CN102205144A - 医用金属植入材料多孔钽及其制备方法 - Google Patents
医用金属植入材料多孔钽及其制备方法 Download PDFInfo
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- B22F3/00—Manufacture of workpieces or articles from metallic powder characterised by the manner of compacting or sintering; Apparatus specially adapted therefor ; Presses and furnaces
- B22F3/10—Sintering only
- B22F3/11—Making porous workpieces or articles
- B22F3/1121—Making porous workpieces or articles by using decomposable, meltable or sublimatable fillers
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Abstract
Description
实施例 | 钽粉粒径(微米)/氧含量小于(%) | 聚乙烯醇(克)/水(毫升) | 钽粉(重量份)/聚乙烯醇水溶液(重量份) | 聚氨酯泡沫孔径(mm) | 聚氨酯泡沫密度(g/cm3) | 聚氨酯泡沫硬度(°) |
7 | 小于43/0.1% | 2/100 | 1/7.5 | 0.50 | 0.025 | 50 |
8 | 小于40/0.1% | 3/100 | 1/8.5 | 0.88 | 0.035 | 55 |
9 | 小于42/0.1% | 4/100 | 1/7.7 | 0.70 | 0.030 | 77 |
10 | 小于41/0.1% | 5/100 | 1/8.3 | 0.60 | 0.027 | 66 |
11 | 小于39/0.1% | 6/100 | 1/6.0 | 0.55 | 0.033 | 73 |
12 | 小于38/0.1% | 7/100 | 1/7.3 | 0.56 | 0.016 | 63 |
13 | 小于35/0.1% | 8/100 | 1/8.1 | 0.72 | 0.018 | 53 |
实施例 | 干燥真空度(Pa)/温度(℃)/时间(小时) | 脱脂气氛(Pa)/温度(℃)/时间(min) | 烧结气氛(Pa)/温度(℃)/时间(min) | 退火气氛(Pa)/升温或降温速率(℃/min)温度(℃)/保温时间(min) |
7 | 1/65/6.5 | 以1℃/min的速率从室温升至400℃,保温60min/0.5℃/min的速率从400℃升至600℃,保温120min | 10℃/min的速率从室温升至1200℃,保温60min,真空度为10-4Pa;以11℃/min的速率升至1250℃,保温60min;以6℃/min的速率升至2030℃,保温240min,真空度为10-3Pa;真空度为10-4Pa~10-3Pa;以11℃/min的速率冷却至1520℃,保温60min;以13℃/min的速率冷却至1200℃,保温90min;以13℃/min的速率冷却至800℃,然后随炉冷却 | 10-4Pa/15℃/min的速率升至1030℃,保温480min/5℃/min的速率冷却至1000℃,保温180min/以11℃/min的速率冷却至800℃,保温108min/21℃/min的速率冷却至室温 |
8 | 1/75/5.5 | 1.5℃/min的速率从室温升至400℃,保温58min/0.6℃/min的速率从400℃升至650℃,保温110min | 11℃/min的速率从室温升至1210℃,保温58min,真空度为10-4Pa;以12℃/min的速率升至1270℃,保温55min;以8℃/min的速率升至2050℃,保温220min,真空度为10-3Pa;真空度为10-4Pa~10-3Pa;以12℃/min的速率冷却至1530℃,保温55min;以14℃/min的速率冷却至1210℃,保温85min;以14℃/min的速率冷却至800℃,然后随炉冷却 | 10-3Pa/17℃/min的速率升至1050℃,保温450min/6℃/min的速率冷却至1000℃,保温150min/以12℃/min的速率冷却至800℃,保温102min/22℃/min的速率冷却至室温 |
9 | 1/55/7 | 以2℃/min的速率从室温升至400℃,保温56min/0.7℃/min的速率从400℃升至680℃,保温100min | 12℃/min的速率从室温升至1220℃,保温55min,真空度为10-4Pa;以13℃/min的速率升至1300℃,保温50min;以10℃/min的速率升至2100℃,保温200min,真空度为10-3Pa;真空度为10-4Pa~10-3Pa;以13℃/min的速率冷却至1540℃,保温50min;以15℃/min的速率冷却至1220℃,保温80min;以15℃/min的速率冷却至800℃,然后随炉冷却 | 10-3Pa/20℃/min的速率升至1100℃,保温420min/7℃/min的速率冷却至1000℃,保温130min/以13℃/min的速率冷却至800℃,保温96min/23℃/min的速率冷却至室温 |
10 | 1/45/7.5 | 2.5℃/min的速率从室温升至400℃,保温55min/0.8℃/min的速率从400℃升至700℃,保温90min | 13℃/mim的速率从室温升至1230℃,保温50min,真空度为10-4Pa;以14℃/min的速率升至1350℃,保温45min;以12℃/min的速率升至2150℃,保温180min,真空度为10-3Pa;真空度为10-4Pa~10-3Pa;以14℃/min的速率冷却至1550℃,保温45min;以16℃/min的速率冷却至1230℃,保温75min;以16℃/min的速率冷却至800℃,然后随炉冷却 | 10-4Pa/22℃/min的速率升至1150℃,保温360min/8℃/min的速率冷却至1000℃,保温120min/以14℃/min的速率冷却至800℃,保温90min/24℃/min的速率冷却至室温 |
