CN102144716A - Herba epimedii extract feedstuff additive and preparation method thereof - Google Patents

Herba epimedii extract feedstuff additive and preparation method thereof Download PDF

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Publication number
CN102144716A
CN102144716A CN2010190630522A CN201019063052A CN102144716A CN 102144716 A CN102144716 A CN 102144716A CN 2010190630522 A CN2010190630522 A CN 2010190630522A CN 201019063052 A CN201019063052 A CN 201019063052A CN 102144716 A CN102144716 A CN 102144716A
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China
Prior art keywords
filtrate
filter residue
preparation
feed addictive
shorthorned epimedium
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CN2010190630522A
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Chinese (zh)
Inventor
陈佳铭
陈炳祥
陈泽发
陈学敏
陈莎莎
陈惠真
陈伟真
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SHANGHAI BAISHU BIOTECH CO Ltd
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SHANGHAI BAISHU BIOTECH CO Ltd
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Priority to CN2010190630522A priority Critical patent/CN102144716A/en
Publication of CN102144716A publication Critical patent/CN102144716A/en
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a herba epimedii extract feedstuff additive and a preparation method thereof. The herba epimedii extract feedstuff additive is prepared by circularly extracting stems and leaves of herba epimedii many times and then uniformly mixing extracts in a carrier. The preparation method comprises the following steps of: 1, initially extracting the stems and the leaves of the herba epimedii; and 2, secondly circularly extracting residua after the extraction of the step 1, carrying out a spray drying treatment on the secondly obtained extractum and then uniformly mixing the extractum with the carrier to obtain the herba epimedii extract feedstuff additive. The herba epimedii extract feedstuff additive disclosed by the invention has the functions of tonifying the kidney and strengthening yang, dispelling wind and eliminating dampness, strengthening the muscles and bones and prompting the secretion of sperms of male animals.

