CN102227974A - Method for conserving radix angelicae through storage - Google Patents

Method for conserving radix angelicae through storage Download PDF

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CN102227974A
CN102227974A CN2011101470265A CN201110147026A CN102227974A CN 102227974 A CN102227974 A CN 102227974A CN 2011101470265 A CN2011101470265 A CN 2011101470265A CN 201110147026 A CN201110147026 A CN 201110147026A CN 102227974 A CN102227974 A CN 102227974A
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storage
root
dahurain angelica
antagonist
putting
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蒋桂华
马逾英
卢先明
兰志琼
杨曦
杨莎
陈佳妮
赵芙蓉
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Chengdu University of Traditional Chinese Medicine
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Chengdu University of Traditional Chinese Medicine
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Abstract

The invention provides a method for conserving radix angelicae through storage. The method is characterized in that an antagonistic storage method is adopted for conservation; and the antagonistic storage method is characterized by taking seaweed, galangal or tree peony bark as an antagonist and conserving the antagonist and radix angelicae with a weight ratio of 1: (2.5-10) by mixed putting, layer-by-layer isolated putting or buried putting. Radix angelicae has a certain inhibitory effect on xylene-induced mouse ear edema after being conserved for 3 years by adopting the antagonistic storage method, thus showing that radix angelicae still has pesticide effect after being conserved for 3 years.

Description

A kind of storage maintenance process of the root of Dahurain angelica
Technical field
The present invention relates to a kind of storage maintenance process of the root of Dahurain angelica.
Background technology
The root of Dahurain angelica is large medicinal herbs most in use kind, in traditional Chinese medicine, occupy critical role, because root of Dahurain angelica fragrance is strong, is rich in starch, it is mouldy, spoiled easily to damage by worms in the storage, make moist, therefore, maintenance is preserved after adopting sulfur fumigation in the place of production more, is insect-pest, can place airtight the fumigating about 5 days of phosphatization aluminium flake every year in the storehouse twice, at present in its main producing region---the Suining, Sichuan, adopt the sulphuring drying exactly.And a large amount of bibliographical informations this kind method make that root of Dahurain angelica active constituent content descends, drug action reduces, had a strong impact on angelica root quality (exceed English etc. as horse, sulphuring angelica anomala medicinal material is to the influence of mouse analgesic activity, West China pharmaceutical journal, 2006 years 6 phases).Therefore, need the novel habitat processing method of seeking a kind of alternative sulphuring badly,, and reduce environmental pollution with the safety and the validity of assurance medicinal material.
Antagonism is one of traditional Chinese medicine method of curing with storage method (antagonism preservative), and this method is simple and easy to do, does not pollute medicinal material and environment, to the traditional Chinese medicine and the people, animal safety non-toxic of storage.Common Chinese medicine antagonism has with the storage method: rhizoma alismatis, Chinese yam and the root bark of tree peony can insect protected be protected look with storage; Safflower and Cordyceps sinensis can make Cordyceps sinensis storage for a long time not bad with the environment of storing in low temperature drying; The coexistence of the same Gorgon fruit of garlic, coix seed can prevent that Gorgon fruit, coix seed are infested; The root of Chinese wild ginger, Chinese prickly ash protects pilose antler; Cubeb is driven away aflatoxins; The anti-Moschus of Radix Angelicae Sinensis is walked complexion etc.
Antagonism is broadly divided into 4 kinds with the laying method of storage method: one, intersect with putting, the parcel post of two kinds of medicinal materials is crossed one another to stack, and be usually used in the big medicinal material of storage capacity, but effect is relatively poor; Two, layering is isolated with putting, and two kinds of medicinal materials intersect layer by layer to bury and put in case or tube, separates with gunnysack or other ventilative things between two-layer, and is effective; Three, mixing is put together, two kinds of medicinal materials is mixed together put, or do not add isolation in the placement of intersection mixing layer by layer, and is effective; Four, bury and put, hold a kind of medicinal material, bury in the another kind of traditional Chinese medicine that is put in the bulk container with little gunnysack or woven bag, effective.
