CN102210837A - Medicament for treating acquired immune deficiency syndrome (AIDS) - Google Patents

Medicament for treating acquired immune deficiency syndrome (AIDS) Download PDF

Info

Publication number
CN102210837A
CN102210837A CN2010101469530A CN201010146953A CN102210837A CN 102210837 A CN102210837 A CN 102210837A CN 2010101469530 A CN2010101469530 A CN 2010101469530A CN 201010146953 A CN201010146953 A CN 201010146953A CN 102210837 A CN102210837 A CN 102210837A
Authority
CN
China
Prior art keywords
radix
effect
rhizoma
fructus
herba
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2010101469530A
Other languages
Chinese (zh)
Inventor
肖嘉惠
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN2010101469530A priority Critical patent/CN102210837A/en
Publication of CN102210837A publication Critical patent/CN102210837A/en
Pending legal-status Critical Current

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides a completely oral medicament for treating acquired immune deficiency syndrome (AIDS), comprising the following components: hedyotis diffusa, honeysuckle, meadowrueleaf corydalis root, dandelion, weeping forsythia, asparagus, ophiopogon root, figwort root, fresh rehmannia root, peach kernel, chuanxiong rhizome, zedoary, achyranthes root, dahurian patrinia herb, giant knotweed, stiff silkworm, isatis root, white peony root, polygonatum, bitter caramon, mistletoe, tortoise plastron, glossy privet fruit, oyster, pollen, salvia miltiorrhiza, tree peony bark, bupleurum, bitter orange, cimicifuga foetida, dried orange peel, amomum fruit, officinal magnolia bark, rose, songaria cynomorium herb, self-heal, medicine terminalia fruit, gromwell, licorice, chrysanthemum, castor bean, bullfrog gallbladder, baikal skullcap root, medicated leaven, malt, rice sprout, chicken's gizzard-skin, radish seed, scorch-fried crataegus, Chinese yam, astragalus root, bighead atractylodes rhizome, sealwort, dangshen, prepared rehmannia root, cornus fruit, tuckahoe, jujube, Chinese wolfberry, cistanche, dragon bone, oyster, epimedium, curculigo root, deerhorn glue, ginseng, donkey-hide glue, white fungus, angelica, spatholobus stem and turtle shell. The medicament provided by the invention not only can cure AIDS and has good therapeutic effect on AIDS, but also can prevent infection of AIDS.

