CN102143756A - 来自乳杆菌属细菌的免疫调节提取物及其制备及使用方法 - Google Patents

来自乳杆菌属细菌的免疫调节提取物及其制备及使用方法 Download PDF

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Publication number
CN102143756A
CN102143756A CN2008801309602A CN200880130960A CN102143756A CN 102143756 A CN102143756 A CN 102143756A CN 2008801309602 A CN2008801309602 A CN 2008801309602A CN 200880130960 A CN200880130960 A CN 200880130960A CN 102143756 A CN102143756 A CN 102143756A
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extract
lactobacillus
hours
cell
strain
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J·A·鲍尔
M·萨尔瓦尼
J-P·L·维格鲁
L·L·G·沙尔维
C·夏瓦洛利
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OM Pharma SA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/225—Lactobacillus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Otolaryngology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN2008801309602A 2008-09-04 2008-09-04 来自乳杆菌属细菌的免疫调节提取物及其制备及使用方法 Pending CN102143756A (zh)

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PCT/US2008/010350 WO2010027344A1 (en) 2008-09-04 2008-09-04 Immunomodulatory extracts from lactobacillus bacteria and methods of manufacturing and use thereof

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JP (1) JP2012502026A (pt)
KR (1) KR20110051268A (pt)
CN (1) CN102143756A (pt)
AU (1) AU2008361375B2 (pt)
BR (1) BRPI0822997A2 (pt)
CA (1) CA2733249A1 (pt)
IL (1) IL211041A0 (pt)
MX (1) MX2011002080A (pt)
RU (1) RU2500412C2 (pt)
WO (1) WO2010027344A1 (pt)
ZA (1) ZA201100899B (pt)

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CN103798392A (zh) * 2014-03-07 2014-05-21 内蒙古伊利实业集团股份有限公司 具有缓解咽喉部炎症功效的益生菌食品组合物及食品
TWI509069B (zh) * 2013-07-12 2015-11-21 Univ Nat Yang Ming 具有免疫調節及抗過敏作用的乳酸菌
CN109007842A (zh) * 2018-10-29 2018-12-18 广州普维君健药业有限公司 具有防治过敏功效的益生菌组合物及其应用
CN109628359A (zh) * 2019-02-22 2019-04-16 江南大学 一株可缓解过敏性哮喘的罗伊氏乳杆菌及其应用
CN110013490A (zh) * 2018-01-09 2019-07-16 柯顺议 益生菌组合物及其用途
CN110643541A (zh) * 2019-10-25 2020-01-03 江南大学 一株可调节过敏性哮喘Th2/Th1平衡的干酪乳杆菌及其应用
CN111053789A (zh) * 2019-11-26 2020-04-24 湖南营养树生物科技有限公司 调节免疫系统的方法和组合物
CN111548961A (zh) * 2020-05-15 2020-08-18 郑州和合生物工程技术有限公司 改善过敏性疾病的益生菌组合物、益生菌组合物菌粉及制备方法，应用
CN111991428A (zh) * 2020-06-12 2020-11-27 郑州和合生物工程技术有限公司 一种具有改善哮喘作用的益生菌组合物及其制备方法
CN112469403A (zh) * 2018-06-07 2021-03-09 国立大学法人金泽大学 肾损伤的预防或治疗用的药物组合物
CN112469404A (zh) * 2018-06-07 2021-03-09 国立大学法人金泽大学 肾损伤的预防或治疗用的药物组合物
CN113840615A (zh) * 2019-03-14 2021-12-24 Om药物公司 制备稳定细菌提取物的方法及其作为药物的用途
US11291698B2 (en) 2018-05-09 2022-04-05 Kobiolabs, Inc. Lactobacillus paracasei strain and use thereof
RU2790297C2 (ru) * 2018-05-09 2023-02-16 КоБиоЛабс, Инк Штамм lactobacillus paracasei и его применение

