CN102106450A - Efficient green anti-coccidiosis feed for meat chickens and preparation method thereof - Google Patents
Efficient green anti-coccidiosis feed for meat chickens and preparation method thereof Download PDFInfo
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Abstract
The invention discloses an efficient green anti-coccidiosis feed for meat chickens and a preparation method and application thereof. The feed consists of corktree bark, baikal skullcap root, golden thread, dock root, licorice root, garden burnet root, betaine, vitamin A, vitamin K3, calcium hydrogen phosphate, potassium iodide and sodium selenite. The method comprises the following steps of: crushing the Chinese medicaments, sieving the powder with a sieve of 60 meshes, weighing the powder in a weight ratio, mixing for 5 to 10 minutes with an efficient mixer, packing with bags, wherein the mixing uniformity requirement of the mixer comprises that the variation coefficient of the uniformity is not more than 5 percent. The production process for the efficient green anti-coccidiosis feed is simple and easily operated and mastered. The feed is convenient to use and remarkable in effect; the coccidiosis incidence rate of the meat chickens can be reduced to less than 10 percent; and the feed can provide the requirements of the meat chickens on vitamins, trace elements and mineral in the growth and development processes at the same time of improving the coccidiosis resistance of the meat chickens, and has popularization and application value.
Description
Technical field
The invention belongs to field of feed additive technology, special-purpose coccidiosis medicine of particularly a kind of fryer and preparation method thereof and application.
Background technology
Chicken coccidiasis is to endanger one of the most serious disease in the poultry husbandry, particularly in the area of temperature height, high humidity, helps growing of coccidian oocyst, usually is that fulminant is popular.Global-worm illness often causes the chick morbidity of 15-50 age in days, and the death rate is up to 80%, and the chick growth of recovering seriously lags behind, and resistance reduces, and easily suffers from other eqpidemic disease.The coccidia multiparasitization of most of kinds causes the enteron aisle pathology in enteron aisle.Clinical manifestation is mainly with hemorrhagic enteritis, bloody flux, and the high incidence of chick and the death rate are feature.It descends the poultry husbandry productivity, and productivity effect reduces, and harmfulness is very big.According to incompletely statistics, at present the incidence of disease of China's fryer global-worm illness up to 70%.Do not having as yet under the situation of anti-preferably ball vaccine at present, in feed, adding the effective measures that the coccidiosis medicine just becomes prevention and control global-worm illness.
At present, in the livestock and poultry cultivation process, use a lot of inputs such as feed, veterinary drug.Can select different inputs at different needs.Along with the expansion that the intensification scale is raised, the increase of cultivation density, the incidence of disease of global-worm illness is becoming ascendant trend.The effective way of prevention and treatment chicken coccidiasis is the omnidistance chemical synthesis class anticoccidial feed that adds in daily ration, this is the major measure of preventing and treating fryer global-worm illness now, but usually occur that curative effect is not good enough, drug resistance increases, the residual also ubiquity of problem such as exceed standard of medicine.In daily ration, add fryer global-worm illness Chinese herbal medicine evident in efficacy is prevented and treated this disease, can greatly overcome the residual problem of medicine.China Chinese medicine medicine source is extensive, aboundresources, variously all can suit measures to local conditions, gather materials on the spot, make full use of the advantage of local Chinese material medicine resource, under the modern medicine and pharmacology guide of theory, use Chinese veterinarian's traditional theory and modern biotechnology, be applied in the animal and fowl fodder after the processing processing through science, be subjected to general attention.Obtain maximum economic benefits with minimum input, be well worth doing.In view of an urgent demand at present both at home and abroad solves residual in meat that abuse of antibiotics, chemical synthetic drug and hormone drugs bring, egg, the milk livestock products, drug resistance, toxic and side effect, and to problems such as human health work the mischief, it is difficult for producing advantages such as drug resistance but Chinese herbal medicine has the little and worm of killing of toxic and side effect, strengthen body immunity function, growth promotion, coccidia, this has broad prospects with regard to the research and development that disclose Chinese medicine anticoccidial preparation.
