CN105267906A - Compound chocolate Chinese herbal composition for treating and improving menstrual syndrome of females - Google Patents

Compound chocolate Chinese herbal composition for treating and improving menstrual syndrome of females Download PDF

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CN105267906A
CN105267906A CN201410327480.2A CN201410327480A CN105267906A CN 105267906 A CN105267906 A CN 105267906A CN 201410327480 A CN201410327480 A CN 201410327480A CN 105267906 A CN105267906 A CN 105267906A
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chinese medicine
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chocolate
traditional chinese
syndrome
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郑建荣
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Abstract

The invention provides a compound chocolate Chinese herbal composition for treating and improving menstrual syndrome of females. The composition comprises cocoa powder, sugar, skim milk, plant oil, salt, carrageenan, natural flavor, Chinese angelica, folium artemisiae argyi, Ligusticum wallichii, achyranthes root, cinnamon, peach seed, corydalis tuber, tree peony bark, Chinese herbaceous peony, flying squirrel feces, safflower, betel nut, balloonflower root, fennel, Poria cocos, wrinkled giant hyssop, magnolia cortex, atractylodes rhizome, perilla, dried orange peel, dahurian angelica root, yeast, ginger, cape jasmine, nutgrass galingale rhizome, licorice, ginseng, combined spicebush, divaricate saposhnikovia root, bitter organe, astragalus, etc. After scientific concentration, the above-mentioned components are combined according to demands of the pathological degree of menorrhalgia syndrome of females and pharmacological characteristics to form a compound Chinese herbal composition for treating menstrual menorrhalgia syndrome and a compound Chinese herbal composition for treating myoma of uterus; and the two compound Chinese herbal compositions have different efficacy and are then mixed with a cocoa chocolate powder composition so as to compose the special compound chocolate Chinese herbal composition or health care food composition capable of treating and improving a variety of uncomfortable symptoms caused by the menstrual syndrome.

Description

Treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition
[technical field]
Treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, relate to chocolate draft Traditional Chinese medicine compound composition, be specifically related to treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, one is used cocoa chocolate powder and is had treatment, improve women physiological period and menstrual period health produce the draft of various pain, Traditional Chinese medicine compound composition formula, to arrange in pairs or groups with medical knowledge characteristic according to its pharmacology and mix, be applicable in improvement, outer American-European personage, and Young Female or adult female acceptable draft Chinese medicine eating mouth feel, and treat simultaneously, improve, before prevention women physiological period and menstrual period syndromes, in, physical function imbalance between the later stage, the various pain produced and uncomfortable disease, special chocolate draft Traditional Chinese medicine compound composition or functional health, health food or new Chinese patent drug.
[background technology]
Degree according to medical institutes survey result display female pathology pain can than headache, stomachache more pain; Every 3 people of women have 2 people to endure dysmenorrhoea puzzlement to the fullest extent, have 6 one-tenth women to think that dysmenorrhoea has a strong impact on the work of attending class; Survey result shows, 68% women has the puzzlement of dysmenorrhoea, and 64% surmounts headache has a stomachache with 40%, has the women of 57% to want dysmenorrhoea to drive out of the life of oneself most, also have the women more than 64% to think, the daily life that dysmenorrhoea has badly influenced them is worked and rested, is attended class or work; According to the display of dysmenorrhoea large survey data, the women up to 78% understands the vexed pain of belly, angor, and the women of 51% is in a bad mood the phenomenon of low tide or irritability during physiology, and women is when the physiology phase in display, and psychology is also greatly affected.
China and foreign countries physician is for gynaecological problem, the syndrome of physiology phase imbalance is inquired into, can be described as quite rigorous, according to the intrinsic determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of Chinese medicine, pathology machine turns observation, cause women physiological period and menstrual period syndrome, the problem concluded is a lot, cause the physiology phase and the uncomfortable reason of syndrome pain in menstrual period also quite a lot of, the primary pathogenic event of 85% is: abnormal Changes in weather, wrongful diet, love are drunk Ice or trimmed the cold air in sky, improper living habit, very large to the injury of health, be the key factor causing estrogen to be lacked of proper care; And when estrogen and corpus luteum hormone nervous system disorder state, can cause autonomic nerve entanglement and physiology phase and menstrual period syndrome, blood circulation, thermoregulation are influenced, produce dysmenorrhoea, headache, dizzy, keck, trick is felt cold, have a sleepless night, depressed, whole body many places pain, is the maximum reason causing physiology phase all malaise symptoms.
Women grows immaturity, or during usual physiology, abnormal living habit and regular ice-cold diet, like wearing dew tripe dress ornament, introduce exopathogenic factor six climate exopathogens (wind, summer-heat, wet, dry, cold, fiery) and be stranded in heat-transformation in uterus, abdominal cavity body, stagnation of phlegm, add imbalance, lose and control, cause QI of the spleen and stomach cannot transporting hormone, affect uterine contraction and autonomic nerve maincenter is interfered, cause female gynecological, uterus or ovary qi depression to blood stasis, functional disorder; According to medical institutes survey result display women physiological period dysmenorrhoea syndrome, be divided into the fourth phase according to its disease degree;
The first phase is GENERAL TYPE dysmenorrhoea: people's percentage accounts for women's number 70%; Clinical symptoms has, dysmenorrhoea, have a headache, have a dizzy spell, vomit, aching pain in waist and back, lower limb are aching and limp, distention and pain in the lower abdomen, distending pain of the breast, emit cold sweat, trick is felt cold, abnormal food appetite;
As caused for hormone is abnormal; Have whole face small pox, the symptom such as dry mouth and tougue, bitter taste in the mouth and dry throat, susceptible to lose temper due to restlessness, breast mammary swelling pain, neurolysis, spirit depressing, asthenia drowsiness, cardiopalmus are felt sick, dysthymic disorder, depressed, short-tempered, sleep disorder, leucorrhea abnormal;
As caused for diseases caused by exogenous pathogenic factor, having advanced menstruation or delaying, measure that few matter is light, row's blood is smooth, amenorrhea clot, hysteromyoma, ovarian cyst, endometriosis, pelvic inflammatory disease, basin peritonitis, oviduct are scorching, causes the problem of life impact.
Second phase is palace muscular tumor dysmenorrhoea: its people's percentage accounts for women's number 15%; Clinical symptoms, except the symptom having GENERAL TYPE dysmenorrhoea all, also has uterus longue tumor and hormonal disorder, and autonomic nerve entanglement syndrome produces; During physiology, endometrium should be peeled off with row's menses, because of various uncertainty, peel off infull when causing women abdominal cavity and endometrium to arrange menses, add and be negligent for the treatment of for a long time, final formation hysteromyoma or chocolate cyst of ovary, slight person's hysteromyoma or chocolate cyst of ovary less than about 5 centimeters, as long as suitably treat, can obtain good therapeutic effect; Hysteromyoma or chocolate cyst of ovary, person more than 5 centimeters, is severe patient, need imposes surgical resection therapy, postoperative suitable to Drug therapy again, just can obtain good therapeutic effect.
The third phase is hemorrhagic hysteromyoma dysmenorrhoea: its people's percentage accounts for women's number 10%; Clinical symptoms, except having all symptoms of front two phase dysmenorrhoea, also has the situation of menstrual blood leakage, water clock.Crack cause: during physiology, endometrium row menses peel off incomplete, form the compressing such as hysteromyoma or chocolate cyst of ovary, cause hemorrhagic dysmenorrhoea; Crack cause mostly is familial heredity, belongs to constitutional dysmenorrhoea more, is more common in adolescence bachelorette, without obvious genitals's pathological changes, has spasmodic contraction pain when menstruation comes; Or cause because of factors such as cervical stenosis, retroversion, menses adverse currents, relevant with body constitution.
The fourth phase is tumor dysmenorrhoea: its people's percentage accounts for women's number 5%; Clinical symptoms except having all symptoms of first three phase dysmenorrhoea, when also having a menstruation, amount is many, matter is light, metrorrhagia, tumor, insomnia etc. situation; Crack cause is Secondary cases dysmenorrhoea, results from pelvis intracavity lesion, easily betides 20 to three ten years old women, or causes because hysteromyoma, uterus adenoma, endometriosis or pelvic cavity infect.
But modern medicine science and technology treatment women dysmenorrhoea, at present can only pain relieving, without basic Therapeutic Method, because modern medicine science and technology is without any advanced armarium healthcare givers at present, can diagnose and learn that women physiological period is lacked of proper care, be weather (wind, summer-heat, wet, dry, cold, fire are detained women part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels gynecological and uterus, form qi depression to blood stasis) and make to practise the factor such as not normal and cause, then be attributed to hormone or lutein offset influence autonomic nerve entanglement generation syndrome more; But at present, the comparatively widely used treatment with hospital, analgesic are Western medicine analgesic on the market.
On hysteromyoma or chocolate cyst of ovary treatment: modern medicine science and technology has surgical resection therapy only, aftertreatment must inject the menolipsis pin more than two months containing Progesterone, coordinate the analgesic of Western medicine anti-inflammation analgesic to take, have that physical weakness is unable, whole body hectic fever, sense of discomfort as climacteric.
The composition of Western medicine analgesic is: Acetaminophen acetaminophen; PseudoephedrineHC pseudoephedrine hydrochloride; Chlorpheniraminemaleate chlorphenamine maleate (because of containing acetyl, phenol, therefore impairing the liver), can be gastrointestinal tract complete rapidly.Within 0.5-2 hour, the highest blood level can be reached.During drug overdose, be absorbed in 4 hours and complete.Mainly discharge with glucuronate and sulfate conjugate glucuronic acid and sulfate conjugate (94%) in urine.About 4% is toxic substance via cytochromeP-450 cytochrome P-450 oxidation ferment metabolism, and liver function just must be understood under normal condition and preferentially be combined with glutathione glutathion and be discharged by urine.
Western medicine analgesic poisoning (Acetaminophenintoxication poisoning by paracetamol); When taking a large amount of acetaminophen acetaminophen for a long time or suddenly, glutathione glutathion storage exhausts, and toxic metabolites may cause hepatic necrosis.Acetaminophen acetaminophen 2-4% discharges with prototype, and the half-life is 1-3 hour, and the half-life of neonate and liver cirrhosis person slightly grows (2.2-5 hour).
Western medicine analgesic contains acetyl, phenol, side effect is meeting impairing the liver, have Western medicine analgesic about 26, the injury that cannot remedy can be caused to liver and blood circulation, even can be fatal, to to seek help treatment to hospital in eight hours, even if the treatment more than eight hours also can cause lifelong infertility etc. to be difficult to the injury of fully recovering; Child overeats and may cause violent sudden and violent property hepatitis, and has the patient of hepatitis to prohibit especially to eat, and hepatitis B person, can make sGOP, sGPT raise a lot, and most Western medicine analgesic all can impairing the liver, and Western medicine is then nearly all impairment of the kidney.
Traditional Chinese medicine therapy method: the traditional Chinese medical science thinks that women is before and after menstruation, affects by pathological changes factor, the hurried change of uterus QI and blood is appointed in punching, runs smooth consequently stagnation of QI and blood may bring about pain or loses and support not Rong Ze pain in moistening.Common several void, real different dysmenorrhoea disease clinically; Qi depression to blood stasis, cold and stagnate, deficient qi and blood, Liver and kidney are weak.
With traditional doctor dialectical and with Gexia Zhuyu Tang, SHAOFU ZHUYN DECOCTION, holy more soup, adjust the opinions such as liver soup to control it, because the different Time of Administration of disease is long, only have the effect that take stopgap measures, form the factor of wind and cold, damp disease without thorough releasing at all; The Chinese medicine SIWU TANG composition medicament generally taken, just more fierce, SIWU TANG is applicable to the people of iron deficiency matter Anemia, as enriching blood, iron supplement matter uses, find that there is hysteromyoma according to modern medicine or chocolate cyst of ovary patient drinks SIWU TANG quasi drugs, muscular tumor or cyst will be made to accelerate to grow up and more worsen, before when thus using SIWU TANG quasi drugs, first must inquire doctor, take again after inspecting health.
With regard to Chinese medicine essence, the mouthfeel that non-hardship is both puckery and strange unpleasant taste, and the mechanical reflection that color muddiness is felt sick, centering, outer personage and modern Young Female or adult female, be nothing but a kind of beating deep down with regard to unacceptable article, be difficult to the thing of swallowing especially; Also causing would rather pain or take Western medicine analgesic, does not also attempt the main cause of eatable Chinese medicines easily.
With acupuncture, herbal fomentation bag or Chinese medicine health-care medicated diet, the warm part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, cold removing be wet, only dysmenorrhoea, and this method can only be releived and be induced sweat, cannot remove intrauterine cold, damp disease because of; Just want to reach blood circulation promoting and blood stasis dispelling, the curative effect of antalgic is limited.
The network poll reference of netting and carrying out is adjusted according to the citation online city of Bo Shite, as Fig. 1 statistical table, count the ratio of women's dysmenorrhoea, wherein all bitterly can account for 23% each menstrual period, frequent pain account for 30%, occasionally just pain account for 40%, the female ratio not having this to perplex completely only has 7%, and this problem has puzzlement to a certain degree to most women as seen.
According to citation network poll reference, as Fig. 2 statistical table, what method can be taked ease the pain when dysmenorrhoea? at most can final election two.Wherein answer comprises and drinks beverage, such as: nigecose, longan tea, hot cocoa equal proportion are the highest, account for 38%; Then the second place that ratio is very nearly the same is had a rest, and what thing does not account for 37%; Then be sequentially eat chocolate 33%, drink warm water 26%, eat analgesic 20%, hot compress 14% etc.Can finding out that women is many to releive pain by adjusting the mode of diet, effectively not treating food or medicine.
In sum, modern medicine science and technology is respectively have its necessity that need break through in the medical skill for the treatment of women physiological period dysmenorrhoea syndrome; In view of this, be necessary in fact to develop Chinese herbal medicine characteristic in conjunction with food, creation can replace containing Western medicine analgesic, effectively, quickly alleviating pain, mouthfeel good, have no side effect, must can not reach the method dispelled extrinsic factor and be detained by long-term taking, to treat the problem of women physiological period dysmenorrhoea syndrome, so prevention hysteromyoma and chocolate cyst of ovary produce special functional health care, health food or medicine.
[summary of the invention]
The present invention treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, system provides a kind of cocoa chocolate powder and draft Chinese Medicine and Clavicular, use its pharmacology and medical knowledge characteristic, during being exclusively used in before, during and after treatment, improvement, prevention women physiological period and menstrual period syndromes, physical function is lacked of proper care, the various pain produced and the special chocolate draft Traditional Chinese medicine compound composition of uncomfortable disease; The apolegamy of the present composition, create according to medicine thing new drug that method is referred to as, use its pharmacology, medical knowledge property combination forms, meet new compound composition, the new compound curative effect of recognizing genus, for the discovery of innovation, the theory of continuity, hold disposition, attitude, guiding that medicine is potential, on the basis of the intrinsic theory of Chinese medicine, treatment classification, pathology turn to coordinate with pharmacology machine to be controlled altogether, improves traditional medical mode.