At present, the existing report that adopts antagonism to come the maintenance angelica root with the storage method.Wang Shumei intersects the root of Dahurain angelica with putting with galangal, and the rate of damaging by worms of the root of Dahurain angelica is put than singly little (Wang Shumei, traditional Chinese medicine protects the pre-test of prescription method with medicine in storing, traditional Chinese medicine, 1998 21 6 phases of volume); It is antagonist that Zhang Changquan selects sea-tangle for use, gets the 0.2Kg sea-tangle and mixes with the 0.5Kg root of Dahurain angelica with putting the phenomenon that effectively prevented to damage by worms (Zhang Changquan etc., the experimental phenomena of sea-tangle antagonism storage Chinese medicine, basic unit's Chinese medicine magazine, 1994 82 phases of volume).
Though antagonism is widely used with the storage method, how to select holding conditions, the maintenance angelica root makes that its storage time is longer better, remains the focus of current research.
Summary of the invention
Technical scheme of the present invention has provided a kind of storage maintenance process that prevents that effectively the root of Dahurain angelica is mouldy, damages by worms.
The invention provides a kind of storage maintenance process of the root of Dahurain angelica, it is to adopt antagonism to preserve maintenance with the storage method; Wherein, antagonism is to be antagonist with sea-tangle, galangal or moutan bark with the storage method, with antagonist with the root of Dahurain angelica by mix with put, layering isolates with putting or bury the mode of putting and preserves, the weight proportion of the antagonist and the root of Dahurain angelica is 1: 2.5-10.
Further, antagonist being isolated the mode of putting together with the root of Dahurain angelica by layering preserves.
Wherein, layering is isolated the method for putting together and is: the root of Dahurain angelica and antagonist are alternately placed, and one deck root of Dahurain angelica, one deck antagonist, interlayer separates with breathable fabric.
Wherein, described breathable fabric is linen or bafta; Bafta has advantages such as moisture absorption, good permeability, but aging fast, easily mildews; Linen is similar to bafta, but gas permeability is better, and the antifungi performance is good, is difficult for mouldyly, and mothproof effect is good.
Further preferably, described breathable fabric is a linen, for example megila, sodolin etc., and common have gunnysack, burlap, a gauze etc.
Further, the weight proportion of the antagonist and the root of Dahurain angelica is 1: 2.5-5.
A nearlyer step ground, the weight proportion of the antagonist and the root of Dahurain angelica is 1: 2.5 or 1: 5.
Further, described antagonist is a sea-tangle.
Wherein, when adopting antagonism, also adopt with the storage method 60C0-gamma-ray irradiation sterilization.
Further, in the process that adopts antagonism with the storage method, when the root of Dahurain angelica is damaged by worms phenomenon, adopt 60C0-gamma-ray irradiation sterilization.
A nearlyer step ground, described 60The radiation parameter of C0-gamma-ray irradiation sterilization is cobalt-60 irradiation 30 minutes, amount of radiation 8Kgy.
The storage practice of the root of Dahurain angelica of the present invention be with the sea-tangle be antagonist, layering isolate with put, antagonist be 1: 2.5 or 1: 5 by maintenance medicinal material ratio, in storage,, also need adopt cobalt-60 radiation sterilization as if damaging by worms phenomenon.The root of Dahurain angelica is being preserved maintenance after 3 years through the antagonism preservative, and paraxylene causes mice auricle swelling certain inhibitory action, this shows, the root of Dahurain angelica of preserving after 3 years still has drug effect.
Though bibliographical information mix with put, layering isolates that to put these three kinds of methods be that the Chinese medicine antagonism is with the laying method commonly used in the storage method with putting, burying, and three's storage effect is all very good, but, the present invention finds in the storage test process to the root of Dahurain angelica, in the numerous factors of antagonism with storage, storage method has the influence (P<0.05) of highly significant to the root of Dahurain angelica quality of long term storage, therefore, preferred layering is isolated with putting this modes of emplacement, to reach best antagonism storage effect among the present invention.
