CN102283976A - Drug for treating cancer - Google Patents

Drug for treating cancer Download PDF

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CN102283976A
CN102283976A CN2011102336846A CN201110233684A CN102283976A CN 102283976 A CN102283976 A CN 102283976A CN 2011102336846 A CN2011102336846 A CN 2011102336846A CN 201110233684 A CN201110233684 A CN 201110233684A CN 102283976 A CN102283976 A CN 102283976A
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herba
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cancer
tumor
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CN102283976B (en
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曹春徕
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Abstract

The invention relates to a drug for treating cancer. The drug is prepared from the following raw materials: gamboge, pine pollen, airpotato yam, periostracum serpentis, Japanese coniogramme rhizome, kiwi fruits, Portulaca grandiflora Hook., Herba Lobeliae Chinensis, Hedyotis diffusa, Scorpio, semiaquilegia adoxoides, Solanum nigrum, Arisaema cum bile, blackberry lily, catchweed bedstraw herb, Sedum lineare, plantain, viola japonica, toad, Meloe coarctatus, Calonyction muricatum, Atropa belladonna, selfheal, copperleaf herb, datura flower, yam and licorice. The drug extracts anticancer and tumor-eliminating effective ingredients from traditional Chinese medicines, has the effects of resisting cancer and eliminating tumor, diminishing inflammation and relieving pains as well as repairing organism injury, and has the advantages of low toxic or side effect, low cost and good effect.