Adopt simple and easy therapy for oral administration, improve therapeutic efficiency, be applicable to the mechanical printing improving the both puckery mouthfeel of the non-hardship of domestic and abroad personage's centering medicine and unpleasant taste of Chinese medicine further, to meet domestic and abroad personage, and be applicable to Young Female or the acceptable mouthfeel of adult female, treat simultaneously, improve, prevent women physiological period and menstrual period syndrome early, middle, late stage lack of proper care, the first phase GENERAL TYPE dysmenorrhoea produced and second phase hysteromyoma dysmenorrhoea syndrome disease, the diseases such as the various pain that health produces are uncomfortable; Treatment, improve backfisch or ripe female, during physiology phase and menstrual period, because of suitably prevention and treating, Uterine lesion is caused to produce muscular tumor or chocolate cyst of ovary, reduce and carry out excision and operation risk, pancake Medical Consumption, make actual benefit be attributed to other source of disease masses.
Refer to Fig. 3 and embodiment table 1, for treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, disease statistical table before the treatment of tested embodiment 52 example, shown in women physiological period and menstrual period syndrome disease pathology, divide fourth phase different syndromes degree and disease number ratio table thereof, clinical symptoms distribution ratio situation.
Cause women physiological period and reason that menstrual period, syndrome disease caused, for abnormal Changes in weather, like wearing with the women that likes to be beautiful and reveal tripe dress ornament, introduce diseases caused by exogenous pathogenic factor, exopathogenic factor six climate exopathogens (wind, summer-heat, wet, dry, cold, fiery) are stranded in heat-transformation in uterus and abdominal cavity body, inflammation, add imbalance, lose and control, cause QI of the spleen and stomach cannot transporting, cause hormonal disorder, lose one's temper;
Secondly, the inherent autologous factor of abnormal living habit or genetic factor, ice-cold food is eaten with regular, wind and cold and clammy, scorching enter taste, or be stranded in heat-transformation in uterus and abdominal cavity body, inflammation, add imbalance, lose and control, cause QI of the spleen and stomach cannot transporting, hormonal disorder, cause and do the entanglement of habit time, do not have enough sleep, very large on physiological period impact; Affect uterine contraction and autonomic nerve maincenter is interfered, cause causing female gynecological, uterus or ovary qi depression to blood stasis functional disorder, cause women's first phase GENERAL TYPE dysmenorrhoea of 70%; And 15% second phase hysteromyoma type dysmenorrhoea; And 10% third phase hemorrhagic hysteromyoma type dysmenorrhoea; And 5% fourth phase tumorous type dysmenorrhoea; The fourth phase in various degree the physiology phase or menstrual period pain syndrome disease, affect female life quality.
The present invention is this according to the intrinsic theoretical determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of Chinese medicine, treatment, improve women physiological period and menstrual period syndrome, in will being applicable to simultaneously, outer or American-European personage and modern young women or the receptible mouthfeel of adult female and abnormal smells from the patient, coordinate monarch, minister according to its pharmacology, help, make machine turn principle, medication treatment, improvement machine turn, and set forth as follows:
1. adopt cocoa chocolate powder compositions to be combined with herbal compound Chinese medicine composition, improve and take mouthfeel and abnormal smells from the patient; 2. strengthen dispelling the exopathogen be stranded in taste, body of uterus, improve hormonal disorder; 3. strengthen the gas of spleen soil, remove exopathogen delay heat-transformation, cause QI of the spleen and stomach cannot transporting, hormonal disorder; 4. strengthen warm uterus, blood circulation promoting and blood stasis dispelling, help uterus to eliminate clot, endometrium can completely be peeled off, and slows down and removing muscular tumor hypertrophy chance; 5. by the monarch drug of blood circulation promoting and blood stasis dispelling, introduce uterus by taste, subduction qi depression to blood stasis cause dysmenorrhea, various pain, ache, the menstruation syndrome disease problem of clot.
According to the treatment of the present invention's above-mentioned pharmacology machine conversion medicine, effectively can treat, improve, prevent, before, during and after women physiological period and menstrual period syndromes, period lack of proper care, and the special functional Chinese medicine compound of the various sense of discomfort diseases produced is healthy, health food or new Chinese patent drug.
[accompanying drawing explanation]
Fig. 1 draws to adjust net from the online city of Bo Shite, network poll statistics women dysmenorrhoea ration statistics table reference view.
Fig. 2 draws to adjust net from the online city of Bo Shite, what method can be taked to the statistical table reference view that eases the pain during network poll statistics dysmenorrhoea.
Fig. 3 be the present invention treat, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, clinical disease distribution statistics schematic diagram.
Fig. 4 be the present invention treat, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, in draft Traditional Chinese medicine compound composition ferulic acid (Ferulicacid) chromatography analyze TLC figure.
Fig. 5 be the present invention treat, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, ferulic acid (Ferulicacid) 2D-HPLC chromatogram in draft Traditional Chinese medicine compound composition.
Fig. 6 be the present invention treat, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, clinical trial statistical representation be intended to.
[embodiment]
The present invention's treatment, improving the chocolate draft Traditional Chinese medicine compound composition of women physiological period and syndrome in menstrual period, is that utilization cocoa chocolate powder compositions is in conjunction with draft Traditional Chinese medicine compound composition; For improving the non-hardship of domestic and abroad personage's centering medicine and puckery, that the smell is awful, mouthfeel is differential mechanical printing; Domestic and abroad young maiden or all acceptable mouthfeel of adult female and taste can be met, can reach again treatment with prevention women physiological period and menstrual period syndrome, health produce the curative effect of the uncomfortable disease of various pain, be special chocolate draft Traditional Chinese medicine compound composition or dynamopathic health, health-care food composition.
The present invention treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, the enforcement of manufacturing process, each Processing methods link all has the pharmaceutical factory meeting the equipment and facilities that GMP specifies, complete to the process of preparing Chinese medicine from raw material Ji Yuan, purchase, manufacture experimently production, the Chinese crude drug entirely specified according to state-promulgated pharmacopoeia (comprises the different plant-origins of pharmacopeia record, but the medical material of the identical drug effect of tool, or conventional alternative medical material) or Chinese crude drug extract, or the mixture of Chinese crude drug and Chinese crude drug extract;
Preparation method, the preparation of commonly using for any one or extracting process, better with condensing mode, water extraction mode or wine extraction mode be prepared, more preferably, herbal composite of the present invention, obtain with the preparation method of known preparation science concentrated traditional Chinese medicine or known science Chinese medicine (ScientificallyConcentratedTraditionalChineseMedicine), comprise extraction, be separated, concentrated, the operations such as drying, or decoction pieces decocting in water thing preparation method, record according to Chinese medicine voluminous dictionary, meet food and drug administration's prescribed manner preparation, to obtain each pharmaceutical decocting piece decocting in water thing or prepared by the mode such as each pharmaceutical decocting piece water extract or alcoholic extract, after spraying dry granulating, again by the extract of each drying with the science concentrated traditional Chinese medicine powder medical material of special ratios, after add cocoa chocolate powder compositions and mix,
The carrier of its draft Chinese medicine composition; As, oral pattern comprises capsule, ingot sheet, pulvis; For pulvis, general used carrier is corn starch, lubricant or magnesium stearate are basic additive; For oral capsule, use lactose and dried corn starch etc. as effective dilution; If needed, interpolation sweeting agent that can be appropriate, flavoring agent or pigment excipient etc., the carrier that Chinese medicine can accept;
Wherein each pharmaceutical decocting piece decocting in water thing or water extract or alcoholic extract, analyze TLC by chromatography and get the HPLC chromatography collection of illustrative plates that HPLC detects medical material gained, demarcate time and relative time (referring to that peak time of occurrence is except the internal standard substance I.S. time) that each batch of medical material refers to peak appearance, what finger peak must be had to go out as this medical material refers now to foundation; Be exemplified below one of vegetable drug active ingredient measurement Ferulicacid (ferulic acid;
Refer to Fig. 4; For ferulic acid (Ferulicacid) chromatography analyzes TLC figure
TLC:
Refer to Fig. 5; For ferulic acid (Ferulicacid) 2D-HPLC chromatogram
HPLC analysis condition:
The present invention treats, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, a kind of utilization cocoa chocolate powder, and draft Traditional Chinese medicine compound composition formula, arrange in pairs or groups according to both each distinctive pharmacology and medical knowledge characteristic and mix, be exclusively used in treatment, improve, during prevention women physiological period and menstrual period syndromes, the chocolate draft Traditional Chinese medicine compound composition that the uncomfortable disease of the various pain that health produces uses, comprising having: a cocoa chocolate powder compositions, one draft Traditional Chinese medicine compound composition etc., mixing composition chocolate draft Traditional Chinese medicine compound composition,
Wherein, this cocoa chocolate powder compositions, be use cocoa powder body to have pharmacology, ascending, descending, floating, heavy, abnormal smells from the patient, Gui Jing, characteristic, the rationale intrinsic with Chinese medicine, contains in its base derived components: oleic acid, linoleic acid, stearic acid, palmitic acid, protein, vitamin A, vitamin B1, B3, B5, B6, vitamin D, vitamin E, mineral calcium, magnesium, copper, potassium, sodium, ferrum, zinc, cellulose, polyphenol, flavonoid substances, flavonol oligomer-procyanidin and catechin, polymer tannin, phenethylamine, theobromine etc.; Can stabilizing blood sugar, appetite control, easily have satiety, very little to blood sugar influence;
Wherein, linoleic acid can produce GLA and be converted into prostaglandin, can vasodilator, eliminates dysbolismus, and helps insulin work, appetite control; Anadamide in cocoa, phenethylamine can allow be in a cheerful frame of mind, relaxed and joyful, spirit and QI cleaning; Theobromine can make our mental actuity, energy concentrate; Tryptophan in cocoa and magnesium can help the generation of serotonin, make us become calm; Flavonoid reduce cardiovascular disease risk, antioxidation, the several functions characteristic curative effect such as lengthen one's life;
Collocation mixing, treats various women physiological period and pain draft Traditional Chinese medicine compound composition formula in menstrual period, effectively can strengthen the therapeutic effect for the treatment of, improving, prevent women physiological period and the various pain of syndrome in menstrual period, uncomfortable disease; Reach simultaneously improve the non-hardship of Chinese medicine and puckery, the smell is awful, mouthfeel is not good, reaches in being applicable to, outer, young maiden or all acceptable mouthfeel of adult female and the sense of taste; And there is treatment, improve women physiological period and menstrual period syndrome, the special dynamopathic cocoa chocolate powder compositions of the various pain that health produces, uncomfortable disease;
This cocoa chocolate powder compositions, for generally known preferred embodiment combination, its content includes: the edible materials such as cocoa powder 5 ~ 15g, sugar 4 ~ 12g, skim milk 3 ~ 8g, vegetable oil 1 ~ 5g, Sal 0.1 ~ 1g, antler glue 0.1 ~ 1g, natural perfume material 0.1 ~ 1g, the cocoa chocolate powder compound of mixing composition 14 ~ 34g; Do various local flavor according to actual demand, different collocation is done in mouthfeel combination.
Wherein, this draft Traditional Chinese medicine compound composition, be use herbaceous plant Chinese medicine to have pharmacology, ascending, descending, floating, heavy, abnormal smells from the patient, Gui Jing, characteristic, the rationale intrinsic with Chinese medicine, content of the present invention is coordinated to tell pharmacology monarch, minister, help, four large machines are turned, be used for the treatment of, improve, prevent women physiological period and menstrual period syndrome, the various uncomfortable antalgesic that health produces, draft Traditional Chinese medicine compound composition formula; Its pharmacology monarch, minister, help, make and clinical treatment medication implement application method, as follows:
(1) strengthen dispelling exopathogen medication: dispel and be stranded in taste, intrauterine exopathogen, reduce female gynecological and hormonal disorder, uterus or ovary qi depression to blood stasis functional disorder, cause clot, endometrium is peeled off entirely, endometriosis, muscular tumor hypertrophy and menstruation syndrome disease;
(2) strengthen the gas medication of spleen soil: remove exopathogen and be detained heat-transformation and cause QI of the spleen and stomach cannot transporting hormonal disorder, affect uterine contraction and autonomic nerve maincenter be interfered cause have a sleepless night, depressed, emotion low tide, irritability and menstruation syndrome disease etc.;
(3) strengthen warm uterus, cold relieving gas, blood circulation promoting and blood stasis dispelling medication: help uterus to eliminate clot, endometrium can completely be peeled off, slow down and remove muscular tumor hypertrophy chance, strengthening gynecological dai channel function, removes menstruation syndrome disease;
(4) principal agent of blood circulation promoting and blood stasis dispelling is introduced uterus medication by taste: strengthen dispelling cold, warm uterus, subduction qi depression to blood stasis causes the menstruation syndrome disease of dysmenorrhea, clot; During reaching treatment, improving women physiological period and menstrual period syndromes, the draft Traditional Chinese medicine compound composition of the uncomfortable disease of various pain that health produces;
As the present invention treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition in, this draft Traditional Chinese medicine compound composition, first group of preferred embodiment compositions, be exclusively used in treatment treatment, improve women physiological period and syndrome in menstrual period first phase GENERAL TYPE dysmenorrhoea and second phase hysteromyoma type dysmenorrhoea, the present invention treats, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, its formula content includes: Herba Pogostemonis 0.3 ~ 6g, Pericarpium Citri Reticulatae (Pericarpium Citri tangerinae) 0.3 ~ 10g, the Radix Angelicae Dahuricae 0.3 ~ 10g, Rhizoma Zingiberis Recens 0.3 ~ 5g, Oletum Trogopterori 0.3 ~ 8g, Cortex Magnoliae Officinalis 0.5 ~ 4.5g, Radix Angelicae Sinensis 0.3 ~ 12g, Rhizoma Corydalis 0.3 ~ 10g, Folium Artemisiae Argyi 0.3 ~ 10g, Rhizoma Chuanxiong 0.3 ~ 10g, Radix Achyranthis Bidentatae 0.3 ~ 8g, beautiful Ramulus Cinnamomi 0.3 ~ 10g, Cortex Moutan 0.3 ~ 9g, Folium Perillae 0.3 ~ 6g, Radix Paeoniae 0.3 ~ 10g, Cang Intraoperative 0.5 ~ 4.5g, Semen Persicae 0.3 ~ 12g, yeast (Massa Medicata Fermentata, Monas cuspurpureus Went) 0.3 ~ 15g, Flos Carthami 0.3 ~ 6g, Radix Platycodonis 0.3 ~ 4.5g, Fructus Foeniculi 0.3 ~ 3g, Poria 0.3 ~ 6g etc., after the concentrated preparation of science, dosage is made to be 3.5 ~ 18g, for the present invention is exclusively used in treatment, improves draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of women physiological period and syndrome in menstrual period first phase GENERAL TYPE dysmenorrhoea and second phase hysteromyoma type dysmenorrhoea, through clinical test results, effectively can reach more than 90% treatment, improve analgesic effect.