Description

The medicine of treatment acquired immune deficiency syndrome (AIDS)
Technical field
What the present invention relates to is a kind of Chinese medicine for the treatment of acquired immune deficiency syndrome (AIDS), according to the state of an illness dialectical execute to control comprise 3 kinds of oral medicine and 2 kinds of outer washing medicines.
Technical background
According to the popular status report of the United Nations whole world acquired immune deficiency syndrome (AIDS), the number of the infected of China rises to about 750,000 people in 2009 from about 450,000 of calendar year 2001.Mostly all be from the disease of having an injection, behaviors such as blood transfusion, sexual intercourse cause.Why do not have a kind of medicine so far and effect a radical cure acquired immune deficiency syndrome (AIDS)? because HIV is a kind of virus that can attack the human body viscera system.As target of attack, considerable damage T4 lymphoid tissue produces high fatefulue interior depleted T4 lymphoid tissue weight limit among the human immune system for it.This virus infects in the region throughout one's life, destroys people's immunologic balance, makes human body become the carrier of various diseases.HIV itself can't cause any disease, but after immune system was destroyed by HIV, human body was because resistivity is low excessively, and the chance of immunocyte is duplicated in forfeiture, thereby the disease that infects other causes various MOI and death.HIV (human immunodeficiency virus) (Human Immunodeficiency Virus) is people's intravital incubation period of average out to 12 to 13 years, developing into before the acquired immune deficiency syndrome (AIDS) patient, and patient's appearance looks normally, and they can be without any a lot of years of symptom ground live and work.Infect human HIV virus at present and mainly contain amphitypy: except that HIV-1, also have HIV-2.Scientists such as the special Neil of HIV-2 illiteracy found in the western acquired immune deficiency syndrome (AIDS) human body in Africa in nineteen eighty-three, the HIV virus type that its shape, effect, route of transmission, clinical manifestation are all found with nineteen eighty-three seemingly, therefore ICTV names the former and is HIV-1, and the latter names and is HIV-2.Though the numerous medical research personnel in the whole world have paid huge effort, do not develop the specific medicament of radical cure acquired immune deficiency syndrome (AIDS) so far as yet, not can be used for the effective vaccine that prevents yet.At present, this sick mortality rate almost up to 100% " super cancer ", is listed in the Class B Notifiable disease by China, and is listed in one of border monitoring of hygiene infectious disease.So we call it " super incurable disease ".
Summary of the invention
The medicine that the purpose of this invention is to provide a kind of energy treatment of AIDS.
Main formula medicine of the present invention has following grouping:
1, Herba Hedyotidis Diffusae 30, Flos Lonicerae 26, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 16, Herba Taraxaci 30, Fructus Forsythiae 20, Radix Asparagi 10, Radix Ophiopogonis 10, the bright Radix Rehmanniae 20, Radix Scrophulariae 15, Semen Persicae 12, Rhizoma Chuanxiong 9, Rhizoma Curcumae 15, Radix Achyranthis Bidentatae 12, pollen 16, Radix Salviae Miltiorrhizae 60, Cortex Moutan 10, Radix Bupleuri 10, Fructus Aurantii 12, Pericarpium Citri Reticulatae 10, Fructus Amomi 10, Cortex Magnoliae Officinalis 20, Flos Rosae Rugosae 12, Herba Cynomorii 10, Spica Prunellae 15, the Fructus Chebulae 10, Radix Arnebiae (Radix Lithospermi) 18, Radix Glycyrrhizae 12, Flos Chrysanthemi 12, Semen Ricini 1,6 in bull frog gallbladder, Radix Scutellariae 12, Massa Medicata Fermentata 15, Fructus Hordei Germinatus 20, Fructus Setariae Germinatus 20, Endothelium Corneum Gigeriae Galli 10, Semen Raphani 12, Rhizoma Dioscoreae 30, the Radix Astragali 18, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Polygonati 12, Radix Codonopsis 36, burnt short, bristly hair or beard 22, Poria 30,10 in Fructus Jujubae, Herba Cistanches 30, Radix Angelicae Sinensis 10, Caulis Spatholobi 15, Colla Corii Asini 16.
2, Herba Hedyotidis Diffusae 0.1-300, Flos Lonicerae 0.1-300, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.1-300, Herba Taraxaci 3-500, Fructus Forsythiae 3-300, Radix Asparagi 0.1-200, Radix Ophiopogonis 0.1-250, bright Radix Rehmanniae 0.1-300, Radix Scrophulariae 1-500, Semen Persicae 1-300, Rhizoma Chuanxiong 1-300, Rhizoma Curcumae 1-300, Radix Achyranthis Bidentatae 1-300, pollen 1-250, Radix Salviae Miltiorrhizae 0.1-900, Cortex Moutan 1-200, Radix Bupleuri 0.1-3000, Fructus Aurantii 1-300, Pericarpium Citri Reticulatae 0.1-300, Fructus Amomi 0.1-300, Cortex Magnoliae Officinalis 5-300, Flos Rosae Rugosae 1-200, Herba Cynomorii 0.1-300, Spica Prunellae 0.1-500, Fructus Chebulae 0.1-500, Radix Arnebiae (Radix Lithospermi) 1-500, Radix Glycyrrhizae 0.1-1000, Flos Chrysanthemi 0.1-1000, Semen Ricini 0.001-300, bull frog gallbladder 0.1-1180, Radix Scutellariae 0.1-300, Massa Medicata Fermentata 0.1-1400, Fructus Hordei Germinatus 0.1-1400, Fructus Setariae Germinatus .01-1400, Endothelium Corneum Gigeriae Galli 0.1-1200, Semen Raphani 0.1-1000, Rhizoma Dioscoreae 0.1-3000, Radix Astragali 0.1-2000, Rhizoma Atractylodis Macrocephalae 0.1-2000, Rhizoma Polygonati 0.1-2000, Radix Codonopsis 0.1-3000, burnt short, bristly hair or beard 0.01-2000, Poria 0.1-5000, Fructus Jujubae 0.01-2000, Herba Cistanches 0.1-1000, Radix Angelicae Sinensis 0.01-4000, Caulis Spatholobi 0.1-3000, Colla Corii Asini 0.1-400.
Traditional Chinese medical science prescription is separated: we have kidney invigorating and YANG supporting with Herba Cynomorii, bone and muscle strengthening, intestine moistening laxation and the active effect of anti-hiv protease; Spica Prunellae has heat-clearing and toxic substances removing, removing fire from the liver, and the effect of Disperse hepatic depression and tangible anti-HIV is so be principal agent.Use the Radix Codonopsis invigorating the spleen and replenishing QI, Radix Astragali tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, Rhizoma Dioscoreae tonifying the spleen and stomach, lung benefiting nourishing kidney, Rhizoma Atractylodis Macrocephalae spleen reinforcing dampness, Fructus Jujubae invigorating the spleen and replenishing QI, Poria spleen invigorating mind calming, Rhizoma Polygonati spleen reinforcing lung moistening, Radix Achyranthis Bidentatae the kidney invigorating bone and muscle strengthening; Chinese angelica blood supplementing is invigorated blood circulation, the intestine moistening laxation, and the Colla Corii Asini nourishing blood hemostasis, nourishing YIN and moistening the lung, Caulis Spatholobi is enriched blood and invigorates blood circulation, and channels sootheing and network vessel quickening helps the Herba Cynomorii kidney invigorating and YANG supporting, strengthening the tendons and bones, the YIN nourishing intestine moistening improves the body and culature, and increases immunity, so be accessory drugs.Rush down the poisoning HIV (human immunodeficiency virus) of going out with Semen Ricini, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae), Flos Chrysanthemi, Radix Arnebiae (Radix Lithospermi), Radix Scutellariae, Flos Rosae Rugosae help the Spica Prunellae heat-clearing and toxic substances removing, and dispersing swelling and dissipating binds is killed various bacteria virus and HIV, so be accessory drugs.Reduce phlegm Radix Bupleuri elevate a turnable ladder yang-energy, reducing fever by reconciliation with Fructus Aurantii promoting the circulation of QI, removing food stagnancy, dispersing the stagnated live-QI to relieve the stagnation of QI, Pericarpium Citri Reticulatae, Fructus Amomi are regulated the flow of vital energy, appetite-stimulating indigestion-relieving, and the Cortex Magnoliae Officinalis dampness therapeutic method to keep the adverse QI flowing downwards is loose full, rhizoma sparganic, the circulation of qi promoting of Rhizoma Curcumae removing blood stasis, the removing food stagnancy pain relieving, Semen Persicae, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae, the pain relieving of Cortex Moutan blood circulation promoting competent silt, the capable then blood of gas is capable, and systemic blood is unobstructed, assistant helps nutrition, medicine to move whole body and play better therapeutical effect, so be adjuvant drug.Protect the liver with bull frog gallbladder function of gallbladder promoting, Fructus Hordei Germinatus, Fructus Setariae Germinatus, Endothelium Corneum Gigeriae Galli, Semen Raphani, long-pending, the strengthening the spleen and stomach of hawthorn digesting, assistant helps the intestines and stomach to absorb more nutrition, in case become thin, builds up resistance.Concoct all medicines with Radix Glycyrrhizae, benefiting vital QI and blood is killed HIV (human immunodeficiency virus), can prevent the lymphoid tissue among the HIV (human immunodeficiency virus) destruction human immune system especially, and treatment of AIDS.
The present invention has added medicines such as Caulis Perillae, Herba Schizonepetae, Herba Menthae, Radix Gentianae Macrophyllae, the Radix Angelicae Dahuricae, Radix Asteris, Bulbus Fritillariae Uninbracteatae, Radix Platycodonis on the basis of main formula, sense just of treatment acquired immune deficiency syndrome (AIDS) and acquired immune deficiency syndrome (AIDS) have heating, general pain, and cough, the effect of pharyngalgia, medicine has following grouping:
1, Herba Hedyotidis Diffusae 30, Flos Lonicerae 26, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 16, Herba Taraxaci 30, Fructus Forsythiae 20, Radix Asparagi 10, Radix Ophiopogonis 10, the bright Radix Rehmanniae 20, Radix Scrophulariae 15, Semen Persicae 12, Rhizoma Chuanxiong 9, Rhizoma Curcumae 15, Radix Achyranthis Bidentatae 12, pollen 16, Radix Salviae Miltiorrhizae 60, Cortex Moutan 10, Radix Bupleuri 10, Fructus Aurantii 12, Pericarpium Citri Reticulatae 10, Fructus Amomi 10, Cortex Magnoliae Officinalis 20, Flos Rosae Rugosae 12, Herba Cynomorii 10, Spica Prunellae 15, the Fructus Chebulae 10, Radix Arnebiae (Radix Lithospermi) 18, Radix Glycyrrhizae 12, Flos Chrysanthemi 12, Semen Ricini 1,6 in bull frog gallbladder, Radix Scutellariae 12, Massa Medicata Fermentata 15, Fructus Hordei Germinatus 20, Fructus Setariae Germinatus 20, Endothelium Corneum Gigeriae Galli 10, Semen Raphani 12, Rhizoma Dioscoreae 30, the Radix Astragali 30, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Polygonati 12, Radix Codonopsis 36, burnt short, bristly hair or beard 22, Poria 30,10 in Fructus Jujubae, Herba Cistanches 10, Radix Angelicae Sinensis 10, Caulis Spatholobi 15, Colla Corii Asini 16.
Caulis Perillae 10, Herba Schizonepetae 10, Herba Menthae 10, Radix Gentianae Macrophyllae 12, the Radix Angelicae Dahuricae 8, Radix Asteris 10, Bulbus Fritillariae Uninbracteatae 10, Radix Platycodonis 10.
2, Herba Hedyotidis Diffusae 0.1-300, Flos Lonicerae 0.1-300, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.1-300, Herba Taraxaci 3-500, Fructus Forsythiae 3-300, Radix Asparagi 0.1-200, Radix Ophiopogonis 0.1-250, bright Radix Rehmanniae 0.1-300, Radix Scrophulariae 1-500, Semen Persicae 1-300, Rhizoma Chuanxiong 1-300, Rhizoma Curcumae 1-300, Radix Achyranthis Bidentatae 1-300, pollen 1-250, Radix Salviae Miltiorrhizae 0.1-900, Cortex Moutan 1-200, Radix Bupleuri 1-300, Fructus Aurantii 1-300, Pericarpium Citri Reticulatae 0.1-300, Fructus Amomi 0.1-300, Cortex Magnoliae Officinalis 5-300, Flos Rosae Rugosae 1-200, Herba Cynomorii 0.1-300, Spica Prunellae 0.1-500, Fructus Chebulae 0.1-500, Radix Arnebiae (Radix Lithospermi) 1-500, Radix Glycyrrhizae 0.1-1000, Flos Chrysanthemi 0.1-1000, Semen Ricini 0.001-300, bull frog gallbladder 0.1-1180, Radix Scutellariae 0.1-300, Massa Medicata Fermentata 0.1-1400, Fructus Hordei Germinatus 0.1-1400, Fructus Setariae Germinatus .01-1400, Endothelium Corneum Gigeriae Galli 0.1-1200, Semen Raphani 0.1-1000, Rhizoma Dioscoreae 0.1-3000, Radix Astragali 0.1-2000, Rhizoma Atractylodis Macrocephalae 0.1-2000, Rhizoma Polygonati 0.1-2000, Radix Codonopsis 0.1-3000, burnt short, bristly hair or beard 0.01-2000, Poria 0.1-5000, Fructus Jujubae 0.01-2000, Herba Cistanches 0.1-1000, Radix Angelicae Sinensis 0.01-4000, Caulis Spatholobi 0.1-3000, Colla Corii Asini 0.1-400.
Caulis Perillae 1-100, Herba Schizonepetae 1-100, PUHE 1-100, Radix Gentianae Macrophyllae 1-100, Radix Angelicae Dahuricae 1-100, Radix Asteris 0.1-50, Bulbus Fritillariae Uninbracteatae 0.1-30, Radix Platycodonis 3-30.
The side separates: sense just sees Table the disease person for HIV (human immunodeficiency virus), on 1 side's basis, adds Caulis Perillae and delivers cold expelling, and the chest stuffiness relieving of regulating the flow of vital energy is separated the miasma poison, ends vomiting uncomfortable in chest; Herba Schizonepetae is dispeled the wind and delivers, and separates a body and has sore throat, and ends skin skin ulcer rash pruritus; Herba Menthae Pulvis Diaphoreticus wind heat, the pharyngalgia of dispelling conjunctival congestion is ended the whole body pruritus; The Radix Angelicae Dahuricae is delivered to dispel the wind and is ended headache, and sore swollen toxin is controlled in evacuation of pus and Radix Gentianae Macrophyllae removes rheumatic arthralgia, moves back the hectic fever due to YIN-deficiency brain fever, the insertion tendon whole body pain of relaxing; Radix Asteris, Bulbus Fritillariae Uninbracteatae, Radix Platycodonis nourishing the lung to keep the adverse QI downward, dissipating depression of QI eliminating stagnation, lung qi dispersing cough-relieving, pharynx-clearing throat-benefiting.So play better action.
The present invention has added medicines such as Carapax et Plastrum Testudinis, Carapax Trionycis, Radix Rehmanniae Preparata, Fructus Corni, Fructus Lycii, Herba Epimedii, Rhizoma Curculiginis, Colla cornus cervi, Fructus Alpiniae Oxyphyllae, Herba Taxilli, Radix Ginseng, the Radix Paeoniae Alba, Rhizoma Polygonati Odorati, Fructus Ligustri Lucidi, Tremella, Rhizoma Cimicifugae, Os Draconis, Concha Ostreae, Radix Isatidis, tiger zhang, Herba Patriniae, Bombyx Batryticatus on the basis of main formula, played enhancing immunity, strengthened function of detoxification, hard masses softening and resolving, remove the relieving convulsion effect of wind, and thoroughly cure HIV, medicine has following grouping:
1, Herba Hedyotidis Diffusae 30, Flos Lonicerae 26, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 16, Herba Taraxaci 30, Fructus Forsythiae 20, Radix Asparagi 10, Radix Ophiopogonis 10, the bright Radix Rehmanniae 20, Radix Scrophulariae 15, Semen Persicae 12, Rhizoma Chuanxiong 9, Rhizoma Curcumae 15, Radix Achyranthis Bidentatae 12, pollen 16, Radix Salviae Miltiorrhizae 60, Cortex Moutan 10, Radix Bupleuri 10, Fructus Aurantii 12, Pericarpium Citri Reticulatae 10, Fructus Amomi 10, Cortex Magnoliae Officinalis 20, Flos Rosae Rugosae 12, Herba Cynomorii 10, Spica Prunellae 15, the Fructus Chebulae 10, Radix Arnebiae (Radix Lithospermi) 18, Radix Glycyrrhizae 12, Flos Chrysanthemi 12, Semen Ricini 1,6 in bull frog gallbladder, Radix Scutellariae 12, Massa Medicata Fermentata 15, Fructus Hordei Germinatus 20, Fructus Setariae Germinatus 20, Endothelium Corneum Gigeriae Galli 10, Semen Raphani 12, Rhizoma Dioscoreae 30, the Radix Astragali 18, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Polygonati 12, Radix Codonopsis 36, burnt short, bristly hair or beard 22, Poria 30,10 in Fructus Jujubae, Herba Cistanches 30, Radix Angelicae Sinensis 10, Caulis Spatholobi 15, Colla Corii Asini 16.
Carapax et Plastrum Testudinis 30, Carapax Trionycis 30, Radix Rehmanniae Preparata 16, Fructus Corni 12, Fructus Lycii 10, Herba Epimedii 12, Rhizoma Curculiginis 20, Colla cornus cervi 12, Fructus Alpiniae Oxyphyllae 10, Herba Taxilli 10, Radix Ginseng 10, the Radix Paeoniae Alba 12, Rhizoma Polygonati Odorati 12, Fructus Ligustri Lucidi 15, Tremella 30, Rhizoma Cimicifugae 12, Os Draconis 26, Concha Ostreae 30, Radix Isatidis 12, tiger zhang 18, Herba Patriniae 20, Bombyx Batryticatus 15.
2, Herba Hedyotidis Diffusae 0.1-300, Flos Lonicerae 0.1-300, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.1 300, Herba Taraxaci 3-500, Fructus Forsythiae 3-300, Radix Asparagi 0.1-200, Radix Ophiopogonis 0.1-250, bright Radix Rehmanniae 0.1-300, Radix Scrophulariae 1-500, Semen Persicae 1-300, Rhizoma Chuanxiong 1-300, Rhizoma Curcumae 1-300, Radix Achyranthis Bidentatae 1-300, pollen 1-250, Radix Salviae Miltiorrhizae 0.1-900, Cortex Moutan 1-200, Radix Bupleuri 1-300, Fructus Aurantii 1-300, Pericarpium Citri Reticulatae 0.1-300, Fructus Amomi 0.1-250, Cortex Magnoliae Officinalis 5-300, Flos Rosae Rugosae 1-20, Herba Cynomorii 0.1-300, Spica Prunellae 0.1-500, Fructus Chebulae 0.1-500, Radix Arnebiae (Radix Lithospermi) 1-500, Radix Glycyrrhizae 0.1-100, Flos Chrysanthemi 0.11000, Semen Ricini 0.001-300, bull frog gallbladder 0.1-1180, Radix Scutellariae 0.1-300, Massa Medicata Fermentata 0.1-1400, Fructus Hordei Germinatus 0.1-1400, Fructus Setariae Germinatus .01-1400, Endothelium Corneum Gigeriae Galli 0.1-1200, Semen Raphani 0.1-1000, Rhizoma Dioscoreae 0.1-3000, Radix Astragali 0.1-2000, Rhizoma Atractylodis Macrocephalae 0.1-2000, Rhizoma Polygonati 0.1-2000, Radix Codonopsis 0.1-3000, burnt short, bristly hair or beard 0.01-2000, Poria 1-200, Fructus Jujubae 0.01-2000, Herba Cistanches 1-100, Radix Angelicae Sinensis 0.01-4000, Caulis Spatholobi 0.1-3000, Colla Corii Asini 0.1-400.
Carapax Trionycis 1-200, Radix Rehmanniae Preparata 1-100, Fructus Corni 1-100, Tremella 1-100, Fructus Lycii 1-100, Os Draconis 1-100, Concha Ostreae 1-100, Herba Epimedii 1-200, Rhizoma Curculiginis 1-100, Colla cornus cervi 1-100, Radix Ginseng 1-200, Herba Patriniae 1-2000, tiger zhang 1-500, Bombyx Batryticatus 1-200, Radix Isatidis 1-1000, Radix Paeoniae Alba 1-200, Rhizoma Polygonati Odorati 1-200, Fructus Alpiniae Oxyphyllae 1-200, Herba Taxilli 1-100, Carapax et Plastrum Testudinis 1-100, Fructus Ligustri Lucidi 1-100, Concha Ostreae 3-60, Rhizoma Cimicifugae 2-300.
The side separates: on 1 side's basis, added the smart hemostasis of Cornu Cervi gummed, hemostasis; Herba Epimedii, Rhizoma Curculiginis kidney invigorating and YANG supporting, wind-damp dispelling; Fructus Alpiniae Oxyphyllae the kidney invigorating warming the spleen, the effect of Herba Taxilli invigorating kidney-YANG, strengthening the spleen kidney, complement sun; The Carapax et Plastrum Testudinis strengthening the tendons and bones, enriching yin and nourishing kidney, Carapax Trionycis YIN nourishing, clots absorbing, the emblem that disappears, the Radix Rehmanniae Preparata kidney nourishing and replenishing vital essence is enriched blood, tonifying blood and arresting bleeding and the Kidney-Yin effect of benefit, Fructus Corni, Fructus Lycii the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, arresting seminal emission hidroschesis; As above two groups of medicines can lead to Kidney-Yin, the Yuanyang of conception vessel and governor vessel benefit.The Radix Ginseng strengthening QI of middle-JIAO, big vigour, promoting the production of body fluid to quench thirst, the Radix Paeoniae Alba yin nourishing of enriching blood, suppressing the hyperactive liver pain relieving, the Rhizoma Polygonati Odorati nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst, the Fructus Ligustri Lucidi nourishing the liver and kidney, crow must make eye bright, Tremella tonifying YIN blood, born fluid, the Rhizoma Cimicifugae detoxifcation rises healthy energy, and it is astringent or styptic treatment for spontaneous sweating that Os Draconis are relieving convulsion, suppressing the hyperactive liver and subsiding YANG, the Concha Ostreae suppressing the hyperactive liver and subsiding YANG, tranquillization with heavy prescription, hard masses softening and resolving is restrained astringent or styptic treatment for spontaneous sweating, the Radix Isatidis clearing away heat and cooling blood, resolving toxin and disinhibiting the throat, Herba Patriniae heat-clearing and toxic substances removing, clots absorbing evacuation of pus, tiger zhang blood circulation promoting and blood stasis dispelling, the dampness removing jaundice eliminating, Bombyx Batryticatus is expellingged wind and relieving convulsion, dissipating phlegm and resolving masses.Increase by 1 side's various effects, be used for the acquired immune deficiency syndrome (AIDS) anaphase more, played the effect of satisfied treatment of AIDS.
The present invention has also created cold and cool property washout 1 side's medicine for the treatment of serious hot and humid ecchymosis, purpose is to absorb the drug from whole skin to enter grandson's network, venation until heart, can replenish these position efficacy of a drug deficiencies and play the effect that HIV (human immunodeficiency virus) is killed in inside and outside pincer attack, medicine comprises following component:
1, Radix Et Rhizoma Rhei 100, Flos Rosae Rugosae 100, pollen 200, Flos Chrysanthemi 160, Spica Prunellae 80, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 60,30 in bull frog gallbladder, Cortex Phellodendri 70, Radix Scutellariae 60, Rhizoma Coptidis 60, Fructus Gardeniae 60, Flos Lonicerae 100, Radix Sophorae Flavescentis 70, Rhizoma Smilacis Glabrae 60, tiger zhang 60, Herba Violae 100, Fructus Forsythiae 70g, Radix Sophorae Tonkinensis 60, white portion 100, Rhizoma Paridis 100, Herba Scutellariae Barbatae 50, Rhizoma Osmundae 50, Oldenlandia diffusa Roxb 150, Herba Solani Lyrati 130, Radix Saposhnikoviae 60, larval moult 60, Herba Schizonepetae 60, the Radix Angelicae Dahuricae 30, Camphora 1, Borneolum Syntheticum 1, Spina Gleditsiae 60, Flos Caryophylli 60.
2, Radix Et Rhizoma Rhei 1-500, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 1-200, Spica Prunellae 1-500, Flos Rosae Rugosae 1-200, pollen 1-400, Flos Chrysanthemi 1-300, bull frog gallbladder 0.1-180, Cortex Phellodendri 1-300, Radix Scutellariae 1-300, Rhizoma Coptidis 1-200, Fructus Gardeniae 1-200, Flos Lonicerae 1-500, Radix Sophorae Flavescentis 1-200, Rhizoma Smilacis Glabrae 1-100, tiger zhang 1-200, Herba Violae 1-300, Fructus Forsythiae 1-200, Radix Sophorae Tonkinensis 1-300, the white 1-300 of portion, Rhizoma Paridis 1-200, Herba Scutellariae Barbatae 1-500, Rhizoma Osmundae 1-200, Oldenlandia diffusa Roxb 1-300, Herba Solani Lyrati 1-300, Spina Gleditsiae 1-300, Radix Saposhnikoviae-200, larval moult 1-200, Herba Schizonepetae 1-200, Radix Angelicae Dahuricae 1-100, Camphora 0.1-100, Borneolum Syntheticum 0.1-100, Flos Caryophylli 1-300.
The side separates: this washout side attacks stagnant, clearing away damp-heat with Radix Et Rhizoma Rhei, pathogenic fire purging poison, removing heat from blood, blood stasis dispelling; The Flos Rosae Rugosae soothing liver-QI for relieving depression is amusing in the accent; The pollen clearing heat and relieving fidgetness, promoting the production of body fluid to quench thirst; The chrysanthemum powder forimproving wind heat, suppressing the hyperactive liver makes eye bright, detoxifcation; The Spica Prunellae clearing away liver-fire, Disperse hepatic depression; The clear gesture of Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) is moved back hectic fever due to YIN-deficiency; Bull frog gallbladder, Cortex Phellodendri, Rhizoma Coptidis, the clear gesture dampness of Radix Scutellariae, antiabortive, nourishing YIN to lower pathogenic fire, poison falls in pathogenic fire purging; Fructus Gardeniae, Flos Lonicerae, Rhizoma Smilacis Glabrae, tiger zhang, Rhizoma Paridis, Herba Scutellariae Barbatae, Rhizoma Osmundae, Oldenlandia diffusa Roxb, Herba Violae, Fructus Forsythiae, Radix Sophorae Tonkinensis heat-clearing and toxic substances removing, diuresis of blood circulation promoting, eliminating carbuncle eliminating stagnation, reducing swelling and alleviating pain; The Herba Solani Lyrati heat-clearing and toxic substances removing, killing parasites for relieving itching, easing joint movement; Radix Saposhnikoviae is delivered, and dispels the wind, wins wet; The larval moult wind heat of loosing, rash, arresting convulsion; The Radix Angelicae Dahuricae, Herba Schizonepetae are dispeled the wind and deliver, the evacuation of pus pain relieving; The clear gesture dehumidifying of Radix Sophorae Flavescentis, parasite killing detoxifcation, diuresis; White portion nourishing the lung to arrest cough, the parasite killing delousing; The Fructus Quisqualis destroying parasites for curing malnutrition has killing action to multiple parasite, and as above medicine is killed various bacteria, virus, fungus and antidotal common feature in addition.Too cold and cool for preventing the property of medicine, so add the property of Flos Caryophylli with warm cold relieving cold.Add Camphora and Borneolum Syntheticum inducing resuscitation, the clearing away heat to improve acuity of vision priming gos deep into playing in the body the satisfied effect of killing HIV (human immunodeficiency virus) in from the body surface to the body.
The invention the treatment stagnation of QI-blood, spleen-kidney vacuity cold, the wind and cold noxious dampness, cureless washout 2 side's medicines have following grouping:
1, Radix Aconiti Lateralis Preparata 100, Flos Caryophylli 90, Realgar 80, Fructus Piperis 50, Rhizoma Arisaematis 90, Rhizoma Pinelliae 90, Oletum Trogopterori 90, TOUGEYAO 30, Cortex Cinnamomi 60, Radix Aconiti 50, Radix Aconiti Kusnezoffii 50, Rhizoma Alpiniae Officinarum 90, Herba Cynomorii 200, the Fructus Chebulae 200, Semen Ricini 60, Radix Angelicae Sinensis 100, Ramulus Cinnamomi 120, Rhizoma Curcumae Longae 80, Olibanum 50, Myrrha 50, Cortex Magnoliae Officinalis 90, Rhizoma Atractylodis 90, Radix Saposhnikoviae 90, Herba Schizonepetae 90, larval moult 60, the Radix Angelicae Dahuricae 90, the Radix Aucklandiae 90, Fructus Citri 90, Styrax 100, Fructus Arctii 100, Helwingia himalaica 90, Herba Ainsliaea Albotomentosae 90, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 60, Rhizoma Paridis 80, Rhizoma Acori Graminei 80, Rhizoma Chuanxiong 90, Fructus Gleditsiae Abnormalis 50, Herba Ephedrae 90, Herba Asari 80, Pheretima 90, Bombyx Batryticatus 80, Flos Rosae Rugosae 160, pollen 150, Flos Chrysanthemi 160, Spica Prunellae 160, Radix Paeoniae Rubra 60, Radix Et Rhizoma Rhei 80, Camphora 5, Borneolum Syntheticum 10.
2, Radix Aconiti Lateralis Preparata 1-400, Flos Caryophylli 1-300, Realgar 1-200, Fructus Piperis 1-300, Rhizoma Arisaematis 1300, Rhizoma Pinelliae 1-300, Oletum Trogopterori 1-100, TOUGEYAO 1-300, Cortex Cinnamomi 1-500, Radix Aconiti 1-300, Radix Aconiti Kusnezoffii 1-300, Rhizoma Alpiniae Officinarum 1-500, Herba Cynomorii 1-1000, Fructus Chebulae 1-1000, Semen Ricini 1-1000, Radix Angelicae Sinensis 1-400, Ramulus Cinnamomi 1-500, Rhizoma Curcumae Longae 1-400, Olibanum 1-300, Myrrha 1-100, Cortex Magnoliae Officinalis 1-500, Rhizoma Atractylodis 1-300, Radix Saposhnikoviae 1-400, Herba Schizonepetae 1-300, larval moult 1-300, Radix Angelicae Dahuricae 1-300, Radix Aucklandiae 1-400, Fructus Citri 1-400, Styrax 1-500, Fructus Arctii 1-400, Helwingia himalaica 1-300, Herba Ainsliaea Albotomentosae 1-300, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 1-300, Rhizoma Paridis 1-200, Rhizoma Acori Graminei 1-200, Rhizoma Chuanxiong 1-300, Fructus Gleditsiae Abnormalis 1-350, Herba Ephedrae 1-500, Herba Asari 1-300, Pheretima 1-300, Bombyx Batryticatus 1-300, Flos Rosae Rugosae 1-1000, pollen 1-1500, Flos Chrysanthemi 1-1000, Spica Prunellae 1-1500, Radix Paeoniae Rubra 1-300, Radix Et Rhizoma Rhei 1-400, Camphora 1-200, Borneolum Syntheticum 1-100.
The side separates: we are used for the disease of cold and cool weakness and have a bath.The patient belongs to the body of cold and cool weakness, so use the Radix Aconiti Lateralis Preparata warming the kidney, recuperating depleted YANG is mended fire, and dispersing cold for relieving pain can be removed the loss of YANG due to profuse perspiration due to the HIV, and extremity are fainted contrary, anemofrigid-damp arthralgia, and coldness and pain in the epigastrium, edema due to deficiency of the kidney, and increase immunity; Flos Caryophylli stomach warming sending down the abnormal ascending QI is dispeled cold syndrome of the stomach, vomiting, singultus, breast abdomen cold type of pain, can remove the intestines and stomach deficiency-cold symptoms that HIV causes; It is supporing yang that Realgar energy parasite killing is mended fire, can dispel HIV and cause various skin diseases such as itching over the body cold skin; Fructus Piperis energy warming spleen and stomach for dispelling cold, the supporing yang danger of holding up can be removed the coldness and pain in the epigastrium that HIV causes, and cold syndrome of the stomach is vomited and diarrhoea and is caused very fast becoming thin; The Rhizoma Arisaematis rheumatism that HIV causes of dispelling, spasm, phlegm retention, epilepsy; The Rhizoma Pinelliae drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, removing expands disappears expires; The Oletum Trogopterori promoting blood circulation and hemostasis, blood-activating analgetic, removing food stagnancy detoxifcation; TOUGEYAO (medical herbs of Yi Autonomous Prefecture of Liangshan) energy blood circulation promoting and blood stasis dispelling, warming the meridian and promoting blood circulation, the long-pending tissue regeneration promoting of dispelling, removing damp and stopping pain; It is supporing yang that Cortex Cinnamomi is mended fire, dispersing cold for relieving pain, warming the meridian and promoting blood circulation; Radix Aconiti Kusnezoffii, Radix Aconiti, Rhizoma Alpiniae Officinarum, expelling wind and removing dampness, dispelling cold by warming the meridian, dispersing cold for relieving pain is dispeled numb limbs and tense tendons, because of the deficiency of YIN carbuncle that breast abdomen cold type of pain causes, the hemiplegia that migratory arthralgia causes; Herba Cynomorii tonifying YANG controlling nocturnal emission with astringent drugs, strong muscle nourishes blood; Fructus Chebulae's astringing intestine to stop diarrhea therapeutic method to keep the adverse QI flowing downwards, the sore-throat relieving of astringing the lung; Semen Ricini is drawn out pus by applying a plaster to the affected part, intestinal stasis relieving, the sharp key of collateral dredging; The circulation of qi promoting of Rhizoma Curcumae Longae removing blood stasis, inducing menstruation to relieve menalgia; The Olibanum blood circulation promoting regulates qi, the pain relieving granulation promoting; The Myrrha blood stasis dispelling, detumescence, analgesic therapy; Chinese angelica blood supplementing is invigorated blood circulation, and menstruction regulating and pain relieving is moisturized laxation; The Ramulus Cinnamomi expelling cold and relieving exterior syndrome, warming the meridian activates yang; Cortex Magnoliae Officinalis circulation of qi promoting intestinal stasis relieving, dampness, lowering the adverse QI to relieve asthma; Rhizoma Atractylodis are drying damp and strengthening spleen, diaphoresis; Radix Saposhnikoviae is delivered, and dispels the wind, and wins wet; Herba Schizonepetae is dispeled the wind and delivers; The larval moult wind heat of loosing, rash, arresting convulsion; The Herba Ephedrae diaphoresis is relievingd asthma, diuretic; Herba Asari is delivered diffusing wind, wind-expelling pain-stopping, warming the lung to eliminate phlegm; The Radix Angelicae Dahuricae is delivered and is dispeled the wind, the evacuation of pus pain relieving; Radix Aucklandiae promoting the circulation of QI to relieve pain, to the chest and abdomen swelling and pain that causes because of HIV, vomiting dysentery, hernia stomachache has better curative effect; The Fructus Citri depressed liver-energy dispersing and QI regulating, preventing or arresting vomiting reduces phlegm; The Styrax inducing resuscitation is warded off dirty reducing phlegm; The hot perfume (or spice) of Rhizoma Acori Graminei is regulated the flow of vital energy, and has one's ideas straightened out that it is dirty to ward off, and it is wet to reduce phlegm, and can dispel the syncope due to accumulation of phlegm epilepsy that causes because of HIV, and sudden syncope is fainted; Rhizoma Chuanxiong has blood-activating and qi-promoting, wind-expelling pain-stopping, the effect of row's meridian and relieving pain; The Radix Paeoniae Rubra removing heat from blood and promoting blood circulation, removing fire from the liver, carbuncle looses; Fructus Gleditsiae Abnormalis eliminates the phlegm and has one's ideas straightened out, mass dissipating and swelling eliminating; Pheretima is ended stem and relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and collateral dredging is relievingd asthma, to the swollen ulcer drug that HIV causes, and the dizzy better curative effect that has of having a headache; Bombyx Batryticatus is expellingged wind and relieving convulsion, dissipating phlegm and resolving masses, resolving toxin and disinhibiting the throat; The Flos Rosae Rugosae dispersing the stagnated live-QI to relieve the stagnation of QI is amusing in the accent; The pollen clearing heat and relieving fidgetness, promoting the production of body fluid to quench thirst; Flos Chrysanthemi dispelling wind suppressing the hyperactive liver, liver heat removing and eyesight improving, skin ulcer is treated in detoxifcation; The Spica Prunellae clearing away liver-fire, Disperse hepatic depression is killed various bacteria virus and HIV, is anti-hot exaggerating, with the Radix Et Rhizoma Rhei poison that purges heat, blood stasis dispelling blood; Add the effect that Camphora, Borneolum Syntheticum priming go deep into playing in the body better treatment acquired immune deficiency syndrome (AIDS).
Modern medicine study proves:
Flos Rosae Rugosae: (1) reduces the amplitude that the ischemic ECG ST section is raised to cardiovascular system and the microcirculatory rose wate that influences, myocardial ischemia sexually revises due to the antagonism isoproterenol, improve the superoxide dismutase activity of ischemic myocardium, suppress the release of creatine kinase.The local dropping of Flos Rosae Rugosae total extract can increase the arteriolar blood flow rate of mesentery, accelerates the different recovery that causes microcirculation disturbance of epinephrine.Tannin E lures different platelet aggregation, and tannin E platelet may be the adp receptor agonist.(2). other effect Flos Rosae Rugosae extracts all have antivirus action to epidemic disease defective virus, leucovirus and T chronic myeloid leukemia virus.Its contained long aristin that obstructs has inhibitory action with the plain I of new suona horn to the reverse transcriptase that infects the leucovirus cell, energy antioxidation, removing DPPH free radical.Leukemia HL-60 cell is lured different differentiation, also suppress various tumor cell strains.
Herba Cynomorii: to Immune Effects, remove free radical, antiplatelet aggregation, have saccharide 17-hydroxy-11-dehydrocorticosterone sample effect Herba Cynomorii and can exempt from into human body cell regeneration and metabolism, the enhance immunity conditioning function has tangible anti-cancer, antiviral and function in delaying senility.
Spica Prunellae: the effect Spica Prunellae to cardiovascular system can reduce ARR incidence rate, myocardial infarct size is had dwindle, and reduces Infant Mortality, to myocardial protective effect. (2) antiinflammatory and immunosuppressive action.(3) hypoglycemic activity.(4) antibiotic, antivirus action all has inhibitory action in various degree to dysentery bacterium, vibrio cholera, Bacillus typhi, escherichia coli, Bacillus proteus, staphylococcus and Bacillus tuberculosis; Prunellin has obvious anti-AIDS toxic action.(5) lung tumor cell had significant cytotoxicity.
The Fructus Chebulae: (1) antioxidation Fructus Chebulae has scavenging action to active oxygen.The alcohol extract effect is stronger than extract.It can obviously be removed riboflavin and add crossing the gas oxygen anion and resisting the haemolysis that H2O2 causes of light generation.(2) other effect Fructus Chebulaes, terminalia flesh decoct all have obvious inhibitory action external to dysentery bacterium, Bacillus typhi, Pseudomonas aeruginosa, Bacillus proteus, staphylococcus aureus, Streptococcus hemolyticus, streptococcus pneumoniae and diphtheria corynebacterium, and smooth muscle is had spasmolysis.Radix Arnebiae (Radix Lithospermi): (1) antiinflammatory action shikonin can suppress the inductive foot swelling of carrageenin, and expression and the protein of the synthetic and TNF-amRNA of prostaglandin generate.(2) the antitumor action shikonin can suppress the propagation of squamous cell carcinoma and the activation of the inductive Epstein-Barr virus of inhibition tumor promoter TPA, causes malignant melanoma cell Cycle Arrest and apoptosis.(3) antifertility, the alkanol that influences in the effect Radix Arnebiae (Radix Lithospermi) of reproductive system have anti-implantation, antiearly pregnancy effect; Can suppress follicular development with ripe, reduce the concentration of serum follicule-stimulating hormone (FSH) and lutropin and the function of chorionic villi secretion HCG, destroy the chorionic villi structure.(4) alkanol to the effect Radix Arnebiae alcohol of dermatosis has inhibitory action to the epidermis cell hyper-proliferative that psoriasis causes.(5) resisting pathogenic microbes effect acetylshikonin has inhibitory action to staphylococcus aureus, escherichia coli, infection of staphylococcus aureus is had protective effect, and herpes simplex virus is had lethal effect; Can suppress inductive cytopathy of immunodeficiency virus (HIV-1) and chemokine receptor function.Function of resisting hepatitis C virus is arranged.(6) other effect Radix Arnebiae (Radix Lithospermi)s how the anthracene of quinone can prevent hepatic injury, improve the survival rate of poisoning by acetaminophen; Hypoglycemic activity is arranged, phagocytosis of macrophages is arranged, increase lymphocytic counting of T and function in the spleen, promote delayed allergy.Can reduce whole blood viscosity, improve fibrinogen content.And the platelet aggregation of collagen, arachidonic acid, ADP, platelet activating factor and thrombin induction there is inhibitory action.The effect removing heat from blood and promoting blood circulation, the detoxifcation rash cures mainly haematemesis, epistaxis, hematuria, purpura, macule, measles, jaundice, carbuncle is scalded.
Radix Glycyrrhizae: the Glycyrrhiza glabra L. in (1) anti-microbial effect Radix Glycyrrhizae is fixed, Glycyrrhiza glabra L. is plain, the licochalcone A of Glycyrrhiza inflata Bat. etc. can suppress common and the Drug resistance Helicobacter pylori, and the licorice extract vitro inhibition suppresses escherichia coli, staphylococcus aureus, Pseudomonas aeruginosa, group B streptococcus etc.Angelica Polysaccharide vitro inhibition vesicular stomatitis virus, I type herpes simplex virus and vaccinia virus.The hot water extract of Radix Glycyrrhizae has insecticidal action to clonorchis sinensis.(2) adrenal hormone sample effect Glycyrrhiza glabra L. lyophilization water extract can suppress adrenal gland-hypophysis cerebri s function, and promotes the kidney feritin to produce; The amycin nephropathy there is adrenal cortex feedback suppression phenomenon due to the exogenous 17-hydroxy-11-dehydrocorticosterone of antagonism.(3) arrhythmia and the calcium chloride and the AF that the acetylcholine mixed liquor brings out that the flavones ingredients such as effect liquirtin of cardio-cerebrovascular antagonism aconitine, barium chloride, ligation ramus descendens anterior arteriae coronariae sinistrae are brought out, the effect that has negativity frequency and negativity to conduct; Enoxolone has the agonist-like effect of Angiotensin II AT1 receptor.Glycyrrhiza glabra L. can reduce cholesterol and blood fat such as serum, liver, improves content of phospholipid, and glycyrrhizin can prolong blood plasma recalcification time etc., anticoagulant.(4) to the effect of digestive system 1. to the influencing the Radix Glycyrrhizae ethanol extraction and can suppress Semen Ricini oiliness diarrhoea, water logging stress ulcer and hydrochloric acid ulcer of gastrointestinal, pancreatic function, increase bile flow; Can improve the discharge of secretin concentration and pancreas in the blood; Suppress duodenum and jejunum contractile response that bethanechol causes.2. hepatoprotective effect can suppress carbon tetrachloride and alcohol induced liver fat degeneration and hepatic fibrosis, and hepatic injury is had protective effect.(5) antiinflammatory, antitussive, phlegm-dispelling functions Monosodium glycyrrhetin and Radix Glycyrrhizae acid amide can suppress granuloma induced by implantation of cotton pellets, sufficient sole of the foot Ovum Gallus domesticus album inflammation respectively, histamine causes the rising of capillary of skin permeability and the pleura inflammation due to the carrageenin is oozed out, eosinophilic granulocyte's chemotactic and infiltration in the bronchoalveolar lavage fluid of inflammatory cell infiltration and allergic asthma.Also can resist trachea and shrink, reduce the cough number of times, reduce the phenol red secretory volume of respiratory tract.(6) polysaccharide components such as alduronic acid that influence in the Radix Glycyrrhizae to function of immune system can improve serum levels, reticuloendothelial system monokaryon function, can induce nitric oxide to produce, and strengthen the ability of con A lymphocytic emiocytosis.Radix Glycyrrhizae is slightly extracted and suppresses the sensitizing antibody generation, control penicillin anaphylaxis shock.(7) antitumor, mutation isoliquiritin unit can suppress the propagation of DU145 and LNCaP prostate gland cancer cell.The Glycyrrhiza glabra L. extract suppresses the mutation of X ray, N-NSC-23909 and wearing out of bone marrow cell chromosome.(8) detoxifcation, influence the drug metabolism Radix Glycyrrhizae and can reduce Semen Strychni toxicity, but the cardiac toxicity that the aconitine in the antagonism Radix Aconiti Lateralis Preparata brings out.Glycyrrhizin can improve the active anticancer of cyclophosphamide and vincristine, reduces the cyclophosphamide toxic and side effects.(9) infringement has protective effect to the middle cerebral artery Focal Cerebral Ischemia Reperfusion to the flavones ingredient such as Radix Glycyrrhizae aglycon that influences of brain, renal function; Glycyrrhizic acid can improve brain mitochondria ATP enzyme, cerebral tissue lactic acid dehydrogenase activity, alleviates cerebral edema; Alleviate the injury of kidney that folder closes the acute ischemia re-perfusion model that the bilateral kidney base of a fruit causes.(10) the deferential contraction that effect antagonism norepinephrine, acetylcholine, the histamine of reproductive system caused suppresses uterine contraction; The dysmenorrhea that oxytocin etc. is brought out has analgesic activity.Glycyrrhizic acid can promote the salpingitic immunologic function of phenol.(11) the antioxidation Glycyrrhiza glabra L. calmly and Spain's Glycyrrhiza glabra L. is fixed has protective effect to the liver mitochondrion peroxide injury, can suppress hydrogen peroxide haemolysis.(12) other interaction energies reduce diabetes erythrocyte sorbitol, increase the tyrosinase activity and the melanin content of melanoma cells, improve the internal ear auditory function; Enoxolone suppresses the propagation of lymphocyte and macrophage, prolongs the time-to-live that graft is touched at the angle; Carbon tetrachloride liver fibrosis due bone loss is prevented effect.
Flos Chrysanthemi: (1) is antibiotic, antivirus action Flos Chrysanthemi decocting liquid has inhibitory action to staphylococcus aureus, beta hemolytic streptococcus; The Flos Chrysanthemi infusion to trichophyton, Trichophyton concentricunm, permitted blue achorion, Du's big belly microspore tinea bacterium difficult to understand, rust microspore's tinea bacterium, Pilus Caprae seu Ovis sample microspore tinea bacterium, epidermophyton inguinale, epidermophyton rubrum, star-shaped nocardia inhibitory action arranged; Flos Chrysanthemi has in various degree inhibitory action to herpes simplex virus (HSV-1), poliovirus and Measles virus; Flos Chrysanthemi also has the anti-AIDS effect, be the new active component of anti-HZV from wherein separating the acacetin-7-O-B-D-O galactopyranoside that obtains, and toxicity is quite low.(2) to the effect of arteria coronaria.The Flos Chrysanthemi preparation has the effect that increases heart coronary flow, makes by the ischemia that stimulates mesencephalic centre to cause to improve, and improves the anoxybiotic toleration that reduces pressure.The phenol part of Flos Chrysanthemi preparation can increase the heart coronary flow; To myocardial infarction, coronary atherosclerosis or blood supply insufficiency, energy blood flow increasing and nutrient flow amount are strengthened the effect of myocardial contraction and increase oxygen consumption.(3) to the influence of cholesterol metabolism.The Flos Chrysanthemi water decoction can suppress the vigor of the 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the hepatomicrosome, activates cholesterol hydroxylase, thereby plays the effect of quickening cholesterol metabolism.Flos Chrysanthemi extract is to the rising effect of having clear improvement of serum cholesterol; can keep serum total cholesterol constant substantially; and improve the HDL concentration that protective effect is arranged, and reduce the LDL concentration that damaging effect is arranged, under the high lipid diet situation, have the effect that suppresses cholesterolemia and triacylglycerol rising.(4) function in delaying senility.Flos Chrysanthemi is life-saving obviously, and the glutathion peroxidating is reduced, and improves heart hypoxia-bearing capability, prolongs life span.Flos Chrysanthemi is removed the ability of oxygen-derived free radicals in addition.Flos Chrysanthemi extract damaged and can enter cell membrane to biomembranous ultra-oxygen anion free radical glyceride shields.(5) antitumor action.The Herba Taraxaci match big gun type 3-hydroxyl triterpenes of separating in the Flos Chrysanthemi is to being suppressed the skin tumour diffusion by 12-O-myristoyl phorbol-13-ester (TPA).(6) other effects.Flos Chrysanthemi extract is to there being obvious inhibitory action with Cytochrome P450, and has certain subtribe selectivity.
Semen Ricini: the nonirritant of (1) discharge function Semen Ricini own, the part is used for skin can make emollient, but back for oral administration can be generated castor oil acid and glycerol by the pancreatic lipase hydrolysis in small intestinal, the former is a kind of unsaturated hydroxy aliphatic enzyme, the same with other anion surfactants, can reduce small intestinal to electrolyte and moisture absorption, accelerate the intestinal content transporting velocity, can produce discharge function to the 4ml that is grown up on an empty stomach, but conventional amount used is 15-60ml, and the back 2-6h that takes medicine can discharge 1-2 a large amount of semi-solid bakings just.Because Oleum Ricini acts on small intestinal, can influence nutraceutical absorption, general only exemplary application just when needs are sought a quarrel full intestinal emptying, as when carrying out intestinal inspection.(2) antitumor action is given birth to Semen Ricini and is irritated stomach, and people's pulmonary carcinoma transplanted tumor is had obvious inhibitory action.(3) do the cell surface molecule CD4 (RCD4) of HIV (human immunodeficiency virus) effect reorganization and the conjugate of the active subunit of R, the H9 cell that acquired immune deficiency syndrome (AIDS) (HIV) is infected has the specific killing effect, and the lethality of the H9 cell of infected by HIV is not had only the former 1/1000, this species specificity lethal effect can be blocked by RGP120, RCD4.The A chain of the R of desaccharide and the conjugate 2 * 10-9MOL/L of the mankind to the monoclonal antibody of HIV Protein G P41 and P24 are at external human T-cell's tool cytotoxicity to infected by HIV.(4) immunoreation (5) can cause blood pressure drops, respiration inhibition to the effect ricidine. of cardiovascular and respiratory system is oral.(6) other effects gavage antipyretic remarkable antipyretic effect.(7) physiological disposition R is difficult in vivo by various enzyme hydrolysiss, so keep more of a specified duration, then very fast discharge after the hydrolysis, all keep higher concentration in 5 hours inherent each tissues and the organ, be up to spleen, be followed successively by kidney, the heart, liver and thymus, descend rapidly then, disappeared in the liver through 10-12 hour, other organ-tissues disappeared through 10-30 hour.Mainly discharged by urine, row's remittance amount was on 5-7 hour peak.
Radix Trichosanthis: (1) causes miscarriage and the antiearly pregnancy effect causes the miscarriage effect, and strengthens the spontaneous activity in its uterus on the throne, also can improve gravid uterus prostaglandin content, and blastocyst is had damaging action; Uterus and chronic uterus fistula are shunk to be strengthened.(2) antitumaous effect trichosanthin (trichosanthin) has highly single-minded affinity to trophoblastic cell and choriocarcinoma cell, has special cytotoxicity, and obviously prolonged life cycle.The ability that lotus tumor erythrocyte sticks immune complex be can strengthen, ehrlich ascites cell growth, lung cancer cell line, colorectal cancer cells strain, osteosarcoma cell line and human amniotic cell strain growth suppressed.(3) the immune trichosanthin (trichosanthin) that influences is had immunostimulation and two kinds of effects of immunosuppressant, can strengthen humoral immune function, immunosuppressive action is arranged.(4) anti AIDS virus trichosanthin (trichosanthin) can suppress HIV (human immunodeficiency virus) (Human Immunodeficiency Virus) (HW) duplicating in the immunocyte that infects, and reduces the viable count that is infected by the virus in the immunocyte.Trichosanthin (trichosanthin) has nuclease, and DNA is made the Double helix relexation.
Bull frog gallbladder: contain chenodeoxy cholic acid, lithocholic acid etc.Stronger inhibition is arranged and kill the effect of various bacteria virus, the cell cultured supernatant secretion of bile, wherein the moisture more than 90% can make stiff material in liver progressively dilute, artery and vein, portal vein and bile duct are diluted and increase along with stiff material, intrinsic pressurely increase gradually, sphincter dilatation, and make various obturators discharges in the liver.
Radix Scutellariae: (1) anti-microbial effect has inhibitory action to staphylococcus, Streptococcus hemolyticus, diphtheria liver bacterium, Bacillus typhi and vibrio cholera, streptococcus pneumoniae, dysentery bacterium, escherichia coli, Salmonella paratyphi, anthrax bacillus, nuclear bacillus, Bacillus proteus and Pseudomonas aeruginosa; To will congratulate, this is close, Fu Shi and bacterium sonnei all have and suppress or killing action.Signal and communication path by the blocking-up cell plays a role.Can alleviate pathological lesion and the loss of the metainfective pulmonary of influenza virus PR8 strain that the staphylococcus aureus extracellular toxin brings out.Can significantly suppress duplicating of HIV1 in the peripheral blood lymphocytes that phytohaemagglutinin causes, to then showing significant cytotoxicity at the cem cell of carrying HIV.(2) Immune Effects is had dual regulation to peritoneal macrophage, low dosage can significantly increase macrophage phagocytic dimethyl diaminophenazine chloride and lysozyme content, and high dose then plays inhibitory action.Lipopolysaccharide-induced lymphproliferation response is had dose-effect relationship, when low dosage, all show as the promotion lymphopoiesis, then show as the obvious suppression effect during high dose.Differentiation may have certain regulating action to lymphocyte, erythrocyte immune is sticked function have facilitation.The cellular immune function that can obviously improve ischemic heart failure is unusual, and the immunoregulation effect of baicalin is the depleted at heart weight mechanism of protection ischemic.(3) bring high blood pressure down and diuresis can make chronic renal hyperpietic blood pressure drops, heart rate is slack-off.(4) effect for reducing blood fat can reduce T-CHOL in the liver, free cholesterol and triacylglycerol, can increase the serum high-density LP cholesterol.Can suppress norepinephrine fatty tissue is promoted fat-splitting effect.(5) mechanism of the lipid peroxidation that causes with antioxidant radical in the protective effect baicalin of ischemical reperfusion injury there is protective effect to the cardiac muscle of reperfusion injury.Protection to the diabetes cerebral ischemia reperfusion injury; can dwindle the cerebral infarction volume of diabetes cerebral ischemia reperfusion injury; alleviate the leukocyte infiltration degree; the expression of the activity of myeloperoxidase of ischemic region and iuntercellular adhesion molecule 1 (ICAM1) mRNA all significantly reduces, and its protective effect may to reduce microvascular permeability etc. relevant with the expression that suppresses ICAM1.Can obviously reduce by high-calcium ionic concentration level in the inductive neuroglial cytoma of norepinephrine, it falls calcium mechanism may be relevant with the activity that reduces cell membrane phospholipid enzyme C.(6) antiplatelet aggregation and blood coagulation resisting function can suppress Fibrinogen by thrombin induction to fibrinous transformation.To the disseminated inravascular coagulation of endotoxin induced, can prevent platelet and fibrinogenic minimizing.(7) antioxidation has the reduction effect to aspartate aminotransferase and the alanine aminotransferase that the oxidation vegetable oil raises.Can obviously reduce by the inductive liver mitochondrion lipid peroxidation product of N-nitrosodimethylamine mda content.(8) antitumaous effect has cytotoxic reaction to leukemia L1210 cell, and the proliferation in vivo of LA795 tumor strain is had significant inhibitory effect.Can regulate a year cell cycle, the propagation that suppresses tumor cell shows as the inhibition growth of tumor.The effect clearing away heat-fire, hot-tempered wet detoxifcation, hemostasis, antiabortive, cure mainly the cough due to lung-heat, the calentura unconsciousness due to high fever, the liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat is let out dysentery, and pyretic stranguria is told nosebleed, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle.
