CN102046815A - 用于病毒检测的方法 - Google Patents

用于病毒检测的方法 Download PDF

Info

Publication number
CN102046815A
CN102046815A CN2009801211596A CN200980121159A CN102046815A CN 102046815 A CN102046815 A CN 102046815A CN 2009801211596 A CN2009801211596 A CN 2009801211596A CN 200980121159 A CN200980121159 A CN 200980121159A CN 102046815 A CN102046815 A CN 102046815A
Authority
CN
China
Prior art keywords
virus
sample
antigen
concentration
sensor surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2009801211596A
Other languages
English (en)
Chinese (zh)
Inventor
P·博格
A·弗罗斯特尔-卡尔森
M·哈马莱南
A·拉森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cytiva Sweden AB
Original Assignee
GE Healthcare Bio Sciences AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Bio Sciences AB filed Critical GE Healthcare Bio Sciences AB
Publication of CN102046815A publication Critical patent/CN102046815A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/10—Competitive assay format

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN2009801211596A 2008-06-02 2009-06-01 用于病毒检测的方法 Pending CN102046815A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE0801304 2008-06-02
SE0801304-7 2008-06-02
SE0950272 2009-04-24
SE0950272-5 2009-04-24
PCT/SE2009/050637 WO2009148395A1 (en) 2008-06-02 2009-06-01 Method for virus detection

Publications (1)

Publication Number Publication Date
CN102046815A true CN102046815A (zh) 2011-05-04

Family

ID=41398332

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2009801211596A Pending CN102046815A (zh) 2008-06-02 2009-06-01 用于病毒检测的方法
CN200980121158.1A Active CN102046814B (zh) 2008-06-02 2009-06-01 浓度测定

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN200980121158.1A Active CN102046814B (zh) 2008-06-02 2009-06-01 浓度测定

Country Status (6)

Country Link
US (3) US20110070574A1 (https=)
EP (2) EP2294227B1 (https=)
JP (2) JP2011522249A (https=)
CN (2) CN102046815A (https=)
AU (2) AU2009255776A1 (https=)
WO (2) WO2009148395A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107615065A (zh) * 2015-03-23 2018-01-19 英特里希特公司 对生物材料评估腺病毒或腺相关病毒的病毒类型的非缔合的病毒尺寸颗粒

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2294227B1 (en) * 2008-06-02 2015-08-12 GE Healthcare Bio-Sciences AB Concentration assay
WO2012174014A2 (en) * 2011-06-13 2012-12-20 Indevr, Inc. Low density microarrays for vaccine related protein quantification, potency determination and efficacy evaluation
EP2657681A1 (en) * 2012-04-26 2013-10-30 Roche Diagnostics GmbH Improvement of the sensitivity and the dynamic range of photometric assays by generating multiple calibration curves
US20150093839A1 (en) * 2013-10-02 2015-04-02 General Electric Company Methods and systems for detection of target and applications thereof
US20160313316A1 (en) * 2013-12-10 2016-10-27 Agency For Science, Technology And Research Surface acoustic wave sensor for influenza detection
AU2014384759B2 (en) 2014-02-28 2021-07-22 Nitto Denko Corporation Urinalysis device and dry reagent for quantitative urinalysis
WO2015187158A1 (en) 2014-06-04 2015-12-10 Indevr, Inc. Universal capture array for multiplexed subtype-specific quantification and stability determination of influenza proteins
GB201511587D0 (en) * 2015-07-02 2015-08-19 Ge Healthcare Bio Sciences Ab A method and a system for determining a concentration range for a sample by means of a calibration curve
US20170212050A1 (en) * 2016-01-22 2017-07-27 Ionfield Holdings, Llc Method for calibrating and using calibration of microplates
EP3296741B1 (en) * 2016-09-14 2019-08-21 Serum Institute of India Private Limited Multiplex bead based assay for quantification of multiple types of carrier protein in a multivalent conjugate vaccine composition
CN110044997B (zh) * 2018-01-15 2023-08-04 中国医学科学院药物研究所 一种体内药物的离子强度虚拟校正和定量质谱成像分析方法
GB2578163A (en) * 2018-10-19 2020-04-22 Univ Pretoria Plant produced avian influenza antigens and their uses in diagnostic assays and devices
JP7233880B2 (ja) * 2018-10-22 2023-03-07 キヤノンメディカルシステムズ株式会社 ウイルスｒｎａ単離方法及びウイルス定量方法
CN111487405A (zh) * 2020-04-03 2020-08-04 山东泰邦生物制品有限公司 一种快速高通量定量检测病毒特异性抗体的方法
CN112255212B (zh) * 2020-10-15 2022-08-05 天津大学 检测h5n1甲型流感病毒血凝素的方法
CN112557647B (zh) * 2020-12-10 2024-07-05 宁波华仪宁创智能科技有限公司 基于免疫层析技术的检测方法及应用
CN112964870B (zh) * 2021-02-03 2024-01-26 军事科学院军事医学研究院军事兽医研究所 一种基于spr生物传感器的流感病毒快速检测方法
US20240151626A1 (en) * 2022-11-04 2024-05-09 American Ecotech L.C. Mass concentration determination of particles smaller than 2.5 microns in air
DE102022134580A1 (de) * 2022-12-22 2024-06-27 Endress+Hauser Conducta Gmbh+Co. Kg Verfahren zum Kalibrieren eines Sensors im laufenden Betrieb, Sensor mit implementiertem Verfahren zur Kalibration