As the present invention treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition in, this draft Traditional Chinese medicine compound composition, second group of preferred embodiment compositions, be exclusively used in treatment treatment, improve women physiological period and syndrome in menstrual period second phase hysteromyoma type dysmenorrhoea, the present invention treats, improve women physiological period and menstrual period syndrome the draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition, its formula content includes: Radix Angelicae Sinensis 0.3 ~ 12g, Radix Ginseng 0.3 ~ 15g, Radix Astragali 0.3 ~ 15g, Rhizoma Chuanxiong 0.3 ~ 10g, Fructus Aurantii 0.3 ~ 9g, beautiful osmanthus 0.3 ~ 10g, Fructus Gardeniae 0.3 ~ 10g, Rhizoma Corydalis 0.3 ~ 10g, Radix Saposhnikoviae 0.3 ~ 10g, Radix Paeoniae 0.3 ~ 10g, Radix Platycodonis 0.3 ~ 4.5g, Folium Perillae 0.3 ~ 6g, the Radix Angelicae Dahuricae 0.3 ~ 10g, the Radix Linderae 0.3 ~ 10g, yeast (Massa Medicata Fermentata, Monas cuspurpureus Went) 0.3 ~ 15g, Rhizoma Zingiberis Recens 0.3 ~ 5g, Oletum Trogopterori 0.3 ~ 8g, Semen Arecae 0.3 ~ 6g, Cang Intraoperative 0.3 ~ 4.5g, Cortex Magnoliae Officinalis 0.3 ~ 4.5g, Flos Carthami 0.3 ~ 6g, Rhizoma Cyperi 0.3 ~ 10g, Radix Glycyrrhizae 0.3 ~ 12g, the Radix Aucklandiae 0.3 ~ 9g etc., after the concentrated preparation of science, dosage is made to be 3.5 ~ 18g, for the present invention is exclusively used in treatment treatment, improves the draft Chinese medicine compound hysteromyoma compositions of women physiological period and syndrome in menstrual period second phase hysteromyoma type dysmenorrhoea, through clinical test results, effectively can reach more than 85% treatment, improve analgesic effect, more than 65% treat, improve female myoma of uterus atrophy effect with effectively reaching.
As the present invention's treatment, improve women physiological period and menstrual period syndrome the draft Traditional Chinese medicine compound composition of chocolate draft Traditional Chinese medicine compound composition; Coordinate pharmacology, monarch, minister, help, four large machines are turned, and application method is implemented in clinical treatment medication, as:
(1) strengthen dispelling exopathogen medication: quote Cortex Cinnamomi branch, Pericarpium Citri Reticulatae, Folium Perillae, nicotine element enter health and to dispel exopathogen.Quote Radix Angelicae Sinensis, Rhizoma Chuanxiong, peoniflorin, Semen Persicae enter health blood system; Ramulus Cinnamomi, Pericarpium Citri Reticulatae, Folium Perillae, Radix Platycodonis, Radix Saposhnikoviae are dispelled exopathogen; Semen Persicae blood stasis removing blood; Dispel the exopathogen be stranded in taste, body of uterus, reduce female gynecological and hormonal disorder, clot causes in institute, endometrium is peeled off entirely, endometriosis, muscular tumor hypertrophy and menstruation syndrome disease;
(2) the gas medication of spleen soil is strengthened: the gas quoting the Radix Linderae, Fructus Aurantii, Radix Astragali, Poria, Pericarpium Citri Reticulatae, Cortex Cinnamomi branch reinforcement spleen soil; The gas of spleen is introduced uterus or ovary.Oletum Trogopterori, Flos Carthami, Folium Artemisiae Argyi strengthen medicine blood stasis removing blood, remove exopathogen to be detained heat-transformation and to cause QI of the spleen and stomach cannot transporting hormonal disorder, affect uterine contraction and autonomic nerve maincenter be interfered cause have a sleepless night, depressed, emotion is irascible with menstruation syndrome disease;
(3) warm uterus, cold relieving gas, blood circulation promoting and blood stasis dispelling medication is strengthened: quote Pericarpium Citri Reticulatae, Cortex Cinnamomi branch, Herba Pogostemonis, Radix Platycodonis enters gas; Semen Persicae, Cortex Moutan, peoniflorin enter blood, with blood circulation promoting and blood stasis dispelling, therefore energy pain relieving; Radix Angelicae Sinensis, Rhizoma Chuanxiong, peoniflorin, exopathogen of dispelling is detained then heat-transformation, in order to heat clearing away; It is hot and suffocating that the delay of Pericarpium Citri Reticulatae, Poria removal pathogen causes; Fructus Foeniculi, Rhizoma Zingiberis Recens, Cortex Cinnamomi branch, Herba Pogostemonis, Radix Platycodonis, Folium Perillae warming the spleen stomach, outer pathogenic wind of dispelling, cold, moved by QI of the spleen and stomach afterwards and use warm uterus again to uterus, helping uterus to eliminate clot endometrium can completely peel off, and slows down and removes muscular tumor hypertrophy chance, strengthening gynecological dai channel function, removes menstruation syndrome disease;
(4) principal agent of blood circulation promoting and blood stasis dispelling is introduced uterus medication by taste: quote Radix Achyranthis Bidentatae, Rhizoma Corydalis, Folium Artemisiae Argyi draw principal agent and enter uterus or ovary; Introduce public region, the part at genus public region, uterus, dispel cold, warm uterus, subduction qi depression to blood stasis menstruation syndrome disease causing dysmenorrhea, clot etc., there is treatment, improve women physiological period and menstrual period syndrome produce various uncomfortable disease, the draft Traditional Chinese medicine compound composition formula of wherein preferred embodiment;
With this preferred embodiment composite formula, collocation is mixed into dynamopathic cocoa chocolate powder compositions again, composition there is treatment, improve women physiological period and menstrual period syndrome disease, special chocolate draft Traditional Chinese medicine compound composition or dynamopathic chocolate draft Chinese medicine compound health, health-care food composition.
Please refer to such as Fig. 6 and embodiment table 2, clinical trial statistical table, for disclose use the present invention treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, preferred embodiment chocolate draft Traditional Chinese medicine compound composition compound composition, turn and safe-dosaging limits using priciple compatibility according to pathology and pharmacology machine, implement clinical disease treatment preferred embodiment medication measure of merit statistical table;
As Fig. 6 and embodiment table 2, test statistics table, wherein therapeutic effect ratio is higher, and relative therapeutic effect is better; Prove chocolate draft Traditional Chinese medicine compound composition compound composition of the present invention, can within the short time, effectively to improve fast, treatment first phase GENERAL TYPE, with second phase non hemorrhagic muscular tumor type women physiological period and syndrome disease in menstrual period, curative effect achievement brilliance;
By in Fig. 6 and embodiment table 2 effect ratio statistical table, prove that the effect for the treatment of, improving can reach more than 85%; Proof is learnt, cocoa chocolate powder compound, can not change the due function of draft Chinese medicine, curative effect, reaches and changes the edible sense of taste, olfactory sensation, and increase eating mouth feel; More can meet domestic and abroad popular backfisch or ripe female all likes suitable edible, more reaches and has treatment, improvements, the chocolate draft Traditional Chinese medicine compound composition that prevents, special health, health food or new Chinese patent drug compositions;
As Fig. 6 and embodiment table 2, clinical trial statistical table curative effect achievement, provable the present invention treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, except can replacing the analgesic efficacy of Western medicine analgesic, can also surmount the therapeutic effect that Western medicine analgesic reaches basic, and the side-effect problem not having drug residue to be harmful to the health produces.
The present invention's treatment, improve the chocolate draft Traditional Chinese medicine compound composition of women physiological period and syndrome in menstrual period, preferred embodiment formula combination, the former and traditional Chinese medical science concerted application of drugs consumption of its pharmacology base and modern pharmacology study foundation reference, as:
Radix Angelicae Sinensis; For the dry root of umbelliferae angelica (Angelicasinensis (OLIVER) DIELS), sweet in the mouth; Property is put down.Gui Jing: liver, kidney, lung meridian.Function: benefiting blood and regulating blood circulation, energy blood circulation promoting, menstruction regulating and pain relieving, moisturizes laxation.Cure mainly: menoxenia, amenorrhea is suffered from abdominal pain, and lump in the abdomen knot is poly-, metrorrhagia, and blood deficiency pain is dizzy; Dryness of the intestine dyschezia, heavy after bloody dysentery, carbuncle subcutaneous ulcer skin infection, injury from falling down, should use Radix Angelicae Sinensis.
Radix Angelicae Sinensis modern pharmacology research foundation:
1, to the effect of uterine smooth muscle: to the effect of isolated uterine, have excited and suppress uterine leio sarcous element to be volatile oil, excited composition is water solublity or alcohol dissolubility and the insoluble nonvolatile matter of ether.And resist the uterine contraction that pituitrin, histamine, epinephrine and acetylcholine etc. cause.Eumenol is mainly excitement, and heavy dose is sometimes in inhibitory action.
2, to the effect of Uterus in vivo: to the unpregnancy of animals such as anesthesia Canis familiaris L., cat, rabbit etc., early pregnancy, evening, various Uterus in vivo Radix Angelicae Sinensis volatile oil has the effect suppressing Uterus in vivo flesh to the various preparation such as Radix Angelicae Sinensis decoct, tincture, petroleum ether immersion, infusion pregnant and puerperal.
3, anti thrombotic action: Radix Angelicae Sinensis and sodium ferulate thereof have obvious anti thrombotic action.Rat experiment Radix Angelicae Sinensis can make thrombosis dry weight show to reduce, and thrombosis growth rate comparatively matched group declines.
4, antitumor action: each polysaccharide sample has inhibitory action to a certain degree to the tumor strain such as rat implantation tumor EC, Hep, S180, Lewis, B16, and its inhibition rate of tumor growth can reach 39%, and side effect is less, and can long-term prescription.
Rhizoma Chuanxiong; For the dry rhizome of samphire Rhizoma Chuanxiong (LigusticumchuanxiongHort. [L.wal-lichiiauct.nonFranch.]).Acrid in the mouth, warm in nature.Gui Jing: liver, gallbladder, pericardium channel.Function: blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping.Cure mainly: menoxenia, amenorrhea dysmenorrhea, the stagnant raw meat pain of the stasis of blood in puerperal, lump in the abdomen lump, pain in chest and hypochondrium, has a headache dizzy, anemofrigid-damp arthralgia, traumatic injury, ulcer sores.
Rhizoma Chuanxiong modern pharmacology research foundation:
1, on platelet aggregation: the impact of thrombosis and blood viscosity, ligustrazine extends the platelet aggregation time of ADP induction in vitro, has depolymerisation to the platelet of having assembled.It may be balance by regulating between TXA2/PGI2 that ligustrazine affects platelet function and thrombosis, ligustrazine suppresses the synthesis of TXA2, finds in Platelet-rich plasm, and the platelet aggregation that after adding ligustrazine, TXA2 causes is shown to be suppressed.
2, to the effect of smooth muscle: 10% aqueous solution of Rhizoma Chuanxiong extractum, to Pregnant Rabbits isolated uterine, can stimulate uterus of becoming pregnant during trace, make its tension force increase, and shrinks and strengthens, become contracture eventually; A large amount of then instead make metroparalysis and shrink stopping.Rhizoma Chuanxiong extractum can suppress isolated rabbit or small intestine of guinea pig in a small amount, and intestinal contraction then can be made in a large number to stop completely.
3, the effect of human peripheral blood pipe and blood pressure: Rhizoma Chuanxiong total alkaloids and ligustrazine can make anesthetized dog vascular resistance decline, makes brain, femoral artery and lower extremity blood flow amount increase.Chuanxiong bioalkali, phenol part and ligustrazine can suppress potassium chloride and epinephrine to the contraction of the in vitro thoracic aorta strips of rabbit.Rhizoma Chuanxiong extractum, infusion, ethanol infusion, alcohol leaching liquid and alkaloid, to anesthetized animals such as dog, cat, rabbits, show and lasting hypotensive effect no matter im or iv all has.
Folium Artemisiae Argyi; For the leaf of Compositae Compositae plant Chinese mugwort ArtemisiaargyiLevl.etVant.; Acrid in the mouth; Bitter; Warm in nature.Gui Jing: return liver, spleen, kidney channel; Function: warming the meridian for stopping bleeding, dispersing cold for relieving pain, removing dampness to relieve itching.Cure mainly: spit blood, epistaxis, painstaking blood, has blood in stool, and has blood in stool, metrorrhagia, gestation hemorrhage, menoxenia, dysmenorrhea, frequent fetal movement, trusted subordinate's cold type of pain, chronic dysentery of having loose bowels, cramp caused by acute vomiting and diarrhea, leukorrhagia, eczema, scabies, hemorrhoid, carbuncle and ulcer.
Folium Artemisiae Argyi modern pharmacology research foundation:
1, anastalsis: Folium Artemisiae Argyi infusion has promotion Blood coagulation to rabbit gavage, but also have think the anastalsis of Folium Artemisiae Argyi fail confirm.Folium Artemisiae Argyi is commonly use hemorrhage, the normal parch to black use of warming the meridian for stopping bleeding, pharmacological evaluation preliminary proof clinically: after Folium Artemisiae Argyi charcoal processing, anastalsis strengthens.
2, to the effect in gastrointestinal tract and uterus: Folium Artemisiae Argyi decoct can excited rabbit isolated uterine, produces tetanic contraction.Rough extractum also has appreciable stimulating action to guinea pig in vitro uterus.Artemisia indica infusion has inhibitory action to isolated rabbit intestinal when a large amount of.
3, to Cardiovascular System: Artemisia indica infusion has inhibitory action to isolated frog heart when a large amount of.From the Tauremizin (being a kind of Sesquiterpene) that Crimean Radix Artemisia ordosicae Artemisiataurica separates, all its contractility can be strengthened to isolated frog heart, the cat heart and the cat heart in place, to the cat heart also energy decreased heart rate, coronary flow is increased, has the effect of adrenomimetic drug.
4, anti-allergic effects: Oleum Folium Artemisiae Argyi 0.5ml/kg gavage, has antagonism to the anaphylactic shock guinea-pigs that ovalbumin causes, and can reduce mortality rate.
5, obviously can shorten the hemorrhage and doubtful blood time, Oleum Folium Artemisiae Argyi has antagonism to multiple allergic asthma, have significantly relieving asthma, Antitussive and Expectorant Effect, its antiasthmatic effect is close with isoproterenol.Experiment in vitro proves, Oleum Folium Artemisiae Argyi all has inhibitory action in various degree to the pneumonia coccobacillus, diphtheria corynebacterium, Diplococcus pneumoniae, staphylococcus aureus and multiple pathomycete; In addition, also inhibitory action is had to adenovirus, rhinovirus, herpus vivus, influenza virus, mumps virus etc.Excitation is had to uterine smooth muscle
Cocoa; The seed of Sterculiaceae Sterculiaceae dicotyledon; The pungent sweetness and bitterness of nature and flavor is puckery.Gui Jing: heart channel, large intestine channel.Alleviate emotion, reinforcement memory, help cardiovascular, energy enhancing immunity, slow down aging.
Cocoa; Modern pharmacology research foundation:
1, in chocolate, fatty 1/3 form is glyceryl stearate (satisfied fatty acid) and olein (unsaturated fatty acid).And compared with other satisfied fatty acid, stearic acid can't cause LDL-C in blood (LDL-cholesterol) concentration to rise.The relatively a large amount of dark chocolate of picked-up and cocoa seem to improve serum LDL-cholesterol concentration; Some research even finds, it can reduce its concentration.Regularly edible a small amount of dark chocolate can reduce heart attack probability.The research undertaken by Stockholm Karolinska institute finds (being published in the internal medicine journal of in JIUYUE, 2009), and the dead probability of cardiac of at least eating twice or thrice chocolate each week reduces 2/3 compared with not eating the cardiac of chocolate.
2, secondary fiber can reduce blood pressure by controlling body weight, and it can also by the angiotensinⅡ suppressing acetylcholine to suppress hyperpietic.Acetylcholine is by suppressing angiotensinⅠ to be converted into strong vasoconstrictor nerve, and angiotensinⅡ improves blood flow and blood pressure.
