.
Table 1 test medicine is to the lethal time of Taiwan formosanes
Figure BSA00000537753800041
3.2 lethality day by day to the Taiwan formosanes
Add up the day by day lethality of Chinese medicine powder of the present invention to the Taiwan formosanes, Chinese medicine powder of the present invention in test promptly begins to show at the 1st day to the toxic action of Taiwan formosanes, and termite begins to occur dead.Dead peak promptly occurred at the 2nd day, the highest lethality day by day is 55.3%.After the dead peak, As time goes on, termite continues dead, and is all dead to the 6th day termite.This result of the test shows, Chinese medicine powder of the present invention acts on poisonous the killing of termite, and termite does not have death immediately after contacting this medicament, but after after a while, just begin to die off, this has illustrated also that termite speckles with can also return behind the pulvis of the present invention in the nest other termite infected on one's body and has caused death.
Embodiment
Embodiment 1
1. fill a prescription: radix aconiti agrestis 30g monkshood 50g realgar 100g
Tuber of pinellia 60g chaulmoogra 20g Chinese torreyanut 20g
Capsicum 10g talcum powder 300g
2. preparation method:
(1) get radix aconiti agrestis 30g, monkshood 50g, realgar 100g, tuber of pinellia 60g, chaulmoogra 20g, Chinese torreyanut 20g, capsicum 10g screens respectively and removes impurity;
(2) each Chinese medicine material that will remove behind the impurity is pulverized with powder beater respectively;
(3) each Chinese medicine material after will pulverizing is crossed 80 mesh sieves respectively and is obtained 80 order fine powders;
(4) each the Chinese medicine material fine powder that will handle through sieving adds talcum powder 300g, mixes in described ratio;
(5) raw material that mixes is crossed 80 mesh sieves, check packs.
Below be the result of the test of embodiment 1:
Figure BSA00000537753800051
Figure BSA00000537753800061
Embodiment 2
1. fill a prescription: radix aconiti agrestis 40g monkshood 50g realgar 60g
Tuber of pinellia 40g chaulmoogra 25g Chinese torreyanut 30g
Capsicum 20g talcum powder 60g
2. preparation method:
(1) get radix aconiti agrestis 40g, monkshood 50g, realgar 60g, tuber of pinellia 40g, chaulmoogra 25g, Chinese torreyanut 30g, capsicum 20g screens respectively and removes impurity;
(2) each Chinese medicine material that will remove behind the impurity is pulverized with powder beater respectively;
(3) each Chinese medicine material after will pulverizing is crossed 80 mesh sieves respectively and is obtained 80 order fine powders;
(4) each the Chinese medicine material fine powder that will handle through sieving adds talcum powder 60g, mixes in described ratio;
(5) raw material that mixes is crossed 80 mesh sieves, check packs.
Below be the result of the test of embodiment 2:
Figure BSA00000537753800071
Figure BSA00000537753800081
Embodiment 3
1. fill a prescription: radix aconiti agrestis 100g monkshood 200g realgar 200g
Tuber of pinellia 100g chaulmoogra 50g Chinese torreyanut 50g
Capsicum 50g talcum powder 200g
2. preparation method:
(1) getting radix aconiti agrestis 50g, monkshood 150g, realgar 200g, tuber of pinellia 70g, chaulmoogra 30g, Chinese torreyanut 30g, capsicum 30g, to be prepared into medicinal powder according to the preparation method of embodiment 1 standby;
(2) get radix aconiti agrestis 50g, monkshood 50g, realgar 50g, tuber of pinellia 30g, chaulmoogra 20g, Chinese torreyanut 20g, capsicum 20g routinely leach extraction method make relative density and be about 1.05 Chinese medicine extract;
(3) in the Chinese medicine extract that the medicinal powder adding step (2) that step (1) is made makes, make the thick paste that relative density is 1.20-1.35 according to a conventional method;
(4) thick paste is made softwood, be prepared into particle according to a conventional method, with the particle 80-100 ℃ drying that makes, dried particle and talcum powder mix, packing, and sealing, promptly.
(5) or with above-mentioned dried particle be pressed into tablet through tablet press machine.

Claims (3)

1. pharmaceutical composition of killing termite is characterized in that described pharmaceutical composition is prepared from according to a conventional method by the following weight parts raw material:
Radix aconiti agrestis 3-40 part monkshood 5-50 part realgar 10-60 part
Tuber of pinellia 6-40 part chaulmoogra 2-25 part Chinese torreyanut 2-30 part
Capsicum 1-20 part talcum powder 30-60 part
2. the pharmaceutical composition of killing termite according to claim 1 is characterized in that described pharmaceutical composition is made up of following preferred weight part raw material:
Radix aconiti agrestis 10-20 part monkshood 20-30 part realgar 20-40 part
Tuber of pinellia 10-20 part chaulmoogra 5-15 part Chinese torreyanut 5-20 part
Capsicum 5-15 part talcum powder 20-40 part
3. the pharmaceutical composition of killing termite according to claim 1 and 2 is characterized in that described preparation of pharmaceutical compositions becomes pulvis, granule or tablet.
CN2011101961290A 2011-07-12 2011-07-12 Pharmaceutical composition for killing termite Pending CN102293224A (en)