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0973023A1 (en) * 1998-07-14 2000-01-19 Texas Instruments Incorporated High throughput surface plasmon resonance analysis system
WO2006041392A1 (en) * 2004-10-13 2006-04-20 Biacore Ab Preparation and use of a reactive solid support surface

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85137A (en) 1987-01-21 1992-02-16 Ares Serono Res & Dev Ltd Method of assaying for a ligand using surface plasmon resonance effect
SE462454B (sv) * 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
SE462408B (sv) * 1988-11-10 1990-06-18 Pharmacia Ab Optiskt biosensorsystem utnyttjande ytplasmonresonans foer detektering av en specific biomolekyl, saett att kalibrera sensoranordningen samt saett att korrigera foer baslinjedrift i systemet
SE8804074D0 (sv) * 1988-11-10 1988-11-10 Pharmacia Ab Sensorenhet och dess anvaendning i biosensorsystem
JPH0354467A (ja) 1989-07-24 1991-03-08 Asahi Chem Ind Co Ltd ウイルス濃度の測定方法および測定装置
GB9518429D0 (en) 1995-09-08 1995-11-08 Pharmacia Biosensor A rapid method for providing kinetic and structural data in molecular interaction analysis
JP3645023B2 (ja) * 1996-01-09 2005-05-11 富士写真フイルム株式会社 試料分析方法、検量線の作成方法及びそれを用いる分析装置
SE9604575D0 (sv) 1996-12-12 1996-12-12 Biacore Ab Method and system for analyte determination
PL355287A1 (en) * 1999-09-24 2004-04-05 Smithkline Beecham Biologicals S.A. Intranasal influenza virus vaccine
JP3515101B2 (ja) * 2000-06-27 2004-04-05 中外製薬株式会社 リガンドとリガンド結合蛋白質との結合活性を評価する方法
US6477392B1 (en) * 2000-07-14 2002-11-05 Futrex Inc. Calibration of near infrared quantitative measurement device using optical measurement cross-products
AU2005257705A1 (en) 2004-06-24 2006-01-05 Ge Healthcare Bio-Sciences Ab Method for detecting molecular surface interactions
SE0402476D0 (sv) * 2004-10-13 2004-10-13 Biacore Ab Preparation and use of a reactive solid support surface
FR2921928B1 (fr) * 2007-10-08 2011-03-04 Sanofi Pasteur Anticorps monoclonaux specifiques de l'hemagglutinine du virus grippal
EP2294227B1 (en) * 2008-06-02 2015-08-12 GE Healthcare Bio-Sciences AB Concentration assay

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0973023A1 (en) * 1998-07-14 2000-01-19 Texas Instruments Incorporated High throughput surface plasmon resonance analysis system
WO2006041392A1 (en) * 2004-10-13 2006-04-20 Biacore Ab Preparation and use of a reactive solid support surface