3, chocolate can alleviate emotion, for focusing one's attention on, strengthening memory and improve intelligence and have effect, helpful cardiovascular effect, can enhancing immunity, have certain effect to slow down aging.
Cortex Cinnamomi branch; For canella Cortex Cinnamomi (CinnamomumcassiaBLUME) and the twig belonging to class edge plant together thereof.Pungent; Sweet; Gui Jing: warm in nature, bladder, the heart, lung meridian.Ramulus Cinnamomi function: warming the meridian and promoting blood circulation, diaphoresis expelling pathogenic factors from muscles.Cure mainly: exterior syndrome due to wind-cold, anemogenous headache, apoplexy spontaneous perspiration, cheiropodagra Xie wind, amenorrhea lump in the abdomen.
Cortex Cinnamomi function: mend the gate of vitality mutually fiery, warming the kidney to invigorate YANG, tonify deficiency labor, removing blood stasis with potent drugs blood, tonneau amenorrhea.Cure mainly: Shen Han syndrome of aversion to cold lasting day and night with cold limbs, asthenia cold abdominalgia, has loose bowels, colic of cold type renal mass, chills and pain of the waist and kness, migratory arthralgia joint contracture, abdominal mass pain in puerperal abdomen.
Cortex Cinnamomi, branch modern pharmacology research foundation:
1, refrigeration function: cinnamic aldehyde (cinnamaldehyde) makes cutaneous vasodilation, has refrigeration function
2, spasmolytic effect: have and suppress nervus centralis effect.
3, for the impact of digestive system: restraining water logging stomach initiation ulcer to rat has inhibitory action, promotes bile secretion.
4, antibacterial action: have inhibitory action to pathogenicity filamentous bacteria.
5, stomach invigorating and carminative: take orally and can make stomach invigorating and carminative.Also have obvious fungicidal action, once application treats tinea capitis containing the mixture of 1.5% Oleum Cinnamomi and 0.5% thymol.Cinnamic aldehyde and Fortificar can cause frog foot web film vasodilation and rabbit leukocyte to increase.
6, intestinal tube excitation: Oleum Cinnamomi is oral to rabbit, can promote bowel movement, makes intestinal tube excited.Having same purpose to isolated rabbit intestinal tube, is ancients' warming the spleen and stomach, except good explanation has been done in cold long-pending saying.
7, the effect of stimulating the menstrual flow: a large amount of Oleum Cinnamomi can cause metremia, the display effect of stimulating the menstrual flow, this fetal abortion effect being ancient book on Chinese herbal medicine is said provides an experimental basis
8, to the effect of blood: Cortex Cinnamomi has the effect of the rat platelet aggregation obviously suppressing ADP induction, in vitro tests display Cortex Cinnamomi water decoction and solution and methanol part have stronger anticoagulation
9, sedation: the cinnamic aldehyde contained in Cortex Cinnamomi has obvious sedation to mice, show as spontaneous activity to reduce, what antagonism methamphetamine (Methamphetamine) produced crosses multi-activity, and mice pressure anal spine swashs or the method for lumbar injection acetic acid observation writhing motion proves that it has analgesic activity
Semen Persicae; For rosaceous plant Fructus Persicae (Prunuspersica (L) BATSCH) and belong to together near line plant drying and ripening, remove endocarp kernel.Bitter sweet; Flat; Nontoxic; Gui Jing: the heart, liver, large intestine, lung, spleen channel.Function: blood stasis removing and clots absorbing, moisturizes laxation.Cure mainly: amenorrhea, lump in the abdomen, calentura blood-retention, migratory arthralgia, malaria, traumatic injury, swelling and pain due to blood stasis, the dry constipation of blood.
Semen Persicae modern pharmacology research foundation:
1, blood stasis dispelling blood effect: water decoction-alcohol sedimentation liquid can make isolated rabbit ear vein vascular flow increase, and has vasodilator effect.To anesthetized dog intra-arterial injection, femoral artery blood flow can be increased and reduce vascular resistance, having direct dilating effect to blood vessel wall.Have and suppress blood coagulation and haemolysis.Semen Persicae extract 50mg/ml, in splenic artery, administration can make blood flow in anesthetized rat liver microcirculation accelerate, and has some improvement to liver surface microcirculation.
2, anti-allergic effects: Semen Persicae water extract can suppress the generation of skin-sensitizing antibodies in mice serum and house mouse spleen hemolytic cell, the pigment seepage discharge of oral PCA reaction (passive cutaneous anaphylaxis, PCA) that the antiserum that mice contains skin hypersensitivity antibody can be suppressed to cause of its ethanol extraction.
Flos Carthami; For the dry petal of feverfew Flos Carthami (CarthamustinctoriusLINN).Acrid in the mouth; Warm in nature.Gui Jing: enter the heart, spleen, stomach warp.Function: invigorating blood circulation can be through; Stasis-dispelling and pain-killing.Cure mainly: amenorrhea, dysmenorrhea, postpartum stagnation is suffered from abdominal pain, and the pained lump in the abdomen of dysfunction of the urinary bladder, traumatic injury, arthralgia, middle windage yaw is completed, macule.
Flos Carthami modern pharmacology research foundation:
1, suppress key role: Flos Carthami decoct low dose can make Bufo siccus isolated heart and rabbit heart in vivo slightly excited, make heart beating strong, amplitude strengthens; Heavy dose then has inhibitory action to heart, makes decreased heart rate, and myocardial contraction weakens, and cardiac output reduces.
2, the blood coagulation resisting function of Carthamus yellow: Carthamus yellow has very aobvious landing and suppresses the Platelet Aggregation in Rabbits effect of ADP induction, and has obvious depolymerisation to the platelet that ADP has assembled.
3, hypotensive effect: Flos Carthami decoct, Carthamus yellow have rapid depressurization effect in various degree to anesthetized cat or dog, mean blood pressure declines 20 minutes about Hg, continues to recover after about 30 minutes.
4, to the effect in uterus: the isolated uterine of Flos Carthami decoct to mice, Cavia porcellus, rabbit and dog has excitation.Anesthetized animal experiment shows, also there is excitation in the in place uterus of decoct iv to mice, cat and dog.
Fructus Foeniculi; For the dry mature fruit of San shape section Zhi Wu Huai perfume (or spice) (FoeniculumvulgareMILL.).Acrid in the mouth; Warm in nature.Gui Jing: liver, kidney bladder, stomach warp.Function: dry kidney stomach warming, dispersing cold for relieving pain, warm public region, mends the gate of vitality.Curing mainly: colic of cold type, renal cold lower abdominal pain, preventing or arresting vomiting in tune, dry beriberi caused by pathogenic damp, snakebite, dyspepsia, is fragrant stomachic.
Fructus Foeniculi modern pharmacology research foundation:
1, on the impact of gastrointestinal motility: Fructus Foeniculi has facilitation to rabbit in body enterokinesia.Anethole has excitation to mice intestine in vitro, and concentration increases, and occurs relexation, and lax intestinal tube is also reactionless to acetylcholine.Relexation is about 25% of papaverine, and anethole is about 28%, and fenchone about 3%, anisaldehyde is about 4%, and limonene is about 2%, and cineole is about 1%.Volatile oil acts on guinea pig ileum longitudinal muscle muscle bundle, and strengthen it and shrink, EC50 is 6-7 μ g/ml.
2, to the effect of liver: extract rat to part liver, to Fructus Foeniculi volatile oil 10 days, hepatic tissue regeneration increases, and the WEIGHT RATIO Comparative group of liver increases.
3, gonadotropic Effect: Mus great and mighty or powerful was to Fructus Foeniculi acetone extractum 15 days, and testis, deferential total protein content reduce, and the smart wing and prostatic total protein then obviously increase, acidity, the alkaline phosphatase activities of these organs reduce; Female rat acetone extractum 10 days, occur that intravaginal keratinization and sexual cycle promote, mammary gland, fallopian tube, endometrium, myometrium weight increase, and think that Fructus Foeniculi has estrogen-like effects.
Rhizoma Zingiberis Recens; For the dry rhizome of zingiber (ZingiberofficinaleROSC.).Pungent, heat.Gui Jing: return spleen, stomach, the heart, lung meridian.Function: warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, warming the lung to resolve fluid-retention.Cure mainly: Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.
Rhizoma Zingiberis Recens modern pharmacology research foundation:
1, analgesic activity: each group mice respectively ginger essential oil, pethidine and etc. capacity tween saline, after administration, tool shows analgesic activity, and ginger essential oil has the analgesic activity shown.
2, to platelet aggregation effect: for ADP, (platelet aggregation of the rabbit of 10umol/L induction, 6-zingiberol is only in higher concentrations just in slight inhibitory action.But to the platelet aggregation that arachidonic acid (160umol/L) brings out, 6-zingiberol has obvious inhibitory action.
3, antibacterial, protozoacide effect: the water leaching agent of Rhizoma Zingiberis Recens all has inhibitory action in various degree to Bacillus typhi, vibrio cholera, violet tinea bacterium and trichomonas vaginitis.
The Radix Angelicae Dahuricae; For the samphire Radix Angelicae Dahuricae (AngelicadahuricaBENTH.etHOOK.var.pai-chiKIMURA, HAYATAetYEN).Acrid in the mouth; Warm in nature; Gui Jing: return lung, spleen, stomach warp.Function: the pain of head and face disease, dispels the wind, detumescence, evacuation of pus, pain relieving.Cure mainly: headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Radix Angelicae Dahuricae modern pharmacology research foundation:
1, spasmolysis: the Radix Angelicae Dahuricae has obvious spasmolysis containing bergapton, xanthotoxin, isoimperatorin second to rabbit ileum.Isoimperatorin can also increase the contractility of rabbit uterus and the tonicity of Lumbricus flesh.Scopoletin has spasmolysis to estrogen or barium chloride at body or isolated rat uterus spasm.
2, antipyretic effect: the hot animal model of height caused in White Rabbit back with peptone subcutaneous injection, the 1g Radix Angelicae Dahuricae or Radix angelicae dahuricae decoct 15g, have obvious refrigeration function.
3, to cardiovascular effect: the isoimperatorin contained by this product and baelfruit element have the effect of blood pressure lowering to cat.The copolymer of isoimperatorin and N-vinylpyrrolidone can make cat arterial pressure reduce, and can also reduce the contractility of isolated frog heart.
4, antitumaous effect: isoimperatorin and there is the cytotoxicity to Hela cell from angelicin.
Folium Perillae: be the dried leaves (or band twig) of labiate wrinkle Folium Perillae (Perillafrutesens. (L.) BRITT.var.crispa (THUNB.) HAND-MAZZ.).Acrid in the mouth; Warm in nature.Gui Jing: return lung, spleen, stomach warp.Function: dispersing wind-cold, promoting the circulation of QI to alleviate the stagnation in middle-JIAO, expectorant profit lung, surely shouts and breathes heavily, antiabortive, solving toxin of fish and crab.Caulis Perillae is specially in regulating the flow of vital energy.Cure mainly: anemogenous headache, heating, distension and fullness of the chest and abdomen, cough, asthma, nausea is got along well, and acute mastitis swells and ache, and incised wound is hemorrhage, crab poisoning.
Folium Perillae modern pharmacology research foundation:
1, refrigeration function: the rabbit generated heat with Folium Perillae decoct and preserved material 2g/kg oral administration typhoid fever polyvalent vaccine, has faint refrigeration function.
2, to the effect of blood clotting: Folium Perillae Aqueous extracts is to family's rabbit ear table intravenous injection, and can shorten blood clotting time, blood plasma recalcification time and activated partial thromboplastin time, Folium Perillae intrinsic coagulation system has facilitation.
3, promote enterokinesia: isolated Perillaketone in Folium Perillae, have promote enterokinesia effect to rat, enteral prods is moved and accelerates, expanding about flesh to intestinal has stimulation.
4, sedation: in Folium Perillae, isolated perillaldehyde, Stigmasterol, Dillapiole all have sedation, can extend the length of one's sleep of the rat that phenobarbital reduces, Folium Perillae water decoction 1:20 concentration, has inhibitory action to viral ECHO11 strain.
Poria; For the dry sclerotia of Polyporaceae plant Poria (Poriacocos (Schw.) Wolf).Sweet in the mouth, light, property is put down.Gui Jing: enter the heart, spleen, lung meridian.Function: eliminating dampness and diuresis, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Cure mainly: dysuria, edema distension, phlegm retention cough with dyspnea, nausea and vomiting, have loose bowels, pass out semen, stranguria with turbid discharge, palpitation with fear, forgetful.
Poria modern pharmacology research foundation:
1, on the impact of digestive system: Poria has direct relexation to family's rabbits infestines, there is preventive effect to the ulcer that rat pylorus ligation is formed, and can gastric acid be fallen.Separately there is significant protective effect to Liver Damage in Rats caused by CCl4, gpt activity is obviously reduced, prevents hepatic necrosis.
2, antitumor action: the main component in Poria is pachyman (Pachyman), can reach 96.88% to the suppression ratio of S180 sarcoma.
Pericarpium Citri Reticulatae (Pericarpium Citri tangerinae); For rutaceae Fructus Citri sinensis (Citrussinensis (L.) OSBECK) and the fresh or dry outer peel belonging to kindred plant mellow fruit matter together.Bitter, pungent, temperature.Gui Jing: return lung, spleen channel.Function: in tune, regulates the flow of vital energy, and leads expectorant, diuretic; Rule all kinds of diseases and ailments, all get the merit of its dampness of regulating the flow of vital energy.Cure mainly: the therapeutic method to keep the adverse QI flowing downwards helps digestion, preventing or arresting vomiting is inverse, and reduce phlegm brokenly knot, and emesis rushes down, diuresis.
Pericarpium Citri Reticulatae modern pharmacology research foundation:
1, to the effect of digestive system: volatile oil contained by Pericarpium Citri Reticulatae, gentle stimulation is had to gastrointestinal tract, can the secretion of facilitating digestion liquid, get rid of pneumatosis in intestinal tube, show the effectiveness of fragrant stomach invigorating and the wind dispelling therapeutic method to keep the adverse QI flowing downwards.
2, to the effect of cardiovascular system: Pericarpium Citri Reticulatae decoct, ethanol extract can be excited myocardium, occur on the contrary suppressing when dosage is excessive.Blood vessel can be made to produce slight contraction, rapid raising blood pressure.Pectin in Pericarpium Citri Reticulatae also has certain preventive effect to the arteriosclerosis that high fat diet causes.
3, to the effect of respiratory system: the irritant passive phlegm-dispelling functions of volatile oil contained by Pericarpium Citri Reticulatae, makes sputum easily bring up.Pericarpium Citri Reticulatae decoct has faint dilating effect to bronchus.The relievining asthma of its ethanol extract is tired higher.
Herba Pogostemonis; For the dry stem and leaf of labiate Herba Pogostemonis (AgastacherugosaFISCH.etMEY.O.KUNTZE) Counterfeit species.Acrid in the mouth; Slightly warm in nature.Gui Jing: return lung, spleen, stomach warp.Function: fast gas and in, stomach reinforcing gas, dampness removing except wind, appetizing preventing or arresting vomiting.Cure mainly: dyspepsia, cholera is told inverse, dysentery, sore throat, cough, halitosis, cold syndrome of the stomach and cause vomiting and diarrhoea, abdomen or uncomfortable in chest etc.