Obviously, according to foregoing of the present invention,,, can also make modification, replacement or the change of other various ways not breaking away under the above-mentioned basic fundamental thought of the present invention prerequisite according to the ordinary skill knowledge and the customary means of this area.
The embodiment of form is described in further detail foregoing of the present invention again by the following examples.But this should be interpreted as that the scope of the above-mentioned theme of the present invention only limits to following example.
All technology that realizes based on foregoing of the present invention all belong to scope of the present invention.
Embodiment
Embodiment 1 root of Dahurain angelica storage maintenance process of the present invention
Get root of Dahurain angelica 3Kg, sea-tangle 0.6Kg adopts layering to isolate with putting method (two interlayers separate with gauze), and sea-tangle is preserved in gunnysack with the root of Dahurain angelica.
Embodiment 2 root of Dahurain angelica storage maintenance processes of the present invention
Get root of Dahurain angelica 3Kg, sea-tangle 1.2Kg adopts layering to isolate with putting method (two interlayers separate with burlap), and sea-tangle is preserved in carton with the root of Dahurain angelica.
Embodiment 3 root of Dahurain angelica storage maintenance processes of the present invention
Get root of Dahurain angelica 3Kg, sea-tangle 1.2Kg adopts layering to isolate with putting method (two interlayers separate with the piece of sack), and sea-tangle is preserved in wooden case with the root of Dahurain angelica; Simultaneously, also adopt 60C0-gamma-ray irradiation sterilization, 60The radiation parameter of C0-gamma-ray irradiation sterilization is: cobalt-60 irradiation 30 minutes, amount of radiation 8Kgy.
The screening of embodiment 4 root of Dahurain angelica storage maintenance processes of the present invention
1. experiment material
Medicinal material: the root of Dahurain angelica: purchase in root of Dahurain angelica GAP base, Suining, Sichuan on March 24th, 2007, penetrating judgment is awarded the dry root that is accredited as samphire Radix angelicae dahuricae Angelica dahurica (Fisch.exHoffm.) Benth.Et Hook.f.var.formosana (Boiss) Sham et Yuan. through Lu of Chengdu University of Traditional Chinese Medicine elder generation.
Galangal: purchase in Chengdu lotus pond Chinese Medicinal Materials Markets on March 23rd, 2007, penetrating judgment is awarded the dry rhizome that is accredited as zingiberaceous plant galangal Alpinia officinarum Hance. through Lu of Chengdu University of Traditional Chinese Medicine elder generation.
Moutan bark: purchase in Chengdu lotus pond Chinese Medicinal Materials Markets on March 23rd, 2007, penetrating judgment is awarded the dry root skin that is accredited as ranunculaceae peony Paeonia suffruticosa Andr. through Lu of Chengdu University of Traditional Chinese Medicine elder generation.
Sea-tangle: purchase in Chengdu lotus pond Chinese Medicinal Materials Markets on March 23rd, 2007, penetrating judgment is awarded the thallus that is accredited as Laminariaceae plant sea-tangle Laminaria japonica Arsch. through Lu of Chengdu University of Traditional Chinese Medicine elder generation.
Reagent, reagent: dimethylbenzene (analyzing pure), methyl alcohol (analyzing pure), 95% ethanol (analyzing pure), methyl alcohol (chromatographically pure), Imperatorin reference substance (Chinese biological goods institute for drug control).
Instrument: microphyte sample cracker FZ102 type (in Beijing emerging great achievement Instr Ltd.), the temperature adjustable electrically heated cover of ZDHW type (emerging Instr Ltd. in the Huanghua City, Hebei province), BS200S electronic balance (Beijing Sai Duolisi balance Co., Ltd), DZKW-4 type electronic thermostatic water-bath (in Beijing emerging great achievement Instr Ltd.), KQ-50B type ultrasonic cleaning machine (Kunshan Ultrasonic Instruments Co., Ltd.), the horizontal Cryo Equipment refrigerator of the DB255-LT/100LT of Haier (Qingdao HaiEr Co., Ltd), far infrared radiation drying box 766-type (Shanghai sunlight experimental instrument Co., Ltd), Glanz WD900 type micro-wave oven (Glanshi Electric Appliance Industry Co Ltd, Shunde City), Tianjin, island UV1100 visible ultraviolet spectrophotometer (Shanghai Techcomp Instrument Ltd.), the Aglient1100 high performance liquid chromatograph, core filter SH/T0093 type (Great Wall, Jianhu County instrument Manufacturing Co., Ltd) etc.