11 | 1/85/6.0 | 3℃/min的速率从室温升至400℃,保温50min/0.9℃/min的速率从400℃升至730℃,保温80min | 14℃/min的速率从室温升至1240℃,保温40min,真空度为10-4Pa;以15℃/min的速率升至1400℃,保温40min;以14℃/min的速率升至2160℃,保温160min,真空度为10-3Pa;真空度为10-4Pa~10-3Pa;以15℃/min的速率冷却至1560℃,保温40min;以17℃/min的速率冷却至1240℃,保温70min;以17℃/min的速率冷却至800℃,然后随炉冷却 | 10-3Pa/25℃/min的速率升至1200℃,保温300min/9℃/min的速率冷却至1000℃,保温100min/以15℃/min的速率冷却至800℃,保温84min/26℃/min的速率冷却至室温 |
12 | 1/95/5.5 | 4℃/min的速率从室温升至400℃,保温40min/1.0℃/min的速率从400℃升至750℃,保温70min | 15℃/min的速率从室温升至1250℃,保温30min,真空度为10-4a;以16℃/min的速率升至1450℃,保温35min;以16℃/min的速率升至2170℃,保温140min,真空度为10-3a;真空度为10-4Pa~10-3Pa;以16℃/min的速率冷却至1570℃,保温35min;以18℃/min的速率冷却至1245℃,保温65min;以18℃/min的速率冷却至800℃,然后随炉冷却 | 10-4Pa/27℃/min的速率升至1230℃,保温270min/10℃/min的速率冷却至1000℃,保温90min/以16℃/min的速率冷却至800℃,保温78min/27℃/min的速率冷却至室温 |
13 | 1/100/4.5 | 5℃/min的速率从室温升至400℃,保温30min/1.3℃/min的速率从400℃升至800℃,保温60min | 13℃/min的速率从室温升至1225℃,保温45min,真空度为10-4Pa;以17℃/min的速率升至1500℃,保温30min;以18℃/min的速率升至2180℃,保温120min,真空度为10-3Pa;真空度为10-4Pa~10-3Pa;以18℃/min的速率冷却至1580℃,保温30min;以19℃/min的速率冷却至1250℃,保温60min;以19℃/min的速率冷却至800℃,然后随炉冷却 | 10-4Pa/30℃/min的速率升至1250℃,保温240min/5.5℃/min的速率冷却至1000℃,保温170min/以17℃/min的速率冷却至800℃,保温72min/29℃/min的速率冷却至室温 |
实施例 | 7 | 8 | 9 | 10 | 11 | 12 | 13 |
密度(g/cm3) | 9.9 | 7.5 | 5.8 | 4.2 | 9.1 | 3.5 | 8.3 |
孔隙率(%) | 40 | 55 | 65 | 75 | 45 | 80 | 50 |
孔径(μm) | 170 | 290 | 480 | 380 | 330 | 210 | 430 |
弹性模量(GPa) | 2.1 | 2.5 | 3.3 | 3.9 | 3.6 | 4.3 | 4.5 |
屈服强度(MPa) | 110 | 100 | 90 | 80 | 70 | 65 | 40 |
抗压强度(MPa) | 50 | 160 | 150 | 130 | 100 | 140 | 110 |
硬度(MPa) | 160 | 170 | 210 | 230 | 280 | 290 | 270 |
塑性变形量(%) | 17.30 | 17.20 | 17.25 | 17.22 | 17.28 | 17.29 | 17.30 |
抗拉强度(MPa) | 65 | 66 | 67 | 68 | 69 | 70 | 71 |
断后延展率(%) | 14.70 | 14.60 | 14.50 | 14.65 | 14.55 | 14.75 | 14.80 |
烧结颈断裂率(%) | 45 | 40 | 35 | 30 | 43 | 37 | 32 |
颗粒内部断裂率(%) | 55 | 60 | 65 | 70 | 57 | 63 | 68 |
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CN201010136854.4A CN102205144B (zh) | 2010-03-31 | 2010-03-31 | 医用金属植入材料多孔钽及其制备方法 |
PCT/CN2010/076706 WO2011120280A1 (zh) | 2010-03-31 | 2010-09-08 | 医用金属植入材料多孔钽及其制备方法 |
ES10848739.8T ES2652594T3 (es) | 2010-03-31 | 2010-09-08 | Tantalio poroso metálico usado como material para implante médico y método de preparación del mismo |
EP10848739.8A EP2554187B1 (en) | 2010-03-31 | 2010-09-08 | Metal porous tantalum used as medical implant material and preparation method thereof |
US13/581,799 US20130011691A1 (en) | 2010-03-31 | 2010-09-08 | Porous tantalum used for medical implantation and method for preparing the same |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1479635A (zh) * | 2000-12-06 | 2004-03-03 | ��˹���տƼ���˾ | 具有改善的生物相容性的医用假体器件和移植物 |
CN1658914A (zh) * | 2002-04-09 | 2005-08-24 | 艾斯特勒科技公司 | 具有改良生物相容性的医用假体装置 |
WO2006029621A1 (de) * | 2004-09-15 | 2006-03-23 | Glatt Gmbh | Knochenersatzimplantat für human- und veterinärmedizinische anwendungen |
WO2008078164A2 (en) * | 2006-12-21 | 2008-07-03 | Numat As | Metal oxide scaffolds |