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EP2670415A4 (en) * 2011-02-02 2014-11-26 Justbio Inc FUNCTIONAL FOODS AND BEVERAGES WITH SYNERGISTIC PROPERTIES FOR THE PROMOTION OF HOMEOSTASIS
JP6014652B2 (ja) * 2011-03-29 2016-10-25 ネステク ソシエテ アノニム Ｄ−乳酸産生が欠損し、保存期間が改善した、ラクトバチルスジョンソニー（Ｌａｃｔｏｂａｃｉｌｌｕｓｊｏｈｎｓｏｎｉｉ）ＣＮＣＭＩ−１２２５株の天然変異体
BR112013024831A2 (pt) * 2011-03-29 2016-12-20 Nestec Sa derivado natural da cepa cncm i-1225 de lactobacillus johnsonii, deficiente na produção de ácido d=láctico e com um perfil imunológico mais incrementado
US20130022586A1 (en) 2011-07-21 2013-01-24 James Versalovic Production and use of bacterial histamine
JP6632802B2 (ja) 2012-01-16 2020-01-22 マッケンナ，エリザベス 肝疾患及び肝障害を治療するための組成物及び方法
WO2014047588A1 (en) 2012-09-21 2014-03-27 Elizabeth Mckenna Naturally occurring cpg oligonucleotide compositions and therapeutic applications thereof
JP6821643B2 (ja) * 2013-09-26 2021-01-27 雪印メグミルク株式会社 免疫疾患予防剤
JP6491422B2 (ja) * 2013-09-26 2019-03-27 雪印メグミルク株式会社 免疫疾患予防剤
KR101627806B1 (ko) * 2014-06-23 2016-06-07 한국식품연구원 락토바실러스 속 균주의 면역증강 활성을 증가시키는 배양 방법
JP6940305B2 (ja) * 2017-06-01 2021-09-22 株式会社明治 チーズ風味素材の製造方法
KR102335710B1 (ko) 2017-10-31 2021-12-07 (주)아모레퍼시픽 유산균 유래의 세포밖 베지클을 포함하는 면역조절용 조성물
KR102156829B1 (ko) * 2019-02-22 2020-09-18 가톨릭대학교 산학협력단 마이크로바이옴 혼합물을 포함하는 면역 질환의 예방 및 치료용 조성물
EP4084784A4 (en) * 2020-01-13 2024-01-17 Univ Monash COMPOSITIONS AND METHODS
CN112057479B (zh) * 2020-11-16 2021-02-12 河北一然生物科技有限公司 一种能够缓解抗生素引起腹泻的益生菌组合物
KR102424594B1 (ko) * 2020-11-30 2022-07-25 파이토지노믹스 주식회사 항염 활성 및 유해 미생물에 대한 항균 활성을 가지는 락토바실러스 퍼멘텀 okbl-l.fe 1 균주 및 이의 용도
KR20230001127A (ko) 2021-06-28 2023-01-04 농업회사법인 산청바이오진생마을 주식회사 새싹 인삼 라떼 제조방법
KR20230131450A (ko) * 2022-03-03 2023-09-13 한국생명공학연구원 N-카바밀-l-글루탐산을 포함하는 염증성 질환의 치료용 조성물
CN114774302B (zh) * 2022-03-09 2023-06-16 善恩康生物科技（苏州）有限公司 植物乳杆菌cqpc02在制备用于预防和/或治疗狼疮性肾炎的产品中的应用

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Publication number Priority date Publication date Assignee Title
CH532903A (fr) * 1971-06-25 1973-01-31 Nestle Sa Procédé d'extraction de protéines à partir de cellules de microorganismes
JP3004890B2 (ja) * 1995-03-28 2000-01-31 雪印乳業株式会社 病原体感染防御剤
EP1239032A1 (en) * 2001-03-02 2002-09-11 Société des Produits Nestlé S.A. Lactic acid bacteria as agents for treating and preventing allergy
PE20030274A1 (es) * 2001-07-26 2003-05-08 Alimentary Health Ltd Cepas de lactobacillus salivarius
RU2302458C2 (ru) * 2001-07-26 2007-07-10 Элиментери Хелс Лимитед Пробиотический штамм lactobacillus salivarius (варианты), пробиотический препарат на их основе и способ лечения или предупреждения с использованием штаммов lactobacillus salivarius
US7025998B2 (en) * 2003-05-30 2006-04-11 Rotta Research Laboratorium S.P.A. Phytoestrogens and probiotic for women's health
EP1722804B1 (en) * 2004-03-04 2015-01-21 E-L Management Corp. Skin treatment method with lactobacillus extract
CA2609617C (en) * 2005-05-31 2014-07-08 The Iams Company Feline probiotic lactobacilli
JP2007269737A (ja) * 2006-03-31 2007-10-18 Morinaga Milk Ind Co Ltd インターロイキン産生調節剤、該インターロイキン産生調節剤を含む医薬組成物及び飲食品、並びにその製造方法
JP5019961B2 (ja) * 2006-06-26 2012-09-05 株式会社ヤクルト本社 インターロイキン１０産生促進剤