Summary of the invention
Technical problem to be solved by this invention is: a kind of fryer efficient green anticoccidial feed is provided.Can resist fryer global-worm illness, can solve the residual problem of medicine again, replenish in the growth of meat chicken growth course needs simultaneously vitamin, trace element and mineral matter.The fryer global-worm illness incidence of disease is reduced to below 10%.The invention provides following technical scheme for achieving the above object:
Fryer efficient green anticoccidial feed is characterized in that being made up of following materials based on weight:
200～300 parts of 90～120 parts of roots of large-flowered skullcap of golden cypress
70～150 parts of 80～130 parts of Rumex madaios of the coptis
80～140 parts of 80～160 portions of garden burnets of Radix Glycyrrhizae
0.25～0.35 part of 15～50 parts of vitamin A of betaine
20～30 parts of 0.01～0.03 part of calcium monohydrogen phosphates of prokeyvit
0.10～0.50 part of 0.10～0.30 part of sodium selenite of KI.
Fryer efficient green anticoccidial feed of the present invention, optimization formula is:
200～280 parts of 100～120 parts of roots of large-flowered skullcap of golden cypress
80～150 parts of 90～130 parts of Rumex madaios of the coptis
80～120 parts of 100～160 portions of garden burnets of Radix Glycyrrhizae
0.25～0.3 part of 15～30 parts of vitamin A of betaine
20～30 parts of 0.01～0.02 part of calcium monohydrogen phosphates of prokeyvit
0.10～0.40 part of 0.10～0.20 part of sodium selenite of KI.
Fryer efficient green anticoccidial feed of the present invention, optimum formula is:
240 parts of 100 parts of roots of large-flowered skullcap of golden cypress
90 parts of 100 parts of Rumex madaios of the coptis
110 parts of 120 portions of garden burnets of Radix Glycyrrhizae
0.27 part of 23 parts of vitamin A of betaine
Vitamin K
30.015 20 parts of part calcium monohydrogen phosphates
0.20 part of 0.10 part of sodium selenite of KI
The preparation method of fryer efficient green anticoccidial feed of the present invention is characterized in that elder generation with after above-mentioned Chinese medicine pulverizing, crossing 60 mesh sieves, claims to join by above-mentioned part by weight again, after efficient mixer mixes 5～10 minutes, can be packaged into bag; Wherein the requirement of the mixture homogeneity of mixer is: the coefficient of variation of the uniformity should be not more than 5%.
The coefficient of variation of the uniformity that mixer of the present invention mixes should be not more than 5%, mainly is to meet in the feed product quality standard of China's promulgation regulation to the processing index in order to ensure prepared product.The leading indicator of weighing the feed product quality comprises mixture homogeneity and grinding particle size.The mixture homogeneity coefficient of variation of premixed feed should be not more than 7%, and grinding particle size required 60 mesh sieves.
The present invention further discloses the application of fryer efficient green anticoccidial feed aspect preparation treatment chicken coccidiasis medicine, the addition of its fryer efficient green anticoccidial feed is the 0.1-0.5% (percentage by weight) of common chicken feed.Its anticoccidial index reached 178-179.7 when the anticoccidial feed that in common chicken feed, adds 0.5%.Effectively controlled the incidence of disease of 15-50 Japanese instar chickling.
The characteristic of each traditional Chinese medicine ingredients is as follows in the fryer efficient green anticoccidial feed of the present invention:
Golden cypress is the bark of rutaceae golden cypress or wampee.The golden cypress antibiotic effective ingredient is a jamaicin, thus its pharmacological action and coptis broadly similar, but content is low than the coptis.In vitro test to staphylococcus aureus, pneumococcus, corynebacterium diphtheriae, Streptococcus viridans, shigella dysenteriae (except Song Nei Shi), hemolytic streptococcus, meningococcus, comma bacillus, bacillus anthracis all effectively or stronger inhibitory action arranged;
The root of large-flowered skullcap is the dry root of the labiate root of large-flowered skullcap.Active ingredient mainly is flavone compound, another name Radix Scutellariae, tsuchikane tea root.Wild in the mountain top, dry on the sunny side place such as hillside, border, roadside.Its antimicrobial spectrum is wider, and various bacteria, dermatophyte, Leptospira etc. are all had inhibitory action.
