CN112717032A - A Chinese medicinal composition for treating cancer and malignant tumors - Google Patents
A Chinese medicinal composition for treating cancer and malignant tumors Download PDFInfo
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- CN112717032A CN112717032A CN202110043534.2A CN202110043534A CN112717032A CN 112717032 A CN112717032 A CN 112717032A CN 202110043534 A CN202110043534 A CN 202110043534A CN 112717032 A CN112717032 A CN 112717032A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/86—Violaceae (Violet family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Abstract
The invention discloses a Chinese medicinal composition for rehabilitation of cancers and various malignant tumors, which comprises the following raw materials in part by weight: 6-9 parts of pseudo-ginseng, 0.02-0.04 part of macula extraction agent, 0.1-0.5 part of artificial musk, 3-9 parts of ginseng and 9-11 parts of coltsfoot root. The invention can protect the patient from being damaged by drugs and other substances, improve the physique of the patient, enhance the functions of an immune system and a self-healing system and prevent the cancer cells from being copied.
Description
Technical Field
The invention relates to the technical field of treatment of cancers and various malignant tumors, in particular to a Chinese medicinal composition for rehabilitation of cancers and various malignant tumors.
Background
At present, the lack of comprehensive deconstruction reports on the study and treatment of cancer drugs as a script for the disruption of cancer, which is the key to the frequent failure of cancer therapy, has hitherto involved four approaches in the global medical field to overcome the conventional treatment of cancer: 1. performing surgery; 2. chemotherapy; 3. radiotherapy; 4. targeted therapy; although the above treatment means are widely used, people not only continuously suffer great pain in the rehabilitation process as carriers of the disease, but also have unsatisfactory cure rate, which is the limitation of western medicine therapy.
The traditional Chinese medicine composition provided in the prior art has poor healing effect on cancer and malignant tumors, so that further improvement treatment is needed.
Disclosure of Invention
The invention aims to provide a Chinese medicinal composition for treating cancers and various malignant tumors, and aims to solve the problems in the background art.
In order to achieve the purpose, the invention provides the following technical scheme:
the invention provides a Chinese medicinal composition for treating cancers and various malignant tumors, which comprises the following raw materials in part by weight: 6-9 parts of pseudo-ginseng, 0.02-0.04 part of macula extraction agent, 0.1-0.5 part of artificial musk, 3-9 parts of ginseng and 9-11 parts of coltsfoot root.
Preferably, the feed comprises the following raw materials in parts by weight: 7-8 parts of pseudo-ginseng, 0.03-0.04 part of macleaya cordata extractant, 0.2-0.4 part of artificial musk, 4-8 parts of ginseng and 10-11 parts of coltsfoot root.
Preferably, 7.5 parts of pseudo-ginseng, 0.03 part of macleaya cordata extractant, 0.3 part of artificial musk, 6 parts of ginseng and 10 parts of plowshare.
Preferably, the preparation method of the speckle extracting agent comprises the following steps:
s1: cleaning the maculopathy chelate with clear water, adding deionized water with the weight 1-5 times of the weight of the maculopathy chelate, and then carrying out primary boiling treatment;
s2: performing ultrasonic treatment at 22-23kHz for 35-45min, boiling for the second time, filtering to obtain filtrate, and mixing filtrates;
s3: adding the filter residue into 1-3 times of 75-80% alcohol solution, performing ultrasonic treatment, centrifuging, mixing all centrifugates, and mixing with the filtrate in S2 to obtain the macula chelate extraction agent.
Preferably, the primary boiling treatment temperature is 90-110 ℃, and the boiling time is 10-20 min; the second boiling temperature is 95 deg.C, and boiling for 20-30 min.
Preferably, the power of the ultrasonic treatment in S3 is 28-30kHz, and the ultrasonic treatment is 50-60 min.
Preferably, the power of the ultrasonic treatment is 29kHz and the ultrasonic treatment is 55 min.
Pseudo-ginseng: notoginsenoside, volatile oil potassium and manganese: the functional indications are as follows: removing blood stasis, stopping bleeding, relieving swelling, relieving pain, promoting hemoptysis, hematemesis, hematochezia, traumatic hemorrhage, and traumatic injury;
and (4) spot chelating: cantharidin, volatile oil, formic acid, arsenic, barium and bismuth; the functional indications are as follows: blood stasis removing, blood stasis inducing and blood stasis removing, and red blood inducing and foaming, and can be used for treating abdominal mass;
artificial musk: polypeptide, arginine, potassium, calcium; the functional indications are as follows: promoting blood circulation, dredging channels, relieving swelling and pain;
ginseng: ginsenoside, notoginsenoside, volatile oil, linoleic acid, polypeptide, protein, and folic acid; the functional indications are as follows: invigorating primordial qi, promoting fluid production, and tranquilizing mind, and can be used for treating asthenia, cold limbs, slight pulse, thirst due to body fluid consumption, and heart failure;
ploughshare grass: brass, selenium, lead; the functional indications are as follows: clearing away heat and toxic material, relieving swelling and dissipating stagnation.