Pericarpium Citri Reticulatae: (1) has gentle stimulation to the effect of digestive system to gastrointestinal tract, but pneumatosis in the intestinal tube is got rid of in the secretion of facilitating digestion liquid, and effect duodenum and antagonism intestinal shrink.(2) the effect Pericarpium Citri Reticulatae water solublity total alkaloids to cardiovascular system can increase cardiac output and shrinkage amplitude, increase the pulse pressure difference and the heart eliminating amount of whenever fighting, improve cardiac index, SI, stroke work index, and increase myocardial oxygen consumption and peripheral vascular resistance that can be of short duration, the rising blood pressure; And the arteriosclerosis that high fat diet causes there is certain preventive effect.(3) to the effect of respiratory system 1. the contained volatile oil of phlegm-dispelling functions Pericarpium Citri Reticulatae the zest phlegm-dispelling functions is arranged, sputum is easily brought up; 2. antiasthmatic effect has faint dilating effect to bronchus.(4) effect to reproductive system has inhibitory action to the uterus, can make it lax fully during high concentration.(5) to Immune Effects to serum lysozyme content, serum coagulation antibody titre, cardiac blood T lymphocyte E rosette forming rate all has remarkable potentiation, for the T lymhocyte transformation rate inhibitory action is arranged but.(6) antiinflammatory action can suppress the vascular permeability that kistrin, chloroform cause increases.(7) antioxidation can be removed oxygen-derived free radicals and hydroxy radical, the tool antioxidation.(8) other effects can be shortened hemorrhage and clotting time.
Fructus Amomi: (1) antiplatelet aggregative activity has the obvious suppression effect to the inductive platelet aggregation of A1P, and can make corresponding prolongation action time; The acute death that arachidonic acid or collagen and epinephrine mixture are brought out has obvious protective effect, and expansible blood vessel or inhibition blood alkane are synthetic.(2) effect to digestive system fetters the Gastric Mucosal Cells obstacle that acute gastric mucosa damages, indomethacin-ethanol causes that hydrochloric acid causes, water seaoning stress ulcer, pepsin activity have obvious inhibitory action, can significantly reduce gastric acid secretion; Obvious persistent choleretic effect is arranged, facilitation is arranged, also can promote the gastrointestinal transportation function removing indigestion treatment distension and fullness in the abdomen and intestinal movement.(3) other effects have obvious analgesic activity, and can significantly reduce the antibody cell number.
Cortex Magnoliae Officinalis: (1) myorelaxant effects Cortex Magnoliae Officinalis alkaloid has relexation to striped muscle, and magnolol and honokiol abdominal cavity have the central myorelaxant effects and obviously suppress extensor reflex.The effect of the excited normal gastrointestinal motility of energy, and the obvious inhibition that improves gastrointestinal motility when suffering a shock.(2) the antiulcer action magnolol is to pylorus ligation, and the gastric ulcer due to water logging stress ulcer and the mercaptoethylmaine all has the inhibition effect.(3) resisting pathogenic microbes effect magnolol and honokiol all have antibacterial action to staphylococcus, Hemolytic streptococcus, diphtheria corynebacterium, anthrax bacillus, escherichia coli, Bacillus proteus, dysentery bacterium, Bacillus typhi, Salmonella paratyphi, trichophyton, rust trichophyton, acrothesium floccosum, microspore's tinea bacterium, Trichophyton concentricunm, trichophyton, trichophyton, gram positive bacteria, acid fast bacteria and fungus etc.(4) anti-inflammatory and analgesic effect has obvious analgesic activity, can reduce the abdominal cavity capillary permeability that acetic acid causes and raise, and obviously suppress the ear foot swollen and that carrageenin causes that dimethylbenzene causes and open up swelling.(5) antitumor action magnolol and honokiol and monoterpene base magnolol are the inhibitor of antigen (EBV-EA) activation, and the promotion to skin tumour that the second stage of carcinogenic test in the body is caused has the obvious suppression effect.(6) anticoagulation magnolol and honokiol can suppress the gathering and the ATP release of the platelet rich plasma of collagen and arachidonic acid-induction, and ADP, platelet activating factor (PAF) or thrombin induction person are not then had effect.The TXB2 that whole blood, platelet aggregation, platelet blood plasma, arachidonic acid or the thrombin of washing caused generate and cell that arachidonic acid or collagen are caused in Ca2+ raise inhibitory action arranged.(7) other effect magnolol and honokiol have stimulation to cyclic nucleotide phosphodiesterase, and the effect of falling serum alanine aminotransferase (ALT) and falling blood ammonia is arranged; Can obviously prevent hepatic fibrosis and cirrhotic formation, improve cell immune function of human body; Have the blood plasma superoxide dismutase (SOD) of raising activity, reduce the biological effect of lipid peroxide (LPO) content; And have the inflammation of reduction district capillary wall permeability, suppress the effect of leukoplania and inhibition proliferation of fibrous tissue.The magnolol oral absorption is rapid, and 15min blood drug level reaches peak value, and 8h is peak value once again, and magnolol and metabolite thereof have the liver sausage circulation, mainly are distributed in gastrointestinal tract and liver, and inferior is kidney, pancreas and lung.The main metabolites of discharging from bile is [ring-14C], magnolol-2-O-glucuronate.
Herba Hedyotidis Diffusae: (1) can strengthen the ability of leukocytes phagocytic Staphylococcus albus in the peritoneal fluid and the blood middle leukocytes phagocytic function to staphylococcus aureus to Immune Effects.Can significantly reduce the hypertrophy number of bow structure in the initial immunity patient splenocyte.Can obviously strengthen canavaline and bacteria lipopolysaccharide to the splenocyte breeder reaction; Strengthen the killing ability of delayed hypersensitivity and cytotoxic T lymphocyte simultaneously, reduce thymic weight.(2) antitumor action can suppress the growth of solid tumor, can improve the damage of the atrophy of immune organ and the hemopoietic system of caused by cyclophosphamide; Strengthen killer cell to the specific killing of tumor cell active and mononuclear cell to the phagocytic function of tumor cell.Can promote the release of storage calcium in the cell and the interior stream of the outer calcium ion of born of the same parents, significantly improve the concentration of free calcium in the cervical cancer cell.(3) irritate stomach for gastric mucosa damage due to the indomethacin to the protective effect Herba Hedyotidis Diffusae of gastric mucosa damage and improve the serum of gastric ulcer due to the indometacin and the SOD vigor of gastric tissue, reduce MDA content, point out its mechanism of action also relevant with antioxidation.(4) the antioxidation Herba Hedyotidis Diffusae polysaccharide has tangible scavenging action to negative oxygen-derived free radicals.
Flos Lonicerae: (1) resisting pathogenic microbes effect all has certain inhibitory action to multiple Grain-positive such as staphylococcus aureus, Staphylococcus albus, Hemolytic streptococcus, pneumobacillus, meningococcus, Bacillus typhi, Salmonella paratyphi, escherichia coli, dysentery bacterium, Bacillus proteus, bordetella pertussis, Pseudomonas aeruginosa, tubercule bacillus, mycobacterium hominis, leptospira, vibrio cholera and negative bacterium, also can show to land to alleviate lung lesion.(2) the Lonicera fulvotnetosa Hsu et S. C. Cheng. Ms total saponins in the antitoxic action Flos Lonicerae has therapeutical effect to the patient of Pseudomonas aeruginosa endotoxicosis, can improve its caused leukopenia and body temperature and reduce, and obviously alleviate the pathological lesion of liver.(3) to suppress due to carrageenin, the Ovum Gallus domesticus album be that the inflammatory exudation and the granulation tissue of swelling granulation cyst forms to antiinflammatory action.(4) immune interaction energy is promoted the phagocytic function of leukocyte, inflammatory cell; Can reduce T cell a-naphthyl acetate esterase positive percentage, the pair cell immunity has inhibitory action.(5) effect for reducing blood fat can reduce the enteral cholesterol absorption, reduces content of cholesterol in the blood plasma.(6) the central excitation effect can cause central nervous system's excitement.(7) other effects of antiearly pregnancy effect (8) have tangible cytotoxicity to sarcoma and ehrlich carcinoma.
Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae): (1) resisting pathogenic microbes effect to staphylococcus aureus, escherichia coli, Pseudomonas aeruginosa, Fei Shi dysentery bacterium, paratyphoid fever type bacillus, read the strain coccus in vain, cattle type Brucella has certain inhibitory action.The effect of anti-herpes simplex virus is arranged.(2) anti-endotoxin effect can make endotoxic active the reduction.(3) the antitumor action antagonist relies on macrophage intermediary tumor cell destruction effect activation.The mechanism of action that is similar to anticancer polysaccharide makes its energy antitumor.(4) the anti-gastric-ulcer effect has inhibitory action to gastric acid secretion, and stress ulcer is had significant protective effect, can obviously alleviate the gastric mucosa infringement, and ulcer incidence rate and ulcer index are obviously descended.(5) function of gallbladder promoting and the effect that protects the liver effect that hepatic injury due to the carbon tetrachloride is all had remarkable reduction serum alanine aminotransferase and alleviates hepatic cell fattydegeneration.(6) immunoregulation effect has the effect that improves and improve cellular immunization and non-specific immunity, and infringement has tangible recovery and protective effect to immunologic function.(7) antioxidation can effectively be removed ultra-oxygen anion free radical, hydroxy radical, suppresses the oxidation of unsaturated fatty acid.Its extract can reduce melanic generation and pigmentation.
Herba Taraxaci: the public tribute of (1) resisting pathogenic microbes effect Pu has certain inhibitory action to staphylococcus aureus, escherichia coli, Pseudomonas aeruginosa, bacterium flexneri, paratyphoid fever type bacillus, Candida albicans, cattle type Brucella.The test of 100% Herba Taraxaci decoct paper disk method has inhibitory action to Bacillus typhi, and the Bacillus tuberculosis is had inhibitory action.Herba Taraxaci water logging agent to trichophyton, Trichophyton concentricunm, permitted blue achorion, Du's big belly microspore tinea bacterium difficult to understand, rust microspore's tinea castor, Pilus Caprae seu Ovis sample microspore tinea bacterium, Gypsum Fibrosum sample microspore tinea bacterium, epidermophyton inguinale, epidermophyton rubrum, star-shaped nocardia etc. inhibitory or killing effect all arranged.(2) add endotoxin in the anti-endotoxin effect Herba Taraxaci extract, the activity that records toxin after the interaction reduces, its attenuation multiple is 9.3[9]. (3) antitumor action antagonist relies on macrophage intermediary tumor cell destruction effect activation, and the Anticancer Effect and Mechanism of Herba Taraxaci is the mechanism of action that is similar to anticancer polysaccharide such as lentinan.Radix Taraxaci has the anticancer effect that has.(4) the heavy decocting lumbar injection of anti-gastric-ulcer effect Herba Taraxaci pure wine has resistance usefulness to gastric acid secretion, and the inductive gastric acid secretion effect of obvious resistance histamine, pentagastrin and carbachol is arranged.Stress ulcer, pylorus ligation gastric ulcer and dehydrated alcohol damage gastric mucosa all there are significant protective effect, can obviously alleviate the gastric mucosa infringement, ulcer incidence rate and ulcer index are obviously descended.(5) function of gallbladder promoting and the hepatoprotective effect effect that all has remarkable reduction serum alanine amino to move enzyme and alleviate hepatic cell fattydegeneration to hepatic injury due to the carbon tetrachloride.(6) the immunoregulation effect Herba Taraxaci has the effect that improves and send cellular immunization and non-specific immunity, and the immunologic function infringement that cyclophosphamide caused is had tangible recovery and protective effect.(7) antioxidant radical effect Herba Taraxaci is carried and is received the effect that the thing total flavones has quasi-SOD, and the effect of the cruel amino acid enzymatic activity of stronger inhibition is arranged.
Fructus Forsythiae: Fructus Forsythiae fat glycosides (forsythoside) and phillyrin (forsythin in (1) anti-microbial effect Fructus Forsythiae, phillyrin) many kinds of antibacterials there is inhibitory action, its most responsive antibacterial is had: staphylococcus aureus, Hemolytic streptococcus, micrococcus catarrhalis, Pseudomonas aeruginosa, hog cholera bacillus, anthrax bacillus, diphtheria corynebacterium; The antibacterial of medium sensitivity has viridans streptococci, pneumobacillus, escherichia coli, bacillus enteritidis, Bacillus typhi, paratyphoid bacillus A, Bacillus paratyphosus B, shigella flexneri, bacterium sonnei, mentally disturbed he dysentery bacterium, Si Mizi dysentery bacterium, vibrio cholera, bacillus pestis, Bacillus tuberculosis; Antibacterial than low sensitivity has proteus vulgaris.The antimicrobial main component of Fructus Forsythiae is Fructus Forsythiae fat glycosides and forsythol (being phillyrin).Its contained phenylpropyl alcohol glycoside has very strong antibacterial activity, and Fructus Forsythiae seed volatile oil has shown tangible anti-influenza virus activity, and in addition, Fructus Forsythiae also has certain inhibitory action to trichomonas vaginitis.Many kinds of antibacterials there is inhibitory action, anti-influenza virus activity is arranged, influenza infection is had significant protective effect.Trichomonas vaginitis also there is certain inhibitory action.(2) it is unreal that the phenylpropyl alcohol glycosides of the effect Fructus Forsythiae of inhibition lipoxygenase activity, phosphodiesterase activity has the active effect of the lipoxygenase of inhibition D.Lignanoids has the effect that suppresses phosphodiesterase activity, and the aglycon part is stronger than the effect of glycosides.(3) tell the effect Fructus Forsythiae and can suppress emetic action in the town, reduces the vomiting number of times, but do not change the incubation period of vomiting, and it may be to suppress the chemoreceptor trigger zone of medulla oblongata that action principle is told in its town.(4) anti-liver injury effect Fructus Forsythiae obviously alleviates liver degeneration and downright bad effect to cause hepatic injury to have with carbon tetrachloride, make most of hepatic glycogen and rna content recovery or approaching normal, serum alanine aminotransferase is active significantly to be reduced, and this shows that it has the anti-liver injury effect.(5) oleanolic acid (oleanolic acid) and ursolic acid have the effect that reduces diabetes model and glucose in urine in other effect Fructus Forsythiaes.The intravenous injection of Fructus Forsythiae aqueous extract has obvious hypotensive effect to spontaneous hypertension, and (forsythin phillyrin) also has hypotensive effect with Fructus Forsythiae aglycon (phillygenin) to phillyrin.
Semen Persicae: (1) obviously increases the blood flow of femoral artery and reduces vascular resistance and the flow of perfusate the interaction energy of blood circulation, and can eliminate the blood vessel function that contracts of norepinephrine, and the liver surface microcirculation is had some improvement.(2) blood coagulation resisting function and antithrombotic form Semen Persicae composition triolein (triolein) and can make bleeding time and the equal significant prolongation of clotting time, also can suppress its blood clot retraction fully.(3) antiinflammatory action has stronger anti-carrageenin pedal swelling, and granuloma, inflammatory cell and fibroblast are had inhibitory action.(4) other effect has the uterine contraction effect, helps the involution of uterus and hemostasis in puerperal; Remarkable analgesic activity is arranged, suppress writhing response.
Rhizoma Chuanxiong: (1) 1. can make the myocardial contraction rate strengthen to action of the heart to the influence of cardio-cerebrovascular, and can accelerate heart rate; Stream in the myocardial cell there is significant inhibitory effect, reduces the ischemic myocardium protein expression and reduce the ischemic myocardial cells apoptosis.2. the effect to blood vessel and blood pressure can suppress to flow in hypoxic pulmonary vascular contractile response right ventricular hypertrophy and the vascular smooth muscle, and Hypoxic Pulmonary Hypertension in Rats is had therapeutical effect.But 3. to the influence coronary blood flow increasing of coronary flow, increase body endogenous superoxide dismutase activity, reduce the malonaldehyde level, hemorrhagic shock is had preventive and therapeutic effect, and ischemic myocardial cells nuclear calcium transport function reduction is had antagonism.4. to the expansible cerebrovascular of the effect of myocardial ischemia and perfusion injury, reduce vascular resistance, showing the cerebral blood flow increasing amount, can obviously suppress blood plasma thrombosis globulin behind the ischemia, the rising of platelet factor and thromboxane has protective effect to cerebral ischemia.5. the influence to cerebral circulation can increase mesentery blood flow and the open number of blood capillary, can improve chronic bulbar conjunctiva and pia mater encephali microcirculation disturbance.6. to microcirculatory influence.(2) influence of blood system there is remarkable inhibitory action to the platelet aggregation of generation, collagen and the thrombin induction of platelet malonaldehyde, and makes the rapid depolymerization of accumulative platelet.(3) but to the effect renal blood flow increasing of urinary system, and remarkable diuresis is arranged; Nephritis and original position nephritis all there are certain preventive and therapeutic effect, also Rhizoma Chuanxiong or ligustrazine are also had good protective action.(4) can strengthen the phagocytic function of mononuclear phagocyte to immune influence, improve the positive percentage that lymhocyte transformation rate and acid naphthyl acetate esterase detect, also can promote the formation of erythrocyte antibody (EA).(5) antitumor and anti-radiation function can reduce the surface of tumor cells activity, change cancer patient's high blood coagulation state, and anticancer shifts, and improve the sensitivity of tumor to radiation, alleviate radiation injury.(6) other effects can reduce progesterone content content in interior prostaglandin of ovary and the blood, improve uterus progesterone receptor specific bond amount, also can prevent and treat the plain nephrotoxicity of the big enzyme of celebrating, improve the effect that acute critical pancreatitis merges injury of lung, also can promote the chondrocyte secretion anabolism factor, stimulate cellular proliferation and protein synthesis.Mainly be distributed in the abundant organ of blood flows such as liver, the heart, spleen, brain and be easy to enter the central nervous system through blood brain barrier, spleen, blood, the muscle medicine is eliminated fast.
Rhizoma Curcumae: (1) antitumor action has obvious inhibition and destruction to the growth of multiple tumor strains such as ehrlich ascites cell, leukemia and ascites hepatoma cells.(2) monoterpenes in the antiearly pregnancy effect Rhizoma Curcumae and sesquiterpenoids antiearly pregnancy effect that highly significant is arranged also has certain anti-implantation effect.(3) limonene volatile oil components such as (limonene) can suppress the growths of staphylococcus aureus, B-Hemolytic streptococcus, escherichia coli, Bacillus typhi, vibrio cholera etc. in the antibacterial action Rhizoma Curcumae.(4) hepatoprotective effect has tangible reduction effect to the alanine aminotransferase rising that carbon tetrachloride, thioacetamide cause.(5) to the interaction energy of acute renal failure the acute renal failure symptom obviously being seen alleviates.(6) the inhibition platelet is poly-has significant inhibitory effect with antithrombotic formation to platelet aggregation and thrombosis, and can obviously reduce blood viscosity, shortens erythrocytic electrophoresis time.(7) limonene volatile oil component Dichlorodiphenyl Acetates such as (limonene) causes the inhibitory action that peritonitis and ear's inflammation and granuloma induced by implantation of cotton pellets have highly significant in the antiinflammatory action Rhizoma Curcumae.
Radix Achyranthis Bidentatae: the writhing response of (1) analgesic activity Dichlorodiphenyl Acetate has significant inhibitory effect, and the different processed product of Radix Achyranthis Bidentatae all has analgesic activity to a certain degree, and is wherein strong and lasting with wine Radix Achyranthis Bidentatae (processed) analgesic activity.Radix achyranthis bidentatae saponin has significant analgesia role, and action intensity and dosage present certain dose-effect relationship.(2) antiinflammatory action can promote the Ovum Gallus domesticus album arthroncus, formaldehyde is arthritic disappears, the human body immunity improving function, activating macrophage to the phagocytic activity of antibacterial and blood vessel dilating, improvement circulation, promote effect such as inflammatory lesion absorption.(3) influence to cardiovascular and breathing has inhibitory action to heart, and contractility is weakened.Obvious vasodilation and of short duration hypotensive effect are arranged, excited with breathing simultaneously in blood pressure drops, accelerated breathing is deepened.(4) antifertility action Radix Achyranthis Bidentatae saponin has significant dose dependent antifertility action, can cause embryo's discharge, death or colporrhagia.(5) influence to hemorheology blood all has remarkable reduction effect to high low shear rate whole blood viscosity, hematocrit, erythrocyte aggregation index; Stasis syndrome is had anticoagulation, prothrombin time and KPTT are prolonged slightly, the blood plasma recalcification time obviously prolongs.(6) the contained ecdysterone of hypoglycemic activity Radix Achyranthis Bidentatae has inhibitory action to the hyperglycemia that alloxan, AIS cause, promotes glucose synthetic protein and the interior glucose glycogen biosynthesis of liver in the liver.(7) to Immune Effects spleen index and thymus index, peritoneal macrophage are increased to erythrocytic phagocytic percentage and phagocytic index.Hematid immunity function there is remarkable facilitation, improves radiation damage serological specificity antibody hemolysin content and increase spleen hemolysis plaque formation cell number, show that it has immunologic function to body fluid.(8) delaying senility function can improve glutathion Peroxidase activity in the blood, reduces the content of lipid peroxide, illustrates to have function in delaying senility.(9) antitumor action Inokopolyose (ABP) has inhibitory action to sarcoma, improves the activity of carcinoma cell, strengthens the cytotoxicity to ehrlich ascites cell.(10) osteoporotic mobility due to other interaction energies increase retinoic acid, losing of the prevention bone mineral nitrogen that retinoic acid caused increases content organic in the bone, improves bone density, thus arrival prevents and treats osteoporotic purpose.
Radix Salviae Miltiorrhizae: (1) 1. can prevent or reduce the generation of the ventricular fibrillation (VF) that is caused by isoproterenol to the influence of the heart, cerebrovascular system to action of the heart, improves survival rate, recovers multiple sinus rhythm, the animals survived time of significant prolongation VF.Sodium tanshinone IIA sulfate has the effect of similar verapamil sample L-type calcium channel blocker simultaneously, and its blocking effect is non-voltage-dependent.2. the effect Radix Salviae Miltiorrhizae Injection to blood vessel and blood pressure can have dilating effect to blood vessel by obvious renal blood flow increasing, and Radix Salviae Miltiorrhizae has hypotensive effect in various degree.3. the influence to coronary flow can make coronary flow obviously increase, and coronary resistance obviously descends, but myocardial oxygen consumption increases to some extent.Danshensu is coronary artery dilator obviously, and coronary flow is significantly increased, and sodium tanshinone IIA sulfate, protocatechualdehyde etc. significantly shrink isolated coronary, and the different monomers chemical compound of prompting Radix Salviae Miltiorrhizae is not the same to effect coronarius.4. the effect salvianolic acid A to myocardial ischemia and myocardial infarction can reduce the incidence rate owing to quiver in the chamber that myocardial ischemia-reperfusion causes; reduce LDH spilling from cell space; reduce MDA content in the ischemic myocardial tissue, thereby damage has the certain protection effect to the proof salvianolic acid A to myocardial ischemia-reperfusion.There is obvious inhibition neutrophil lysosome to discharge to myocardial infarction, engulfs and stick, the effect of control myocardial infarction is arranged.Radix Salviae Miltiorrhizae has calcium channel blocking action to cardiac muscle.5. the influence to cerebral circulation and cerebral ischemia can make infarct size dwindle, and only has mild cerebral ischemic to change individually, illustrates that acute cerebral ischemia has prevention and therapeutical effect.(2) to blood fat and atherosclerotic effect Radix Salviae Miltiorrhizae Injection, in local cerebral ischemia reperfusion stream damage prevention and treatment, no matter treatment group still is the prevention group, infarct size all obviously dwindles, only have mild cerebral ischemic to change individually, demonstrating Radix Salviae Miltiorrhizae has sure prevention and therapeutical effect to acute cerebral ischemia.Danshensu (prgewaquinoneA, B) has the synthetic lipotropism electrophoretic mobility of protein that reaches of the cell of reduction inner cholesterol the effect of slowing down is arranged, MDA content obviously reduces and the toxic reaction of oxidation lipoprotein pair cell obviously weakens, so can be used for atherosclerotic control.In addition, can also raise experimental hypercholesterolemia liver and human fibroblasts ldl receptor mRNA level.(3) anticoagulant and antithrombotic TANSHINONES (tanshinone) I, IIA, IIB, II, III, V, VI, protocatechualdehyde, danshensu (prgewaquinoneA, B), anticoagulation is arranged, can make the external thrombus time lengthening, the thrombosis contraction in length, thrombosis dry weight and weight in wet base alleviate, and platelet adhesion reaction and aggregation capability reduce.(4) resisting oxygen lack TANSHINONES AII sodium sulfonate, danshensu (prgewaquinoneA, the B) life span that can prolong anoxia enduring.(5) to Immune Effects huge carefully roar phagocytic percentage and the phagocytic index bitten obviously improved, spleen antibody generates number and obviously improves, and Radix Salviae Miltiorrhizae is having facilitation aspect the humoral immune function improving.Also can reduce the phagocytic percentage and the phagocytic index of peritoneal macrophage, make the delayed hypersensitivity of lymphocytic conversion ratio decline of T and inhibition normal foot pad.Radix Salviae Miltiorrhizae Injection can prolong the survival period of cardiac muscular tissue, alleviates the blood capillary damage, and protecting myocardial cell alleviates immunocyte and soaks into, and the rejection of energy facedown body fluid and cellular immunization.(6) antiinflammatory anti-allergic effects TANSHINONES (tanshinone) I, II A, II B, II, II, V, VI to vascular permeability increase, acute swollen joint, the reaction of exudative formaldehyde peritoneum and leukoplania and subacute formaldehyde swollen joint have inhibitory action.Can make prostaglandin reduction in the blood, prevent the release of lysosomal enzyme, oxidative metabolism product, alleviate tissue injury, with the development that controls inflammation.(7) to the effect of liver 1. to the liver injury protection effect by reducing synthesizing of TNF-a and postpone and alleviate the irreversibility hepatic injury that causes behind the ischemia, thereby hepatic injury is played a protective role.2. in the facilitation of giving birth to liver regeneration degree, karyokinesis phase index, alpha-fetoprotein recall rate are all increased hepatocyte.Improve the liver blood circulation, increase the pancreas hyperglycemia, improve hepatic glycogen, reduce the liver fat content, promote the generation of RNA, DNA, this is to promoting that liver regeneration has certain effect.3. the anti-hepatic fibrosis carbon tetrachloride causes chronic hepatic injury that the hepatic fibrosis hyperplasia degree is obviously alleviated.Inhibition fibroplasia is arranged, prevent cirrhotic generation.Established fiber is dissipated and absorption.(8) anti-gastric-ulcer effect TANSHINONES (tanshinone) I, IIA, IIB, II, III, V, VI have protective effect to gastric ulcer, and chronic gastric ulcer is also had the healing of promotion effect.Suppress pylorus ligation gastric acid secretion, alleviate the gastric injury that causes by immersion and constraint stress guide.(9) Radix Salviae Miltiorrhizae that influences to sarcoma has cytotoxicity to sarcoma cell.It is synthetic to suppress its DNA.Growth to pulmonary carcinoma, melanoma and sarcoma has inhibitory action, and leukemic life span is obviously prolonged.TANSHINONES has antihepatocarcinoma effect, and salvianolic acid A has the tumor cell of inhibition nucleoside transport activity, and cancerous cell is had lethal effect.(10) 1. can obviously alleviate the order of severity of alveolitis to the influence of respiratory system, reduce lung weight, and can suppress the generation of lipid peroxide, the acute lung injury of preventing bleomycin to cause is arranged the protective effect of injury of lung.2. can obviously suppress pulmonary fibrosis due to the Bleomycin A5 hydrochloride. to the protective effect Radix Salviae Miltiorrhizae of pulmonary fibrosis; lung weight, lung coefficient are obviously reduced; the lung hydroxyproline content obviously reduces, and the pulmonary fibrosis pathological changes obviously is suppressed, and a small amount of inflammatory cell infiltration is only arranged in the lung tissue.(11) improve the renal insufficiency that renal function brings out adenine, all can reduce blood urea nitrogen, creatinine, glomerular filtration rate, renal plasma flow, renal blood flow are significantly increased, and renal function obviously improves, and can significantly increase the discharge of carbamide in the urine, creatinine, sodium and Phos.(12) antioxidation can obviously improve SOD activity in erythrocyte, the heart, liver, the kidney, and lipid peroxide content in remarkable reduction serum, the heart, liver, the kidney is also arranged accordingly.Tanshinone can effectively suppress the cytolipin peroxidating, reduces lipid one DNA addition product and produces.Tanshinone is a kind of new, effective lipid within endothelial cells peroxidating product and the interactional inhibitor of DNA.Salvianolic acid A suppresses cataractous formation by antioxidation.
Cortex Moutan: (1) central inhibitory action can be to convulsion, and is influential to formatio reticularis mesencephali, hypothalamus activation system and cortical reaction path.(2) the cardiovascular system effect is had protective effect to myocardial ischemia due to the coronary ligation, left chamber amount of work is reduced, myocardial oxygen consumption reduces, and coronary flow increases, and blood pressure lowering is arranged and reduce the cardiac output effect.(3) the effect paeonol of blood system is had a significant blood coagulation resisting function external, the mechanism of platelet aggregation is to influence arachidonic acid metabolic, suppresses slow oxygenase, makes that TXA2. is synthetic to be reduced.(4) antiinflammatory action can significantly suppress the constitutional inflammation, secondary inflammation, inductive acute sufficient pawl swelling of carrageenin and auricle edema.(5) can strengthen the phagocytic function of reticuloendothelial system to Immune Effects, make that the carbon time of cleaning up obviously shortens in the body, cell number increases in the peritoneal exudate, can directly promote splenocyte propagation, and can work in coordination with the inductive splenocyte of ConA and breed.Can strengthen peritoneal macrophage and engulf neutrality; Induce macrophage to synthesize nitric oxide.(6) hypoglycemic activity.The hyperglycemia that Portugal's inulin is brought out has the reduction effect.
Radix Asparagi: (1) antibacterial action is to first type and beta hemolysis type streptococcus, diphtheria corynebacterium, and diphtheroid, streptococcus pneumoniae, staphylococcus aureus, Staphylococcus citreus, Staphylococcus albus and bacillus subtilis have inhibitory action in various degree.(2) kill mosquitoes effect (3) delaying senility function can improve old and feeble brain SOD, MDA, Na+, K+-ATP enzyme activity, reduces MDA content; Can significantly improve the enzyme activity of liver plasma membrane Na+, K+-ATP enzyme activity and testis mitochondrion GSH-Px, Na+, K+-ATP, reduce MDA content; The sarcoma of inhibition and the secretion of tumor necrosis factor and the effect of maincenter are arranged.
Radix Ophiopogonis: (1) 1. can improve the cardiac hemodynamics effect to the influence of cardiac function to the effect of cardiovascular system, positive inotropic is arranged and improve the heart pump function; The myocardial contraction that ophiopogonin (ophiopogonin) and total amino acids can strengthen heart strengthens, and coronary flow increases, and heavy dose then suppresses cardiac muscle, reduces coronary flow.2. the interaction energy to myocardial preservation alleviates the myocardial cell anoxia infringement of long-time swimming back, dwindles the effect of infarction size and necrotic zone.3. antiarrhythmic effect ophiopogonin (ophiopogonin) can prevent or resist by chloroform-epinephrine, barium chloride, the inductive arrhythmia of aconitine, and the ventricular arrhythmia incidence rate behind the ligation arteria coronaria 24h is reduced.(2) the resisting oxygen lack Radix Ophiopogonis polysaccharide can improve the hypoxia-bearing capability of subcutaneous injection isoproterenol under the hypobaric hypoxia condition, prolongs the time-to-live of normobaric hypoxia.(3) can increase spleen weight, carbon clearance effect to Immune Effects, stimulate the generation of hemolysin in the serum, the antagonism leukocyte count descends, and strengthens the red cell agglutination rate.(4) the hypoglycemic activity Radix Ophiopogonis polysaccharide can make blood glucose descend, and impels beta Cell of islet to recover the original increase trend of glycogen.(5) removing free radical and delaying senility function stimulates human polymorphonuclear leukocyte's breathing to break out the generation reactive oxygen free radical to carcinogenic promoting agent PMA, and very strong scavenging action is arranged; Can reduce hydroxyproline in the body, suppress monoamine oxidase, MAO (MAO-B) in the brain, and make the active raising of superoxide dismutase (SOD).Superoxide dismutase activity improving, serum Total antioxidant capacity and hematid immunity function reduce the serum mda content, have function in delaying senility.(6) influence to gastrointestinal function can suppress gastrointestinal propulsion, and inhibitory action strengthens with the increase of dosage; Contraction has antagonism to the tetanic property of intestinal smooth muscle.(7) antibacterial action has inhibitory action to Staphylococcus albus, bacillus subtilis, escherichia coli and Bacillus typhi etc.
The bright Radix Rehmanniae: (1) can suppress immunity Flos Rosae Rugosae formation cell in the spleen to Immune Effects, promote activatory splenocyte DNA of con A and proteinic biosynthesis, strengthen interleukin-2 and produce, and can improve the phagocytosis of macrophages of the inductive immunocompromised of acetic acid Ni Songlong.(2) to endocrine influence increase kidney beta receptor maximum binding capacity is returned to normally, can resist the decline of the plasma corticosterone concentration that dexamethasone causes, prevent the adrenal cortex atrophy, but cortex hypofunction on hypophysis-kidney that the part antagonist hormonal causes.(3) other effect antagonism cruor time extendings, the spleen lymphocyte expression of ALP ability of the class yin deficiency syndrome that thyroxine causes is strengthened, accelerate propagation, the differentiation of pluripotential hemopoietic stem cell (CFU-S), bone marrow hemopoietic progenitor cell of red blood cell line (CFU-E).
Radix Scrophulariae: (1) refrigeration function to the heating due to the antityphoid vaccine, has good antipyretic effect to the acid of methoxyl group meat bar.(2) antibacterial action has antibacterial action to staphylococcus aureus, diphtheria corynebacterium, Bacillus typhi, Pseudomonas aeruginosa, group B streptococcus, escherichia coli, shigella flexneri, trichophyton mentagrophytes, Du Yang microspore's tinea bacterium difficult to understand, acrothesium floccosum and ulotrichy microspore tinea bacterium.(3) interaction energy to cardiovascular effect increases coronary flow, myocardium Rb intake; Myocardial ischemia due to the pituitrin there is protective effect, strengthens hypoxia-bearing capability, and certain hypotensive effect is arranged.(4) antiinflammatory, antioxidation can suppress the toe swelling of foot fork dish glue and cobra venom, and external evoked platelet aggregation is had in various degree inhibitory action.(5) hepatoprotective effect suppresses the rising of alanine aminotransferase and aspartate aminotransferase, thus the protection hepatocyte injury; Can improve the survival rate that D-Gal causes the liver primary cultured cell of damage.(6) hypoglycemic activity can cause that blood glucose slightly reduces.
Rhizoma Dioscoreae: (1) hypoglycemic activity Rhizoma Dioscoreae decoct has the effect of prevention and treatment to diabetes.(2) to the effect Rhizoma Dioscoreae of digestive system, fry, parching with earth, when 4 kinds of Rhizoma Dioscoreae processed products of parched with bran decoct causes that at epinephrine the intestinal tube tonicity reduces, can make the pipe intestinal recover the rhythm and pace of moving things, antagonism is obvious; Allantoin contained in the Rhizoma Dioscoreae can be repaired epithelial tissue, promotes skin ulcer face and wound healing, has promoting muscle growth functions, can be used for gastric and duodenal ulcers.(3) can improve its carbon clearance speed to Immune Effects, increase spleen weight and lymphocyte number, Chinese yam polysaccharide can reduce leukocytic effect, improves the lymphocyte transformation function, promote the generation of serum hemolysin, pair cell immunity and humoral immune function have stronger facilitation.(4) the antioxidant activity Chinese yam polysaccharide can reduce the content of microsome lipid peroxide, and hydroxy radical there is scavenging action, can improve red blood cell aging superoxide dismutase activity and hemase vigor, reduce the sugared concentration of concentration, aorta and the heart of lipid concn, cholesterol.(5) other effect life-savings alleviate the infringement that internal organs are subjected to anaerobic environment, improve toleration.
The Radix Astragali: (1) 1. can strengthen the reticuloendothelial system phagocytic function to the effect of humoral immunization to immune influence, increases the serum hemolysin antibody-producing capacity; Astragalus polysaccharides (APS) makes that the T cell number increases in thymus and the spleen, and the spleen antigen binding cell of immunoreation commitment is had facilitation.2. the interaction energy of pair cell immunity significantly improves lunger's cellular immune level, makes T cell phenotype CD3 in the blood, CD4, and CD8 content is increased to normal level.3. to NKT (NK) cell influence Radix Astragali and people's blood lymphocyte, the NK cytoactive is had obvious facilitation, and dose dependent is arranged; The Radix Astragali and people's umbilical blood interferon (P-IFN) 103~104u use in conjunction can make the NK cell improve.(2) influence (1) to organism metabolism can reduce peripheral blood lymphocyte and cerebral tissue beta-2 adrenoceptor by life-saving, can make bacillus bifidus and enterococcus minimizing in the intestinal.(2) flavone in the antioxidation Radix Astragali and saponin constituent all have the effect of good removing oxygen-derived free radicals; (3) metabolism to nucleic acid has facilitation to the hepatocyte RNA that 3H-uridine (3H-UR) mixes, and liver, splenocyte neutral and alkali ribonuclease (RNase) activity are significantly descended.(4) can significantly increase the 3H-leucine to protein and other metabolic effect astragalus polysaccharidess and mix serum and the proteinic speed of liver, promote serum and hepatic protein to upgrade, liver 7a-methylol valeryl CoA-reductase is had obvious inhibitory action.(3) influence to hemopoietic function can make peripheral red blood cells and hemoglobin increase to the hemolytic anemia due to hemorrhagic anemia and the acetylphenylhydrazine, leukocyte republicanism thrombocytopenia to caused by cyclophosphamide has the promotion restitution, can also increase reticulocyte counts and bone marrow nucleated cell number.(4) but to the effect astragaloside coronary blood flow increasing of cardiovascular system, decreased heart rate and reduce the heartbeat amplitude, protective wire plastochondria and " oxygen supply again " myocardial cell can lower the burst size of lactic acid dehydrogenase (LDH), improve the energy metabolism of myocardial cell.(5) but the anti thrombotic action saponin TSA significant prolongation thrombosed time of common carotid artery, and can anticoagulant.(6) antivirus action infects I type parainfluenza virus certain protective role, can improve the Ca secondary injury of infection cell, can suppress duplicating of viral nucleic acid in the infection cell again.(7) but antitumaous effect melanoma, lotus tumor can prolong life cycle.(8) the arthritis effect obviously raises arthritis serum, interleukin and nitrite amount.(9) antiinflammatory and analgesic activity Radix Astragali total glycosides can make neutrophilic leukocyte swim out of the number and the protein seepage discharge significantly reduce, can suppress the increase of vascular permeability.
The Rhizoma Atractylodis Macrocephalae: (1) to the influence of digestive system 1. to the influence of gastrointestinal motility to stomach at the bottom of the flesh bar stronger excitation is arranged, can promote gastrointestinal to arrange into motion.2. the influence to Small Intestine can obviously promote small intestinal pit cell strain cell proliferation and intestinal epithelial cell to divide a word with a hyphen at the end of a line, and can also promote the IEC-6 differentiation.3. the control to gastric ulcer and chronic gastropathy has prevention and therapeutical effect to the pylorus ligation gastric ulcer.4. hepatoprotective effect is significant protective effect to hepatic injury.5. choleretic effect can obviously increase bile secretion.(2) can strengthen antibody to immune influence and produce ability, the phagocytic function of lymhocyte transformation rate and M can promote the secretion of proliferation of bone marrow cells reaction and IL-1 and IL-2, improves peripheral blood WBC quantity, increase spleen and thymic weight, the T lymphocyte function is also had potentiation; Can improve the activity of macrophage, enhancing body non-specific immunity, the growth of anticancer.(3) to the expansible blood vessel of the influence of cardiac muscle and cardiovascular system, heart is inhibitory action, makes blood pressure drops; Isolated atria flesh is had negativity muscular strength and negative chronotropic action, can obviously reduce the contractility of isolated right atrium flesh, its heart rate simultaneously slows down; The positivity ladder-effect of the left atrium flesh that exsomatizes is reduced.(4) antioxidation, old and feeble interaction energy effectively reduce LPO content, can improve erythrocyte sod and GSH-PX activity, suppress the activity of brain monoamine oxidase-B, reduce MDA content in the erythrocyte, to anti-erythrocyte autoxidation haemolysis, and have the effect of the reactive oxygen free radical of removing.(5) antitumor action has inhibitory action to sarcoma, ehrlich carcinoma and lymphosarcoma ascitic type, can strengthen the specificity active immunity of the antigenicity antibody of cancerous cell; Raising body antitumor respond reaches the cytotoxicity to oncocyte.(6) blood sugar lowering can reduce the alloxan diabetes blood sugar level, can reduce the amount of drinking water and the consumption appetite of diabetics, and damage has certain restitution to islets of langerhans, suppresses thymus, the islets of langerhans atrophy.(7) diuresis and anti-ascites interaction energy produce obvious and persistent diuresis, the average light and open density in peritoneum hole is being shown increase, and the peritoneum hole is had stronger regulating and controlling effect.(8) there are calmness, blood coagulation resisting function that the spontaneity contraction and the irritability contraction of unpregnancy isolated uterine are all being manifested inhibitory action.
Rhizoma Polygonati: (1) resisting pathogenic microbes effect can suppress Bacillus typhi, staphylococcus aureus, acid fast bacteria, trichophyton gypseum, Ke Shi type epidermophyton, trichophyton, Shen gram Capreolus capreolus (Linnaeus) silk bacterium, Cryptococcus histolyticus, read strain bacterium, staphylococcus aureus, Pseudomonas aeruginosa in vain has and suppresses to do.(2) interaction energy to cardiovascular system extremely significantly increases coronary flow, and the activity of lung angiotensin converting enzyme is had inhibitory action.(3) the effect for reducing blood fat polygonatum polysaccharide can significantly reduce serum-concentration, reduces the formation that the aortic tunica intima foam is carefully used born of the same parents.(4) delaying senility function can make prolong life cycle, improves the SOD activity in the liver; Reduce the whole blood lipid peroxide and generate, strengthen whole blood glutathion Peroxidase activity, reduce the serum creatine kinase level.(5) influence to Immune Effects and cyclic nucleotide content has facilitation to acid a-naphthyl acetate esterase positive lymphocyte percentage rate, can significantly reduce normal plasma cAMP, cGMP content.(6) influence to blood glucose can suppress the blood glucose value that epinephrine brings out hyperglycemia strongly.(7) the effect polygonatum polysaccharide that improves the learning and memory reproduction can improve learning and memory and memory represents ability, reduces errors number.(8) latent time in the test of labyrinth is obviously shortened in other effects, and its hypoxia-bearing capability is obviously improved, can the significant prolongation swimming time.
Radix Codonopsis: (1) enhancing body stress ability Radix Codonopsis polysaccharide can improve heat-resisting ability, strengthens normal reaching and extracts adrenal and anoxia ability that cause, and reduce Vitamin C content in the adrenal gland.(2) enhancing human body immunity ability Radix Codonopsis injection can make the quantity of peritoneal macrophage increase, and cell volume increases, and pseudopodium increases, and phagocytic power is strengthened; In the cell in DNA, RNA, the sugar, acidic acid enzyme, ATP enzyme, acid naphthols esterase, succinic dehydrogenase activity all obviously strengthen.Pollen polysaccharide can make in the sugar in the peritoneal macrophage, acid phosphatase and acetic acid naphthol ester enzymatic activity strengthen, can obviously strengthen lymphocyte transformation, antibody forming cell's function, improve the coagulation antibody titre, the regulating action and the body's immunological function state of prompting Radix Codonopsis pair cell, humoral immunization are closely related.Radix Codonopsis polysaccharide has facilitation to the ability of splenocyte secretory antibody, and serum antibody level and splenocyte secretory antibody ability are restored.(3) superoxide dismutase activity of human blood can improve in delaying senility function Radix Codonopsis extract, increases the ability of removing free radical, and the prompting Radix Codonopsis has certain function in delaying senility.(4) stomach is irritated by antiulcer action Radix Codonopsis extract, and the gastric mucosa damage that dehydrated alcohol, strong acid and highly basic are caused all has significant protective effect.,, have significant protective effect or promote the ulcer healing effect irritability, pyloric ligation ulcers, the U.S. hot type of suction diindyl, aspirin type and chronic acid type gastric ulcer.(5) central nervous system is acted on Radix Codonopsis decocting alcohol extract lumbar injection, peaceful, convulsions incubation period and death time that pentylenetetrazole brings out on can significant prolongation, and anti-electrofit effect is arranged.(6) to blood and hemopoietic function influence the Radix Codonopsis injection, can suppress external thrombus and form, reduce hematocrit, reduce erythrocyte electrophoresis value and blood viscosity.(7) can improve heart pump blood volume and not influence heart rate cardiovascular effect Radix Codonopsis extracting solution, increase brain, lower limb and SBF, this extract is dropped on the mesentery, can expand blood capillary and blood flow is increased, and can be to adrenolytic effect.(8) do the release of inducing that tumor assosting effect Radix Codonopsis decoct can suppress prophage, escherichia coli reactions is had stronger inhibitory action, anti-fall out effect is arranged, can also suppress the gene mutation of the yeast cells that hydroxyurea brings out.(9) the Radix Codonopsis injection that influences to blood glucose has antagonism to the hypoglycemia that insulin causes.
Burnt short, bristly hair or beard: contained lipase can promote fat digestion in the burnt short, bristly hair or beard of (1) facilitating digestion effect, and can increase the secretion of peptic digestion enzyme, facilitating digestion.Gastrointestinal function is had certain regulating action, hyperactive duodenum smooth muscle is inhibitory action, and lax pipe smooth muscle is had slight enhancing contraction.(2) 1. the effect of cardiovascular system is had the asystole of the burnt short, bristly hair or beard acid of action of the heart a little less than to tired inner feelings recover to beat and the effect of mental and physical efforts, and can cause remarkable persistent coronary artery dilating effect, and strengthening the heartbeat ability, the myocardial damage that isoproterenol is caused has the certain protection effect; The arrhythmia that pituitrin is caused has certain inhibitory action, and triterpene acids energy coronary blood flow increasing improves the sensitivity of cardiac muscle to the cardiac glycoside effect, has anti-ventricular fibrillation, atrial fibrillation and falls effects such as sending out arrhythmia.2. the triterpenic acid in the burnt short, bristly hair or beard of hypotensive effect, burnt short, bristly hair or beard flavone etc. have hypotensive effect.(3) in the burnt short, bristly hair or beard of effect for reducing fat chlorogenic acid flavonoids such as (chlorogenic acid) to the cholesterol synthase vigor, serum total cholesterol, low-density lipoprotein-cholesterol and apolipoprotein B concentration have inhibitory action, can significantly reduce liver low density lipoprotein receptor mRNA level.(4) burnt short, bristly hair or beard of antioxidation and burnt short, bristly hair or beard Quercetin Flavonoid substances such as (quercetin) can show reduction serum and liver mda content, strengthen the activity of erythrocyte and liver superoxide dismutase.Strengthen the whole blood glutathione reductase activity simultaneously.(5) can increase the cell percentage of thymus and spleen weight, T lymhocyte transformation rate, T lymphocyte AMAE (+) (acid a-acetic acid how lipase) to Immune Effects; Erythrocyte C3b receptor rosette rate and erythrocyte immune complex rosette rate all had obviously increase effect, and the pair cell immunity there is facilitation with erythrocyte immune.(6) protective effect on cancer risk can be eliminated the synthetic nitrosamine of precursor substance blocking-up of synthetic nitrosamine; Mutagenic action to aflatoxin B1 has remarkable inhibition effect, can prevent hepatocarcinoma.
Poria: (1) diuresis (2) can prevent the generation of slight gastric ulcer to the effect of digestive system, and the effect of stress gastric ulcer due to the prevention of water invasion and attack is also arranged.Hepatocyte injury and alanine aminotransferase rising that carbon tetrachloride is caused have good prevention effect.(3) carboxymethyl made of antitumaous effect pachyman (pachymate) has therapeutical effect to malignant tumor such as nasopharyngeal carcinoma, gastric cancer and chronic hepatitis, also can suppress sarcoma effectively than heavy dose; The external DNA to the leukaemia of su-fuling synthesizes tangible irreversible inhibitory action, all there is obvious enhancing macrophage to produce the ability that induces tumor necrosis factor in vivo and in vitro, and since being arranged, significant dosage concerned, in vivo the transplanted tumor cell there is obvious suppression growth effect, and antineoplastic agent is had potentiation.(4) immunological enhancement pachymaran (pachymaran) has potentiation to normal and lotus tumor patient's immunologic function, can strengthen macrophage phagocytic function, make the spleen antibody secreting cell count showed increased, increase lotus tumor patient ANAE positive lymphocyte number, antagonism can make leukocyte increasing quicken because of atrophy of thymus gland and the spleen that the lotus tumor causes increases.(5) other effects have the effect that strengthens contraction and accelerate heart rate, and the contact dermatitis that staphylococcus aureus, escherichia coli, Bacillus proteus, chlorination picric acid are formed all has inhibitory action.