Herba Pogostemonis modern pharmacology research foundation:
1, bacteriostasis Herba Pogostemonis ketoboidies has obvious inhibitory action to funguses such as white bead-containing bacteria, Cryptococcus histolyticus, bread molds for a long time, also has certain inhibitory action to antibacterials such as α-hemolytic streptococcuss.The growth of the fresh juice of Herba Pogostemonis leaf to staphylococcus aureus, Staphylococcus albus and bacillus subtilis also has fixed inhibitory action.Its fresh juice drips the acute experimental Cavia porcellus otitis externa that ear (4 droplets/time, every day 3 times) can treat caused by Staphylococcus aureus.Pogostone can suppress the length of the mycetes such as penicillium, can be used for the anticorrosion of oral liquid.
2, Ca2+ overloading anti-effect Herba Pogostemonis water extract shrinks the isolated guinea pig colic band that high potassium causes obvious suppression, and show that it has calcium antagonism, 3 × 10-4g/ml, suppression ratio is 17%, during 30 × 10-4g/ml, and suppression ratio reaches 91%.Effective ingredient is patchouli alcohol, and parameter for antagonist (PA2) value of its calcium antagonism is 5.95, IC50 is 4.7 × 10-5mol/L.Patchouli alcohol, to the contraction of the rat aortic article that Ca2+ causes, also with the verapamil phase heart, has relying property of dosage antagonism.
Yeast; For Massa Medicata Fermentata, Monas cuspurpureus Went, the herbal leaven of medicated beer through fermenting, Aspergillaceae fungus monascus parpureus Went colonizes in the Monas cuspurpureus Went on Semen oryzae sativae.Sweet; Temperature; Nontoxic.Gui Jing: enter liver, spleen, large intestine channel.Function: blood circulation promoting and blood stasis dispelling, strengthening the spleen to promote digestion.Cure mainly: main eating accumulation, distension and fullness in the abdomen, red white dysentery, prolonged lochia, traumatic injury.
Yeast modern pharmacology research foundation:
Separable to coenzyme Q10 after yeast (Massa Medicata Fermentata, Monas cuspurpureus Went, medicated beer) fermentation, coenzyme Q10 has another name called coenzyme, is the startup agent of cellular metabolism and Cellular respiration, can improves mitochondrial respiratory function, accelerating oxidation phosphorylation reaction.Itself is again the native oxidant that cell self produces, and can suppress mitochondrial peroxidating, has the function of protection biofilm structure integrity.There is non-specific potentiation to immunity, can cytophagous phagocytic rate be improved, increase the generation of antibody, improve T cell function.
Radix Platycodonis; For Campanulaceae Radix Platycodonis (Platycodongrandiflorum (JACQ.) A.DC.) removes the dry root of crust.Bitter in the mouth, pungent; Property is put down.Gui Jing: return lung, stomach warp.Function: sharp chest and diaphragm, warming middle-JIAO.Cure mainly: exogenous cough, laryngopharynx swelling and pain, evacuation of pus of eliminating the phlegm, lung abscess, fullness in the chest costalgia, dysentery, abdominal pain.
Radix Platycodonis modern pharmacology research foundation:
1, to eliminate the phlegm and antitussive effect: anesthetized dog oral this product decoct 1g/kg, can show the secretory volume increasing respiratory mucus, its intensity can compared with ammonium chloride.Also obvious phlegm-dispelling functions is had to anesthetized cat.Mice voluntary activity can be suppressed, extend the length of one's sleep of ciclobarbital soluble.
2, gastric secretion and antiulcer action is suppressed: rough kikyosaponin has suppression rat gastric secretion and anti-peptic ulcer effect when the dosage lower than 1/5 median lethal dose(LD 50).During 100mg/kg dosage, almost can suppress the gastric secretion caused by rat pylorus ligation completely.
3, to the effect of blood circulation: rat with rough kikyosaponin intravenous injection, visible temporary blood pressure drops, decreased heart rate and respiration inhibition.
Radix Achyranthis Bidentatae; For amaranthaceous plant Radix Achyranthis Bidentatae (AchyranthesbidentataBLUME) and the dry root belonging to kindred plant together.Also the name Radix Paeoniae Alba (" medicineization justice ").Bitter in the mouth, acid; Property is put down.Enter liver, kidney channel.Function: dissipating blood stasis blood, detumescence pain, invigorating the liver and kidney, bone and muscle strengthening.Cure mainly: the dysmenorrhea that blood stasis is caused, amenorrhea, lump in the abdomen, and retention of placenta in puerperal, stomachache, and sore throat pain is swollen, traumatic injury, waist kneecap pain, spasm of the limbs flaccidity syndrome and arthralgia syndrome.
Radix Achyranthis Bidentatae modern pharmacology research foundation:
1, on the impact of heart: Radix Achyranthis Bidentatae alcohol extract is to isolated frog heart, and anesthetized cat has certain inhibitory action, and water decoction is more obvious to the effect of Myocardium in Anaesthetized Dogs.
2, on the impact of animal blood pressure: Radix Achyranthis Bidentatae decoct all has of short duration hypotensive effect to anesthetized cat and dog etc., with respiratory stimulant during blood pressure drops, hypotensive effect, also without tachylaxis, infers that its mechanism of action may with the release of histamine, Cardiac depression and to expand peripheral blood vessel relevant.
Radix Paeoniae Alba; For ranunculaceae plant Radix Paeoniae (PaeonialactifloraPALL.=P.albifloraPALL.) removes the dry root of cork.Bitter; Acid; Be slightly cold.Gui Jing: liver; Spleen channel.Function: nourish blood and seek medicine; Relieving spasm to stop pain medicine; Yin fluid astringing liver-pacifying medicinal.Cure mainly: menoxenia; Abdominal pain during menstruation; Metrorrhagia; Spontaneous perspiration; Night sweat; Side of body rib epigastric pain; Limb pain twin; Headache.
Radix Paeoniae Alba modern pharmacology research foundation:
1, spasmolysis: Radix Paeoniae or paeoniflorin have suppression or spasmolysis to smooth muscle, the Spontaneous Contraction of guinea pig in vitro small intestinal can be suppressed, its tension force is reduced, and the contraction of Cavia porcellus that barium chloride causes and Isolated rabbit intestine can be resisted, rat small intestine in vitro caused by acetylcholine is shunk and has no significant effect, but add and show inhibitory action with having after Radix Glycyrrhizae.
2, to protect the liver and Detoxication: Radix Paeoniae Alba extract raises Liver Damage in Rats caused by D-galactosamine and AFB1 and ALT, the gross activity of lactic acid dehydrogenase (SLDH) caused by the latter and isozyme thereof is raised, all has obvious inhibitory action.Radix Paeoniae Alba ethanol extract has certain Degradation to Aspergillus flavus poison rope B1 in vitro.Trivial solution toxic action is had to mice T-2 toxin poisoning.
3, antimutagenic and antitumor action: Radix Paeoniae Alba extract can disturb the enzymatic activity of S9 mixed liquor, and the metabolite inactivation of benzo Wang (BAP) can be made and suppress the mutagenesis of BAP.Gallic acid (GA) and five galloyl glucoses (PGG) can make the metabolite inactivation of BAP, and PGG can suppress the enzymatic activity of S9 mixed liquor.Radix Paeoniae Alba extract can strengthen the antitumor action of ametycin.
Radix Paeoniae Rubra; For ranunculaceae plant river Radix Paeoniae Rubra (PaeoniaveitchiiLYNCH) and the dry root belonging to kindred plant together.Bitter; Be slightly cold; Gui Jing: liver, spleen channel.Function: removing fire from the liver, promoting blood circulation to restore menstrual flow, reducing swelling and alleviating pain.Cure mainly: the stagnant amenorrhea of the stasis of blood, metrorrhagia leukorrhagia, dysentery is suffered from abdominal pain, carbuncle conjunctival congestion, epistaxis.
Radix Paeoniae Rubra modern pharmacology research foundation:
1, anti-thrombosis function: Radix Paeoniae Rubra decoct 15-20g (crude drug)/kg, to rat oral gavage, makes thrombus formation time obviously extend, contraction in length, weight saving; Prothrombin time and KPTT extend, and euglobulin lysis time shortens, and has show inhibitory action to blood clotting.
2, antiplatelet aggregative activity: Radix Paeoniae Rubra extract all has epinephrine, adenosine diphosphate (ADP) (ADP), Trimeresurus (TMVA) and arachidonic acid (AA) induced platelet aggregation in vitro and shows inhibitory action, and platelet adhesion and platelet factor III activity are reduced, in platelet, cAMP content raises.
3, hepatoprotective effect: the DNA synthesis of Radix Paeoniae Rubra injection to Cultured Hepatocytes in vitro has obvious facilitation, has good impact to liver cell regeneration and liver function recovery.Obvious protective effect is had to Liver Damage in Rats caused by D-galactosamine.
Rhizoma Cyperi; This product is the dry rhizome of sedge dried tuber CyperusrotundusL., and pungent micro-hardship is sweet, flat.Return liver; Lung; Spleen; Stomach; Tri-jiao channel warp.Function: resolving depression of regulating the flow of vital energy; Menstruction regulating and pain relieving; Antiabortive.。Cure mainly: distending pain over the hypochondrium; Mammary swelling is educated; Hernia pain; Menoxenia; Gastral cavity abdomen feeling of fullness pain; Belch acid regurgitation, vomiting and nausea; Abdominal pain during menstruation; Bleeding not during menses; Frequent fetal movement.
Rhizoma Cyperi modern pharmacology research foundation:
1, to the effect of cardiovascular system: the reports such as Soviet Union scholar Akperbekova.BA, to frog subcutaneous injection Rhizoma Cyperi water or water one alcohol extract, can make the frog heart stop at systole.During low concentration, to isolated frog heart, and the frog heart in place, Cor Leporis and the cat heart have cardiotonic or decreased heart rate effect.The aqueous solution of Rhizoma Cyperi total alkaloids, glycoside, flavonoid and phenolic compound also has heart tonifying and decreased heart rate effect, and has obvious hypotensive effect.
2, estrogen-like effects: ovariectomized female rats test shows, Rhizoma Cyperi volatile oil has slight estrogenic activity.Volatile oil 0.2ml, interval 6h subcutaneous injection 2 times, the complete keratinization of vagina epithelium after 48 hours; When 0.3ml is administered three times, a lot of leukocyte of anti-appearance in a large amount of keratinocyte, these compositions may belong to proestrogen (ProesTCMLIBagen) class, increased activity after transforming in vivo.This effect of Rhizoma Cyperi is one of Main Basis of its treatment menoxenia.
3, to the effect in uterus: 5% Rhizoma Cyperi fluid extract is to the isolated uterine of the animals such as Cavia porcellus, rabbit, cat and dog, and no matter oneself pregnant or unpregnancy, has inhibitory action, make that its contractility weakens, muscular tension reduces.Its interaction property and angelicin are quite similar, but more weak.
4, antibacterial action: in vitro tests, Rhizoma Cyperi volatile oil has inhibitory action to staphylococcus aureus, invalid to other antibacterials.The bacteriostasis of cyperene I and II is stronger than volatile oil, and also effective to sonne bacillus.Hydrogenation does not affect its antibacterial action.Cyperone is then completely invalid.Rhizoma Cyperi extract also has inhibitory action to some fungus.
Rhizoma Corydalis; For papaveraceae plant corydalis (CorydalisyanhusuoW.T.WANG) and the dry tuber belonging to kindred plant together.Bitter sweet; Flat; Nontoxic.Gui Jing: liver, stomach, the heart, lung, spleen channel.Function: promoting blood circulation to remove blood stasis, promoting the circulation of QI pain relieving, enriching blood and lisieux respire key medicine.Cure mainly: all pains of breast abdomen, menoxenia, metrorrhagia drenches dew, and puerperal, stagnant blood stagnated, and lump in the abdomen flutters damage.
Rhizoma Corydalis modern pharmacology research foundation:
1. analgesic activity: prove by electricity irritation mousetail method, Rhizoma Corydalis powder, Corydaline all have the analgesic activity shown.
2. the relexation of pair muscle: the experiment to rabbit, isolated guinea pig of Diethylaminoethyl tetrahydropalmatine, tetrahydropalmatine shows there is relexation to its muscle.
3. on the impact of cardiovascular system: Rhizoma Corydalis ethanol extract have show expand extrasomatic rabbit heart and the body cat heart coronary vasodilator, reduce coronary resistance and the effect increasing blood flow.The most obvious to anesthetized dog dilating effect coronarius, internal carotid artery takes second place.Also certain dilating effect is had to femoral artery.
Cortex Moutan; For young pilose antler gelsemium section plant Paeonia suffruticosa (PooaeoniasuffruticosaANDR.) and belong to the dry root bark that kindred plant rip cutting divests woody part together.Arduous; Cool, be slightly cold.Gui Jing: the heart, liver, kidney, lung meridian.Function: heat clearing away removing fire from the liver, removing heat from blood, and blood, repercussive.Cure mainly: typhoid fever pyretic toxicity sends out speckle, epistaxis, spit blood, have blood in stool, amenorrhea, hectic fever due to YIN-deficiency consumptive fever, carbuncle, skin ulcer in incised wound.
Cortex Moutan modern pharmacology research foundation:
1., on cardiovascular impact: Cortex Moutan can increase coronary flow to the anesthetized dog heart, reduce cardiac output, reduce the effect of left room work done.Have obvious protective effect to expeirmental myocardial ischemia, and the persistent period is longer, reduces myocardial oxygen consumption simultaneously.Also certain antihypertensive effect is there is to kidney-type hypertension dog and rat with paeonol 0.5-1.0g/kg.
2. anticoagulation: external human blood platelets to be tested, find that Cortex Moutan water extract and Radix Paeoniae phenol all can suppress platelet arachidonic acid to produce thromboxane A2, and then anticoagulant, this is the result owing to suppressing from arachidonic acid to the reaction of the Cycloxygenase of prostate H2.Cortex Moutan methanolic extract has the effect suppressing experimental thrombosis caused by endotoxin.
Cervical cancer cell all has inhibitory action.Paeonol has certain inhibitory action to the metabolism of benzopyrene in hepatomicrosome, has antiearly pregnancy effect, has diuresis.
Oletum Trogopterori; For the dry feces of vertebrates flying squirrel section trogopterus xanthipes (trogopterusxanthipesMILNS-EDWARDS).Bitter in the mouth; Sweet; Warm in nature; Gui Jing: liver, spleen channel.Function: promoting the circulation of blood pain relieving.Cure mainly: all diseases of trusted subordinate's vim and vigour, women's amenorrhea, postnatal blood stasis is had a pain, and insect bite is hindered.
Oletum Trogopterori modern pharmacology research foundation:
1. on the impact of cardiovascular system: Oletum Trogopterori 20mg/kg femoral artery injects and makes anesthesia Canine femoral artery blood flow increase, and vascular resistance reduces.Oletum Trogopterori Aqueous extracts 200ug/ml can dramatically the oxygen consumption reducing rat neonatal rat Cardiac Cells In Vitro.
2. anticoagulation: Oletum Trogopterori Aqueous extracts 2.0g/ml has reinforcement fibrin dissolution.
3. the effect in pair uterus: Oletum Trogopterori water decoction is that short time tension force improves to isolated rabbit uterus, and recover normal after a few minutes, part suppresses phenomenon after occurring, and little to frequency, amplitude influences.In vitro tests proves, Oletum Trogopterori has inhibitory action in various degree to tubercule bacillus and various skin fungus; Also has the effect alleviating smooth muscle spasm, clinically also once for angina pectoris.