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI509069B (zh) * 2013-07-12 2015-11-21 Univ Nat Yang Ming 具有免疫調節及抗過敏作用的乳酸菌
CN103798392A (zh) * 2014-03-07 2014-05-21 内蒙古伊利实业集团股份有限公司 具有缓解咽喉部炎症功效的益生菌食品组合物及食品
CN104957260A (zh) * 2014-03-07 2015-10-07 内蒙古伊利实业集团股份有限公司 具有缓解咽喉部炎症功效的益生菌食品组合物及食品
CN103798392B (zh) * 2014-03-07 2015-12-30 内蒙古伊利实业集团股份有限公司 具有缓解咽喉部炎症功效的益生菌食品组合物及食品
CN104957260B (zh) * 2014-03-07 2018-07-24 内蒙古伊利实业集团股份有限公司 具有缓解咽喉部炎症功效的益生菌食品组合物及食品
CN110013490A (zh) * 2018-01-09 2019-07-16 柯顺议 益生菌组合物及其用途
US11992511B2 (en) 2018-05-09 2024-05-28 Kobiolabs, Inc. Lactobacillus paracasei strain and use thereof
RU2790297C9 (ru) * 2018-05-09 2023-04-24 КоБиоЛабс, Инк Штамм lactobacillus paracasei и его применение
RU2790297C2 (ru) * 2018-05-09 2023-02-16 КоБиоЛабс, Инк Штамм lactobacillus paracasei и его применение
US11291698B2 (en) 2018-05-09 2022-04-05 Kobiolabs, Inc. Lactobacillus paracasei strain and use thereof
CN112469403A (zh) * 2018-06-07 2021-03-09 国立大学法人金泽大学 肾损伤的预防或治疗用的药物组合物
CN112469404A (zh) * 2018-06-07 2021-03-09 国立大学法人金泽大学 肾损伤的预防或治疗用的药物组合物
CN109007842A (zh) * 2018-10-29 2018-12-18 广州普维君健药业有限公司 具有防治过敏功效的益生菌组合物及其应用
CN109628359A (zh) * 2019-02-22 2019-04-16 江南大学 一株可缓解过敏性哮喘的罗伊氏乳杆菌及其应用
CN113840615A (zh) * 2019-03-14 2021-12-24 Om药物公司 制备稳定细菌提取物的方法及其作为药物的用途
CN110643541A (zh) * 2019-10-25 2020-01-03 江南大学 一株可调节过敏性哮喘Th2/Th1平衡的干酪乳杆菌及其应用
CN111053789A (zh) * 2019-11-26 2020-04-24 湖南营养树生物科技有限公司 调节免疫系统的方法和组合物
CN111548961A (zh) * 2020-05-15 2020-08-18 郑州和合生物工程技术有限公司 改善过敏性疾病的益生菌组合物、益生菌组合物菌粉及制备方法，应用
CN111991428A (zh) * 2020-06-12 2020-11-27 郑州和合生物工程技术有限公司 一种具有改善哮喘作用的益生菌组合物及其制备方法

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CA2733249A1 (en) 2010-03-11
BRPI0822997A2 (pt) 2015-06-23
IL211041A0 (en) 2011-04-28
MX2011002080A (es) 2011-03-29
JP2012502026A (ja) 2012-01-26
KR20110051268A (ko) 2011-05-17
RU2500412C2 (ru) 2013-12-10
WO2010027344A1 (en) 2010-03-11
ZA201100899B (en) 2012-05-30
RU2011112781A (ru) 2012-10-10
AU2008361375B2 (en) 2014-05-22
AU2008361375A1 (en) 2010-03-11

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