Fructus Jujubae: stingless Fructus Jujubae benzyl glycosides I in (1) central inhibitory action Fructus Jujubae and II, Herba Catharanthi Rosei glycosides, the emetic pure glycosides I of stingless Fructus Jujubae and II and naringenin-C-glucosides class (6,8-two-C-glucosyl group-2 (S)-naringenin and 6,8-two-C-glucosyl group-2 (R)-naringenin) have syngignoscism and strengthen the sleep effect.Wherein naringenin-C-glucosides class can reduce spontaneous activity and the reflection to stimulating, and has and cause cataleptic effect.(2) liver protection effect has liver protection effect to the hepatic model of carbon tetrachloride damage.(3) muscle strength reinforcing interaction energy weight increase prolongs swimming time.(4) to immune influence 1. anti-allergy action the fast reagin body that IgE is caused is had specific inhibitory effect, the crude polysaccharides in the Fructus Jujubae has tangible anticomplementary activity, and has concentration dependent.2. immunological stimulation Fructus Jujubae and jujube polysaccharide can improve the phagocytic rate of macrophage and the phagocytic function of phagocytic index and the interior monokaryon-macrophage system of body, promote lymphocyte transformation and improve the decomposition of periphery snow lymphocyte; Jujube polysaccharide can significantly strengthen the secretory function of M Φ to the cytotoxicity of leukemic L929 cell strain and TNF-a, IL-1, NO; Fructus Jujubae neutral polysaccharide, Fructus Jujubae crude polysaccharides, acidic polysaccharose all have the lymphopoietic effect of promotion.(5) antioxidation and old and feeble effect jujube polysaccharide, obviously slow down aging alleviates the atrophy of aging model immune organ and wearing out of brain, improves aging model blood SOD and CAT vigor, reduce brain homogenate, liver homogenate and blood plasma LPO level, have the effect of removing free radical.(6) the antitumor action Fructus Jujubae can obviously reduce glandular stomach adenocarcinoma, gastrointestinal cancer incidence rate, suppresses tumor, and sister's chromatid interchange (SCE) value that can obviously reduce caused by cyclophosphamide raises, and has antimutagenic effect.
Radix Bupleuri: (1) antiinflammatory action can obviously suppress the sufficient edema that caused by dextran, many inflammatory processes are comprised ooze out, capillary permeability, the release that causes scorching medium, leukoplania and connective tissue proliferation etc. be all influential.There are certain relation in its antiinflammatory action and pituitary adrenal axis system.(2) to central nervous system's effect 1. refrigeration function the heating that escherichia coli, expired typhoid fever polyvalent vaccine cause is had the cooling refrigeration function.2. sedation Radix Bupleuri aglycon has tangible motion to suppress and stable effect, can obviously prolong the length of one's sleep that ciclobarbital soluble causes, can also the antagonism methamphetamine, metamfetamine and caffeine be to patient's excitation.3. analgesic activity can be by the nervous analgesic activity of bringing into play of relaxing smooth muscle.4. antitussive effect Radix Bupleuri total glycosides and Radix Bupleuri glycosides soap A have stronger antitussive effect.(3) interaction energy of liver is significantly reduced the serum alanine aminotransferase (ALT) of carbon tetrachloride poisoning, the effect that slightly alleviates hepar damnification is arranged; Hepatic injury due to Typhoid Vaccine, ethanol, carbon tetrachloride, the D-galactosamine etc. there is significantly anti-damage and promotes biliary secretory action.(4), and do not resisted by atropine to the excited intestinal smooth muscle that exsomatizes of gastrointestinal interaction energy.Ethanol ulcer, harness water logging stress ulcer and pylorus ligation ulcer all there is remarkable inhibitory action.Can increase hexosamine and sialic content in mucus secretion stomach function regulating mucous membrane tissue and the gastric juice.(5) can reach part fully to Immune Effects and recover the inhibition of cyclophosphamide or influenza virus delayed hypersensitive reaction.Can obviously improve the activity of activated splenocyte conversion ratio of canavaline and natural killer cell.Thymus there is inhibitory action, causes body's immunity to reduce.(6) influence to blood fat has the high effect that refers to the mass formed by blood stasis serum cholesterol of reduction; Can increase the formation of liver fat and cholesterol; The level of plasma cholesterol, triacylglycerol and phospholipid that reduction has been raise by cholesterol.(7) antibiosis and antiviral functions has inhibitory action to growth of bacillus tubercle, plasmodium, leptospira, vaccinia virus, staphylococcus aureus and epidemic haemorrhagic fever virus.(8) antitumor action Radix Bupleuri has the rising effect to ascites tumor cell adenylate cyclase activity; Make hepatoma carcinoma cell as target cell, the result makes cancer cellular necrosis, breaks.(9) to metabolic effect because saikoside brings out cortex cholesterol secretion and low excessively with temporary transient hyperglycemia and insulin secretion, thereby suppress steatolysis and suppress the nucleus formation that insulin promotes fat, blood middle finger fat amount is reduced.
Herba Cistanches: (1) can strengthen low body fluid and the cellular immune function of yang deficiency that prednisolone produces to immune influence, strengthens monokaryon-macrophage phagocytic ability; Can significantly increase weight, enhancing macrophage phagocytic rate, increase hemolysin and hemolysis plaque value, the raising lymhocyte transformation rate of spleen and thymus.(2) adjustment endocrine, promotion metabolism can make antepituitary, ovary and uterus weight obviously increase; Ovary chorionic-gonadotropin hormone LH receptor-specific adhesion obviously improves, and the hypophysis that makes ovary is to promoting that the secretory reaction of LH obviously increases behind the luteinizing hormone releasing hormone.(3) interaction energy to the central nervous system increases the plain and 5-hydroxyindoleacetic acid content of hypothalamus adrenalectomy, and increases dopamine and dihydroxyphenyl acetic acid ratio, and reading striatum DOPAC has certain increase effect.(4) function in delaying senility can significantly improve the erythrocyte superoxide dismutase activity, and reduces lipofuscin content in the cardiac muscular tissue.D-mannitol, Herba Cistanches polysaccharides are at delaying decrepitude of skin, and the enhancing human body immunity function activates the superoxides fiery enzyme of fork and all there is significant effect the interior lipofuscin accumulation aspect of minimizing body.(5) defecating feces excretion can effectively resist atropinic inhibition defecation, and the moisture absorption to large intestine also has the obvious suppression effect simultaneously.(6) other interaction energies suppress the degeneration propagation of atherosclerosis smooth muscle cell significantly, improve its Change of Ultrastructure, reduce smooth muscle cell endoperoxides lipid content, improve its SOD activity, thereby the effect of antagonism AS in the performance, the maximum pressure that Herba Cistanches significantly reduces bladder when urinating.Herba Cistanches total glycosides is SOD of heart tissue, Se-GSH-Px activity obviously, reduces MDA content, increases perfusion back coronary flow again, reduces coronary resistance, promotes the recovery of myocardial contraction, and obviously alleviates the myocardial ultrastructure damage.
Caulis Spatholobi: (1) vasodilative effect Caulis Spatholobi water extract can make femoral artery blood flow increase.Its ethanol extraction all moves to right the amount-effect curve of vascular ring, and suppresses ceiling effect.(2) antiplatelet aggregative activity Caulis Spatholobi crude drug water decoction-alcohol sedimentation preparation has obvious inhibitory action to platelet aggregation, and stronger than Radix Angelicae Sinensis and Radix Paeoniae Rubra.(3) but the effect Caulis Spatholobi monomer component SS8 significant stimulation bone marrow depression hemopoietic progenitor cell CFU-GM of hemopoietic system, CFU-E, BFU-E, CFU-Meg growth prolongs, dosage increases in time, stimulation is strengthened gradually.Is that cell division index decline all has the rising effect to the anemia peripheral white blood cell of putting, chemotherapy causes, bone marrow nucleated cell number with grain.(4) promote that total phosphorus metabolism has facilitation to kidney in phosphorus metabolism, also can promote the total phosphorus metabolism of uterus 24h.
Colla Corii Asini: (1) has RBC number, hemoglobin and the leukocyte count of raising, promotes the effect of hemopoietic function.(2) the Antiradiation injury effect is arranged, blood hemoglobin, leukocyte count and bone marrow nucleated cell number are obviously increased.(3) can improve the phagocytic activity of peritoneal macrophage, increase the immunologic opsonin rosette forming cell and the specificity Flos Rosae Rugosae rate of spleen.(4) liver, spleen mononuclear phagocyte there are facilitation, natural killer cell activity are being shown strengthen, the healthy human lymphocyte transformation of promotion is arranged.(5) can improve hypoxia-bearing capability, strengthen the cold resistant ability, and the antifatigue effect in the swimming.(6) can promote coagulation process, clotting time be shortened play anastalsis.Can increase the people's amount of taking the photograph of calcium in the body, improve the bone calcium that causes because of calcium deficiency effectively and lose, calcium salt outflow, osteoporosis and hyperosteogeny and all kinds of fracture.(7) can make the very fast recovery of blood pressure, the blood pressure that endotoxin is caused falls, and total peripheral resistance raises, and blood viscosity rises and the bulbar Conjunctiva Microcirculation obstacle alleviates or recover normal as early as possible.(8) have the effect that the rational vascular permeability of enantiopathy increases, help microcirculatory blood perfusion and recover normal, the hematodinamics situation is improved.
Massa Medicata Fermentata: but to the effect appetite stimulator of digestive function, keep normal stool function etc.
Fructus Hordei Germinatus: (1) hypoglycemic activity can make blood glucose reduce and can lactogenic and but breast.(2) damage of antioxidation cell membrane albumen and DNA has significant protective effect, reduces the oxidation of memebrane protein and the formation of cell DNA fragmentation.Effectively the protection active oxygen is kept the normal physiological function of cell to the oxidative damage of neurocyte.(3) other interaction energies strengthen the nervous and motion in uterus, and increase with the increase of dosage.And can make it expansion; Can show the increase that reduces its serum cholesterol and triacylglycerol and lipid peroxide content, also have antifungic action.
Endothelium Corneum Gigeriae Galli: (1) is inhibitory action to the influence of animal intestines and stomach function to gastrointestinal motility, and pancreatic secretion is had facilitation, can strengthen protease, pancreatic lipase activity.(2) drainage of acceleration radiostrontium has certain effect to quickening to get rid of radiostrontium.(3) study of anti-atherogenic effect has anticoagulant and improves hemorheological effect, can alleviate the atherosclerosis degree.
Semen Raphani: (1) antimicrobial effect has remarkable inhibitory action to Portugal chrysanthemum coccus and escherichia coli.(2) hypotensive effect has significant hypotensive effect, and tremulous pulse and mean pulmonary arterial pressure, body blood vessel and pulmonary vascular resistance are obviously descended, and the pulsatility index of left ventricle and right ventricle obviously reduces.(3) influence to the harmonization of the stomach intestinal motility can strengthen the effect of ileum rhythm and pace of moving things contraction and the effect of inhibition gastric emptying, the effect that improves stomachus pyloricus ring muscle tonicity and reduce stomach bottom longitudinal muscle tonicity is arranged, obviously the inhibitory action that antiadrenergic drug is shunk the ileum rhythmicity.(4) other effects have certain antitussive, phlegm-dispelling functions.Can also treat human serum liver sterin and raise, prevent coronary atherosclerosis.
Fructus Aurantii: (1) makes heart contraction increase, weaken to the interaction energy of cardiovascular system, but hyperamization voltage rise height, the kidney volume reducing, shock has the temporary transient urine effect that presses down.(2) interaction energy to the intestines and stomach suppresses gastrointestinal motility, and contractility reduces, and tonicity descends, and ileum is shunk strengthen having antagonism.Can shorten it and move the complex wave cycle by changing the peak electrical activity of jejunum, ileum, enhancing peak electrical activity, shrink mutually the position that strengthens small intestinal, strengthens the emptying of small intestinal, the appropriate inhibitory action of drawing the faint antagonism Fructus Aurantii of energy of phenol.(3) to the effect in uterus to pregnant unpregnancy and uterus flaccidity, tangible excitation is all arranged, can make its shrink strong, tension force increases even tetanic contraction occurs.
Herba Schizonepetae: (1) analgesic cooling effect has remarkable refrigeration function to the heating due to typhoid fever, paratyphoid fever vaccine and the cholera and Typhoid-Paratyphoid A and B Vaccine and Tetanus Toxoid Complex, also has the body-temp. reducing effect.(2) sedation Herba Schizonepetae volatile oil succinic acid (succinic acid) etc. can make and movablely obviously reduce, and extremity flesh people is slightly lax, presents sedation.(3) the main constituent d-menthone (menthone) in the analgesic activity Herba Schizonepetae oil can make the pain valve improve.(4) contained benzofuranyl acrylic acid derivative has antiinflammatory action in antiinflammatory action Herba Schizonepetae volatile oil main component pulegone (pulegone), 3-capryl alcohol and nopinene and the balm flower.(5) anastalsis has remarkable anastalsis, can significantly shorten prothrombin time, thrombin time, KPTT, blood plasma recalcification time and euglobulin lysis time, and can suppress fibrinolytic.(6) to compositions such as dehydrosylvestrene in the action of the heart Herba Schizonepetae oil heart decreased heart rate and heart contractility compensatory are strengthened.The duodenum smooth muscle has stronger inhibitory action.(7) the effect Herba Schizonepetae oil of intestinal tube and uterine smooth muscle is discharged the slow reacting substance of smooth muscle inhibitory action is arranged, and can directly advance to connect the contraction of antagonism ileum, skin allergy is all had certain inhibitory action.(8) Herba Schizonepetae oil that influences to body's immunity discharges the slow reacting substance of smooth muscle inhibitory action is arranged, and the directly contraction of antagonism ileum, and skin allergy is all had certain inhibitory action.(9) antioxidation contains and can suppress the material that the brain homogenate lipid peroxide generates.(10) anti-microbial effect also has in various degree inhibitory action to dysentery bacterium, Bacillus proteus, pneumobacillus, Bacillus typhi, escherichia coli and staphylococcus aureus etc.
Herba Menthae: (1) has excited effect to central nervous system's effect to nervus centralis, makes skin capillary vascular expansion by peripheral nerve, promotes sweat gland secretion, increases heat radiation, and the effect of performance sweating and heat resolving.(2) local action can make the Cold receptor of skin mucosa produce sense of cold reflection, causes the skin mucosa vasoconstriction; Skin there is stimulation, causes long hyperemia; Simultaneously can anaesthetize teleneuron, have refrigerant, antiinflammatory, pain relieving and itching-relieving action.(3) spasmolysis menthol, menthone and ethanol extraction thereof shrink ileum inhibitory action.(4) the caused hepatic injury of hepatic cholagogic interaction energy protection carbon tetrachloride, menthol can make the active obviously reduction of alanine aminotransferase, and remarkable choleretic effect is arranged, and its main effective ingredient is a menthol.(5) antiearly pregnancy reaches the coup injury that the effect in uterus is made uterine contraction reinforcement decidua tissue, and antiearly pregnancy; Strain has inhibitory action to human cervical carcinoma cell JTC-26.(6) cardiovascular effect isomenthone Herba Menthae ketones such as (isomenthone) is had the paralysis effect to the heart, the blood vessel perfusion is had vasorelaxation action, menthone can make breathes excited, blood pressure drops.(7) interaction energy to respiratory system promotes the respiratory tract secretion, reduces secretions proportion, reduces the frothy sputum of respiratory tract, and the effective ventilation tract is increased.Can promote secretion, make the mucus dilution and the performance phlegm-dispelling functions.Can cause trachea to produce new secretion, and make stiff mucus be easy to discharge, so phlegm-dispelling functions is arranged.Good antitussive action is also arranged.(8) to suppress carrageenin foot swollen for antiinflammatory action, extract in the mentha leave with dihydroxy-1,2-dihydronaphthalene dicarboxylic acids is that the multiple composition of parent nucleus has antiinflammatory action.(9) promote the a-terpineol (a-terpineol) in the Transdermal absorption effect Herba Menthae can significantly promote the effect of acetaminophen Transdermal absorption.(10) anti-microbial effect has inhibitory action to Orphan virus, herpes simplex infections; Staphylococcus epidermidis, staphylococcus aureus, Bacillus proteus, the special bacterium of bronchus bag, micrococcus flavus, Pseudomonas aeruginosa, Bacillus cereus, Sarcina lutea, escherichia coli, bacillus subtilis, streptococcus pneumoniae, anthrax bacillus, diphtheria corynebacterium, alpha streptococcus, group B streptococcus, shigella flexneri, Bacillus typhi and Bacillus tuberculosis, Candida albicans, Penicillium, aspergillosis, Microsporon, edge spore genus and shell ball spore genus etc. all there is antibacterial action; Oleum menthae can be driven away ascarid.(11) the effect menthol to digestive system has stronger choleretic effect.(12) other effects have obvious protective effect to skin lesion due to the lonizing radiation.
Caulis Perillae: (1) pregnancy hormone like-effect can make endometrial thickness, promotes the hypertrophy of endometrial gland.(2) the perilla ketone compositions such as (perillaketones) of other effects in Caulis Perillaes can suppress 1 type cyclooxygenase activity and cure mainly regulating the flow of QI to ease the stomach, and be antiabortive, and blood.
Radix Gentianae Macrophyllae: the water extract of (1) antiinflammatory action Radix Gentianae Macrophyllae, gentiana crassicaulis Duthie, Flos Cannabis Macrophylla and alcohol extract have significant antiinflammatory action to claw swelling due to ear's swelling of Fructus Crotonis oiliness and the carrageenin, wherein three kinds of Radix Gentianae Macrophyllae of Fructus Crotonis oiliness ear swelling are all had remarkable result, for the carrageenin swelling of the feet only gentiana crassicaulis Duthie remarkable result is arranged.(2) analgesic activity gentiana crassicaulis Duthie, gentiana straminea maxim all have remarkable analgesic effect, but the strongest with the effect of gentiana crassicaulis Duthie.(3) to the blood pressure drops that gentianin can cause anesthesia person that influences of heart and blood pressure, simultaneously visible decreased heart rate, effect strengthens because of dosage.Because gentianin has stronger heart inhibitory action, can make decreased heart rate, and auxocardia is incomplete, output reduces, and the mechanism of blood pressure lowering may be the direct inhibition to heart.
The Radix Angelicae Dahuricae: (1) analgesia, loyal quiet effect can suppress autonomic activities.(2) the antipyretic and anti-inflammatory interaction energy suppresses ear's inflammation.(3) photosensitization suppresses contact dermatitis, can add the effect of intensive ultraviolet to skin.(4) can suppress the melanoma cells melanocyte to skin, hair influence and form, the antenna hair follicle is had growth promoting function.(5) function of tumor inhibition can suppress the HeLa cell phospholipid effect that 32Pi that tumor promoter TPA promotes mixes, can inducing leukemia cell HL-60 apoptosis.(6) anti-microbial effect has antibacterial action, and the urogenital tract mycoplasma hominis is had than hypersensitivity, can suppress the schizotrypanum cruzi crithidial stage, can suppress hepatomicrosome cytochrome and hormonal hydroxylase activity.(7) influence to liver drug enzyme suppresses the small intestinal normal activity, and antagonism physostigmine etc. causes the contraction of the tetanic property of intestinal smooth muscle, and hepatoprotective effect is arranged.
Radix Asteris: (1) phlegm-dispelling functions can increase the phenol red drainage of respiratory tract.(2) to have cough-relieving to do useful for the cough that ammonia or sulfur dioxide are caused of antitussive, antiasthmatic effect, and cough has antitussive effect to ammonia, and the isolated tracheal that histamine is caused shrinks inhibitory action is arranged.(3) antitumor action suppresses sarcoma S180 growth, and growth has inhibitory action to the P338 Lymphocytic leukemia.(4) the anti-clonorchis sinensis of other interaction energies can press down the generation and the erythrocyte hemolysis of lipid peroxidation, free radical, Wheat Protein.
Bulbus Fritillariae Uninbracteatae: (1) significantly increases the phenol red excretion amount of respiratory tract to the interaction energy of respiratory system, and fritimine has obvious phlegm-dispelling functions.(2) the hypotensive effect fritimine can cause blood pressure drops, and suppresses with transitory respiration, also can cause the peripheral blood vessel expansion.(3) to the influencing Bulbus Fritillariae Cirrhosae 0 alkali and can cause uterine contraction of smooth muscle, suppress small intestinal and shrink, fritimine can make blood glucose increase, and can obviously strengthen hypoxia-bearing capability, suppresses the star-shaped nocardia growth.
Radix Platycodonis: (1) eliminates the phlegm and antitussive effect can increase respiratory tract mucus secretory volume, and phlegm-dispelling functions is arranged.(2) platycodin A, C, the D[1 in the antiinflammatory action Radix Platycodonis], the foot swelling due to D2, D3 on Carrageenan and the acetic acid has antiinflammatory action, the permeability and the granuloma induced by implantation of cotton pellets of the blood capillary that anaphylactic shock is caused are remarkable inhibitory action; And it is also effective to arthritis.The extract of Radix Platycodonis can strengthen phagocytic function, and the sterilizing power of neutrophilic leukocyte improves activity of lysozyme.(3) platycodin A, C, the D[1 in the antiulcer action stalk short of money], D2, D3 have gastric secretion, the anti-effect that consumes the gastric secretion due to voltinism ulcer and the pylorus ligation of suppressing, the chronic ulcer due to the Dichlorodiphenyl Acetate has obvious curative effects.(4) interaction energy to cardiovascular system reduces hind leg blood vessel and resistance coronarius, blood flow increasing.To isolated atria, contractility is weakened, decreased heart rate, but can resist the atrium inhibition that Ach causes.(5) hypoglycemic activity can make four itch pyrimidine diabetes and food blood glucose descend.(6) interaction energy to nervus centralis suppresses voluntary activity, prolongs the length of one's sleep of ciclobarbital soluble, presents tangible sedation; Dichlorodiphenyl Acetate writhing response and tail platen press are analgesic activity, and the heating to due to typhoid fever, the paratyphoid fever vaccine all has the effect of significant reduction body temperature.(7) platycodin A, C, the D[1 of other effects in Radix Platycodoniss], D2, D3 can reduce the content of liver inner cholesterol, increases the drainage of steroid and cholic acid; The congested edema that ligation causes to the bilateral jugular vein has edema and diuresis, can obviously promote the growth of photosynthetic bacteria, and lixiviating solution concentration is higher, and the short fruit of coming into force is healed obviously.
Radix Rehmanniae Preparata: the leukopenia that (1) causes cyclophosphamide and actinotherapy immune effect Fructus Corni has impels its rising effect, can strengthen humoral immune function, promote normal with stress due to immunologic hypofunction and cyclophosphamide cause that the hemolysis plaque that immunologic function suppresses forms cell number, and can regulate the downtrod SDH of immunosuppressant cyclophosphamide (cellular immunization) and return near normal level.The Fructus Corni saccharide also has the immunoreactive effect of obvious promotion, and the Fructus Corni water decoction is irritated stomach has certain potentiation to humoral immunization, but weakens the T lymphocyte function.(2) footpad swelling that antiinflammatory action Fructus Corni decoct can suppress that the abdominal cavity capillary permeability that acetic acid causes increases, auricle swelling and Ovum Gallus domesticus album cause due to the cott on pellet-induced granuloma formation, dimethylbenzene and synovium of joint cell are to the chemotactic of inflammatory cell, Fructus Corni total glycosides can reduce the infiltration of inflammatory cell to synovium of joint, and arthritis is had therapeutical effect; Can also reduce content of ascorbic acid in the adrenal gland.(3) the effect Fructus Corni injection of hemorrhagic shock there is the effect of the blood pressure that raises rapidly and obviously to hemorrhagic shock due to the blood-letting, can prolongs life span.(4) cornusol that influences to blood glucose does not have influence to euglycemia, but to alloxan and the obviously blood sugar lowering effect of epinephrine glycosuria disease.Can significantly increase diabetic vascular complications model SOD in serum value, the oxidative stress damage that is caused by diabetic vascular complications is had protective effect, iridoid glycoside is also had protective effect to diabetes thoracic aorta blood vessel endothelium.(5) to cardiac function and hemodynamic influence to the influence of cardiac function, hematodinamics and cardiac work thereof and oxygen consumption index, show to strengthen cardiac pumping function, make hypertension.(6) the high low dose group of antiarrhythmic effect Fructus Corni all can obviously prolong the ARR incubation period that aconitine brings out, reduce the incidence rate and the mortality rate that quiver in the calcium chloride chamber of causing, obviously improve left chamber papillary muscles that aconitine and calcium chloride brings out and shrink arhythmicity reverse effect is arranged.(7) the effect Fructus Corni injecting fluid external administration of anticoagulant can obviously suppress the platelet aggregation of threshold concentration adenosine diphosphate (ADP) (ADP) sodium salt, collagen or arachidonic acid-induction and the thrombosis of common carotid artery-external jugular vein bypass circuit.(8) other effect Fructus Corni decocts can be killed ascites cells external, and the effect of anti-experimental character hepatic injury is arranged.Can significantly suppress Aspartic Acid aminotransferase, alanine aminotransferase.Diuresis is arranged, and blood pressure is reduced, can obviously increase content of hemoglobin, physical strength reinforcing and resisting fatigue, anoxia enduring and memory reinforcing.Can make the insufficiency of kidney-YANG liver weight near normal, hepatocyte pathology changes and alleviates, and hepatocyte RNA and glycogen content raise, and mda content descends.The testis organ coefficient is reversed to normal direction, make rna content increase in the interstitial cell.
Fructus Corni: the leukopenia that (1) causes cyclophosphamide and actinotherapy immune effect Fructus Corni has impels its rising effect, can strengthen humoral immune function, promote normal with stress due to immunologic hypofunction and cyclophosphamide cause that the hemolysis plaque that immunologic function suppresses forms cell number, and can regulate the downtrod SDH of immunosuppressant cyclophosphamide (cellular immunization) and return near normal level.The Fructus Corni saccharide also has the immunoreactive effect of obvious promotion, and the Fructus Corni water decoction is irritated stomach has certain potentiation to humoral immunization, but weakens the T lymphocyte function.(2) footpad swelling that antiinflammatory action Fructus Corni decoct can suppress that the abdominal cavity capillary permeability that acetic acid causes increases, auricle swelling and Ovum Gallus domesticus album cause due to the cott on pellet-induced granuloma formation, dimethylbenzene and synovium of joint cell are to the chemotactic of inflammatory cell, Fructus Corni total glycosides can reduce the infiltration of inflammatory cell to synovium of joint, and arthritis is had therapeutical effect; Can also reduce content of ascorbic acid in the adrenal gland.(3) the effect Fructus Corni injection of hemorrhagic shock there is the effect of the blood pressure that raises rapidly and obviously to hemorrhagic shock due to the blood-letting, can prolongs life span.(4) cornusol that influences to blood glucose does not have influence to euglycemia, but to alloxan and the obviously blood sugar lowering effect of epinephrine glycosuria disease.Can significantly increase diabetic vascular complications model SOD in serum value, the oxidative stress damage that is caused by diabetic vascular complications is had protective effect, iridoid glycoside is also had protective effect to diabetes thoracic aorta blood vessel endothelium.(5) to cardiac function and hemodynamic influence to the influence of cardiac function, hematodinamics and cardiac work thereof and oxygen consumption index, show to strengthen cardiac pumping function, make hypertension.(6) the high low dose group of antiarrhythmic effect Fructus Corni all can obviously prolong the ARR incubation period that aconitine brings out, reduce the incidence rate and the mortality rate that quiver in the calcium chloride chamber of causing, obviously improve left chamber papillary muscles that aconitine and calcium chloride brings out and shrink arhythmicity reverse effect is arranged.(7) the effect Fructus Corni injecting fluid external administration of anticoagulant can obviously suppress the thrombosis of threshold concentration adenosine diphosphate (ADP) (ADP) sodium salt, collagen or the flower inductive platelet aggregation of tetraenoic acid and common carotid artery-external jugular vein bypass circuit.(8) other effect Fructus Corni decocts can be killed ascites cells external, and the effect of anti-experimental character hepatic injury is arranged.Can significantly suppress Aspartic Acid aminotransferase, alanine aminotransferase.Diuresis is arranged, and blood pressure is reduced, can obviously increase content of hemoglobin, physical strength reinforcing and resisting fatigue, anoxia enduring and memory reinforcing.Can make the insufficiency of kidney-YANG liver weight near normal, hepatocyte pathology changes and alleviates, and hepatocyte RNA and glycogen content raise, and mda content descends.The testis organ coefficient is reversed to normal direction, make rna content increase in the interstitial cell.
Fructus Lycii: (1) is dual regulation to the lycium barbarum polysaccharide in the Immune Effects Fructus Lycii (LBP) to T, the bone-marrow-derived lymphocyte factor, macrophage C3b and Fc acceptor quantity and vigor can be increased significantly, and the inhibitory action of hydrocortisone acetate can be weakened macrophage C3b and Fc receptor.(2) function in delaying senility can improve the lymphocytic propagation function of splenic T, strengthen the killing ability of cytotoxic T cell (CTL), can resist the immunosuppressive action of cyclophosphamide (CY), also have tangible anti-X-radiation effect T lymphocyte, CTL and natural killer cell (NK carefully relaxes).LBP can significantly promote splenocyte propagation, and delaying senility function is arranged.(3) antitumor action has the mutation inhibiting effect to the inductive mutant TA98 of carcinogen, TA100, resists, blocks mutagenic action so Fructus Lycii contains antimutagen and has.People's adenocarcinoma of stomach KATO-III cell is had obvious inhibitory action, and its mechanism of action shows that mainly suppressing cell DNA synthesizes, the interference cell division, and cell is grown ability drop again.(4) blood fat reducing with protect the liver, lipotropy has the effect that reduces serum total cholesterol (TC), triacylglycerol (TG), low-density lipoprotein cholesterol (LDL-C) in the blood and the effect that reduces TC, TG in the liver; The hepatic injury that carbon tetrachloride is caused has slight inhibition fat to deposit and promote hepatocyte new life's effect in hepatocyte, to the protection effect of carbon tetrachloride poisoning hepatitis.(5) LBP that influences to hemopoietic system has facilitation to normal hemopoietic function, can make leukocytosis; Can promote splenic T lymphocytic emiocytosis colony stimulating factor, improve the serum colony stimulating activity.(6) anti-hereditary material damaging action can reduce the heart, brain, skeletal muscle tissue mitochondrial DNA deletion, improves synthetic and the heart, skeletal muscle mitochondrial respiratory chain compound enzyme IV vigor and the brain mitochondria respiratory chain compound enzyme I vigor of the heart, brain mitochondria adenosine triphosphate (ATP); Ametycin is brought out the antagonism of micronucleus, and Fructus Lycii has tangible anti-ametycin and brings out the micronucleus effect.(7) hypoglycemic activity lycium barbarum polysaccharide (LBP) can make blood glucose obviously reduce, and the hyperglycemia level also obviously reduces.(8) hypotensive effect reduces the high blood systole of kidney, diastolic blood pressure, reduces malonaldehyde in blood plasma and the blood vessel, and content of ET increases the release of calcitonin-gene-related peptide.(9) bacteriostasis to staphylococcus aureus, staphylococcus epidermidis, micrococcus lysodeikticus bacterium, Bacillus typhi II-901, Bacillus typhi O-901, paratyphoid bacillus A, Bacillus paratyphosus B, Bacillus paratyphosus C, Bacillus typhi, dysentery bacterium, escherichia coli, aerobacteria, Pseudomonas aeruginosa, bacillus subtilis, anthrax bacillus (avirulent strain), epidemic disease bacillus (avirulent strain), read 17 kinds of antibacterials such as coccus in vain stronger inhibitory action all arranged.(10) other interaction energies promote the growth of lactobacillus, and stimulate it to produce acid; Skin hydroxyproline content is increased, can strengthen hypoxia-bearing capability and prolong swimming time.
Carapax et Plastrum Testudinis: (1) reduces the content of T3, T4 in the hyperthyroidism serum to the influence of thyroid function, erythrocyte membrane Na+, K+-ATP enzymatic activity, plasma cAMP and blood plasma viscosity, reduce whole oxygen consumption, rising blood glucose improves the threshold of pain, decreased heart rate, amount of drinking water reduces, increase the urine amount, weight increase, thus make the atrophy thyroid recover growth.(2) can impel peritoneal macrophage quantity to increase to the Immune Effects Colla Plastri Testudinis, volume increases, pseudopodium increases, improve cellular immunization and humoral immune function, (3) influence to adrenal gland's function can make adrenal cortex recover growth, the cortex glomerular zone thickens, and zona fasciculata unit are cell number reduces, and reduction adrenal cortex can be arranged with putting.(4) the Carapax Et Plastrum Testudinis decoct that influences to the uterus has tangible excitation to the uterus.(5) influence to trace element can make serum copper and copper/zinc ratio descend.(6) function in delaying senility can promote the growing multiplication of In vitro culture the 35 generation human embryonic lung diploid fibroblast (2Bs cell), shows that pair cell has function in delaying senility.(7) influence to osteogenesis can reduce the urinary hydroxyproline excretion, bone density improving and bone calcium, content of magnesium, and make Serum alkaline phosphatase activity that rising trend be arranged.(8) to the effect Carapax et Plastrum Testudinis of neural stem cell to focal cerebral ischemia after neural stem cell the promotion proliferation function is arranged, can alleviate the nerve injury symptom.
Fructus Ligustri Lucidi: (1) antiinflammatory action all has obvious inhibitory action to the stupid auricle swelling that causes of diformazan, abdominal cavity capillary permeability increase that acetic acid causes and on Carrageenan, Ovum Gallus domesticus album, formaldehyde rat paw edema.Can significantly reduce the burst size that inflammation is organized prostaglandin, suppress cott on pellet-induced granuloma formation, simultaneously with the increase of, adrenal gland's weight.The effective content of anti inflammation of Fructus Ligustri Lucidi is an oleanolic acid.(2) the Immune Effects Fructus Ligustri Lucidi there is the effect that promotes immunologic function, gland spleen weight is increased.Fructus Ligustri Lucidi is external in vivo all to have facilitation to lymphocyte transformation.(3) allergic inhibitory action Fructus Ligustri Lucidi had obvious inhibitory action to I, III, IV allergic reaction type.(4) to a kind of colourless prismatic crystalline lens in influence (5) the hypoglycemic activity Fructus Ligustri Lucidi of lipid metabolism, has the good stable hypoglycemic activity.(6) the neat fruit acid of hepatoprotective effect has significant protective effect to the acute liver damage that carbon tetrachloride causes, can reduce accumulating of the interior triacylglycerol of serum alanine aminotransferase and liver, promotes liver cell regeneration, prevents hepatitis interstitialis chronica.(7) influencing the Fructus Ligustri Lucidi medicinal liquid and can promote hemopoietic progenitor cell of red blood cell line growth hemopoietic system, to grain is that CFU-GM but significantly reduces, medullary cell morphology shows red system propagation greater than grain system, and myeloid erythroid is respective change also, illustrates that Fructus Ligustri Lucidi has facilitation to erythroid hematopoiesis.To chemotherapy or caused by radiation leukopenia, the rising effect is arranged.(8) antimutagenic and anti-hematoporphyrin derivative (HPD) photooxidation Fructus Ligustri Lucidi decoct have the effect that micronucleus raises due to the different originality of resistance, cyclophosphamide and the urethane.(9) extractive with organic solvent that influences Fructus Ligustri Lucidi to gonadal hormone can make the large follicle number that tangible increase is arranged, and estrogen raises.
Herba Epimedii (1) sexual function improving influences reproduction and hormonal system icariin (ICA) the cavernous body of penis smooth muscle that can relax, and it is relevant that this strengthens the NO-CGMP activity with suppressing the V-type phosphodiesterase activity.Can increase weight such as Prostato-Seminal vesicle, uterus, adrenal gland, thymus and testosterone, estradiol level.The external promotion of ICA rat follicular cell secretion estradione, high concentration promote adrenal cortical cell secretion corticosterone.ICA irritates the resistance thyroid effect of stomach antagonism propylthiouracil (PTU).(2) the slow down aging Herba Epimedii is irritated stomach, and having has protective effect to mitochondrial oxidative damage, improves oxidation resistances such as erythrocyte, hepatic tissue.(3) regulate immunologic function arrow leaf Folium Epimedii extract and irritate the phagocytic function that stomach promotes reticuloendothelial system, activate the phagocytic activity of liver KUPFFER cell.(4) the effect Herba Epimedii extract intravenous drip to cardio-cerebrovascular can reduce total peripheral vascular resistance of people and left chamber EDP, increases crown arteries and veins blood flow, cardiac output etc.(5) prevent and treat osteoporosis; promote the union of fracture Herba Epimedii total flavones to promote people's skeletonization like cell OS732 propagation and differentiation outward; osteoporosis due to the control prednisolone acetate; the effect of protection gonad, inhibition bone resorption, promotion bone formation and inhibition bone loss is arranged; promote VEGF, transforming growth factor to express accelerating bone healing.
Rhizoma Curculiginis: (1) can promote the multiplication capacity and the phagocytosis of peritoneal macrophage to Immune Effects curculigol preserved material.The Rhizoma Curculiginis polysaccharide is external can induce spleen lymphocyte proliferation separately.(2) to the interaction energy of hypothalamic pituitary gonadal axis function antepituitary, ovary and uterus weight are all obviously increased the influence (1) of reproductive function; 2. the effect of androgen sample can make seminal vesicle obviously increase weight; 3. improve the sperm motility ability.(3) adapting to the former state effect can obviously prolong the anoxia enduring time-to-live, and the high temperature resistance effect is arranged.(4) acetone extract of other effect Rhizoma Curculiginises has blood sugar lowering and active anticancer, can obviously prolong the length of one's sleep, also can obviously delay the twin property convulsions time of occurrence of battle array.
Colla cornus cervi: sexual function improving can shorten the incubation period of the erection of electric stimulus inducing, and Colla cornus cervi has enhancing trend to mating ability, and seminal fluid capsule and prostate are had effect of gain.
Os Draconis: the weight of (1) enhance immunity and the repair can increasing of promotion damaged tissue thymus and spleen, increase the phagocytic activity of mononuclear phagocyte to serum carbon, reduce injury of sciatic nerve.(2) sedation can increase pentobarbital sodium hypnosis rate, has certain analgesic activity.
Radix Ginseng: (1) to the effect Radix Ginseng of nervus centralis and different preparation thereof, heterogeneity, and central nervous system's physiological function is had regulating action.1. to the regulating action of nervus centralis in Radix Ginseng, extract a kind ofly contain glucose, rhamnose saponin B has tangible sedation; The central nervous system is had inhibition, stable, sedation to Radix Ginseng GNS and central is of flaccid muscles, cooling, reduce effects such as voluntary activity; The then excited cerebral cortex of the hydroalcoholic extract of Radix Ginseng, the excitement of enhancing cerebral cortex is reacted with the activity of process of inhibition, strengthens the cholinergic nerve function, and makes blood pressure drops, breathing excitement.Radix Ginseng has the central excitation effect to central nervous system's excitement and the two-way function that suppresses as ginsenoside Rg's class, and the Rb class then presents sedation.2. influence Radix Ginseng and the preparation thereof to learning and memory improving learning capacity, and there is obvious facilitation facilitation memory aspect, and going down of learning behavior had preventive effect.3. the Radix Ginseng that influences to material in the brain all has facilitation to proteinic synthetic, RNA and DNA synthetic, and monoamines material and acetylcholine system work to maincenter in the brain by influencing.4.) influencing the ginsenoside and can significantly stop cerebral ischemia and refilling process mediopellis electroencephalogram generation severe inhibition and cerebral edema to form cerebral blood flow and brain energy metabolism.The ginsenoside can increase ischemia and pour into cerebral blood flow again, reduces the calcium accumulation, alleviates cerebral edema, prolongs bilateral clavicle autonomous respiration and brain electrical acti time down and after the common carotid artery ligation, and recovery when promoting to pour into again.(2) 1. the influence to body's immunity all has tangible activation to the ginsenoside that influences of reticuloendothelial system phagocytic function to multiple reticuloendothelial system phagocytic function, can strengthen it to colloid carbon granules, staphylococcus aureus, the erythrocytic ability of cleaning up of engulfing in the blood flow.Can increase the weight of immune organ and the phagocytic function of macrophage.2. the effect that influences Radix Ginseng polysaccharide promotion body specific immunity that specific antibody is formed can make the content of specific antibody IgH in the erythrocyte immune serum obviously raise.3. the ginsenoside that influences that lymphocyte is shifted has significant potentiation to the lymphocyte transformation that bacteria lipopolysaccharide and concanavalin A stimulate; Lymphproliferation response facilitation to various mitotic primary stimulis is the most obvious.The ginsenoside stimulates lymphocyte transformation that tangible potentiation is also arranged to the external concanavalin A that the immunity due to the Rd Dichlorodiphenyl Acetate prednisolone is subjected to press down, and can make it return to normal level fully.4. can strengthen lotus tumor natural killer cell activity to tumor animal Immune Effects ginsenoside, suppress the weight of tumor piece, and the obvious hypertrophy of lotus tumor spleen, thymus obviously dwindles, and the load-bearing ratio of outflow is reduced.(3) the arrhythmia effect that 1. can have stronger anti-barium chloride to bring out to the influence of heart to the effect of cardiovascular system is corrected tachycardia, and is made it return to normal level.Panoxadiol's saponins is amphicheirality's effect to the myocardial cell action potential; To myocardial ischemia be perfused with protective effect again.2. to the influencing the ginsenoside blood pressure is reduced of blood vessel and blood pressure, can make the kidney vasoconstriction, significantly improve renal vascular resistance.And femoral artery, vertebral artery and renal artery vascular resistance are reduced.3. Antishock function has significant protective effect to the hemorrhagic shock cardiac function, strengthens myocardial contraction, improves hemodynamic state; The increase of norepinephrine and DOPAMINE CONTENT IN RABBIT suppressed the release of shock stage platelet to 5-HT when Panaxadiol saponin can stop shock simultaneously.4. to the flowability increase that the ginsenoside can make inmature and mature erythrocyte film that influences of blood and hemopoietic system, erythrocyte membrane there is protective effect; Also have direct stimulation CFU-E proliferation function, the mechanism of action of Radix Ginseng total saponins may be to promote bone marrow hematogenesis indirectly by the activity that strengthens hematopoietic growth introduction such as erythropoietin.Also has the effect of anticoagulant and reduction blood coagulation.(5) to 1. influencing Radix Ginseng total saponins and can increase the long gland 17-hydroxy-11-dehydrocorticosterone secretion of kidney of the effect of hormonal system to hypophysis-interrenal system.2. the influence to gonad can make growing animal uterus and ovary weight increase, and quickens its sexual maturity process, and its thing is prolonged rutting period; Radix Ginseng can hypophysis secretion promoting sexual gland hormone.3. can make the antepituitary thyrotropin discharge increase to other eccrine panaxynol extracts that influence.Can stimulate the islets of langerhans uelralante, and the insulin that can promote glucose to cause discharges.(6) 1. the influence to substance metabolism can reduce euglycemia or hepatic glycogen to the glycometabolic ginseng polypeptide that influences, and the hyperglycemia that epinephrine, alloxan and glucose are caused all has inhibitory action, and can strengthen the decomposition of epinephrine to hepatic glycogen.2. the Radix Ginseng extract that influences to lipid metabolism has inhibitory action to fatty liver and hyperlipidemia; The intravital serum triacylglycerol of diabetics, very low density lipoprotein (VLDL), free fatty, T-CHOL and ketoboidies are reduced, the cholesterol of high density lipoprotein raises, atherogenic index reduces, cholesterol there is disassimilation and promotes Excretion, can promote that triacylglycerol changes in the fatty tissue.3. proteometabolic influence there is facilitation to nucleic acid and proteinic synthesizing; Radix Ginseng component GN3 and GN4 make the active increase of dna dependent rna polymerase in the liver cell nuclear, promote the orotic acid of labelling to mix in the hepatocyte nRNA, cause the synthetic increase of rough endoplasmic reticulum film attached type polysome and secretary protein.(7) antitumor action Leptoradix Ginseng syrup can make the hepatocarcinoma incidence rate reduce, and promotes the body cell immunity, and the hepatocarcinoma that chemical carcinogens is brought out has prevention or control action.Glycol saponins Rb2 has very high anti-tumor activity, to tumor have that induction, propagation suppress, inducing cell transfers effect such as die.Reduce the chromosome aberrations rate that X ray brings out, thereby reduce the side effect and the toxic action of antineoplastic radiation and chemotherapy.(8) delaying senility function suppresses erythrocytic haemolysis and membrane lipid peroxidation, has the free radical of removing function and the erythrocytic effect of protection.Can increase liver endochylema glutathion peroxidase and catalase activity, thereby the body hydrogen peroxide is removed.The Radix Ginseng decoction has function in delaying senility.(9) other effects ginsenoside can obviously suppress the withdrawal symptom of morphine, the ginsenoside can block the generation of the metabolite hydromorphone of morphine effectively, improve the level of glutathion in the liver, remove the inhibition of morphine to release neurotransmitters in the brain, thereby prevent morphine toleration and addiction, alleviate withdrawal symptom.
Tremella: can promote the immunologic function hemolysin to form, can improve the splenocyte increment, strengthen splenocyte IL-2, splenocyte is grown up.Effect strong essence, the kidney invigorating, lung moistening, promote the production of body fluid, cough-relieving, heat clearing away, nourishing the stomach, QI invigorating and blood, heart tonifying, strong body, supplementing the brain, refresh oneself, cure mainly cough due to consumptive disease, dry cough less thirsty, the constipation with dry stool of expectorant, sputum mixed with blood, deficiency-heat, have blood in stool, hypertension, sclerosis of blood vessels, leukopenia, retinal hemorrhage and menorrhagia.
Rhizoma Cimicifugae: (1) is analgesic, the Hesperetic acid compositions such as (isoferulic acid) in the cooling effect Rhizoma Cimicifugae can make normal body temperature reduce, and heating due to the typhoid fever mixed vaccine is also had refrigeration function.(2) analgesic activity.Can obviously suppress writhing response due to the acetic acid, have that analgesic activity (3) is calm, anticonvulsant action Rhizoma Cimicifugae decocting liquid can make autonomic activities reduce, present sedation, dahurinol has inhibitory action to fainting from fear due to Camphora or the strychnine. and (4) antiinflammatory action rhizoma cimicifugae dahuricae and active ingredient Hesperetic acid (isoferulicacid) have inhibitory action to foot swelling, to lactic acid or the caused anal ulcer of acetic acid, make the ulcer area dwindle trend.(5) can strengthen lymphocytic activity to Immune Effects Xingan Rhizoma Cimicifugae deanol triterpenoid compound such as (cimicidanol), the lymphocyte transformation that phytohaemagglutinin (PHA) is caused has very strong inhibitory action, cimigenol xyloside can optionally suppress to take in the cell nucleoside simultaneously, suppress lymphocytic activation, can also produce interferon by induction of lymphocyte.(6) liver protection effect cimigenol xyloside etc. has the obvious suppression effect to hepatic injury, serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) value is obviously reduced, and hepatocellular degeneration, necrosis are alleviated.(7) 50% methanolic extract of spasmolysis rhizoma cimicifugae dahuricae rhizome can shrink the jejunum that anti-acetylcholine, histamine, barium chloride cause, part causes the convulsion effect to the jejunum intestinal tube.(8) the antivirus action Rhizoma Cimicifugae has inhibitory action to myenteron and gravid uterus, and unpregnancy uterus and bladder are hormesis, also has antivirus action.(9) suppress nucleoside running Rhizoma Cimicifugae promise alcohol (cimicinol)) wait triterpenoid compound can suppress the transhipment of the lymphocytic nucleoside of phytohaemagglutinin (PHA) stimulation, the lymphocyte that external PHA stimulates is to the transhipment of thymidine, and external inhibited to simian immunodeficiency virus (SIV).The different Xingan of anti-sclerotin osteoporosis effect cimicifugol. (isocdahurinol)) etc. (10) triterpenoid compound induces ovariectomized osteoporosis inhibited to parathyroid hormone (PTH), and going through the osteoporosis of having guided by PTH when osseous tissue is cultivated also has very strong inhibitory action.(11) organic acid D in the vasodilator effect Rhizoma Cimicifugae and fukinolic acid can continue and aorta that lax lentamente norepinephrine (NE) causes shrinks, and suppress stream in the Ca2+.