2. experimental technique
2.1 root of Dahurain angelica storage maintenance process
The 1-9 group: antagonism maintenance group: under the natural conditions, lucifuge is stored, and packaging material are gunnysack.Concrete storage procedures is by following orthogonal array grouping maintenance.
This experimental group is chosen three principal elements: antagonist, laying method, antagonist and by the ratio of maintenance medicinal material.Each factor is intended 3 levels, has selected orthogonal table for use.See Table 1, table 2.
Table 1 factor level table L9 (34)
Figure BSA00000509566100041
Annotate: laying method is as follows:
Mix together and put: two kinds of medicinal materials are mixed together put, or intersection does not add isolation in the middle of mixing placement layer by layer.This experiment is adopted by the maintenance medicinal material and is mixed with antagonist with putting.
Layering is isolated with putting: in storage container, medicinal material and antagonist are alternately placed, one deck root of Dahurain angelica, one deck antagonist, interlayer separate this experiment with breathable fabric and adopt antagonist to be loaded in the sack made from gauze, will be divided into two-layer by the maintenance medicinal material.
Bury and put: hold a kind of medicinal material with little gunnysack or woven bag, bury in the another kind of medicinal material that is put in the bulk container.This experiment is adopted antagonist is loaded in the sack made from gauze, buries to be put in by in the maintenance medicinal material.
The 10th group: intermittently freezing group, will tighten sealing by the maintenance medicinal material with the medicinal plastic bag packaging of thick matter.Be put in the horizontal Cryo Equipment refrigerator of the DB255-LT/100LT of Haier, temperature is made as-20 ℃, takes out after freezing 7 days, and refrigerator is put in the also normal temperature preservation 7 days that heats up naturally again, and-20 ℃, freezing 7 days, take out, heat up naturally and the normal temperature preservation.
The 11st group: cobalt-60 irradiation sterilization group, be sent to Sichuan Province agricultural cience and farming techniques institute through cobalt-60 irradiation 30 minutes, amount of radiation 8Kgy by the maintenance medicinal material.
The 12nd group: far infrared radiation sterilization group, to be shone through far infrared radiation by the maintenance medicinal material, temperature is controlled at about 50 ℃, shines 24 hours.
The 13rd group: the microwave sterilization group, greater than 25 grams, firepower is set as low fire, toasts each 1 minute 2 times by maintenance medicinal material weight; Less than 25 grams, firepower is set as low fire, toasts each 30 seconds 2 times by maintenance medicinal material weight.
The 14th group: the aluminum phosphate group, be stored in jointly in the closed container by maintenance medicinal material and commercially available aluminum phosphate (containing auxiliary material), the aluminum phosphate bulk storage is around medicine, and consumption is 5-6 gram/m 3, about 10.
Control group:
The 15th group: blank group, do not put together by the maintenance medicinal material with any antagonist, keep in Dark Place.
The 16th group: the sulphuring group, after handling by place of production tradition sulphuring method, keep in Dark Place.
2.2 root of Dahurain angelica storage maintenance observation
The storage totally 3 years phase of maintenance observation, promptly in March, 2007~2010 year March.All observation indexs are measured once before maintenance experiment beginning, in order to initial data.After this carry out every half a year once by the observation of maintenance root of Dahurain angelica appearance character and carry out the assay of moisture, alcohol extract, Imperatorin in conjunction with 2005 editions pharmacopeia.