Description

A kind of medicine for the treatment of cancer
Technical field
The present invention relates to a kind of medicine for the treatment of cancer.
Background technology
Cancer is the M ﹠ M disease with high.Also be a big disease of harm humans health, its treatment remains a great problem medically.Medical science thinks that cancer is Normocellular improper growth, and the division of cancerous cell and growth are less than restraining, and they can disturb normal cell, forms tumor, and spreads to other position.Current, the treatment cancer excision that adopts commonly used, and cooperate radioactivity and western medicine, operation can only be excised cancer location, but can not eliminate cancerous cell, and radiation and western medicine not only make human organ and normal cell impaired, and radiation and Western medicine cost an arm and a leg, and toxic and side effects is also higher.It is the work of always studying that cancer is treated in utilization Chinese herbal treatment or auxiliary smelting, but present Chinese herbal medicine is controlled cancer also to the bigger toxic and side effects of human body existence, and the cost height, and curative effect can not be satisfactory.
Summary of the invention
The purpose of this invention is to provide a kind of medicine for the treatment of cancer, extract the active ingredient that contains anticancerization tumor from Chinese medicine, have the effect of anticancerization tumor, anti-inflammatory analgetic, reparation body injury, and toxic and side effects is little, cost hangs down good effect.
For this reason, the present invention is the medicine of being made by the following weight proportion raw material:
Figure BSA00000557093100011
The weight proportion of preferred each raw material of the present invention is:
Figure BSA00000557093100012
Figure BSA00000557093100021
The weight proportion of best each raw material of prescription of the present invention is:
Figure BSA00000557093100022
Medicine of the present invention can be made injection, decoct or capsule as required.
Solution of the present invention is according to the rule of the traditional Chinese medical science to the carcinoma disease, i.e. enriching yin and nourishing kidney, and blood circulation promoting and blood stasis dispelling, eliminating stasis to stop pain, the collateral dredging of enriching blood, bactericidal antiphlogistic, clearing away damp-heat rushes down the poison fire, counteracting toxic substances, eliminating stagnation.The present invention forms according to above-mentioned rule, can blood circulation promoting and blood stasis dispelling, and eliminating stasis to stop pain, clearing away damp-heat rushes down the poison fire, and counteracting toxic substances, eliminating stagnation again can eliminating stasis to stop pain, the collateral dredging of enriching blood.
Resina garciniae of the present invention, nature and flavor are sour and astringent, have the counteracting toxic substances detumescence, removing toxic substances, hemostasis, antimicrobial effect.Pollen Pini, nature and flavor are sweet, warm, have the QI invigorating of dispeling the wind, removing dampness, hemostatic effect.Rhizoma Dioscoreae Bulbiferae, nature and flavor hardship, flat has removing heat from blood, pathogenic fire reducing, antidotal effect.Periostracum Serpentis, property sweet-salty, flat, poisonous, have dispel the wind, arresting convulsion, nebula removing, detumescence, parasiticidal effect, can change congestion detoxification heat, the detumescence tumor.Coniogramme japonica (Thunb.) Diels, the little suffering of nature and flavor, cold in nature has expelling wind and clearing away heat, the effect of promoting blood circulation and detoxication.Fructus actinidiae chinensis, nature and flavor acid, cold has analgesicly, quenches the thirst treating stranguria effect.Herba Portulacae Grandiflorae, nature and flavor suffering, cold has heat-clearing and toxic substances removing, the effect of inducing diuresis to remove edema.Herba Lobeliae Chinensis, nature and flavor are sweet, flat, have and relieving asthma, diuretic, repercussive effect.Herba Hedyotidis Diffusae, nature and flavor are sweet, cool, have heat-clearing and toxic substances removing, the effect of diuresis of blood circulation promoting, can stimulate the hypertrophy of reticuloendothelial system, cyton increases, and endochylema is abundant, can obviously strengthen skein cell and leukocytic phagocytic activity, make the defensive rising of human immunity, can effectively play antitumaous effect.Scorpio, the salty suffering of nature and flavor, flat, have dispel the wind, relieving convulsion, collateral dredging, detoxifcation, anticancer antineoplastic action is arranged.Radix Semiaquilegiae, nature and flavor are sweet, cold, have detumescence, detoxifcation, the effect of diuretic.Herba Solani Nigri, nature and flavor hardship, little sweet, cold has heat-clearing and toxic substances removing, eliminating stagnation diuresis, anticancer effect.Arisaema Cum Bile, nature and flavor hardship, cool in nature has the effect of clearing away fire and eliminating phlegm.Rhizoma Belamcandae, nature and flavor hardship, cold has heat-clearing and toxic substances removing, and the blood repercussive effect of loosing has opposing, the effect of antiinflammatory to virus, tumor.Herba Galii Teneri, nature and flavor are arduous, cold, have clearing away damp-heat, and loose and become silted up, detumescence, detoxifcation has antitumor, the effect of cancer.Herba Sedi Linearis, nature and flavor are sweet, cold, have