The coptis is the dry rhizome that the ranunculaceae plant coptis, the triangle leaf coptis or cloud connect.The coptis contains multiple alkaloids such as jamaicin, coptisine, and other contains compositions such as obakunone, obakulactone.Resisting pathogenic microbes and antiprotozoan effect are remarkable.In vitro test proves that the coptis all has stronger antibacterial action to hemolytic streptococcus, meningococcus, Diplococcus pneumopniae, comma bacillus, bacillus anthracis and staphylococcus aureus.
Rumex madaio is a Rumex gmelini Turcz, is used as medicine with root and leaf.Root contains anthraquinones.Has effect clearing heat and detoxicating, stop blooding, the dispel stasis of blood, defaecation, desinsection.Be used for lung abscess, hemoptysis of pulmonary tuberculosis, bleeding from five sense organs or subcutaneous tissue, Japanese Type-B encephalitis, acute and chronic hepatitis, constipation; Traumatic injury is controlled in external application, burn and scald, carbuncle furuncle poison, mumps, scabies, eczema, dermatitis.
Radix Glycyrrhizae is root and the rhizome of pulse family herbaceos perennial Radix Glycyrrhizae.Main product is in the NORTHWEST CHINA each province.Put down in writing in the Shennong's Herbal before more than 2,000 years: " Radix Glycyrrhizae cures mainly vital organs of the human body fever and chills perverse trend, hard muscles and bones, and longue meat, times strength, metal-inflicted wound disappears, and separates ten thousand poison ... ".The tradition traditional Chinese medical science thinks that Radix Glycyrrhizae has effects such as tonifying middle-Jiao and Qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, the mitigation property of medicine.
The burnet herbaceos perennial.It is about 17% that root contains tannin, triterpenoid saponin 2.5～4.0%.Have blood on the cool blood, clearing heat and detoxicating effect.Control haematemesis, bleeding from five sense organs or subcutaneous tissue, bloody flux, uterine bleeding, intestines wind, anal fistula, carbuncle is swollen, eczema, metal-inflicted wound, burn.
Betaine claims trimethylglycine again, is a kind of quaternary amine type alkaloid, extensively is formed in the bodies of aminal and plant, especially with the highest in the beet molasses.Betaine has the palatability that can partly replace methionine and choline, promotion fat metabolism, raising lean meat percentage, change feed, the curative effect that improves anticoccidial drug and diarrhoea medicine.The betaine that from natural microorganism, animals and plants, extracts, very in vogue abroad as the additive of pig, chicken, aquatic products.
The present invention further discloses the application of the special-purpose coccidiosis medicine of fryer aspect preparation fryer anticoccidial feed addictive.The addition of its fryer efficient green anticoccidial feed is the 0.1-0.5% (percentage by weight) of common chicken feed.Its anticoccidial index reached 178-179.7 when the anticoccidial feed that in common chicken feed, adds 0.5%.Effectively controlled the incidence of disease of 15-50 Japanese instar chickling.The pharmacological verification result of the test of effect, growth of meat chicken growth course that the present invention reduces the fryer global-worm illness incidence of disease is as follows:
Method: the method with reference to the analysis anticoccidial effect of U.S. Merck company introduction is tested meat son.Anticoccidial index (ACI)=(the relative weight gain rate+survival rate) * 100-(pathology value+egg capsule value).According to anticoccidial drug effect evaluation standard, ACI≤120 are invalid, and ACI 120--160 is medium effective, and ACI 160-180 is good, and ACI＞180 are outstanding.
Step:
(1) newly goes out 500 of shell AA meat chicks to purchasing, under the environment of strict sterilization, raise, the special-purpose broiler fodder (not containing coccidiostat) of feeding, drink clean running water, raise to 13 ages in days by normal feeding and management program, the true non-ball worm of stool examination is infected, and every chicken infects 8 * 10 with indenting ball through crop
4Individual coccidian oocyst carries out infection experiment.