EP2149414A1 (en) * | 2008-07-30 | 2010-02-03 | Nederlandse Centrale Organisatie Voor Toegepast Natuurwetenschappelijk Onderzoek TNO | Method of manufacturing a porous magnesium, or magnesium alloy, biomedical implant or medical appliance. |
CN101660076A (zh) * | 2009-10-14 | 2010-03-03 | 北京师范大学 | 有机泡沫浸浆烧结法制备宏观网状多孔钽 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5282861A (en) | 1992-03-11 | 1994-02-01 | Ultramet | Open cell tantalum structures for cancellous bone implants and cell and tissue receptors |
WO2002066693A1 (en) * | 2001-02-19 | 2002-08-29 | Isotis N.V. | Porous metals and metal coatings for implants |
US7458991B2 (en) * | 2002-02-08 | 2008-12-02 | Howmedica Osteonics Corp. | Porous metallic scaffold for tissue ingrowth |
DE102004032128B4 (de) * | 2003-10-17 | 2010-10-14 | W.C. Heraeus Gmbh | Metallischer Werkstoff, Herstellverfahren und Verwendung |
US8383187B2 (en) * | 2009-02-19 | 2013-02-26 | Depuy Products, Inc. | Rough porous constructs |
-
2010
- 2010-03-31 CN CN201010136854.4A patent/CN102205144B/zh active Active
- 2010-09-08 US US13/581,799 patent/US20130011691A1/en not_active Abandoned
- 2010-09-08 ES ES10848739.8T patent/ES2652594T3/es active Active
- 2010-09-08 WO PCT/CN2010/076706 patent/WO2011120280A1/zh active Application Filing
- 2010-09-08 EP EP10848739.8A patent/EP2554187B1/en active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1479635A (zh) * | 2000-12-06 | 2004-03-03 | ��˹���տƼ���˾ | 具有改善的生物相容性的医用假体器件和移植物 |
CN1658914A (zh) * | 2002-04-09 | 2005-08-24 | 艾斯特勒科技公司 | 具有改良生物相容性的医用假体装置 |
WO2006029621A1 (de) * | 2004-09-15 | 2006-03-23 | Glatt Gmbh | Knochenersatzimplantat für human- und veterinärmedizinische anwendungen |
WO2008078164A2 (en) * | 2006-12-21 | 2008-07-03 | Numat As | Metal oxide scaffolds |
EP2149414A1 (en) * | 2008-07-30 | 2010-02-03 | Nederlandse Centrale Organisatie Voor Toegepast Natuurwetenschappelijk Onderzoek TNO | Method of manufacturing a porous magnesium, or magnesium alloy, biomedical implant or medical appliance. |
CN101660076A (zh) * | 2009-10-14 | 2010-03-03 | 北京师范大学 | 有机泡沫浸浆烧结法制备宏观网状多孔钽 |
Non-Patent Citations (3)
Title |
---|
《河北工业大学学报》 20031231 刘朝红等 有机泡沫浸渍法制备多孔beta-TCP支架及生物相容性研究 河北工业大学 全文 1-12 第32卷, 第6期 * |
刘朝红等: "有机泡沫浸渍法制备多孔β-TCP支架及生物相容性研究", 《河北工业大学学报》, vol. 32, no. 6, 31 December 2003 (2003-12-31) * |
周作平等: "《粉末冶金机械零件实用技术》", 31 January 2006, article "烧结的基本原理", pages: 290 * |
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Also Published As
Publication number | Publication date |
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EP2554187A1 (en) | 2013-02-06 |
ES2652594T3 (es) | 2018-02-05 |
WO2011120280A1 (zh) | 2011-10-06 |
US20130011691A1 (en) | 2013-01-10 |
CN102205144B (zh) | 2014-07-16 |
EP2554187B1 (en) | 2017-11-08 |
EP2554187A4 (en) | 2014-07-09 |
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