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
付伟灵等: "《临床检验学实用技术与新进展》", 31 July 2005 *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107615065A (zh) * 2015-03-23 2018-01-19 英特里希特公司 对生物材料评估腺病毒或腺相关病毒的病毒类型的非缔合的病毒尺寸颗粒
CN107636444A (zh) * 2015-03-23 2018-01-26 英特里希特公司 用于评估生物材料中的流感病毒类型的非缔合的病毒尺寸颗粒的流式细胞术方法
US10408734B2 (en) 2015-03-23 2019-09-10 Essen Instruments, Inc. Flow cytometry evaluation of biological material for unassociated virus particles in presence of unbound flourescent antibody stain
US10545084B2 (en) 2015-03-23 2020-01-28 Essen Instruments, Inc. Flow cytometry evaluation of biological material for exosome particles
US10585030B2 (en) 2015-03-23 2020-03-10 Essen Instruments, Inc. Evaluating biological material for unassociated virus-like particles
CN107636444B (zh) * 2015-03-23 2020-07-10 以埃森生物科学股份有限公司的名义经营的埃森仪器股份有限公司 用于评估生物材料中的流感病毒类型的非缔合的病毒尺寸颗粒的流式细胞术方法
CN107615065B (zh) * 2015-03-23 2020-07-24 以埃森生物科学股份有限公司的名义经营的埃森仪器股份有限公司 对生物材料评估腺病毒或腺相关病毒的病毒类型的非缔合的病毒尺寸颗粒
US10739246B2 (en) 2015-03-23 2020-08-11 Essen Instruments, Inc. Flow cytometry evaluation for unassociated virus-size particles having an adenovirus epitope
US11585813B2 (en) 2015-03-23 2023-02-21 Sartorius Bioanalytical Instruments, Inc. Flow cytometry evaluation for virus-size particles with antibody stain having low fluorophore ratio
US12169201B2 (en) 2015-03-23 2024-12-17 Sartorious BioAnalytical Instruments, Inc. Antibody stain with low fluorophore ratio for staining virus-size particles
US12339283B2 (en) 2015-03-23 2025-06-24 Sartorius BioAnalytical Intruments, Inc. Flow cytometry evaluation of biological material for unassociated virus-size particles

Also Published As

Publication number Publication date
JP5730192B2 (ja) 2015-06-03
WO2009148395A1 (en) 2009-12-10
EP2294226A1 (en) 2011-03-16
JP2011522250A (ja) 2011-07-28
JP2011522249A (ja) 2011-07-28
AU2009255776A1 (en) 2009-12-10
CN102046814A (zh) 2011-05-04
US10823677B2 (en) 2020-11-03
EP2294227B1 (en) 2015-08-12
AU2009255777A1 (en) 2009-12-10
EP2294227A1 (en) 2011-03-16
CN102046814B (zh) 2015-05-20
WO2009148396A1 (en) 2009-12-10
US20110076703A1 (en) 2011-03-31
EP2294226A4 (en) 2011-09-28
US20110070574A1 (en) 2011-03-24
EP2294227A4 (en) 2011-10-12
US20210215613A1 (en) 2021-07-15

Similar Documents

Publication Publication Date Title
CN102046815A (zh) 用于病毒检测的方法
JP5487200B2 (ja) せん断垂直弾性表面波一体型表面プラズモン共鳴センシング装置および方法
EP2903740A2 (en) One-step biomolecular immobilisation procedure and products thereof
US20140141529A1 (en) Method of determining active concentration by calibration-free analysis
JP7345790B2 (ja) センサー表面でアナライト－リガンド結合を測定するための方法
Moran et al. Surface Plasmon resonance–based immunoassays: approaches, performance, and applications
JP4068148B2 (ja) アッセイ法
Serafin et al. Antibody-independent surface plasmon resonance assays for influenza vaccine quality control
Terao et al. Fast protein detection in raw blood by size-exclusion SPR sensing
US20130017624A1 (en) Method for determination of binding stoichiometry
WO2012029694A1 (ja) Ａ型インフルエンザウイルス核タンパク質の第１００番アミノ酸がアルギニンであるか否かを判定する方法
JP5782690B2 (ja) 抗ｎｐ−ｈ２８９抗体の作製方法
EP2313777B1 (en) A method of characterizing antibodies
Cho et al. Minimum-step immuno-analysis based on continuous recycling of the capture antibody
KR102954997B1 (ko) SARS-CoV-2 스파이크 단백질 특이적 항체를 활용한 진단용 키트
Occhicone et al. Comparative performance of three optical biosensing platforms for SARS-CoV-2 antibodies detection in human serum
Bütün et al. A Surface Acoustic Wave Biosensor for Early Cancer Diagnosis
WO2026068442A1 (en) Concentration assessment
Ramakrishna et al. A wash-free, dip-type fiber optic plasmonic (DiP) assay for sub-zeptomole analyte detection
Winheim et al. Development and qualification of a generic IgG quantification assay using surface plasmon resonance
CN119968559A (zh) 用于spr分析的流动池中的流体的空气分段注射
Rosti et al. Assessment of molecular recognition element for the quantification of human epidermal growth factor using surface plasmon resonance

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20110504