(2) from the chicken group, select 180 chickens that body weight is close, coccidia has been infected in stool examination, be divided into 3 groups at random, 60 every group.Be respectively: not administration group (blank group), with other anticoccidial goods group (control group) and interpolation this fryer efficient green anticoccidial feed group (test group).Control group is pressed product description and is used, and test group is admixed these goods in the feed in 0.3% ratio, feeds to delivering for sale.
Experimental result:
| Group | Blank group | Control group | Test group |
| Anticoccidial Index A CI | 0 | 160 | 178 |
Because the main component of this fryer efficient green anticoccidial feed is a Chinese medicine, China does not exist Chinese medicine that there is the residual problem of medicine in chicken not to the regulation of Chinese medicine off-drug period at present.
The good effect of fryer efficient green anticoccidial feed of the present invention is:
1. production technology is simple, and grasp easy to operate is easy to use, when improving the fryer coccidiosis, can provide fryer needs to vitamin, trace element and mineral matter in growth and development process again.
2. this feed can directly add in the broiler fodder in the ratio of 0.1-0.5% and uses, and must mix.
3. packing specification can be adjusted arbitrarily as required.
4. the function that has vitamin, trace element and the mineral matter of additional fryer needs.
5. effect is remarkable, and the incidence of disease of fryer global-worm illness is reduced to below 10%.
The specific embodiment:
In order to explain enforcement of the present invention more fully, provide the preparation embodiment of fryer efficient green anticoccidial feed.These embodiments only are to explain rather than limit the scope of the invention.Wherein raw material and the reagent that is adopted in the test all has commercially available.
Embodiment 1:
Fryer efficient green anticoccidial feed, prescription is by golden cypress, the root of large-flowered skullcap, the coptis, Rumex madaio, Radix Glycyrrhizae, garden burnet, betaine, vitamin A, vitamin K
3, calcium monohydrogen phosphate, KI and sodium selenite form.With after above-mentioned Chinese medicine pulverizing, crossing 60 mesh sieves, claim to join by above-mentioned part by weight more earlier, after efficient mixer mixes 5～10 minutes, by using the difference requirements to be packaged into bag.Fill a prescription by weight:
90 kilograms of golden cypresses; 230 kilograms of the roots of large-flowered skullcap; Coptis double centner; 80 kilograms of Rumex madaios; The Radix Glycyrrhizae double centner; The garden burnet double centner; 25 kilograms of betaines; 0.30 kilogram of vitamin A; Vitamin K
30.02 kilogram; 25 kilograms of calcium monohydrogen phosphates; 0.15 kilogram of KI; 0.20 kilogram of sodium selenite.
With after above-mentioned Chinese medicine pulverizing, crossing 60 mesh sieves, claim to join by above-mentioned part by weight more earlier, after efficient mixer mixes 5～10 minutes, according to actual operating position, the packaging bag enclosing of packing into.The mixture homogeneity of mixer requires: the coefficient of variation of the uniformity should be not more than 5%.
Embodiment 2:
Fill a prescription by weight
110 kilograms of golden cypresses; 250 kilograms of the roots of large-flowered skullcap; Coptis double centner; 80 kilograms of Rumex madaios; 90 kilograms in Radix Glycyrrhizae; 90 kilograms of garden burnets; 20 kilograms of betaines; 0.25 kilogram of vitamin A; Vitamin K
30.015 kilogram; 21 kilograms of calcium monohydrogen phosphates; 0.15 kilogram of KI; 0.10 kilogram of sodium selenite.
With after above-mentioned Chinese medicine pulverizing, crossing 60 mesh sieves, claim to join by above-mentioned part by weight more earlier, after efficient mixer mixes 5～10 minutes, according to actual operating position, the packaging bag enclosing of packing into.The mixture homogeneity of mixer requires: the coefficient of variation of the uniformity should be not more than 5%.
Embodiment 3: fill a prescription by weight:
The golden cypress double centner; 240 kilograms of the roots of large-flowered skullcap; Coptis double centner; 90 kilograms of Rumex madaios; 120 kilograms in Radix Glycyrrhizae; 110 kilograms of garden burnets; 23 kilograms of betaines; 0.27 kilogram of vitamin A; Vitamin K
30.015 kilogram; 20 kilograms of calcium monohydrogen phosphates; 0.15 kilogram of KI; 0.25 kilogram of sodium selenite.