Compared with the prior art, the invention has the following beneficial effects:
after being taken by a cancer patient, the traditional Chinese medicine composition is digested into various amino acids through the spleen and the stomach, the amino acids are converted into ascorbic acid and protein which are absorbed and transported by the kidney to be normally repaired in each damaged organ, and the healthy organs are established to normally operate, so that the functions of improving NK cells, B cells, T cells, TNF cells and macrophages in an immune system are realized, and the functions of resisting the invasion of cells, germs and the like of the patient by leukocytes are also improved; the invention can protect the patient from being damaged by drugs and other substances, improve the physique of the patient, enhance the functions of an immune system and a self-healing system and prevent the cancer cells from being copied.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below with reference to specific embodiments, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1:
the Chinese medicinal composition for treating the cancers and various malignant tumors comprises the following raw materials in parts by weight: 6 parts of pseudo-ginseng, 0.02 part of a macula extraction agent, 0.1 part of artificial musk, 3 parts of ginseng and 9 parts of plowshare.
The preparation method of the cantharis extracting agent of the embodiment comprises the following steps:
s1: cleaning the maculopathy chelate with clear water, adding deionized water with the weight 1 time that of the maculopathy chelate, and then carrying out primary boiling treatment;
s2: then performing ultrasonic treatment at 22kHz for 35min, performing secondary boiling treatment, filtering to obtain filtrate, and mixing the filtrates;
s3: adding the filter residue into 1 time of 75% alcohol solution by volume fraction, then carrying out ultrasonic treatment, centrifuging, combining all centrifugate, and then combining with the filtrate in S2 to obtain the cantharides extractant.
In the embodiment, the primary boiling treatment temperature is 90 ℃, and the boiling time is 10 min; the secondary boiling temperature is 95 deg.C, and boiling for 20 min.
The power of the ultrasonic treatment in S3 of the present example was 28kHz, and the ultrasonic treatment was carried out for 50 min.
Example 2:
the Chinese medicinal composition for treating the cancers and various malignant tumors comprises the following raw materials in parts by weight: 9 parts of pseudo-ginseng, 0.04 part of a macula extraction agent, 0.5 part of artificial musk, 9 parts of ginseng and 11 parts of plowshare.
The preparation method of the cantharis extracting agent of the embodiment comprises the following steps:
s1: cleaning the maculopathy chelate with clear water, adding deionized water with the weight 1-5 times of the weight of the maculopathy chelate, and then carrying out primary boiling treatment;
s2: then performing ultrasonic treatment at 23kHz for 45min, performing secondary boiling treatment, filtering to obtain filtrate, and mixing the filtrates;
s3: adding the filter residue into 3 times of 80% alcohol solution by volume, then performing ultrasonic treatment, centrifuging, combining all centrifugates, and then combining with the filtrate in S2 to obtain the cantharides extractant.
In the embodiment, the primary boiling treatment temperature is 110 ℃, and the boiling time is 20 min; the second boiling temperature is 95 deg.C, and boiling for 30 min.
The power of the ultrasonic treatment in S3 of this example was 30kHz and 60min of ultrasonic treatment.
Example 3:
the Chinese medicinal composition for treating the cancers and various malignant tumors comprises the following raw materials in parts by weight: 7.5 parts of pseudo-ginseng, 0.03 part of a macula extraction agent, 0.3 part of artificial musk, 6 parts of ginseng and 10 parts of viola prostrata.
The preparation method of the cantharis extracting agent of the embodiment comprises the following steps:
s1: cleaning the mackerel by using clean water, adding deionized water with the weight being 3 times of that of the mackerel, and then carrying out primary boiling treatment;
s2: then carrying out ultrasonic treatment at 22.5kHz for 40min, then carrying out secondary boiling treatment, then filtering to obtain filtrate, and combining the filtrate;
s3: adding the filter residue into 2 times of 77.5% alcohol solution by volume, then performing ultrasonic treatment, centrifuging, combining all centrifugates, and then combining with the filtrate in S2 to obtain the cantharides extractant.
In the embodiment, the primary boiling treatment temperature is 100 ℃, and the boiling time is 15 min; the secondary boiling temperature is 95 deg.C, and boiling for 25 min.