heat clearing away, detumescence, antidotal effect.Herba Plantaginis, nature and flavor are sweet, cold, have diuretic, heat clearing away, the effect that makes eye bright.Herba Violae japonicae, property mildly bitter flavor, cold has heat clearing away, and detoxifcation is controlled toxic swelling, germ-resistant effect.Bufo siccus, nature and flavor suffering, cold have capable water and wet, removing toxic substances, parasite killing, analgesic therapy, to malignant tumor, gastric cancer, bladder cancer, hepatocarcinoma has therapeutical effect.Herba Sonerilae cantonensis, nature and flavor suffering, cold has counteracting toxic substances, pursues the effect of becoming silted up.Herba Solani Surattensis, cold in nature, bitter in the mouth has and dispels the wind, and the effect of exorcising can be treated breast carcinoma ulcer.The purplish or white patches on the skin eggplant, nature and flavor suffering, temperature have the effect of diffusing silt analgesic.Spica Prunellae, nature and flavor suffering, cold has liver heat removing, and the effect of eliminating stagnation cures mainly breast carcinoma, goiter.Herba Acalyphae, nature and flavor bitterness, flat has heat clearing away, diuretic, parasiticidal effect.Flos Daturae, nature and flavor suffering, temperature, the effect of have Dingchuan, dispeling the wind.Rhizoma Dioscoreae, nature and flavor are sweet, flat, have the effect of lung benefiting spleen invigorating.Radix Glycyrrhizae, nature and flavor are sweet, flat, have tonifying the spleen and stomach, QI invigorating, lung moistening, heat clearing away, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription, the main component in the Radix Glycyrrhizae is a glycyrrhizic acid, can strengthen passive protective physical fitness, promotes gastric tissue new life, the glycyrrhizin in the Radix Glycyrrhizae has good Detoxication.
Of the present invention one the course of treatment cost only be 30% of the traditional identical cancer cost course of treatment, can save patient's expense expenditure greatly.
The present invention has eliminating evil just the wound, and set upright and do not stay heresy, the kidney invigorating collateral dredging, warm network blood stasis dispelling, intelligence promoting and the mind tranquilizing, a surname's air to open key, the strongly fragrant eliminating phlegm that looses, subduing swelling and detoxicating, bactericidal antiphlogistic, the collateral dredging of enriching blood has good anticancerization tumor effect.The poison of drug that medical institutions did, pharmacology, effect experiments such as medicine of the present invention Hunan Province Huaihua City hospital prove that it is 90% that animal presses down cancer test effective percentage, and tumour inhibiting rate is 81%, and remission rate is more than 80%.
Animal experiment: select body weight 17~19g Switzerland male mice for use, random packet, 20 every group, every group of average body method of double differences is less than 0.6g.Be divided into experimental group and matched group, the experimental group administration once a day, 52mg/kg, successive administration 10 days, control group administered physiological saline 0.3ml will grow color Pu EAC tumor pearl under aseptic condition on the 8th day, with 1: 3 times (about 2,500 ten thousand cancerous cell) of normal saline dilution, at mice right fore subcutaneous abdomen inoculation 0.25ml, normally raised again 8 days, put to death mice on the 9th day, weigh respectively and get tumor and weigh, experimental group and matched group relatively have significant inhibitory effect, average tumour inhibiting rate 70%.
Medicine of the present invention is tested through allergy, and hemolytic test, abnormal toxicity test show that injection is nontoxic, have no side effect drug safety.The present invention is 56% to hepatocarcinoma and patients with lung cancer cure rate, is 65% to breast carcinoma and uterus carcinoma patient cure rate, to other cancer patient cure and effective percentage about 68%.In clinical hundreds of cancer patients, in being, terminal cancer shifts the patient, except that cure rate, coefficient of stabilization reaches that survival rate reaches more than 93% more than 80%, one year.
The specific embodiment
Embodiment 1: take by weighing raw material by following proportioning: Resina garciniae 5g, Pollen Pini 250g, Rhizoma Dioscoreae Bulbiferae 100g, Periostracum Serpentis 100g, Coniogramme japonica (Thunb.) Diels 150g, Fructus actinidiae chinensis 250g, Herba Portulacae Grandiflorae 90g, Herba Lobeliae Chinensis 50g, Herba Hedyotidis Diffusae 150g, Scorpio 10g, Radix Semiaquilegiae 50g, Herba Solani Nigri 90g, Arisaema Cum Bile 30g, Rhizoma Belamcandae 100g, Herba Galii Teneri 150g, Herba Sedi Linearis 170
G, Herba Plantaginis 250g, Herba Violae japonicae 250g, Bufo siccus 90g, Herba Sonerilae cantonensis 90g, Herba Solani Surattensis 90g, purplish or white patches on the skin eggplant 70g, Spica Prunellae 250g, Herba Acalyphae 250g, Flos Daturae 90g, Rhizoma Dioscoreae 150g, Radix Glycyrrhizae 350g.
Preparation method is: Pollen Pini is put into 100 ℃ of water and is stirred and make paste, places in 0.5 liter the hot water again, and 100 ℃ of water temperatures are soaked and got supernatant in 3 hours, and twice filtration repeatedly merges 2 times supernatant, and be standby.Resina garciniae, Rhizoma Dioscoreae Bulbiferae, levigation, getting supernatant in 8 hours with 80 ℃ of water loggings bubble of 0.5 liter, to fry in shallow oil into paste three times standby.Periostracum Serpentis Testa Tritici parching to brown is pulverized.Scorpio, Bufo siccus fire preparing salt are fried, chopping is used as medicine.Surplus medicine is concocted or is handled the back, pulverizes by the Pharmacopoeia of the People's Republic of China; Or each medicine is directly bought in Chinese medicine market, pulverizing gets final product.
