CN102177240A - 表达载体及其方法 - Google Patents

表达载体及其方法 Download PDF

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Publication number
CN102177240A
CN102177240A CN2009801361447A CN200980136144A CN102177240A CN 102177240 A CN102177240 A CN 102177240A CN 2009801361447 A CN2009801361447 A CN 2009801361447A CN 200980136144 A CN200980136144 A CN 200980136144A CN 102177240 A CN102177240 A CN 102177240A
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China
Prior art keywords
seq
sequence
expression vector
expression
nucleic acid
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Pending
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CN2009801361447A
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English (en)
Chinese (zh)
Inventor
V·M·帕特尔
S·梅特亚
A·维亚斯
G·切拉帕
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Avesthagen Ltd
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Avesthagen Ltd
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Publication of CN102177240A publication Critical patent/CN102177240A/zh
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CN2009801361447A 2008-08-12 2009-08-12 表达载体及其方法 Pending CN102177240A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN01941/CHE/2008 2008-08-12
IN1941CH2008 2008-08-12
PCT/IB2009/006517 WO2010018444A2 (fr) 2008-08-12 2009-08-12 Vecteur d'expression et son procédé

Publications (1)

Publication Number Publication Date
CN102177240A true CN102177240A (zh) 2011-09-07

Family

ID=41669395

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801361447A Pending CN102177240A (zh) 2008-08-12 2009-08-12 表达载体及其方法

Country Status (10)

Country Link
EP (1) EP2331693A2 (fr)
JP (1) JP2012506694A (fr)
KR (1) KR20110044769A (fr)
CN (1) CN102177240A (fr)
AU (1) AU2009280913A1 (fr)
BR (1) BRPI0918008A2 (fr)
CA (1) CA2736580A1 (fr)
MX (1) MX2011001644A (fr)
WO (1) WO2010018444A2 (fr)
ZA (1) ZA201101882B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103740756A (zh) * 2013-12-25 2014-04-23 中国农业大学 一种可调控删除的非病毒游离载体及其构建方法

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010049777A1 (fr) * 2008-10-28 2010-05-06 Avesthagen Limited Vecteur d’expression et procédés
WO2011015924A2 (fr) * 2009-08-03 2011-02-10 Avesthagen Limited Vecteurs et composés pour expression du trastuzumab de recombinaison
WO2011015916A2 (fr) * 2009-08-03 2011-02-10 Avesthagen Limited Vecteurs et composés pour expression d’infliximab recombinant
WO2011015918A2 (fr) * 2009-08-03 2011-02-10 Avesthagen Limited Vecteurs et composés pour l'expression de cetuximab de recombinaison
WO2011015917A2 (fr) * 2009-08-03 2011-02-10 Avesthagen Limited Vecteurs et composés pour expression de tnk-tpa recombinant (tenecteplase)
GB201213117D0 (en) * 2012-07-24 2012-09-05 Ucl Business Plc Transgene expression
WO2019057774A1 (fr) * 2017-09-19 2019-03-28 Deutsches Krebsforschungszentrum Vecteurs d'adn non intégrants pour la modification génétique de cellules
ES2821655T3 (es) * 2017-09-19 2021-04-27 Deutsches Krebsforsch Vectores de ADN no integrantes para la modificación genética de células
WO2019088257A1 (fr) * 2017-11-02 2019-05-09 国立大学法人鳥取大学 Procédé de production à haut rendement d'une protéine à l'aide d'un vecteur de chromosome artificiel de mammifère

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2123593C (fr) * 1992-09-15 2000-03-14 Craig A. Smith Methode de traitement de l'inflammation dependante du tnf a l'aide d'antagonistes du facteur de necrose tumorale
US7541512B2 (en) * 2001-03-30 2009-06-02 Synageva Biopharma Corp. Avians containing a lysozyme promoter transgene
ATE514783T1 (de) * 2003-11-12 2011-07-15 Schering Corp Plasmidsystem zur expression mehrerer gene

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103740756A (zh) * 2013-12-25 2014-04-23 中国农业大学 一种可调控删除的非病毒游离载体及其构建方法

Also Published As

Publication number Publication date
WO2010018444A3 (fr) 2010-05-14
BRPI0918008A2 (pt) 2018-07-17
AU2009280913A1 (en) 2010-02-18
ZA201101882B (en) 2012-07-25
WO2010018444A2 (fr) 2010-02-18
KR20110044769A (ko) 2011-04-29
EP2331693A2 (fr) 2011-06-15
MX2011001644A (es) 2011-10-06
CA2736580A1 (fr) 2010-02-18
JP2012506694A (ja) 2012-03-22

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Application publication date: 20110907