CN102085382A - 一种眼科专用杀菌型医用超声耦合剂及制备方法 - Google Patents
一种眼科专用杀菌型医用超声耦合剂及制备方法 Download PDFInfo
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- CN102085382A CN102085382A CN 201110031744 CN201110031744A CN102085382A CN 102085382 A CN102085382 A CN 102085382A CN 201110031744 CN201110031744 CN 201110031744 CN 201110031744 A CN201110031744 A CN 201110031744A CN 102085382 A CN102085382 A CN 102085382A
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- couplant
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- 238000002360 preparation method Methods 0.000 title claims abstract description 23
- 238000002604 ultrasonography Methods 0.000 title abstract description 7
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- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims abstract description 20
- 238000003756 stirring Methods 0.000 claims abstract description 16
- 239000007822 coupling agent Substances 0.000 claims description 54
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- 239000000080 wetting agent Substances 0.000 claims description 16
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 14
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 14
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 12
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- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 9
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- 239000002131 composite material Substances 0.000 claims description 7
- 229940071826 hydroxyethyl cellulose Drugs 0.000 claims description 7
- 239000001103 potassium chloride Substances 0.000 claims description 7
- 235000011164 potassium chloride Nutrition 0.000 claims description 7
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- 229920003169 water-soluble polymer Polymers 0.000 claims description 6
- GAWIXWVDTYZWAW-UHFFFAOYSA-N C[CH]O Chemical group C[CH]O GAWIXWVDTYZWAW-UHFFFAOYSA-N 0.000 claims description 4
- 239000002202 Polyethylene glycol Substances 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 230000003647 oxidation Effects 0.000 claims description 4
- 238000007254 oxidation reaction Methods 0.000 claims description 4
- 229920001223 polyethylene glycol Polymers 0.000 claims description 4
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- 239000001863 hydroxypropyl cellulose Substances 0.000 claims description 3
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- 230000008878 coupling Effects 0.000 description 13
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- 238000005859 coupling reaction Methods 0.000 description 13
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
序号 | 理化技术指标 | 单位 | 量值 |
1 | 装量 | g | 20g/管 |
2 | 粘度 | Pa.s/m | ≥15 |
3 | pH值 | / | 7.2 |
4 | 声速(35℃) | m/s | 1580 |
5 | 声抗阻力(35℃) | Pa.s/m | 1.587×106 |
6 | 声衰减(35℃) | dB/(cm.MHz) | 0.23 |
序号 | 性能指标 | 单位 | 量值 |
1 | 细菌菌落总数 | cfu/g | ≤20 |
2 | 真菌菌落总数 | cfu/g | 0 |
3 | 大肠杆菌 | cfu/g | 0 |
4 | 绿脓杆菌 | cfu/g | 0 |
5 | 金黄色葡萄球菌 | cfu/g | 0 |
6 | 溶血性链球菌 | cfu/g | 0 |
检测项目 | 检测标准 | 检测结果 | 结论 |
细菌总数 | 0 | 0 | 合格 |
金黄色葡萄球菌 | 杀灭率≥99.9% | ≥99.99% | 合格 |
大肠杆菌 | 杀灭率≥99.9% | ≥99.99% | 合格 |
绿脓杆菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
产气杆菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
粪产杆菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
荧光假单胞菌 | 杀灭率≥90.0% | ≥99.00% | 合格 |
黄曲霉菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
变形杆菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
枯草芽孢杆菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
白色念珠菌 | 杀灭率≥90.0% | ≥99.00% | 合格 |