Herba Patriniae: (1) sedation, the root of Patrinia scabiosaefolia Fisch and rhizome ethanol or methanol extractum can make movable the minimizing, be rest state, and the length of one's sleep of significant prolongation pentobarbital sodium or ciclobarbital soluble, but the clear aminotransferase rising of methanolic extract hyperamization regulating liver-QI histo pathological change.Can make righting reflex loss, illustrate that sedation is direct central action.And Hemerocallis citrina Baroni dragon bud essence is the main effective ingredient of its sedation.(2) antibiotic, antivirus action has stronger inhibitory action to staphylococcus aureus and I herpes simplex virus type, the inhibitory action of shigella, Bacillus typhi and Staphylococcus albus a little less than.(3) the hepatic cholagogic effect has the effect that promotes liver cell regeneration, prevents hepatocellular degeneration, but and hepatitis virus resisting, the hepatocyte inflammation is disappeared, the bile capillary mediation is improved liver function.Simultaneously can also promote bile secretion, isolated saponin can improve the activity of serum aminotransferase.(4) leukocyte count that the interaction energy of blood system is obviously resisted caused by cyclophosphamide reduces, and stimulates hemopoietic function of bone marrow, and its function of increasing leukocyte and adenine phosphate, batilol are close.(5) other 100% Herba Patriniae liquid add the 10mg endotoxin, can reduce its activity, and the attenuation multiple is 8.7.
Tiger zhang: (1) to the effect of cardiovascular system tiger zhang glycosides can by direct reduction white to blood vessel endothelium adhesion and microcirculation improvement, effect with ATP sensitive potassium channel, may expand arteriole by making arteriole smooth muscle hyperpolarization, thereby send the shock animals microcirculation.Calcium, PH have dual regulation in the tiger zhang glycosides pair cell, can strengthen myocardial contractility by increasing myocardium free calcium concentration, and its effect may be open relevant with the calcium sodium channel.(2) effect for reducing blood fat tiger zhang listens polydatin and resveratrol can reduce the level of aspartic acid based transferase and alanine aminotransferase in the serum, reduce lipid peroxide and reduce the free serum fatty acid, stop lipid peroxide to be induced by microsome in the liver and NADPH. (3) influence polydatin and can suppress the inductive platelet aggregation effect of AA, ADP significantly platelet aggregation.(4) the antioxidation polydatin has very strong inhibitory action to the lipid peroxidation that radical generating system causes, the liver protecting function is arranged, and suppresses the accumulation of LPO at liver.(5) brave zhang of antibiotic, antivirus action has good inhibition effect to Pseudomonas aeruginosa, shigella flexneri and the thunder utmost point one Pu Luoweideng bacterium, Coxsackie virus there is certain direct killing action, but can not block Coxsackie virus absorption sensitive cells, think that can cross direct kill virus for brave zhang brings into play its anti-Coxsackie virus effect with an inhibition viral organism Synthetic 2 link.(6) an antitumor action tiger zhang decoct has inhibitory action to ehrlich carcinoma, and resveratrol has inhibitory action to the hepatoma carcinoma cell of In vitro culture, and mechanism may be liver cancer apoptosis reducing.
Radix Isatidis: (1) antibacterium virus function Radix Isatidis has bacteriostasis to staphylococcus aureus, staphylococcus epidermidis, hemorrahgic fever with renal syndrome virus, herpes simplex virus are had tangible killing action, and can suppress influenza A virus, encephalitis b virus, mumps virus, influenza virus is infected and the inhibition proliferation function is arranged.(2) the anti-endotoxin effect Radix Isatidis has Chinese People's Anti-Japanese Military and Political College's enterobacteria endotoxin effect.(3) antitumaous effect has powerful direct killing effect to erythroleukemia cell, solid tumor there is certain therapeutical effect, Radix Isatidis diketone B has the ability that suppresses hepatoma carcinoma cell, ovarian cancer cell propagation, and has induction of differentiation, can reduce the expression of telomerase activation, have anti tumor activity in vitro.(4) can obviously strengthen delayed allergy to immunoregulation effect, the natural killer cell activity of cell transformation of inductor endolymph and enhancing splenocyte.Can promote immunologic function, suppress delayed hypersensitivity.In addition, can also strengthen antibody forming cell's function, increase quiet notes charcoal and clean up speed.
Bombyx Batryticatus: (1) anticonvulsant action can resist the tonic convulsion that brucine causes, reduces death toll.(2) antitumor action has inhibitory action to sarcoma.(3) bacteriostasis all has more weak inhibitory action to antibacterials such as staphylococcus aureus, escherichia coli, Pseudomonas aeruginosas.
Carapax Trionycis: (1) blood tonification effect can make content of hemoglobin obviously increase.(2) antitumor, antimutagenic effect are inhibited to cancer MHI3, and diameter of tumor is reduced, and tumor weight alleviates.Tumour inhibiting rate to colon-cancer cell is 92.15%, and the neoplasm necrosis area reaches 67%, and turtle ' s carapace powder has inhibitory action to intestinal cancer, few side effects, to the inhibition of bone marrow more than the light L3 of 5-Fu.Carapax Trionycis and Carapax et Plastrum Testudinis have antimutagenic activity.(3) to the liver fiber HYP content is obviously reduced.(4) other interaction energies reduce swimming bleeding from anus lactate level effectively and improve blood lactic acid regeneration rate, prolong swimming time, can significantly improve cellular immune function, and abdominal cavity M φ phagocytic function and the cell transformation of spleen crust are reacted all to show than matched group and strengthened.
The Radix Paeoniae Alba: contained paeonol, benzoylpaeoniflorin and oxidation Radix Paeoniae have antiinflammatory action in (1) antiinflammatory, the analgesic activity Radix Paeoniae, to left agent arthritis (AA), foot swelling, acetic acid twisting reaction, shout and hot plate has obvious inhibitory action: can significantly suppress the acetic acid twisting reaction.So significant analgesia role is arranged.(2) immunity of Immune Effects Radix Paeoniae Alba decoct pair cell and humoral immunization are had potentiation, Radix Paeoniae Alba total glucosides has antiinflammatory and function dependent immunity regulating action; Make the ability of low thymocyte cell mitogen reaction and splenocyte recover normal.Also has dual regulation.(3) resisting pathogenic microbes effect Radix Paeoniae Alba antibacterial action is strong, and staphylococcus aureus, Hemolytic streptococcus, Streptococcus viridans etc. are had in various degree inhibitory action.In the Radix Paeoniae 1,2,3,4,6-five galloyl glucoses have antitoxin activity.(4) central inhibitory action can suppress spontaneous activity, strengthens the syngignoscism of ciclobarbital soluble and the hypnosis time of prolongation pentobarbital sodium, causes the lax of sleep and muscle, also has sedation simultaneously.(5) the resisting oxygen lack Radix Paeoniae Alba total glucosides can prolong the normobaric hypoxia time-to-live, reduce pressure the anoxia time-to-live, can reduce the anoxybiotic mortality rate of potassium cyanide poisoning.Can prolong panting the time behind the disconnected cranium, improve brain electrical acti, reduce brain calcium, sodium, water content.(6) the effect Radix Paeoniae Alba extract that protects the liver can be alleviated the T-2 toxin poisoning, external aflatoxin is had Degradation.(7) antimutagenic and antitumor action Radix Paeoniae Alba extract can disturb the enzymatic activity of S9 mixed liquor, and suppress the mutagenesis of benzopyrene.Wherein gallic acid and five galloyl Fructus Vitis viniferae ball sugar can make the metabolite inactivation of benzopyrene, and five galloyl Fructus Vitis viniferae ball sugar can suppress the enzymatic activity of S9 mixed liquor.Radix Paeoniae Alba total glucosides can strengthen cancer cubital lymph nodes lymphocyte enzymatic activity, may be one of its performance immunoregulation effect mechanism.(8) other act on black Chinese herbaceous peony compatibility and can strengthen the especially antiinflammatory action of Radix Aconiti of various single medicinal materials, reduce the content of capillary permeability and PGE2 in the inflammatory process and reduce the toxicity of string crow; Blood plasma and hepatic tissue LPO due to the minimizing Radix Aconiti are excessive, suppress to remove free radical.Blood drug level meets two-compartment model, but is difficult for passing through blood brain barrier.
Rhizoma Polygonati Odorati: (1) blood sugar lowering, effect for reducing blood fat blood sugar lowering, the beta Cell of islet excreting insulin is unaffected, and body carbohydrate metabolism rate improves.(2) antitumor, antimutagenic effect suppress human T lymphocyte's leukemia cell line CEM propagation, promote the expression of CEM surface molecular HLA-1 molecule, CD2 and CD3, improve the differentiation degree of CEM.The rising of the bone marrow micronuclear rates that the inhibition cyclophosphamide causes.(3) can make hemolysin amount, macrophage phagocytic function and the spleen lymphocyte proliferation ability of burn return to normal level to Immune Effects.(4) other effects improve the activity of tryrosinase.
Fructus Alpiniae Oxyphyllae: (1) has inhibitory action to neural effect Fructus Alpiniae Oxyphyllae to maincenter.(2) analgesic activity Fructus Alpiniae Oxyphyllae ketone first has good analgesic activity.(3) effect has antidiarrheal, suppresses to be damage, antiulcer function to gastrointestinal system.(4) antitumaous effect suppresses skin carcinoma deterioration, antagonism tumor.(5) delaying senility function all has antioxidant activity to the Adeps Sus domestica lipid.(6) antianaphylaxis can suppress the models of passive skin irritability reaction.Administration shows different activity to this medicine according to different approaches.
Herba Taxilli: (1) has the diastole effect to the effect of cardiovascular system to the heart coronaries blood vessel, coronary blood flow increasing, and can resist the effect that pituitrin shrinks arteria coronaria, decreased heart rate is the enhanced effect in back that suppresses earlier to cardiac contractile force.Wherein Herba Taxilli Zhong De avicularin (avicularin) composition has hypotensive effect in various degree, and has the effect of tachyphylaxis (2) blood fat reducing that the effect of cholesterol reducing and triacylglycerol is arranged.(3) diuresis does with avicularin (avicularin) diuresis is arranged.(4) anti-microbial effect has inhibitory action to Bacillus typhi, staphylococcus, poliovirus and other enterovirus; Blocking-up, propagation inhibition are directly killed, infected to Herba Taxilli ethyl acetate part to flavonoids such as (artcanoflavon) of the arteanoflavone in the Coxsackie B virus Herba Artemisiae Anomalae and total alkaloids (CVB3).
Radix Angelicae Sinensis: (1) 1. strengthens the erythrocyte aggregation that the influence of hemorheology can suppress due to macromolecule right rotary glycoside and the dexran500 bridging the effect of blood and hemopoietic system, inhibition is by the inductive red cell deformability cell change of calcium ion carrier A 23187, the hemolytic time dilation that erythrocyte is taken place in hypotonic medium.Ferulic acid can suppress various derivant induced platelets and assemble and release reaction, and its mechanism may suppress the TXA2 synthase activity with the sodium ferulate selectivity, reduces TXA2 content, and physiological levels such as increased platelets counts level are relevant.2. to the influence of hemopoietic system: Radix Angelicae Sinensis polysaccharide can make leukocyte and reticulocyte increase, and erythrocyte, hemoglobin, leukocyte and femur nucleated cell number are recovered to have remarkable facilitation.Proliferation and differentiation to grain monosystem hemopoietic progenitor cell and polytropism hemopoietic progenitor cell has remarkable facilitation; The level and the marrow stromal cell expression of GM-CSF level of expressing proteins such as marrow stromal cell, vascular endothelial cell, mononuclear cell all obviously improve after Radix Angelicae Sinensis polysaccharide is induced.(2) 1. the influence of cerebullar and cardiac system is influenced Radix Angelicae Sinensis extracting solution to ventricular muscle cell film sodium channel current and Calcium Current tool concentration dependent retardation to heart cell; Certainly the frequency of fighting that can suppress right atrium, the contractility of reduction left atrium prolongs FRP; Reduce action potential amplitude, shorten the multipole time-histories.2. the coronary dilating arteries and veins reduces significantly coronary artery dilating of myocardial oxygen consumption and function of resisting myocardial ischemia eumenol, and blood flow increasing can reduce acute anoxia oxygen consumption, keto consumpting speed and enhancing to anoxybiotic toleration.The acute myocardial ischemia and the acute myocardial infarction of energy antagonism pituitrin and caused by ligature increase cardiac muscle picked-up and arteria coronaria flow, reduce the myocardial contraction amplitude.The myocardial ischemia myocardial infarction area is significantly dwindled, impel protein kinase to transfer to cell membrane from nucleus, the activator protein enzyme suppresses myocardial ischemia.But 3. antiarrhythmic effect sodium ferulate antagonism chloroform, epinephrine, aconitine, the Ouabain arrhythmia of bringing out, and ventricular muscles irregularity of pulse due to the cardiac glycoside.This mechanism may be slow down conduction, prolong effective refractory period, eliminate and turn back, prolong plateau, suppress ectopic rhythm point and raising causes polyergic results such as the threshold that quivers.4. to the protective effect of cerebral ischemia.Can accelerate the blood circulation of cerebral tissue, improve neuronic metabolism, the middle cerebral artery bolt that the takes effect cerebral infarction area of trembling with fear, nerve growth and reparation associated protein behind the promotion cerebral ischemia, promote nerve cell adhesion molecule and the expression that promotes microtubule-associated protein, reduce the generation of natural death of cerebral cells, the natural death of cerebral cells that also can pass through double blanking bar of expression of promotion bcl-2 produces inhibitory action.(3) to blood vessel function 1. to the influencing the Radix Angelicae Sinensis decoct and can make vasodilation of peripheral blood vessel, blood pressure and blood flow, arterial pressure descends, arteria coronaria, cerebral arteries and femoral artery resistance descend, blood flow increases.2. suppress vascular smooth muscle cell (VSMC) propagation and can suppress aorta VSMC propagation, may with its increase SOD activity, rising PGI2, cAMP level reduce the lipid peroxy product, and it is relevant to suppress the expression of proliferating cell nuclear antigen among the VSMC.Slow down vascellum endometrial hyperplasia by suppressing the conversion of VSMC phenotype, point out its potential therapeutical effect atherosclerosis (AS) and percutaneous coronary endoluminal vascular plasty (PTCA) back restenosis to the VSMC inhibition of proliferation.3. the effect to vascular endothelial cell can promote human umbilical vein endothelial cell propagation and DNA to synthesize, and can make the unusual distribution of the iuntercellular viscoelastic element-1 (ICAM-1) that makes EVC304 under the shearing force effect and expression be tending towards normal.Can alleviate the EVC304 Ultrastructural damage of hyperlipemia due to clear effectively; And the expression of TGF-B1 is obviously increased, the expression of bFGF reduces.4. fall that blood refers to and the effect of arteriosclerosis can reduce hyperlipemia triacylglycerol level, improve hemorheology index, the rising of the reduction of antagonism aorta nitric oxide level and endothelin level (ET) level has study of anti-atherogenic effect.Can cause the rising that endotheliocyte secretion nitric oxide descends and ICAM-1 expresses by the antagonism OxLDL ELISA.(4) to immune influence 1. to the effect of the influence of specific immune function alcohol hypostasis ConA/LPS performance alone or synergistically promotion spleen and thymus T, bone-marrow-derived lymphocyte propagation, can also resist the inhibitory action of andrographolide (HP) to inductive spleen of ConA and thymus T lymphproliferation response.Can strengthen the function of cytotoxic T cell, the quantity of the hepatic tissue internal specific antibody of the schistosoma japonicum infection that can significantly raise.2. the influence to non-specific immunity can strengthen phagocytic activity, improves NO content, improves the defense function of peritoneal cavity, reduces the incidence rate of peritonitis.3. the obvious inside and outside spleen lymphocyte proliferation of the effect that induces of the pair cell factor, external evoked splenocyte secreted strengthens the activity of its secretions.(5) 1. the influence to reproductive system has excitation to the influence in uterus to the uterus, and uterine contraction is strengthened; H1 is receptor related on itself and the excited uterus muscle.But 2. suppress prostatic hyperplasia effect antagonism exogenous androgen aligns buck to the male and endogenous hormone of castration prostate effect of gain.3. the antigonadotropic effect can suppress hypophysis secretion lutropin, prolactin antagonist and the release of promoting sexual gland hormone zest hormone, thereby causes the female individuals miscarriage, and the testosterone of male discharges minimizing.Ferulic acid causes that serum follicle stimulating hormone level raises and the reduction of hypophysis follicle stimulating hormone (FSH) level, has the hypophysis of promotion to discharge the FSH effect.(6) to 1. liver protection effect of the effect of digestive system: can significantly reduce collagen content, alleviate hepatic fibrosis: can reduce Serum ALT and Gu Guang peptide S-and walk around and move enzymatic activity, increase glutathione reductase activity in the hepatocyte, ESA reduces mda content in the liver cytoplasm simultaneously, and ESA still can obviously suppress the increase of index and spleen index.2. choleretic effect: choleresis is had obvious facilitation, and increase the excretion of solids and cholic acid in the bile.3. suppress bowel movement: diarrhoea that intestinal segment shrinks, Oleum Ricini causes and gastrointestinal propelling that Ach is caused have inhibitory action.(7) protective effect to injury of kidney can alleviate the degree of injury that simple renal ischaemia pours into (IR) again, can adjust acute hemorrhage necrotizing pancreatitis (AHNP), TXA2, PGI2 ratio, corrects the effect that has renal function protecting unusually of hemorheology.(8) can significantly alleviate bleomycin to the protective effect of injury of lung and cause acute lung injury alveolar degree of inflammation, reduce the secretion of pneumonia medium, suppress the generation of malonaldehyde.Also reduce bleomycin and cause pulmonary fibrosis lung coefficient, alleviate alveolitis and pulmonary fibrosis, suppress fibronectin and increase, reduce MDA generation in the lung, delay the fibrosis process.(9) antioxidation, removing free radical and delaying senility function can be removed the O2-of hypoxanthine-xanthine oxidase system generation and the OH that the Fenton reaction generates, and can suppress the inductive liver lipid peroxidation effect of oxygen-derived free radicals generation systems.Can obviously improve cerebral cortex SOD, Ca2+-ATP enzymatic activity, reduce NO, Ca2+ content and NOS activity, the anti-ageing grandmother's effect of high dose is more satisfactory.Can make the active obviously increase of climacteric blood SOD, can remove oxygen-derived free radicals, the reaction of anti peroxidation of lipid thing is to the ponderable protective effect of climacteric cardiovascular system.(10) radiation resistance can make the radiation damage chromosome aberrations rate obviously descend; can significantly protect the reproductive function after the Co-r x radiation x damages; DNA and rna content in follicular cell and the oocyte are raise, and ovarian structure and function are protected, and can also significantly improve hepatic tissue SOD activity.The preventative Radix Angelicae Sinensis polysaccharide that gives can significantly promote raying bone marrow and spleen hematopoietic function recovery, prevents the thymus secondary atrophy, improves the irradiation survival rate, significantly promotes granuloid committed precursor cell to generate the recovery of unit and pluripotential hemopoietic stem cell formation unit.(11) antitumor action AP can delay ascites and produce ascitic type tumor EAC and ascitic type leukemia, prolongs the time-to-live, and the antitumor that can strengthen cyclophosphamide causes fruit.(12) anti-inflammatory and antalgic and anti-damaging action all have significant inhibitory effect to the acute and chronic inflammation that multiple proinflammatory agent causes, its antiinflammatory action still exists behind the excision bilateral adrenal gland; And can reduce the burst size that inflammation is organized PGE2, reduce the complement bypass hemolytic activity.(13) but other effect significant prolongation high pressure cause the incubation period of fainting from fear, can reverse the abnormal change of aminoacid acids neurotransmitter in the brain.Can alleviate the degree of injury of sciatic nerve, can accelerate the aixs cylinder germination process and promote reinnervation, have the effect of the neuranagenesis of promotion, also can obviously reduce fibroblast quantity and collagen content in the scar tissue, alleviate the cicatrix fibrosis.
Concha Ostreae: (1) enhance immunity effect Concha Ostreae hot water extract can make the animal spleen antibody produced cell count showed increased, can significantly suppress the nitric oxide production release of peritoneal macrophage, the peritoneal macrophage function there is remarkable influence, and can improves periphery blood T lymphocyte conversion ratio, prolongation hypoxia endurance time.(2) sedation clothes Concha Ostreae suspension has the tendency that prolongs hexobarbital sleeping time.(3) the suspension supernatant of local anesthesia effect Concha Ostreae water extract has tangible local anesthesia effect.(4) anti-experimental character gastric ulcer effect Concha Ostreae decoct has the excellent prevention effect to the gastric ulcer due to the hydrochloric acid, the effect that has antiulcer to form.(5) study of anti-atherogenic effect Concha Ostreae extract degree that aorta, coronary endometrium atheromatous plaque are formed has obviously and alleviates.
Flos Caryophylli: (1) increased gastric acid output and peptic activity of stomach.Flos Caryophylli ether extract and water extract reduce acetic acid and improve capillary permeability, suppress the swollen and pedal swelling of ear, and β-Flos Caryophylli alkene has the topical pain relief effect in the conjunctival reflex body He outside horizontal film half spacer.(2) Flos Caryophylli extract suppresses the helicobacter pylorus bacteria growing, the Flos Caryophylli extract antibacterial mechanisms may be prosperous and aminoglycoside Profilin matter synthetic competitively, eugenol is external to have inhibitory or killing effect to various skin tinea bacterium, the Human Cytomegloviru (HCMV) of the dirty fibrocyte inoculation of a large amount of direct deactivation people of Flos Caryophylli decoct embryos. and decoct also suppresses the propagation of HCMV.Caryophyllin suppresses the growth of Vero cell herpes simplex virus-1 (HSV-1), (HSV-2) etc.(3) water extract suppresses leukemia virus reverse transcriptase, can suppress virocyte and merge.(4) eugenol has the discharge activities of looking proparea-ask down thalamus front portion (PO/AH) heat-sensitive neuron and increases effect frequently. cold-sensitive neuron there is bathochromic effect.(5) eugenol and acetyleugenol reversibility suppress arachidonic acid, epinephrine and collagen-induced platelet aggregation, effect is stronger than aspirin, water extract can prolong dehisces movement time potassium cyanide poisoning time-to-live and normal pressure airtight anoxia time-to-live.(6) Flos Caryophylli first ethanol extract suppresses the chemical compound cold salmonella sudden change of causing injury, and β-Flos Caryophylli alkene etc. can induce liver and small intestinal to separate toxenzyme glutathion-S transferring enzyme, and Flos Caryophylli water extract lumbar injection presses down.
Radix Et Rhizoma Rhei: 1. the effect of pair digestive system (1) catharsis Radix Et Rhizoma Rhei decoct has tangible discharge function, and is strong with the actuating quantity of dianthrone sennoside.Sennoside decomposes or is converted into sannidin through liver through intestinal bacteria, can stimulate large intestine part or submucosal nervous plexus, the tremulous pulse wriggling is strengthened and diarrhea inducing produces the effect of volume diarrhea inducing simultaneously.(2) choleretic effect can make bile secretion increase.(3) the hepatoprotective effect Radix Et Rhizoma Rhei has the obvious suppression effect to hepatitis B antigen (HBsAg).Emodin can reduce liver fibrillation Serum hyaluronic acid, reduces CCl4 and the inductive hepatic injury of D-galactosamine, the protective effect of performance liver.(4) anti-gastric duodenal ulcer can treat and prevent stress gastric ulcer hemorrhage.Can also improve the content of coat of the stomach PGE2 (PGE2), prevent the damaging action of ethanol gastric mucosa.Emodin, aloe-emodin, chrysophanol and chrysophanic acid all have stronger inhibitory action to helicobacter pylori.(5) the effect Radix Et Rhizoma Rhei of intestinal tube smooth muscle there is tangible excitation to the electrical activity of colon.2. the propagation that can suppress film smooth muscle cell (SMC) in the arterial wall to the effect emodin of cardiovascular system suppresses the proteic expression of aortic smooth muscle cell proliferation cell nuclear antigen (PGNA), suppresses cell and transforms to the S phase from the Go phase.3. can make blood flow rate slack-off to the microcirculatory Radix Et Rhizoma Rhei that influences, erythrocyte aggregation, the local blood viscosity raises and local vascular is not expanded.Blood alkene occurs and release effect, sennoside and rhubarb polyoses composition can anticoagulant and minimizing thrombosiss.4. the effect (1) to urinary system suppresses the fibroblastic division growth emodin of people's kidney by promoting apoptosis, suppress the DNA synzyme and delay cell cycle to suppress kidney fibroblast propagation, can alleviate lupus nephritis (LN) kidney region fibrosis pathological changes, improve the prognosis of LN.(2) suppress the growth that messangial cell propagation emodin can suppress mesangial cell, suppress mesangial cell and enter the S phase from the G1 phase, improve the accumulation of productive nephritis film territorial matrix.The kidney hypertrophy that suppresses diabetes.(3) with matter Na+, the K+-ATP enzyme has stronger competitive inhibition to kidney for diuresis emodin, chrysophanic acid and aloe-emodin.(4) effect to blood urea nitrogen can obviously reduce chronic renal insufficiency model blood urea nitrogen and creatinine amount.Can also reduce acute poisoning nephritis model blood urea nitrogen.5. to the has a broad antifungal spectrum of effect (1) the antibacterium Radix Et Rhizoma Rhei of pathogenic microorganism, wherein the most responsive with staphylococcus, gonorrhea diplococcus.Antibacterial effective ingredient is the strongest with chrysophanic acid, emodin and aloe-emodin antibacterial action.(2) to being permitted blue achorion and Mongolian mutation, Trichophyton concentricunm etc. all have higher inhibitory action external for antifungal Radix Et Rhizoma Rhei decoct and water, alcohol, ether extract.(3) the antiviral Radix Et Rhizoma Rhei has stronger inhibitory action to influenza virus, and its derivant is also inhibited to human cytomegalic inclusion disease virus.6. antitumor action has inhibitory action to melanoma, ehrlich carcinoma, breast carcinoma.Emodin can strengthen cancer therapy drug 5-fluorouracil, mitomycin and the helium methopterin cytotoxicity to people's hepatocarcinoma BEL-7402, and the nucleoside excision that can strengthen DNA damage is repaired, and also optionally suppresses the activity of casein kinase i I.7. antiinflammatory action (1) suppresses the zoopery inflammation and can suppress auricular concha acute exudative inflammation and acute pleurisy, and the abdominal cavity capillary permeability is increased also inhibitory action, and acute inflammation is had tangible antagonism.(2) to the biosynthesis that emodin can suppress leukotriene B4 (LTB4) that influences of pro-inflammatory cytokine, energy activated mononuclear emiocytosis tumor necrosis factor-a (TNF-a) and interleukin-11,6,8 (1L-1, IL-6, IL-8), secretion be can also suppress simultaneously, phytohaemagglutinin (PHA) activated mononuclear emiocytosis IL-2 and interferon-r (1NF-r) also can be coordinated by the inductive above-mentioned factor of endogenous toxin.8. its chrysophanol of anastalsis, physcione, a-catechin and gallic acid can shorten hemorrhage and clotting time etc.Reduce the permeability of blood vessel, improve fragility, excited gastrointestinal local vascular, suppress pepsic activity, significantly increase fibrinogen activity.9. the effect for reducing fat rhababerone can obviously reduce serum total cholesterol to hypercholesterolemia.10. removing free radical effect Radix Et Rhizoma Rhei and can remove O2, H2O2 and other active oxygen, suppress lipid peroxidation, is a kind of antioxidant that causes that has.
Radix Sophorae Tonkinensis: 1. the contained multiple alkaloid of Radix Sophorae Tonkinensis is its antitumor effective ingredient, and wherein oxymatrine (matrine) has selective killing effect to the tumor hypoxia cell.2. the Radix Sophorae Tonkinensis total alkali has hypotensive effect, can also significantly increase the isolated heart coronary flow.Suppress phagocytosis of macrophages, reduce the level that the specificity Flos Rosae Rugosae forms cell number and serotonin, make the cell transformation of body endolymph, and share with cyclophosphamide and can produce coordinate repression from decline.3. can suppress spontaneous activity, the excitation of antagonism amfetamine can make body temperature descend, and is inhibited to the central nervous system; May have excitation to low-level center.4. Radix Sophorae Tonkinensis ear ketone has stronger anti-gastric-ulcer and suppresses the gastric secretion effect.5. escherichia coli, staphylococcus aureus, Staphylococcus albus, alpha streptococcus, group B streptococcus all there is obvious bacteriostasis.
The Radix Stemonae: 1. the resisting pathogenic microbes effect has antibacterial action to staphylococcus aureus, Staphylococcus albus, beta hemolytic streptococcus, anthrax bacillus, pneumobacillus, dysentery bacterium, Bacillus proteus, bacillus pestis, escherichia coli, Pseudomonas aeruginosa, Bacillus typhi, Salmonella paratyphi and Bacillus tuberculosis, simultaneously can suppress escherichia coli, meningococcus, Pseudomonas aeruginosa and various skin fungus, can also life-saving.2. the (-)-Stemoninine of parasiticide effect Radix Stemonae alkaloid components such as (stemonine) can make pinworm death, makes cestode the contractility activity occur, the activity of paralysis ileum; TS can also the antagonism physostigmine and strychnine to the influence of ascarid, cestode and ileum.3. the different (-)-Stemoninine alkaloid components such as (isostemonidine) that kills in the insecticide effect Radix Stemonae has killing action to body louse, pubic louse, and can make nit be difficult to hatching; Fly larvae, Cimex bedbug, Citrus aphid, cigarette snout moth's larva, cutworm etc. there is toxic action.Antitussive, eliminate the phlegm, excitement that the former Radix Stemonae alkaloid (protostemonine) in the antiasthmatic effect Radix Stemonae can reduce the animal breath maincenter, suppress coughre flex; Alkaloids extract has relexation to the tracheal smooth muscle spasm due to the histamine, mechanicalness is drawn coughed antitussive effect.5. other effect radix stemonae tuberosaes (tuberstemonine) (TS) have the excitement that weak maincenter, autonomic activities, nicotinic acid spasm, glutamic acid causes inhibitory action are arranged, and prolong the length of one's sleep; Writhing response there is analgesic activity, also can plays the effect of blocker.
Rhizoma Paridis: 1. antibacterial action is antibiotic has inhibitory action to staphylococcus aureus, Hemolytic streptococcus, meningococcus, dysentery bacterium, Bacillus typhi, Salmonella paratyphi, escherichia coli, Pseudomonas aeruginosa, bacterium sonnei, clayey serratia marcecens, escherichia coli, sensitivity and drug resistance staphylococcus aureus; Also has the effect of stronger anti-Candida albicans.2. antitumor action is to ehrlich carcinoma (EAC) tumor strain and liver substance type oncocyte, and it is synthetic to suppress tumor and spleen DNA and RNA.3. suppress fertilization 4. anastalsises diosgenin-3-O β-D-pyranglucoside and be paris polyphylla saponin (polyphyllin) and wait and to shorten clotting time and carry inside and outside blood plasma recalcification time, tell and lead the aortic article contraction.5. other effects have obvious flush end effect to asthma, and the cough that sulfur dioxide is brought out has tangible antitussive action, but does not have phlegm-dispelling functions; Little Rhizoma Paridis and colloid Rhizoma Paridis powder all can make to shrink to unpregnancy or pregnant uterus to be strengthened, and dosage increases, and it is the strongest that tension force also obviously increases little Rhizoma Paridis effect, and big Rhizoma Paridis takes second place, the colloid Rhizoma Paridis a little less than; In addition, (diosgenin-3-O-β-D-glucopyranoside) is the formation of paris polyphylla saponin (polyphyllin) Acute Morphine analgesia capable of blocking tolerance to diosgenin-3-O β-D pyranglucoside.
Herba Scutellariae Barbatae: 1. antitumaous effect has inhibitory action to capable leukemia hemocyte of acute granulocyte and intraepithelial neoplasia cells abnormality proliferation; Reduce the proliferating cell nuclear antigen positive rate, can prevent diethylnitrosamine to bring out hepatocarcinoma, delay the formation of hepatocarcinoma, reduce the onset of liver cancer rate.2. antimutagenic effect has the effect of anti-hereditary material damage, protects lymphocytic DNA.3. immunoregulation effect can obviously improve the percentage rate of esterase positive cell in the peripheral blood lymphocyte, promotes delayed allergy; Can suppress the gland index.4. bacteriostasis, escherichia coli unicellular to staphylococcus aureus, shigella flexneri, Bacillus typhi, Aerugo vacation have inhibitory action.5. other effects have lipoid peroxidization resistant, can remove the oxygen negative radical and improve the SOD vigor, have certain effect aspect slow down aging; Stronger antagonism smooth muscle shrinks function, phlegm-dispelling functions and refrigeration function are arranged.
Rhizoma Osmundae: 1. the effect of pair uterine smooth muscle has stronger contraction to the uterus, and frequency of uterine contraction and tensity are increased, and amplitude reduces, and can make the uterus be the contraction of tetanic property, and its effect is similar to Ergota.2. antiearly pregnancy and induced abortion effect have the antiearly pregnancy effect, to conceived abortive.3. estrogen-like effects can make uterus weight increase, and the vaginal cell keratinization has estrogen-like effects.4. resisting pathogenic microbes effect Rhizoma Osmundae decoct has in various degree inhibitory action to Bacillus typhi, escherichia coli, Pseudomonas aeruginosa, Bacillus proteus and staphylococcus aureus.Influenza virus PR8 strain, the 68-1 of the section strain of first type capital, Asia, 57-4 strain, new first 1 type are connected anti-77-2 strain and influenza virus is B-mode, third type and fourth type etc. all have obvious inhibitory action; Adenovirus III, poliomyelitis virus II type, hepatitis B virus surface antigen, Echovirus 9 types, Coxsackie virus, epidemic encephalitis B virus and herpes simplex virus etc. also there is obvious antitoxic action.5. anthelmintic action has the hepatic metastases of impelling effect to blood sucker, and its petroleum ether precipitate, acid deposit and dryocrassin can obviously impel the blood sucker hepatic metastases, have certain insecticidal action.
Herba Solani Lyrati: have antitumor action, cervical cancer cell is had obvious inhibitory action.
Radix Saposhnikoviae: 1. analgesic and cooling effect causes that to triple vaccine and typhoid fever, paratyphoid fever vaccine and tetanus toxoid purified mix preparation heating and yeast pyrogenicity animal anus temperature have cooling and refrigeration function.2. analgesia, calmness and anticonvulsant action can obviously suppress the writhing response due to the acetic acid, improve threshold of pain percentage rate.Spontaneous activity is reduced, and can obviously improve the interior sleeping number of 1min of sleep dosage under the pentobarbital sodium threshold.3. antiinflammatory action and Immune Effects had tangible antiinflammatory action to ear's inflammation, Radix Saposhnikoviae cimicifugoside and 5-O-methyl-visamminol swell to the Ovum Gallus domesticus album foot certain inhibitory action, inductive platelet aggregation of ADP and delayed reaction there are inhibitory action, can significantly improve peritoneal macrophage and engulf erythrocytic phagocytic percentage and phagocytic index.Radix Saposhnikoviae acidic polysaccharose A or C have the effect of accelerating to remove carbon granules.4. antimicrobial effect is to staphylococcus aureus, beta hemolytic streptococcus, streptococcus pneumoniae and produce HUANGQING fungus, variegated bent fungus, the false single stripping bacterium of Aerugo and staphylococcus aureus etc., and certain inhibitory action is arranged.5. antitumor action can obviously suppress the growth of solid tumor, the anti-tumor activity the when activate the phagocytic capacity in raising tumor immunity abdominal cavity and oncocyte combined inoculation.But after the silica gel blocking-up, the antitumor action of sposknikovan descends greatly.The effective ingredient panaxynol can reduce various tumor cells continent joint albumen E mRNA so that suppress G1 and change S into and suppress tumor cell proliferation.
Camphora: 1. Camphora is embrocated skin and can be made rubefacient, embrocates the refrigerant sensation that can produce similar Herba Menthae gently, firmly embrocates and then makes skin rubefaction, also has slight local anesthesia effect.Camphora has bitterness and burning sensation, and is for oral administration a small amount of, makes stomach have warm and comfort, and heavy dose then has stimulation, can cause nausea and vomit.Camphora can stimulating central nervous system system, particularly remarkable for high-level center, heavy dose can cause the epileptiform convulsion of cortex.Vitacampher has tangible heart tonifying, boosts and excited effect of breathing.
Borneolum Syntheticum: 1. couple central nervous system's effect Borneolum Syntheticum or isoborneol, synthetic borneol can significant prolongation the length of one's sleep.Obvious analgesia and sedation are arranged and promote growth and splitted effect.2. antiinflammatory action Borneolum Syntheticum or isoborneol have inhibitory action to inflammatory reaction with the Ovum Gallus domesticus album pedal swelling, and wherein the isoborneol effect is stronger.3. antibacterial action Borneolum Syntheticum or isoborneol, synthetic Borneolum Syntheticum have obvious antibacterial action to staphylococcus aureus, beta hemolytic streptococcus, Streptococcus viridans, streptococcus pneumoniae and escherichia coli.4. antifertility action is to the early stage no obvious induced labor effect of gestation, to remarkable induced labor effect is arranged in mid trimester of pregnancy and late period.5. other effect Borneolum Syntheticum or isoborneol can obviously prolong the normobaric hypoxia time-to-live, and Borneolum Syntheticum can the duodenal contraction of part antagonism.
Rhizoma Acori Graminei: the 1. effect of pair nervus centralis (1) sedation: Rhizoma Acori Graminei water decoction and the empty injection of the water decoction abdomen that deoils reduce independent activity of animals, with the pentobarbital sodium of subliminal hypnosis dosage significant synergism are arranged.(2) anticonvulsant action: its extraction volatile oil has the antiepileptic effect.(3) to the animal learning memory impairments: to the memory acquisition disturbance that eastern Liang alkalium causes, the memory that sodium nitrite is caused is consolidated memory represents bad and that ethanol causes and is lacked the effect that all has clear improvement.Its mechanism of action is the total volatile oil of Rhizoma Acori Graminei.2. suppress trachea contraction asarabacca brain (euasarone) and can suppress the tracheospasm contraction, and have tangible dose-effect relationship.3. antiarrhythmic effect elemicine (elemicin) has certain therapeutical effect to the arrhythmia of being brought out by aconitine, also has the effect of decreased heart rate.4. other act on the uterine contraction effect that a-asarone (asarone) can resist pituitrin, can kill ascarid, and are stronger to ascaris suum paralysis and lethal effect: as can also to kill ascites cells in addition.
Oletum Trogopterori: 1. the anticoagulant effect can significantly suppress by ADP, the inductive platelet aggregation of collagen, and common carotid artery-external jugular vein blood flow bypass experimental thrombosis is formed with remarkable preventive and therapeutic effect.2. to the remarkable coronary blood flow increasing of the effect of cardiovascular system and microcirculation disturbance, reduce coronary resistance, and reduce work done of left chamber and Peripheral resistance, and the myocardial nutritional flow amount is increased; Can cause microcirculation disturbance to antiadrenergic drug good improvement effect is arranged.3. the anti-stress damage can prolong swimming time and hypoxia endurance time, also can significantly improve the survival rate under cold or hot conditions.4. can improve thymus broken number, the spleen index of normal or hypoimmunity to Immune Effects, peritoneal macrophage phagocytic function, the lymphocytic conversion of T; Strengthen the mononuclear cell phagocytic function, promote the formation of hemolytic antibody.The suppression of natural killer cytoactive, and make transferring to unusually of TS function due to the ALS normal.5. gastric ulcer and gastric acid secretion effect there is the effect of the gastric ulcer due to gastric acid inhibitory secretion, protection gastric mucosa, the prevention pylorus ligation.6. antioxidation can make in the body superoxide dismutase (SOD) vigor improve and change with dosage and time, also can activate body endogenous SOD activity.7. can also reduce hematoma urea nitrogen content and aminotransferase value to a certain extent after only acting on both compatibilities with other medicine compatibilities, prove the infringement that can not increase intact animal liver, kidney behind the compatibility.Simultaneously body weight is normal, illustrate that the compatibility use do not have obvious influence to growth promoter.The people participates in the Oletum Trogopterori compatibility total white blood cells and classification, platelet count, content of hemoglobin is not made significant difference.
Also Chinese herbaceous peony: 1. antithrombotic forms and antiplatelet aggregative activity Radix Paeoniae Rubra decoct can make thrombus formation time obviously prolong, contraction in length, weight saving; Can prolong clotting time, shorten the cold breathing dyspnea with rapid and short breath time of lung bolt, Radix Paeoniae Rubra total glycosides is to produce anti thrombotic action by the influence to blood coagulation system and platelet function.2. can improve erythrocytic permeability to erythrocytic effect Radix Paeoniae Rubra, increase erythrocyte, can stablize the erythrocyte membrane structure hypotonic tensile resistance.3. arteriosclerosis effect Radix Paeoniae Rubra has tangible regressive effect to the AS focus, and aorta AS focus and coronary artery AS focus are reduced, and tangible blood fat reducing, anti peroxidation of lipid, degraded plasma fibrinogen and anti-smooth muscle cell proliferation effect are arranged.4. to the cardiovascular system interaction energy heart coronary flow and tremulous pulse coronary flow are increased, can increase the vein coronary flow, the vein Peripheral resistance is reduced; The myocardial nutritional flow amount is increased; Pulmonary hypertension there are treatment and preventive effect, lung vasodilation, lung improving blood flow, pulmonary artery pressure reduction, cardiac output increase, cardiac function are improved.5. to function of tumor the vascular endothelial cell growth factor that liver transplantation shifts in the sarcoma spleen is obviously raise, the tumor tissues microvessel density improves; Radix Paeoniae Rubra can promote the generation of tumor invasion and transfer.6. hepatoprotective effect Radix Paeoniae Rubra has obvious facilitation to hepatocellular DNA is synthetic, and liver cell regeneration and liver function recovery are had good influence.Hepatic injury due to the D-galactosamine there is obvious protective effect, survival rate is increased, obviously fall liver atrophy and alanine aminotransferase.7. other effect river Radix Paeoniae Rubra extracts have inhibitory action to beta-hydroxy-Beta-methyl 1,3-propanedicarboxylic acid coenzyme A and Ca2+ channel blocker receptor.Also the Chinese herbaceous peony total glycosides has protective effect to the neurocyte of 6 kinds of neurocyte ischemic injuries, can improve the neuron survival number; Super calcium damage has significant protective effect to adrenal pheochromocytoma tumor clone strain cell.
Ramulus Cinnamomi: 1. antibiotic, its ethanol extract of antivirus action all has certain inhibitory action to staphylococcus aureus, streptococcus pneumoniae, escherichia coli, Bacillus proteus, dysentery bacterium, Bacillus typhi, the 68-1 of the section strain of influenza virus methylene capital and Orphan virus (ECEO11) etc.2. there are analgesic, its water decoction of analgesic activity and cinnamic aldehyde can make that heating person's body temperature descends due to typhoid fever, the paratyphoid vaccine.The effect of its analgesic and cooling may with its expansion peripheral blood vessel, promote diaphoresis, heat radiation relevant.3. calm anticonvulsant action cinnamic aldehyde can make autonomic activities reduce, and strengthens the sleep effect, and can resist central excitation and prolong the death time of fainting from fear due to the strychnine and suppress audiogenic convulsion.4. antiinflammatory action has the obvious suppression effect to the foot due to the chondrus ocellatus Holmes is swollen, and arthritis is had certain preventive effect.5. the interaction energy of blood vessel, blood is removed the contraction of blood capillary, reduce plasma fibrinogen content, reduce the blood plasma viscosity, help the abundant exposure and the distortion activity of hemocyte surface charge, thereby whole blood viscosity is reduced, and can remove erythrocyte and platelet aggregation, improve the tissue blood circulation, eliminate the edema of sarcoplasmic reticulum and Schwann cell endoplasmic reticulum, make pathological tissues reverse reparation the myocardial nutrition blood flow is increased.
Cortex Cinnamomi: 1. antitumor action cinnamic aldehyde (cinnamaldehyde) can suppress the tumor due to the SV40 and infect dust interest growth of tumor that the obvious suppression effect is arranged, generation that can also induced tumor necrosin (TNF); Stimulate human red blood cell propagation, significantly the activity of enhanced CT L also can stimulate the immunoglobulin of B cell and monocytic IL-1 to breed, and can be used for the cancer diagnosis patient.2. gastrointestinal motility influenced in the Cortex cinnamomi japonici (Ramulus Cinnamomi) benzene first formula aldehyde volatile oils such as (benzaldehyde) carminative that is good for the stomach, gastrointestinal there is demulcent stimulation, Vaccinium bracteatum Thunb. wood gum phenol-3a-O-β-D-glucoside (lyoniresinol-3a-O-β-D-glucopyranoside) to cold or water logging stress gastric ulcer, multiple ulcer model, pancreatin has inhibitory action.3. antiplatelet aggregative activity cinnamic aldehyde (cinnamal dehyde) can anticoagulant, the experimental thrombosis of endotoxin induced is formed, and stagnated blood of liver, hemorrhage due to the endotoxin, the release of arachidonic acid (AA) has inhibitory action; Cinnamic acid is also had an anticoagulated blood consolidation.4. can strengthen the myocardial contraction and the heart rate of heart to the effect cinnamic aldehyde (cinnamaldehyde) of cardiovascular system, increase the secretion of catecholamine; Heart coronary flow and cerebral blood flow are increased, and the expansion peripheral blood vessel.The volatilization wet goods of the benzyl benzoate in the Cortex Cinnamomi (benzyl benzoate) all has antagonism to cardiac function and the hemodynamics change that isoproterenol causes, diastolic pressure is fully improved, coronary artery and intracranial arterial infusion are pressed corresponding increasing, and promote myocardium side Zhi Xunhuan open.5. to the influencing cinnamic aldehyde (cinnama ldehyde) and can obviously reduce non-specific immunity and production of antibodies of phagocytic function, Cortex cinnamomi japonici (Ramulus Cinnamomi) Polysaccharide A X can obviously improve the phagocytic function of reticuloendothelial system to carbon granules.6. central nervous system's influence there is inhibitory action to the motion excitement of going morphine or desoxyn to produce, significantly increases in the striatum 3,4-dihydroxyphenyl acetic acid, 4-hydroxy-3-methoxy-.alpha.-toluic acid. and 5-hydroxyindoleacetic acid.7. antiinflammatory action is to acute and chronic inflammatory reaction, swollen, the capillary permeability increase of the sufficient sole of the foot due to the carrageenin, cinnamic aldehyde (cinnamaldehyde) all has certain inhibitory action, adjuvant-induced arthritis there is preventive effect, can prevents the secondary symptom (ear's hyperemia, edema, flatulence etc.) of its whole body.8. antibacterial action Cortex cinnamomi japonici (Ramulus Cinnamomi) skin aldehyde (cinnamal dehyde) has very strong fungicidal action, especially with the strongest to the dermatophytosis effect.9. delaying senility function significantly increases activities of antioxidant enzymes and Total antioxidant capacity, reduce Radical Metabolism product content, improve the activity of tissue film's enzyme, improve the cytolipin flowability, thereby function in delaying senility is played in the integrity of protection cell membrane and the normal performance of function; Cortex Cinnamomi water extract, ethanol extraction have antioxidant activity, also can suppress the inductive external liver lipid peroxidation of FeCl2-Vc.
Radix Aconiti: 1. antiinflammatory action can suppress that capillary of skin permeability due to ear swelling due to pedal swelling due to carrageenin, Ovum Gallus domesticus album, histamine and the 5-HT, the dimethylbenzene, histamine, the 5-HT is hyperfunction, due to the Oleum Tiglii granulation capsule ooze out with hypertrophy and carrageenin due to the leukocyte of pleurorrhea in the inflammation kitchen range, assemble, reduce the total white blood cells in the transudate; For immune inflammation, can suppress skin delayed hypersensitivity due to the passive Arthus of reversibility reaction and the tuberculin.2. analgesic activity Radix Aconiti total alkali all has significant analgesia role in hot plate method, acetic acid twisting method.3. the hypoglycemic activity aconitane has the effect of the euglycemia of reduction, can strengthen the phosphofructokinase activity, and the glycogen synthetase activity is had enhancing trend, shows that the blood sugar lowering mechanism of aconitane A is the utilization of enhancing body to glucose.4. first-born product of effect Radix Aconiti and the processed product water decoction to cardiovascular system has cardiotonic, strengthens as dosage then to cause arrhythmia, causes heart eventually and suppresses.Chordotomy and neuroganglion Interruption all can prevent and eliminate arrhythmia and the hypertension that aconitine causes.Strengthen the toxic action of Ouabain in addition to cardiac muscle.5. can cause writhing response to neural effect aconitine, the local anesthesia effect is arranged, the retardation of sciatic nerve-trunk is equivalent to 31 times of cocaine.6. the antitumaous effect Aconitum carmichjaelii Debx. has inhibitory action to stomach cancer cell, and this effect strengthens with concentration, and can suppress the mitosis of gastric carcinoma cells.
Radix Aconiti Kusnezoffii: 1. the aconitine in the analgesic activity Aconitum carmichjaelii Debx. has significant analgesic activity.2. antiinflammatory action can promote sufficient sole of the foot edema extinction, can suppress ear swelling and abdominal cavity capillary permeability, and antiinflammatory action is arranged.3. to the influencing the Aconitum kusnezoffii Reichb total alkali and can strengthen the effect of epinephrine of heart, can strengthen the toxicity of Ouabain to cardiac muscle to cardiac muscle; The large artery trunks that can relax, anticoagulant and lipopolysaccharide-induced NO product and the expression of iN-OSmRNA have anti thrombotic action.Aconitum kusnezoffii Reichb total alkali antihistamine, local anesthesia effect.