Description

A kind of Shorthorned Epimedium P.E feed addictive and preparation method thereof
Technical field
The present invention relates to a kind of Shorthorned Epimedium P.E feed addictive and preparation method thereof, have tonifying kidney and strengthening yang; Dispel rheumatism; Strengthening the muscles and bones; Promote the function of buck sperm secretion, belong to natural plants additive technology field.
Background technology
At the peak season of domestic animal breeding, breeding task of sire or artificial semen collection are heavy, the easiest breeding internal lesion caused by overexertion disease that causes sire.The health that this has not only directly endangered sire has reduced the use value of sire, has also affected the breeding opportunity of dam adversely, delays production.Cause having occurred a lot of symptoms: lassitude, anorexia or do not eat.Dorsal body setae is thick disorderly contrary upright, and the back myasthenia of limbs fortune step is unstable, does not get close to dam, even be unwilling to mounting, forces mounting also to be reluctant mating, even mating, ejaculate volume is also few, and semen quality is inferior, and blood is with in sperm motility decline in the seminal fluid, and conception rate is extremely low.Serious does not then rise with crouching, slow in reacting, and the eye conjunctiva is pale, coolness of extremities, and body temperature is on the low side about 37 ℃, and what have does not then just rise at post-coitum with crouching, just slowly recovers after a while.Along with the industrialized development of China's aquaculture, though the utilization rate of sire has improved a lot, working strength has descended a lot, and still there is and is perplexing always numerous raisers' a great problem in above situation.Because the semen collection frequency is (by force) too much, differ greatly such as the ratio of sire quantity and of the right age dam, natural mating every day or manually semen collection is frequent excessively, and the duration grow (2~3 months) again, just directly caused the generation of above symptom.
Though there are numerous medicines to solve this class problem in the market, because of this type of medicine of great majority is chemical synthetic drug or hormone medicine, though temporarily solved problem, this difficult problem of the metabolic balance of breeding stock is unresolved.In the characteristics that balance metabolism, rapid-action, noresidue are arranged aspect overcoming the above problems, can be good at solving these difficult problems as the Chinese herbal medicine of one of Chinese traditional culture representative.
Though had Chinese herbal medicine to enter the feed addictive ranks at present, be of rude workmanship, most be direct pulverization process.Its active ingredient is indeterminate, consumption big, it is slow to absorb, onset is slow, and Chinese herbal medicine extract has exactly remedied above shortcoming, has few, the characteristics clear and definite, that effect is fast of checking on of consumption.Because resources of Chinese medicinal herb is in natural plants, can not produce medicament residue, can not cause bacterium, virus variation, free from environmental pollution etc. characteristics, can play the effect of alternative medicine, hormone etc.Therefore Chinese herb feed additive has very high research and utilization and is worth in advocating the journey of healthy aquaculture, green cultivation future.
Summary of the invention
The present invention is a raw material with natural barrenwort, through the processing of science, can provide comprehensive potent trophism for nerve, immunity, the internal system of animal, blood-enrich, fast quick-recovery and enhancing animal system function studies have shown that Shorthorned Epimedium P.E energy tonifying kidney and strengthening yang at present; Dispel rheumatism; Strengthening the muscles and bones; Promote the secretion of buck sperm.
Technical scheme of the present invention to achieve these goals is to adopt following means to realize:
A kind of Shorthorned Epimedium P.E feed addictive and preparation method thereof, described Shorthorned Epimedium P.E feed addictive comprises extract 2-4 part, carrier 3-6 part of the cauline leaf of barrenwort, gets through spray drying treatment and with appropriate carriers is mixed after being carried through water of twice alcohol extracting by the cauline leaf of barrenwort.
The present invention also provides a kind of preparation method of Shorthorned Epimedium P.E feed addictive, and concrete steps are as follows:
Step 1, respectively the cauline leaf of raw material barrenwort is chosen only, brachymemma, cleaning;
Step 2, raw material is packed in the alcohol extracting jar, add 75%~95% ethanol of 3~6 times of weight, boiled 3~6 hours, steam pressure is 0.4~0.7MPa, alcohol reflux;
Filter win the respectively filtrate and first filter residue after step 3, the alcohol extracting for the first time; Wherein, first filtrate is reclaimed ethanol by the decompression concentration tank, stop to reclaim until ethanol<60% that reclaims, the continuation of first filtrate concentrate concentrate;
Step 4, first filter residue add 75%~95% ethanol of 3~6 times of weight for the second time, boiled 3~6 hours, and steam pressure 0.4~0.7MPa, alcohol reflux stops to reclaim until ethanol<60% that reclaims, and filters, and gets second filtrate and second filter residue respectively;