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Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102578166A (en) * 2011-12-30 2012-07-18 北海市白蚁防治所 Chinese medicinal bait for killing ants and cockroaches
CN102939999A (en) * 2012-11-27 2013-02-27 北海市白蚁防治所 Attractant for killing termites
CN103609617A (en) * 2013-11-25 2014-03-05 北海市白蚁防治所 Chinese medicine type termite biocide and preparation method thereof
CN103975964A (en) * 2014-05-30 2014-08-13 江德全 Chinese herbal bait
CN104757037A (en) * 2014-06-03 2015-07-08 张春华 Spicy allicin non-toxic insecticide and preparation method thereof
CN104761196A (en) * 2015-03-16 2015-07-08 陈炳新 Grave protective material
CN105028523A (en) * 2015-07-23 2015-11-11 柳州博泽科技有限公司 Traditional Chinese medicine type ant attractant prepared through water extraction and preparation method thereof
CN105028517A (en) * 2015-04-06 2015-11-11 韩城市秦龙花椒科技有限责任公司 Processing method of traditional Chinese medicine plant composite-insecticidal pollution-free pesticide powder
CN105053065A (en) * 2015-07-23 2015-11-18 柳州博泽科技有限公司 Traditional Chinese medicine ant attractive toxicant prepared by alcohol extraction and preparation method for traditional Chinese medicine ant attractive toxicant prepared by alcohol extraction
CN105145672A (en) * 2015-07-23 2015-12-16 柳州博泽科技有限公司 Traditional Chinese medicine ant attractant and preparation method therefor
CN105794887A (en) * 2016-04-18 2016-07-27 旌德县隐龙梅园生态农场 Chemical for preventing and controlling prune tree termites and preparation method thereof
CN105994431A (en) * 2016-06-23 2016-10-12 重庆大学 Efficient and lasting termite control preparation and preparation method thereof
CN106088367A (en) * 2016-06-23 2016-11-09 重庆大学 Ancient building termite control treatments
CN107372654A (en) * 2017-08-11 2017-11-24 句容市森林白蚁防治研究所 A kind of termiticide fumicants and its application
CN107410387A (en) * 2017-07-27 2017-12-01 毕晓峰 A kind of Chinese herbal medicine type termite-killing trapping gluing bait formulation, glued bait formulation plate and preparation method thereof
CN115152805A (en) * 2022-04-15 2022-10-11 广东省科学院动物研究所 Synergistic Chinese medicine termite killing agent for effectively repelling and preventing termites and application thereof

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Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102578166A (en) * 2011-12-30 2012-07-18 北海市白蚁防治所 Chinese medicinal bait for killing ants and cockroaches
CN102939999A (en) * 2012-11-27 2013-02-27 北海市白蚁防治所 Attractant for killing termites
CN102939999B (en) * 2012-11-27 2013-11-20 北海市白蚁防治所 Attractant for killing termites
CN103609617A (en) * 2013-11-25 2014-03-05 北海市白蚁防治所 Chinese medicine type termite biocide and preparation method thereof
CN103975964A (en) * 2014-05-30 2014-08-13 江德全 Chinese herbal bait
CN104757037A (en) * 2014-06-03 2015-07-08 张春华 Spicy allicin non-toxic insecticide and preparation method thereof
CN104761196A (en) * 2015-03-16 2015-07-08 陈炳新 Grave protective material
CN105028517A (en) * 2015-04-06 2015-11-11 韩城市秦龙花椒科技有限责任公司 Processing method of traditional Chinese medicine plant composite-insecticidal pollution-free pesticide powder
CN105028523A (en) * 2015-07-23 2015-11-11 柳州博泽科技有限公司 Traditional Chinese medicine type ant attractant prepared through water extraction and preparation method thereof
CN105053065A (en) * 2015-07-23 2015-11-18 柳州博泽科技有限公司 Traditional Chinese medicine ant attractive toxicant prepared by alcohol extraction and preparation method for traditional Chinese medicine ant attractive toxicant prepared by alcohol extraction
CN105145672A (en) * 2015-07-23 2015-12-16 柳州博泽科技有限公司 Traditional Chinese medicine ant attractant and preparation method therefor
CN105794887A (en) * 2016-04-18 2016-07-27 旌德县隐龙梅园生态农场 Chemical for preventing and controlling prune tree termites and preparation method thereof
CN105994431A (en) * 2016-06-23 2016-10-12 重庆大学 Efficient and lasting termite control preparation and preparation method thereof
CN106088367A (en) * 2016-06-23 2016-11-09 重庆大学 Ancient building termite control treatments
CN106088367B (en) * 2016-06-23 2018-11-06 重庆大学 Ancient building termite control treatments
CN107410387A (en) * 2017-07-27 2017-12-01 毕晓峰 A kind of Chinese herbal medicine type termite-killing trapping gluing bait formulation, glued bait formulation plate and preparation method thereof
CN107372654A (en) * 2017-08-11 2017-11-24 句容市森林白蚁防治研究所 A kind of termiticide fumicants and its application
CN115152805A (en) * 2022-04-15 2022-10-11 广东省科学院动物研究所 Synergistic Chinese medicine termite killing agent for effectively repelling and preventing termites and application thereof

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Application publication date: 20111228