Herba Ephedrae: 1. the effect Herba Ephedrae of pair cardiovascular system has adrenomimetic drug energy effects on neural system, and blood pressure and heart rate are raise, and booster reaction can produce tachyphylaxis.2. the eliminating phlegm and relieving cough effect Herba Ephedrae volatile oil of relievining asthma can prolong histamine and cause the time of breathing heavily, and antitussive effect is arranged.3. the moisture of its vola portion of diaphoresis diuresis distributes (diaphoresis) and presents the dose dependent perspiration, and oral ephedrine or left-handed methylephedrine (methylephedrine) can impel the vola diaphoresis, and the urine amount is increased.4. influence the Herba Ephedrae water extract and ethanol extraction has anti-allergic effects to lung sections to immune, suppress the effect that basophilic leukocyte relevant with the I allergic reaction type and mastocyte discharge chemical mediators such as histamine.Can alleviate auricle swelling, make atrophy of thymus gland, adjust the imbalance of CD4/CD8 in the blood, immunity is had inhibitory action.5. the vascular permeability of antiinflammatory action increases, and suppresses the formation and the edema of chick chorioallantoic membrane granulation tissue.Ephedrine can suppress Fructus Crotonis oiliness ear swelling, the foot swelling of chondrus ocellatus Holmes colloidality and the swollen and granuloma induced by implantation of cotton pellets of the formaldehyde foot sole of the foot.6. the refrigeration function Herba Ephedrae has refrigeration function and cooling effect.7. the influence to nerve and neuromuscular transmission has antifatigue effect to yellow alkali to skeletal muscle, suppresses normal person's neurotransmission.But the caused neuromuscular paralysis of the high potassium depolarization of Herba Ephedrae antagonism, contraction has of short duration excitation to diaphram.8. the angiogenesis of antitumor, antimutagenic effect system Human umbilical vein endothelial cells and B16F10 melanoma cells are invaded matrix membrane, and to benzopyrene, 1, inductive sudden changes such as 6-dinitro pyrene have inhibitory action.9. the low chronic renal failure blood urea nitrogen of other effects, creatinine, methylguanidine are corrected the high phosphorus hypocalcemia, improve renal function.Herba Ephedrae has inhibitory action to hemophilus influenza, alpha streptococcus, streptococcus pneumoniae, neisser's coccus, bacillus subtilis, escherichia coli, Candida albicans etc.And the steatolysis effect that methylepinephrine promotes and the angiogenesis of Human umbilical vein endothelial cells.Can also prolong prothrombin time, shorten the blood plasma euglobulin lysis time, reduce blood viscosity, improve its blood flow stream degeneration.The effect of the free radical of removing is arranged.
Rhizoma Alpiniae Officinarum: thrombus formation time is postponed, platelet aggregation is had obvious inhibitory action.Analgesia and antiemetic effect are arranged, choleretic effect is arranged, improve the ability of utilizing of oxygen.
Herba Asari: 1. antipyretic effect Herba Asari a-pinene volatile oil components such as (a-pimene) is very strong to cooling effect normal and heating body temperature, and analgesic activity is arranged.2. anticonvulsant action Herba Asari myrcene (myrcene) has anti-electrofit and the effect of pentetrazole convulsions, can resist electrofit fully, can prolong pentetrazole and faint from fear incubation period and death time.3. antiinflammatory action limonene (limonene) can suppress the pedal swelling that yeast, formaldehyde, carrageenin, histamine or PGE2 cause, skin is floating, ear swelling, granuloma induced by implantation of cotton pellets and plastic hoop granuloma; Can prevent the primary affection of adjuvant-induced arthritis, the Secondary cases pathological changes is also had the obvious treatment effect.4. the body endolymph cell transformation that immunosuppressive action Oleum Asari pair cell immunity, humoral immunization phytohaemagglutinin (PHA) bring out and the generation of hemolytic antibody.5. the local anesthesia effect all has obvious inhibitory action can suppress urinary protein excretion increases; And can improve the serum biochemistry index.Can block sciatic conduction of impulse, and the tool reversibility.6. the influence to cardiovascular system can make left chamber pumping function and myocardial contractility obviously improve, and can improve mean arterial pressure, left chamber contractive pressure and the arteria coronaria hole blood flow of shock animals, reduces central venous pressure; The ethyl acetate soluble fraction of Herba Asari can suppress the vasoconstriction due to the potassium chloride, and the arteriole blood flow that epinephrine is caused stops or slowing down that slight retardation function is arranged, and the caliber contraction time is had obvious retardation function.7. antibacterial action kakuol preserved material, volatilization wet goods have inhibitory action to gram positive bacteria, tubercule bacillus, bacillus subtilis and Bacillus typhi, and the Herba Asari decoct also has inhibitory action to reaching Bacillus typhi.8. other effects have the function that improves organism metabolism, and the effect of adrenergic p receptor stimulating agent sample is arranged, and the effect that strengthens lipid metabolism and rising blood glucose is arranged.
Olibanum: 1. the antiinflammatory action boswellia serrata is set (B, serrata) the effective ingredient a among the gum resin exudate salaiguggal (AESG), β-boswellic acid (a-β-boswellic acid) has antiinflammatory action, words and deeds edema due to edema due to the chondrus ocellatus Holmes and the dextran there is obvious antagonism, PARA FORMALDEHYDE PRILLS(91,95) and adjuvant experimental arthritis AESG can produce the effect of anti-joint, AESG can reduce serum glycosylhydrolase (glycohydrolases) and the glycoprotein concentration that the arthritis animal raises simultaneously, and can suppress neutrophil migration.2. pair cell and humoral immunization influences the AESG gum resin and can obviously suppress it to the generation of erythrocyte antibody (EA) and cell effect, apocyte, the neutral leukotriene B4 (leukorienesB4 in abdominal cavity, LTB4) pleura oozes out due to the formation, reduction carrageenin.3.AESG it is synthetic to reduce the liver cholesterol.4. Olibanum has significant analgesia role.
Myrrha: 1. effect for reducing blood fat Myrrha oleo-resins can reduce hypercholesterolemia, and can prevent the formation of arterial wall speckle, body weight is alleviated to some extent, blood fat reducing is arranged and the effect of reducing fat, and can suppress the synthetic platelet of bringing out of liver homogenate cholesterol with ADP, epinephrine and 5-hydroxy tryptamine.2. the effect of thyroxine sample can make its thyroxine take the photograph iodine, thyroid peroxidase, proteinase activity liver and biceps oxygen consumption increases.3. astriction is to mucosa Ouyang astriction.4. the oleoresin petroleum ether of antiinflammatory, antipyretic effect Myrrha has antiinflammatory, antipyretic effect, can obviously suppress inflammation due to carrageenin and the granuloma induced by implantation of cotton pellets, and the blood stasis swelling that the foreign trader is caused all has significant detumescence effect.5. antibacterial action is to trichophyton, Trichophyton concentricunm, and being permitted multiple pathomycetes such as blue achorion has in various degree inhibitory action.
Radix Sophorae Flavescentis: 1. the effect of pair cardiovascular system (1) all is the positive inotropic action that agent relies on to matrine contained in the action of the heart Radix Sophorae Flavescentis (matrine), sophocarpine, oxymatrine (oxymatrine), sophoridine (sophoridine), sophoramine alkaloids such as (sophoramine) to papillary muscle preparation, when excessive, the spontaneous contraction or the irritability reduction appears.The spontaneous frequency of right atrium that can significantly slow down, the heart rate that the antagonism isoproterenol brings out is accelerated; (2) antiarrhythmic effect matrine (matrine) and oxymatrine (oxymatrine) can significantly resist arrhythmia, the ventricular fibrillation that barium chloride, aconitine and chloroform-epinephrine bring out, improve aconitine and bring out the required amount of arrhythmia, also can resist the arrhythmia due to the ligation branch of coronary artery; (3) function of resisting myocardial ischemia can delay the asystole time to acute myocardial ischemia due to the pituitrin, and the electrocardiogram pathological change that myocardial ischemia is caused has some improvement; (4) influencing matrine (matrine) and can obviously resist media smooth muscle cell proliferation and the hypertrophy that Angiotensin II causes blood vessel and blood pressure, suppress the interior calcium overload of media smooth muscle cell that Angiotensin II causes, thus can anti-angiogenic middle level smooth muscle cell proliferation.Reduce blood viscosity, improve hemorheological indexes.Suppress the effect of fibrin fibrinogen degradation product and the propagation that aortic endothelial cell discharges lactic acid dehydrogenase and smooth muscle cell, reduce peritoneal macrophage secretion interleukin.2. the interaction energy to the central nervous system suppresses autonomic activities, the central excitation effect of antagonism amfetamine and caffeine, and matrine has analgesic activity, and matrine (matrine), oxymatrine (oxymatrine) have the effect that reduces normal body temperature.3. relieving asthma and anti-allergic effects.Radix Sophorae Flavescentis total alkaloids, Radix Sophorae Flavescentis crystalline alkali have tangible antagonism to asthma, and oxymatrine (oxymatrine) can alleviate the contact dermatitis reaction that dinitrochlorobenzene brings out, and suppresses the cell-mediated mast cell degranulation of homology kind; Sophocarpine can be to asthma.To immune matrine (matrine), oxymatrine (oxymatrine) and the sophocarpine republicanism sophocarpine of influencing to immunologic function, body rejection, the propagation of activating T cell, with delayed hypersensitivity and tumor cell proliferation effect inhibitory action is arranged, reduce plaque forming cells's number and antibody geometric mean titer, prolong allosome free grafting cardiac muscle survival period, illustrate that matrine has direct cytotoxicity to macrophage.5. the effect Radix Sophorae Flavescentis total alkaloids to blood system has tangible rising effect to peripheral leukocytes, and the leukopenia due to the total irradiation of X line is had therapeutical effect; Oxymatrine (oxymatrine) can prevent to divide leukopenia due to the rimocidin C (MMC) because of silk.6. antitumor action matrine (matrine) can suppress the propagation of sarcoma, ehrlich carcinoma, hepatocarcinoma, people's adenocarcinoma of stomach cell, tumor cell and endotheliocyte stick expression with adhesion factor, the transfer of ameliorate tumor can make cell aggregation in the S phase, plays induction of differentiation.Can make cyclophosphamide cause that the toxicity of leucocytes reduction obviously alleviates, promote the differentiation of inducing of human red white corpuscle system, ability of cell proliferation is obviously descended.7. anti-hepatitis and fibrosis effect matrine (matrine) can reduce serum TNF and ALT level and to the sensitivity of lethal toxicity, can discharge TNF through the pre-peritoneal macrophage that stimulates of propionibacterium acnes in vitro inhibition, with duplicating of B-mode scorching virus, can alleviate hepatic necrosis and proliferation of fibrous tissue, reduce different experiments stage serum alanine transaminase, hyaluronic acid, hepatic tissue hydroxyproline content, can suppress simultaneously the propagation of fat-storing cell and synthesizing of extracellular matrix, the effect of anti-hepatic fibrosis is described.Quiet notes matrine (matrine), blood drug level-time graph are two exponential types, meet open two-compartment model, and tissue content is followed successively by kidney, liver, lung, brain, the heart, blood behind the filling stomach matrine.
Last Poria: 1. antitumor action has remarkable inhibition effect to the aflatoxin hepatocarcinogenesis, can make the preceding focus decreased number of hepatocarcinoma, and area dwindles.But to N-butyl-N-(4-hydroxyl butyl) tumor of bladder that nitrosamine (BBN) is brought out, Rhizoma Smilacis Glabrae does not have obvious inhibitory action, and more squamous cell type tumor has taken place.2. receptor blocks the arrhythmia that sample interaction energy prevention epinephrine causes, the antagonism isoproterenol makes parallel the moving to right of amount-effect curve of isoproterenol to the positive inotropic and the positivity frequency effect of heart; Can prevent that heart rate from accelerating, the T ripple falls stomach, ventricular premature contraction and rapidity ventricular arrhythmia, and heart rate is slowed down gradually, shrinkage amplitude reduces gradually.3. the Detoxication to gossypol has the acute and subacute gossypol poisoning effect of antagonism.4. effect (1) function of resisting myocardial ischemia to cardiovascular system can bring out the acute myocardial ischemia phase at isoproterenol; be dose dependent ground protection ischemic myocardium SOD, Se-GSH-Px activity; reduce MDA content, reduce CPK and discharge, alleviate the Ultrastructural damage of ischemic myocardium.(2) the red Rhizoma Smilacis Glabrae of study of anti-atherogenic effect can significantly reduce the incidence rate of experimental atherosclerosis speckle under the situation that does not influence serum cholesterol, and the effect of anti-pulse atherosclerosis is arranged.5. the cellular immunization inhibitory action can suppress the toe disease reaction due to contact dermatitis and the sheep red blood cell (SRBC) and optionally suppress cell immune response.6. the astilbin (astilbin) in the diuresis Rhizoma Smilacis Glabrae can obviously increase the total amount of urinating, and dose-response relationship is arranged, and 1h can increase urine Na+ output after the administration, but urine K+ is discharged unobvious the change.7. analgesic activity can obviously suppress glacial acetic acid writhing response number of times, can prolong the pain response latency that hot plate causes, illustrates that astilbin (astilbin) has significant analgesia role.
Rhizoma Curcumae Longae: 1. the foot that produces of on Carrageenan such as antiinflammatory action curcumin, demethoxycurcumin is swollen inhibitory action, and it is swollen also to suppress acute foot, and its early stage antiinflammatory action is because antihistamine, and late period antiinflammatory action system because of due to the excited pituitary adrenal axis.2. hepatoprotective effect has obvious inhibitory action to Serum ALT and the AST rising that carbon tetrachloride causes.Anti-liver toxicity is arranged.3. the interaction energy to cardiovascular system increases the myocardial nutrition blood flow, and of short duration hypotensive effect is arranged, and curcumin has inhibitory action to heart.4. the effect of anticoagulant and anticoagulant can suppress the inductive platelet aggregation of hyperlipemia ADP; Curcumin can strengthen fibrinolytic and live.The platelet aggregation that collagen, epinephrine brings out can be suppressed and recalcification time can be prolonged.5. the effect for reducing blood fat curcumin can reduce bait hyperlipemia serum TC and TG concentration, increases HDL-C content, significantly reduces LPO content.Curcumin may be by promoting liver and the adrenal gland metabolism to low density lipoprotein, LDL and lipoprotein a, increasing gallbladder drains low density lipoprotein, LDL, suppress the picked-up of spleen to low density lipoprotein, LDL, the content of low density lipoprotein, LDL and lipoprotein a in the blood is reduced, thereby have prize blood fat and study of anti-atherogenic effect.6. antioxidation can be to the skyborne oxidation Wheat Protein of linoleic acid, and phenolic hydroxyl group is to the unusual weight of its antioxidant activity, and the methoxyl group adjacent with phenolic hydroxyl group is also relevant with its antioxidant activity; Early, middle and late phase gestation is had obvious termination, also can obviously suppress the growth of the traumatic uterine decidua tumor of pseudo-fetus, the mechanism of its anti-early pregnancy may be because due to gestation and the palace contraction.7. antitumor action is inhibited to the melanoma cell lung transfer of high-metastasis tendency, and curcumin has the cytotoxic effect that is better than gallic acid to leukaemia and cancer cell of oral cavity.Curcumin is all induced the effect of dying of transferring to multiple cancerous cell such as the embryo fibroblast of oncogene transfection and meat cell, colon cancer cell, kidney cancer cell, hepatoma carcinoma cell, has phototoxic effect, this phototoxic effect need have under the aerobic conditions and could produce, and this phototoxicity and oxygen-derived free radicals to intensify the generation of central carbon atom of attitude relevant; Can reduce under the illumination condition and induce the needed drug level of people's adenocarcinoma of stomach cell MGC-803 apoptosis, i.e. illumination that the effect that promotes the curcumin cell death inducing is arranged.
Rhizoma Pinelliae: 1. town's Tuhe emetic action Rhizoma Pinelliae Preparata has the town to tell effect, and Rhizoma Pinelliae has emetic action.2. rare alcohol of the antitussive and the phlegm-dispelling functions 3. antitumaous effect Rhizoma Pinelliaes can suppress hepatocarcinoma HCA, sarcoma, cervix uteri tumor, and Rhizoma Pinelliae polysaccharide component has polymorphonuclear leukocyte activation and antitumor action simultaneously; Each processed product total alkaloids of the Rhizoma Pinelliae all has inhibitory action to the growth of chronic myelogenous leukemia cell, and the strongest with the effect of the anti-K562 growth of tumour cell of the vitriol Rhizoma Pinelliae.4. antifertility and antiearly pregnancy effect pinellin can suppress the secretion of corpus luteum progesterone, the plasma progesterone level is obviously descended, and the endometrium attenuation fades away decidua reaction, the embryo loses the decidua support and miscarries, and tangible antiearly pregnancy effect and anti-blastocyst implantation effect are arranged.5. anti-arrhythmia interaction energy rapidly disappears premature beat, makes adrenal gland's disposition tachycardia transfer sinus rhythm to.6. the anti-experimental character gastric ulcer is to indomethacin (indometacin) type; pylorus connects the bundle type; chronic acetic acid type gastric ulcer has apparent prevention or therapeutical effect; the water logging stress ulcer also there is inhibitory action; and apparent minimizing gastric juice amount arranged; reduce free acid and total acidacidity, suppress the effect of pepsin activity, acute injury is had protection and promotes the mucosa repair.7. other effects have inhibitory action to development of pneumosilicosis, and lung is lower in weight or weight in wet base, and lung collagen protein amount reduces, and pathological change is lighter; Administering effect is best, and morbidity back administration also has certain curative effect, and the content of the silicon dioxide in the lung tissue does not have significant change.Pinellin and erythrocyte have the peripheral blood lymphocyte of promotion transformation, the Rhizoma Pinelliae also has significant effect for reducing blood fat, stop or delay the formation of hyperlipidemia, hyperlipemia is had certain therapeutical effect, the polysaccharide that extracts from the Rhizoma Pinelliae has stronger reticuloendothelial system and activates active.
Pheretima: 1. the influence of pair blood coagulation and anticoagulation system can make fibrin descend, and thrombin time, prothrombin time and KPTT prolong, and can make II, the degraded of the VIII factor, plays stronger anticoagulant effect; Contained fibrinolysin and the former being preparation of plasminogen in the Lumbricus has good appearance bolt effect, and blood plasma tissue plasminogen activator (t-PA) vigor is increased, and platelet aggregation, whole blood viscosity and blood plasma viscosity and erythrocyte rigidity index reduce.In the intravital fibrinolytic bolt of the Pheretima composition, plasminogen activator (ePA) can cut basic amino acid, little medium-sized aminoacid and the c-terminus of Met, also plasminogen can be cut into fibrinolysin.Fibrinolysin is direct fibrinolytic effect with the fibrin hydrolysis.Lumbrukinase activates plasminogen for fibrinolysin, then is indirect action; Pheretima not only can be dissolved fresh thrombus, and contained collagenase can be a collagen protein with old property thromboembolism also, can significantly improve erythrocyte deformability to reduce blood viscosity.2. arrhythmia, barium chloride or the Ouabain that influence (1) antiarrhythmic effect of cardiovascular system is brought out the aconitine arrhythmia of bringing out all has obvious antagonism.(2) hypotensive effect has hypotensive effect to kidney type hypertension, can show inhibition Angiotensin-Converting activity.3. can improve the level of macrophage and splenocyte secretion nitrogen oxide (NO) to (AL) of Immune Effects Pheretima, and the antagonism Decalix in and the excretory inhibitory action of splenocyte.4. antitumaous effect has obvious inhibitory action to solid tumor and sarcoma.5. antiasthmatic effect can make egg protein and inhale the allergic asthma that people's histamine causes and obviously prolong incubation period, and the isolated tracheal that is caused by histamine is shunk obvious inhibitory action; Expansible bronchus, the bronchoconstriction that antihistamine and pilocarpine are caused.Antiinflammatory, analgesia and promote the wound healing effect to show to suppress that auricle swelling, carrageenin cause that pedal swelling, acetic acid cause that the abdominal cavity capillary permeability increases, Ovum Gallus domesticus album is to foot swelling, prolongs hot plate method pain reaction incubation period; Can improve the healing rate of epidermis, muscle, promote the growth of fibroblast, blood capillary, collagen fiber and DNA in the granulation tissue; Increase the quantity of actin in the muscular tissue, help the contraction of wound.7. refrigeration function all has good refrigeration function to heating due to endotoxin and the warm stimulation.8. to sperm and organize spermatiation that sperm is had the effect of killing fast, can make succinic acid, hyaluronic acid can make sperm braking, coagulation rapidly, and its structure is damaged.
The Radix Aucklandiae: 1. pair gastrointestinal effect can make enterokinesia amplitude and flesh intestinal tension force obviously strengthen, and flesh enterospasm is had antagonism; Dihydrocostulactone (dihydrocostuslactone) can suppress the intestine and small intestine cloud top, reduces tonicity and rhythmicity and shrinks; Dehydrocostuslactone (dehydrocostuslactone) can promote the secretion of somatostatin, and has choleretic effect.2. to the effect that constuslactone (costuslactone), costen (costene) etc. have the rising blood pressure that influences of blood pressure, lactone volatile oil, total lactone, constuslactone (costuslactone), dihydrocostulactone (dihydrocostuslactone), dehydrocostuslactone (dehydrocostuslactone) and 12 methoxyl groups, two constuslactones have hypotensive effect simultaneously.Antiinflammatory, analgesic activity can suppress that writhing response, ear are swollen, the raising of foot swelling and abdominal cavity capillary permeability, antiinflammatory action is arranged, and can significantly reduce alkali phosphatase, acid phosphatase, r-glutamyl transpeptidase and the protein level that raises and reduce.4. the Sesquiterpene in other effect Radix Aucklandiae can suppress nitric oxide production synthetic, tumor necrosis factor; Costunolide (costunolidc) dehydrocostuslactone (dehydrocostuslactone) can suppress the expression of the killing activity of cytotoxic T lymphocyte and people's the hepatocellular hepatitis B virus surface antigen of Hep3B (HBsAg) respectively, HbsAg's is synthetic, and the mRNA that suppresses the HbsAg of HepA2 cell.
Fructus Citri: contained Hesperidin has the effect of Citrin sample, can reduce the permeability of blood capillary, prevents that capillary vessel is hemorrhage, energy antagonism histamine, the vascular permeability that LYSO-PHOSPHATIDYLCHOLINE LYSOPC causes increases, energy fortifying fibre protein dissolution, antithrombotic forms, and choleretic effect is arranged.
Radix Aconiti Lateralis Preparata: the 1. effect of pair cardiovascular system (1) cardiotonic: Radix Aconiti Lateralis Preparata has racemization demethyl coclaurine, coryneine chloride, Salsolinol etc. to have cardiotonic.Serum there is the effect that strengthens myocardial contraction and accelerate myocardial contraction speed.(2) to the influence of cardiac rhythm: Radix Aconiti Lateralis Preparata quivers to chamber due to the chloroform preventive effect, can reverse the arrhythmia that has taken place rapidly.(3) anoxia functions that resists myocardial ischemia: Radix Aconiti Lateralis Preparata can improve hypoxia-bearing capability, and myocardial ischemia-anoxemia and arrhythmia due to the antagonism pituitrin reduce the acute myocardial ischemia damage.(4) to the influence of blood pressure and blood vessel: Radix Aconiti Lateralis Preparata can bring high blood pressure down, and improves the hypertension infringement of thoracic aorta inner membrance.(5) Antishock function: Radix Aconiti Lateralis Preparata has obvious prevention effect to multiple shock.As to endotoxin shock, can slow down its blood pressure reduction, decreased heart rate, heart contractility of Radix Aconiti Lateralis Preparata water-soluble portion such as weakens at variation, the decline degree of blood pressure, left ventricular systolic pressure power and left ventricular pressure rising maximal rate is obviously improved, and significant prolongation shock animals life span.2. to the influencing Radix Aconiti Lateralis Preparata and can obviously prolong PCT, KPTT of blood system, thrombus formation time is prolonged, function and anti-thrombosis function anticoagulant is arranged.3. capillary permeability is hyperfunction due to the antiinflammatory action inhibition acetic acid forms and adjuvant-induced arthritis with granuloma.4. aconitine on, hypaconitine, the acetylaconitine ycorynoline to the central nervous system all has analgesia, sedation.5. be part beta receptor agonist to the peripheroneural aconitine, 3-acetylaconitine, racemization demethyl coclaurine of influencing, α 1 receptor capable of blocking and exciting alpha-2 receptor and the local anesthesia effect is arranged.6. to Immune Effects the increase of spleen antibody forming cell number, serum antibody generation and rosette forming cell number and T lymhocyte transformation rate are obviously increased, so can improve immunity.7. tumor-inhibiting action crude monkshood polysaccharide and acidic polysaccharose have significant tumor-inhibiting action to H22, S180 lotus struma tumor, two kinds of polysaccharide all increase the weight of spleen, improve lymphocyte transformation ability and NK cytoactive, and then improve the expression of antioncogene P53 and Fas, impel the apoptosis rate of tumor cell.8. can antiadrenergic drug to the Radix Aconiti Lateralis Preparata that influences of intestinal smooth muscle, spontaneity that can excited intestine in vitro is shunk, but suppresses gastric emptying.
Fructus Arctii: 1. raise immunity can enhancing human body immunity function, lymhocyte transformation rate and Q-naphthyl acetate esterase positive rate are significantly improved, and can obviously increase the formation of antibody-producting cell, strengthen the phagocytic function of macrophage.2. can suppress the increase of urinary protein excretion to the effect aretigenin (diarctigenin) of nephropathy, and can improve the serum biochemistry index, anti-nephropathy effect is arranged.3. two aretigenin (diarctigenin) Arctiin (arctiin) of antitumor, antimutagenic effect) to the strong toxicity of hepatocarcinoma HepGz cell tool.4. the anti-two Fructus Arctii burdock aglycons (diarctigenin) of other effects have anti-first 1 influenza virus effect and resist the effect that influenza virus is duplicated that directly suppresses.
Styrax: Styrax is a stimulant expectorant, and more weak antibacterial action arranged, can be used for various respiratory tract infection, gentle stimulation is arranged again, can alleviate local inflammation, and can promote the healing of ulcer and wound, the effect that strengthens anoxia enduring is arranged, myocardial infarction there is decreased heart rate, improves coronary flow and reduce the myocardial oxygen consumption effect, and the effect of platelet aggregation inhibitory activity is arranged.
Fructus Gardeniae: Fructus Gardeniae decoct and alcohol extract have choleretic effect, can promote bile secretion, and can reduce blood mesobilirubin, can promote blood mesobilirubin to drain rapidly, and Hemolytic streptococcus and dermatophytes are had inhibitory action.
Realgar: 1, antibacterial action has in various degree inhibitory action to the various skin fungus in vitro with Realgar water logging agent.2, anti-schistosome function.
From the medicine comprehensive function of treatment acquired immune deficiency syndrome (AIDS), can draw following reliable definite principle:
1, jujube polysaccharide can make the phagocytic rate of macrophage and mononuclear phagocyte system and phagocytic index improve, promote lymphocyte transformation and periphery lymphocyte to decompose, the Fructus Jujubae neutral polysaccharide can promote spontaneous qualitative response and the mixed lymphocyte culture reaction of increasing of splenocyte, there is promotion to increase the matter effect to non-activated splenocyte, the multiple polysaccharide of Fructus Jujubae all makes lymphopoietic effect, with neutral polysaccharide effect the best.Astragalus polysaccharides can make that the T cell quantity increases in thymus and the spleen, and the generation of LGD more needs the T cell to participate in, and the spleen antigen binding cell of immunoreation commitment is had facilitation.The Rhizoma Atractylodis Macrocephalae can improve the function of lymphocytic emiocytosis IL-Z, can resist multiple material to lymphocytic inhibitory action, promotes lymphopoiesis.Carapax Trionycis can improve cellular immune function and lactic acid resume speed, and splenocyte conversion reflection is strengthened.The Radix Bupleuri polysaccharide can obviously improve the activity of canavaline activated spleen lymph conversion ratio and natural killer cell.Can increase Cl effect of animal carbon granules and leukocyte increasing number Radix Ophiopogonis.Tremella can increase blood carbon Cl, can improve splenocyte and periphery T cell positive rate, can improve lymphocyte and liver superoxides limb enzymatic activity, promote the generation of above-mentioned cytokine, increase the concentration of free calcium ions in the splenocyte, and coordinate the elimination HIV effect of various immunologic functions, the syncytium that immunodeficiency virus is caused has inhibitory action.Radix Angelicae Sinensis has the spleen of promotion and the lymphopoietic effect of thymus T.B, can strengthen the lethal merit 80% of cytotoxic T cell, can resist multiple medicine and the virus inhibitory action to thymus and splenic T lymphproliferation response; Radix Angelicae Sinensis polysaccharide can promote splenocyte weightening finish and antibody quantity to increase, and assists the interior immunity of body to play higher efficient, and liver, spleen kidney, lung are all had good protective effect.Fructus Lycii is fried in shallow oil soup with the 5-15 gram TB lymphocyte factor is two-way function, can increase the quantity and the vigor of macrophage C3B and FE receptor, can improve the killing ability of lymphocytic propagation function of splenic T and cytotoxic T cell, can resist multiple medicine and the virus immunosuppressive action to T lymphocyte and natural killer cell, the leukocyte that chemicotherapy, X line are caused has therapeutical effect.The Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) is carried to such an extent that neostellin can suppress the infection of HIV-1 and MT-4 cell from Stellera chamaejasme L., and stronger HIV (human immunodeficiency virus)-resistant activity is arranged.The ginsenoside is to bacteria lipopolysaccharide sugar and concanavalin A cconA, the lymphocyte transformation that stimulates has significant potentiation, lymphocyte transformation to various mitosis primary stimulis during 1mg/ml concentration has tangible potentiation, can make it recover normal level fully, can strengthen the generation of spleen and thymus T proliferation of lymphocytes and interleukin, the reticuloendothelial system phagocytic function all there is tangible activation and engulfs the ability of cleaning up, the weight and the phagocyte phagocytic activity of energy enhance immunity organ, can strengthen the weight of spleen, the anti-lgh of specificity is obviously raise; Radix Ginseng can also slow down aging.Aloe polysaccharide can strengthen lymphocytic differentiation of TB and propagation, and macrophage is strengthened facilitation.Obviously mitosis promoting is former in the lymphocytic propagation of splenic T for Semen Armeniacae Amarum, promotes the NK cell activity, promotes PHA to stimulate lymphocytic conversion of T and propagation.The bright Radix Rehmanniae can promote activatory splenocyte DNA of con A and proteinic biosynthesis, strengthening interleukin-2 produces, can promote the phagocytic function of macrophage, lymphocyte expression of ALP ability is strengthened, can make hematopoietic stem cell, bone marrow hemopoietic progenitor cell of red blood cell line differentiation and proliferation.The glycyrrhizic acid of Radix Glycyrrhizae, monoamine can be killed HIV (human immunodeficiency virus), the Monosodium glycyrrhetin T lymphocyte ratio that can raise, lymphocyte expression of ALP ability is increased, cruor time extending, can promote the biosynthesis of activatory splenocyte PNA of con A and egg matter, increase interleukin-2 and produce, can improve the phagocytic function of the low macrophage of animal immunizing power.Flos Lonicerae has inhibitory action to various bacteria virus, improve its leukopenia that causes and reduce body temperature,, and strengthen leukocyte and inflammatory cell phagocytic function the pathological lesion of liver, remove multiple endotoxin, the stimulating central nervous system system is to the cytotoxicity of tumor cell.Fructus Forsythiae fat glycosides and phillyrin have antibacterial activity to various bacteria virus, and antiemetic effect and hepatoprotective effect are arranged, and treatment diabetes and hypotensive effect are arranged.Radix Scutellariae can be brought into play killing action to various bacteria virus by the signal and communication path of blocking-up cell, and the cem cell of HIV virus is had the significant cytotoxicity effect.Can send the function of sticking of cellular immune function and promotion erythrocyte immune, the heart, liver, kidney, brain, marrow are had protective effect.Flos Rosae Rugosae can be improved microvascular blood flow rate, improves the ischemic state of heart, and long stalk aristin that Flos Rosae Rugosae contains and new suona horn element are to immunodeficiency virus, and leucovirus has antivirus action.Total alkaloids of meadowrueleaf corydalis root can strengthen haemolysis speckle value, can strengthen the Mixed culture reaction of spleen and the breeder reaction of mitosis primary stimuli splenocyte.Can strengthen the T cell and produce IL-2 and IFN-r level, can reduce striatum dihydroxyphenyl acetic acid, 4-hydroxy-3-methoxy-.alpha.-toluic acid., 5-hydroxyl color acid content and play the spasmolysis and analgesia effect, and play therapeutical effect acquired immune deficiency syndrome (AIDS).
As seen, as above medicine has inhibition, kills the HIV (human immunodeficiency virus) effect; On this basis, strengthen immunity again again, particularly strengthened the effect of the lymphocytic inhibition virus and bacteria of T, played the adenoid effect of HIV (human immunodeficiency virus) destruction T4 that prevents; The medicine that also has kill bacteria virus has been prevented bacterial virus to take advantage of HIV (human immunodeficiency virus) and has been destroyed the probability that the power traction of immunologic function plays multiple disease.So played the effect of good treatment acquired immune deficiency syndrome (AIDS).
Cause death on the basis of reason having solved as above HIV (human immunodeficiency virus), also have following important function:
2, according to the prescription 2 of change of illness state, can heat-clearing and toxic substances removing, the heat radiation of inducing sweat will remain in intravital toxin and excrete.Alleviate muscle spasm, remove pain, alleviate the effect of burden at heart.
3, remove pulmonary's bronchitis, separate gas removing pipe, bronchus, spasm and play the effect of relieving cough and asthma, pharynx-clearing throat-benefiting is more arranged, the effect of detoxifcation pathogenic fire reducing.
4, can remove melancholyly, eliminate dysphoria with smothery sensation in the heart, have and well moisten intestinal, the catharsis and toxin expelling effect, and the function of inflammation such as eliminating serious oral cavity, throat is arranged.
5, for ischemia, can strengthen multiple hemopoietic function, make myeloid lineage erythrocyte hematopoietic cell proliferation, break up enhanced effect, blood volume in the added body has superoxide dismutase activity improving, the effect of serum Total antioxidant capacity and enhancing hematid immunity function.
But 6 spleen invigorating QI invigorating, invigorating the liver and kidney, beneficial marrow in case cold and cool medicine hinders healthy energy, decreases Liver and kidney, improve immune system the cognitive ability of HIV are produced resistance, eliminate HIV virus.
7, the clear refreshing refreshment of energy makes sx, and feels to have the sensation of demutation, no longer is in the state of being nervous, and plays better therapeutical effect.
8, this medicine also has the effect of blood circulation promoting and blood stasis dispelling, the body of decaying that HIV (human immunodeficiency virus) is caused, and resistance weakens, and few motion, and the internal organs dissipations such as causing the blood stasis occluding vascular that decays, and can make unobstructed vessel, so that medicine plays better therapeutical effect.
9, can spleen benefiting and stimulating the appetite, stimulating appetite and being healthy and strong in case become thin, can make the big weightening finish of the dirty Long of spleen, and enhancing immunity strengthens the ability of T lymphocyte and phagocyte understanding HIV (human immunodeficiency virus) and eliminates HIV (human immunodeficiency virus), reaches the purpose of treatment of AIDS.
10, medicines such as Flos Rosae Rugosae, Herba Cynomorii, Spica Prunellae, Fructus Chebulae, Radix Arnebiae (Radix Lithospermi), Radix Glycyrrhizae, Flos Chrysanthemi, Rhizoma Dioscoreae, the Radix Astragali, Rhizoma Polygonati, the Rhizoma Atractylodis Macrocephalae, JIESHESHU, Rhizoma Chuanxiong, Rhizoma Curcumae share; played the vital organs of the human body and the good especially protective effects of whole body such as the heart, liver, spleen, lung, kidney, brains, gallbladder, intestinal, stomach, blood; not only played the effect that suppresses to kill acquired immune deficiency syndrome (AIDS); can also strengthen to HIV (human immunodeficiency virus) recognize with and immunogenicity; can bring out and promote the immunological effect of body, can make the part animal obtain good protective effect really HIV (human immunodeficiency virus).
11, used the medicine of washout simultaneously, HIV (human immunodeficiency virus) and other bacterial viruses of body surface have not only been killed, the medicine of skin absorbs is along with the past cardiovascular of blood capillary, solved and when the medicine of the intestines and stomach absorption carefully is recycled to body surface, killed the insufficient shortcoming of HIV (human immunodeficiency virus), played from the inside to surface, the effect of two-way pincer attack HIV (human immunodeficiency virus) from outside to inside, so better effects if.
12, used differential diagnosis in tcm to execute the characteristics of controlling, caused multiple symptom to be divided into to human body according to HIV (human immunodeficiency virus):
(1) enhancing immunity, to kill HIV (human immunodeficiency virus) be main square medicine, according to the sense just of dialectical being varied to (2) acquired immune deficiency syndrome (AIDS) the pain relieving of inducing sweat, relieving cough and asthma, ascending the clear and descending the turbid arranged, the also square medicine of enhancing immunity simultaneously.Improving immunity according to dialectical being varied to (3) is the main thorough treatment of AIDS of prescription in conjunction with killing the HIV (human immunodeficiency virus) medicine.And the medicine of washout is divided into the disease side of having a bath of (1) cold and cool weakness; Specially control the acquired immune deficiency syndrome (AIDS) of table disease and damp-heat syndrome according to the in addition upright side of having a bath (2) of change of illness state.
With the method treatment acquired immune deficiency syndrome (AIDS) people more than 30, all played satisfied curative effect.Because of heavy patient is reluctant the name public affairs are seen in the crowd, so do not say name herein.
The specific embodiment
Following HIV sufferers is all used 1 extra wash elder generation washout 6-10 days, serves as that the master alternately washes recovery from illness with No. 1 medicine with 2 extra wash again.
Case 1 clock * county town, * 30 years old women Panzhihua City Miyi County
Blood test: code name HIV project HIV antibody is the positive (+) as a result
Symptom: continue fever, body temperature reaches 39.8 ℃ sometimes, often remain on 37.6 ℃-38.3 ℃, often cough, tell yellow sputum, chest pain, systemic pain, dizzy weak, be unable to leave the bed, weakness, night sweat, whole body superficial lymph tie enlargement, body weight descended within three months 23 kilograms, it is obvious especially to become thin, dyspnea, complexion is purple black, restlessness and thirst, dimly red tongue, yellowish fur, thready and rapid pulse.Control with heat-clearing and toxic substances removing, the heat radiation of inducing sweat the flesh pain relieving of relaxing, lung qi dispersing cough-relieving, pharynx-clearing throat-benefiting, detoxifcation pathogenic fire reducing, YIN nourishing relieving restlessness, promoting the production of body fluid to quench thirst, loosening bowel to relieve constipation, blood circulation promoting and blood stasis dispelling, suitably enrich blood ascending the clear and descending the turbid, soothing liver-QI expelling pathogenic factors from muscles, the spleen invigorating QI invigorating, invigorating the liver and kidney, all methods of beneficial marrow start at the same time, in case cold and cool medicine is hindered healthy energy, decreased Liver and kidney, improve immune system the cognitive ability of HIV is produced resistance, eliminate HIV virus; Spleen benefiting and stimulating the appetite stimulating appetite and being healthy and strong in case become thin, the energy enhancing immunity makes the big weightening finish of the dirty Long of spleen, can prevent the T lymphoid tissue among the HIV (human immunodeficiency virus) destruction human immune system especially, strengthen macrophage phagocytic function, to defeat bacterial virus and HIV infringement to human body.
At first with washout 1 side 4 orders of having a bath, 2 side's medicines for oral administration simultaneously: Herba Hedyotidis Diffusae 30, Flos Lonicerae 26, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 16, Herba Taraxaci 30, Fructus Forsythiae 20, Radix Asparagi 10, Radix Ophiopogonis 10, the bright Radix Rehmanniae 20, Radix Scrophulariae 15, Semen Persicae 12, Rhizoma Chuanxiong 9, Rhizoma Curcumae 15, Radix Achyranthis Bidentatae 12, pollen 16, Radix Salviae Miltiorrhizae 60, Cortex Moutan 10, Radix Bupleuri 10, Fructus Aurantii 12, Pericarpium Citri Reticulatae 10, Fructus Amomi 10, Cortex Magnoliae Officinalis 20, Flos Rosae Rugosae 12, Herba Cynomorii 10, Spica Prunellae 15, the Fructus Chebulae 10, Radix Arnebiae (Radix Lithospermi) 18, Radix Glycyrrhizae 12, Flos Chrysanthemi 12, Semen Ricini 1,6 in bull frog gallbladder, Radix Scutellariae 12, Massa Medicata Fermentata 15, Fructus Hordei Germinatus 20, Fructus Setariae Germinatus 20, Endothelium Corneum Gigeriae Galli 10, Semen Raphani 12, Rhizoma Dioscoreae 30, the Radix Astragali 30, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Polygonati 12, Radix Codonopsis 36, Fructus Crataegi 22, Poria 30,10 in Fructus Jujubae, Herba Cistanches 10, Radix Angelicae Sinensis 10, Caulis Spatholobi 15, Colla Corii Asini 32, Caulis Perillae 10, Herba Schizonepetae 10, Herba Menthae 10, Radix Gentianae Macrophyllae 12, the Radix Angelicae Dahuricae 8, Radix Asteris 10, Bulbus Fritillariae Uninbracteatae 10, Radix Platycodonis 10.Totally 10 doses, what body temperature was stable returns to 36.5 ℃, not cough again, and whole body does not have pain, and spirit take a favorable turn, and diet increases, and breathes steadily, and the lymph node of enlargement alleviates; Then using washout 2 sides instead had a bath 118 days, 1 side's medicine Herba Hedyotidis Diffusae 30 for oral administration, Flos Lonicerae 26, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 16, Herba Taraxaci 30, Fructus Forsythiae 20, Radix Asparagi 10, Radix Ophiopogonis 10, the bright Radix Rehmanniae 20, Radix Scrophulariae 15, Semen Persicae 12, Rhizoma Chuanxiong 9, Rhizoma Curcumae 15, Radix Achyranthis Bidentatae 12, pollen 16, Radix Salviae Miltiorrhizae 60, Cortex Moutan 10, Radix Bupleuri 10, Fructus Aurantii 12, Pericarpium Citri Reticulatae 10, Fructus Amomi 10, Cortex Magnoliae Officinalis 20, Flos Rosae Rugosae 12, Herba Cynomorii 10, Spica Prunellae 15, the Fructus Chebulae 10, Radix Arnebiae (Radix Lithospermi) 18, Radix Glycyrrhizae 12, Flos Chrysanthemi 12, Semen Ricini 1,6 in bull frog gallbladder, Radix Scutellariae 12, Massa Medicata Fermentata 15, Fructus Hordei Germinatus 20, Fructus Setariae Germinatus 20, Endothelium Corneum Gigeriae Galli 10, Semen Raphani 12, Rhizoma Dioscoreae 30, the Radix Astragali 18, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Polygonati 12, Radix Codonopsis 36, Fructus Crataegi 22, Poria 30,10 in Fructus Jujubae, Herba Cistanches 30, Radix Angelicae Sinensis 10, Caulis Spatholobi 15, Colla Corii Asini 16, obeyed altogether 32 days, spirit takes a turn for the better, have rosy cheeks, diet is normal, and lymph node also has the small part enlargement; 3 side's medicine Herba Hedyotidis Diffusaes 30 then for oral administration, Flos Lonicerae 26, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 16, Herba Taraxaci 30, Fructus Forsythiae 20, Radix Asparagi, Radix Ophiopogonis 10, the bright Radix Rehmanniae 20, Radix Scrophulariae 15, Semen Persicae 12, Rhizoma Chuanxiong 9, Rhizoma Curcumae 15, Radix Achyranthis Bidentatae 12, pollen 16, Radix Salviae Miltiorrhizae 60, Cortex Moutan 10, Radix Bupleuri 10, Fructus Aurantii 12, Pericarpium Citri Reticulatae 10, Fructus Amomi 10, Cortex Magnoliae Officinalis 20, Flos Rosae Rugosae 12, Herba Cynomorii 10, Spica Prunellae 15, the Fructus Chebulae 10, Radix Arnebiae (Radix Lithospermi) 18, Radix Glycyrrhizae 12, Flos Chrysanthemi 12, Semen Ricini 1,6 in bull frog gallbladder, Radix Scutellariae 12, Massa Medicata Fermentata 15, Fructus Hordei Germinatus 20, Fructus Setariae Germinatus 20, Endothelium Corneum Gigeriae Galli 10, Semen Raphani 12, Rhizoma Dioscoreae 30, the Radix Astragali 18, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Polygonati 12, Radix Codonopsis 36, Fructus Crataegi 22, Poria 30,10 in Fructus Jujubae, Herba Cistanches 30, Radix Angelicae Sinensis 10, Caulis Spatholobi 15, Colla Corii Asini 16, Carapax Trionycis 30, Radix Rehmanniae Preparata 16, Fructus Corni 12, Tremella 30, Fructus Lycii 10, Os Draconis 26, Concha Ostreae 30, Herba Epimedii 12, Rhizoma Curculiginis 20, Colla cornus cervi 12, Radix Ginseng 10, Herba Patriniae 20, brave zhang 18, Bombyx Batryticatus 15, Radix Isatidis 12, the Radix Paeoniae Alba 12, Rhizoma Polygonati Odorati 12, Fructus Alpiniae Oxyphyllae 10, Herba Taxilli 10, Carapax et Plastrum Testudinis 30, Fructus Ligustri Lucidi 15, Concha Ostreae 30, Rhizoma Cimicifugae 12, obeyed altogether 90 days, clock * * physical recovery health, glowing with health, do not see enlarged lymph node.
Clock * * HIV antibody feminine gender (-) as a result tested through sanguification
(illustrate: 1 side of the said treatment acquired immune deficiency syndrome (AIDS) of following each case, 2 sides, 3 sides' medicine is as the criterion with case 1 said ingredient, because of the length relation no longer repeats the content of writing out a prescription.)
Case 2 is * * 37 years old Xichang City Xiao Miao township, male Sichuan Province
Blood test: code name HIV project HIV antibody is the positive (+) as a result
Symptom: dizziness, headache, weakness, long-term cough, chest pain, dyspnea, groin and pancreas reach the breast lymphonodi abdominales down and grow up, sputum mixed with blood when serious, nausea and vomiting, stool band blood.
This patient's lung, stomach, large intestine sustains damage and hemorrhage, took No. 2 medicines 6 days so earlier fry in shallow oil soup with Rhizoma Imperatae 30g, Nodus Nelumbinis Rhizomatis 20g, charred Flos Sophorae 10g, Radix Sanguisorbae 10g, Radix Rubiae 10g, Fructus Trichosanthis 20g, Platycladi Cacumen carbonisatum 15g, Caulis Bambusae In Taenia 10g, Pericarpium Citri Reticulatae 10g, Poria 20g, Fructus Aurantii Immaturus 15g, Rhizoma Pinelliae 10g, Flos Inulae 10g, Cortex Dictamni 15g, Spica Prunellae 15g, Fructus Amomi 6g, hemorrhage, cough, chest pain, feel sick, symptom eliminations such as vomiting, dyspnea; Then took No. 1 medicine 40 days, energetic, have rosy cheeks; Take No. 3 medicines 80 days again and test HIV antibody feminine gender (-) as a result through sanguification
Case 3 poplars * Dayu County He Dong township, * 43 years old male Jiangxi Province
Blood test: code name HIV project HIV antibody is the positive (+) as a result
Symptom: appetite decline, anorexia, diarrhoea.Dizziness, headache, bradykinesia, the hypophrenia, psychological problem, the whole body pruritus.This patient as above all diseases occur owing to HIV has damaged nervous system, thus at first took No. 1 medicine 32 days, god control clear-headed after, then took No. 3 medicines 80 days, hale and hearty, glowing with health,
Test HIV antibody feminine gender (-) as a result through sanguification, recovered work.
Case 4 fields * Kai Xian, women Chongqing City pressed down near a river in * 39 years old
Blood test: code name HIV project HIV antibody is the positive (+) as a result
Symptom: skin damages easily, hinders the back haemophilia, continues fever, weak, night sweat, and appetite descends, shape food, the nervous heart are tired, feels dizzy, fatigue and weak, drowsiness, bradykinesia, the hypophrenia.
This patient sustains damage because of the heart, liver, spleen, lung, kidney, QI and blood, and antisecosis is in vigorous health so reused 1 side and 3 sides each 80 days alternately for oral administration, and spirit extraordinarily, and is glowing with health, through chemical examination HIV antibody feminine gender (-) as a result
Case 5 week * Yan Ling town, Weiyuan County, * 42 years old women Sichuan
Blood test: code name HIV project HIV antibody is the positive (+) as a result
Symptom: oral cavity and pharyngeal mucosa inflammation occurs even fester, and red or mauve macule appear in body surface, cough, breathe hard, persistence diarrhoea, have blood in stool, hepatosplenomegaly, dyspnea.
This patient has attacked immune organ in HIV, vulnerable, and bacterial virus invasion and attack oropharynx occurs and arrive and fester, and infringement lung, harmonization of the stomach liver spleen, so at first take 1 side for oral administration after 20 days, then the main formula medicine that closes treatment hepatitis, liver cirrhosis and the hepatocarcinoma of my invention with 2 reef knots for oral administration was taken 160 days and was fully recovered, and tested HIV antibody feminine gender (-) as a result through sanguification, recovered normal through color ultrasonic diagnosis liver spleen.
Case 6 Cao * Qiaojia County Shuan He town, * 41 years old women Yunnan Province
Blood test: code name HIV project HIV antibody is the positive (+) as a result
Symptom: hyperpyrexia, headache, disturbance of consciousness, tic, it is unable to suffer from diarrhoea, suffer from abdominal pain, become thin, anorexia, lasting fever is not moved back, visual deterioration.
This patient is because of HIV invasion and attack T4 lymphsystem bacterial infection virus; injured nerve system and cause symptoms such as disturbance of consciousness, tic; so with Bombyx Batryticatus 10g, Rhizoma Gastrodiae 15g, Scolopendra 2g (foot of decaptitating), Scorpio 2g (foot of decaptitating), Radix Saposhnikoviae 5g, Rhizoma Et Radix Notopterygii 5g, Radix Gentianae Macrophyllae 8g, Radix Curcumae 12g, Cornu Bubali 10g, water Cinnabaris 0.1g, Fructus Gardeniae 12g, Radix Scutellariae 12g, fry in shallow oil mixing in water for oral taking Calculus Bovis 1g, Moschus 0.1g, Borneolum Syntheticum 0.1g; promptly clear-headed about 10 minutes; brothers do not knot; medicine 2 sides for oral administration that take the treatment acquired immune deficiency syndrome (AIDS) again took 1 side for oral administration 90 days after 16 days.Then took each 50 days for handing over, through chemically examining HIV antibody feminine gender (-) as a result with 3 degrees for oral administration.

