CN102143996A - 微球形多孔可生物相容支架及制造该支架的方法和装置 - Google Patents

微球形多孔可生物相容支架及制造该支架的方法和装置 Download PDF

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CN102143996A
CN102143996A CN2009801344899A CN200980134489A CN102143996A CN 102143996 A CN102143996 A CN 102143996A CN 2009801344899 A CN2009801344899 A CN 2009801344899A CN 200980134489 A CN200980134489 A CN 200980134489A CN 102143996 A CN102143996 A CN 102143996A
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poly
particle
ester
microspheres
solvent
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大卫·刘
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/26—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a solid phase from a macromolecular composition or article, e.g. leaching out
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    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
    • A61K51/1255—Granulates, agglomerates, microspheres
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
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    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
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    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
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    • C08J9/28—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices
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    • C08J2201/044—Elimination of an inorganic solid phase
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    • C08J2201/054—Precipitating the polymer by adding a non-solvent or a different solvent
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CN2009801344899A 2008-10-30 2009-10-30 微球形多孔可生物相容支架及制造该支架的方法和装置 Pending CN102143996A (zh)

Applications Claiming Priority (3)

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US19780308P 2008-10-30 2008-10-30
US61/197,803 2008-10-30
PCT/US2009/062744 WO2010062678A2 (en) 2008-10-30 2009-10-30 Micro-spherical porous biocompatible scaffolds and methods and apparatus for fabricating same

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CN102143996A true CN102143996A (zh) 2011-08-03

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US (1) US20110212179A1 (https=)
EP (1) EP2344578A2 (https=)
JP (1) JP2012507562A (https=)
CN (1) CN102143996A (https=)
WO (1) WO2010062678A2 (https=)

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CN103550824A (zh) * 2013-11-01 2014-02-05 南京医科大学附属口腔医院 一种引导骨组织再生的支架的制备方法
CN105175772A (zh) * 2015-10-22 2015-12-23 山西科瑞迪生物科技有限公司 多肽/核苷酸合成用固相载体材料易官能化活性树脂的制备方法
CN105408404A (zh) * 2013-08-09 2016-03-16 金伯利-克拉克环球有限公司 具有多峰孔分布的微粒
CN107304251A (zh) * 2016-04-22 2017-10-31 中国石油化工股份有限公司 用于选择性激光烧结的聚丙烯粉末及其制备
CN108126239A (zh) * 2018-01-02 2018-06-08 四川大学 一种孔道结构可控的明胶细胞支架及其制备方法
CN109106986A (zh) * 2018-09-14 2019-01-01 广州润虹医药科技股份有限公司 一种药物控释磷酸钙骨水泥复合微球、其制备方法及应用
CN109833509A (zh) * 2019-01-18 2019-06-04 太阳雨林（厦门）生物医药有限公司 一种多重缓释血管栓塞载药组合物
CN110177583A (zh) * 2017-01-31 2019-08-27 金伯利-克拉克环球有限公司 多孔聚酯材料
CN118406273A (zh) * 2024-05-29 2024-07-30 广东安拓普聚合物科技股份有限公司 一种医用导管用tpu材料及其生产工艺

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JP2017505138A (ja) 2014-02-05 2017-02-16 モダン メドー インコーポレイテッド 培養筋細胞から形成される乾燥食品
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JP6692834B2 (ja) 2015-02-09 2020-05-13 スリングショット バイオサイエンシーズ， インコーポレイテッド 調整可能な光学特性を有するヒドロゲル粒子およびその使用の方法
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