CN102209534A - 包封含脂肪酸油乳剂的多糖胶囊 - Google Patents

包封含脂肪酸油乳剂的多糖胶囊 Download PDF

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Publication number
CN102209534A
CN102209534A CN2009801446021A CN200980144602A CN102209534A CN 102209534 A CN102209534 A CN 102209534A CN 2009801446021 A CN2009801446021 A CN 2009801446021A CN 200980144602 A CN200980144602 A CN 200980144602A CN 102209534 A CN102209534 A CN 102209534A
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capsule
fatty acid
oil
weight
oil mixture
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CN2009801446021A
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Chinese (zh)
Inventor
冈纳.伯治
斯维恩.O.赫斯特维特
托马斯.安德森
奥拉夫.加泽罗德
佩德.O.安德森
克里斯琴.K.拉森
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Pronova Biocare AS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)
CN2009801446021A 2008-09-10 2009-09-10 包封含脂肪酸油乳剂的多糖胶囊 Pending CN102209534A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/207,824 2008-09-10
US12/207,824 US20100062057A1 (en) 2008-09-10 2008-09-10 Formulation
PCT/IB2009/006933 WO2010029433A1 (en) 2008-09-10 2009-09-10 A polysaccharide capsule enclosing a fatty acid oil-containing emulsion

Publications (1)

Publication Number Publication Date
CN102209534A true CN102209534A (zh) 2011-10-05

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CN2009801446021A Pending CN102209534A (zh) 2008-09-10 2009-09-10 包封含脂肪酸油乳剂的多糖胶囊

Country Status (11)

Country Link
US (2) US20100062057A1 (https=)
EP (1) EP2341901A4 (https=)
JP (1) JP2012502090A (https=)
KR (1) KR20110058881A (https=)
CN (1) CN102209534A (https=)
AU (1) AU2009290542A1 (https=)
BR (1) BRPI0918429A2 (https=)
CA (1) CA2736812A1 (https=)
EA (1) EA201170433A1 (https=)
MX (1) MX2011002640A (https=)
WO (1) WO2010029433A1 (https=)

Cited By (8)

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CN102596251A (zh) * 2009-09-10 2012-07-18 Fmc有限公司 高强度无缝海藻酸盐胶囊
CN104812379A (zh) * 2012-09-13 2015-07-29 克利塞利斯医药有限公司 一种药物组合物
CN107106501A (zh) * 2014-12-23 2017-08-29 Fmc有限公司 肠溶膜包衣组合物、包覆方法以及包覆的制剂
CN107846960A (zh) * 2015-06-03 2018-03-27 安纳生物科技有限公司 含稳定脂质的微胶囊及其制备方法
CN108704588A (zh) * 2018-06-29 2018-10-26 广西壮族自治区林业科学研究院 一种微胶囊化酸性水溶液的制备方法
CN110101692A (zh) * 2012-06-29 2019-08-09 阿玛林制药爱尔兰有限公司 治疗儿童代谢综合征的方法
CN113727705A (zh) * 2019-04-30 2021-11-30 帝斯曼知识产权资产管理有限公司 新型多不饱和脂肪酸递送系统
CN118575949A (zh) * 2024-04-22 2024-09-03 嘉必优生物技术（武汉）股份有限公司 一种多不饱和脂肪酸油脂微胶囊及其制备方法和应用

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102596251A (zh) * 2009-09-10 2012-07-18 Fmc有限公司 高强度无缝海藻酸盐胶囊
CN102596251B (zh) * 2009-09-10 2014-06-11 Fmc有限公司 高强度无缝海藻酸盐胶囊
CN110101692A (zh) * 2012-06-29 2019-08-09 阿玛林制药爱尔兰有限公司 治疗儿童代谢综合征的方法
CN104812379A (zh) * 2012-09-13 2015-07-29 克利塞利斯医药有限公司 一种药物组合物
CN107106501A (zh) * 2014-12-23 2017-08-29 Fmc有限公司 肠溶膜包衣组合物、包覆方法以及包覆的制剂
CN107106501B (zh) * 2014-12-23 2021-07-06 杜邦营养美国有限公司 肠溶膜包衣组合物、包覆方法以及包覆的制剂
CN107846960A (zh) * 2015-06-03 2018-03-27 安纳生物科技有限公司 含稳定脂质的微胶囊及其制备方法
CN108704588A (zh) * 2018-06-29 2018-10-26 广西壮族自治区林业科学研究院 一种微胶囊化酸性水溶液的制备方法
CN108704588B (zh) * 2018-06-29 2020-10-09 广西壮族自治区林业科学研究院 一种微胶囊化酸性水溶液的制备方法
CN113727705A (zh) * 2019-04-30 2021-11-30 帝斯曼知识产权资产管理有限公司 新型多不饱和脂肪酸递送系统
CN118575949A (zh) * 2024-04-22 2024-09-03 嘉必优生物技术（武汉）股份有限公司 一种多不饱和脂肪酸油脂微胶囊及其制备方法和应用

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AU2009290542A1 (en) 2010-03-18
CA2736812A1 (en) 2010-03-18
US20100062057A1 (en) 2010-03-11
KR20110058881A (ko) 2011-06-01
US20110262534A1 (en) 2011-10-27
EP2341901A4 (en) 2013-07-17
AU2009290542A2 (en) 2011-03-31
EA201170433A1 (ru) 2011-10-31
JP2012502090A (ja) 2012-01-26

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