CN102245604A - 抗病毒化合物 - Google Patents

抗病毒化合物 Download PDF

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Publication number
CN102245604A
CN102245604A CN2009801499565A CN200980149956A CN102245604A CN 102245604 A CN102245604 A CN 102245604A CN 2009801499565 A CN2009801499565 A CN 2009801499565A CN 200980149956 A CN200980149956 A CN 200980149956A CN 102245604 A CN102245604 A CN 102245604A
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CN
China
Prior art keywords
independently
carbocyclyl
occurrence
hydrogen
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2009801499565A
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English (en)
Chinese (zh)
Inventor
D.A.德盖
P.L.多纳
W.M.凯蒂
C.W.赫钦斯
A.C.克吕格
J.T.兰多夫
C.E.莫特
P.克里什南
N.C.米斯特里
T.J.皮罗特-马蒂亚斯
S.V.帕特尔
X.李
T.N.索尔特维德尔
L.T.奈尔逊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AbbVie Inc
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of CN102245604A publication Critical patent/CN102245604A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN2009801499565A 2008-12-23 2009-12-22 抗病毒化合物 Pending CN102245604A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14031808P 2008-12-23 2008-12-23
US61/140318 2008-12-23
PCT/US2009/069188 WO2010075380A1 (en) 2008-12-23 2009-12-22 Anti-viral compounds

Publications (1)

Publication Number Publication Date
CN102245604A true CN102245604A (zh) 2011-11-16

Family

ID=42167446

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801499565A Pending CN102245604A (zh) 2008-12-23 2009-12-22 抗病毒化合物

Country Status (10)

Country Link
US (2) US8546405B2 (enExample)
EP (1) EP2367823A1 (enExample)
JP (1) JP2012513410A (enExample)
CN (1) CN102245604A (enExample)
CA (1) CA2740195A1 (enExample)
MX (1) MX2011006333A (enExample)
RU (1) RU2505539C2 (enExample)
SG (1) SG172353A1 (enExample)
WO (1) WO2010075380A1 (enExample)
ZA (1) ZA201105356B (enExample)

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