Claims (10)

1. according to the endo-medicine of acquired immune deficiency syndrome (AIDS) that claim 1 is treated, it is characterized in that comprising by weight following component: Herba Hedyotidis Diffusae 30, Flos Lonicerae 26, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 16, Herba Taraxaci 30, Fructus Forsythiae 20, Radix Asparagi 10, Radix Ophiopogonis 10, the bright Radix Rehmanniae 20, Radix Scrophulariae 15, Semen Persicae 12, Rhizoma Chuanxiong 9, Rhizoma Curcumae 15, Radix Achyranthis Bidentatae 12, pollen 16, Radix Salviae Miltiorrhizae 60, Cortex Moutan 10, Radix Bupleuri 10, Fructus Aurantii 12, Pericarpium Citri Reticulatae 10, Fructus Amomi 10, Cortex Magnoliae Officinalis 20, Flos Rosae Rugosae 12, Herba Cynomorii 10, Spica Prunellae 15, the Fructus Chebulae 10, Radix Arnebiae (Radix Lithospermi) 18, Radix Glycyrrhizae 12, Flos Chrysanthemi 12, Semen Ricini 1,6 in bull frog gallbladder, Radix Scutellariae 12, Massa Medicata Fermentata 15, Fructus Hordei Germinatus 20, Fructus Setariae Germinatus 20, Endothelium Corneum Gigeriae Galli 10, Semen Raphani 12, Rhizoma Dioscoreae 30, the Radix Astragali 18, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Polygonati 12, Radix Codonopsis 36, burnt short, bristly hair or beard 22, Poria 30,10 in Fructus Jujubae, Herba Cistanches 30, Radix Angelicae Sinensis 10, Caulis Spatholobi 15, Colla Corii Asini 32.
2. according to the medicine of acquired immune deficiency syndrome (AIDS) that claim 1 is treated, it is characterized in that comprising by weight following component: Herba Hedyotidis Diffusae 0.1-300, Flos Lonicerae 0.1-300, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.1-300, Herba Taraxaci 3-500, Fructus Forsythiae 3-300, Radix Asparagi 0.1-200, Radix Ophiopogonis 0.1-250, bright Radix Rehmanniae 0.1-300, Radix Scrophulariae 1-500, Semen Persicae 1-300, Rhizoma Chuanxiong 1-300, Rhizoma Curcumae 1-300, Radix Achyranthis Bidentatae 1-300, pollen 1-250, Radix Salviae Miltiorrhizae 0.1-900, Cortex Moutan 1-200, Radix Bupleuri 0.1-3000, Fructus Aurantii 1-300, Pericarpium Citri Reticulatae 0.1-300, Fructus Amomi 0.1-300, Cortex Magnoliae Officinalis 5-300, Flos Rosae Rugosae 1-200, Herba Cynomorii 0.1-300, Spica Prunellae 0.1-500, Fructus Chebulae 0.1-500, Radix Arnebiae (Radix Lithospermi) 1-500, Radix Glycyrrhizae 0.1-1000, Flos Chrysanthemi 0.1-1000, Semen Ricini 0.001-300, bull frog gallbladder 0.1-1180, Radix Scutellariae 0.1-300, Massa Medicata Fermentata 0.1-1400, Fructus Hordei Germinatus 0.1-1400, Fructus Setariae Germinatus .01-1400, Endothelium Corneum Gigeriae Galli 0.1-1200, Semen Raphani 0.1-1000, Rhizoma Dioscoreae 0.1-3000, Radix Astragali 0.1-2000, Rhizoma Atractylodis Macrocephalae 0.1-2000, Rhizoma Polygonati 0.1-2000, Radix Codonopsis 0.1-3000, burnt short, bristly hair or beard 0.01-2000, Poria 0.1-5000, Fructus Jujubae 0.01-2000, Herba Cistanches 0.1-1000, Radix Angelicae Sinensis 0.01-4000, Caulis Spatholobi 0.1-3000, Colla Corii Asini 0.1-400.
3. according to the medicine of acquired immune deficiency syndrome (AIDS) that claim 1 is treated, it is characterized in that comprising by weight following component: Herba Hedyotidis Diffusae 30, Flos Lonicerae 26, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 16, Herba Taraxaci 30, Fructus Forsythiae 20, Radix Asparagi 10, Radix Ophiopogonis 10, the bright Radix Rehmanniae 20, Radix Scrophulariae 15, Semen Persicae 12, Rhizoma Chuanxiong 9, Rhizoma Curcumae 15, Radix Achyranthis Bidentatae 12, pollen 16, Radix Salviae Miltiorrhizae 60, Cortex Moutan 10, Radix Bupleuri 10, Fructus Aurantii 12, Pericarpium Citri Reticulatae 10, Fructus Amomi 10, Cortex Magnoliae Officinalis 20, Flos Rosae Rugosae 12, Herba Cynomorii 10, Spica Prunellae 15, the Fructus Chebulae 10, Radix Arnebiae (Radix Lithospermi) 18, Radix Glycyrrhizae 12, Flos Chrysanthemi 12, Semen Ricini 1,6 in bull frog gallbladder, Radix Scutellariae 12, Massa Medicata Fermentata 15, Fructus Hordei Germinatus 20, Fructus Setariae Germinatus 20, Endothelium Corneum Gigeriae Galli 10, Semen Raphani 12, Rhizoma Dioscoreae 30, the Radix Astragali 30, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Polygonati 12, Radix Codonopsis 36, burnt short, bristly hair or beard 22, Poria 30,10 in Fructus Jujubae, Herba Cistanches 10, Radix Angelicae Sinensis 10, Caulis Spatholobi 15, Colla Corii Asini 16, Caulis Perillae 10, Herba Schizonepetae 10, Herba Menthae 10, Radix Gentianae Macrophyllae 12, the Radix Angelicae Dahuricae 8, Radix Asteris 10, Bulbus Fritillariae Uninbracteatae 10, Radix Platycodonis 10.
4. according to the medicine of acquired immune deficiency syndrome (AIDS) that claim 3 is treated, it is characterized in that comprising by weight following component: Herba Hedyotidis Diffusae 0.1-300, Flos Lonicerae 0.1-300, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.1-300, Herba Taraxaci 3-500, Fructus Forsythiae 3-300, big winter 0.1-200, Radix Ophiopogonis 0.1-250, bright Radix Rehmanniae 0.1-300, Radix Scrophulariae 1-500, Semen Persicae 1-300, Rhizoma Chuanxiong 1-300, Rhizoma Curcumae 1-300, Radix Achyranthis Bidentatae 1-300, pollen 1-250, Radix Salviae Miltiorrhizae 0.1-900, Cortex Moutan 1-200, Radix Bupleuri 1-300, Fructus Aurantii 1-300, Pericarpium Citri Reticulatae 0.1-300, Fructus Amomi 0.1-300, Cortex Magnoliae Officinalis 5-300, Flos Rosae Rugosae 1-200, Herba Cynomorii 0.1-300, Spica Prunellae 0.1-500, Fructus Chebulae 0.1-500, Radix Arnebiae (Radix Lithospermi) 1-500, Radix Glycyrrhizae 0.1-1000, Flos Chrysanthemi 0.1-1000, Semen Ricini 0.001-300, living frog gallbladder 0.1-1180, Radix Scutellariae 0.1-300, Massa Medicata Fermentata 0.1-1400, Fructus Hordei Germinatus 0.1-1400, Fructus Setariae Germinatus .01-1400, Endothelium Corneum Gigeriae Galli 0.1-1200, Semen Raphani 0.1-1000, Rhizoma Dioscoreae 0.1-3000, Radix Astragali 0.1-2000, Rhizoma Atractylodis Macrocephalae 0.1-2000, Rhizoma Polygonati 0.1-2000, Radix Codonopsis 0.1-3000, burnt short, bristly hair or beard 0.01-2000, Poria 0.1-5000, Fructus Jujubae 0.01-2000, Herba Cistanches 0.1-1000, Radix Angelicae Sinensis 0.01-4000, Caulis Spatholobi 0.1-3000, Colla Corii Asini 0.1-400, Caulis Perillae 1-100, Herba Schizonepetae 1-100, PUHE 1-100, Radix Gentianae Macrophyllae 1-100, Radix Angelicae Dahuricae 1-100, Radix Asteris 0.1-50, Bulbus Fritillariae Uninbracteatae 0.1-30, Radix Platycodonis 3-30.
5. according to the medicine of acquired immune deficiency syndrome (AIDS) that claim 1 is treated, it is characterized in that comprising by weight following component: Herba Hedyotidis Diffusae 30, Flos Lonicerae 26, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 16, Herba Taraxaci 30, Fructus Forsythiae 20, Radix Asparagi 10, Radix Ophiopogonis 10, the bright Radix Rehmanniae 20, Radix Scrophulariae 15, Semen Persicae 12, Rhizoma Chuanxiong 9, Rhizoma Curcumae 15, Radix Achyranthis Bidentatae 12, pollen 16, Radix Salviae Miltiorrhizae 60, Cortex Moutan 10, Radix Bupleuri 10, Fructus Aurantii 12, Pericarpium Citri Reticulatae 10, Fructus Amomi 10, Cortex Magnoliae Officinalis 20, Flos Rosae Rugosae 12, Herba Cynomorii 10, Spica Prunellae 15, the Fructus Chebulae 10, Radix Arnebiae (Radix Lithospermi) 18, Radix Glycyrrhizae 12, Flos Chrysanthemi 12, Semen Ricini 1,6 in bull frog gallbladder, Radix Scutellariae 12, Massa Medicata Fermentata 15, Fructus Hordei Germinatus 20, Fructus Setariae Germinatus 20, Endothelium Corneum Gigeriae Galli 10, Semen Raphani 12, Rhizoma Dioscoreae 30, the Radix Astragali 18, the Rhizoma Atractylodis Macrocephalae 15, Rhizoma Polygonati 12, Radix Codonopsis 36, burnt short, bristly hair or beard 22, Poria 30,10 in Fructus Jujubae, Herba Cistanches 30, Radix Angelicae Sinensis 10, Caulis Spatholobi 15, Colla Corii Asini 16, Carapax Trionycis 30, Radix Rehmanniae Preparata 16, by Fructus Corni 12, Tremella 30, Fructus Lycii 10, Os Draconis 26, Concha Ostreae 30, Herba Epimedii 12, Rhizoma Curculiginis 20, Colla cornus cervi 12, Radix Ginseng 10, Herba Patriniae 20, brave zhang 18, Bombyx Batryticatus 15, Radix Isatidis 12, the Radix Paeoniae Alba 12, Rhizoma Polygonati Odorati 12, Fructus Alpiniae Oxyphyllae 10, Herba Taxilli 10, Carapax et Plastrum Testudinis 30, Fructus Ligustri Lucidi 15, Concha Ostreae 30, Rhizoma Cimicifugae 12.
6. according to the medicine of acquired immune deficiency syndrome (AIDS) that claim 5 is treated, it is characterized in that comprising by weight following component: Herba Hedyotidis Diffusae 0.1-300, Flos Lonicerae 0.1-300, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 0.1300, Herba Taraxaci 3-500, Fructus Forsythiae 3-300, Radix Asparagi 0.1-200, Radix Ophiopogonis 0.1-250, bright Radix Rehmanniae 0.1-300, Radix Scrophulariae 1-500, Semen Persicae 1-300, Rhizoma Chuanxiong 1-300, Rhizoma Curcumae 1-300, Radix Achyranthis Bidentatae 1-300, pollen 1-250, Radix Salviae Miltiorrhizae 0.1-900, Cortex Moutan 1-200, Radix Bupleuri 1-300, Fructus Aurantii 1-300, Pericarpium Citri Reticulatae 0.1-300, Fructus Amomi 0.1-250, Cortex Magnoliae Officinalis 5-300, Flos Rosae Rugosae 1-20, Herba Cynomorii 0.1-300, Spica Prunellae 0.1-500, Fructus Chebulae 0.1-500, Radix Arnebiae (Radix Lithospermi) 1-500, Radix Glycyrrhizae 0.1-100, Flos Chrysanthemi 0.1-1000, Semen Ricini 0.001-300, bull frog gallbladder 0.1-1180, Radix Scutellariae 0.1-300, Massa Medicata Fermentata 0.1-1400, Fructus Hordei Germinatus 0.1-1400, Fructus Setariae Germinatus 01-1400, Endothelium Corneum Gigeriae Galli 0.1-1200, Semen Raphani 0.1-1000, Rhizoma Dioscoreae 0.1-3000, Radix Astragali 0.1-2000, Rhizoma Atractylodis Macrocephalae 0.1-2000, Rhizoma Polygonati 0.1-2000, Radix Codonopsis 0.1-3000, burnt short, bristly hair or beard 0.01-2000, Poria 1-200, Fructus Jujubae 0.01-2000, Herba Cistanches 1-100, Radix Angelicae Sinensis 0.01-4000, Caulis Spatholobi 0.1-3000, Colla Corii Asini 0.1-400, Carapax Trionycis 1-200, Radix Rehmanniae Preparata 1-100, Fructus Corni 1-100, Tremella 1-100, Fructus Lycii 1-100, Os Draconis 1-100, Concha Ostreae 1-100, Herba Epimedii 1-200, Rhizoma Curculiginis 1-100, Colla cornus cervi 1-100, Radix Ginseng 1-200, Herba Patriniae 1-2000, tiger zhang 1-500, Bombyx Batryticatus 1-200, Radix Isatidis 1-1000, Radix Paeoniae Alba 1-200, Rhizoma Polygonati Odorati 1-200, Fructus Alpiniae Oxyphyllae 1-200, Herba Taxilli 1-100, Carapax et Plastrum Testudinis 1-100, Fructus Ligustri Lucidi 1-100, Concha Ostreae 3-60, Rhizoma Cimicifugae 2-300.
7. according to the washout medicine of acquired immune deficiency syndrome (AIDS) that claim 1 is treated, it is characterized in that comprising by weight following component: Radix Et Rhizoma Rhei 100, JIESHESHU 100, Flos Rosae Rugosae 100, pollen 200, Flos Chrysanthemi 160, Spica Prunellae 80, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 60,30 in bull frog gallbladder, Cortex Phellodendri 70, Radix Scutellariae 60, Rhizoma Coptidis 60, Fructus Gardeniae 60, Flos Lonicerae 100, Radix Sophorae Flavescentis 70, Rhizoma Smilacis Glabrae 60, brave zhang 60, Herba Violae 100, Fructus Forsythiae 70g, Radix Sophorae Tonkinensis 60, white portion 100, Rhizoma Paridis 100, Herba Scutellariae Barbatae 50, Rhizoma Osmundae 50, Oldenlandia diffusa Roxb 150, Herba Solani Lyrati 130, Radix Saposhnikoviae 60, larval moult 60, Herba Schizonepetae 60, the Radix Angelicae Dahuricae 30, Camphora 1, Borneolum Syntheticum 1, Spina Gleditsiae 60, Flos Caryophylli 60.
8. according to the washout medicine of acquired immune deficiency syndrome (AIDS) that claim 7 is treated, it is characterized in that comprising by weight following component: Radix Et Rhizoma Rhei 1-500, JIESHESHU 1-200, Flos Rosae Rugosae 1-200, pollen 1-400, Flos Chrysanthemi 1-300, Spica Prunellae 1-500, Corydalis thalictrifolia Franch. (Radix Corydalis Thalictrifoliae) 1-200, bull frog gallbladder 0.1-1180, Cortex Phellodendri 1-300, Radix Scutellariae 1-300, Rhizoma Coptidis 1-200, Fructus Gardeniae 1-200, Flos Lonicerae 1-500, Radix Sophorae Flavescentis 1-200, Rhizoma Smilacis Glabrae 1-100, tiger zhang 1-200, Herba Violae 1-300, Fructus Forsythiae 1-200, Radix Sophorae Tonkinensis 1-300, the white 1-300 of portion, Rhizoma Paridis 1-200, Herba Scutellariae Barbatae 1-500, Rhizoma Osmundae 1-200, Oldenlandia diffusa Roxb 1-300, Herba Solani Lyrati 1-300, Radix Saposhnikoviae-200, larval moult 1-200, Herba Schizonepetae 1-200, Radix Angelicae Dahuricae 1-100, Camphora 0.1-100, Borneolum Syntheticum 0.1-100, Spina Gleditsiae 1-300, Flos Caryophylli 1-300.
9. according to washout 2 side's medicines of acquired immune deficiency syndrome (AIDS) that claim 1 is treated, it is characterized in that comprising by weight following component: Flos Caryophylli 90, Camphora 5, Borneolum Syntheticum 10, Realgar 80, Rhizoma Acori Graminei 80, Fructus Piperis 50, Oletum Trogopterori 90, Ramulus Cinnamomi 120, Rhizoma Chuanxiong 90, TOUGEYAO 30, Cortex Cinnamomi 150, Radix Aconiti 60, Radix Aconiti Kusnezoffii 60, Fructus Gleditsiae Abnormalis 50, Herba Ephedrae 90, Rhizoma Alpiniae Officinarum 90, Herba Asari 80, Olibanum 50, Myrrha 50, Radix Sophorae Flavescentis 90, Rhizoma Smilacis Glabrae 90, brave zhang 90, Rhizoma Osmundae 90, Cortex Magnoliae Officinalis 90, Rhizoma Atractylodis 90, Rhizoma Curcumae Longae 80, Rhizoma Pinelliae 90, Rhizoma Arisaematis 90, Radix Saposhnikoviae 90, Herba Schizonepetae 90, larval moult 60, the Radix Angelicae Dahuricae 90, Pheretima 90, Bombyx Batryticatus 80, the Radix Aucklandiae 90, Fructus Citri 90, Styrax 100, Radix Et Rhizoma Rhei 100, Radix Aconiti Lateralis Preparata 100, Fructus Arctii 100, Helwingia himalaica 90, Herba Ainsliaea Albotomentosae 90, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 60, Rhizoma Paridis 80, Radix Dipsaci 100, Radix Angelicae Sinensis 100.
10. according to the medicine of acquired immune deficiency syndrome (AIDS) that claim 9 is treated, it is characterized in that comprising by weight following component: Flos Caryophylli 1-300, Camphora 1-200, Borneolum Syntheticum 1-100, Realgar 1-200, Rhizoma Acori Graminei 1-200, Fructus Piperis 1-300, Oletum Trogopterori 1-100, Ramulus Cinnamomi 1-500, Rhizoma Chuanxiong 1-300, TOUGEYAO 1-300, Cortex Cinnamomi 1-500, Radix Aconiti 1-300, Radix Aconiti Kusnezoffii 1-300, Fructus Gleditsiae Abnormalis 1-350, Herba Ephedrae 1-500, Rhizoma Alpiniae Officinarum 1-500, Herba Asari 1-300, Olibanum 1-300, Myrrha 1-100, Radix Sophorae Flavescentis 1-300, Rhizoma Smilacis Glabrae 1-100, tiger zhang 1-200, Rhizoma Osmundae 1-200, Cortex Magnoliae Officinalis 1-500, Rhizoma Atractylodis 1-300, Rhizoma Curcumae Longae 1-400, Rhizoma Pinelliae 1-300, Rhizoma Arisaematis 1-300, Radix Saposhnikoviae 1-400, Herba Schizonepetae 1-300, larval moult 1-300, Radix Angelicae Dahuricae 1-300, Pheretima 1-300, Bombyx Batryticatus 1-300, Radix Aucklandiae 1-400, Fructus Citri 1-400, Styrax 1-500, Radix Et Rhizoma Rhei 1-400, Radix Aconiti Lateralis Preparata 1-400, Fructus Arctii 1-400, Helwingia himalaica 1-300, Herba Ainsliaea Albotomentosae 1-300, Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 1-300, Rhizoma Paridis 1-200, Radix Dipsaci 1-300, Radix Angelicae Sinensis 1-400.
CN2010101469530A 2010-04-09 2010-04-15 Medicament for treating acquired immune deficiency syndrome (AIDS) Pending CN102210837A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2010101469530A CN102210837A (en) 2010-04-09 2010-04-15 Medicament for treating acquired immune deficiency syndrome (AIDS)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201010142665.8 2010-04-09
CN201010142665 2010-04-09
CN2010101469530A CN102210837A (en) 2010-04-09 2010-04-15 Medicament for treating acquired immune deficiency syndrome (AIDS)