Cortex Magnoliae Officinalis; For Magnoliacea plant Cortex Magnoliae Officinalis (MagnoliaofficinalsREHDERetWILSON) and the dry bark belonging to kindred plant together.Bitter; Pungent; Warm in nature.Gui Jing: spleen, stomach, large intestine channel.Function: warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, loose full, dampness, repercussive, removing mass, stomach reinforcing intestinal.Cure mainly: distension and fullness of the chest and abdomen is had a pain, vomiting, dysentery, breathes with cough.
Cortex Magnoliae Officinalis modern pharmacology research foundation:
1. hypotensive activity: cat (body weight 2.1-2.7kg)/only, intravenous injection magnocurarine 3mg/kg, blood pressure drops is about 20mmHg, continues about 10 minutes.
2. antitumor action: Cortex Magnoliae Officinalis methanolic extract honokiol has obvious inhibitory action to the mouse skin tumor that carcinogenic test the second stage of in body causes.
3. the inhibitory action of platelet aggregation: Magnolol and Honokiol suppresses gathering and the ATP release of the rabbit platelet rich plasma of collagen and arachidonic acid-induction, and washed platelet aggregation is more obviously more suppressed than the gathering of platelet rich plasma.
Semen Arecae; For the dry mature skin of babassu Semen Arecae (ArecacatechuLINN.).Acrid in the mouth; Slightly warm in nature.Gui Jing: spleen, stomach, large and small intestinal warp.Function: therapeutic method to keep the adverse QI flowing downwards alleviating distention in middle-JIAO, row water, logical intestine and small intestine.Cure mainly: painful abdominal mass is swollen expectorant diaphragm, edema beriberi, dysuria, cholera.
Semen Arecae modern pharmacology research foundation:
1. central action: in cat intravenous injection, this product arecoline (arecoline) occurs that various self-discipline is through symptom, has and stimulates brain stem sample body, the effect of activation cortex E.E.G.
2. smooth muscle effect: arecoline and pilocarpine (pilovarpine) have close effect, makes intestinal tube smooth muscle brute force shrink, increases intestinal tube tonicity and mobility, shrink the effect of pupil smooth muscle.
Radix Ginseng; For Araliaceae Radix Ginseng (pANAXGINSENGc.a.meyer) removes the dry root of fibrous root.Bitter in the mouth, micro-hardship; Slightly warm in nature.Gui Jing: kidney channel, lung, spleen channel.Function: strongly invigorating primordial QI, tonifying YIN blood, promotes the production of body fluid, and tonifying the lung is calmed the nerves.Cure mainly: impairment caused by overstrain is deficient, heart tonifying emergency treatment of collapse, lack of appetite Ni is idle, dyspnea with shortness of breath, cold extremities sweating, and stool lingering diarrhea, palpitates with fear forgetful, dizziness and headache, sexual impotence, and frequent micturition, quenches one's thirst, woman uterine bleeding, and children's's intermittent infantile convulsion and prolonged deficiency are not multiple, the card of all qi-blood-body fluid deficiencies.
Radix Ginseng modern pharmacology research foundation:
1. the effect of pair hemopoietic function: Radix Ginseng or the hemopoietic function of its extract to bone marrow have protection and stimulation, can make normal and anemia animal erythrocyte number, leukocyte count and hemoglobin content increase.Also RBC number, hemoglobin and platelet can be made to increase anemia patient.
2. the effect of pair platelet function: Radix Ginseng has the effect of anticoagulant.To health adult oral red ginseng powder 1.5g on an empty stomach, after clothes, blood drawing in 1 and 3 hour measures platelet aggregation, result is compared with before taking medicine, it has to the platelet aggregation that arachidonic acid, ADP, thrombin and epinephrine etc. bring out the inhibitory action shown, and is also suppressed by the generation of the platelet malonaldehyde of arachidonic acid and thrombin induction simultaneously.Relatively 70% methanolic extract of Radix Ginseng Rubra and Radix Ginseng is in vitro to the inhibitory action of rabbit platelet aggregation.
3. antitumor action: the multiple Saponin contained in Radix Ginseng, ginseng polysaccharide and ginseng essential oil have antitumor action.In Radix Ginseng Rubra, ginsenoside can make cancerous cell break up again, induce and reverse as non-cancerous cells.Stem and leaf of Radix Ginseng total saponins can suppress the speed of growth and the splitting ability of Human Gastric Cancer Cells In Vitro, increases the former content of endocellular sugar, reduces mucopolysaccharide and activity of acid phosphatase in cell, plays certain obstruction Growth of Gastric and the effect of propagation.Flos Ginseng, leaf glycol group Saponin also have certain antitumor action in vitro.Radix Ginseng aerial parts volatile oil composition can make the gastric cancer of In vitro culture and hepatoma carcinoma cell number reduce, growth is suppressed, dead cancer cell count increases.
Radix Astragali; For leguminous plant Inner Mongol Radix Astragali (AstragalusmongholicusBUNGE), film pod Radix Astragali (Amenbranaceus (FISCH.) BUNGE) and the dry root belonging to kindred plant together.Sweet; Temperature.Gui Jing: the heart, lung, spleen, kidney channel.Function: invigorating the spleen and replenishing QI, life strengthening superficial resistance to stop perspiration, granulation promoting, evacuation of pus expelling the toxic substance from the body with tonic, processs by invigorating middle warmer benefit vigour, yang invigorating hemopoietic.Cure mainly: gastroptosis, uterine prolapse, deficiency of vital energy blood prostration, metrorrhagia, proctoptosis.
Radix Astragali modern pharmacology research foundation:
1. cardiovascular system is affected: this product infusion or alcohol extract make rabbits blood pressure show to reduce, its hypotensive effect is not by cutting off both sides cervical region vagus nerve or first using atropine (α-atropine) to dispose impact, and slightly blood vessel is relevant with directly expanding end for its hypotensive effect.
2. intestinal tube is affected: this product infusion has guinea pig rat small intestine in vitro and shows contraction.
3. sexual cycle is affected: this product infusion causes female rat rutting period.
The Radix Aucklandiae; For the dry root of feverfew Radix Aucklandiae (Radix Vladimiriae) (SaussurealappaCLARKE).Acrid in the mouth; Bitter; Warm in nature.Gui Jing: return liver, stomach, intestinal warp.Function: invigorating the spleen and regulating the stomach, dispersing the stagnated live-QI to relieve the stagnation of QI, promoting the circulation of QI to relieve pain.Cure mainly: breast abdomen arteries and veins pain, pain in the hypochondrium, vomiting is had loose bowels, dysentery tenesmus, bladder cold type of pain, hernia.
Radix Aucklandiae modern pharmacology research foundation:
1. pair cardiovascular effect: the volatile oil of Radix Aucklandiae of low concentration and from volatile oil isolated lactone part can suppress the activity of Cavia porcellus and rabbit isolated heart, also have inhibitory action to isolated frog heart.
2. the effect of pair intestinal: Radix Aucklandiae Aqueous extracts, volatile oil and lanceolate on mice rat small intestine in vitro first have slight excitation, and tonicity and rhythmicity obviously reduce subsequently.Antagonism is had to myenteron spasm caused by acetylcholine, histamine and barium chloride.
3. the effect of pair respiratory system: guinea-pig isolated trachea and lung perfusion experiment prove, Radix Aucklandiae Aqueous extracts, alcohol extract, volatile oil and total alkaloids can to antihistamine and acetylcholine to trachea and bronchial spasmolysises.The Ginkgolide Components such as total lactones, constuslactone, dihydrocostulactone contained by volatile oil and the bronchoconstriction effect of going lactone volatile oil all can cause antihistamine, acetylcholine and barium chloride, wherein stronger with dihydrocostulactone effect.
Fructus Gardeniae; For Maguireothamnus speciosus Hu subtree (GardeniajasminoidesELLIS.var.angustifoliaNAKAI) and other belong to the ripe dry fruit of kindred plant together.Bitter; Cold.Gui Jing: the heart, liver, lung, stomach, tri-jiao channel.Function: heat clearing away, pathogenic fire purging, removing heat from blood, can make the thermal buckling of cardiopulmonary descending, go out from urine.Cure mainly: dysphoria and insomnia, jaundice, gonorrhea, thirsty, conjunctival congestion, headache, spits blood, epistaxis, damp and hot yellowish body (infectious hepatitis, serum hepatitis).
Fructus Gardeniae modern pharmacology research foundation:
1. analgesic activity: gardenoside and hydrolyzate genipin thereof have inhibitory action to the mouse writhing motion that lumbar injection acetic acid causes.
2. promote pancreatic secretion effect: gallbladder pancreas intubate research Fructus Gardeniae and the different extract thereof such as Yang Zhizhen are on the impact of large cowardly pancreas flow and enzymatic activity, and Fructus Gardeniae and several extract thereof have obvious sharp pancreas, function of gallbladder promoting and fall pancreatin effect.
3. the protective effect of liver: 1.2.1.ICR rat in advance (before 24 or 48 hours) awards Fructus Gardeniae extract, can prevent the acute severe hepatitis because galactosamine causes.
Radix Saposhnikoviae; For the dry root of umbelliferae Saposhnikovia divaricata (Saposhinkoviadivaricata (TURCZ.) SCHISCHK.) Counterfeit species.Acrid in the mouth; Sweet; Slightly warm in nature.Gui Jing: bladder, lung, spleen, Liver Channel.Function: induce sweat, dispels the wind, and dries, pain relieving.Cure mainly: the headache and dizziness controlling affection of exogenous wind-cold, rachiagia stiffness of the nape, anemofrigid-damp arthralgia, joint is ached, and extremity contraction is anxious, tetanus, dispel the wind and not dry be demulcen in wind medicine.
Radix Saposhnikoviae modern pharmacology research foundation:
Antipyretic, analgesic activity: rabbit triple vaccine (pertussis, diphtheria, tetanus vaccine) is made animal pyrogenicity model.RADIX SAPOSHINOKOVIAE from Northeast decocting liquid 2g/kg, compares with anodynine and normal saline.Radix Saposhnikoviae decocting liquid is antipyretic in 1-2 hour, analgesic activity is obvious.
The Radix Linderae; For the dry root of the canella Radix Linderae (Linderastrychnifolia (SIEB.etZUCC.) F.VILLARS=DaphnidiumstrchnifoliumSIEB.etZUCC.).Pungent; Temperature.Gui Jing: spleen, stomach, liver, kidney, urinary bladder channel.Function: circulation of qi promoting, pain relieving, the kidney warming, cold expelling.Cure mainly: QI rising in reverse order chest and abdomen swelling and pain, dyspepsia does not disappear, and food is told in regurgitation, colic of cold type beriberi, frequent micturition.
Radix Linderae modern pharmacology research foundation:
1. the excitation of volatile oil: time for oral administration, have excited corticocerebral effect, and have promotion to breathe, excited cardiac muscle, accelerates blood circulation, the effect of raising blood pressure and diaphoresis.Local topical makes local vascular dilation, and blood circulation accelerates, and relaxes muscle spasm pain.
2. on gastral impact: the Radix Linderae has the secretion increasing Digestive system to gastrointestinal smooth muscle.
3. anastalsis: experiment in vitro proves, Radix Linderae dry powder can obviously shorten plasma in rabbit recalcification time, promotes blood clotting and good anastalsis.Its Borneolum Syntheticum can diaphoresis, excitement, spasmolytic, anthelmintic etc.
Fructus Aurantii; For rutaceae trifoliate orange Fructus Citri tangerinae (Poncirustrifolia (L.) RAF.), Citrus aurantium Linn. (CitrusaurantiumLINN.) or fragrant circle (C.wilsoniiTANAKA) and the immature fruit belonging to kindred plant together.Hardship, acid; Cold nature.Gui Jing: lung, spleen, liver, stomach, large intestine channel.Function: broken stagnant gas, wide the intestines and stomach, eliminates the phlegm.Cure mainly: the stagnant food stagnation of chest and diaphragm expectorant, vomiting and regurgitation, cholera dysentery, typhoid fever oh, proctoptosis.
Fructus Aurantii modern pharmacology research foundation:
1. the effect of pair tracheal smooth muscle: Neosynephrine has the effect of stronger expansion trachea and bronchus.Anesthetized cat intravenous injection completely to the bronchoconstriction caused by antihistamine, can also have same effect to guinea-pig isolated trachea.
2. antihemagglutination: rat takes composition Nobiletin in Fructus Aurantii, has and suppresses hematoblastic agglutination, have obvious anti-thrombosis function to rat.
3. antitumaous effect: Nobiletin is 3-28 μ g/ml to the median effective dose of nasopharyngeal carcinoma KB cell, in body to Mice Bearing Lewis Lung Cancer and Wa Ke carcinoma 256 also effective.
4. the effect of pair uterine smooth muscle: the uterus flaccidity of Fructus Aurantii Immaturus decoct to unpregnancy and pregnant rabbit isolated uterine, uterus in place and unpregnancy rabbit all has obvious excitation, and the uterine contraction rhythm and pace of moving things can be made to increase.But to mice isolated uterine, no matter pregnant or unpregnancy part plays inhibitory action.
5. the effect of gastrointestinal smooth muscle: Fructus Aurantii Immaturus decoct is inhibitory action to mice intestine in vitro part, and rabbits infestines then all shows suppression.Gastrointestinal motility can be made to shrink the rhythm and pace of moving things increase.
Pu Yellow; For Typhaceae plant typha (TyphaangustifoliaLINN.) and the dry pollen with tree kindred plant.Sweet in the mouth, micro-pungent; Property is put down.Gui Jing: the heart, liver, spleen channel.Function: clots absorbing diuresis is used in life, parch to black is with receiving Grating hemostasis.Cure mainly: life is suffered from abdominal pain through Closed with-Zhi, and postpartum stagnation is had a pain, stranguria with blood, dysuria, traumatic injury, carbuncle.Fry with controlling metrorrhagia, under Tapes, hemorrhage; External treatment wound, eczema.
1, Pollen Typhae main component: common cattail is containing glucose, rhamnose (Rhamnose), xylose (Xylose) and other oligosaccharide (Oligosaccharide).
2, Pu Yellow modern pharmacology research foundation:
(the effect of 1) Dui Palace and intestinal smooth: the in vitro sub-Palace of 50% Pu Yellow injection in Guinea-pigs and rabbit all have excitation at Ti Palace.Low dose makes Regulations Ze Palace contraction slightly increase Strong, and great Ji Liang Time Palace excitation obviously strengthens, in irregular and spastic Shou Shrink.Its mechanism may be shunk relevant with anastalsis with directly increasing sub-Palace.Contained by Pu Yellow, isorhamnetin has spasmolysis to mice intestine in vitro.
(2) Right Xin blood vessel Xi System affect: Pu Yellow extracting solution is significantly increased Guan Veins flow effect to extrasomatic rabbit heart.Also effect is improved to mouse cardiac muscle microcirculation.
(3) on the impact of coagulation process: Pu Yellow can make Rabbit Blood Platelets number increase, Shrink is short for thrombin elementary time, has the effect obviously shortening blood coagulation time.The ripe parch to black of Pu Yellow, can increase anastalsis.Pu Yellow Zhong Yellow ketone compounds (Lo fourth, Quercetin etc.) there is the tannin of anastalsis.
Myrrha; For the resin of olive subject plant Myrrha book (CommiphoramyrrhaENGIER) or kindred plant.Bitter; Flat.Gui Jing: liver, spleen, the heart, kidney channel.Function: loose blood blood stasis removing, subduing swelling and relieving pain.Cure mainly: fall damage, incised wound, muscles and bones, Xin Fu Zhu pain, lump in the abdomen , Jing Closed, ulcer sore pain, anal fistula, diseases of the eye.Inner takes: decoct soup, 3 ~ 10g.