3. experimental result
3.1 root of Dahurain angelica presentation quality situation of change in the storage
Root of Dahurain angelica appearance luster, smell do not have significant change in the storage, do not have the phenomenon of going rancid yet and occur.Meet that high-temperature high humidity season is easily damaged by worms, the moisture absorption, thereby cause and go mouldy, because of the maintenance process difference is damaged by worms, the moisture absorption, the situation of going mouldy difference to some extent.It wherein is antagonist with the galangal, layering is isolated with putting, burying and put two groups, is antagonist with the moutan bark, and mixing is put together, layering is isolated with putting two groups of situations of damaging by worms lighter, microwave radiation group and low temperature intermittently freezing group also be difficult for damaging by worms, but low temperature intermittently freezing group easily go mouldy.
Root of Dahurain angelica presentation quality observation watch in table 3 storage
Color and luster Smell Go rancid The moisture absorption Go mouldy Damage by worms
Before the maintenance Taupe Fragrance Do not have Do not have Do not have Do not have
After the maintenance 3 years Taupe Fragrance Do not have Do not have Do not have Part has channel
3.2 root of Dahurain angelica moisture and chemical index composition situation of change in the storage
Root of Dahurain angelica moisture table (%) (n=3) in table 4 storage
Figure BSA00000509566100061
As seen from the above table, moisture is no more than limiting the quantity of of pharmacopeia regulation substantially in the root of Dahurain angelica storage.
Root of Dahurain angelica alcohol extract contains scale (%) (n=3) in table 5 storage
Figure BSA00000509566100062
As shown in Table 5, whole storage period alcohol extract content be the level fluctuation substantially and change, do not have obviously and reduce.
Root of Dahurain angelica Imperatorin content (%) (n=3) in table 6 storage
By table 6 as seen, the storage of Imperatorin content obviously reduced after 12 months, and whole content is the fluctuation downward trend.
Table 5,6 data are integrated, are obtained table 7:
Table 7
As shown in table 7, the 1-14 group all is better than blank group (15), shows that the storage practice of 1-14 group all can be brought into play preservation effect preferably to the root of Dahurain angelica; Compare with sulphuring group (16), the Imperatorin content of 1-14 group all is higher than 16 groups, shows that other maintenance processes also can reach the preservation effect of sulphuring.
3.3 the screening of storage maintenance process
Adopt the aggregative weighted point system, give extract, the subjective weight coefficient 0.6,0.4 of Imperatorin respectively, (1-9 group) result carries out statistical analysis to root of Dahurain angelica antagonism maintenance experiment, the best antagonism of screening maintenance scheme.Root of Dahurain angelica antagonism sees Table 8 with storage maintenance aggregative weighted appraisal result, and adopts the SPSS15.0 software analysis, carries out variance analysis with the OD value, the results are shown in Table 9.
Table 8 optimization of orthogonal test root of Dahurain angelica antagonism storage maintenance measurement result (n=3)
Figure BSA00000509566100081
Table 9 The results of analysis of variance
Sum of squares Degree of freedom All square The F value p
A 41.7801 2 20.8900 18.66178 >0.05
B 82.8021 2 41.4011 36.98508 <0.05*
C 32.7054 2 16.3527 14.60845 >0.05
The 4th row 2.2388 2 1.1194
Summation 159.5264
Annotate: * P<0.05.
By variance analysis table as can be known: B factor (antagonist modes of emplacement) has and shows poor, is principal element, and A (antagonist), C (antagonist and by maintenance medicinal material ratio) they are secondary cause, wherein, and B>A>C.Because of this test index is that mark is the bigger the better, so the B factor is got 2 levels (layering is isolated with putting), the A factor is got 3 levels (sea-tangle), and the C factor is got 2 levels (1: 5), and promptly optimised process is A 3B 2C 2Because the C factor does not have statistical significance, also can get time good level--1 level (1: 2.5), antagonism is A with the storage testing program 3B 2C 1, promptly be with the sea-tangle antagonist, layering isolate with put, antagonist and be 1: 2.5 by maintenance medicinal material ratio.