With after above-mentioned Chinese medicine pulverizing, crossing 60 mesh sieves, claim to join by above-mentioned part by weight more earlier, after efficient mixer mixes 5～10 minutes, according to actual operating position, the packaging bag enclosing of packing into.The mixture homogeneity of mixer requires: the coefficient of variation of the uniformity should be not more than 5%, meets the processing index request of stipulating in the feed product quality standard of China's promulgation.
Embodiment 4:
The concrete feeding experiment and the experiment effect of fryer efficient green anticoccidial feed
1 material method
1.1 the raw material of selecting for use: the golden cypress root of large-flowered skullcap, the coptis, Rumex madaio, Radix Glycyrrhizae, garden burnet, betaine, vitamin A, prokeyvit, calcium monohydrogen phosphate, KI, sodium selenite all have commercially available.
1.2 test chicken: select just to have gone out 600 of the AA chickens of shell, carry out immunity by the normal immune programme for children of fryer.
1.3 basal diet: see Table 1
Table 1
1.4 control group additive: 0.4% Amprolium hydrochloride additive.
2 experimental design
2.1 grouping
From the chicken group, select 300 chickens that body weight is close, coccidia has been infected in stool examination, be divided into 3 groups at random, 100 every group.
First group is blank group, the basal diet of only feeding.
Second group is control group, the basal diet of feeding+0.4% Amprolium hydrochloride additive.
The 3rd group is test group, the basal diet of feeding+fryer efficient green anticoccidial feed 0.2% (embodiment 2).
2.2 test data sheet
Duration of test record each group morbidity and death condition, record feed consumption rate every day finishes test in the time of 49 days, weigh, and calculates material anharmonic ratio and death rate.
3 result of the tests: see Table 2.
Each processed group production performance of table 2 experiment fryer is (%) relatively
| Index | Blank group | Control group | Test group |
| Courageous and upright enteritis, | 81 | 19 | 18 |
| Bloody flux, | 75 | 16 | 16 |
| The death rate | 77 | 9 | 9 |
Anticoccidial index 0 168 170
Show that by table 2 the fryer efficient green anticoccidial feed of experimental design obviously is better than blank group aspect production performance, but close with the control group effect, for this this seminar adjusts prescription: (seeing embodiment 3) experimentizes again, the results are shown in Table 3.
Each processed group production performance of table 3 test chicken relatively
| Index | Blank group | Control group | Test group |
| Courageous and upright enteritis, | 80 | 19 | 16 |
| Bloody flux | 75 | 17 | 11 |
| The death rate | 74 | 9 | 7 |
| The anticoccidial index | 0 | 170 | 179 |
3 brief summaries
1. the anticoccidial effect of test group is significantly higher than blank group, a little more than control group.Anticoccidial effect reaches good level.The anticoccidial drug of present domestic use mainly is the Western medicine of chemical synthesis, though these medicines have been brought into play certain effect, because coccidia has unique drug resistance generation mechanism, after using a period of time, all can cause polypide to produce drug resistance, cause the prevention effect of many anticoccidial drugs significantly to reduce, make the prevention result of treatment is not good or the failure.These goods mainly are made up of Chinese medicine, and Chinese medicine is natural plants, does not have the drug resistance problem.
2. because Western medicine is very easy to remain in the chicken, influence the quality of meat, harm humans healthy, and China's " feeding of broiler veterinary drug usage criteria " allows to use Chinese medicine, it there is not the regulation of off-drug period, so, use these goods, there is not the residual problem of medicine of poultry, do not influence the quality of poultry, guarantee the quality safety of poultry, met the requirement that current people grow with each passing day to " green " food
The above, it only is preferred embodiment of the present invention, be not that the present invention is done any pro forma restriction, every foundation technical spirit of the present invention all still belongs in the scope of technical solution of the present invention any simple modification, equivalent variations and modification that above embodiment did.