Step 5, second filter residue boiled 1 hour once more through 6 times of water gagings, and steam pressure is that 1Mpa handles, and filters, and gets the 3rd filtrate and filter residue respectively, and filter residue discards;
Step 6, concentrate, second filtrate, the 3rd filtrate are mixed and be concentrated into proportion D=1.1~1.3, promptly get medicinal extract;
Step 7, the medicinal extract container of packing into refrigerates in 1~5 ℃ and preserves down;
Step 8, medicinal extract enter spray dryer, 175 ℃ of EATs, and 70~90 ℃ of leaving air temps promptly get Shorthorned Epimedium P.E dry powder;
Step 9, extract dry powder promptly get a kind of Shorthorned Epimedium P.E feed addictive after mixing with the carrier that is fit to.
Described carrier is preferably at least a in attapulgite, silica, pine needle meal and the maltodextrin.
Described concentrate, first filtrate, second filtrate concentrated is respectively that decompression concentrates or the interlayer concentration tank concentrates.
The present invention has following remarkable advantages and beneficial effect in sum:
1) improves sire semen quality and volume of semen;
3) reduce the breeding stock genital diseases incidence of disease, improve productivity effect;
4) natural, noresidue, have no drug resistance, have no side effect.
The specific embodiment
Below in conjunction with specific embodiment the present invention is illustrated:
A kind of Shorthorned Epimedium P.E feed addictive is made up of following parts by weight prescription: 2 parts of the extracts of barrenwort cauline leaf; 3 parts in carrier.
A kind of preparation method of Shorthorned Epimedium P.E feed addictive, concrete steps are as follows:
Step 1, respectively the cauline leaf of raw material barrenwort is chosen only, brachymemma, cleaning;
Step 2, raw material is packed in the alcohol extracting jar, add 75%~95% ethanol of 3~6 times of weight, boiled 3~6 hours, steam pressure is 0.4~0.7MPa, alcohol reflux;
Filter win the respectively filtrate and first filter residue after step 3, the alcohol extracting for the first time; Wherein, first filtrate is reclaimed ethanol by the decompression concentration tank, stop to reclaim until ethanol<60% that reclaims, the continuation of first filtrate concentrate concentrate;
Step 4, first filter residue add 75%~95% ethanol of 3~6 times of weight for the second time, boiled 3~6 hours, and steam pressure 0.4~0.7MPa, alcohol reflux stops to reclaim until ethanol<60% that reclaims, and filters, and gets second filtrate and second filter residue respectively;
Step 5, second filter residue boiled 1 hour once more through 6 times of water gagings, and steam pressure is that 1Mpa handles, and filters, and gets the 3rd filtrate and filter residue respectively, and filter residue discards;
Step 6, concentrate, second filtrate, the 3rd filtrate are mixed and be concentrated into proportion D=1.1~1.3, promptly get medicinal extract;
Step 7, the medicinal extract container of packing into refrigerates in 1~5 ℃ and preserves down;
Step 8, medicinal extract enter spray dryer, 175 ℃ of EATs, and 70~90 ℃ of leaving air temps promptly get Shorthorned Epimedium P.E dry powder;
Step 9, extract dry powder promptly get a kind of Shorthorned Epimedium P.E feed addictive after mixing with the carrier that is fit to.
Chinese herbal medicine is the natural resources of Chinese medicinal materials in China's traditional Chinese veterinary medicine.Barrenwort is the Berberidaceae plant, another name: bitter just before, HERBA EPIMEDII, celestial spirit adjoin, coptis ancestral, lung channel grass.The medicinal part of barrenwort is the cauline leaf part, and active ingredient wherein is compositions such as icariine, alkaloid.Has tonifying kidney and strengthening yang; Dispel rheumatism; Strengthening the muscles and bones; Promote the effect of buck sperm secretion.
Specify the present invention below in conjunction with embodiment:
Embodiment 1
2009.06.12----2009.07.12 during in Dong Jiang, Guangdong Province herding Co., Ltd, experimental animal adopts the Pietrain herd boar.It is as follows to have carried out contrast interpolation result of the test
Test index Test group Control group Conspicuousness
Semen volume (ml) 293 265 P<0.05
Sperm motility rate (%) 62 61 -
Sperm motility (%) 37 28 P<0.05
The respiratory tract incidence of disease 29% 34% -
The diarrhea incidence 17% 26% P<0.05
Conclusion:
1. this product can significantly improve volume of semen and sperm motility;
2. reduce the breeding stock genital diseases incidence of disease, improved Production Gain;
During use, can use by spice.During spice, complete feed per ton adds 500~1000g.
It should be noted that at last: above embodiment only in order to the explanation the present invention and and unrestricted technical scheme described in the invention; Therefore, although this specification has been described in detail the present invention with reference to each above-mentioned embodiment,, those of ordinary skill in the art should be appreciated that still and can make amendment or be equal to replacement the present invention; And all do not break away from the technical scheme and the improvement thereof of the spirit and scope of invention, and it all should be encompassed in the middle of the claim scope of the present invention.