1, Myrrha main component: myrrh resinous 25 ~ 35%, volatile oil 2.5 ~ 9%, natural gum about 57 ~ 65% is moisture and various impurity about 3 ~ 4% in addition.The major part of resin can be dissolved in ether, and insoluble part is containing a and B heerabomyrrholic acid, and soluble part is containing a, B and r myrrholic acid, commiphorinic acid, a and B heerabomyrrhol.Still containing rare myrrh colloid myrrhin, commiferin.Volatile oil is resinophore in atmosphere, containing eugenol, a phenyl methylcarbamate, cumaldehyde, pinene, cinene, limonene, cinnamic aldehyde, heerabolene etc.
2, Myrrha modern pharmacology research foundation:
(1) astriction: Myrrha tincture has astriction to mucosa, oral cavity, the pharynx portion infections Time that bursts can be used in mouth wass; Also can be used for stomach anenterneuria Time with excited enterokinesia.
(2) antiinflammatory, analgesia and antipyretic effect: the multiple congener of Myrrha is all found to have the effects such as antiinflammatory.As the oleoresin ligroin extraction of Myrrha, can obviously suppress inflammation caused by carrageenin and granuloma induced by implantation of cotton pellets, mice also has obvious antipyretic effect.
The present invention's treatment, improve the chocolate draft Traditional Chinese medicine compound composition of women physiological period and syndrome in menstrual period, clinical example is described as follows (only provide partly test data provide reference):
Embodiment 1
Experimenter: so-and-so Miss of Cai, 1967 births, 42 years old, height 165cm, body weight 55kg.
Residence: Taoyuan County Fructus Myricae rubrae town, occupation: working clan, disease: without major disease.
Physiology phase clinical symptoms: be first phase GENERAL TYPE dysmenorrhoea, have distending pain of the breast, have headache, lumbago, dizzy etc.
Treatment improvement mode: through giving the present invention treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, early, in, evening is each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 3.5g: chocolate content 23g wraps), brew when the physiology phase rises pain on the same day and take, pain relieving is improved after taking latter about 25 ~ 30 minutes in first time, no longer have a headache after improvement, not lumbago, not dizzy, emotion is happy, first time takes latter sustainable 6 ~ 7 hours, medicine is taken all without sense of discomfort to evening, menstrual blood volume obviously increases, output, increases, clot output, increases, follow-uply take to second night, without sense of discomfort, i.e. drug withdrawal, give up simultaneously and stay up late and drink cold drink and be accustomed to,
Secondary month: the physiology phase rose the same day, menstrual period were normal, and symptom is improved completely so far.
By above-mentioned experimental result: prove the present invention's treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, effectively improve the dysmenorrhoea symptoms such as distending pain of the breast, dizzy headache, lumbago, can effectively improve GENERAL TYPE menstrual period first phase, menstrual period syndrome disease.
Embodiment 2
Experimenter: Miss Chen, 1992 births, 18 years old, height 163cm, body weight 47kg.
Residence: Xin Zhuan district of Xin Bei city, occupation: student, disease: without major disease.
Physiology phase clinical symptoms: be first phase GENERAL TYPE dysmenorrhoea, distending pain of the breast, headache, lumbago, dizzy, stomachache, trick is felt cold, menstrual period are delayed, have a sleepless night, emotion low tide etc.
Treatment improvement mode: through giving the present invention's treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, early, middle and late each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 3.5g: chocolate content 23g wraps), brew when the physiology phase rises pain on the same day and take, pain relieving is improved after taking latter about 30 ~ 35 minutes in first time, trick is no longer felt cold, emotion is happy, and menstrual blood volume is obviously normal; Continue to take to the 3rd day completely without sense of discomfort;
Secondary month: the physiology phase rose the same day, do not eat ice because being out of patience and drink cold drink, though menstrual period are normal, feel cold without trick, have a headache, dizzy, emotion low tide, the symptom such as irritability improved, still there are menstruation sore waist and aching in the waist and the back, stomachache situation, through taking medicament again 3, improve completely.
By above-mentioned experimental result: prove the present invention's treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, effectively can improve first phase GENERAL TYPE dysmenorrhoea symptom, because eating ice and drinking cold drink, symptoms such as causing trick to feel cold, have a headache, dizzy, menstruation sore waist and aching in the waist and the back, stomachache, emotion low tide are irascible, can effectively improve menstrual period, menstrual period syndrome disease.
Embodiment 3
Experimenter: so-and-so Miss of Liu, 1987 births, 23 years old, height 160cm, body weight 60kg.
Residence: South, Taichung.Occupation: be engaged in outdoor vocational work.Disease: without major disease.
Physiology phase clinical symptoms: be first phase GENERAL TYPE dysmenorrhoea; Often drink cold drink, distending pain of the breast, headache, lumbago, dizzy, stomachache, mammary swelling chest pain, trick feel cold, Hypomenorrhea, menstrual period are delayed, the long pox of whole face, insomnia, depressed, emotion low tide etc.
Treatment improvement mode: through giving the present invention treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, early, in, evening is each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 3.5g: chocolate content 23g wraps), brew when the physiology phase rises pain on the same day and take, pain relieving after taking latter about 30 ~ 35 minutes for the first time, trick is sent out no longer cold, emotion is happy, may persist to take evening second time medicine all do not have sense of discomfort, menstrual blood volume obviously increases output, continue to take to the 3rd day evening, menstrual blood volume is normal, without sense of discomfort.
Secondary month: the physiology phase rose the same day, menstrual period were normal, still have the symptoms such as lumbago, abdomen are vexed, the long small pox of face, after taking medicament again through pain, abdomen is vexed improves completely, the long small pox symptom of face improves more than 80%.
By above-mentioned experimental result: prove the present invention's treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, effectively can improve menstruation distending pain of the breast, headache, lumbago, dizzy, stomachache, mammary swelling, chest pain, trick are felt cold, Hypomenorrhea, menstrual period are delayed, the long small pox of whole face, insomnia, the situation such as depressed, emotion low tide, can effectively improve first phase GENERAL TYPE dysmenorrhoea, menstrual period syndrome disease.
Embodiment 4
Experimenter: so-and-so Miss of Cai, 1983 births, 27 years old, height 158cm, body weight 46kg.
Residence: Xin Zhuan district of Xin Bei city.Occupation: working must work in cold air room.Disease: without major disease.
Physiology phase clinical symptoms: be first phase GENERAL TYPE dysmenorrhoea; Like drinking cold drink, distending pain of the breast, headache, lumbago, dizzy, stomachache, trick feels cold, Hypomenorrhea, clot, amenorrhea, menstrual period are delayed, have a sleepless night, depressed, emotion low tide, irritability etc.
Treatment improvement mode: through giving the present invention treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, early, in, evening is each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4g: chocolate content 24g wraps), brew when the physiology phase rises pain on the same day and take, first time improves pain relieving after 25 ~ 30 minutes after taking, trick is sent out no longer cold, emotion is happy, may persist to take evening second time medicine all do not have sense of discomfort, menstrual blood volume obviously increases, clot output, increases, take to second night, menstrual blood volume is normal, and clot reduces, and turns the red blood of row, take and improved, without sense of discomfort to the 3rd day evening.
Secondary month: the physiology phase rose the same day, menstrual period were normal, without sense of discomfort, still have Hypomenorrhea clot situation, improve completely after taking medicament again.
By above-mentioned experimental result: prove the present invention's treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, effectively can improve Hypomenorrhea clot, Hypomenorrhea, clot, amenorrhea, menstrual period are delayed, situation of having a sleepless night, can effectively improve first phase GENERAL TYPE dysmenorrhoea, menstrual period syndrome disease.
Embodiment 5
Experimenter: wear so-and-so Miss, 1985 births, 25 years old height 158cm, body weight 46kg.
Residence: mountain of papers district of Taibei city.Occupation: pharmacy works.Disease: without major disease.
Physiology phase clinical symptoms: be first phase GENERAL TYPE dysmenorrhoea; Often drink cold drink, distending pain of the breast, dizzy headache, sore waist and aching in the waist and the back, stomachache, trick is felt cold, menstrual period are delayed, have a sleepless night, the long pox of whole face, emotion low tide etc.
Treatment improvement mode: through giving the present invention's treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, early, evening is each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4g: chocolate content 24g wraps), brew when the physiology phase rises pain on the same day and take, pain relieving is improved after taking latter 30 minutes in first time, trick send out no longer cold, emotion is happy, may persist to take second time medicine all do not have sense of discomfort, menstrual blood volume obviously increases; Continue to second night, without sense of discomfort, menstrual blood volume is obviously normal; Continue to take to the 3rd day evening, without sense of discomfort.
Secondary month: the physiology phase rose the same day, menstrual period were normal, still have menstruation soreness of waist situation, improve completely after taking medicament again.
By above-mentioned experimental result: prove the present invention's treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, can effectively improve menstruation sore waist and aching in the waist and the back, effectively can improve first phase GENERAL TYPE syndrome in menstrual period disease.
Embodiment 6
Experimenter: so-and-so Miss of Lee, 1987 births, 23 years old, height 158cm, body weight 52kg; And its sister three people etc.
Residence: Xin Bei city.Occupation: working clan.Disease: with its sister three people etc., all without major disease.
Physiology phase clinical symptoms: be first phase GENERAL TYPE dysmenorrhoea; Often burn the midnight oil and often drink cold drink, each own distending pain of the breast, have headache, lumbago, dizzy, trick is felt cold, emit cold sweat, angina abdominis can be rolled on the ground, Hypomenorrhea, clot, menstrual period are mixed and disorderly, emotion low tide is irascible.
Treatment improvement mode: through giving the present invention treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, early, evening is each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4g: chocolate content 24g wraps), brew when the physiology phase rises pain on the same day and take, pain relieving is improved after 30 ~ 45 minutes after taking in first time, trick is no longer felt cold, emotion is happy, may persist to before taking medicine evening and still have slight lumbago, the slight sense of discomfort of stomachache, menstrual blood volume obviously increases, clot output, increases, continue to take to second night, sense of discomfort alleviates, and menstrual blood volume is normally bright, and clot reduces, continue to take to the 3rd day evening, without sense of discomfort, give up simultaneously and stay up late and drink cold drink and be accustomed to.
Secondary month: the physiology phase rose the same day, menstrual period were normal, and sister three people etc. do not drink cold drink so far, and symptom is improved completely.
By above-mentioned experimental result: prove through giving the present invention's treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, early, wrap evening each one, effectively can improve first phase GENERAL TYPE dysmenorrhoea, distending pain of the breast, have headache, lumbago, the symptom such as dizzy, trick is felt cold, emit cold sweat, angina abdominis can be rolled on the ground, Hypomenorrhea, clot, menstrual period are mixed and disorderly, emotion low tide is irascible, effectively can improve syndrome disease in menstrual period.
Embodiment 7
Experimenter: so-and-so Miss desolate, 1967 births, 43 years old, height 153cm, body weight 50kg.
Residence: Xinzhu City.Occupation: breakfast dealer need get up work early in the morning.Disease: have endometriosis, hysteromyoma disease.
Physiology phase clinical symptoms: be second phase hysteromyoma type dysmenorrhoea; There are distending pain of the breast, headache, lumbago, dizzy, trick is felt cold, emit cold sweat, angina abdominis, Hypomenorrhea, clot, menstrual period are mixed and disorderly, during day of rising, have the symptoms such as blood leakage, water clock.
Treatment improvement mode:
(1) through giving the present invention's treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, early, middle and late each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4g: chocolate content 24g wraps), brew when the physiology phase rises pain on the same day and take, rear about pain relieving after more than 45 minute is taken in first time, after sustainable about 6 hours, pain symptom recurs again, need take help pain relieving again;
(2) reconstruction view gives the present invention's treatment, improve women physiological period and menstrual period syndrome the draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition, early, middle and late each once, take three days continuously, second day first time took rear about pain relieving after more than 30 minute, take three days dysmenorrhoea symptoms nothing completely, the symptoms such as blood leakage, water clock are obviously improved.
Secondary month: discriminant amendment is early, middle and late respectively once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4.5g: chocolate content 25g wraps), take 7 days continuously, the physiology phase rises brewed clothes on time the same day, menstrual period are normal, symptom improves depletion of blood leakage, water clock symptom entirely, and uterine prolapse, hysteromyoma there is no and obviously change phenomenon.
Continuous three months afterwards: cast same medicine, improved syndrome disease and without obvious menstruation water clock in menstrual period, hysteromyoma, endometriosis have clear improvement phenomenon.
By above-mentioned experimental result: prove through giving the present invention's treatment, improve women physiological period and menstrual period syndrome the draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition, effectively can improve second phase hysteromyoma type dysmenorrhoea symptom, effectively can to improve when menstruation comes temporary transient water clock and improve syndrome disease in menstrual period, as long as the proof physiology phase rises, uterus is arranged menses, is peeled off normally, is effectively to help hysteromyoma, endometriosis to shrink.
Embodiment 8
Experimenter: so-and-so Miss of Cai, 1981 births, 29 years old, height 162cm, body weight 50kg.
Residence: Xin Bei city.Occupation: school assiatant.Disease: ovary and uterus chocolate cyst disease.
Physiology phase clinical symptoms: be second phase hysteromyoma type dysmenorrhoea; Fixing monthly edible four things are drunk and are often drunk cold drink; Distending pain of the breast, have headache, lumbago, dizzy, trick is felt cold, emit cold sweat, angina abdominis, Hypomenorrhea, clot, menstrual period are mixed and disorderly, emotion low tide is irascible.
Treatment improvement mode:
(1) through giving the present invention treatment, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of chocolate draft Traditional Chinese medicine compound composition, early, in, evening is each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4g: chocolate content 24g wraps), brew when the physiology phase rises pain on the same day and take, rear about pain relieving after more than 45 minute is taken in first time, but symptom trick is felt cold after continuing about 4.5 hours, emit cold sweat, angina abdominis recurs again, take three days symptoms continuously just to releive completely, after menstrual period, abdominal part also has sense of discomfort, it within continuous three months backward, is all discriminant amendment morning, in, each 4.5g took continuously only to obtain for 7 days and releived evening, if but without meeting pain of taking medicine, therefore advise that she arrives large hospital inspection, just learn as ovary is left, respectively there is chocolate cyst on the right side, 8 centimeters and 14 centimeters,
(2) advise surgical resection therapy, treatment after excision, hospital requirements must injection containing the menolipsis pin two months of Progesterone, take anti-inflammation analgesic, have that physical weakness is unable, whole body hectic fever sense of discomfort as climacteric.
After (3) two months, through giving the present invention's treatment, improve women physiological period and menstrual period syndrome the draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition, early, evening is each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4.5g: chocolate content 25g wraps), gradually recover normal in.
Every other month: the physiology phase rose the same day, menstrual period are normal, and symptom is significantly improved.
By above-mentioned experimental result: prove through casting the present invention's treatment, improve women physiological period and menstrual period syndrome the draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition, effectively can improve second phase hysteromyoma type dysmenorrhoea symptom, though dysmenorrhoea syndrome disease effectively can be improved, help too serious hysteromyoma atrophy and chocolate cyst of ovary need make great efforts to improve.