Claims (7)
1. fryer efficient green anticoccidial feed is characterized in that being made up of following materials based on weight:
200～300 parts of 90～120 parts of roots of large-flowered skullcap of golden cypress
70～150 parts of 80～130 parts of Rumex madaios of the coptis
80～140 parts of 80～160 portions of garden burnets of Radix Glycyrrhizae
0.25～0.35 part of 15～50 parts of vitamin A of betaine
20～30 parts of 0.01～0.03 part of calcium monohydrogen phosphates of prokeyvit
0.10～0.50 part of 0.10～0.30 part of sodium selenite of KI.
2. the described fryer efficient green of claim 1 anticoccidial feed is characterized in that being made up of following materials based on weight:
200～280 parts of 100～120 parts of roots of large-flowered skullcap of golden cypress
80～150 parts of 90～130 parts of Rumex madaios of the coptis
80～120 parts of 100～160 portions of garden burnets of Radix Glycyrrhizae
0.25～0.3 part of 15～30 parts of vitamin A of betaine
20～30 parts of 30.01～0.02 parts of calcium monohydrogen phosphates of vitamin K
0.10～0.40 part of 0.10～0.20 part of sodium selenite of KI.
3. the described fryer efficient green of claim 1 anticoccidial feed is characterized in that being made up of following materials based on weight:
240 parts of 100 parts of roots of large-flowered skullcap of golden cypress
90 parts of 100 parts of Rumex madaios of the coptis
110 parts of 120 portions of garden burnets of Radix Glycyrrhizae
0.27 part of 23 parts of vitamin A of betaine
20 parts of 0.015 part of calcium monohydrogen phosphates of prokeyvit
0.20 part of 0.10 part of sodium selenite of KI.
4. each described fryer efficient green anticoccidial feed of claim 1-3, the application aspect preparation fryer anticoccidial feed addictive.
5. the described application of claim 4, the addition of wherein said fryer efficient green anticoccidial feed is the 0.1-0.5% (percentage by weight) of common chicken feed.
6. each described fryer efficient green anticoccidial feed of claim 1-3, fryer wherein comprises chick or adult fryer; Described chick is meant purebred meat chick, hybridization meat chick; Adult fryer is meant adult fryer, meat kind chicken.
7. the preparation method of any described fryer efficient green anticoccidial feed of claim 1-3, it is characterized in that earlier with after above-mentioned Chinese medicine pulverizing, crossing 60 mesh sieves, claim to join by above-mentioned part by weight again, after efficient mixer mixes 5～10 minutes, can be packaged into bag; Wherein the requirement of the mixture homogeneity of mixer is: the coefficient of variation of the uniformity should be not more than 5%.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103583886A (en) * | 2013-10-22 | 2014-02-19 | 王四荣 | Chick feed for preventing globidiosis |
| CN104686840A (en) * | 2015-02-13 | 2015-06-10 | 高深 | Antibiotic-free chicken feed additive and preparation method thereof |
| CN106578636A (en) * | 2016-12-13 | 2017-04-26 | 重庆市长寿区标杆养鸡股份合作社 | Chick feed |
| CN110100950A (en) * | 2019-06-19 | 2019-08-09 | 山东省农业科学院家禽研究所 | A kind of composite feed additive of substitute antibiotics prevention and treatment chicken coccidiasis |
-
2009
- 2009-12-28 CN CN2009102451160A patent/CN102106450A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103583886A (en) * | 2013-10-22 | 2014-02-19 | 王四荣 | Chick feed for preventing globidiosis |
| CN103583886B (en) * | 2013-10-22 | 2015-11-18 | 王四荣 | A kind of chicken feed preventing global-worm illness |
| CN104686840A (en) * | 2015-02-13 | 2015-06-10 | 高深 | Antibiotic-free chicken feed additive and preparation method thereof |
| CN106578636A (en) * | 2016-12-13 | 2017-04-26 | 重庆市长寿区标杆养鸡股份合作社 | Chick feed |
| CN110100950A (en) * | 2019-06-19 | 2019-08-09 | 山东省农业科学院家禽研究所 | A kind of composite feed additive of substitute antibiotics prevention and treatment chicken coccidiasis |
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Application publication date: 20110629 |