The presentation quality evaluation is thought, the 8th group of root of Dahurain angelica presentation quality observed result in storage shows, the root of Dahurain angelica phenomenon that L can not occur going rancid in 3 years storages, because of it is rich in the easy moisture absorption of starch and is damaged by worms, the outer surface color does not have significant change, and the section color is deepened to some extent with the prolongation of storage time.This just shows that the 8th group of methods can effectively suppress the forfeiture of root of Dahurain angelica active ingredient, and mothproof moisture-proof role is obvious, but through after the storage for a long time in 3 years, the phenomenon of still damaging by worms.By table 7 as can be seen, in the maintenance process of 10-14 group, with 11 group of methods the bests, its active constituent content is higher than other several groups, therefore, in actual production, antagonism can be combined utilization with storage method and-60 irradiation sterilization methods, be in the storage with sea-tangle be antagonist, layering isolate with put, antagonist and be 1: 2.5 or 1: 5 by maintenance medicinal material ratio, in order to moisture absorption mildew-resistant antagonism storage together, then adopt cobalt-60 irradiation sterilization again when insect pest takes place, the condition of irradiation sterilization is: through cobalt-60 irradiation 30 minutes, and amount of radiation 8Kgy.
Moisture and assay: because the laboratory storehouse possesses dehumidification equipment, moisture is no more than limiting the quantity of of pharmacopeia regulation substantially in the root of Dahurain angelica storage, but high-temperature high humidity season moisture absorption moisture raises, and is respectively 0.5 year, 1.5 years, the 2.5 years moistures of surveying; Alcohol extract content storage promptly reduces after half a year to some extent, and after this content does not have the trend of obvious minimizing, whole storage period alcohol extract content be the level fluctuation substantially and change; Imperatorin content storage obviously reduced after 1 year, storage period Imperatorin content be the fluctuation downward trend.
Below further prove beneficial effect of the present invention by pharmacodynamics test.
Test example 1 root of Dahurain angelica storage of the present invention back pharmacodynamics evaluation study
Experimental result according to above-mentioned root of Dahurain angelica storage maintenance, choose the higher antagonism of comprehensive grading score with the storage group: the 8th group of (antagonist: sea-tangle, modes of emplacement: layering is isolated with putting, antagonist with by maintenance medicinal material ratio: 1: 5), the 11st group (cobalt-60 irradiation sterilization group), and the 15th group (blank maintenance group), the 16th group (sulphuring group) are carried out root of Dahurain angelica storage back pharmacodynamics evaluation study.Adopt the acetic acid twisting method to observe its analgesic activity, its antiinflammatory action is observed in the experiment of mice caused by dimethylbenzene xylene ear swelling.
1 experiment material
Animal: one-level Kunming mouse (Sichuan Academy of Medical Sciences experimental animal center, SCXK river 200415) body weight 18~22g.
Medicine: dexamethasone (081218), the new root of Dahurain angelica, the storage maintenance root of Dahurain angelica of producing in 2009 the celestial jade pendant in Zhejiang is made limited company, lot number:: the 8th group, the 11st group, the 15th group, the 16th group, and acetic acid, dimethylbenzene.
Main equipment: the card punch of balance, syringe, operating scissors, diameter 9mm etc.
2, the preparation method of sample
Getting above each root of Dahurain angelica sample powder 80g adds after an amount of 70% ethanol soaks into 4h, medicinal powder is packed in the percolation vat, use 70% ethanol percolation, collect percolate 480ml (flow velocity is 0.5ml/min), the concentrating under reduced pressure percolate makes the root of Dahurain angelica alcohol extract that concentration is 1g/ml to 80ml.
3, method and result
3.1 mice caused by dimethylbenzene xylene ear swelling experiment
Get 70 of male mices, male and female half and half are divided into physiological saline group (blank group), Dexamethasone group (20g/kg) at random, newly produce the root of Dahurain angelica, each group of the storage maintenance root of Dahurain angelica: the 8th group, the 11st group, the 15th group, the 16th group, and totally 7 groups, 10 every group.According to the form below dosage intraperitoneal injection, behind the administration 30min, evenly coat the positive and negative of each mouse auris dextra with dimethylbenzene 0.1ml, behind 30min, put to death, prick bottom left auris dextra sheet with the 9mm card punch at the same position of two ears, precision is weighed, and deducts the weight of left ear as auricle inflammatory swelling degree with the weight of auris dextra.Calculate right auricle swelling degree and press down swollen rate.