The power of the ultrasonic treatment in S3 of the present example was 29kHz and 55min of ultrasonic treatment.
The using method comprises the following steps:
pulverizing Notoginseng radix, artificial Moschus, Ginseng radix, and herba Violae japonicae into 500-mesh powder of 800 meshes, adding the speckle and chelate extractant, blending and stirring, and applying once every 20 h;
experimental example 1:
the human cervical carcinoma Hela cell strain is selected and cultured by DMEM culture solution containing 10% fetal calf serum under the conditions of 3 ℃, 5% CO2 concentration and saturation humidity. When the cells grow to the logarithmic phase, the cells are digested by 25% pancreatin, washed and blown off, and diluted to 106/mL, and 100 mu L of the cells are inoculated in a 96-well plate for preparing MTT experiments;
when the medicament of the embodiments 1-3 of the invention is used for measuring the inhibition rate of the cells, the inhibition rate can respectively reach 15.2%, 15.8% and 16.1%, and the medicament of the invention can effectively play the role of anti-tumor.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (7)
1. A Chinese medicinal composition for treating cancers and various malignant tumors is characterized by comprising the following raw materials in parts by weight: 6-9 parts of pseudo-ginseng, 0.02-0.04 part of macula extraction agent, 0.1-0.5 part of artificial musk, 3-9 parts of ginseng and 9-11 parts of coltsfoot root.
2. A Chinese medicinal composition for treating cancers and various malignant tumors is characterized by comprising the following raw materials in parts by weight: 7-8 parts of pseudo-ginseng, 0.03-0.04 part of macleaya cordata extractant, 0.2-0.4 part of artificial musk, 4-8 parts of ginseng and 10-11 parts of coltsfoot root.
3. The Chinese medicinal composition for rehabilitation of cancer and various malignant tumors according to claim 1, wherein the panax notoginseng 7.5 parts, the banca extractant 0.03 part, the artificial musk 0.3 part, the ginseng 6 parts, and the viola japonica 10 parts.
4. The Chinese medicinal composition for rehabilitation of cancer and various malignant tumors according to claim 1, wherein the preparation method of the cantharis extracting agent comprises:
s1: cleaning the maculopathy chelate with clear water, adding deionized water with the weight 1-5 times of the weight of the maculopathy chelate, and then carrying out primary boiling treatment;
s2: performing ultrasonic treatment at 22-23kHz for 35-45min, boiling for the second time, filtering to obtain filtrate, and mixing filtrates;
s3: adding the filter residue into 1-3 times of 75-80% alcohol solution, performing ultrasonic treatment, centrifuging, mixing all centrifugates, and mixing with the filtrate in S2 to obtain the macula chelate extraction agent.
5. The Chinese medicinal composition for rehabilitation of cancer and various malignant tumors according to claim 4, wherein the one-time boiling treatment temperature is 90-110 ℃, and the boiling time is 10-20 min; the second boiling temperature is 95 deg.C, and boiling for 20-30 min.
6. The Chinese medicinal composition for rehabilitation of cancer and various malignant tumors according to claim 4, wherein the power of the ultrasonic treatment in S3 is 28-30kHz and the ultrasonic treatment is 50-60 min.
7. The Chinese medicinal composition for rehabilitation of cancer and various malignant tumors according to claim 6, wherein the power of ultrasonic treatment is 29kHz and 55min of ultrasound.
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Citations (3)
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CN102283976A (en) * | 2011-08-16 | 2011-12-21 | 曹春徕 | Drug for treating cancer |
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CN110917229A (en) * | 2019-12-25 | 2020-03-27 | 仇永华 | Formula for treating early and medium stage lymphoma |
-
2021
- 2021-01-13 CN CN202110043534.2A patent/CN112717032A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102283976A (en) * | 2011-08-16 | 2011-12-21 | 曹春徕 | Drug for treating cancer |
CN103861079A (en) * | 2014-03-14 | 2014-06-18 | 杨峻峻 | Traditional Chinese medicine composition with effects of clearing heat, relieving pain and eliminating tumors |
CN110917229A (en) * | 2019-12-25 | 2020-03-27 | 仇永华 | Formula for treating early and medium stage lymphoma |
Non-Patent Citations (3)
Title |
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次旦旺久等: "斑蝥提取物诱导宫颈癌细胞凋亡机制的实验研究", 《中国中西医结合杂志》 * |
陈旭伟等: "人参皂苷Compound K对宫颈癌细胞增殖和凋亡的影响", 《中国临床药理学杂志》 * |
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