Publications (1)

Publication Number Publication Date
CN102210837A true CN102210837A (en) 2011-10-12

Family

ID=44742521

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010101469530A Pending CN102210837A (en) 2010-04-09 2010-04-15 Medicament for treating acquired immune deficiency syndrome (AIDS)

Country Status (1)

Country Link
CN (1) CN102210837A (en)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102552437A (en) * 2012-01-16 2012-07-11 李泽琳 Chinese medicinal composition for treating acquired immune deficiency syndrome and preparation method thereof
CN102614467A (en) * 2012-04-19 2012-08-01 钟波 Traditional Chinese medical composition for treatment of acquired immunodeficiency syndrome and preparation method and application thereof
CN102845665A (en) * 2012-07-27 2013-01-02 安徽四海食品有限公司 Health-care lyophilized powder containing polygonatum sibiricum polysaccharide
CN103316071A (en) * 2013-07-10 2013-09-25 吴中区胥口精益生物医药研究所 Anti-AIDS traditional Chinese medicine essence and extraction process thereof
CN103505593A (en) * 2013-01-09 2014-01-15 王向飞 Chinese medicinal herb formula for removing necrotic tissue and promoting tissue regeneration
CN103505582A (en) * 2013-01-09 2014-01-15 王向飞 Formula of Chinese herbal medicine for treating burn
WO2014032541A1 (en) * 2012-08-27 2014-03-06 Zhang Lin Chinese medicinal preparation for treating aids and preparation method thereof
CN103768251A (en) * 2014-02-24 2014-05-07 侯显夫 Medicine for killing virus in blood cells and improving human antibody immunity
CN104096165A (en) * 2014-06-27 2014-10-15 桂林浩新科技服务有限公司 Herbal cuisine for curing AIDS
WO2016019684A1 (en) * 2014-08-07 2016-02-11 富力 Applications of phillyrin/phillygenin composition in preparing drugs or health care products for relieving and/or treating viral diseases
CN105770431A (en) * 2016-05-17 2016-07-20 唐天东 Traditional Chinese medicine composition for treating AIDS and preparation method thereof
CN106818805A (en) * 2016-12-27 2017-06-13 东莞市联洲知识产权运营管理有限公司 A kind of natural acetylcholinesteraseinhibitors inhibitors and its pesticidal applications
CN107809916A (en) * 2015-06-26 2018-03-16 维塔尔奈克斯特有限责任公司 For treating underfed composition and method
WO2019119018A1 (en) * 2017-12-20 2019-06-27 Vc Tm Pty Ltd A clear skin supplement and medicinal composition for acne
CN112190604A (en) * 2020-09-27 2021-01-08 内蒙古大唐药业股份有限公司 Fresh treatment method of radix isatidis medicinal material
CN114246876A (en) * 2022-01-20 2022-03-29 西北大学 Application of sennoside A in preparation of preparation for resisting pseudomonas aeruginosa infection

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102552437A (en) * 2012-01-16 2012-07-11 李泽琳 Chinese medicinal composition for treating acquired immune deficiency syndrome and preparation method thereof
CN102552437B (en) * 2012-01-16 2013-12-11 李泽琳 Chinese medicinal composition for treating acquired immune deficiency syndrome and preparation method thereof
CN102614467A (en) * 2012-04-19 2012-08-01 钟波 Traditional Chinese medical composition for treatment of acquired immunodeficiency syndrome and preparation method and application thereof
CN102845665A (en) * 2012-07-27 2013-01-02 安徽四海食品有限公司 Health-care lyophilized powder containing polygonatum sibiricum polysaccharide
WO2014032541A1 (en) * 2012-08-27 2014-03-06 Zhang Lin Chinese medicinal preparation for treating aids and preparation method thereof
CN103505582B (en) * 2013-01-09 2015-05-13 王向飞 Formula of Chinese herbal medicine for treating burn
CN103505593A (en) * 2013-01-09 2014-01-15 王向飞 Chinese medicinal herb formula for removing necrotic tissue and promoting tissue regeneration
CN103505582A (en) * 2013-01-09 2014-01-15 王向飞 Formula of Chinese herbal medicine for treating burn
CN103505593B (en) * 2013-01-09 2015-05-13 王向飞 Chinese medicinal herb formula for removing necrotic tissue and promoting tissue regeneration
CN103316071A (en) * 2013-07-10 2013-09-25 吴中区胥口精益生物医药研究所 Anti-AIDS traditional Chinese medicine essence and extraction process thereof
CN103768251A (en) * 2014-02-24 2014-05-07 侯显夫 Medicine for killing virus in blood cells and improving human antibody immunity
CN103768251B (en) * 2014-02-24 2016-06-01 侯显夫 A kind of medicine killed virus in blood cell, improve human antibody's immunizing power
CN104096165A (en) * 2014-06-27 2014-10-15 桂林浩新科技服务有限公司 Herbal cuisine for curing AIDS
WO2016019684A1 (en) * 2014-08-07 2016-02-11 富力 Applications of phillyrin/phillygenin composition in preparing drugs or health care products for relieving and/or treating viral diseases
JP2017523191A (en) * 2014-08-07 2017-08-17 富力 Application of fililine / filigenin composition in the preparation of drugs or health care products for the reduction and / or treatment of viral diseases, and drugs or health care products for the treatment of viral diseases
RU2655616C1 (en) * 2014-08-07 2018-05-29 Ли ФУ Application of phillyrin/phillygenin composition when preparing a medicament or medical product for the relief and/or treatment of viral diseases and medicament or medical product for treatment of viral diseases
US10286002B2 (en) 2014-08-07 2019-05-14 Li Fu Application of a phillyrin/phillygeninin composition in preparing a medicine or health care product for alleviating or/and treating viral diseases, and medicine or health care product for treating viral diseases
US10881679B2 (en) 2014-08-07 2021-01-05 Li Fu Application of a phillyrin/phillygeninin composition in preparing a medicine or health care product for alleviating or/and treating viral diseases, and medicine or health care product for treating viral diseases
US11419915B2 (en) 2015-06-25 2022-08-23 Vitalnext B.V. Compositions and methods for the treatment of malnutrition
CN107809916A (en) * 2015-06-26 2018-03-16 维塔尔奈克斯特有限责任公司 For treating underfed composition and method
CN105770431A (en) * 2016-05-17 2016-07-20 唐天东 Traditional Chinese medicine composition for treating AIDS and preparation method thereof
CN106818805A (en) * 2016-12-27 2017-06-13 东莞市联洲知识产权运营管理有限公司 A kind of natural acetylcholinesteraseinhibitors inhibitors and its pesticidal applications
WO2019119018A1 (en) * 2017-12-20 2019-06-27 Vc Tm Pty Ltd A clear skin supplement and medicinal composition for acne
US11311595B2 (en) 2017-12-20 2022-04-26 Vc Tm Pty Ltd Clear skin supplement and medicinal composition for acne
CN112190604A (en) * 2020-09-27 2021-01-08 内蒙古大唐药业股份有限公司 Fresh treatment method of radix isatidis medicinal material
CN114246876A (en) * 2022-01-20 2022-03-29 西北大学 Application of sennoside A in preparation of preparation for resisting pseudomonas aeruginosa infection
CN114246876B (en) * 2022-01-20 2024-02-27 西北大学 Application of sennoside A in preparation of preparation for resisting pseudomonas aeruginosa infection

Similar Documents

Publication Publication Date Title
CN102210837A (en) Medicament for treating acquired immune deficiency syndrome (AIDS)
CN101612360B (en) Medicine for treating hepatitis, hepatocirrhosis and liver cancer
CN102178804B (en) Chinese medicinal composition for treating perianal eczema and preparation method thereof
Fatima et al. Dandelion: Phytochemistry and clinical potential
CN108853404A (en) A kind of compound Chinese medicinal preparation and preparation method thereof for treating skin and mucous membrane disease
CN102784363A (en) Traditional Chinese medicine composition for treating pancreatic cancer and preparation method thereof
CN102579701B (en) Compound dandelion decoction
CN101879297B (en) Prostate recovery capsules of Chinese medicinal compound preparation, preparation process and application thereof
CN101284107B (en) Medicine for curing cancers and preparation method thereof
CN102552682A (en) Medicine for treating diabetes
CN104815037A (en) Drug for treating rheumatism accumulated toxin type chronic eczema and preparation method of drug
CN105267906A (en) Compound chocolate Chinese herbal composition for treating and improving menstrual syndrome of females
CN106237247A (en) A kind of Chinese medicine composition treating gynecological inflammation
CN103736017A (en) Traditional Chinese medicine composition for treating intercostal neuralgia and preparation method of traditional Chinese medicine composition
US11123388B2 (en) Composition for preventing and treating inflammatory bowel disease
CN104825905A (en) Traditional Chinese medicine preparation for treating blood transfusion reaction and method for manufacturing traditional Chinese medicine preparation
CN103948728A (en) Pharmaceutical composition after chronic nasosinusitis endoscopic sinus surgery
CN103860977B (en) A kind of pharmaceutical composition for the treatment of dermatitis
CN104998034A (en) Chinese herbal medicine combination drug treating livestock respiratory diseases and preparation method thereof
CN109771567A (en) A kind of formula of Chinese herbal medicine supporting vital QI and dispersing blood stasis toxin expelling tumour
CN104971294A (en) Traditional Chinese medicine composition for preventing and treating cattle pneumonia and orally-taken preparation
CN104306832A (en) Chinese herba preparation for treating viral myocarditis and preparing method thereof
CN104689101A (en) Traditional Chinese medicine preparation for treating latent glomerulonephritis and preparation method thereof
CN103623192B (en) Medicine being used for the treatment of pig blue-ear disease and preparation method thereof
CN102188681B (en) Traditional Chinese drug composition for treating pelvic inflammatory disease, preparation method, application thereof

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20111012