Each preserves the maintenance group and the physiological saline group more all demonstrates the effect of tangible antagonism mice caused by dimethylbenzene xylene auricle edema, but antiphlogistic effects the results are shown in Table 10 not as dexamethasone.
Table 10 storage back root of Dahurain angelica paraxylene causes the influence of mice auricle swelling
Figure BSA00000509566100101
Figure BSA00000509566100102
Compare * P<0.05, * * P<0.01 with the physiological saline group; Compare △ △ P<0.01 with Dexamethasone group
Above-mentioned effect experiment shows, the angelica root of the inventive method storage maintenance after 3 years still can be brought into play good antiinflammatory action, compare with the sulphuring group, the drug effect of the root of Dahurain angelica of the inventive method maintenance has the trend of increasing, comprehensive drug and content of effective, it is more effective than sulphuring to show that the present invention preserves maintenance process.
In sum, the storage practice of the root of Dahurain angelica of the present invention be with the sea-tangle be antagonist, layering isolate with put, antagonist and be 1: 2.5 or 1: 5 by maintenance medicinal material ratio; Can also when antagonism is with storage, carry out cobalt-60 radicidation.After 3 years, paraxylene causes mice auricle swelling certain inhibitory action to the root of Dahurain angelica through the storage maintenance.This shows that the root of Dahurain angelica of preserving after 3 years still has drug effect.Though bibliographical information mix with put, layering isolates that to put these three kinds of methods be that the Chinese medicine antagonism is with the laying method commonly used in the storage method with putting, burying, and three's storage effect is all very good, but, the present invention finds in the storage test process to the root of Dahurain angelica, in the numerous factors of antagonism with storage, storage method has the influence (P<0.05) (seeing Table 9) of highly significant to the root of Dahurain angelica quality of long term storage, therefore, preferred layering is isolated with putting this modes of emplacement, to reach best antagonism storage effect among the present invention.

Claims (10)

1. the storage maintenance process of a root of Dahurain angelica is characterized in that: it is to adopt antagonism to preserve maintenance with the storage method; Wherein, antagonism is to be antagonist with sea-tangle, galangal or moutan bark with the storage method, with antagonist with the root of Dahurain angelica by mix with put, layering isolates with putting or bury the mode of putting and preserves, the weight proportion of the antagonist and the root of Dahurain angelica is 1: 2.5-10.
2. storage maintenance process according to claim 1 is characterized in that: antagonist is isolated with the mode of putting by layering with the root of Dahurain angelica preserve.
3. storage maintenance process according to claim 1 and 2 is characterized in that: layering is isolated the method for putting together and is: the root of Dahurain angelica and antagonist are alternately placed, and one deck root of Dahurain angelica, one deck antagonist, interlayer separates with breathable fabric.
4. storage maintenance process according to claim 3 is characterized in that: described breathable fabric is linen or bafta.
5. storage maintenance process according to claim 4 is characterized in that: described breathable fabric is a linen.
6. according to any described storage maintenance process of claim 1-5, it is characterized in that: the weight proportion of the antagonist and the root of Dahurain angelica is 1: 2.5-5.
7. storage maintenance process according to claim 6 is characterized in that: the weight proportion of the antagonist and the root of Dahurain angelica is 1: 2.5 or 1: 5.
8. according to described storage maintenance process of claim 1-7 meaning, it is characterized in that: described antagonist is a sea-tangle.
9. storage maintenance process according to claim 1 is characterized in that: when adopting antagonism with the storage method, also adopt 60C0-gamma-ray irradiation sterilization.
10. storage maintenance process according to claim 9 is characterized in that: described 60The radiation parameter of C0-gamma-ray irradiation sterilization is: cobalt-60 irradiation 30 minutes, amount of radiation 8Kgy.
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Application publication date: 20111102