CN102202668A - 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品 - Google Patents

磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品 Download PDF

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CN102202668A
CN102202668A CN2009801431736A CN200980143173A CN102202668A CN 102202668 A CN102202668 A CN 102202668A CN 2009801431736 A CN2009801431736 A CN 2009801431736A CN 200980143173 A CN200980143173 A CN 200980143173A CN 102202668 A CN102202668 A CN 102202668A
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mtor
hydrogen
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C·加西亚-埃切夫埃里亚
S-M·马伊拉
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Novartis AG
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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CN2009801431736A 2008-10-31 2009-10-29 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品 Pending CN102202668A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510402018.9A CN105030784A (zh) 2008-10-31 2009-10-29 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08168044.9 2008-10-31
EP08168044 2008-10-31
PCT/EP2009/064274 WO2010049481A1 (en) 2008-10-31 2009-10-29 Combination of a phosphatidylinositol-3-kinase (pi3k) inhibitor and a mtor inhibitor

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201510402018.9A Division CN105030784A (zh) 2008-10-31 2009-10-29 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品

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CN102202668A true CN102202668A (zh) 2011-09-28

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CN201510402018.9A Pending CN105030784A (zh) 2008-10-31 2009-10-29 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品
CN2009801431736A Pending CN102202668A (zh) 2008-10-31 2009-10-29 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品

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CN201510402018.9A Pending CN105030784A (zh) 2008-10-31 2009-10-29 磷脂酰肌醇-3-激酶(PI3K)抑制剂和mTOR抑制剂的组合产品

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US (3) US20110195966A1 (enExample)
EP (1) EP2349275B1 (enExample)
JP (4) JP2012506898A (enExample)
KR (1) KR20110090911A (enExample)
CN (2) CN105030784A (enExample)
AU (1) AU2009309616B2 (enExample)
BR (1) BRPI0921802A8 (enExample)
CA (1) CA2736361C (enExample)
ES (1) ES2627677T3 (enExample)
MX (1) MX2011004585A (enExample)
RU (2) RU2538683C2 (enExample)
WO (1) WO2010049481A1 (enExample)

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TWI592411B (zh) 2011-02-23 2017-07-21 英特爾立秦有限責任公司 激酶抑制劑之組合及其用途
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DK2968281T3 (da) 2013-03-13 2020-11-02 Univ Texas Mtor-hæmmere til forebyggelse af vækst af tarmpolyp
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KR20150131224A (ko) 2013-03-14 2015-11-24 노파르티스 아게 돌연변이 idh의 억제제로서의 3-피리미딘-4-일-옥사졸리딘-2-온
KR20150130451A (ko) 2013-03-15 2015-11-23 제넨테크, 인크. 암 치료 방법 및 항암제 내성 예방을 위한 방법
EA038235B1 (ru) * 2013-05-01 2021-07-28 Ф.Хоффманн-Ля Рош Аг Бигетероарильные соединения и их применения
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CA2933908C (en) 2013-12-31 2024-01-30 Rapamycin Holdings, Llc Oral rapamycin nanoparticle preparations and use
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CA3019311A1 (en) 2015-04-15 2016-10-20 University Of Massachusetts Compositions and methods for xi chromosome reactivation
EP3297629A1 (en) 2015-05-20 2018-03-28 Novartis AG Pharmaceutical combination of everolimus with dactolisib
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CN112294967A (zh) * 2020-09-30 2021-02-02 四川大学 一种mTOR抑制剂与抗癌药物的用途

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103483345A (zh) * 2013-09-25 2014-01-01 中山大学 Pi3k 激酶抑制剂、包含其的药物组合物及其应用
CN103483345B (zh) * 2013-09-25 2016-07-06 中山大学 Pi3k激酶抑制剂、包含其的药物组合物及其应用

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AU2009309616A1 (en) 2010-05-06
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