The above-mentioned Chinese medicine for preparing and extract inserted add 4~5 premium on currency in the container, water temperature was boiled 40 minutes for 100 ℃, filtered, and took out clear liquid, and spice adds 3~4 premium on currency again and boils after 40 minutes and take out clear liquid, repeats once again.3 decocting liquids are merged, and freezing precipitation was got the Chinese herbal medicine extractum that supernatant concentration becomes water content 45-50% after 20 hours, by every 50g extractum adding distil water 1000ml, heat 100 ℃, fried in shallow oil plate-and-frame filtration 45 minutes, filtrate adding, account for the active carbon and 0 of volume ratio 0.05-0.08%, the tween 80 of 03-0.05% volume ratio, and transfer pH to 7 with 1.2% NaOH, add 1000 ml distilled waters after the filtration again, use the G filter stick, outsourcing filter paper and thick cloth C3 filter bulb 0.45 μ filtering with microporous membrane.Filtrate is through fill, sealing by fusing sterilization, and packing 2ml pacifies the bottle injection.
Medication every day once, 21 days is a course of treatment, a 2ml adopts the intramuscular injection injection.Treatment, short treating period, fast, the medication handy and safe of curative effect are convenient to treat, are made things convenient for to injection of the present invention, can be used for treating various cancers and tumor.
Embodiment 2: take by weighing raw material by following proportioning: Resina garciniae 6g, Pollen Pini 280g, Rhizoma Dioscoreae Bulbiferae 80g, Periostracum Serpentis 110g, Coniogramme japonica (Thunb.) Diels 170g, Fructus actinidiae chinensis 260g, Herba Portulacae Grandiflorae 80g, Herba Lobeliae Chinensis 55g, Herba Hedyotidis Diffusae 130g, Scorpio 18g, Radix Semiaquilegiae 40g, Herba Solani Nigri 100g, Arisaema Cum Bile 10g, Rhizoma Belamcandae 80g, Herba Galii Teneri 155g, Herba Sedi Linearis 140g, Herba Plantaginis 230g, Herba Violae japonicae 260g, Bufo siccus 95g, Herba Sonerilae cantonensis 80g, Herba Solani Surattensis 95g, purplish or white patches on the skin eggplant 80g, Spica Prunellae 240g, Herba Acalyphae 230g, Flos Daturae 110g, Rhizoma Dioscoreae 180g, Radix Glycyrrhizae 370g.
Preparation method is: Pollen Pini is put into 100 ℃ of water and is stirred and make paste, places in 0.5 liter the hot water again, and 100 ℃ of water temperatures are soaked and got supernatant in 3 hours, and twice filtration repeatedly merges 2 times supernatant, and be standby.Resina garciniae, Rhizoma Dioscoreae Bulbiferae, levigation, getting supernatant in 8 hours with 80 ℃ of water loggings bubble of 0.5 liter, to fry in shallow oil into paste three times standby.Periostracum Serpentis Testa Tritici parching to brown is pulverized.Scorpio, Bufo siccus fire preparing salt are fried, chopping is used as medicine.Get Rhizoma Dioscoreae and be ground into the powder that to cross 100 mesh sieves.Surplus medicine is concocted or is handled the back, pulverizes by the Pharmacopoeia of the People's Republic of China; Or each medicine is directly bought in Chinese medicine market, pulverizing gets final product.Periostracum Serpentis, Scorpio, Bufo siccus are added the conventional water yield together with the surplus medicine of pulverizing to be decocted 3-4 time, get decoction liquor and merge Pollen Pini, Resina garciniae, Rhizoma Dioscoreae Bulbiferae supernatant, concentrate, be prepared into extract powder by the pharmacopeia standard, add, cross the Rhizoma Dioscoreae powder of 100 mesh sieves, be mixed, oven dry, pulverize, add the starch that accounts for medicated powder total amount 5~15%, be mixed, incapsulate.
Capsule of the present invention, oral usually, the twice-daily of being grown up, one time two, adorn 5 grams for every, the child reduces by half, with warm boiled water (taking medicine before meal with).Can be used for treating various cancers and tumor.
Embodiment 3: take by weighing raw material by following proportioning: Resina garciniae 7g, Pollen Pini 230g, Rhizoma Dioscoreae Bulbiferae 90g, Periostracum Serpentis 80g, Coniogramme japonica (Thunb.) Diels 130g, Fructus actinidiae chinensis 240g, Herba Portulacae Grandiflorae 70g, Herba Lobeliae Chinensis 75g, Herba Hedyotidis Diffusae 160g, Scorpio 10g, Radix Semiaquilegiae 70g, Herba Solani Nigri 70g, Arisaema Cum Bile 50g, Rhizoma Belamcandae 100g, Herba Galii Teneri 175g, Herba Sedi Linearis 170g, Herba Plantaginis 270g, Herba Violae japonicae 240g, Bufo siccus 70g, Herba Sonerilae cantonensis 100g, Herba Solani Surattensis 70g, purplish or white patches on the skin eggplant 80g, Spica Prunellae 255g, Herba Acalyphae 255g, Flos Daturae 70g, Rhizoma Dioscoreae 130g, Radix Glycyrrhizae 320g.Method for making and usage are with embodiment 2.After also the above-mentioned raw materials medicine can being concocted or handled by the Pharmacopoeia of the People's Republic of China, pack adds constant water, connects and to fry in shallow oil 3 times, and collecting decoction is made decoct, the clothes decocting liquid, every day secondary, each 150 grams are so be not repeated.
In a word, the effect with anticancerization tumor, anti-inflammatory analgetic, reparation body injury of the present invention, and toxic and side effects is little, and cost hangs down good effect.

