CN102026643A - 法舒地尔化合物的用途、方法及其药物组合物 - Google Patents
法舒地尔化合物的用途、方法及其药物组合物 Download PDFInfo
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- CN102026643A CN102026643A CN2009801229640A CN200980122964A CN102026643A CN 102026643 A CN102026643 A CN 102026643A CN 2009801229640 A CN2009801229640 A CN 2009801229640A CN 200980122964 A CN200980122964 A CN 200980122964A CN 102026643 A CN102026643 A CN 102026643A
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- fasudil
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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Abstract
本发明提供一种法舒地尔的新用途,即法舒地尔在诱导成年脑神经干细胞再生和/或保护神经功能以及预防和/或治疗与神经元损伤和/或死亡相关疾病中的用途。本发明提供的法舒地尔具体用途包括在制备用于诱导成年脑神经干细胞再生和/或保护神经功能的药物中的用途,制备用于预防和/或治疗与神经元损伤和/或死亡相关疾病的药物中的用途。
Description
PCT国内申请,说明书已公开。
Claims (1)
- PCT国内申请,权利要求书已公开。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2009801229640A CN102026643B (zh) | 2008-06-26 | 2009-05-11 | 法舒地尔化合物的用途、方法及其药物组合物 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200810126351A CN101612157A (zh) | 2008-06-26 | 2008-06-26 | 法舒地尔诱导成年脑内源性神经干细胞再生的用途 |
CN200810126351.1 | 2008-06-26 | ||
CN2009801229640A CN102026643B (zh) | 2008-06-26 | 2009-05-11 | 法舒地尔化合物的用途、方法及其药物组合物 |
PCT/CN2009/000509 WO2009155777A1 (zh) | 2008-06-26 | 2009-05-11 | 法舒地尔化合物的用途、方法及其药物组合物 |
Publications (2)
Publication Number | Publication Date |
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CN102026643A true CN102026643A (zh) | 2011-04-20 |
CN102026643B CN102026643B (zh) | 2013-05-01 |
Family
ID=41443982
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200810126351A Pending CN101612157A (zh) | 2008-06-26 | 2008-06-26 | 法舒地尔诱导成年脑内源性神经干细胞再生的用途 |
CN2009801229640A Active CN102026643B (zh) | 2008-06-26 | 2009-05-11 | 法舒地尔化合物的用途、方法及其药物组合物 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200810126351A Pending CN101612157A (zh) | 2008-06-26 | 2008-06-26 | 法舒地尔诱导成年脑内源性神经干细胞再生的用途 |
Country Status (2)
Country | Link |
---|---|
CN (2) | CN101612157A (zh) |
WO (1) | WO2009155777A1 (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2644238T3 (es) | 2012-03-12 | 2017-11-28 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts Universitätsmedizin | Inhibidores de rho-quinasas para uso en el tratamiento de la esclerosis lateral amiotrófica |
CN102973571A (zh) * | 2012-12-12 | 2013-03-20 | 天津红日药业股份有限公司 | 法舒地尔的新用途 |
CN104557897B (zh) * | 2014-04-10 | 2017-10-27 | 中山大学 | 法舒地尔‑硫辛酸二联体的合成及其应用 |
CN104983704A (zh) * | 2015-08-13 | 2015-10-21 | 青岛蓝盛洋医药生物科技有限责任公司 | 一种改善脑血管痉挛的药物盐酸法舒地尔组合物片剂 |
CN105055332A (zh) * | 2015-09-10 | 2015-11-18 | 青岛蓝盛洋医药生物科技有限责任公司 | 一种治疗缺血性脑血管疾病的药物盐酸法舒地尔组合物干混悬剂 |
JP2023509970A (ja) | 2020-01-09 | 2023-03-10 | ウールジー・ファーマシューティカルズ・インコーポレイテッド | 皮質性認知症に関連する徘徊を治療する方法 |
EP4125879A4 (en) | 2020-03-25 | 2024-04-03 | Woolsey Pharmaceuticals, Inc. | METHODS OF TREATMENT OF SPATIO-TEMPORAL DISORIENTATION ASSOCIATED WITH PROTEINOPATHY |
WO2022086581A1 (en) | 2020-10-22 | 2022-04-28 | Woolsey Pharmaceuticals, Inc | Methods of treating 4-repeat tauopathies |
CN113440649A (zh) * | 2021-05-31 | 2021-09-28 | 温州医科大学 | 一种用于定向诱导轴突再生的纺丝膜支架 |
CA3236462A1 (en) | 2021-11-29 | 2023-06-01 | Woolsey Pharmaceuticals, Inc. | Methods of treating agitation and other dementia-associated behavioral symptoms |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005117896A1 (de) * | 2004-06-03 | 2005-12-15 | Schering Aktiengesellschaft | Formulierungen, die fasudil, eine matrix und einem mantel enthalten |
CN1729985A (zh) * | 2005-08-02 | 2006-02-08 | 吴良信 | 盐酸法舒地尔注射液及其制备方法 |
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2008
- 2008-06-26 CN CN200810126351A patent/CN101612157A/zh active Pending
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2009
- 2009-05-11 CN CN2009801229640A patent/CN102026643B/zh active Active
- 2009-05-11 WO PCT/CN2009/000509 patent/WO2009155777A1/zh active Application Filing
Also Published As
Publication number | Publication date |
---|---|
CN102026643B (zh) | 2013-05-01 |
CN101612157A (zh) | 2009-12-30 |
WO2009155777A1 (zh) | 2009-12-30 |
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