乙肝表面抗原 | 杀灭率≥99.9% | 100% | 合格 |
序号 | 理化技术指标 | 单位 | 量值 |
1 | 装量 | g | 20g/管 |
2 | 粘度 | Pa.s/m | ≥15 |
3 | pH值 | / | 7.0 |
4 | 声速(35℃) | m/s | 1590 |
5 | 声抗阻力(35℃) | Pa.s/m | 1.601×106 |
6 | 声衰减(35℃) | dB/(cm.MHz) | 0.23 |
序号 | 性能指标 | 单位 | 量值 |
1 | 细菌菌落总数 | cfu/g | ≤20 |
2 | 真菌菌落总数 | cfu/g | 0 |
3 | 大肠杆菌 | cfu/g | 0 |
4 | 绿脓杆菌 | cfu/g | 0 |
5 | 金黄色葡萄球菌 | cfu/g | 0 |
6 | 溶血性链球菌 | cfu/g | 0 |
检测项目 | 检测标准 | 检测结果 | 结论 |
细菌总数 | 0 | 0 | 合格 |
金黄色葡萄球菌 | 杀灭率≥99.9% | ≥99.99% | 合格 |
大肠杆菌 | 杀灭率≥99.9% | ≥99.99% | 合格 |
绿脓杆菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
产气杆菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
粪产杆菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
荧光假单胞菌 | 杀灭率≥90.0% | ≥99.00% | 合格 |
黄曲霉菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
变形杆菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
枯草芽孢杆菌 | 杀灭率≥99.9% | ≥99.90% | 合格 |
白色念珠菌 | 杀灭率≥90.0% | ≥99.00% | 合格 |
乙肝表面抗原 | 杀灭率≥99.9% | 100% | 合格 |
序号 | 理化技术指标 | 单位 | 量值 |
1 | 装量 | g | 20g/管 |
2 | 粘度 | Pa.s/m | ≥15 |
3 | pH值 | / | 7.0 |
4 | 声速(35℃) | m/s | 1578 |
5 | 声抗阻力(35℃) | Pa.s/m | 1.585×106 |
6 | 声衰减(35℃) | dB/(cm.MHz) | 0.22 |
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN2011100317446A CN102085382B (zh) | 2011-01-28 | 2011-01-28 | 一种眼科专用杀菌型医用超声耦合剂及制备方法 |
Applications Claiming Priority (1)
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CN2011100317446A CN102085382B (zh) | 2011-01-28 | 2011-01-28 | 一种眼科专用杀菌型医用超声耦合剂及制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN102085382A true CN102085382A (zh) | 2011-06-08 |
CN102085382B CN102085382B (zh) | 2012-11-28 |
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CN2011100317446A Expired - Fee Related CN102085382B (zh) | 2011-01-28 | 2011-01-28 | 一种眼科专用杀菌型医用超声耦合剂及制备方法 |
Country Status (1)
Country | Link |
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CN (1) | CN102085382B (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102430131A (zh) * | 2011-12-06 | 2012-05-02 | 董莉霞 | 抗菌型医用超声耦合剂及其制备方法 |
CN108653040A (zh) * | 2018-07-09 | 2018-10-16 | 南昌辉正生物技术有限公司 | 一种水凝胶修复面膜及其制备方法 |
CN112741671A (zh) * | 2019-10-29 | 2021-05-04 | 王强 | 一种体外冲击波碎石用能量介导液及其制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060246111A1 (en) * | 2005-04-19 | 2006-11-02 | Smith Larry L | Polysaccharides as ultrasound transmission media |
CN101716354A (zh) * | 2009-12-04 | 2010-06-02 | 广东工业大学 | 一种超声耦合剂和应用 |
-
2011
- 2011-01-28 CN CN2011100317446A patent/CN102085382B/zh not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060246111A1 (en) * | 2005-04-19 | 2006-11-02 | Smith Larry L | Polysaccharides as ultrasound transmission media |
CN101716354A (zh) * | 2009-12-04 | 2010-06-02 | 广东工业大学 | 一种超声耦合剂和应用 |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102430131A (zh) * | 2011-12-06 | 2012-05-02 | 董莉霞 | 抗菌型医用超声耦合剂及其制备方法 |
CN108653040A (zh) * | 2018-07-09 | 2018-10-16 | 南昌辉正生物技术有限公司 | 一种水凝胶修复面膜及其制备方法 |
CN112741671A (zh) * | 2019-10-29 | 2021-05-04 | 王强 | 一种体外冲击波碎石用能量介导液及其制备方法 |
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CN102085382B (zh) | 2012-11-28 |
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Denomination of invention: The invention relates to a bactericidal medical ultrasonic coupling agent for ophthalmology and a preparation method thereof Effective date of registration: 20211216 Granted publication date: 20121128 Pledgee: Wuhan area branch of Hubei pilot free trade zone of Bank of China Ltd. Pledgor: Wuhan Coupling Medicine Technology Co.,Ltd. Registration number: Y2021420000144 |
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