Claims (4)

1. Shorthorned Epimedium P.E feed addictive, described Shorthorned Epimedium P.E feed addictive comprises stem-leaf extract, the carrier of barrenwort, it is characterized in that: be made up of following formulation by weight ratio: stem-leaf extract 2-4 part of barrenwort, carrier 3-6 part.
2. the preparation method of a Shorthorned Epimedium P.E feed addictive is characterized in that: be divided into following preparation steps:
Step 1, respectively the cauline leaf of raw material barrenwort is chosen only, brachymemma, cleaning;
Step 2, raw material is packed in the alcohol extracting jar, add 75%~95% ethanol of 3~6 times of weight, boiled 3~6 hours, steam pressure is 0.4~0.7MPa, alcohol reflux;
Filter win the respectively filtrate and first filter residue after step 3, the alcohol extracting for the first time; Wherein, first filtrate is reclaimed ethanol by the decompression concentration tank, stop to reclaim until ethanol<60% that reclaims, the continuation of first filtrate concentrate concentrate;
Step 4, first filter residue add 75%~95% ethanol of 3~6 times of weight for the second time, boiled 3~6 hours, and steam pressure 0.4~0.7MPa, alcohol reflux stops to reclaim until ethanol<60% that reclaims, and filters, and gets second filtrate and second filter residue respectively;
Step 5, second filter residue boiled 1 hour once more through 6 times of water gagings, and steam pressure is that 1Mpa handles, and filters, and gets the 3rd filtrate and filter residue respectively, and filter residue discards;
Step 6, concentrate, second filtrate, the 3rd filtrate are mixed and be concentrated into proportion D=1.1~1.3, promptly get medicinal extract;
Step 7, the medicinal extract container of packing into refrigerates in 1~5 ℃ and preserves down;
Step 8, medicinal extract enter spray dryer, 175 ℃ of EATs, and 70~90 ℃ of leaving air temps promptly get Shorthorned Epimedium P.E dry powder;
Step 9, extract dry powder promptly get a kind of Shorthorned Epimedium P.E feed addictive after mixing with the carrier that is fit to.
3. the preparation method of a kind of Shorthorned Epimedium P.E feed addictive according to claim 2 is characterized in that: described carrier is preferably at least a in attapulgite, silica, pine needle meal and the maltodextrin.
4. the preparation method of a kind of Shorthorned Epimedium P.E feed addictive according to claim 2 is characterized in that: described concentrate, first filtrate, second filtrate concentrated is respectively that decompression concentrates or the interlayer concentration tank concentrates.
CN2010190630522A 2010-02-08 2010-02-08 Herba epimedii extract feedstuff additive and preparation method thereof Pending CN102144716A (en)

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Cited By (5)

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CN103222548A (en) * 2013-05-22 2013-07-31 湖南省五季风生物科技有限责任公司 Composite plant extractive feed additive and application thereof
CN103636965A (en) * 2013-11-18 2014-03-19 上海光明荷斯坦牧业有限公司 Bull-pulling feed for breeding bulls
CN105146103A (en) * 2015-09-17 2015-12-16 天津中天精科科技有限公司 Feed additive
CN105146058A (en) * 2015-09-17 2015-12-16 天津中天精科科技有限公司 Feed additive product
CN115380993A (en) * 2022-10-30 2022-11-25 四川合泰新光生物科技有限公司 Clathrate compound containing baohuoside I, composition, preparation method and application thereof

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103222548A (en) * 2013-05-22 2013-07-31 湖南省五季风生物科技有限责任公司 Composite plant extractive feed additive and application thereof
CN103222548B (en) * 2013-05-22 2015-04-01 湖南省五季风生物科技有限责任公司 Composite plant extractive feed additive and application thereof
CN103636965A (en) * 2013-11-18 2014-03-19 上海光明荷斯坦牧业有限公司 Bull-pulling feed for breeding bulls
CN105146103A (en) * 2015-09-17 2015-12-16 天津中天精科科技有限公司 Feed additive
CN105146058A (en) * 2015-09-17 2015-12-16 天津中天精科科技有限公司 Feed additive product
CN115380993A (en) * 2022-10-30 2022-11-25 四川合泰新光生物科技有限公司 Clathrate compound containing baohuoside I, composition, preparation method and application thereof
CN115380993B (en) * 2022-10-30 2023-03-14 四川合泰新光生物科技有限公司 Clathrate compound containing baohuoside I, composition, preparation method and application thereof

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Application publication date: 20110810