Embodiment 9
Experimenter: so-and-so Miss desolate, 1972 births, 41 years old, height 158cm, body weight 55kg.
Residence: new northern city tree forest zone.Occupation: breakfast dealer.Disease: have uterine prolapse, hysteromyoma disease.
Physiology phase clinical symptoms: be second phase hysteromyoma type dysmenorrhoea; Have distending pain of the breast, headache, lumbago, dizzy, emit cold sweat, angina abdominis, Hypomenorrhea, clot, menstrual period mixed and disorderly, day of rising during have the symptoms such as water clock.
Treatment improvement mode:
(1) through giving the present invention's treatment, improve women physiological period and menstrual period syndrome the draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition, early, middle and late each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4g: chocolate content 24g wraps), brew when the physiology phase rises pain on the same day and take, rear about pain relieving after more than 40 minute is taken in first time, after sustainable about 7 hours, pain symptom recurs again, need take help pain relieving again;
(2) suggestion change early, middle and late each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4.5g: chocolate content 25g wraps), take three days continuously, rear about pain relieving after more than 30 minute was taken in second day first time, take three days dysmenorrhoea symptoms nothing completely, the symptoms such as water clock are obviously improved.
Secondary month: discriminant amendment uses the present invention to treat, improve women physiological period and menstrual period syndrome the draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition, early, middle and late each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4.5g: chocolate content 25g wraps), take 7 days continuously, the physiology phase rises to take on time and wants the same day, menstrual period are normal, symptom is improved entirely without water clock symptom, and uterine prolapse, hysteromyoma there is no and obviously change phenomenon.
After continuous three months: cast draft Chinese medicine compound hysteromyoma compositions same medicine, hysteromyoma has obvious contraction without large, and uterine prolapse is then without obviously changing phenomenon.
By above-mentioned experimental result: prove through giving the present invention's treatment, improve women physiological period and menstrual period syndrome the draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition, effectively can improve second phase hysteromyoma type dysmenorrhoea symptom, effectively can improve menstrual pain syndrome disease, as long as the proof physiology phase rises, uterus is arranged menses, is peeled off normally, is effectively to help hysteromyoma to shrink.
Embodiment 10
Experimenter: so-and-so Miss of week, 1962 births, 47 years old, height 152cm, body weight 46kg.
Residence: Ilan Hsien person mountain area.Occupation: general merchandise special counter Miss service trade.Disease: hysteromyoma fibrocyst, ovary hydatoncus and first phase breast carcinoma are about 0.8cm disease.
Physiology phase clinical symptoms: between second phase hysteromyoma type and fourth phase tumorous type dysmenorrhoea; Have distending pain of the breast, headache, lumbago, dizzy, trick is felt cold, emit cold sweat, the symptom such as angina abdominis, Hypomenorrhea, clot, menstrual period are mixed and disorderly.
Therapeutic modality: through giving the present invention's treatment, improve women physiological period and menstrual period syndrome the draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition, early, middle and late each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4g: chocolate content 24g wraps), brew when the physiology phase rises pain on the same day and take, rear about pain relieving after more than 40 minute is taken in first time, after sustainable about 5 hours, symptom recurs again, need take second dose again and help pain relieving symptom; Reconstruction view early, middle and late each 4.5 takes three days continuously, takes rear about pain relieving after more than 40 minute in second day first time, and taking three days dysmenorrhoea symptoms has and improve gradually.
Secondary month: through giving the present invention's treatment, improve women physiological period and menstrual period syndrome the draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition, early, middle and late each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4.5g: chocolate content 25g wraps), take 7 continuously, it is normal that result improves menstrual period, and dysmenorrhoea symptom is obviously improved.
After continuous some months: advise through giving the present invention's treatment, improve women physiological period and menstrual period syndrome the draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition, early, middle and late each once (the chocolate draft Traditional Chinese medicine compound composition one of Chinese medicine content 4.5g: chocolate content 25g wraps), take 7 ~ 15 days continuously, since taking on time, result hysteromyoma fibrocyst is no longer grown up, obvious contraction, but its breast carcinoma, ovary hydatoncus, there is no and effectively improve phenomenon.
By above-mentioned experimental result: prove the present invention treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, effectively can to improve between second phase hysteromyoma type and the fourth phase tumorous type pain symptom in menstrual period, can effectively suppress to improve hysteromyoma fibrocyst dysmenorrhoea syndrome, but improve breast carcinoma, ovary hydatoncus disease without obviously suppressing, as long as the proof physiology phase rises, uterus is arranged menses, is peeled off normally, helps uterus to suppress to improve muscular tumor hypertrophy only.
Embodiment table 1
Embodiment table 2
Above institute embodiment be only the present invention treatment, improve women physiological period and menstrual period syndrome chocolate draft Traditional Chinese medicine compound composition, some enforcements of compositions pharmacological effect, be not used to the scope limiting the invention process, generally simple equivalence change and the amendment for it according to draft Traditional Chinese medicine compound composition claim of the present invention and embodiment thought that description of the present invention disclosed or relative components, must belong to patent of the present invention and contain it.

Claims (9)

1. treat, improve women physiological period and the chocolate draft Traditional Chinese medicine compound composition of syndrome in menstrual period, it is characterized in that comprising having: cocoa chocolate powder compositions, draft Traditional Chinese medicine compound composition etc., mixing forms chocolate draft Traditional Chinese medicine compound composition;
Wherein cocoa chocolate powder compositions, the pharmacology that system uses cocoa powder body to have, ascending, descending, floating, heavy, abnormal smells from the patient, Gui Jing, characteristic, with in the intrinsic rationale of Chinese medicine, collocation combine there is treatment, improve women physiological period and menstrual period syndrome slight illness various draft Traditional Chinese medicine compound composition formula, the effect reach treatment, improving, reaches the chocolate draft Traditional Chinese medicine compound composition improving with meet domestic and abroad personage and young maiden or all acceptable mouthfeel of adult female and the sense of taste and enjoy;
Wherein cocoa chocolate powder compositions, for the preferred embodiment compositions of general known techniques, wherein include: cocoa powder 5 ~ 15g, sugar 4 ~ 12g, skim milk 3 ~ 8g, vegetable oil 1 ~ 5g, Sal 0.1 ~ 1g, antler glue 0.1 ~ 1g, natural perfume material 0.1 ~ 1g etc., mixing composition cocoa chocolate powder organic compound 14 ~ 24g; Various different flavor mouthfeel combination collocation is done according to actual demand;
This draft Traditional Chinese medicine compound composition, the pharmacology that system uses Chinese medicine to have, rise, fall, floating, heavy, abnormal smells from the patient, Gui Jing, characteristic, rationale intrinsic with Chinese medicine, coordinate the monarch of pharmacology, minister, assistant, make to wait four large machines to turn basic principle collocation mixing cocoa chocolate, allly to be used for the treatment of, improve women physiological period and the menstrual period ailing draft Traditional Chinese medicine compound composition with hysteromyoma, the enforcement aspect of its pharmacological treatment and the various draft Traditional Chinese medicine compound composition formula of embodiment thought and relative components etc., all have treatment, improve, prevention women physiological period and menstrual period syndrome, the various pain that health produces, the various draft Traditional Chinese medicine compound composition formula of uncomfortable disease and hysteromyoma etc.
2. treat described in, improve women physiological period and menstrual period syndrome draft Chinese medicine compound dysmenorrhoea in the menstrual period syndrome compositions of one of chocolate draft Traditional Chinese medicine compound composition combination formula, its formula content includes: Herba Pogostemonis 0.3 ~ 6g, Folium Perillae 0.3 ~ 6g, Pericarpium Citri Reticulatae (Pericarpium Citri tangerinae) 0.3 ~ 10g, the Radix Angelicae Dahuricae 0.3 ~ 10g, yeast (Massa Medicata Fermentata, Monas cuspurpureus Went) 0.3 ~ 15g, Rhizoma Zingiberis Recens 0.3 ~ 5g, Oletum Trogopterori 0.3 ~ 8g, Cang Intraoperative 0.5 ~ 4.5g, Cortex Magnoliae Officinalis 0.5 ~ 4.5g, Radix Angelicae Sinensis 0.3 ~ 12g, Folium Artemisiae Argyi 0.3 ~ 10g, Rhizoma Chuanxiong 0.3 ~ 10g, Radix Achyranthis Bidentatae 0.3 ~ 8g, beautiful Ramulus Cinnamomi 0.3 ~ 10g, Rhizoma Corydalis 0.3 ~ 10g, Cortex Moutan 0.3 ~ 9g, Radix Paeoniae 0.3 ~ 10g, Semen Persicae 0.3 ~ 12g, Flos Carthami 0.3 ~ 6g, Radix Platycodonis 0.3 ~ 4.5g, Fructus Foeniculi 0.3 ~ 3g, Poria 0.3 ~ 6g etc., after the concentrated preparation of science, dosage is made to be 3.5 ~ 18g, for the present invention is exclusively used in treatment, improves draft Chinese medicine compound syndrome in the menstrual period compositions of women physiological period and syndrome in menstrual period first phase GENERAL TYPE dysmenorrhoea and second phase hysteromyoma type dysmenorrhoea.
3. treat described in, improve women physiological period and menstrual period syndrome another draft Chinese medicine compound hysteromyoma dysmenorrhoea compositions of chocolate draft Traditional Chinese medicine compound composition combination formula, its formula content includes: Radix Angelicae Sinensis 0.3 ~ 12g, Rhizoma Chuanxiong 0.3 ~ 10g, beautiful osmanthus 0.3 ~ 10g, Rhizoma Corydalis 0.3 ~ 10g, Radix Paeoniae 0.3 ~ 10g, Radix Platycodonis 0.3 ~ 4.5g, Folium Perillae 0.3 ~ 6g, the Radix Angelicae Dahuricae 0.3 ~ 10g, yeast (Massa Medicata Fermentata, Monas cuspurpureus Went) 0.3 ~ 15g, Rhizoma Zingiberis Recens 0.3 ~ 5g, Oletum Trogopterori 0.3 ~ 8g, Semen Arecae 0.3 ~ 6g, Cang Intraoperative 0.3 ~ 4.5g, Cortex Magnoliae Officinalis 0.3 ~ 4.5g, Flos Carthami 0.3 ~ 6g, Fructus Gardeniae 0.3 ~ 10g, Rhizoma Cyperi 0.3 ~ 10g, Radix Glycyrrhizae 0.3 ~ 12g, Radix Ginseng 0.3 ~ 15g, the Radix Linderae 0.3 ~ 10g, the Radix Aucklandiae 0.3 ~ 9g, Radix Saposhnikoviae 0.3 ~ 10g, Fructus Aurantii 0.3 ~ 9g, Radix Astragali 0.3 ~ 15g etc., after the concentrated preparation of science, dosage is made to be 3.5 ~ 18g, for the present invention is exclusively used in treatment treatment, improves the draft Chinese medicine compound hysteromyoma compositions that women physiological period and syndrome in menstrual period second phase hysteromyoma type dysmenorrhoea treat female myoma of uterus disease.
4. treat according to claim 1, improve women physiological period and menstrual period syndrome the draft Traditional Chinese medicine compound composition of chocolate draft Traditional Chinese medicine compound composition, can be crude drug decoction pieces and decoct, or extraction is extracted; Extraction is extracted system and is prepared with water extraction or wine extraction mode.
5. treat according to claim 1, improve women physiological period and menstrual period syndrome the draft Traditional Chinese medicine compound composition of chocolate draft Traditional Chinese medicine compound composition, the mode of condensing mode system science concentrated traditional Chinese medicine (scientificallyconcentratedtraditionalChinesemedicine).
6. treat according to claim 1, improve women physiological period and menstrual period syndrome the cocoa chocolate powder compositions of chocolate draft Traditional Chinese medicine compound composition and draft Traditional Chinese medicine compound composition, the collocation such as all said compositions mixing cocoa chocolate is the compositions being exclusively used in treatment, improving women physiological period and all diseases of syndrome in menstrual period etc.; This all disease has, all diseases of first phase GENERAL TYPE dysmenorrhoea and all diseases of second phase hysteromyoma type dysmenorrhoea; As, dysmenorrhoea is had a headache, have a dizzy spell, vomit, aching pain in waist and back, lower limb are aching and limp, distention and pain in the lower abdomen, distending pain of the breast, emit cold sweat, trick is felt cold, appetite disorder; The different imbalance of hormone, whole face small pox, dry mouth and tougue, bitter taste in the mouth and dry throat, susceptible to lose temper due to restlessness, breast mammary swelling pain, neurolysis, spirit depressing, asthenia drowsiness, the symptoms such as cardiopalmus is felt sick, dysthymic disorder, depressed, short-tempered, sleep disorder, leucorrhea; The symptoms such as the advanced menstruation that diseases caused by exogenous pathogenic factor cause, delays mixed and disorderly, and the few matter of amount is light, and row's blood is not smooth, and amenorrhea blood is fast, hysteromyoma, and endometriosis, pelvic inflammatory disease, basin peritonitis, oviduct are scorching.
7. treat according to claim 2,3, improve women physiological period and the draft Traditional Chinese medicine compound composition formula of chocolate draft Traditional Chinese medicine compound composition of syndrome in menstrual period, can be crude drug decoction pieces and decoct, or extraction, extraction; Extraction, extraction system are prepared with water extraction or wine extraction mode.
8. described treatment according to claim 2,3, improve women physiological period and menstrual period syndrome the draft Traditional Chinese medicine compound composition of chocolate draft Traditional Chinese medicine compound composition, the mode of condensing mode system science concentrated traditional Chinese medicine (scientificallyconcentratedtraditionalChinesemedicine).
9. treat according to claim 2,3, improve women physiological period and menstrual period syndrome the draft Traditional Chinese medicine compound composition formula of chocolate draft Traditional Chinese medicine compound composition, said composition system is exclusively used in treatment, improves women physiological period and all diseases of syndrome in menstrual period, this all disease has, all diseases of first phase GENERAL TYPE dysmenorrhoea and all diseases of second phase hysteromyoma type dysmenorrhoea; As, dysmenorrhoea is had a headache, have a dizzy spell, vomit, aching pain in waist and back, lower limb are aching and limp, distention and pain in the lower abdomen, distending pain of the breast, emit cold sweat, trick is felt cold, appetite disorder; The different imbalance of hormone, whole face small pox, dry mouth and tougue, bitter taste in the mouth and dry throat, susceptible to lose temper due to restlessness, breast mammary swelling pain, neurolysis, spirit depressing, asthenia drowsiness, the symptoms such as cardiopalmus is felt sick, dysthymic disorder, depressed, short-tempered, sleep disorder, leucorrhea abnormal; The symptoms such as the advanced menstruation that diseases caused by exogenous pathogenic factor cause, delays mixed and disorderly, and the few matter of amount is light, and row's blood is not smooth, and amenorrhea blood is fast, hysteromyoma, and endometriosis, pelvic inflammatory disease, basin peritonitis, oviduct are scorching.
CN201410327480.2A 2014-07-10 2014-07-10 Compound chocolate Chinese herbal composition for treating and improving menstrual syndrome of females Pending CN105267906A (en)

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CN111165765A (en) * 2020-01-14 2020-05-19 杭州不戒健康科技有限公司 Composition and jelly with effect of relieving dysmenorrhea and preparation method of composition and jelly
CN111398505A (en) * 2020-04-28 2020-07-10 健民药业集团股份有限公司 Method for simultaneously detecting contents of five components of traditional Chinese medicine for treating infantile enuresis
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