Claims (3)

1. medicine for the treatment of cancer, it is characterized in that: it is the medicine of being made by the following weight proportion raw material:
Figure FSA00000557093000011
2. a kind of medicine for the treatment of cancer according to claim 1, it is characterized in that: wherein the weight proportion of each raw material is:
Figure FSA00000557093000012
3. a kind of medicine for the treatment of cancer according to claim 1, it is characterized in that: wherein the weight proportion of each raw material is:
Figure FSA00000557093000013
Figure FSA00000557093000021
CN2011102336846A 2011-08-16 2011-08-16 Drug for treating cancer Expired - Fee Related CN102283976B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103494963A (en) * 2013-10-09 2014-01-08 颜文超 Special medicated diet for treating stomach cancer
CN104888146A (en) * 2015-06-30 2015-09-09 叶学忠 Anti-cancer Chinese herbal medicine
CN108434245A (en) * 2018-06-20 2018-08-24 广东工业大学 A kind of plant button son eggplant extract and its preparation method and application
CN112717032A (en) * 2021-01-13 2021-04-30 良赛电气(上海)有限公司 A Chinese medicinal composition for treating cancer and malignant tumors

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101700386A (en) * 2009-11-12 2010-05-05 范先明 Traditional Chinese medicine composition resistant to liver cancer and medicine coat thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101700386A (en) * 2009-11-12 2010-05-05 范先明 Traditional Chinese medicine composition resistant to liver cancer and medicine coat thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103494963A (en) * 2013-10-09 2014-01-08 颜文超 Special medicated diet for treating stomach cancer
CN104888146A (en) * 2015-06-30 2015-09-09 叶学忠 Anti-cancer Chinese herbal medicine
CN108434245A (en) * 2018-06-20 2018-08-24 广东工业大学 A kind of plant button son eggplant extract and its preparation method and application
CN112717032A (en) * 2021-01-13 2021-04-30 良赛电气(上海)有限公司 A Chinese medicinal composition for treating cancer and malignant tumors

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